Select a section from the left sidebar
Olibanumol C
- Family: Plantae - Burseraceae
- Kingdom: Plantae
-
Class: Terpenoid
- Subclass: Monoterpene
| Canonical Smiles | OCC1=CC[C@@](CC1)(O)C(C)C |
|---|---|
| InChI | InChI=1S/C10H18O2/c1-8(2)10(12)5-3-9(7-11)4-6-10/h3,8,11-12H,4-7H2,1-2H3/t10-/m0/s1 |
| InChIKey | GSEDQEXTVARKJC-JTQLQIEISA-N |
| Formula | C10H18O2 |
| HBA | 2 |
| HBD | 2 |
| MW | 170.25 |
| Rotatable Bonds | 2 |
| TPSA | 40.46 |
| LogP | 1.48 |
| Number Rings | 1 |
| Number Aromatic Rings | 0 |
| Heavy Atom Count | 12 |
| Formal Charge | 0 |
| Fraction CSP3 | 0.8 |
| Exact Mass | 170.13 |
| Number of Lipinski Rule Violations | 0 |
| # | Species | Family | Kingdom | NCBI Taxonomy ID |
|---|---|---|---|---|
| 1 | Boswellia carterii | Burseraceae | Plantae | 80276 |
Showing of synonyms
Olibanumol C
- Yoshikawa M, Morikawa T, et al. (2009). Absolute stereostructures of olibanumols A, B, C, H, I, and J from olibanum, gum-resin of Boswellia carterii, and inhibitors of nitric oxide production in lipopolysaccharide-activated mouse peritoneal macrophages. Chemical and Pharmaceutical Bulletin,2009,57(9),957-964. [View] [PubMed]
No compound-protein relationship available.
SMILES: C1=CCCCC1
Level: 0
Mol. Weight: 170.25 g/mol
No bioactivities available.
Absorption
- Caco-2 (logPapp)
- -4.82
- Human Oral Bioavailability 20%
- Bioavailable
- Human Intestinal Absorption
- Absorbed
- Madin-Darby Canine Kidney
- -3.67
- Human Oral Bioavailability 50%
- Bioavailable
- P-Glycoprotein Inhibitor
- Non-Inhibitor
- P-Glycoprotein Substrate
- Non-Substrate
- Skin Permeability
- -2.88
Distribution
- Blood-Brain Barrier (CNS)
- -
- Blood-Brain Barrier
- Penetrable
- Fraction Unbound (Human)
- 0.18
- Plasma Protein Binding
- 20.21
- Steady State Volume of Distribution
- -
Metabolism
- Breast Cancer Resistance Protein
- Non-Inhibitor
- CYP 1A2 Inhibitor
- Non-Inhibitor
- CYP 1A2 Substrate
- Non-Substrate
- CYP 2C19 Inhibitor
- Non-Inhibitor
- CYP 2C19 Substrate
- Non-Substrate
- CYP 2C9 Inhibitor
- Non-Inhibitor
- CYP 2C9 Substrate
- Non-Substrate
- CYP 2D6 Inhibitor
- Non-Inhibitor
- CYP 2D6 Substrate
- Substrate
- CYP 3A4 Inhibitor
- Non-Inhibitor
- CYP 3A4 Substrate
- Non-Substrate
- OATP1B1
- Non-Inhibitor
- OATP1B3
- Non-Inhibitor
Excretion
- Clearance
- 7.64
- Organic Cation Transporter 2
- Non-Inhibitor
- Half-Life of Drug
- -
Toxicity
- AMES Mutagenesis
- Safe
- Avian
- Safe
- Bee
- Toxic
- Bioconcentration Factor
- 0.61
- Biodegradation
- Safe
- Carcinogenesis
- Safe
- Crustacean
- Safe
- Liver Injury I (DILI)
- Safe
- Eye Corrosion
- Safe
- Eye Irritation
- Toxic
- Maximum Tolerated Dose
- 1.09
- Liver Injury II
- Safe
- hERG Blockers
- Safe
- Daphnia Maga
- 3.19
- Micronucleos
- Safe
- NR-AhR
- Safe
- NR-AR
- Safe
- NR-AR-LBD
- Safe
- NR-Aromatase
- Safe
- NR-ER
- Safe
- NR-ER-LBD
- Safe
- NR-GR
- Safe
- NR-PPAR-gamma
- Safe
- NR-TR
- Safe
- T. Pyriformis
- -0.55
- Rat (Acute)
- 1.81
- Rat (Chronic Oral)
- 1.91
- Fathead Minnow
- 3.3
- Respiratory Disease
- Safe
- Skin Sensitisation
- Toxic
- SR-ARE
- Safe
- SR-ATAD5
- Safe
- SR-HSE
- Safe
- SR-MMP
- Safe
- SR-p53
- Safe
General Properties
