Callyspongamide A - Compound Card

Callyspongamide A

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Callyspongamide A

Structure
Zoomed Structure
  • Family: Animalia - Callyspongiidae
  • Kingdom: Animalia
  • Class: Alkaloid
    • Subclass: Amide
Canonical Smiles C#C/C=C\CCCCCCCCC#CCCC(=O)NCCc1ccccc1
InChI InChI=1S/C25H33NO/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-18-21-25(27)26-23-22-24-19-16-15-17-20-24/h1,3-4,15-17,19-20H,5-12,18,21-23H2,(H,26,27)/b4-3-
InChIKey SHXHAJNGQUTIEX-ARJAWSKDSA-N
Formula C25H33NO
HBA 1
HBD 1
MW 363.55
Rotatable Bonds 13
TPSA 29.1
LogP 5.44
Number Rings 1
Number Aromatic Rings 1
Heavy Atom Count 27
Formal Charge 0
Fraction CSP3 0.48
Exact Mass 363.26
Number of Lipinski Rule Violations 1
# Species Family Kingdom NCBI Taxonomy ID
1 Callyspongia fistularis Callyspongiidae Animalia 178537

Showing of synonyms

  • Youssef DTA, van Soest RWM, et al. (2003). Callyspongamide A, a new cytotoxic polyacetylenic amide from the Red Sea sponge Callyspongia fistularis. Journal of Natural Products,2003,66(6),861-862. [View] [PubMed]
Pubchem: 10981352
Nmrshiftdb2: 70076690

No compound-protein relationship available.

Structure

SMILES: c1ccccc1

Level: 0

Mol. Weight: 363.55 g/mol

Cytotoxic

Absorption

Caco-2 (logPapp)
-4.86
Human Oral Bioavailability 20%
Bioavailable
Human Intestinal Absorption
Absorbed
Madin-Darby Canine Kidney
-4.16
Human Oral Bioavailability 50%
Non-Bioavailable
P-Glycoprotein Inhibitor
Non-Inhibitor
P-Glycoprotein Substrate
Non-Substrate
Skin Permeability
-2.75

Distribution

Blood-Brain Barrier (CNS)
-
Blood-Brain Barrier
Penetrable
Fraction Unbound (Human)
1.64
Plasma Protein Binding
74.05
Steady State Volume of Distribution
-

Metabolism

Breast Cancer Resistance Protein
Inhibitor
CYP 1A2 Inhibitor
Inhibitor
CYP 1A2 Substrate
Non-Substrate
CYP 2C19 Inhibitor
Inhibitor
CYP 2C19 Substrate
Non-Substrate
CYP 2C9 Inhibitor
Inhibitor
CYP 2C9 Substrate
Non-Substrate
CYP 2D6 Inhibitor
Non-Inhibitor
CYP 2D6 Substrate
Substrate
CYP 3A4 Inhibitor
Inhibitor
CYP 3A4 Substrate
Non-Substrate
OATP1B1
Non-Inhibitor
OATP1B3
Non-Inhibitor

Excretion

Clearance
3.17
Organic Cation Transporter 2
Non-Inhibitor
Half-Life of Drug
-

Toxicity

AMES Mutagenesis
Safe
Avian
Safe
Bee
Toxic
Bioconcentration Factor
1.42
Biodegradation
Safe
Carcinogenesis
Toxic
Crustacean
Toxic
Liver Injury I (DILI)
Safe
Eye Corrosion
Safe
Eye Irritation
Safe
Maximum Tolerated Dose
-1.39
Liver Injury II
Toxic
hERG Blockers
Toxic
Daphnia Maga
5.89
Micronucleos
Safe
NR-AhR
Safe
NR-AR
Safe
NR-AR-LBD
Safe
NR-Aromatase
Safe
NR-ER
Safe
NR-ER-LBD
Safe
NR-GR
Safe
NR-PPAR-gamma
Safe
NR-TR
Toxic
T. Pyriformis
-0.69
Rat (Acute)
2.21
Rat (Chronic Oral)
2.35
Fathead Minnow
4.57
Respiratory Disease
Toxic
Skin Sensitisation
Toxic
SR-ARE
Toxic
SR-ATAD5
Safe
SR-HSE
Safe
SR-MMP
Toxic
SR-p53
Safe

