Select a section from the left sidebar
Beta-sitosterol
- Family: Plantae - Sapotaceae
- Kingdom: Plantae, Animalia
-
Class: Steroid
- Subclass: Phytosterol
Canonical Smiles | CC[C@H](CC[C@@H](C)[C@H]1CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2CC=C4[C@@]3(CC[C@@H](C4)O)C)C)C(C)C |
---|---|
InChI | InChI=1S/C29H50O/c1-7-21(19(2)3)9-8-20(4)25-12-13-26-24-11-10-22-18-23(30)14-16-28(22,5)27(24)15-17-29(25,26)6/h10,19-21,23-27,30H,7-9,11-18H2,1-6H3/t20-,21-,23+,24+,25-,26+,27+,28+,29-/m1/s1 |
InChIKey | KZJWDPNRJALLNS-VJSFXXLFSA-N |
Formula | C29H50O |
HBA | 1 |
HBD | 1 |
MW | 414.72 |
Rotatable Bonds | 6 |
TPSA | 20.23 |
LogP | 8.02 |
Number Rings | 4 |
Number Aromatic Rings | 0 |
Heavy Atom Count | 30 |
Formal Charge | 0 |
Fraction CSP3 | 0.93 |
Exact Mass | 414.39 |
Number of Lipinski Rule Violations | 1 |
# | Species | Family | Kingdom | NCBI Taxonomy ID |
---|---|---|---|---|
1 | Agave decipiens | Agavaceae | Plantae | 2695036 |
2 | Periploca laevigata | Apocynaceae | Plantae | 413294 |
3 | Solenostemma argel | Apocynaceae | Plantae | 219273 |
4 | Sabal causiarum | Arecaceae | Plantae | 469726 |
5 | Hyphaene thebaica | Arecaceae | Plantae | 115479 |
6 | Parmentiera cereifera | Bignoniaceae | Plantae | 163100 |
7 | Callyspongia aff. implexa | Callyspongiidae | Animalia | 178537 |
8 | Campanula medium | Campanulaceae | Plantae | 56154 |
9 | Helianthemum sessiliflorum | Cistaceae | Plantae | 2650562 |
10 | Euphorbia guyoniana | Euphorbiaceae | Plantae | 1138347 |
11 | Euphorbia helioscopia | Euphorbiaceae | Plantae | 154990 |
12 | Euphorbia bupleuroides | Euphorbiaceae | Plantae | 1532838 |
13 | Limonium axillare | Plumbaginaceae | Plantae | 114150 |
14 | Eragrostis tef | Poaceae | Plantae | 110835 |
15 | Salix subserrata | Salicaceae | Plantae | 753747 |
16 | Ammi majus | Apiaceae | Plantae | 48026 |
17 | Ferula lutea | Apiaceae | Plantae | 52470 |
18 | Bunium incrassatum | Apiaceae | Plantae | 1094602 |
19 | Aloe sinkatana | Asphodelaceae | Plantae | 210945 |
20 | Lantana montevidensis | Verbenaceae | Plantae | 1241423 |
21 | Chrysanthemum macrocarpum | Asteraceae | Plantae | 13422 |
22 | Centaurea africana | Asteraceae | Plantae | 2950952 |
23 | Centaurea omphalotricha | Asteraceae | Plantae | 41503 |
24 | Echinops galalensis | Asteraceae | Plantae | 32194 |
25 | Francoeuria crispa | Asteraceae | Plantae | 1548540 |
26 | Gaillardia aristata | Asteraceae | Plantae | 55624 |
27 | Inula crithmoides | Asteraceae | Plantae | 119182 |
28 | Lactuca sativa | Asteraceae | Plantae | 4236 |
29 | Pulicaria arabica | Asteraceae | Plantae | 119185 |
30 | Scorzonera undulata | Asteraceae | Plantae | 268100 |
31 | Sonchus macrocarpus | Asteraceae | Plantae | 2984305 |
32 | Hypericum quartinianum | Hypericaceae | Plantae | 1137015 |
33 | Raphia vinifera | Arecaceae | Plantae | 1966430 |
34 | Conyza aegyptiaca | Asteraceae | Plantae | 741633 |
35 | Symphonia globulifera | Clusiaceae | Plantae | 156483 |
36 | Symphonia globulifera | Guttiferae | Plantae | 156483 |
37 | Fagara heitzii | Rutaceae | Plantae | — |
38 | Baillonella toxisperma (Pierre) | Sapotaceae | Plantae | 568230 |
Showing of synonyms
Beta-sitosterol
Sitosterol
Cupreol
Azuprostat
Quebrachol
22,23-Dihydrostigmasterol
Cinchol
Triastonal
Rhamnol
Beta-Sitosterin
Nimbosterol
Prostasal
Alpha-Dihydrofucosterol
Sito-Lande
24alpha-Ethylcholesterol
Beta Sitosterol
Stigmast-5-en-3beta-ol
(24R)-Ethylcholest-5-en-3beta-ol
Alpha-Phytosterol
Angelicin (steroid)
Sitosterin
(3beta)-Stigmast-5-en-3-ol
Betaprost
(24R)-Stigmast-5-en-3beta-ol
Beta-sistosterol
SITOSTEROL, BETA-
SKF 14463
SITOSTEROL, BETA
CHEBI:27693
NSC8096
24-alpha-Ethylcholesterol
Stigmast-5-en-3-ol, (3beta)-
UNII-S347WMO6M4
Delta5-Stigmasten-3-beta-ol
CCRIS 5529
S347WMO6M4
DTXSID5022481
Stigmasterol, 22,23-dihydro-
(3-beta)-Stigmast-5-en-3-ol
NSC 8096
NSC-8096
EINECS 201-480-6
NSC 18173
NSC-18173
NSC-49083
AI3-26020
DTXCID802481
NSC18173
SITOSTEROL (MART.)