- Boiling Point
- 262.52
- Hydration Free Energy
- -8.05
- Log(D) at pH=7.4
- 0.64
- Log(P)
- 1.61
- Log S
- -0.8
- Log(Vapor Pressure)
- -2.84
- Melting Point
- 86.7
- pKa Acid
- 11.26
- pKa Basic
- 7.63
| Protein Name | UniProt ID | Entry Name | Species | #Pharmacophore Points | Probability (0.7 ≤ Tversky Score ≤ 1.0) |
|---|---|---|---|---|---|
| Retinoic acid receptor RXR-alpha | P19793 | RXRA_HUMAN | Homo sapiens | 3 | 0.9644 |
| Retinoic acid receptor RXR-alpha | P19793 | RXRA_HUMAN | Homo sapiens | 3 | 0.9644 |
| Aromatase | P11511 | CP19A_HUMAN | Homo sapiens | 3 | 0.9633 |
| Aromatase | P11511 | CP19A_HUMAN | Homo sapiens | 3 | 0.9633 |
| Sulfotransferase 2B1 | O00204 | ST2B1_HUMAN | Homo sapiens | 3 | 0.9608 |
| Sulfotransferase 2B1 | O00204 | ST2B1_HUMAN | Homo sapiens | 3 | 0.9608 |
| Sulfotransferase 2A1 | Q06520 | ST2A1_HUMAN | Homo sapiens | 3 | 0.9519 |
| Sulfotransferase 2A1 | Q06520 | ST2A1_HUMAN | Homo sapiens | 3 | 0.9519 |
| Cytochrome P450 monooxygenase | Q5YNS8 | Q5YNS8_NOCFA | Nocardia farcinica | 3 | 0.9481 |
| Cytochrome P450 monooxygenase | Q5YNS8 | Q5YNS8_NOCFA | Nocardia farcinica | 3 | 0.9481 |
| Sulfotransferase 2A1 | Q06520 | ST2A1_HUMAN | Homo sapiens | 3 | 0.9393 |
| Sulfotransferase 2A1 | Q06520 | ST2A1_HUMAN | Homo sapiens | 3 | 0.9393 |
| Corticosteroid-binding globulin | P08185 | CBG_HUMAN | Homo sapiens | 3 | 0.9391 |
| Corticosteroid-binding globulin | P08185 | CBG_HUMAN | Homo sapiens | 3 | 0.9391 |
| Aldo-keto reductase family 1 member C2 | P52895 | AK1C2_HUMAN | Homo sapiens | 3 | 0.9348 |
| Aldo-keto reductase family 1 member C2 | P52895 | AK1C2_HUMAN | Homo sapiens | 3 | 0.9348 |
| Androgen receptor | P10275 | ANDR_HUMAN | Homo sapiens | 3 | 0.9331 |
| Androgen receptor | P10275 | ANDR_HUMAN | Homo sapiens | 3 | 0.9331 |
| Aldo-keto reductase family 1 member D1 | P51857 | AK1D1_HUMAN | Homo sapiens | 3 | 0.9300 |
| Aldo-keto reductase family 1 member D1 | P51857 | AK1D1_HUMAN | Homo sapiens | 3 | 0.9300 |
| Androgen receptor | P10275 | ANDR_HUMAN | Homo sapiens | 3 | 0.9278 |
| Androgen receptor | P10275 | ANDR_HUMAN | Homo sapiens | 3 | 0.9278 |
| Aldo-keto reductase family 1 member C2 | P52895 | AK1C2_HUMAN | Homo sapiens | 3 | 0.9233 |
| Aldo-keto reductase family 1 member C2 | P52895 | AK1C2_HUMAN | Homo sapiens | 3 | 0.9233 |
| Soluble cytochrome b562 | P0ABE7 | C562_ECOLX | Escherichia coli | 3 | 0.9208 |
| Soluble cytochrome b562 | P0ABE7 | C562_ECOLX | Escherichia coli | 3 | 0.9208 |
| Cytochrome P450 monooxygenase | Q5YNS8 | Q5YNS8_NOCFA | Nocardia farcinica | 3 | 0.9105 |
| Cytochrome P450 monooxygenase | Q5YNS8 | Q5YNS8_NOCFA | Nocardia farcinica | 3 | 0.9105 |
| 17-beta-hydroxysteroid dehydrogenase type 1 | P14061 | DHB1_HUMAN | Homo sapiens | 3 | 0.9029 |
| 17-beta-hydroxysteroid dehydrogenase type 1 | P14061 | DHB1_HUMAN | Homo sapiens | 3 | 0.9029 |
| Gastrotropin | Q6IMW5 | Q6IMW5_DANRE | Danio rerio | 3 | 0.9027 |
| Gastrotropin | Q6IMW5 | Q6IMW5_DANRE | Danio rerio | 3 | 0.9027 |
| 17-beta-hydroxysteroid dehydrogenase type 1 | P14061 | DHB1_HUMAN | Homo sapiens | 3 | 0.8934 |