General Properties

Boiling Point
437.88
Hydration Free Energy
-4.83
Log(D) at pH=7.4
4.68
Log(P)
6.28
Log S
-5.98
Log(Vapor Pressure)
-8.86
Melting Point
44.43
pKa Acid
11.24
pKa Basic
3.89
Protein Name UniProt ID Entry Name Species #Pharmacophore Points Probability (0.7 ≤ Tversky Score ≤ 1.0)
3'-5' exoribonuclease Rv2179c P9WJ73 EXRBN_MYCTU Mycobacterium tuberculosis 3 0.9933
3'-5' exoribonuclease Rv2179c P9WJ73 EXRBN_MYCTU Mycobacterium tuberculosis 3 0.9933
Cyclin-dependent kinase 8 P49336 CDK8_HUMAN Homo sapiens 3 0.9886
Cyclin-dependent kinase 8 P49336 CDK8_HUMAN Homo sapiens 3 0.9886
Amine oxidase [flavin-containing] B P27338 AOFB_HUMAN Homo sapiens 3 0.9879
Amine oxidase [flavin-containing] B P27338 AOFB_HUMAN Homo sapiens 3 0.9879
Thermolysin P00800 THER_BACTH Bacillus thermoproteolyticus 3 0.9847
Thermolysin P00800 THER_BACTH Bacillus thermoproteolyticus 3 0.9847
Queuine tRNA-ribosyltransferase P28720 TGT_ZYMMO Zymomonas mobilis subsp. mobilis 3 0.9839
Queuine tRNA-ribosyltransferase P28720 TGT_ZYMMO Zymomonas mobilis subsp. mobilis 3 0.9839
Poly [ADP-ribose] polymerase 1 P09874 PARP1_HUMAN Homo sapiens 3 0.9754
Poly [ADP-ribose] polymerase 1 P09874 PARP1_HUMAN Homo sapiens 3 0.9754
Glycogen synthase kinase-3 beta P49841 GSK3B_HUMAN Homo sapiens 3 0.9680
Glycogen synthase kinase-3 beta P49841 GSK3B_HUMAN Homo sapiens 3 0.9680
Protein mono-ADP-ribosyltransferase PARP3 Q9Y6F1 PARP3_HUMAN Homo sapiens 3 0.9646
Protein mono-ADP-ribosyltransferase PARP3 Q9Y6F1 PARP3_HUMAN Homo sapiens 3 0.9646
LIM domain kinase 1 P53667 LIMK1_HUMAN Homo sapiens 3 0.9644
LIM domain kinase 1 P53667 LIMK1_HUMAN Homo sapiens 3 0.9644
Nitric oxide synthase, inducible P29477 NOS2_MOUSE Mus musculus 3 0.9641
Nitric oxide synthase, inducible P29477 NOS2_MOUSE Mus musculus 3 0.9641
Glutamate receptor 2 P19491 GRIA2_RAT Rattus norvegicus 3 0.9628
Glutamate receptor 2 P19491 GRIA2_RAT Rattus norvegicus 3 0.9628
Poly [ADP-ribose] polymerase 1 P09874 PARP1_HUMAN Homo sapiens 3 0.9619
Poly [ADP-ribose] polymerase 1 P09874 PARP1_HUMAN Homo sapiens 3 0.9619
Glutamate receptor 2 P19491 GRIA2_RAT Rattus norvegicus 3 0.9612
Glutamate receptor 2 P19491 GRIA2_RAT Rattus norvegicus 3 0.9612
ADP compounds hydrolase NudE P45799 NUDE_ECOLI Escherichia coli 3 0.9609
ADP compounds hydrolase NudE P45799 NUDE_ECOLI Escherichia coli 3 0.9609
Nitric oxide synthase, inducible P29477 NOS2_MOUSE Mus musculus 3 0.9601
Nitric oxide synthase, inducible P29477 NOS2_MOUSE Mus musculus 3 0.9601
Glutamate receptor 2 P19491 GRIA2_RAT Rattus norvegicus 3 0.9582
Glutamate receptor 2 P19491 GRIA2_RAT Rattus norvegicus 3 0.9582
RIO-type serine/threonine-protein kinase Rio1 O28471 RIO1_ARCFU Archaeoglobus fulgidus 3 0.9570
RIO-type serine/threonine-protein kinase Rio1 O28471 RIO1_ARCFU Archaeoglobus fulgidus 3 0.9570
Gag-Pol polyprotein P03369 POL_HV1A2 Human immunodeficiency virus type 1 group M subtype B 3 0.9567
Gag-Pol polyprotein P03369 POL_HV1A2 Human immunodeficiency virus type 1 group M subtype B 3 0.9567
Poly [ADP-ribose] polymerase tankyrase-2 Q9H2K2 TNKS2_HUMAN Homo sapiens 3 0.9559
Poly [ADP-ribose] polymerase tankyrase-2 Q9H2K2 TNKS2_HUMAN Homo sapiens 3 0.9559
Casein kinase II subunit alpha P68400 CSK21_HUMAN Homo sapiens 3 0.9546
Casein kinase II subunit alpha P68400 CSK21_HUMAN Homo sapiens 3 0.9546
Hexokinase-4 P35557 HXK4_HUMAN Homo sapiens 3 0.9524
Hexokinase-4 P35557 HXK4_HUMAN Homo sapiens 3 0.9524
5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase P0AF12 MTNN_ECOLI Escherichia coli 3 0.9499
5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase P0AF12 MTNN_ECOLI Escherichia coli 3 0.9499
Serine/threonine-protein kinase toxin HipA P23874 HIPA_ECOLI Escherichia coli 3 0.9481
Serine/threonine-protein kinase toxin HipA P23874 HIPA_ECOLI Escherichia coli 3 0.9481
Protein mono-ADP-ribosyltransferase PARP14 Q460N5 PAR14_HUMAN Homo sapiens 3 0.9480
Protein mono-ADP-ribosyltransferase PARP14 Q460N5 PAR14_HUMAN Homo sapiens 3 0.9480
Capsid protein Q9WBP8 Q9WBP8_9VIRU Adeno-associated virus - 1 3 0.9479
Capsid protein Q9WBP8 Q9WBP8_9VIRU Adeno-associated virus - 1 3 0.9479
Biotin carboxylase P43873 ACCC_HAEIN Haemophilus influenzae 3 0.9474
Biotin carboxylase P43873 ACCC_HAEIN Haemophilus influenzae 3 0.9474
Biotin carboxylase P24182 ACCC_ECOLI Escherichia coli 3 0.9469
Biotin carboxylase P24182 ACCC_ECOLI Escherichia coli 3 0.9469
Serine/threonine-protein kinase SKY1 Q03656 SKY1_YEAST Saccharomyces cerevisiae 3 0.9467
Serine/threonine-protein kinase SKY1 Q03656 SKY1_YEAST Saccharomyces cerevisiae 3 0.9467
Poly [ADP-ribose] polymerase tankyrase-2 Q9H2K2 TNKS2_HUMAN Homo sapiens 3 0.9465
Poly [ADP-ribose] polymerase tankyrase-2 Q9H2K2 TNKS2_HUMAN Homo sapiens 3 0.9465
cAMP-dependent protein kinase catalytic subunit alpha P05132 KAPCA_MOUSE Mus musculus 3 0.9458
cAMP-dependent protein kinase catalytic subunit alpha P05132 KAPCA_MOUSE Mus musculus 3 0.9458
Poly [ADP-ribose] polymerase 1 P09874 PARP1_HUMAN Homo sapiens 3 0.9447
Poly [ADP-ribose] polymerase 1 P09874 PARP1_HUMAN Homo sapiens 3 0.9447
Ephrin type-B receptor 2 P54763 EPHB2_MOUSE Mus musculus 3 0.9444
Ephrin type-B receptor 2 P54763 EPHB2_MOUSE Mus musculus 3 0.9444
Protein mono-ADP-ribosyltransferase PARP10 Q53GL7 PAR10_HUMAN Homo sapiens 3 0.9443
Protein mono-ADP-ribosyltransferase PARP10 Q53GL7 PAR10_HUMAN Homo sapiens 3 0.9443
ATP-dependent molecular chaperone HSP82 P02829 HSP82_YEAST Saccharomyces cerevisiae 3 0.9425
ATP-dependent molecular chaperone HSP82 P02829 HSP82_YEAST Saccharomyces cerevisiae 3 0.9425
Serine/threonine-protein kinase Chk1 O14757 CHK1_HUMAN Homo sapiens 3 0.9417
Serine/threonine-protein kinase Chk1 O14757 CHK1_HUMAN Homo sapiens 3 0.9417
Protein kinase C iota type Q62074 KPCI_MOUSE Mus musculus 3 0.9411
Protein kinase C iota type Q62074 KPCI_MOUSE Mus musculus 3 0.9411
Thermolysin P00800 THER_BACTH Bacillus thermoproteolyticus 3 0.9391
Thermolysin P00800 THER_BACTH Bacillus thermoproteolyticus 3 0.9391
Fibroblast growth factor receptor 2 P21802 FGFR2_HUMAN Homo sapiens 3 0.9383
Fibroblast growth factor receptor 2 P21802 FGFR2_HUMAN Homo sapiens 3 0.9383
Myosin heavy chain kinase A P42527 MHCKA_DICDI Dictyostelium discoideum 3 0.9382
Myosin heavy chain kinase A P42527 MHCKA_DICDI Dictyostelium discoideum 3 0.9382
Lactoperoxidase P80025 PERL_BOVIN Bos taurus 3 0.9377
Lactoperoxidase P80025 PERL_BOVIN Bos taurus 3 0.9377
Fibroblast growth factor receptor 2 P21802 FGFR2_HUMAN Homo sapiens 3 0.9366
Fibroblast growth factor receptor 2 P21802 FGFR2_HUMAN Homo sapiens 3 0.9366
NAD-dependent protein deacetylase Q9WYW0 NPD_THEMA Thermotoga maritima 3 0.9360
NAD-dependent protein deacetylase Q9WYW0 NPD_THEMA Thermotoga maritima 3 0.9360
Mitogen-activated protein kinase kinase kinase 5 Q99683 M3K5_HUMAN Homo sapiens 3 0.9356
Mitogen-activated protein kinase kinase kinase 5 Q99683 M3K5_HUMAN Homo sapiens 3 0.9356
Prothrombin P00734 THRB_HUMAN Homo sapiens 3 0.9341
Prothrombin P00734 THRB_HUMAN Homo sapiens 3 0.9341
Poly [ADP-ribose] polymerase tankyrase-2 Q9H2K2 TNKS2_HUMAN Homo sapiens 3 0.9337
Poly [ADP-ribose] polymerase tankyrase-2 Q9H2K2 TNKS2_HUMAN Homo sapiens 3 0.9337
Nicotinamide phosphoribosyltransferase P43490 NAMPT_HUMAN Homo sapiens 3 0.9304
Nicotinamide phosphoribosyltransferase P43490 NAMPT_HUMAN Homo sapiens 3 0.9304
Nitric oxide synthase 3 P29474 NOS3_HUMAN Homo sapiens 3 0.9297
Nitric oxide synthase 3 P29474 NOS3_HUMAN Homo sapiens 3 0.9297
Poly [ADP-ribose] polymerase 1 P09874 PARP1_HUMAN Homo sapiens 3 0.9267
Poly [ADP-ribose] polymerase 1 P09874 PARP1_HUMAN Homo sapiens 3 0.9267
L-lactate dehydrogenase A chain P04642 LDHA_RAT Rattus norvegicus 3 0.9267
L-lactate dehydrogenase A chain P04642 LDHA_RAT Rattus norvegicus 3 0.9267
Prothrombin P00734 THRB_HUMAN Homo sapiens 3 0.9240
Prothrombin P00734 THRB_HUMAN Homo sapiens 3 0.9240
Basic phospholipase A2 VRV-PL-VIIIa P59071 PA2B8_DABRR Daboia russelii 3 0.9219
Basic phospholipase A2 VRV-PL-VIIIa P59071 PA2B8_DABRR Daboia russelii 3 0.9219
Phosphotriesterase Q5KZU5 Q5KZU5_GEOKA Geobacillus kaustophilus 3 0.9183
Phosphotriesterase Q5KZU5 Q5KZU5_GEOKA Geobacillus kaustophilus 3 0.9183
Diphtheria toxin P00588 DTX_CORBE Corynephage beta 3 0.9177
Diphtheria toxin P00588 DTX_CORBE Corynephage beta 3 0.9177
Matrix metalloproteinase-20 O60882 MMP20_HUMAN Homo sapiens 3 0.9126
Matrix metalloproteinase-20 O60882 MMP20_HUMAN Homo sapiens 3 0.9126
Glycogen synthase kinase-3 beta P49841 GSK3B_HUMAN Homo sapiens 3 0.9076
Glycogen synthase kinase-3 beta P49841 GSK3B_HUMAN Homo sapiens 3 0.9076
Mitogen-activated protein kinase 1 P28482 MK01_HUMAN Homo sapiens 3 0.8952
Mitogen-activated protein kinase 1 P28482 MK01_HUMAN Homo sapiens 3 0.8952
Cyclin-dependent kinase 2 P24941 CDK2_HUMAN Homo sapiens 3 0.8904
Cyclin-dependent kinase 2 P24941 CDK2_HUMAN Homo sapiens 3 0.8904
ADP-ribosylation factor 1 P84077 ARF1_HUMAN Homo sapiens 2 0.8807
ADP-ribosylation factor 1 P84077 ARF1_HUMAN Homo sapiens 2 0.8807
Class B acid phosphatase Q540U1 APHA_SALTM Salmonella typhimurium 2 0.8627
Class B acid phosphatase Q540U1 APHA_SALTM Salmonella typhimurium 2 0.8627
Adenosine kinase Q9TVW2 ADK_TOXGO Toxoplasma gondii 3 0.8231
Adenosine kinase Q9TVW2 ADK_TOXGO Toxoplasma gondii 3 0.8231
rRNA methylase Q8DSS3 Q8DSS3_STRMU Streptococcus mutans serotype c 2 0.8230
rRNA methylase Q8DSS3 Q8DSS3_STRMU Streptococcus mutans serotype c 2 0.8230
Purine nucleoside phosphorylase DeoD-type P0ABP8 DEOD_ECOLI Escherichia coli 3 0.8221
Purine nucleoside phosphorylase DeoD-type P0ABP8 DEOD_ECOLI Escherichia coli 3 0.8221
Adenosine kinase Q9TVW2 ADK_TOXGO Toxoplasma gondii 3 0.8208
Adenosine kinase Q9TVW2 ADK_TOXGO Toxoplasma gondii 3 0.8208
Basic phospholipase A2 VRV-PL-VIIIa P59071 PA2B8_DABRR Daboia russelii 2 0.8180
Basic phospholipase A2 VRV-PL-VIIIa P59071 PA2B8_DABRR Daboia russelii 2 0.8180
MAP kinase-activated protein kinase 2 P49137 MAPK2_HUMAN Homo sapiens 3 0.8130
MAP kinase-activated protein kinase 2 P49137 MAPK2_HUMAN Homo sapiens 3 0.8130