SITOSTEROL [MART.]
BETA-SITOSTEROL (USP-RS)
BETA-SITOSTEROL [USP-RS]
5-Stigmasten-3beta-ol
I2-sitosterol
Beta-Sitosterol-2
3 beta-stigmast-5-en-3-ol
5-cholesten-24-ethyl-3-ol
Delta(SUP 5)-STIGMASTEN-3beta-OL
Beta-SITOSTEROL (CONSTITUENT OF PYGEUM)
24beta-ETHYL-delta(SUP 5)-CHOLESTEN-3beta-OL
BETA-SITOSTEROL (CONSTITUENT OF SAW PALMETTO)
Corn sterilized quantitative extract (beta sitosterol)
BETA-SITOSTEROL (CONSTITUENT OF STINGING NETTLE)
201-480-6
Beta-SITOSTEROL (CONSTITUENT OF ECHINACEA ANGUSTIFOLIA ROOT, ECHINACEA PALLIDA ROOT, ECHINACEA PURPUREA ROOT AND ECHINACEA PURPUREA AERIAL PARTS)
83-46-5
Harzol
(-)-beta-Sitosterol
B-Sitosterol
Sobatum
A-Dihydrofucosterol
.alpha.-Dihydrofucosterol
CHEMBL221542
.beta.-Sitosterol
NSC49083
.alpha.-Phytosterol
Sitosterol, .beta.
(3S,8S,9S,10R,13R,14S,17R)-17-[(2R,5R)-5-ethyl-6-methylheptan-2-yl]-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-ol
B-Sitosterol (Synthetic)
Stigmasterol,23-dihydro-
.beta.-Sitosterin
MFCD00003631
Stigmast-5-en-3-ol, (3.beta.)-
24.alpha.-Ethylcholesterol
Stigmast-5-en-3-ol, (3b)-
Stigmast-5-en-3.beta.-ol
SR-05000002307
Beta-Sitosterol (purity>98%)
Stigmast-5-en-3-beta-ol
Sitosterol beta
A-Phytosterol
B-Sitosterin
Beta-Phytosterol
Ss--Sitosterol
.beta.Sitosterin
.beta.Sitosterol
Beta -Sitosterol
CAS-83-46-5
NCGC00095716-01
(3S,8S,9S,10R,13R,14S,17R)-17-[(1R,4R)-4-ethyl-1,5-dimethyl-hexyl]-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-ol
(-)-b-Sitosterol
Harzol (TN)
24a-Ethylcholesterol
Alpha.Dihydrofucosterol
D5-Stigmasten-3b-ol
Stigmast-5-en-3b-ol
B-Sitosterol - 40%
B-Sitosterol - 80%
Prestwick0_000985
Prestwick1_000985
Prestwick2_000985
Prestwick3_000985
?-Sitosterol - 70%
Delta5-Stigmasten-3b-ol
Beta-Sitosterol, >=70%
Beta-Sitosterol (Standard)
Beta-sitosterol [WHO-DD]
BIDD:PXR0121
SCHEMBL16105
22,23-dihydro-Stigmasterol
BSPBio_001049
BIDD:ER0636
SPBio_002950
BPBio1_001155
MEGxp0_001710
BETA SITOSTEROL [VANDF]
.BETA.-SITOSTEROL [MI]
(24R)-Stigmast-5-en-3b-ol
ACon1_000287
HY-N0171R
CHEBI:176889
HMS1571E11
HMS2098E11
(24R)-Ethylcholest-5-en-3b-ol
24-Ethylcholest-5-en-3.beta.-ol
MSK40101
Beta-Sitosterol, analytical standard
Tox21_111514
BDBM50218197
Beta-Sitosterol, synthetic, >=95%
LMST01040129
NSC821067
S2273
AKOS005267194
AT37227
BETA-SITOSTEROL, 40% (HPLC)
CCG-208334
DB14038
FS12899
FS16412
FS29792
NSC-821067
Beta-Sitosterol, from soybean, >=96%
SMP1_000274
NCGC00142598-02
NCGC00142598-03
NCGC00142598-08
(3.BETA.)-STIGMAST-5-EN-3-OL
(3S,8S,9S,10R,13R,14S,17R)-17-((2R,5R)-5-ethyl-6-methylheptan-2-yl)-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-ol
14-((1S,4R)-4-ethyl-1,5-dimethylhexyl)(1S,5S,10S,11S,2R,14R,15R)-2,15-dimethyl tetracyclo[8.7.0.0<2,7>.0<11,15>]heptadec-7-en-5-ol
1ST40101
AC-24183
BP-40650
NCI60_041777
AB00513984
NS00078818
S0040
.DELTA.(SUP 5)-STIGMASTEN-3.BETA.-OL
C01753
D08518
A840577
AA-504/07226009
Alpha-Dihydrofucosterol, 22,23-Dihydrostigmasterol
SR-05000002307-2
SR-05000002307-3
BRD-K79402892-001-06-7
Q63409374
.BETA.-SITOSTEROL (CONSTITUENT OF PYGEUM) [DSC]
BETA-SITOSTEROL (CONSTITUENT OF SAW PALMETTO) [DSC]
BETA-SITOSTEROL, inverted exclamation markY 98% (HPLC)
Beta-Sitosterol, analytical standard, from soybean, >=40%