| 17-beta-hydroxysteroid dehydrogenase type 1 | P14061 | DHB1_HUMAN | Homo sapiens | 3 | 0.8934 |
| Steroid Delta-isomerase | P07445 | SDIS_PSEPU | Pseudomonas putida | 3 | 0.8874 |
| Steroid Delta-isomerase | P07445 | SDIS_PSEPU | Pseudomonas putida | 3 | 0.8874 |
| Steroid Delta-isomerase | P00947 | SDIS_COMTE | Comamonas testosteroni | 3 | 0.8711 |
| Steroid Delta-isomerase | P00947 | SDIS_COMTE | Comamonas testosteroni | 3 | 0.8711 |
| Steroid Delta-isomerase | P00947 | SDIS_COMTE | Comamonas testosteroni | 3 | 0.8634 |
| Steroid Delta-isomerase | P00947 | SDIS_COMTE | Comamonas testosteroni | 3 | 0.8634 |
| CmeR | Q7B8P6 | Q7B8P6_CAMJU | Campylobacter jejuni | 3 | 0.8620 |
| CmeR | Q7B8P6 | Q7B8P6_CAMJU | Campylobacter jejuni | 3 | 0.8620 |
| Aldo-keto reductase family 1 member D1 | P51857 | AK1D1_HUMAN | Homo sapiens | 3 | 0.8611 |
| Aldo-keto reductase family 1 member D1 | P51857 | AK1D1_HUMAN | Homo sapiens | 3 | 0.8611 |
| Aldo-keto reductase family 1 member D1 | P51857 | AK1D1_HUMAN | Homo sapiens | 3 | 0.8558 |
| Aldo-keto reductase family 1 member D1 | P51857 | AK1D1_HUMAN | Homo sapiens | 3 | 0.8558 |
| Aldo-keto reductase family 1 member D1 | P51857 | AK1D1_HUMAN | Homo sapiens | 3 | 0.8509 |
| Aldo-keto reductase family 1 member D1 | P51857 | AK1D1_HUMAN | Homo sapiens | 3 | 0.8509 |
| Sulfotransferase 2B1 | O00204 | ST2B1_HUMAN | Homo sapiens | 2 | 0.8504 |
| Sulfotransferase 2B1 | O00204 | ST2B1_HUMAN | Homo sapiens | 2 | 0.8504 |
| 3-alpha-hydroxysteroid dehydrogenase | P23457 | DIDH_RAT | Rattus norvegicus | 3 | 0.8480 |
| 3-alpha-hydroxysteroid dehydrogenase | P23457 | DIDH_RAT | Rattus norvegicus | 3 | 0.8480 |
| Sex hormone-binding globulin | P04278 | SHBG_HUMAN | Homo sapiens | 3 | 0.8457 |
| Sex hormone-binding globulin | P04278 | SHBG_HUMAN | Homo sapiens | 3 | 0.8457 |
| Photosynthetic reaction center cytochrome c subunit | P07173 | CYCR_BLAVI | Blastochloris viridis | 3 | 0.8416 |
| Photosynthetic reaction center cytochrome c subunit | P07173 | CYCR_BLAVI | Blastochloris viridis | 3 | 0.8416 |
| Aldo-keto reductase family 1 member D1 | P51857 | AK1D1_HUMAN | Homo sapiens | 3 | 0.8405 |
| Aldo-keto reductase family 1 member D1 | P51857 | AK1D1_HUMAN | Homo sapiens | 3 | 0.8405 |
| Aldo-keto reductase family 1 member D1 | P51857 | AK1D1_HUMAN | Homo sapiens | 3 | 0.8295 |
| Aldo-keto reductase family 1 member D1 | P51857 | AK1D1_HUMAN | Homo sapiens | 3 | 0.8295 |
| Steroid 21-hydroxylase | P08686 | CP21A_HUMAN | Homo sapiens | 3 | 0.8282 |
| Steroid 21-hydroxylase | P08686 | CP21A_HUMAN | Homo sapiens | 3 | 0.8282 |
| ADP-ribosylation factor 1 | P84080 | ARF1_BOVIN | Bos taurus | 3 | 0.8089 |
| ADP-ribosylation factor 1 | P84080 | ARF1_BOVIN | Bos taurus | 3 | 0.8089 |
| Photosynthetic reaction center cytochrome c subunit | P07173 | CYCR_BLAVI | Blastochloris viridis | 3 | 0.8078 |
| Photosynthetic reaction center cytochrome c subunit | P07173 | CYCR_BLAVI | Blastochloris viridis | 3 | 0.8078 |
| Aldo-keto reductase family 1 member D1 | P51857 | AK1D1_HUMAN | Homo sapiens | 3 | 0.8043 |
| Aromatase | P11511 | CP19A_HUMAN | Homo sapiens | 3 | 0.8043 |
| Aromatase | P11511 | CP19A_HUMAN | Homo sapiens | 3 | 0.8043 |