Cyclic nucleotide-binding domain-containing protein E0RR11 E0RR11_SPITD Spirochaeta thermophila 2 0.8106
Cyclic nucleotide-binding domain-containing protein E0RR11 E0RR11_SPITD Spirochaeta thermophila 2 0.8106
NAD(P)H-hydrate epimerase Q8K4Z3 NNRE_MOUSE Mus musculus 3 0.8103
NAD(P)H-hydrate epimerase Q8K4Z3 NNRE_MOUSE Mus musculus 3 0.8103
Indole-3-glycerol phosphate synthase P9WFX7 TRPC_MYCTU Mycobacterium tuberculosis 2 0.8094
Indole-3-glycerol phosphate synthase P9WFX7 TRPC_MYCTU Mycobacterium tuberculosis 2 0.8094
N-acetyltransferase domain-containing protein Q9HV14 Q9HV14_PSEAE Pseudomonas aeruginosa 2 0.8085
N-acetyltransferase domain-containing protein Q9HV14 Q9HV14_PSEAE Pseudomonas aeruginosa 2 0.8085
Cyclin-dependent kinase 2 P24941 CDK2_HUMAN Homo sapiens 3 0.8075
Cyclin-dependent kinase 2 P24941 CDK2_HUMAN Homo sapiens 3 0.8075
Prenyltransferase Q4R2T2 Q4R2T2_STRC1 Streptomyces sp 2 0.8059
Prenyltransferase Q4R2T2 Q4R2T2_STRC1 Streptomyces sp 2 0.8059
Mycocyclosin synthase P9WPP7 CP121_MYCTU Mycobacterium tuberculosis 2 0.7980
Mycocyclosin synthase P9WPP7 CP121_MYCTU Mycobacterium tuberculosis 2 0.7980
Streptavidin P22629 SAV_STRAV Streptomyces avidinii 3 0.7951
Streptavidin P22629 SAV_STRAV Streptomyces avidinii 3 0.7951
Fibroblast growth factor receptor 2 P21802 FGFR2_HUMAN Homo sapiens 3 0.7920
Fibroblast growth factor receptor 2 P21802 FGFR2_HUMAN Homo sapiens 3 0.7920
Adenosine 5'-monophosphoramidase HINT1 P80912 HINT1_RABIT Oryctolagus cuniculus 2 0.7888
Adenosine 5'-monophosphoramidase HINT1 P80912 HINT1_RABIT Oryctolagus cuniculus 2 0.7888
histone deacetylase A5H660 A5H660_SCHMA Schistosoma mansoni 3 0.7880
histone deacetylase A5H660 A5H660_SCHMA Schistosoma mansoni 3 0.7880
4-hydroxy-7-methoxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl glucoside beta-D-glucosidase 1, chloroplastic P49235 HGGL1_MAIZE Zea mays 2 0.7863
4-hydroxy-7-methoxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl glucoside beta-D-glucosidase 1, chloroplastic P49235 HGGL1_MAIZE Zea mays 2 0.7863
Glutamate receptor 2 P19491 GRIA2_RAT Rattus norvegicus 2 0.7858
Glutamate receptor 2 P19491 GRIA2_RAT Rattus norvegicus 2 0.7858
Cyclin-dependent kinase 2 P24941 CDK2_HUMAN Homo sapiens 3 0.7857
Cyclin-dependent kinase 2 P24941 CDK2_HUMAN Homo sapiens 3 0.7857
Adenosine 5'-monophosphoramidase HINT1 P49773 HINT1_HUMAN Homo sapiens 3 0.7855
Adenosine 5'-monophosphoramidase HINT1 P49773 HINT1_HUMAN Homo sapiens 3 0.7855
Cyclic nucleotide-gated potassium channel mll3241 Q98GN8 CNGK1_RHILO Mesorhizobium japonicum) 2 0.7839
Cyclic nucleotide-gated potassium channel mll3241 Q98GN8 CNGK1_RHILO Mesorhizobium japonicum) 2 0.7839
Transitional endoplasmic reticulum ATPase P55072 TERA_HUMAN Homo sapiens 3 0.7835
Transitional endoplasmic reticulum ATPase P55072 TERA_HUMAN Homo sapiens 3 0.7835
cGMP-dependent protein kinase 2 Q13237 KGP2_HUMAN Homo sapiens 2 0.7822
cGMP-dependent protein kinase 2 Q13237 KGP2_HUMAN Homo sapiens 2 0.7822
Malate synthase G P9WK17 MASZ_MYCTU Mycobacterium tuberculosis 3 0.7821
Malate synthase G P9WK17 MASZ_MYCTU Mycobacterium tuberculosis 3 0.7821
Chloramphenicol 3-O phosphotransferase Q56148 CPT_STRVP Streptomyces venezuelae 3 0.7820
Chloramphenicol 3-O phosphotransferase Q56148 CPT_STRVP Streptomyces venezuelae 3 0.7820
Class 10 plant pathogenesis-related protein 2B Q9LLQ2 P102B_LUPLU Lupinus luteus 2 0.7818
Class 10 plant pathogenesis-related protein 2B Q9LLQ2 P102B_LUPLU Lupinus luteus 2 0.7818
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 Q9Y3Q4 HCN4_HUMAN Homo sapiens 2 0.7817
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 Q9Y3Q4 HCN4_HUMAN Homo sapiens 2 0.7817
Prothrombin P00734 THRB_HUMAN Homo sapiens 3 0.7814
Vascular endothelial growth factor receptor 2 P35968 VGFR2_HUMAN Homo sapiens 3 0.7814
Vascular endothelial growth factor receptor 2 P35968 VGFR2_HUMAN Homo sapiens 3 0.7814
Prothrombin P00734 THRB_HUMAN Homo sapiens 3 0.7814
DNA mismatch repair protein MutS P23909 MUTS_ECOLI Escherichia coli 3 0.7810
DNA mismatch repair protein MutS P23909 MUTS_ECOLI Escherichia coli 3 0.7810
Cyclin-dependent kinase 2 P24941 CDK2_HUMAN Homo sapiens 3 0.7805
Cyclin-dependent kinase 2 P24941 CDK2_HUMAN Homo sapiens 3 0.7805
Glycogen phosphorylase, muscle form P00489 PYGM_RABIT Oryctolagus cuniculus 3 0.7803
Focal adhesion kinase 1 Q05397 FAK1_HUMAN Homo sapiens 3 0.7803
Focal adhesion kinase 1 Q05397 FAK1_HUMAN Homo sapiens 3 0.7803
Glycogen phosphorylase, muscle form P00489 PYGM_RABIT Oryctolagus cuniculus 3 0.7803
Peroxidase C1A P00433 PER1A_ARMRU Armoracia rusticana 2 0.7798
Peroxidase C1A P00433 PER1A_ARMRU Armoracia rusticana 2 0.7798
Adenine DNA glycosylase P83847 MUTY_GEOSE Geobacillus stearothermophilus 3 0.7797
Adenine DNA glycosylase P83847 MUTY_GEOSE Geobacillus stearothermophilus 3 0.7797
Prothrombin P00734 THRB_HUMAN Homo sapiens 3 0.7792
Prothrombin P00734 THRB_HUMAN Homo sapiens 3 0.7792
Purine phosphoribosyltransferase (GpT-1) Q97W95 Q97W95_SACS2 Saccharolobus solfataricus 3 0.7791
Purine phosphoribosyltransferase (GpT-1) Q97W95 Q97W95_SACS2 Saccharolobus solfataricus 3 0.7791
Adenosine 5'-monophosphoramidase HINT1 P49773 HINT1_HUMAN Homo sapiens 3 0.7773
Adenosine 5'-monophosphoramidase HINT1 P49773 HINT1_HUMAN Homo sapiens 3 0.7773
cGMP-dependent protein kinase 1 Q13976 KGP1_HUMAN Homo sapiens 2 0.7765
cGMP-dependent protein kinase 1 Q13976 KGP1_HUMAN Homo sapiens 2 0.7765
S-adenosylmethionine decarboxylase proenzyme P17707 DCAM_HUMAN Homo sapiens 3 0.7762
S-adenosylmethionine decarboxylase proenzyme P17707 DCAM_HUMAN Homo sapiens 3 0.7762
Queuine tRNA-ribosyltransferase P28720 TGT_ZYMMO Zymomonas mobilis subsp. mobilis 3 0.7759
Queuine tRNA-ribosyltransferase P28720 TGT_ZYMMO Zymomonas mobilis subsp. mobilis 3 0.7759
Serine/threonine-protein kinase Chk1 O14757 CHK1_HUMAN Homo sapiens 3 0.7751
Serine/threonine-protein kinase Chk1 O14757 CHK1_HUMAN Homo sapiens 3 0.7751
Thermolysin P00800 THER_BACTH Bacillus thermoproteolyticus 3 0.7750
Alpha/beta hydrolase fold protein D2J2T6 D2J2T6_9RHIZ Ochrobactrum sp. T63 3 0.7750
Thermolysin P00800 THER_BACTH Bacillus thermoproteolyticus 3 0.7750
Alpha/beta hydrolase fold protein D2J2T6 D2J2T6_9RHIZ Ochrobactrum sp. T63 3 0.7750
Receptor-interacting serine/threonine-protein kinase 1 Q13546 RIPK1_HUMAN Homo sapiens 3 0.7746
Pentaerythritol tetranitrate reductase P71278 P71278_ENTCL Enterobacter cloacae 2 0.7746
Pentaerythritol tetranitrate reductase P71278 P71278_ENTCL Enterobacter cloacae 2 0.7746
Receptor-interacting serine/threonine-protein kinase 1 Q13546 RIPK1_HUMAN Homo sapiens 3 0.7746
Tetracycline repressor protein class D P0ACT4 TETR4_ECOLX Escherichia coli 2 0.7744
Tetracycline repressor protein class D P0ACT4 TETR4_ECOLX Escherichia coli 2 0.7744
Valacyclovir hydrolase Q86WA6 BPHL_HUMAN Homo sapiens 2 0.7743
Endoplasmin P41148 ENPL_CANLF Canis lupus familiaris 3 0.7743
Valacyclovir hydrolase Q86WA6 BPHL_HUMAN Homo sapiens 2 0.7743
Endoplasmin P41148 ENPL_CANLF Canis lupus familiaris 3 0.7743
Beta-lactamase Q9L5C8 Q9L5C8_ECOLX Escherichia coli 3 0.7733
Beta-lactamase Q9L5C8 Q9L5C8_ECOLX Escherichia coli 3 0.7733
ATP-dependent molecular chaperone HSP82 P02829 HSP82_YEAST Saccharomyces cerevisiae 2 0.7731
ATP-dependent molecular chaperone HSP82 P02829 HSP82_YEAST Saccharomyces cerevisiae 2 0.7731
DNA mismatch repair protein Msh2 P43246 MSH2_HUMAN Homo sapiens 3 0.7730
DNA mismatch repair protein Msh2 P43246 MSH2_HUMAN Homo sapiens 3 0.7730
cAMP-dependent protein kinase type I-alpha regulatory subunit P00514 KAP0_BOVIN Bos taurus 2 0.7728
cAMP-dependent protein kinase type I-alpha regulatory subunit P00514 KAP0_BOVIN Bos taurus 2 0.7728
Queuine tRNA-ribosyltransferase P28720 TGT_ZYMMO Zymomonas mobilis subsp. mobilis 3 0.7727
Queuine tRNA-ribosyltransferase P28720 TGT_ZYMMO Zymomonas mobilis subsp. mobilis 3 0.7727
SKP1-like protein 1A Q39255 SKP1A_ARATH Arabidopsis thaliana 3 0.7727
SKP1-like protein 1A Q39255 SKP1A_ARATH Arabidopsis thaliana 3 0.7727
cAMP-dependent protein kinase type II-beta regulatory subunit P12369 KAP3_RAT Rattus norvegicus 2 0.7726
cAMP-dependent protein kinase type II-beta regulatory subunit P12369 KAP3_RAT Rattus norvegicus 2 0.7726
Chromosomal replication initiator protein DnaA P46798 DNAA_THEMA Thermotoga maritima 3 0.7726
Chromosomal replication initiator protein DnaA P46798 DNAA_THEMA Thermotoga maritima 3 0.7726
Aurora kinase A O14965 AURKA_HUMAN Homo sapiens 3 0.7723
Aurora kinase A O14965 AURKA_HUMAN Homo sapiens 3 0.7723
Tetracycline repressor protein class H P51561 TETR8_PASMD Pasteurella multocida 2 0.7722
Tetracycline repressor protein class H P51561 TETR8_PASMD Pasteurella multocida 2 0.7722
Mitogen-activated protein kinase 1 P63086 MK01_RAT Rattus norvegicus 3 0.7720
Mitogen-activated protein kinase 1 P63086 MK01_RAT Rattus norvegicus 3 0.7720
cAMP-dependent protein kinase type I-alpha regulatory subunit P00514 KAP0_BOVIN Bos taurus 2 0.7714
cAMP-dependent protein kinase type I-alpha regulatory subunit P00514 KAP0_BOVIN Bos taurus 2 0.7714
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 O88703 HCN2_MOUSE Mus musculus 2 0.7709
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 O88703 HCN2_MOUSE Mus musculus 2 0.7709
Aurora kinase A O14965 AURKA_HUMAN Homo sapiens 3 0.7708
Aurora kinase A O14965 AURKA_HUMAN Homo sapiens 3 0.7708
Putative S-adenosyl-L-methionine-dependent methyltransferase ML2640 Q9CCZ4 Y2640_MYCLE Mycobacterium leprae 3 0.7702
Putative S-adenosyl-L-methionine-dependent methyltransferase ML2640 Q9CCZ4 Y2640_MYCLE Mycobacterium leprae 3 0.7702
RNA-dependent RNA polymerase Q6A562 Q6A562_9VIRU Thosea asigna virus 2 0.7699
RNA-dependent RNA polymerase Q6A562 Q6A562_9VIRU Thosea asigna virus 2 0.7699
Heat shock protein HSP 90-alpha P07900 HS90A_HUMAN Homo sapiens 2 0.7696
Heat shock protein HSP 90-alpha P07900 HS90A_HUMAN Homo sapiens 2 0.7696
Aurora kinase A O14965 AURKA_HUMAN Homo sapiens 3 0.7693
Aurora kinase A O14965 AURKA_HUMAN Homo sapiens 3 0.7693