Beta-Sitosterol, primary pharmaceutical reference standard
24.BETA.-ETHYL-.DELTA.(SUP 5)-CHOLESTEN-3.BETA.-OL
BETA-SITOSTEROL (CONSTITUENT OF STINGING NETTLE) [DSC]
Beta-sitosterol, European Pharmacopoeia (EP) Reference Standard
-Sitosterol (purity>98%)
22,23-Dihydrostigmasterol (purity>98%)
Beta-Sitosterol, United States Pharmacopeia (USP) Reference Standard
Beta-Sitosterol, certified reference material, 100 mug/mL in chloroform
17-(5-ethyl-6-methyl-heptan-2-yl)-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-ol
76772-70-8
- Mahmoud ZF, Salam NAA, et al. (1981). A carotane derivative and a eudesmanolide from Inula crithmoides. Phytochemistry,1981,20(4),735-738. [View]
- Seghiri R, Boumaza O, et al. (2009). A flavonoid with cytotoxic activity and other constituents from Centaurea africana. Phytochemistry Letters,2009,2(3),114-118. [View]
- Kandil FE, Ahmed KM, et al. (2000). A new flavonoid from Limonium axillare. Archiv der Pharmazie,2000,333(8),275-277. [View] [PubMed]
- Boutaghane N, Voutquenne-Nazabadioko L, et al. (2013). A new triterpenic diester from the aerial parts of Chrysanthemum macrocarpum. Phytochemistry Letters,2013,6,519-525. [View]
- Selim YA, Ouf NH. (2012). Anti-inflammatory new coumarin from the Ammi majus L.. Organic and Medicinal Chemistry Letters,2012,2,1. [View] [PubMed]
- Ngouela S, Lenta BN, et al. (2006). Anti-plasmodial and antioxidant activities of constituents of the seed shells of Symphonia globulifera Linn f.. Phytochemistry,2006, 67(3), 302-306. [View] [PubMed]
- Abdelmohsen UR, Cheng C, et al. (2015). Antichlamydial sterol from the Red Sea sponge Callyspongia aff. Implexa.. Planta Medica,2015,81(5),382-387. [View] [PubMed]
- Assiri AMA, Ramadan MF, et al. (2014). Bioactive compounds and antiradical potential of Campanula medium lipids.. Chemistry of Natural Compounds,2014,50(6),1088-1091. [View]
- Hafez S, Sarg TM, et al. (1987). Caryophyllene derivatives from Pulicaria arabica. Phytochemistry,1987,26(12),3356-3358. [View]
- El-Alfy TS, Ezzat SM, et al. (2012). Chemical and biological study of the seeds of Eragrostis tef (Zucc.) Trotter. Natural Product Research,2012,26(7),619-629. [View] [PubMed]
- Hussain H, Badawy A, et al. (2011). Chemical constituents and antimicrobial activity of Salix subserrata. Records of Natural Products,2011,5(2),133-137. [View]
- Mouffok S, Haba H, et al. (2012). Chemical constituents of Centaurea omphalotricha Coss. & Durieu ex Batt. & Trab.. Records of Natural Products,2012,6(3),292-295. [View]
- Fobofou SAT, Ares K, et al. (2019). Chemical constituents of Hypericum quartinianum (Hypericaceae), a sub-Saharan African plant species.. Biochemical Systematics and Ecology,2019,85,46-49.. [View] [PubMed]
- Bousetla A, Zellagui A, et al. (2015). Chemical constituents of the roots of Algerian Bunium incrassatum and evaluation of its antimicrobial activity. Arabian Journal of Chemistry,2015,8,313-316. [View]
- Nguengang RT, Tchegnitegni BT, et al. (2023). Constituents of the Stem Bark of Symphonia globulifera Linn. f. with Antileishmanial and Antibacterial Activities. Molecules. 2023, 28(6), 2473. [View] [PubMed]