| Aldo-keto reductase family 1 member D1 | P51857 | AK1D1_HUMAN | Homo sapiens | 3 | 0.8043 |
| Ferrochelatase, mitochondrial | P22830 | HEMH_HUMAN | Homo sapiens | 2 | 0.7923 |
| Methylketone synthase I | E0YCS2 | E0YCS2_SOLHA | Solanum habrochaites | 2 | 0.7923 |
| Methylketone synthase I | E0YCS2 | E0YCS2_SOLHA | Solanum habrochaites | 2 | 0.7923 |
| Ferrochelatase, mitochondrial | P22830 | HEMH_HUMAN | Homo sapiens | 2 | 0.7923 |
| Lactoylglutathione lyase | Q9CPU0 | LGUL_MOUSE | Mus musculus | 2 | 0.7896 |
| Lactoylglutathione lyase | Q9CPU0 | LGUL_MOUSE | Mus musculus | 2 | 0.7896 |
| Aldo-keto reductase family 1 member C2 | P52895 | AK1C2_HUMAN | Homo sapiens | 2 | 0.7876 |
| Aldo-keto reductase family 1 member C2 | P52895 | AK1C2_HUMAN | Homo sapiens | 2 | 0.7876 |
| Sulfotransferase 2A1 | Q06520 | ST2A1_HUMAN | Homo sapiens | 3 | 0.7858 |
| Sulfotransferase 2A1 | Q06520 | ST2A1_HUMAN | Homo sapiens | 3 | 0.7858 |
| Aldo-keto reductase family 1 member C2 | P52895 | AK1C2_HUMAN | Homo sapiens | 2 | 0.7848 |
| Aldo-keto reductase family 1 member C2 | P52895 | AK1C2_HUMAN | Homo sapiens | 2 | 0.7848 |
| ADP-ribosylation factor 1 | P84080 | ARF1_BOVIN | Bos taurus | 3 | 0.7847 |
| ADP-ribosylation factor 1 | P84080 | ARF1_BOVIN | Bos taurus | 3 | 0.7847 |
| Prolyl tripeptidyl peptidase | Q7MUW6 | PTP_PORGI | Porphyromonas gingivalis | 3 | 0.7843 |
| Prolyl tripeptidyl peptidase | Q7MUW6 | PTP_PORGI | Porphyromonas gingivalis | 3 | 0.7843 |
| Androgen receptor | P10275 | ANDR_HUMAN | Homo sapiens | 3 | 0.7841 |
| Androgen receptor | P10275 | ANDR_HUMAN | Homo sapiens | 3 | 0.7841 |
| Androgen receptor | P10275 | ANDR_HUMAN | Homo sapiens | 3 | 0.7834 |
| Androgen receptor | P10275 | ANDR_HUMAN | Homo sapiens | 3 | 0.7834 |
| ADP-ribosylation factor 1 | P84077 | ARF1_HUMAN | Homo sapiens | 2 | 0.7827 |
| ADP-ribosylation factor 1 | P84077 | ARF1_HUMAN | Homo sapiens | 2 | 0.7827 |
| Androgen receptor | P10275 | ANDR_HUMAN | Homo sapiens | 3 | 0.7800 |
| Androgen receptor | P10275 | ANDR_HUMAN | Homo sapiens | 3 | 0.7800 |
| Fatty acid-binding protein, liver | P80226 | FABPL_CHICK | Gallus gallus | 2 | 0.7796 |
| Fatty acid-binding protein, liver | P80226 | FABPL_CHICK | Gallus gallus | 2 | 0.7796 |
| Progesterone receptor | P06401 | PRGR_HUMAN | Homo sapiens | 3 | 0.7791 |
| Progesterone receptor | P06401 | PRGR_HUMAN | Homo sapiens | 3 | 0.7791 |
| Androgen receptor | P10275 | ANDR_HUMAN | Homo sapiens | 3 | 0.7786 |
| Androgen receptor | P10275 | ANDR_HUMAN | Homo sapiens | 3 | 0.7786 |
| Androgen receptor | O97775 | ANDR_PANTR | Pan troglodytes | 3 | 0.7780 |
| Androgen receptor | P10275 | ANDR_HUMAN | Homo sapiens | 3 | 0.7780 |
| Androgen receptor | P10275 | ANDR_HUMAN | Homo sapiens | 3 | 0.7780 |
| Androgen receptor | O97775 | ANDR_PANTR | Pan troglodytes | 3 | 0.7780 |
| Photosynthetic reaction center cytochrome c subunit | P07173 | CYCR_BLAVI | Blastochloris viridis | 3 | 0.7760 |
| Photosynthetic reaction center cytochrome c subunit | P07173 | CYCR_BLAVI | Blastochloris viridis | 3 | 0.7760 |
| Androgen receptor | P10275 | ANDR_HUMAN | Homo sapiens | 3 | 0.7757 |