Aurora kinase A O14965 AURKA_HUMAN Homo sapiens 3 0.7691
Aurora kinase A O14965 AURKA_HUMAN Homo sapiens 3 0.7691
cGMP-dependent protein kinase 1 Q13976 KGP1_HUMAN Homo sapiens 2 0.7690
cGMP-dependent protein kinase 1 Q13976 KGP1_HUMAN Homo sapiens 2 0.7690
DNA adenine methylase P0AEE8 DMA_ECOLI Escherichia coli 3 0.7689
DNA adenine methylase P0AEE8 DMA_ECOLI Escherichia coli 3 0.7689
Mycinamicin VI 2''-O-methyltransferase Q83WF2 MYCE_MICGR Micromonospora griseorubida 3 0.7679
Mycinamicin VI 2''-O-methyltransferase Q83WF2 MYCE_MICGR Micromonospora griseorubida 3 0.7679
Casein kinase II subunit alpha P68400 CSK21_HUMAN Homo sapiens 3 0.7676
Casein kinase II subunit alpha P68400 CSK21_HUMAN Homo sapiens 3 0.7676
Vanillyl-alcohol oxidase P56216 VAOX_PENSI Penicillium simplicissimum 3 0.7674
Vanillyl-alcohol oxidase P56216 VAOX_PENSI Penicillium simplicissimum 3 0.7674
Serine/threonine-protein kinase Chk1 O14757 CHK1_HUMAN Homo sapiens 3 0.7672
Serine/threonine-protein kinase Chk1 O14757 CHK1_HUMAN Homo sapiens 3 0.7672
Queuine tRNA-ribosyltransferase P28720 TGT_ZYMMO Zymomonas mobilis subsp. mobilis 3 0.7669
Queuine tRNA-ribosyltransferase P28720 TGT_ZYMMO Zymomonas mobilis subsp. mobilis 3 0.7669
cAMP-dependent protein kinase type I-alpha regulatory subunit P00514 KAP0_BOVIN Bos taurus 2 0.7665
cAMP-dependent protein kinase type I-alpha regulatory subunit P00514 KAP0_BOVIN Bos taurus 2 0.7665
Flavin reductase like domain-containing protein Q4UKE8 Q4UKE8_RICFE Rickettsia felis 3 0.7664
Flavin reductase like domain-containing protein Q4UKE8 Q4UKE8_RICFE Rickettsia felis 3 0.7664
Adenosine kinase Q9TVW2 ADK_TOXGO Toxoplasma gondii 3 0.7663
Adenosine kinase Q9TVW2 ADK_TOXGO Toxoplasma gondii 3 0.7663
Prostaglandin F2a synthase Q8I6L9 Q8I6L9_TRYCR Trypanosoma cruzi 2 0.7661
Prostaglandin F2a synthase Q8I6L9 Q8I6L9_TRYCR Trypanosoma cruzi 2 0.7661
Aspartokinase 1, chloroplastic Q9LYU8 AK1_ARATH Arabidopsis thaliana 3 0.7657
Aspartokinase 1, chloroplastic Q9LYU8 AK1_ARATH Arabidopsis thaliana 3 0.7657
Queuine tRNA-ribosyltransferase P28720 TGT_ZYMMO Zymomonas mobilis subsp. mobilis 3 0.7657
Queuine tRNA-ribosyltransferase P28720 TGT_ZYMMO Zymomonas mobilis subsp. mobilis 3 0.7657
Disintegrin and metalloproteinase domain-containing protein 17 P78536 ADA17_HUMAN Homo sapiens 2 0.7653
Disintegrin and metalloproteinase domain-containing protein 17 P78536 ADA17_HUMAN Homo sapiens 2 0.7653
Mannosylglycerate synthase D0MI02 D0MI02_RHOM4 Rhodothermus marinus 3 0.7635
ADP-ribosylation factor 1 P84080 ARF1_BOVIN Bos taurus 2 0.7635
Mannosylglycerate synthase D0MI02 D0MI02_RHOM4 Rhodothermus marinus 3 0.7635
ADP-ribosylation factor 1 P84080 ARF1_BOVIN Bos taurus 2 0.7635
Type II methyltransferase M.TaqI P14385 MTTA_THEAQ Thermus aquaticus 3 0.7632
Type II methyltransferase M.TaqI P14385 MTTA_THEAQ Thermus aquaticus 3 0.7632
Pancreatic alpha-amylase P04746 AMYP_HUMAN Homo sapiens 2 0.7626
Pancreatic alpha-amylase P04746 AMYP_HUMAN Homo sapiens 2 0.7626
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 O88703 HCN2_MOUSE Mus musculus 2 0.7625
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 O88703 HCN2_MOUSE Mus musculus 2 0.7625
Stromelysin-1 P08254 MMP3_HUMAN Homo sapiens 2 0.7617
Stromelysin-1 P08254 MMP3_HUMAN Homo sapiens 2 0.7617
Purine nucleoside phosphorylase Q9BMI9 Q9BMI9_SCHMA Schistosoma mansoni 2 0.7616
Purine nucleoside phosphorylase Q9BMI9 Q9BMI9_SCHMA Schistosoma mansoni 2 0.7616
4-hydroxy-7-methoxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl glucoside beta-D-glucosidase 1b, chloroplastic Q1XH05 HGL1B_WHEAT Triticum aestivum 3 0.7615
4-hydroxy-7-methoxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl glucoside beta-D-glucosidase 1b, chloroplastic Q1XH05 HGL1B_WHEAT Triticum aestivum 3 0.7615
Type II methyltransferase M.RsrI P14751 MTR1_RHOSH Cereibacter sphaeroides 3 0.7614
Type II methyltransferase M.RsrI P14751 MTR1_RHOSH Cereibacter sphaeroides 3 0.7614
Glutamate receptor 2 P19491 GRIA2_RAT Rattus norvegicus 3 0.7607
Glutamate receptor 2 P19491 GRIA2_RAT Rattus norvegicus 3 0.7607
Type II methyltransferase M.RsrI P14751 MTR1_RHOSH Cereibacter sphaeroides 3 0.7606
Type II methyltransferase M.RsrI P14751 MTR1_RHOSH Cereibacter sphaeroides 3 0.7606
Purine nucleoside phosphorylase P55859 PNPH_BOVIN Bos taurus 2 0.7604
cGMP-dependent protein kinase 1 Q13976 KGP1_HUMAN Homo sapiens 2 0.7604
Purine nucleoside phosphorylase P55859 PNPH_BOVIN Bos taurus 2 0.7604
cGMP-dependent protein kinase 1 Q13976 KGP1_HUMAN Homo sapiens 2 0.7604
ATP-dependent Clp protease ATP-binding subunit ClpX O25926 CLPX_HELPY Helicobacter pylori 3 0.7600
ATP-dependent Clp protease ATP-binding subunit ClpX O25926 CLPX_HELPY Helicobacter pylori 3 0.7600
3-phosphoinositide-dependent protein kinase 1 O15530 PDPK1_HUMAN Homo sapiens 3 0.7599
3-phosphoinositide-dependent protein kinase 1 O15530 PDPK1_HUMAN Homo sapiens 3 0.7599
Adenylate cyclase 2 A0A2U2H3Y1 A0A384LKY8_YERPE Yersinia pestis 2 0.7598
Adenylate cyclase 2 A0A2U2H3Y1 A0A384LKY8_YERPE Yersinia pestis 2 0.7598
Queuine tRNA-ribosyltransferase P28720 TGT_ZYMMO Zymomonas mobilis subsp. mobilis 3 0.7593
cAMP-dependent protein kinase type I-alpha regulatory subunit P00514 KAP0_BOVIN Bos taurus 2 0.7593
Queuine tRNA-ribosyltransferase P28720 TGT_ZYMMO Zymomonas mobilis subsp. mobilis 3 0.7593
cAMP-dependent protein kinase type I-alpha regulatory subunit P00514 KAP0_BOVIN Bos taurus 2 0.7593
4-hydroxy-7-methoxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl glucoside beta-D-glucosidase, chloroplastic Q9FYS3 HGGL_SECCE Secale cereale 3 0.7591
4-hydroxy-7-methoxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl glucoside beta-D-glucosidase, chloroplastic Q9FYS3 HGGL_SECCE Secale cereale 3 0.7591
NADPH dehydrogenase 1 Q02899 OYE1_SACPS Saccharomyces pastorianus 2 0.7590
NADPH dehydrogenase 1 Q02899 OYE1_SACPS Saccharomyces pastorianus 2 0.7590
Endoplasmin P41148 ENPL_CANLF Canis lupus familiaris 2 0.7586
Death-associated protein kinase 1 P53355 DAPK1_HUMAN Homo sapiens 3 0.7586
Aurora kinase A O14965 AURKA_HUMAN Homo sapiens 3 0.7586
Endoplasmin P41148 ENPL_CANLF Canis lupus familiaris 2 0.7586
Death-associated protein kinase 1 P53355 DAPK1_HUMAN Homo sapiens 3 0.7586
Aurora kinase A O14965 AURKA_HUMAN Homo sapiens 3 0.7586
Serine/threonine-protein kinase Chk1 O14757 CHK1_HUMAN Homo sapiens 3 0.7584
Serine/threonine-protein kinase Chk1 O14757 CHK1_HUMAN Homo sapiens 3 0.7584
cAMP-dependent protein kinase type I-alpha regulatory subunit P00514 KAP0_BOVIN Bos taurus 2 0.7583
cAMP-dependent protein kinase type I-alpha regulatory subunit P00514 KAP0_BOVIN Bos taurus 2 0.7583
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 Q9Y3Q4 HCN4_HUMAN Homo sapiens 2 0.7583
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 Q9Y3Q4 HCN4_HUMAN Homo sapiens 2 0.7583
uroporphyrinogen-III C-methyltransferase P95417 P95417_PSEAI Pseudomonas aeruginosa 3 0.7581
uroporphyrinogen-III C-methyltransferase P95417 P95417_PSEAI Pseudomonas aeruginosa 3 0.7581
NAD(P) transhydrogenase subunit alpha part 1 Q2RSB2 PNTAA_RHORT Rhodospirillum rubrum 3 0.7580
DNA mismatch repair protein MutS P23909 MUTS_ECOLI Escherichia coli 3 0.7580
DNA mismatch repair protein MutS P23909 MUTS_ECOLI Escherichia coli 3 0.7580
NAD(P) transhydrogenase subunit alpha part 1 Q2RSB2 PNTAA_RHORT Rhodospirillum rubrum 3 0.7580
Type II methyltransferase M.TaqI P14385 MTTA_THEAQ Thermus aquaticus 3 0.7579
Type II methyltransferase M.TaqI P14385 MTTA_THEAQ Thermus aquaticus 3 0.7579
Cyclin-dependent kinase 9 P50750 CDK9_HUMAN Homo sapiens 3 0.7577
Cyclin-dependent kinase 9 P50750 CDK9_HUMAN Homo sapiens 3 0.7577
CCA-adding enzyme O28126 CCA_ARCFU Archaeoglobus fulgidus 2 0.7576
CCA-adding enzyme O28126 CCA_ARCFU Archaeoglobus fulgidus 2 0.7576
Plasmid segregation protein ParM P11904 PARM_ECOLX Escherichia coli 3 0.7575
Plasmid segregation protein ParM P11904 PARM_ECOLX Escherichia coli 3 0.7575
Plasmid partition protein A P07620 PARA_ECOLX Escherichia coli 3 0.7574
Plasmid partition protein A P07620 PARA_ECOLX Escherichia coli 3 0.7574
Stromelysin-1 P08254 MMP3_HUMAN Homo sapiens 2 0.7571
Stromelysin-1 P08254 MMP3_HUMAN Homo sapiens 2 0.7571
Alpha/beta hydrolase fold protein D2J2T6 D2J2T6_9RHIZ Ochrobactrum sp. T63 2 0.7570
Alpha/beta hydrolase fold protein D2J2T6 D2J2T6_9RHIZ Ochrobactrum sp. T63 2 0.7570
CCA-adding enzyme O28126 CCA_ARCFU Archaeoglobus fulgidus 2 0.7563
CCA-adding enzyme O28126 CCA_ARCFU Archaeoglobus fulgidus 2 0.7563
Proto-oncogene tyrosine-protein kinase receptor Ret P07949 RET_HUMAN Homo sapiens 3 0.7561
Proto-oncogene tyrosine-protein kinase receptor Ret P07949 RET_HUMAN Homo sapiens 3 0.7561
Tyrosine-protein kinase SYK P43405 KSYK_HUMAN Homo sapiens 3 0.7560
Tyrosine-protein kinase SYK P43405 KSYK_HUMAN Homo sapiens 3 0.7560
Glutamate receptor 2 P19491 GRIA2_RAT Rattus norvegicus 3 0.7555
Serine/threonine-protein kinase PLK Q4KMI8 Q4KMI8_DANRE Danio rerio 3 0.7555
Serine/threonine-protein kinase PLK Q4KMI8 Q4KMI8_DANRE Danio rerio 3 0.7555
Glutamate receptor 2 P19491 GRIA2_RAT Rattus norvegicus 3 0.7555
APH(2'')-Id O68183 O68183_ENTCA Enterococcus casseliflavus 3 0.7553
APH(2'')-Id O68183 O68183_ENTCA Enterococcus casseliflavus 3 0.7553
Queuine tRNA-ribosyltransferase P28720 TGT_ZYMMO Zymomonas mobilis subsp. mobilis 2 0.7552
Queuine tRNA-ribosyltransferase P28720 TGT_ZYMMO Zymomonas mobilis subsp. mobilis 2 0.7552
Glutamate receptor 3 P19492 GRIA3_RAT Rattus norvegicus 3 0.7551
Glutamate receptor 3 P19492 GRIA3_RAT Rattus norvegicus 3 0.7551
Proto-oncogene tyrosine-protein kinase receptor Ret P07949 RET_HUMAN Homo sapiens 3 0.7548
Proto-oncogene tyrosine-protein kinase receptor Ret P07949 RET_HUMAN Homo sapiens 3 0.7548
Ribosyldihydronicotinamide dehydrogenase [quinone] P16083 NQO2_HUMAN Homo sapiens 2 0.7547
Ribosyldihydronicotinamide dehydrogenase [quinone] P16083 NQO2_HUMAN Homo sapiens 2 0.7547
Beta-glucosidase 12 B8AVF0 BGL12_ORYSI Oryza sativa subsp. indica 2 0.7546