- Salama MM, Kandil ZA and Islam WT. (2012). Cytotoxic compounds from the leaves of Gaillardia aristata Pursh. growing in Egypt. Natural Product Research,2012,26(22),2057-2062. [View] [PubMed]
- Haba H, Lavaud C, et al. (2007). Diterpenoids and triterpenoids from Euphorbia guyoniana. Phytochemistry,2007,68,1255-1260. [View] [PubMed]
- Mohamed AH, Hegazy MF, et al. (2012). Euphorbia helioscopia: Chemical constituents and biological activities. International Journal of Phytopharmacology,2012,3(1),78-90. [View]
- Benabdelaziz I, Haba H, et al. (2015). Lignans and other constituents from Helianthemum sessiliflorum Pers.. Records of Natural Products,2015,9(3),342-348. [View]
- Pierre Yemback, Kenneth O. Eyong, et al. (2023). Lupane derivatives: Design, isolation, synthesis and evaluation of antiplasmodial activity against Plasmodium falciparum 3D7 strain. Phytochemistry Letters, 2023, 57, 26-35. [View]
- Askri M, Mighri Z, et al. (1989). Medicinal plants of Tunisia. the structure of periplocadiol, a new elemane-type sesquiterpene isolated from the roots of Periploca laevigata. Journal of Natural Products,1989,52(4),792-796. [View]
- Abdel-Gawad MM, El-Sayed MM and Abdel-Hameed ES. (1999). Molluscicidal steroidal saponins and lipid content of Agave decipiens. Fitoterapia,1999,70,371-381. [View]
- Ben Salem S, Jabrane A, et al. (2013). New bioactive dihydrofuranocoumarins from the roots of the Tunisian Ferula lutea (Poir.) Maire.. Bioorganic and Medicinal Chemistry Letters,2013,23(14),4248-4252. [View] [PubMed]
- Mohamed NM, Makboul MA, et al. (2015). New pentacyclic triterpenoid from the roots of Lantana montevidensis (spreng.) briq. cultivated in Egypt. Planta Medica,2015,81-PC22. [View]
- Mbaze LM, Lado JA, et al. (2009). Oxidative burst inhibitory and cytotoxic amides and lignans from the stem bark of Fagara heitzii (Rutaceae).. Phytochemistry,2009, 70(11-12), 1442-1447. [View] [PubMed]
- Abdel-Wahab NM, Hamed ANE, et al. (2014). Phenolic acid glycosides from Parmentiera cereifera Seem. (Candle tree). Phytochemistry Letters,2014,9,74-77. [View]
- ELhassan GOM, Adhikari A, et al. (2012). Phytochemistry and antiglycation activity of Aloe sinkatana Reynolds. Phytochemistry Letters,2012,5(4),725-728. [View]
- Eldahshan OA, Ayoub NA, et al. (2008). Potential superoxide anion radical scavenging activity of doum palm (Hyphaene thebaica L.) leaves extract. Records of Natural Products,2008,2(3),83-93. [View]
- Hassan HA, Hamed AI, et al. (2001). Pregnene derivatives from Solenostemma argel leaves. Phytochemistry,2001,57(4),507-511. [View] [PubMed]
- Abdallah HM, Ezzat SM, et al. (2013). Protective effect of Echinops galalensis against CCl4-induced injury on the human hepatoma cell line (Huh7). Phytochemistry Letters,2013,6,73-78. [View]
- El-Dib R, Kaloga M, et al. (2004). Sablacaurin A and B, two 19-nor-3,4-seco-lanostane-type triterpenoids from Sabal causiarum and Sabal blackburniana, respectively. Phytochemistry,2004,65(8),1153-1157. [View] [PubMed]
- Harkati B, Akkal S, et al. (2010). Secondary metabolites from Scorzonera undulata ssp. deliciosa (Guss.) Maire (Asteracae) and their antioxidant activities. Records of Natural Products,2010,4(3),171-175. [View]