| Androgen receptor | P10275 | ANDR_HUMAN | Homo sapiens | 3 | 0.7757 |
| Androgen receptor | P10275 | ANDR_HUMAN | Homo sapiens | 3 | 0.7754 |
| Androgen receptor | P10275 | ANDR_HUMAN | Homo sapiens | 3 | 0.7754 |
| Androgen receptor | P10275 | ANDR_HUMAN | Homo sapiens | 3 | 0.7751 |
| Androgen receptor | P10275 | ANDR_HUMAN | Homo sapiens | 3 | 0.7751 |
| Androgen receptor | O97775 | ANDR_PANTR | Pan troglodytes | 3 | 0.7750 |
| Androgen receptor | O97775 | ANDR_PANTR | Pan troglodytes | 3 | 0.7750 |
| Androgen receptor | O97775 | ANDR_PANTR | Pan troglodytes | 3 | 0.7750 |
| Androgen receptor | O97775 | ANDR_PANTR | Pan troglodytes | 3 | 0.7750 |
| Androgen receptor | P10275 | ANDR_HUMAN | Homo sapiens | 3 | 0.7746 |
| Androgen receptor | P10275 | ANDR_HUMAN | Homo sapiens | 3 | 0.7746 |
| Androgen receptor | P10275 | ANDR_HUMAN | Homo sapiens | 3 | 0.7746 |
| Androgen receptor | P10275 | ANDR_HUMAN | Homo sapiens | 3 | 0.7746 |
| Androgen receptor | P10275 | ANDR_HUMAN | Homo sapiens | 3 | 0.7743 |
| 11-beta-hydroxysteroid dehydrogenase 1 | P28845 | DHI1_HUMAN | Homo sapiens | 3 | 0.7743 |
| Androgen receptor | P10275 | ANDR_HUMAN | Homo sapiens | 3 | 0.7743 |
| 11-beta-hydroxysteroid dehydrogenase 1 | P28845 | DHI1_HUMAN | Homo sapiens | 3 | 0.7743 |
| Androgen receptor | P10275 | ANDR_HUMAN | Homo sapiens | 3 | 0.7741 |
| Androgen receptor | P10275 | ANDR_HUMAN | Homo sapiens | 3 | 0.7741 |
| Androgen receptor | P10275 | ANDR_HUMAN | Homo sapiens | 3 | 0.7740 |
| Androgen receptor | P10275 | ANDR_HUMAN | Homo sapiens | 3 | 0.7740 |
| Androgen receptor | P10275 | ANDR_HUMAN | Homo sapiens | 3 | 0.7737 |
| Androgen receptor | P10275 | ANDR_HUMAN | Homo sapiens | 3 | 0.7737 |
| Alcohol dehydrogenase 1C | P00326 | ADH1G_HUMAN | Homo sapiens | 3 | 0.7734 |
| Alcohol dehydrogenase 1C | P00326 | ADH1G_HUMAN | Homo sapiens | 3 | 0.7734 |
| Androgen receptor | P19091 | ANDR_MOUSE | Mus musculus | 3 | 0.7734 |
| Androgen receptor | P19091 | ANDR_MOUSE | Mus musculus | 3 | 0.7734 |
| Nuclear receptor ROR-gamma | P51449 | RORG_HUMAN | Homo sapiens | 2 | 0.7726 |
| Nuclear receptor ROR-gamma | P51449 | RORG_HUMAN | Homo sapiens | 2 | 0.7726 |
| Androgen receptor | O97775 | ANDR_PANTR | Pan troglodytes | 3 | 0.7720 |
| Androgen receptor | O97775 | ANDR_PANTR | Pan troglodytes | 3 | 0.7720 |
| Androgen receptor | P10275 | ANDR_HUMAN | Homo sapiens | 3 | 0.7718 |
| Androgen receptor | P10275 | ANDR_HUMAN | Homo sapiens | 3 | 0.7718 |
| Androgen receptor | P10275 | ANDR_HUMAN | Homo sapiens | 3 | 0.7704 |
| Androgen receptor | P10275 | ANDR_HUMAN | Homo sapiens | 3 | 0.7704 |
| Androgen receptor | P10275 | ANDR_HUMAN | Homo sapiens | 3 | 0.7704 |
| Androgen receptor | P10275 | ANDR_HUMAN | Homo sapiens | 3 | 0.7704 |
| Androgen receptor | P10275 | ANDR_HUMAN | Homo sapiens | 3 | 0.7702 |
| Androgen receptor | P10275 | ANDR_HUMAN | Homo sapiens | 3 | 0.7702 |
| Androgen receptor | P10275 | ANDR_HUMAN | Homo sapiens | 3 | 0.7700 |
| Androgen receptor | P10275 | ANDR_HUMAN | Homo sapiens | 3 | 0.7700 |
| Androgen receptor | P10275 | ANDR_HUMAN | Homo sapiens | 3 | 0.7700 |