Beta-glucosidase 12 B8AVF0 BGL12_ORYSI Oryza sativa subsp. indica 2 0.7546
Ribosomal RNA large subunit methyltransferase H P0C1V0 RLMH_STAAU Staphylococcus aureus 3 0.7545
Ribosomal RNA large subunit methyltransferase H P0C1V0 RLMH_STAAU Staphylococcus aureus 3 0.7545
Methyltransferase D0VX01 D0VX01_WSLV Wesselsbron virus 3 0.7542
Methyltransferase D0VX01 D0VX01_WSLV Wesselsbron virus 3 0.7542
Glucosidase II subunit alpha Q9STC1 Q9STC1_GRALE Gracilariopsis lemaneiformis 3 0.7540
Genome polyprotein A0EKU1 A0EKU1_9FLAV Meaban virus 3 0.7540
Genome polyprotein A0EKU1 A0EKU1_9FLAV Meaban virus 3 0.7540
Glucosidase II subunit alpha Q9STC1 Q9STC1_GRALE Gracilariopsis lemaneiformis 3 0.7540
Polyamine aminopropyltransferase Q5SK28 SPEE_THET8 Thermus thermophilus 3 0.7538
Polyamine aminopropyltransferase Q5SK28 SPEE_THET8 Thermus thermophilus 3 0.7538
2',3'-cyclic-nucleotide 3'-phosphodiesterase P16330 CN37_MOUSE Mus musculus 2 0.7537
2',3'-cyclic-nucleotide 3'-phosphodiesterase P16330 CN37_MOUSE Mus musculus 2 0.7537
Abscisic acid receptor PYL9 Q84MC7 PYL9_ARATH Arabidopsis thaliana 2 0.7535
Abscisic acid receptor PYL9 Q84MC7 PYL9_ARATH Arabidopsis thaliana 2 0.7535
Mismatch repair endonuclease PMS2 P54278 PMS2_HUMAN Homo sapiens 3 0.7534
Mismatch repair endonuclease PMS2 P54278 PMS2_HUMAN Homo sapiens 3 0.7534
ATP-dependent molecular chaperone HSP82 P02829 HSP82_YEAST Saccharomyces cerevisiae 2 0.7532
ATP-dependent molecular chaperone HSP82 P02829 HSP82_YEAST Saccharomyces cerevisiae 2 0.7532
5'-methylthioadenosine nucleosidase / s-adenosylhomocysteine nucleosidase Q8YBL1 Q8YBL1_BRUME Brucella melitensis biotype 1 3 0.7530
5'-methylthioadenosine nucleosidase / s-adenosylhomocysteine nucleosidase Q8YBL1 Q8YBL1_BRUME Brucella melitensis biotype 1 3 0.7530
ATP-dependent molecular chaperone HSP82 P02829 HSP82_YEAST Saccharomyces cerevisiae 2 0.7527
NADPH-dependent oxidoreductase 2-alkenal reductase Q39172 AER_ARATH Arabidopsis thaliana 2 0.7527
NADPH-dependent oxidoreductase 2-alkenal reductase Q39172 AER_ARATH Arabidopsis thaliana 2 0.7527
ATP-dependent molecular chaperone HSP82 P02829 HSP82_YEAST Saccharomyces cerevisiae 2 0.7527
Genome polyprotein P12823 POLG_DEN2P Dengue virus type 2 3 0.7525
Genome polyprotein P12823 POLG_DEN2P Dengue virus type 2 3 0.7525
Alpha-ketoglutarate-dependent dioxygenase FTO Q9C0B1 FTO_HUMAN Homo sapiens 2 0.7523
Alpha-ketoglutarate-dependent dioxygenase FTO Q9C0B1 FTO_HUMAN Homo sapiens 2 0.7523
Myosin heavy chain kinase A P42527 MHCKA_DICDI Dictyostelium discoideum 3 0.7519
Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial Q8N5Z0 AADAT_HUMAN Homo sapiens 2 0.7519
Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial Q8N5Z0 AADAT_HUMAN Homo sapiens 2 0.7519
Myosin heavy chain kinase A P42527 MHCKA_DICDI Dictyostelium discoideum 3 0.7519
Cyclic AMP receptor protein Q5SID7 CRP_THET8 Thermus thermophilus 2 0.7518
Cyclic AMP receptor protein Q5SID7 CRP_THET8 Thermus thermophilus 2 0.7518
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 Q9Y3Q4 HCN4_HUMAN Homo sapiens 2 0.7517
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 Q9Y3Q4 HCN4_HUMAN Homo sapiens 2 0.7517
Abscisic acid receptor PYL2 O80992 PYL2_ARATH Arabidopsis thaliana 2 0.7515
Abscisic acid receptor PYL2 O80992 PYL2_ARATH Arabidopsis thaliana 2 0.7515
Signaling protein P83820 P83820_THETH Thermus thermophilus 3 0.7513
Signaling protein P83820 P83820_THETH Thermus thermophilus 3 0.7513
Uncharacterized protein MJ0489 Q57913 Y489_METJA Methanocaldococcus jannaschii 3 0.7511
Uncharacterized protein MJ0489 Q57913 Y489_METJA Methanocaldococcus jannaschii 3 0.7511
Mitogen-activated protein kinase kinase kinase 7 O43318 M3K7_HUMAN Homo sapiens 3 0.7506
Mitogen-activated protein kinase kinase kinase 7 O43318 M3K7_HUMAN Homo sapiens 3 0.7506
Nucleoside 2-deoxyribosyltransferase Q8RLY5 Q8RLY5_LACHE Lactobacillus helveticus 2 0.7502
Nucleoside 2-deoxyribosyltransferase Q8RLY5 Q8RLY5_LACHE Lactobacillus helveticus 2 0.7502
Purine nucleoside phosphorylase DeoD-type P0ABP8 DEOD_ECOLI Escherichia coli 2 0.7501
Purine nucleoside phosphorylase DeoD-type P0ABP8 DEOD_ECOLI Escherichia coli 2 0.7501
Pentaerythritol tetranitrate reductase P71278 P71278_ENTCL Enterobacter cloacae 2 0.7499
Nucleoside diphosphate kinase Q5UQL3 NDK_MIMIV Acanthamoeba polyphaga mimivirus 2 0.7499
Pentaerythritol tetranitrate reductase P71278 P71278_ENTCL Enterobacter cloacae 2 0.7499
Queuine tRNA-ribosyltransferase P28720 TGT_ZYMMO Zymomonas mobilis subsp. mobilis 2 0.7499
Purine nucleoside phosphorylase DeoD-type P0ABP9 DEOD_ECO57 Escherichia coli O157:H7 2 0.7499
ATP-dependent protease ATPase subunit HslU P43773 HSLU_HAEIN Haemophilus influenzae 3 0.7499
ATP-dependent protease ATPase subunit HslU P43773 HSLU_HAEIN Haemophilus influenzae 3 0.7499
Purine nucleoside phosphorylase DeoD-type P0ABP9 DEOD_ECO57 Escherichia coli O157:H7 2 0.7499
Queuine tRNA-ribosyltransferase P28720 TGT_ZYMMO Zymomonas mobilis subsp. mobilis 2 0.7499
Nucleoside diphosphate kinase Q5UQL3 NDK_MIMIV Acanthamoeba polyphaga mimivirus 2 0.7499
Ceramide transfer protein Q9Y5P4 CERT_HUMAN Homo sapiens 2 0.7497
Ceramide transfer protein Q9Y5P4 CERT_HUMAN Homo sapiens 2 0.7497
Tyrosine-protein kinase ABL1 P00519 ABL1_HUMAN Homo sapiens 3 0.7494
Tyrosine-protein kinase ABL1 P00519 ABL1_HUMAN Homo sapiens 3 0.7494
Mitogen-activated protein kinase 8 P45983 MK08_HUMAN Homo sapiens 2 0.7494
Nuclear receptor subfamily 4immunitygroup A member 1 P22736 NR4A1_HUMAN Homo sapiens 2 0.7494
Mitogen-activated protein kinase 8 P45983 MK08_HUMAN Homo sapiens 2 0.7494
Nuclear receptor subfamily 4immunitygroup A member 1 P22736 NR4A1_HUMAN Homo sapiens 2 0.7494
Genome polyprotein P29991 POLG_DEN27 Dengue virus type 2 3 0.7491
Genome polyprotein P29991 POLG_DEN27 Dengue virus type 2 3 0.7491
Pentaerythritol tetranitrate reductase P71278 P71278_ENTCL Enterobacter cloacae 2 0.7489
Pentaerythritol tetranitrate reductase P71278 P71278_ENTCL Enterobacter cloacae 2 0.7489
Plasma membrane ATPase Q42932 Q42932_NICPL Nicotiana plumbaginifolia 2 0.7488
Plasma membrane ATPase Q42932 Q42932_NICPL Nicotiana plumbaginifolia 2 0.7488
Beta-galactosidase P00722 BGAL_ECOLI Escherichia coli 3 0.7487
Beta-galactosidase P00722 BGAL_ECOLI Escherichia coli 3 0.7487
Gag-Pol polyprotein P03367 POL_HV1BR Human immunodeficiency virus type 1 group M subtype B 2 0.7486
Gag-Pol polyprotein P03367 POL_HV1BR Human immunodeficiency virus type 1 group M subtype B 2 0.7486
Karilysin D0EM77 KLY_TANFA Tannerella forsythia 2 0.7486
(R)-S-adenosyl-L-methionine hydrolase O58212 O58212_PYRHO Pyrococcus horikoshii OT3 3 0.7486
Karilysin D0EM77 KLY_TANFA Tannerella forsythia 2 0.7486
(R)-S-adenosyl-L-methionine hydrolase O58212 O58212_PYRHO Pyrococcus horikoshii OT3 3 0.7486
Aurora kinase A O14965 AURKA_HUMAN Homo sapiens 3 0.7483
Aurora kinase A O14965 AURKA_HUMAN Homo sapiens 3 0.7483
Serine/threonine-protein kinase 24 Q9Y6E0 STK24_HUMAN Homo sapiens 3 0.7482
Serine/threonine-protein kinase 24 Q9Y6E0 STK24_HUMAN Homo sapiens 3 0.7482
Cyclin-dependent kinase 9 P50750 CDK9_HUMAN Homo sapiens 3 0.7481
Cyclin-dependent kinase 9 P50750 CDK9_HUMAN Homo sapiens 3 0.7481
Flavoredoxin Q72HI0 Q72HI0_THET2 Thermus thermophilus 2 0.7479
Flavoredoxin Q72HI0 Q72HI0_THET2 Thermus thermophilus 2 0.7479
Chaperone protein ClpB Q9RA63 CLPB_THET8 Thermus thermophilus 3 0.7478
Chaperone protein ClpB Q9RA63 CLPB_THET8 Thermus thermophilus 3 0.7478
eIF-2-alpha kinase GCN2 P15442 GCN2_YEAST Saccharomyces cerevisiae 3 0.7477
Mitogen-activated protein kinase 8 P45983 MK08_HUMAN Homo sapiens 2 0.7477
Purine nucleoside phosphorylase DeoD-type O34925 DEOD_BACSU Bacillus subtilis 2 0.7477
eIF-2-alpha kinase GCN2 P15442 GCN2_YEAST Saccharomyces cerevisiae 3 0.7477
Mitogen-activated protein kinase 8 P45983 MK08_HUMAN Homo sapiens 2 0.7477
Purine nucleoside phosphorylase DeoD-type O34925 DEOD_BACSU Bacillus subtilis 2 0.7477
Peripheral plasma membrane protein CASK O14936 CSKP_HUMAN Homo sapiens 3 0.7476
Peripheral plasma membrane protein CASK O14936 CSKP_HUMAN Homo sapiens 3 0.7476
Metallophosphoesterase MPPED2 B1WBP0 MPPD2_RAT Rattus norvegicus 3 0.7473
Metallophosphoesterase MPPED2 B1WBP0 MPPD2_RAT Rattus norvegicus 3 0.7473
Mitogen-activated protein kinase 1 P28482 MK01_HUMAN Homo sapiens 2 0.7471
Mitogen-activated protein kinase 1 P28482 MK01_HUMAN Homo sapiens 2 0.7471
Purine nucleoside phosphorylase Q8I3X4 Q8I3X4_PLAF7 Plasmodium falciparum 2 0.7469
Purine nucleoside phosphorylase Q8I3X4 Q8I3X4_PLAF7 Plasmodium falciparum 2 0.7469
Serine/threonine-protein kinase PLK1 P53350 PLK1_HUMAN Homo sapiens 3 0.7468
Serine/threonine-protein kinase PLK1 P53350 PLK1_HUMAN Homo sapiens 3 0.7468
APH(2'')-Id O68183 O68183_ENTCA Enterococcus casseliflavus 3 0.7467
APH(2'')-Id O68183 O68183_ENTCA Enterococcus casseliflavus 3 0.7467
SRSF protein kinase 1 Q96SB4 SRPK1_HUMAN Homo sapiens 3 0.7467
SRSF protein kinase 1 Q96SB4 SRPK1_HUMAN Homo sapiens 3 0.7467
Aurora kinase A O14965 AURKA_HUMAN Homo sapiens 3 0.7466
Aurora kinase A O14965 AURKA_HUMAN Homo sapiens 3 0.7466
3-oxoacyl-[acyl-carrier-protein] synthase 2 P0AAI5 FABF_ECOLI Escherichia coli 3 0.7465
3-oxoacyl-[acyl-carrier-protein] synthase 2 P0AAI5 FABF_ECOLI Escherichia coli 3 0.7465
5-formaminoimidazole-4-carboxamide-1-(beta)-D-ribofuranosyl 5'-monophosphate synthetase Q8U0R7 PURP_PYRFU Pyrococcus furiosus 3 0.7464
5-formaminoimidazole-4-carboxamide-1-(beta)-D-ribofuranosyl 5'-monophosphate synthetase Q8U0R7 PURP_PYRFU Pyrococcus furiosus 3 0.7464
Prothrombin P00734 THRB_HUMAN Homo sapiens 2 0.7458
Prothrombin P00734 THRB_HUMAN Homo sapiens 2 0.7458
Cytosine-specific methyltransferase Q8EVR5 Q8EVR5_MYCPE Mycoplasma penetrans 3 0.7458
Cytosine-specific methyltransferase Q8EVR5 Q8EVR5_MYCPE Mycoplasma penetrans 3 0.7458
Maltokinase A1TH50 MAK_MYCVP Mycolicibacterium vanbaalenii 3 0.7456
Maltokinase A1TH50 MAK_MYCVP Mycolicibacterium vanbaalenii 3 0.7456
Purine nucleoside phosphorylase DeoD-type Q5EEL8 DEOD_BACCE Bacillus cereus 2 0.7454