- Abdel-Mogib M, Jakupovic J, et al. (1990). Sesquiterpene lactones and kaurane glycosides from Francoeuria crispa. Phytochemistry,1990,29(8),2581-2584. [View]
- Mahmoud ZF, Kassem FF, et al. (1986). Sesquiterpene lactones from Lactuca sativa. Phytochemistry,1986,25(3),141-748. [View]
- Chi GF, Sop RVT, et al. (2020). Steroidal saponins from Raphia vinifera and their cytotoxic activity. Steroids,2020, 163, 108724. [View] [PubMed]
- Aichour S, Haba H, et al. (2014). Terpenoids and other constituents from Euphorbia bupleuroides. Phytochemistry,2014,10,198-203. [View]
- Mahmoud Z, El-Masry S, et al. (1983). Two eudesmanolides from Sonchus macrocarpus. Phytochemistry,1983,22(5),1290-1291. [View]
- Mbarga P E, Fouotsa H, et al. (2023). Two new secondary metabolites with antibacterial activities from Conyza aegyptiaca (Asteraceae). Natural product research,2023, 37(11), 1806-1815. [View] [PubMed]
Pubchem:
222284
Cas:
83-46-5
Gnps:
CCMSLIB00000213190
Zinc:
ZINC000004095717
Kegg Ligand:
C01753
Chebi:
27693
Nmrshiftdb2:
60018437
Metabolights:
MTBLC27693
Chembl:
CHEMBL221542
Comptox:
DTXSID5022481
Drugbank:
DB14038
Bindingdb:
50218197
Selleck:
Beta-Sitosterol
CPRiL:
2378
SMILES: C1CCC(C12)CCC3C2CC=C4C3CCCC4
Level: 0
Mol. Weight: 414.72 g/mol
Antimicrobial
Antioxidant
Antiradical potential
Antitumor
Antiviral
Cytotoxic
Protective against ccl4-induced injury on the human hepatoma cell line (huh7)
Suppressive on phagocytosis response upon activation with serum
Absorption
- Caco-2 (logPapp)
- -4.96
- Human Oral Bioavailability 20%
- Bioavailable
- Human Intestinal Absorption
- Absorbed
- Madin-Darby Canine Kidney
- -4.44
- Human Oral Bioavailability 50%
- Bioavailable
- P-Glycoprotein Inhibitor
- Non-Inhibitor
- P-Glycoprotein Substrate
- Non-Substrate
- Skin Permeability
- -2.91
Distribution
- Blood-Brain Barrier (CNS)
- -
- Blood-Brain Barrier
- Penetrable
- Fraction Unbound (Human)
- 1.76
- Plasma Protein Binding
- 83.49
- Steady State Volume of Distribution
- -
Metabolism
- Breast Cancer Resistance Protein
- Non-Inhibitor
- CYP 1A2 Inhibitor
- Non-Inhibitor
- CYP 1A2 Substrate
- Non-Substrate
- CYP 2C19 Inhibitor
- Non-Inhibitor
- CYP 2C19 Substrate
- Substrate
- CYP 2C9 Inhibitor
- Non-Inhibitor
- CYP 2C9 Substrate
- Non-Substrate
- CYP 2D6 Inhibitor
- Non-Inhibitor
- CYP 2D6 Substrate
- Non-Substrate
- CYP 3A4 Inhibitor
- Non-Inhibitor
- CYP 3A4 Substrate
- Substrate
- OATP1B1
- Non-Inhibitor
- OATP1B3
- Non-Inhibitor
Excretion
- Clearance
- 10.95
- Organic Cation Transporter 2
- Non-Inhibitor
- Half-Life of Drug
- -
Toxicity
- AMES Mutagenesis
- Safe
- Avian
- Safe
- Bee
- Toxic
- Bioconcentration Factor
- 1.02
- Biodegradation
- Safe
- Carcinogenesis
- Safe
- Crustacean
- Toxic
- Liver Injury I (DILI)
- Safe
- Eye Corrosion
- Safe
- Eye Irritation
- Safe
- Maximum Tolerated Dose
- 2.07
- Liver Injury II
- Safe
- hERG Blockers
- Toxic
- Daphnia Maga
- 6.22
- Micronucleos
- Safe
- NR-AhR
- Safe
- NR-AR
- Toxic
- NR-AR-LBD
- Safe
- NR-Aromatase
- Safe
- NR-ER
- Safe
- NR-ER-LBD
- Safe
- NR-GR
- Safe
- NR-PPAR-gamma
- Safe
- NR-TR
- Safe
- T. Pyriformis
- -33.89
- Rat (Acute)
- 2.19
- Rat (Chronic Oral)
- 1.92
- Fathead Minnow
- 3.92