| Androgen receptor | P10275 | ANDR_HUMAN | Homo sapiens | 3 | 0.7700 |
| Androgen receptor | P10275 | ANDR_HUMAN | Homo sapiens | 3 | 0.7681 |
| Androgen receptor | P10275 | ANDR_HUMAN | Homo sapiens | 3 | 0.7681 |
| Androgen receptor | P10275 | ANDR_HUMAN | Homo sapiens | 3 | 0.7678 |
| Androgen receptor | P10275 | ANDR_HUMAN | Homo sapiens | 3 | 0.7678 |
| Sex hormone-binding globulin | P04278 | SHBG_HUMAN | Homo sapiens | 3 | 0.7671 |
| Sex hormone-binding globulin | P04278 | SHBG_HUMAN | Homo sapiens | 3 | 0.7671 |
| Androgen receptor | P10275 | ANDR_HUMAN | Homo sapiens | 3 | 0.7669 |
| Androgen receptor | P10275 | ANDR_HUMAN | Homo sapiens | 3 | 0.7669 |
| 11-beta-hydroxysteroid dehydrogenase 1 | P50172 | DHI1_MOUSE | Mus musculus | 2 | 0.7664 |
| 11-beta-hydroxysteroid dehydrogenase 1 | P50172 | DHI1_MOUSE | Mus musculus | 2 | 0.7664 |
| Androgen receptor | P10275 | ANDR_HUMAN | Homo sapiens | 3 | 0.7663 |
| Androgen receptor | P10275 | ANDR_HUMAN | Homo sapiens | 3 | 0.7663 |
| Trichothecene 15-O-acetyltransferase TRI3 | Q9C1B7 | TRI3_FUSSP | Fusarium sporotrichioides | 3 | 0.7662 |
| Trichothecene 15-O-acetyltransferase TRI3 | Q9C1B7 | TRI3_FUSSP | Fusarium sporotrichioides | 3 | 0.7662 |
| Aldo-keto reductase family 1 member D1 | P51857 | AK1D1_HUMAN | Homo sapiens | 3 | 0.7657 |
| Aldo-keto reductase family 1 member D1 | P51857 | AK1D1_HUMAN | Homo sapiens | 3 | 0.7657 |
| Androgen receptor | P10275 | ANDR_HUMAN | Homo sapiens | 3 | 0.7653 |
| Androgen receptor | P10275 | ANDR_HUMAN | Homo sapiens | 3 | 0.7653 |
| CmeR | Q7B8P6 | Q7B8P6_CAMJU | Campylobacter jejuni | 2 | 0.7648 |
| CmeR | Q7B8P6 | Q7B8P6_CAMJU | Campylobacter jejuni | 2 | 0.7648 |
| Androgen receptor | O97775 | ANDR_PANTR | Pan troglodytes | 3 | 0.7645 |
| Androgen receptor | O97775 | ANDR_PANTR | Pan troglodytes | 3 | 0.7645 |
| Androgen receptor | P10275 | ANDR_HUMAN | Homo sapiens | 3 | 0.7644 |
| Androgen receptor | P10275 | ANDR_HUMAN | Homo sapiens | 3 | 0.7644 |
| Aldo-keto reductase family 1 member D1 | P51857 | AK1D1_HUMAN | Homo sapiens | 2 | 0.7643 |
| Aldo-keto reductase family 1 member D1 | P51857 | AK1D1_HUMAN | Homo sapiens | 2 | 0.7643 |
| Aldo-keto reductase family 1 member D1 | P51857 | AK1D1_HUMAN | Homo sapiens | 2 | 0.7641 |
| Aldo-keto reductase family 1 member D1 | P51857 | AK1D1_HUMAN | Homo sapiens | 2 | 0.7641 |
| Retinol dehydratase | Q26490 | Q26490_SPOFR | Spodoptera frugiperda | 3 | 0.7640 |
| Retinol dehydratase | Q26490 | Q26490_SPOFR | Spodoptera frugiperda | 3 | 0.7640 |
| Androgen receptor | P10275 | ANDR_HUMAN | Homo sapiens | 3 | 0.7636 |
| Androgen receptor | P10275 | ANDR_HUMAN | Homo sapiens | 3 | 0.7636 |
| Androgen receptor | O97775 | ANDR_PANTR | Pan troglodytes | 3 | 0.7633 |
| Androgen receptor | O97775 | ANDR_PANTR | Pan troglodytes | 3 | 0.7633 |
| Androgen receptor | O97775 | ANDR_PANTR | Pan troglodytes | 3 | 0.7619 |
| Androgen receptor | O97775 | ANDR_PANTR | Pan troglodytes | 3 | 0.7619 |
| Androgen receptor | O97775 | ANDR_PANTR | Pan troglodytes | 3 | 0.7608 |
| Androgen receptor | O97775 | ANDR_PANTR | Pan troglodytes | 3 | 0.7608 |