Purine nucleoside phosphorylase DeoD-type Q5EEL8 DEOD_BACCE Bacillus cereus 2 0.7454
Purine nucleoside phosphorylase DeoD-type Q5EEL8 DEOD_BACCE Bacillus cereus 2 0.7454
Purine nucleoside phosphorylase DeoD-type Q5EEL8 DEOD_BACCE Bacillus cereus 2 0.7454
Hygromycin-B 4-O-kinase P00557 KHYB_ECOLX Escherichia coli 3 0.7453
Hygromycin-B 4-O-kinase P00557 KHYB_ECOLX Escherichia coli 3 0.7453
Rho-associated protein kinase 1 Q13464 ROCK1_HUMAN Homo sapiens 3 0.7452
Rho-associated protein kinase 1 Q13464 ROCK1_HUMAN Homo sapiens 3 0.7452
Eukaryotic translation initiation factor 2 subunit alpha P20459 IF2A_YEAST Saccharomyces cerevisiae 3 0.7450
Myosin heavy chain kinase A P42527 MHCKA_DICDI Dictyostelium discoideum 3 0.7450
Eukaryotic translation initiation factor 2 subunit alpha P20459 IF2A_YEAST Saccharomyces cerevisiae 3 0.7450
Myosin heavy chain kinase A P42527 MHCKA_DICDI Dictyostelium discoideum 3 0.7450
Phosphatidylinositol 5-phosphate 4-kinase type-2 beta P78356 PI42B_HUMAN Homo sapiens 3 0.7449
Phosphatidylinositol 5-phosphate 4-kinase type-2 beta P78356 PI42B_HUMAN Homo sapiens 3 0.7449
Ephrin type-A receptor 2 P29317 EPHA2_HUMAN Homo sapiens 3 0.7447
Ephrin type-A receptor 2 P29317 EPHA2_HUMAN Homo sapiens 3 0.7447
N-alpha-acetyltransferase 50 Q9GZZ1 NAA50_HUMAN Homo sapiens 3 0.7447
N-alpha-acetyltransferase 50 Q9GZZ1 NAA50_HUMAN Homo sapiens 3 0.7447
Archaeal actin homolog Q9HKL4 ACTH_THEAC Thermoplasma acidophilum 2 0.7445
Archaeal actin homolog Q9HKL4 ACTH_THEAC Thermoplasma acidophilum 2 0.7445
Biotin carboxylase P43873 ACCC_HAEIN Haemophilus influenzae 3 0.7444
Biotin carboxylase P43873 ACCC_HAEIN Haemophilus influenzae 3 0.7444
NAD-capped RNA hydrolase NudC P32664 NUDC_ECOLI Escherichia coli 2 0.7443
Endothiapepsin P11838 CARP_CRYPA Cryphonectria parasitica 2 0.7443
Endothiapepsin P11838 CARP_CRYPA Cryphonectria parasitica 2 0.7443
NAD-capped RNA hydrolase NudC P32664 NUDC_ECOLI Escherichia coli 2 0.7443
Biotin carboxylase P24182 ACCC_ECOLI Escherichia coli 3 0.7442
Biotin carboxylase P24182 ACCC_ECOLI Escherichia coli 3 0.7442
cGMP-dependent 3',5'-cyclic phosphodiesterase O00408 PDE2A_HUMAN Homo sapiens 3 0.7441
Cyclin-dependent kinase 2 P24941 CDK2_HUMAN Homo sapiens 3 0.7441
cGMP-dependent 3',5'-cyclic phosphodiesterase O00408 PDE2A_HUMAN Homo sapiens 3 0.7441
Cyclin-dependent kinase 2 P24941 CDK2_HUMAN Homo sapiens 3 0.7441
Lethal factor P15917 LEF_BACAN Bacillus anthracis 2 0.7440
Lethal factor P15917 LEF_BACAN Bacillus anthracis 2 0.7440
DNA-binding transcriptional dual regulator CRP P0ACJ8 CRP_ECOLI Escherichia coli 2 0.7439
DNA-binding transcriptional dual regulator CRP P0ACJ8 CRP_ECOLI Escherichia coli 2 0.7439
Fibroblast growth factor receptor 2 P21802 FGFR2_HUMAN Homo sapiens 3 0.7439
Fibroblast growth factor receptor 2 P21802 FGFR2_HUMAN Homo sapiens 3 0.7439
Chloramphenicol 3-O phosphotransferase Q56148 CPT_STRVP Streptomyces venezuelae 2 0.7438
Flavin-dependent thymidylate synthase Q9WYT0 THYX_THEMA Thermotoga maritima 2 0.7438
Flavin-dependent thymidylate synthase Q9WYT0 THYX_THEMA Thermotoga maritima 2 0.7438
Chloramphenicol 3-O phosphotransferase Q56148 CPT_STRVP Streptomyces venezuelae 2 0.7438
Fibroblast growth factor receptor 2 P21802 FGFR2_HUMAN Homo sapiens 3 0.7432
Fibroblast growth factor receptor 2 P21802 FGFR2_HUMAN Homo sapiens 3 0.7432
2',3'-cyclic-nucleotide 3'-phosphodiesterase P16330 CN37_MOUSE Mus musculus 2 0.7431
2',3'-cyclic-nucleotide 3'-phosphodiesterase P16330 CN37_MOUSE Mus musculus 2 0.7431
Pteridine reductase 1 Q01782 PTR1_LEIMA Leishmania major 2 0.7430
Ribosyldihydronicotinamide dehydrogenase [quinone] P16083 NQO2_HUMAN Homo sapiens 2 0.7430
Kinesin-like protein KIF11 P52732 KIF11_HUMAN Homo sapiens 2 0.7430
Purine nucleoside phosphorylase P00491 PNPH_HUMAN Homo sapiens 2 0.7430
Pteridine reductase 1 Q01782 PTR1_LEIMA Leishmania major 2 0.7430
Ribosyldihydronicotinamide dehydrogenase [quinone] P16083 NQO2_HUMAN Homo sapiens 2 0.7430
Kinesin-like protein KIF11 P52732 KIF11_HUMAN Homo sapiens 2 0.7430
Purine nucleoside phosphorylase P00491 PNPH_HUMAN Homo sapiens 2 0.7430
Beta-galactosidase P00722 BGAL_ECOLI Escherichia coli 2 0.7429
Beta-galactosidase P00722 BGAL_ECOLI Escherichia coli 2 0.7429
Epidermal growth factor receptor P00533 EGFR_HUMAN Homo sapiens 3 0.7429
Epidermal growth factor receptor P00533 EGFR_HUMAN Homo sapiens 3 0.7429
Cyclin-dependent kinase 9 P50750 CDK9_HUMAN Homo sapiens 3 0.7426
Cyclin-dependent kinase 9 P50750 CDK9_HUMAN Homo sapiens 3 0.7426
tRNA (adenine(9)-N1)-methyltransferase Q4J894 TRM10_SULAC Sulfolobus acidocaldarius 3 0.7425
tRNA (adenine(9)-N1)-methyltransferase Q4J894 TRM10_SULAC Sulfolobus acidocaldarius 3 0.7425
Thiopurine S-methyltransferase O55060 TPMT_MOUSE Mus musculus 3 0.7424
Thiopurine S-methyltransferase O55060 TPMT_MOUSE Mus musculus 3 0.7424
2-phospho-L-lactate transferase Q8PVT6 COFD_METMA Methanosarcina mazei 2 0.7424
2-phospho-L-lactate transferase Q8PVT6 COFD_METMA Methanosarcina mazei 2 0.7424
Geranyl diphosphate 2-C-methyltransferase D3KYU3 GPPMT_STRLS Streptomyces lasalocidi 3 0.7423
Geranyl diphosphate 2-C-methyltransferase D3KYU3 GPPMT_STRLS Streptomyces lasalocidi 3 0.7423
Photosynthetic reaction center cytochrome c subunit P07173 CYCR_BLAVI Blastochloris viridis 2 0.7422
Photosynthetic reaction center cytochrome c subunit P07173 CYCR_BLAVI Blastochloris viridis 2 0.7422
DNA adenine methylase P0AEE8 DMA_ECOLI Escherichia coli 3 0.7418
DNA adenine methylase P0AEE8 DMA_ECOLI Escherichia coli 3 0.7418
Probable enoyl-CoA hydratase EchA8 P9WNN9 ECHA8_MYCTU Mycobacterium tuberculosis 3 0.7418
Probable enoyl-CoA hydratase EchA8 P9WNN9 ECHA8_MYCTU Mycobacterium tuberculosis 3 0.7418
Serine/threonine-protein kinase CtkA Q9ZKJ5 CTKA_HELPJ Helicobacter pylori 3 0.7417
Serine/threonine-protein kinase CtkA Q9ZKJ5 CTKA_HELPJ Helicobacter pylori 3 0.7417
Quorum-sensing transcriptional activator Q8XBD0 Q8XBD0_ECO57 Escherichia coli O157:H7 2 0.7416
Quorum-sensing transcriptional activator Q8XBD0 Q8XBD0_ECO57 Escherichia coli O157:H7 2 0.7416
3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase O33877 FABA_PSEAE Pseudomonas aeruginosa 2 0.7414
Prolyl tripeptidyl peptidase Q7MUW6 PTP_PORGI Porphyromonas gingivalis 2 0.7414
3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase O33877 FABA_PSEAE Pseudomonas aeruginosa 2 0.7414
Prolyl tripeptidyl peptidase Q7MUW6 PTP_PORGI Porphyromonas gingivalis 2 0.7414
Serine/threonine-protein kinase RIO1 Q9BRS2 RIOK1_HUMAN Homo sapiens 3 0.7414
Aurora kinase A O14965 AURKA_HUMAN Homo sapiens 3 0.7414
Aurora kinase A O14965 AURKA_HUMAN Homo sapiens 3 0.7414
Serine/threonine-protein kinase RIO1 Q9BRS2 RIOK1_HUMAN Homo sapiens 3 0.7414
Tyrosine-protein kinase receptor TYRO3 P55144 TYRO3_MOUSE Mus musculus 3 0.7413
Tyrosine-protein kinase receptor TYRO3 P55144 TYRO3_MOUSE Mus musculus 3 0.7413
Serine/threonine-protein kinase Chk1 O14757 CHK1_HUMAN Homo sapiens 3 0.7409
Serine/threonine-protein kinase Chk1 O14757 CHK1_HUMAN Homo sapiens 3 0.7409
Rhodopsin kinase GRK1 P28327 GRK1_BOVIN Bos taurus 3 0.7407
Rhodopsin kinase GRK1 P28327 GRK1_BOVIN Bos taurus 3 0.7407
DNA polymerase III subunit epsilon P03007 DPO3E_ECOLI Escherichia coli 2 0.7406
DNA polymerase III subunit epsilon P03007 DPO3E_ECOLI Escherichia coli 2 0.7406
Genome polyprotein P12823 POLG_DEN2P Dengue virus type 2 3 0.7404
Genome polyprotein P12823 POLG_DEN2P Dengue virus type 2 3 0.7404
Pantothenate synthetase P9WIL5 PANC_MYCTU Mycobacterium tuberculosis 2 0.7403
Pantothenate synthetase P9WIL5 PANC_MYCTU Mycobacterium tuberculosis 2 0.7403
Methionine aminopeptidase 2 P9WK19 MAP12_MYCTU Mycobacterium tuberculosis 2 0.7398
Tryptophan synthase alpha chain P00929 TRPA_SALTY Salmonella typhimurium 2 0.7398
Tryptophan synthase alpha chain P00929 TRPA_SALTY Salmonella typhimurium 2 0.7398
Methionine aminopeptidase 2 P9WK19 MAP12_MYCTU Mycobacterium tuberculosis 2 0.7398
Peripheral plasma membrane protein CASK O14936 CSKP_HUMAN Homo sapiens 3 0.7396
Cyclin-dependent kinase 2 P24941 CDK2_HUMAN Homo sapiens 2 0.7396
2-phospho-L-lactate transferase Q8PVT6 COFD_METMA Methanosarcina mazei 2 0.7396
Peripheral plasma membrane protein CASK O14936 CSKP_HUMAN Homo sapiens 3 0.7396
Psp operon transcriptional activator P37344 PSPF_ECOLI Escherichia coli 3 0.7396
Cyclin-dependent kinase 2 P24941 CDK2_HUMAN Homo sapiens 2 0.7396
2-phospho-L-lactate transferase Q8PVT6 COFD_METMA Methanosarcina mazei 2 0.7396
Psp operon transcriptional activator P37344 PSPF_ECOLI Escherichia coli 3 0.7396
Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 Q9Y3Z3 SAMH1_HUMAN Homo sapiens 2 0.7395
Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 Q9Y3Z3 SAMH1_HUMAN Homo sapiens 2 0.7395
Death-associated protein kinase 1 P53355 DAPK1_HUMAN Homo sapiens 3 0.7391
Death-associated protein kinase 1 P53355 DAPK1_HUMAN Homo sapiens 3 0.7391
Glutathione S-transferase Q8ILQ7 GST_PLAFA Plasmodium falciparum 3 0.7391
Glutathione S-transferase Q8ILQ7 GST_PLAFA Plasmodium falciparum 3 0.7391
Purine nucleoside phosphorylase DeoD-type P0ABP9 DEOD_ECO57 Escherichia coli O157:H7 2 0.7390
Purine nucleoside phosphorylase DeoD-type P0ABP9 DEOD_ECO57 Escherichia coli O157:H7 2 0.7390
Type IV / VI secretion system DotU domain-containing protein Q9KN50 Q9KN50_VIBCH Vibrio cholerae serotype O1 2 0.7389
Type IV / VI secretion system DotU domain-containing protein Q9KN50 Q9KN50_VIBCH Vibrio cholerae serotype O1 2 0.7389
Serine/threonine-protein kinase CtkA Q9ZKJ5 CTKA_HELPJ Helicobacter pylori 3 0.7387
Serine/threonine-protein kinase CtkA Q9ZKJ5 CTKA_HELPJ Helicobacter pylori 3 0.7387
F420-dependent methylenetetrahydromethanopterin dehydrogenase P94951 MTD_METKA Methanopyrus kandleri 2 0.7384
F420-dependent methylenetetrahydromethanopterin dehydrogenase P94951 MTD_METKA Methanopyrus kandleri 2 0.7384
GTP 3',8-cyclase P69848 MOAA_STAA8 Staphylococcus aureus 3 0.7384
GTP 3',8-cyclase P69848 MOAA_STAA8 Staphylococcus aureus 3 0.7384