- Respiratory Disease
- Toxic
- Skin Sensitisation
- Toxic
- SR-ARE
- Safe
- SR-ATAD5
- Safe
- SR-HSE
- Safe
- SR-MMP
- Safe
- SR-p53
- Safe
General Properties
- Boiling Point
- 407.0
- Hydration Free Energy
- -3.84
- Log(D) at pH=7.4
- 6.64
- Log(P)
- 8.99
- Log S
- -6.92
- Log(Vapor Pressure)
- -7.25
- Melting Point
- 142.71
- pKa Acid
- 13.6
- pKa Basic
- 8.5
Protein Name | UniProt ID | Entry Name | Species | #Pharmacophore Points | Probability (0.7 ≤ Tversky Score ≤ 1.0) |
---|---|---|---|---|---|
Aldo-keto reductase family 1 member D1 | P51857 | AK1D1_HUMAN | Homo sapiens | 3 | 0.9594 |
Aldo-keto reductase family 1 member C2 | P52895 | AK1C2_HUMAN | Homo sapiens | 3 | 0.9500 |
Retinol-binding protein 1 | P02696 | RET1_RAT | Rattus norvegicus | 3 | 0.9465 |
3-alpha-hydroxysteroid dehydrogenase | P23457 | DIDH_RAT | Rattus norvegicus | 3 | 0.9455 |
17-beta-hydroxysteroid dehydrogenase type 1 | P14061 | DHB1_HUMAN | Homo sapiens | 3 | 0.9413 |
3-alpha-hydroxysteroid dehydrogenase | P23457 | DIDH_RAT | Rattus norvegicus | 3 | 0.9406 |
Aldo-keto reductase family 1 member D1 | P51857 | AK1D1_HUMAN | Homo sapiens | 3 | 0.9403 |
Aldo-keto reductase family 1 member D1 | P51857 | AK1D1_HUMAN | Homo sapiens | 3 | 0.9346 |
Steroid Delta-isomerase | P00947 | SDIS_COMTE | Comamonas testosteroni | 3 | 0.9288 |
Aldo-keto reductase family 1 member D1 | P51857 | AK1D1_HUMAN | Homo sapiens | 3 | 0.9288 |
Aldo-keto reductase family 1 member D1 | P51857 | AK1D1_HUMAN | Homo sapiens | 3 | 0.9237 |
Aldo-keto reductase family 1 member D1 | P51857 | AK1D1_HUMAN | Homo sapiens | 3 | 0.9199 |
Steroid Delta-isomerase | P00947 | SDIS_COMTE | Comamonas testosteroni | 3 | 0.9188 |
Aldo-keto reductase family 1 member D1 | P51857 | AK1D1_HUMAN | Homo sapiens | 3 | 0.9166 |
Aldo-keto reductase family 1 member C2 | P52895 | AK1C2_HUMAN | Homo sapiens | 3 | 0.9153 |
Aldo-keto reductase family 1 member D1 | P51857 | AK1D1_HUMAN | Homo sapiens | 3 | 0.9134 |
Aldo-keto reductase family 1 member D1 | P51857 | AK1D1_HUMAN | Homo sapiens | 3 | 0.9131 |
Aldo-keto reductase family 1 member D1 | P51857 | AK1D1_HUMAN | Homo sapiens | 3 | 0.9121 |
Steroid Delta-isomerase | P00947 | SDIS_COMTE | Comamonas testosteroni | 3 | 0.9114 |
Steroid Delta-isomerase | P00947 | SDIS_COMTE | Comamonas testosteroni | 3 | 0.9099 |
Aldo-keto reductase family 1 member D1 | P51857 | AK1D1_HUMAN | Homo sapiens | 3 | 0.9096 |
Aldo-keto reductase family 1 member D1 | P51857 | AK1D1_HUMAN | Homo sapiens | 3 | 0.9073 |
Aldo-keto reductase family 1 member D1 | P51857 | AK1D1_HUMAN | Homo sapiens | 3 | 0.9038 |
Steroid Delta-isomerase | P00947 | SDIS_COMTE | Comamonas testosteroni | 3 | 0.9012 |
Aldo-keto reductase family 1 member C2 | P52895 | AK1C2_HUMAN | Homo sapiens | 3 | 0.8955 |
Steroid Delta-isomerase | P07445 | SDIS_PSEPU | Pseudomonas putida | 3 | 0.8937 |
Aldo-keto reductase family 1 member D1 | P51857 | AK1D1_HUMAN | Homo sapiens | 3 | 0.8927 |
Aldo-keto reductase family 1 member D1 | P51857 | AK1D1_HUMAN | Homo sapiens | 3 | 0.8903 |
Aldo-keto reductase family 1 member D1 | P51857 | AK1D1_HUMAN | Homo sapiens | 3 | 0.8896 |
Oxysterols receptor LXR-beta | P55055 | NR1H2_HUMAN | Homo sapiens | 4 | 0.8752 |