| Androgen receptor | P10275 | ANDR_HUMAN | Homo sapiens | 3 | 0.7601 |
| Androgen receptor | P10275 | ANDR_HUMAN | Homo sapiens | 3 | 0.7601 |
| Aldo-keto reductase family 1 member C2 | P52895 | AK1C2_HUMAN | Homo sapiens | 2 | 0.7592 |
| Aldo-keto reductase family 1 member C2 | P52895 | AK1C2_HUMAN | Homo sapiens | 2 | 0.7592 |
| Prostaglandin reductase 2 | Q8N8N7 | PTGR2_HUMAN | Homo sapiens | 2 | 0.7589 |
| Prostaglandin reductase 2 | Q8N8N7 | PTGR2_HUMAN | Homo sapiens | 2 | 0.7589 |
| Mineralocorticoid receptor | P08235 | MCR_HUMAN | Homo sapiens | 2 | 0.7577 |
| Mineralocorticoid receptor | P08235 | MCR_HUMAN | Homo sapiens | 2 | 0.7577 |
| Nuclear receptor subfamily 1 group I member 3 | O35627 | NR1I3_MOUSE | Mus musculus | 2 | 0.7563 |
| Nuclear receptor subfamily 1 group I member 3 | O35627 | NR1I3_MOUSE | Mus musculus | 2 | 0.7563 |
| Sex hormone-binding globulin | P04278 | SHBG_HUMAN | Homo sapiens | 3 | 0.7557 |
| Sex hormone-binding globulin | P04278 | SHBG_HUMAN | Homo sapiens | 3 | 0.7557 |
| Androgen receptor | P10275 | ANDR_HUMAN | Homo sapiens | 3 | 0.7551 |
| Androgen receptor | P10275 | ANDR_HUMAN | Homo sapiens | 3 | 0.7551 |
| Aldo-keto reductase family 1 member D1 | P51857 | AK1D1_HUMAN | Homo sapiens | 2 | 0.7542 |
| Aldo-keto reductase family 1 member D1 | P51857 | AK1D1_HUMAN | Homo sapiens | 2 | 0.7542 |
| Steroid Delta-isomerase | P07445 | SDIS_PSEPU | Pseudomonas putida | 2 | 0.7528 |
| Steroid Delta-isomerase | P07445 | SDIS_PSEPU | Pseudomonas putida | 2 | 0.7528 |
| Mineralocorticoid receptor | P08235 | MCR_HUMAN | Homo sapiens | 3 | 0.7527 |
| Mineralocorticoid receptor | P08235 | MCR_HUMAN | Homo sapiens | 3 | 0.7527 |
| Gibberellin receptor GID1 | Q6L545 | GID1_ORYSJ | Oryza sativa subsp. japonica | 3 | 0.7508 |
| Gibberellin receptor GID1 | Q6L545 | GID1_ORYSJ | Oryza sativa subsp. japonica | 3 | 0.7508 |
| Cytochrome P450 monooxygenase | Q5YNS8 | Q5YNS8_NOCFA | Nocardia farcinica | 2 | 0.7501 |
| Cytochrome P450 monooxygenase | Q5YNS8 | Q5YNS8_NOCFA | Nocardia farcinica | 2 | 0.7501 |
| Cytochrome P450 monooxygenase | Q5YNS8 | Q5YNS8_NOCFA | Nocardia farcinica | 2 | 0.7465 |
| Cytochrome P450 monooxygenase | Q5YNS8 | Q5YNS8_NOCFA | Nocardia farcinica | 2 | 0.7465 |
| Androgen receptor | P10275 | ANDR_HUMAN | Homo sapiens | 3 | 0.7456 |
| Androgen receptor | P10275 | ANDR_HUMAN | Homo sapiens | 3 | 0.7456 |
| Gibberellin receptor GID1A | Q9MAA7 | GID1A_ARATH | Arabidopsis thaliana | 3 | 0.7450 |
| Gibberellin receptor GID1A | Q9MAA7 | GID1A_ARATH | Arabidopsis thaliana | 3 | 0.7450 |
| Androgen receptor | P10275 | ANDR_HUMAN | Homo sapiens | 3 | 0.7442 |
| Androgen receptor | P10275 | ANDR_HUMAN | Homo sapiens | 3 | 0.7442 |
| Aldo-keto reductase family 1 member D1 | P51857 | AK1D1_HUMAN | Homo sapiens | 3 | 0.7440 |
| Aldo-keto reductase family 1 member D1 | P51857 | AK1D1_HUMAN | Homo sapiens | 3 | 0.7440 |
| NPC intracellular cholesterol transporter 1 | O15118 | NPC1_HUMAN | Homo sapiens | 2 | 0.7434 |
| NPC intracellular cholesterol transporter 1 | O15118 | NPC1_HUMAN | Homo sapiens | 2 | 0.7434 |