Ribosomal protein S6 kinase alpha-1 Q15418 KS6A1_HUMAN Homo sapiens 3 0.7382
Kinesin-like protein KIF11 P52732 KIF11_HUMAN Homo sapiens 2 0.7382
Ribosomal protein S6 kinase alpha-1 Q15418 KS6A1_HUMAN Homo sapiens 3 0.7382
Kinesin-like protein KIF11 P52732 KIF11_HUMAN Homo sapiens 2 0.7382
Glycogen synthase kinase-3 beta P49841 GSK3B_HUMAN Homo sapiens 2 0.7381
Mitogen-activated protein kinase 8 P45983 MK08_HUMAN Homo sapiens 2 0.7381
Glycogen synthase kinase-3 beta P49841 GSK3B_HUMAN Homo sapiens 2 0.7381
Mitogen-activated protein kinase 8 P45983 MK08_HUMAN Homo sapiens 2 0.7381
Ribosomal protein L11 methyltransferase Q84BQ9 PRMA_THET8 Thermus thermophilus 2 0.7379
Ribosomal protein L11 methyltransferase Q84BQ9 PRMA_THET8 Thermus thermophilus 2 0.7379
Stromelysin-1 P08254 MMP3_HUMAN Homo sapiens 2 0.7378
Disintegrin and metalloproteinase domain-containing protein 17 P78536 ADA17_HUMAN Homo sapiens 2 0.7378
Stromelysin-1 P08254 MMP3_HUMAN Homo sapiens 2 0.7378
Disintegrin and metalloproteinase domain-containing protein 17 P78536 ADA17_HUMAN Homo sapiens 2 0.7378
Photosynthetic reaction center cytochrome c subunit P07173 CYCR_BLAVI Blastochloris viridis 2 0.7377
Photosynthetic reaction center cytochrome c subunit P07173 CYCR_BLAVI Blastochloris viridis 2 0.7377
Mitogen-activated protein kinase kinase kinase 21 Q5TCX8 M3K21_HUMAN Homo sapiens 3 0.7376
RNA 2'-O ribose methyltransferase Q5SLL8 Q5SLL8_THET8 Thermus thermophilus 3 0.7376
RNA 2'-O ribose methyltransferase Q5SLL8 Q5SLL8_THET8 Thermus thermophilus 3 0.7376
Mitogen-activated protein kinase kinase kinase 21 Q5TCX8 M3K21_HUMAN Homo sapiens 3 0.7376
N-terminal acetyltransferase A complex subunit NAT1 P12945 NAT1_YEAST Saccharomyces cerevisiae 2 0.7375
Rhodopsin kinase GRK1 P28327 GRK1_BOVIN Bos taurus 3 0.7375
N-terminal acetyltransferase A complex subunit NAT1 P12945 NAT1_YEAST Saccharomyces cerevisiae 2 0.7375
Rhodopsin kinase GRK1 P28327 GRK1_BOVIN Bos taurus 3 0.7375
Phenylpyruvate C(3)-methyltransferase Q643C8 MPPJ_STRHY Streptomyces hygroscopicus 2 0.7373
Phenylpyruvate C(3)-methyltransferase Q643C8 MPPJ_STRHY Streptomyces hygroscopicus 2 0.7373
Lactotransferrin P24627 TRFL_BOVIN Bos taurus 2 0.7372
cAMP-dependent protein kinase type II-beta regulatory subunit P12369 KAP3_RAT Rattus norvegicus 2 0.7372
Lactotransferrin P24627 TRFL_BOVIN Bos taurus 2 0.7372
cAMP-dependent protein kinase type II-beta regulatory subunit P12369 KAP3_RAT Rattus norvegicus 2 0.7372
Metallophosphoesterase MPPED2 B1WBP0 MPPD2_RAT Rattus norvegicus 3 0.7371
Biflaviolin synthase CYP158A2 Q9FCA6 C1582_STRCO Streptomyces coelicolor / M145) 2 0.7371
Metallophosphoesterase MPPED2 B1WBP0 MPPD2_RAT Rattus norvegicus 3 0.7371
Biflaviolin synthase CYP158A2 Q9FCA6 C1582_STRCO Streptomyces coelicolor / M145) 2 0.7371
Biflaviolin synthase CYP158A1 Q9KZF5 C1581_STRCO Streptomyces coelicolor / M145) 2 0.7370
Putative aminoglycoside phosphotransferase P9WI99 Y3168_MYCTU Mycobacterium tuberculosis 3 0.7370
Putative aminoglycoside phosphotransferase P9WI99 Y3168_MYCTU Mycobacterium tuberculosis 3 0.7370
Biflaviolin synthase CYP158A1 Q9KZF5 C1581_STRCO Streptomyces coelicolor / M145) 2 0.7370
5-methylthioadenosine/S-adenosylhomocysteine deaminase Q7NZ90 Q7NZ90_CHRVO Chromobacterium violaceum 2 0.7369
Lactoperoxidase A5JUY8 PERL_BUBBU Bubalus bubalis 3 0.7369
5-methylthioadenosine/S-adenosylhomocysteine deaminase Q7NZ90 Q7NZ90_CHRVO Chromobacterium violaceum 2 0.7369
Lactoperoxidase A5JUY8 PERL_BUBBU Bubalus bubalis 3 0.7369
Prothrombin P00734 THRB_HUMAN Homo sapiens 2 0.7367
Prothrombin P00734 THRB_HUMAN Homo sapiens 2 0.7367
Endothiapepsin P11838 CARP_CRYPA Cryphonectria parasitica 2 0.7366
Endothiapepsin P11838 CARP_CRYPA Cryphonectria parasitica 2 0.7366
Threonine synthase 1, chloroplastic Q9S7B5 THRC1_ARATH Arabidopsis thaliana 2 0.7360
Threonine synthase 1, chloroplastic Q9S7B5 THRC1_ARATH Arabidopsis thaliana 2 0.7360
Hygromycin-B 4-O-kinase P00557 KHYB_ECOLX Escherichia coli 3 0.7359
Bifunctional epoxide hydrolase 2 P34913 HYES_HUMAN Homo sapiens 2 0.7359
Bifunctional epoxide hydrolase 2 P34913 HYES_HUMAN Homo sapiens 2 0.7359
Hygromycin-B 4-O-kinase P00557 KHYB_ECOLX Escherichia coli 3 0.7359
1-deoxy-D-xylulose 5-phosphate reductoisomerase, apicoplastic O96693 DXR_PLAFX Plasmodium falciparum 2 0.7355
1-deoxy-D-xylulose 5-phosphate reductoisomerase, apicoplastic O96693 DXR_PLAFX Plasmodium falciparum 2 0.7355
Gag-Pol polyprotein P05896 POL_SIVM1 Simian immunodeficiency virus 3 0.7350
Gag-Pol polyprotein P05896 POL_SIVM1 Simian immunodeficiency virus 3 0.7350
Metallo-beta-lactamase type 2 P26918 BLAB_AERHY Aeromonas hydrophila 2 0.7349
Metallo-beta-lactamase type 2 P26918 BLAB_AERHY Aeromonas hydrophila 2 0.7349
Transcriptional activator, LuxR/UhpA family of regulators Q7NQP7 Q7NQP7_CHRVO Chromobacterium violaceum 2 0.7348
Transcriptional activator, LuxR/UhpA family of regulators Q7NQP7 Q7NQP7_CHRVO Chromobacterium violaceum 2 0.7348
Biotin carboxylase P43873 ACCC_HAEIN Haemophilus influenzae 3 0.7346
Biotin carboxylase P43873 ACCC_HAEIN Haemophilus influenzae 3 0.7346
Glycoside Hydrolase Family 13 Q65MI2 Q65MI2_BACLD Bacillus licheniformis 2 0.7345
Glycoside Hydrolase Family 13 Q65MI2 Q65MI2_BACLD Bacillus licheniformis 2 0.7345
Queuine tRNA-ribosyltransferase P28720 TGT_ZYMMO Zymomonas mobilis subsp. mobilis 2 0.7344
Queuine tRNA-ribosyltransferase P28720 TGT_ZYMMO Zymomonas mobilis subsp. mobilis 2 0.7344
Queuine tRNA-ribosyltransferase P28720 TGT_ZYMMO Zymomonas mobilis subsp. mobilis 2 0.7344
Prothrombin P00734 THRB_HUMAN Homo sapiens 2 0.7344
Prothrombin P00734 THRB_HUMAN Homo sapiens 2 0.7344
Queuine tRNA-ribosyltransferase P28720 TGT_ZYMMO Zymomonas mobilis subsp. mobilis 2 0.7344
Tryptophan synthase alpha chain P00929 TRPA_SALTY Salmonella typhimurium 2 0.7340
Tryptophan synthase alpha chain P00929 TRPA_SALTY Salmonella typhimurium 2 0.7340
Fibroblast growth factor receptor 2 P21802 FGFR2_HUMAN Homo sapiens 3 0.7339
Fibroblast growth factor receptor 2 P21802 FGFR2_HUMAN Homo sapiens 3 0.7339
Alanine racemase Q180W0 Q180W0_CLOD6 Clostridioides difficile 2 0.7337
Alanine racemase Q180W0 Q180W0_CLOD6 Clostridioides difficile 2 0.7337
Aldo-keto reductase family 1 member B1 P15121 ALDR_HUMAN Homo sapiens 2 0.7335
Aldo-keto reductase family 1 member B1 P15121 ALDR_HUMAN Homo sapiens 2 0.7335
2',3'-cyclic-nucleotide 3'-phosphodiesterase P16330 CN37_MOUSE Mus musculus 2 0.7333
BMP-2-inducible protein kinase Q9NSY1 BMP2K_HUMAN Homo sapiens 2 0.7333
2',3'-cyclic-nucleotide 3'-phosphodiesterase P16330 CN37_MOUSE Mus musculus 2 0.7333
BMP-2-inducible protein kinase Q9NSY1 BMP2K_HUMAN Homo sapiens 2 0.7333
Myosin heavy chain kinase A P42527 MHCKA_DICDI Dictyostelium discoideum 3 0.7332
Myosin heavy chain kinase A P42527 MHCKA_DICDI Dictyostelium discoideum 3 0.7332
11-beta-hydroxysteroid dehydrogenase 1 P28845 DHI1_HUMAN Homo sapiens 2 0.7331
11-beta-hydroxysteroid dehydrogenase 1 P28845 DHI1_HUMAN Homo sapiens 2 0.7331
5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase 1 O50008 METE1_ARATH Arabidopsis thaliana 2 0.7326
5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase 1 O50008 METE1_ARATH Arabidopsis thaliana 2 0.7326
Heat shock protein HSP 90-alpha P07900 HS90A_HUMAN Homo sapiens 2 0.7325
3-oxoacyl-[acyl-carrier-protein] synthase 1 Q2YQQ9 Q2YQQ9_BRUA2 Brucella abortus 3 0.7325
Heat shock protein HSP 90-alpha P07900 HS90A_HUMAN Homo sapiens 2 0.7325
Tryptophan synthase alpha chain P00929 TRPA_SALTY Salmonella typhimurium 2 0.7325
3-oxoacyl-[acyl-carrier-protein] synthase 1 Q2YQQ9 Q2YQQ9_BRUA2 Brucella abortus 3 0.7325
Tryptophan synthase alpha chain P00929 TRPA_SALTY Salmonella typhimurium 2 0.7325
11-beta-hydroxysteroid dehydrogenase 1 P28845 DHI1_HUMAN Homo sapiens 2 0.7322
11-beta-hydroxysteroid dehydrogenase 1 P28845 DHI1_HUMAN Homo sapiens 2 0.7322
cAMP-dependent protein kinase type I-alpha regulatory subunit P00514 KAP0_BOVIN Bos taurus 2 0.7321
cAMP-dependent protein kinase type I-alpha regulatory subunit P00514 KAP0_BOVIN Bos taurus 2 0.7321
Biotin carboxylase P24182 ACCC_ECOLI Escherichia coli 3 0.7316
Biotin carboxylase P24182 ACCC_ECOLI Escherichia coli 3 0.7316
1-deoxy-D-xylulose 5-phosphate reductoisomerase P45568 DXR_ECOLI Escherichia coli 2 0.7315
1-deoxy-D-xylulose 5-phosphate reductoisomerase P45568 DXR_ECOLI Escherichia coli 2 0.7315
Metallophosphoesterase A3DJ38 A3DJ38_HUNT2 Clostridium thermocellum 2 0.7314
DNA adenine methylase P0AEE8 DMA_ECOLI Escherichia coli 3 0.7314
DNA adenine methylase P0AEE8 DMA_ECOLI Escherichia coli 3 0.7314
Metallophosphoesterase A3DJ38 A3DJ38_HUNT2 Clostridium thermocellum 2 0.7314
Kinesin-like protein KIF11 P52732 KIF11_HUMAN Homo sapiens 2 0.7311
Chloramphenicol 3-O phosphotransferase Q56148 CPT_STRVP Streptomyces venezuelae 2 0.7311
Ras-related protein Ral-B P11234 RALB_HUMAN Homo sapiens 2 0.7311
Kinesin-like protein KIF11 P52732 KIF11_HUMAN Homo sapiens 2 0.7311
Ras-related protein Ral-B P11234 RALB_HUMAN Homo sapiens 2 0.7311
Chloramphenicol 3-O phosphotransferase Q56148 CPT_STRVP Streptomyces venezuelae 2 0.7311
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform P48736 PK3CG_HUMAN Homo sapiens 2 0.7310
Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 Q9Y3Z3 SAMH1_HUMAN Homo sapiens 2 0.7310
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform P48736 PK3CG_HUMAN Homo sapiens 2 0.7310
Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 Q9Y3Z3 SAMH1_HUMAN Homo sapiens 2 0.7310
ATP-dependent molecular chaperone HSP82 P02829 HSP82_YEAST Saccharomyces cerevisiae 2 0.7310
ATP-dependent molecular chaperone HSP82 P02829 HSP82_YEAST Saccharomyces cerevisiae 2 0.7310
S-methyl-5'-thioadenosine phosphorylase Q97W94 MTAP_SACS2 Saccharolobus solfataricus 2 0.7308
Aminopeptidase N P15145 AMPN_PIG Sus scrofa 2 0.7308
S-methyl-5'-thioadenosine phosphorylase Q97W94 MTAP_SACS2 Saccharolobus solfataricus 2 0.7308
Aminopeptidase N P15145 AMPN_PIG Sus scrofa 2 0.7308
chitinase B0Y2Y2 B0Y2Y2_ASPFC Aspergillus fumigatus 3 0.7305