Aldo-keto reductase family 1 member D1 | P51857 | AK1D1_HUMAN | Homo sapiens | 3 | 0.8697 |
Mycinamicin III 3''-O-methyltransferase | Q49492 | MYCF_MICGR | Micromonospora griseorubida | 2 | 0.8688 |
Steroid Delta-isomerase | P00947 | SDIS_COMTE | Comamonas testosteroni | 3 | 0.8627 |
Aldo-keto reductase family 1 member C2 | P52895 | AK1C2_HUMAN | Homo sapiens | 3 | 0.8613 |
Aldo-keto reductase family 1 member C2 | P52895 | AK1C2_HUMAN | Homo sapiens | 3 | 0.8610 |
Vitamin D(3) 25-hydroxylase | C4B644 | CPVDH_PSEAH | Pseudonocardia autotrophica | 3 | 0.8549 |
Aldo-keto reductase family 1 member D1 | P51857 | AK1D1_HUMAN | Homo sapiens | 3 | 0.8543 |
Steroid C26-monooxygenase | P9WPP1 | CP125_MYCTU | Mycobacterium tuberculosis | 3 | 0.8529 |
Steroid Delta-isomerase | P07445 | SDIS_PSEPU | Pseudomonas putida | 3 | 0.8308 |
Sulfotransferase 2B1 | O00204 | ST2B1_HUMAN | Homo sapiens | 3 | 0.8242 |
Retinol-binding protein 1 | P02696 | RET1_RAT | Rattus norvegicus | 3 | 0.8232 |
Nuclear receptor subfamily 1 group I member 3 | O35627 | NR1I3_MOUSE | Mus musculus | 3 | 0.8206 |
Nuclear receptor ROR-alpha | P35398 | RORA_HUMAN | Homo sapiens | 5 | 0.8193 |
Pentaerythritol tetranitrate reductase | P71278 | P71278_ENTCL | Enterobacter cloacae | 3 | 0.8191 |
Sex hormone-binding globulin | P04278 | SHBG_HUMAN | Homo sapiens | 3 | 0.8186 |
3-ketosteroid dehydrogenase | Q9RA02 | Q9RA02_RHOER | Rhodococcus erythropolis | 3 | 0.8181 |
Nuclear receptor ROR-alpha | P35398 | RORA_HUMAN | Homo sapiens | 5 | 0.8139 |
Japanin | M1MR49 | M1MR49_RHIAP | Rhipicephalus appendiculatus | 5 | 0.8075 |
17-beta-hydroxysteroid dehydrogenase type 1 | P14061 | DHB1_HUMAN | Homo sapiens | 3 | 0.8045 |
Fatty acid-binding protein, liver | P80226 | FABPL_CHICK | Gallus gallus | 3 | 0.8013 |
Cholesterol side-chain cleavage enzyme, mitochondrial | P05108 | CP11A_HUMAN | Homo sapiens | 3 | 0.8009 |
Sulfotransferase 2B1 | O00204 | ST2B1_HUMAN | Homo sapiens | 3 | 0.8002 |
Beta-lactoglobulin | P02754 | LACB_BOVIN | Bos taurus | 3 | 0.7957 |
Mycinamicin III 3''-O-methyltransferase | Q49492 | MYCF_MICGR | Micromonospora griseorubida | 2 | 0.7921 |
Beta-elicitin cryptogein | P15570 | ELIB_PHYCR | Phytophthora cryptogea | 4 | 0.7881 |
Soluble acetylcholine receptor | Q8WSF8 | Q8WSF8_APLCA | Aplysia californica | 3 | 0.7838 |
Lanosterol 14-alpha-demethylase | Q385E8 | Q385E8_TRYB2 | Trypanosoma brucei brucei | 4 | 0.7774 |
Protein BRASSINOSTEROID INSENSITIVE 1 | O22476 | BRI1_ARATH | Arabidopsis thaliana | 3 | 0.7748 |
Soluble acetylcholine receptor | Q8WSF8 | Q8WSF8_APLCA | Aplysia californica | 3 | 0.7650 |
Enoyl-[acyl-carrier-protein] reductase [NADH] | P9WGR1 | INHA_MYCTU | Mycobacterium tuberculosis | 3 | 0.7645 |
11-beta-hydroxysteroid dehydrogenase 1 | P50172 | DHI1_MOUSE | Mus musculus | 3 | 0.7623 |
Ferrochelatase, mitochondrial | P22830 | HEMH_HUMAN | Homo sapiens | 3 | 0.7620 |
Japanin | M1MR49 | M1MR49_RHIAP | Rhipicephalus appendiculatus | 5 | 0.7616 |
Protein BRASSINOSTEROID INSENSITIVE 1 | O22476 | BRI1_ARATH | Arabidopsis thaliana | 3 | 0.7571 |
Progesterone receptor | P06401 | PRGR_HUMAN | Homo sapiens | 3 | 0.7509 |