| Multidrug transporter MdfA | P0AEY8 | MDFA_ECOLI | Escherichia coli | 3 | 0.7416 |
| Multidrug transporter MdfA | P0AEY8 | MDFA_ECOLI | Escherichia coli | 3 | 0.7416 |
| Androgen receptor | P10275 | ANDR_HUMAN | Homo sapiens | 3 | 0.7415 |
| Androgen receptor | P10275 | ANDR_HUMAN | Homo sapiens | 3 | 0.7415 |
| Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial | Q0QF01 | SDHA_PIG | Sus scrofa | 2 | 0.7407 |
| Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial | Q0QF01 | SDHA_PIG | Sus scrofa | 2 | 0.7407 |
| 17-beta-hydroxysteroid dehydrogenase type 1 | P14061 | DHB1_HUMAN | Homo sapiens | 2 | 0.7331 |
| 17-beta-hydroxysteroid dehydrogenase type 1 | P14061 | DHB1_HUMAN | Homo sapiens | 2 | 0.7331 |
| Androgen receptor | P10275 | ANDR_HUMAN | Homo sapiens | 3 | 0.7316 |
| Androgen receptor | P10275 | ANDR_HUMAN | Homo sapiens | 3 | 0.7316 |
| Progesterone receptor | P06401 | PRGR_HUMAN | Homo sapiens | 2 | 0.7295 |
| Progesterone receptor | P06401 | PRGR_HUMAN | Homo sapiens | 2 | 0.7295 |
| Androgen receptor | P10275 | ANDR_HUMAN | Homo sapiens | 3 | 0.7290 |
| Androgen receptor | P10275 | ANDR_HUMAN | Homo sapiens | 3 | 0.7290 |
| Abscisic acid receptor PYL3 | Q9SSM7 | PYL3_ARATH | Arabidopsis thaliana | 2 | 0.7228 |
| Abscisic acid receptor PYL3 | Q9SSM7 | PYL3_ARATH | Arabidopsis thaliana | 2 | 0.7228 |
| Nuclear receptor ROR-beta | P45446 | RORB_RAT | Rattus norvegicus | 2 | 0.7222 |
| Nuclear receptor ROR-beta | P45446 | RORB_RAT | Rattus norvegicus | 2 | 0.7222 |
| Rhodopsin | P02699 | OPSD_BOVIN | Bos taurus | 2 | 0.7214 |
| Rhodopsin | P02699 | OPSD_BOVIN | Bos taurus | 2 | 0.7214 |
| Aldo-keto reductase family 1 member C1 | Q04828 | AK1C1_HUMAN | Homo sapiens | 2 | 0.7154 |
| Aldo-keto reductase family 1 member C1 | Q04828 | AK1C1_HUMAN | Homo sapiens | 2 | 0.7154 |
| Jasmonoyl--L-amino acid synthetase JAR1 | Q9SKE2 | JAR1_ARATH | Arabidopsis thaliana | 3 | 0.7148 |
| Jasmonoyl--L-amino acid synthetase JAR1 | Q9SKE2 | JAR1_ARATH | Arabidopsis thaliana | 3 | 0.7148 |
| Pentaerythritol tetranitrate reductase | P71278 | P71278_ENTCL | Enterobacter cloacae | 2 | 0.7100 |
| Pentaerythritol tetranitrate reductase | P71278 | P71278_ENTCL | Enterobacter cloacae | 2 | 0.7100 |
| 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase | P19992 | HSD_STREX | Streptomyces exfoliatus | 2 | 0.7067 |
| 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase | P19992 | HSD_STREX | Streptomyces exfoliatus | 2 | 0.7067 |
| Neocarzinostatin | P0A3R9 | NCZS_STRCZ | Streptomyces carzinostaticus | 2 | 0.7054 |
| Neocarzinostatin | P0A3R9 | NCZS_STRCZ | Streptomyces carzinostaticus | 2 | 0.7054 |
| Mineralocorticoid receptor | P08235 | MCR_HUMAN | Homo sapiens | 2 | 0.7052 |
| Mineralocorticoid receptor | P08235 | MCR_HUMAN | Homo sapiens | 2 | 0.7052 |
| Pentaerythritol tetranitrate reductase | P71278 | P71278_ENTCL | Enterobacter cloacae | 2 | 0.7045 |
| Pentaerythritol tetranitrate reductase | P71278 | P71278_ENTCL | Enterobacter cloacae | 2 | 0.7045 |
| Sex hormone-binding globulin | P04278 | SHBG_HUMAN | Homo sapiens | 2 | 0.7014 |
| Sex hormone-binding globulin | P04278 | SHBG_HUMAN | Homo sapiens | 2 | 0.7014 |