Mycinamicin III 3''-O-methyltransferase | Q49492 | MYCF_MICGR | Micromonospora griseorubida | 2 | 0.7503 |
Oxysterols receptor LXR-beta | P55055 | NR1H2_HUMAN | Homo sapiens | 4 | 0.7499 |
Ferrochelatase, mitochondrial | P22830 | HEMH_HUMAN | Homo sapiens | 3 | 0.7473 |
Alcohol dehydrogenase 1C | P00326 | ADH1G_HUMAN | Homo sapiens | 3 | 0.7458 |
Probable NDP-rhamnosyltransferase | Q9ALM8 | Q9ALM8_SACSN | Saccharopolyspora spinosa | 3 | 0.7455 |
Sex hormone-binding globulin | P04278 | SHBG_HUMAN | Homo sapiens | 3 | 0.7445 |
CmeR | Q7B8P6 | Q7B8P6_CAMJU | Campylobacter jejuni | 2 | 0.7444 |
Retinoic acid receptor RXR-alpha | P19793 | RXRA_HUMAN | Homo sapiens | 3 | 0.7433 |
Retinol dehydratase | Q26490 | Q26490_SPOFR | Spodoptera frugiperda | 3 | 0.7408 |
Fatty acid-binding protein, liver | P80226 | FABPL_CHICK | Gallus gallus | 3 | 0.7407 |
Protein BRASSINOSTEROID INSENSITIVE 1 | O22476 | BRI1_ARATH | Arabidopsis thaliana | 3 | 0.7406 |
Steroid C26-monooxygenase | P9WPP1 | CP125_MYCTU | Mycobacterium tuberculosis | 3 | 0.7393 |
Aldo-keto reductase family 1 member C1 | Q04828 | AK1C1_HUMAN | Homo sapiens | 3 | 0.7361 |
NPC intracellular cholesterol transporter 1 | O15118 | NPC1_HUMAN | Homo sapiens | 3 | 0.7356 |
Type IV / VI secretion system DotU domain-containing protein | Q9KN50 | Q9KN50_VIBCH | Vibrio cholerae serotype O1 | 2 | 0.7343 |
Aldo-keto reductase family 1 member C2 | P52895 | AK1C2_HUMAN | Homo sapiens | 3 | 0.7333 |
Gastrotropin | P51161 | FABP6_HUMAN | Homo sapiens | 3 | 0.7271 |
Type IV / VI secretion system DotU domain-containing protein | Q9KN50 | Q9KN50_VIBCH | Vibrio cholerae serotype O1 | 2 | 0.7257 |
Retinoic acid receptor RXR-alpha | P19793 | RXRA_HUMAN | Homo sapiens | 3 | 0.7250 |
Nuclear receptor ROR-gamma | P51449 | RORG_HUMAN | Homo sapiens | 4 | 0.7245 |
Progesterone receptor | P06401 | PRGR_HUMAN | Homo sapiens | 3 | 0.7244 |
Progesterone receptor | P06401 | PRGR_HUMAN | Homo sapiens | 3 | 0.7235 |
Aldo-keto reductase family 1 member D1 | P51857 | AK1D1_HUMAN | Homo sapiens | 3 | 0.7230 |
Protein BRASSINOSTEROID INSENSITIVE 1 | O22476 | BRI1_ARATH | Arabidopsis thaliana | 3 | 0.7226 |
Beta-lactoglobulin | P02754 | LACB_BOVIN | Bos taurus | 3 | 0.7209 |
Aldo-keto reductase family 1 member D1 | P51857 | AK1D1_HUMAN | Homo sapiens | 3 | 0.7189 |
ADP-ribosylation factor 1 | P84080 | ARF1_BOVIN | Bos taurus | 3 | 0.7159 |
Sulfotransferase 2B1 | O00204 | ST2B1_HUMAN | Homo sapiens | 3 | 0.7114 |
Beta-1 adrenergic receptor | P07700 | ADRB1_MELGA | Meleagris gallopavo | 3 | 0.7107 |
Beta-1 adrenergic receptor | P07700 | ADRB1_MELGA | Meleagris gallopavo | 2 | 0.7103 |
Enoyl-[acyl-carrier-protein] reductase [NADH] | P9WGR1 | INHA_MYCTU | Mycobacterium tuberculosis | 3 | 0.7099 |
Apocarotenoid-15,15'-oxygenase | P74334 | ACOX_SYNY3 | Synechocystis sp | 5 | 0.7089 |
Beta-1 adrenergic receptor | P07700 | ADRB1_MELGA | Meleagris gallopavo | 3 | 0.7069 |
Ferrochelatase, mitochondrial | P22830 | HEMH_HUMAN | Homo sapiens | 3 | 0.7063 |
Liver carboxylesterase 1 | P23141 | EST1_HUMAN | Homo sapiens | 2 | 0.7045 |
Photosynthetic reaction center cytochrome c subunit | P07173 | CYCR_BLAVI | Blastochloris viridis | 3 | 0.7003 |