chitinase B0Y2Y2 B0Y2Y2_ASPFC Aspergillus fumigatus 3 0.7305
Prothrombin P00734 THRB_HUMAN Homo sapiens 2 0.7302
Prothrombin P00734 THRB_HUMAN Homo sapiens 2 0.7302
Serine/threonine-protein kinase Chk2 O96017 CHK2_HUMAN Homo sapiens 2 0.7301
Putative FAD-dependent oxygenase EncM Q9KHK2 Q9KHK2_9ACTN Streptomyces maritimus 2 0.7301
Serine/threonine-protein kinase Chk2 O96017 CHK2_HUMAN Homo sapiens 2 0.7301
2',3'-cyclic-nucleotide 3'-phosphodiesterase P16330 CN37_MOUSE Mus musculus 2 0.7301
2',3'-cyclic-nucleotide 3'-phosphodiesterase P16330 CN37_MOUSE Mus musculus 2 0.7301
Putative FAD-dependent oxygenase EncM Q9KHK2 Q9KHK2_9ACTN Streptomyces maritimus 2 0.7301
Activated CDC42 kinase 1 Q07912 ACK1_HUMAN Homo sapiens 3 0.7298
Cytochrome P450 2A6 P11509 CP2A6_HUMAN Homo sapiens 2 0.7298
Activated CDC42 kinase 1 Q07912 ACK1_HUMAN Homo sapiens 3 0.7298
Cytochrome P450 2A6 P11509 CP2A6_HUMAN Homo sapiens 2 0.7298
Bifunctional dihydrofolate reductase-thymidylate synthase A7UD81 A7UD81_PLAFA Plasmodium falciparum 2 0.7295
Bifunctional dihydrofolate reductase-thymidylate synthase A7UD81 A7UD81_PLAFA Plasmodium falciparum 2 0.7295
Catalase-peroxidase Q3JNW6 KATG_BURP1 Burkholderia pseudomallei 2 0.7294
Catalase-peroxidase Q3JNW6 KATG_BURP1 Burkholderia pseudomallei 2 0.7294
Norsolorinic acid synthase Q12053 AFLC_ASPPU Aspergillus parasiticus 2 0.7294
Norsolorinic acid synthase Q12053 AFLC_ASPPU Aspergillus parasiticus 2 0.7294
L-lactate dehydrogenase A chain P13491 LDHA_RABIT Oryctolagus cuniculus 2 0.7286
L-lactate dehydrogenase A chain P13491 LDHA_RABIT Oryctolagus cuniculus 2 0.7286
2',3'-cyclic-nucleotide 3'-phosphodiesterase P16330 CN37_MOUSE Mus musculus 2 0.7283
Pyridoxal kinase O00764 PDXK_HUMAN Homo sapiens 2 0.7283
Pyridoxal kinase O00764 PDXK_HUMAN Homo sapiens 2 0.7283
2',3'-cyclic-nucleotide 3'-phosphodiesterase P16330 CN37_MOUSE Mus musculus 2 0.7283
2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate hydrolase P47229 BPHD_PARXL Paraburkholderia xenovorans 2 0.7281
Metallo-beta-lactamase type 2 C7C422 BLAN1_KLEPN Klebsiella pneumoniae 2 0.7281
2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate hydrolase P47229 BPHD_PARXL Paraburkholderia xenovorans 2 0.7281
Metallo-beta-lactamase type 2 C7C422 BLAN1_KLEPN Klebsiella pneumoniae 2 0.7281
Ribosome-inactivating protein 3 P25891 RIP3_MAIZE Zea mays 2 0.7277
Ribosome-inactivating protein 3 P25891 RIP3_MAIZE Zea mays 2 0.7277
DNA-directed DNA polymerase Q38087 DPOL_BPR69 Escherichia phage RB69 2 0.7275
DNA-directed DNA polymerase Q38087 DPOL_BPR69 Escherichia phage RB69 2 0.7275
Single-stranded-DNA-specific exonuclease RecJ D0EM60 D0EM60_DEIRD Deinococcus radiodurans 2 0.7274
Ribonuclease J Q72JJ7 RNJ_THET2 Thermus thermophilus 2 0.7274
Pteridine reductase 1 Q01782 PTR1_LEIMA Leishmania major 2 0.7274
Single-stranded-DNA-specific exonuclease RecJ D0EM60 D0EM60_DEIRD Deinococcus radiodurans 2 0.7274
Pteridine reductase 1 Q01782 PTR1_LEIMA Leishmania major 2 0.7274
Ribonuclease J Q72JJ7 RNJ_THET2 Thermus thermophilus 2 0.7274
Cyclin-dependent kinase 2 P24941 CDK2_HUMAN Homo sapiens 2 0.7273
Cyclin-dependent kinase 2 P24941 CDK2_HUMAN Homo sapiens 2 0.7273
Catechol O-methyltransferase P22734 COMT_RAT Rattus norvegicus 2 0.7272
Biflaviolin synthase CYP158A2 Q9FCA6 C1582_STRCO Streptomyces coelicolor / M145) 2 0.7272
Biflaviolin synthase CYP158A2 Q9FCA6 C1582_STRCO Streptomyces coelicolor / M145) 2 0.7272
Catechol O-methyltransferase P22734 COMT_RAT Rattus norvegicus 2 0.7272
Bifunctional dihydrofolate reductase-thymidylate synthase A7UD81 A7UD81_PLAFA Plasmodium falciparum 2 0.7268
Bifunctional dihydrofolate reductase-thymidylate synthase A7UD81 A7UD81_PLAFA Plasmodium falciparum 2 0.7268
Prothrombin P00734 THRB_HUMAN Homo sapiens 2 0.7267
Prothrombin P00734 THRB_HUMAN Homo sapiens 2 0.7267
VioE domain-containing protein Q7NSZ5 Q7NSZ5_CHRVO Chromobacterium violaceum 2 0.7264
VioE domain-containing protein Q7NSZ5 Q7NSZ5_CHRVO Chromobacterium violaceum 2 0.7264
3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase P19992 HSD_STREX Streptomyces exfoliatus 2 0.7263
3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase P19992 HSD_STREX Streptomyces exfoliatus 2 0.7263
Muconolactone Delta-isomerase Q8G9L0 Q8G9L0_RHOOP Rhodococcus opacus 2 0.7261
Catechol O-methyltransferase P22734 COMT_RAT Rattus norvegicus 2 0.7261
Thiazole tautomerase P25053 TENI_BACSU Bacillus subtilis 2 0.7261
Catechol O-methyltransferase P22734 COMT_RAT Rattus norvegicus 2 0.7261
Thiazole tautomerase P25053 TENI_BACSU Bacillus subtilis 2 0.7261
Muconolactone Delta-isomerase Q8G9L0 Q8G9L0_RHOOP Rhodococcus opacus 2 0.7261
D-alanyl-D-alanine carboxypeptidase P15555 DAC_STRSR Streptomyces sp 2 0.7259
D-alanyl-D-alanine carboxypeptidase P15555 DAC_STRSR Streptomyces sp 2 0.7259
2',3'-cyclic-nucleotide 3'-phosphodiesterase P16330 CN37_MOUSE Mus musculus 2 0.7257
Avidin P02701 AVID_CHICK Gallus gallus 3 0.7257
Caffeoyl-CoA O-methyltransferase Q40313 CAMT_MEDSA Medicago sativa 3 0.7257
2',3'-cyclic-nucleotide 3'-phosphodiesterase P16330 CN37_MOUSE Mus musculus 2 0.7257
Avidin P02701 AVID_CHICK Gallus gallus 3 0.7257
Caffeoyl-CoA O-methyltransferase Q40313 CAMT_MEDSA Medicago sativa 3 0.7257
Ribonuclease 4 P15468 RNAS4_PIG Sus scrofa 2 0.7256
Ribonuclease 4 P15468 RNAS4_PIG Sus scrofa 2 0.7256
2',3'-cyclic-nucleotide 3'-phosphodiesterase P16330 CN37_MOUSE Mus musculus 2 0.7255
2',3'-cyclic-nucleotide 3'-phosphodiesterase P16330 CN37_MOUSE Mus musculus 2 0.7255
Bifunctional dihydrofolate reductase-thymidylate synthase Q27793 DRTS_TRYCR Trypanosoma cruzi 2 0.7254
Succinyl-CoA:acetate CoA-transferase B3EY95 SCACT_ACEAC Acetobacter aceti 2 0.7254
Bifunctional dihydrofolate reductase-thymidylate synthase Q27793 DRTS_TRYCR Trypanosoma cruzi 2 0.7254
Succinyl-CoA:acetate CoA-transferase B3EY95 SCACT_ACEAC Acetobacter aceti 2 0.7254
L-seryl-tRNA(Sec) kinase Q58933 PSTK_METJA Methanocaldococcus jannaschii 2 0.7254
L-seryl-tRNA(Sec) kinase Q58933 PSTK_METJA Methanocaldococcus jannaschii 2 0.7254
Phospholipase A2 P00593 PA21B_BOVIN Bos taurus 2 0.7253
Phospholipase A2 P00593 PA21B_BOVIN Bos taurus 2 0.7253
Class B acid phosphatase P0AE22 APHA_ECOLI Escherichia coli 2 0.7252
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A Q9Y233 PDE10_HUMAN Homo sapiens 2 0.7252
Carbonic anhydrase 2 P00918 CAH2_HUMAN Homo sapiens 2 0.7252
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A Q9Y233 PDE10_HUMAN Homo sapiens 2 0.7252
Class B acid phosphatase P0AE22 APHA_ECOLI Escherichia coli 2 0.7252
Carbonic anhydrase 2 P00918 CAH2_HUMAN Homo sapiens 2 0.7252
Glutamate receptor 2 P42262 GRIA2_HUMAN Homo sapiens 2 0.7250
Glutamate receptor 2 P42262 GRIA2_HUMAN Homo sapiens 2 0.7250
Heat shock protein HSP 90-alpha P07900 HS90A_HUMAN Homo sapiens 2 0.7249
Heat shock protein HSP 90-alpha P07900 HS90A_HUMAN Homo sapiens 2 0.7249
Repressor protein Q7X0D9 Q7X0D9_ACIAD Acinetobacter baylyi 2 0.7248
Beta-1 adrenergic receptor P07700 ADRB1_MELGA Meleagris gallopavo 2 0.7248
Repressor protein Q7X0D9 Q7X0D9_ACIAD Acinetobacter baylyi 2 0.7248
Beta-1 adrenergic receptor P07700 ADRB1_MELGA Meleagris gallopavo 2 0.7248
Avidin P02701 AVID_CHICK Gallus gallus 3 0.7247
Cytochrome b-c1 complex subunit 1, mitochondrial P31800 QCR1_BOVIN Bos taurus 3 0.7247
Avidin P02701 AVID_CHICK Gallus gallus 3 0.7247
Cytochrome b-c1 complex subunit 1, mitochondrial P31800 QCR1_BOVIN Bos taurus 3 0.7247
Queuine tRNA-ribosyltransferase P28720 TGT_ZYMMO Zymomonas mobilis subsp. mobilis 2 0.7246
Queuine tRNA-ribosyltransferase P28720 TGT_ZYMMO Zymomonas mobilis subsp. mobilis 2 0.7246
Nucleoside diphosphate kinase P15266 NDK_MYXXA Myxococcus xanthus 2 0.7241
Nucleoside diphosphate kinase P15266 NDK_MYXXA Myxococcus xanthus 2 0.7241
1-deoxy-D-xylulose 5-phosphate reductoisomerase P45568 DXR_ECOLI Escherichia coli 2 0.7238
mRNA cleavage and polyadenylation factor CLP1 Q08685 CLP1_YEAST Saccharomyces cerevisiae 2 0.7238
mRNA cleavage and polyadenylation factor CLP1 Q08685 CLP1_YEAST Saccharomyces cerevisiae 2 0.7238
1-deoxy-D-xylulose 5-phosphate reductoisomerase P45568 DXR_ECOLI Escherichia coli 2 0.7238
Alcohol dehydrogenase E chain P00327 ADH1E_HORSE Equus caballus 2 0.7232
Alcohol dehydrogenase E chain P00327 ADH1E_HORSE Equus caballus 2 0.7232
Liver carboxylesterase 1 P23141 EST1_HUMAN Homo sapiens 2 0.7231
Reaction center protein L chain P0C0Y7 RCEH_RHOSH Rhodobacter sphaeroides 2 0.7231
Liver carboxylesterase 1 P23141 EST1_HUMAN Homo sapiens 2 0.7231
Reaction center protein L chain P0C0Y7 RCEH_RHOSH Rhodobacter sphaeroides 2 0.7231
Prothrombin P00734 THRB_HUMAN Homo sapiens 2 0.7230
Prothrombin P00734 THRB_HUMAN Homo sapiens 2 0.7230
D-cysteine desulfhydrase Q8ZNT7 DCYD_SALTY Salmonella typhimurium 2 0.7226
D-cysteine desulfhydrase Q8ZNT7 DCYD_SALTY Salmonella typhimurium 2 0.7226
Methionine aminopeptidase P0AE18 MAP1_ECOLI Escherichia coli 2 0.7224
Methionine aminopeptidase P0AE18 MAP1_ECOLI Escherichia coli 2 0.7224
Mandelate racemase P11444 MANR_PSEPU Pseudomonas putida 2 0.7221
Mandelate racemase P11444 MANR_PSEPU Pseudomonas putida 2 0.7221
Uncharacterized protein Q46E79 Q46E79_METBF Methanosarcina barkeri 3 0.7220
Uncharacterized protein Q46E79 Q46E79_METBF Methanosarcina barkeri 3 0.7220
Alpha/beta hydrolase fold A5VAT9 A5VAT9_SPHWW Sphingomonas wittichii 2 0.7218
Alpha/beta hydrolase fold A5VAT9 A5VAT9_SPHWW Sphingomonas wittichii 2 0.7218
Proton-gated ion channel Q7NDN8 GLIC_GLOVI Gloeobacter violaceus 2 0.7217
Proton-gated ion channel Q7NDN8 GLIC_GLOVI Gloeobacter violaceus 2 0.7217
L-lactate dehydrogenase A chain P04642 LDHA_RAT Rattus norvegicus 3 0.7216
L-lactate dehydrogenase A chain P04642 LDHA_RAT Rattus norvegicus 3 0.7216
Prothrombin P00734 THRB_HUMAN Homo sapiens 2 0.7214
Prothrombin P00734 THRB_HUMAN Homo sapiens 2 0.7214
Inosine-5'-monophosphate dehydrogenase P50097 IMDH_TRIFO Tritrichomonas foetus 2 0.7209
Nucleoside diphosphate kinase A5J299 A5J299_PENVA Penaeus vannamei 2 0.7209
Inosine-5'-monophosphate dehydrogenase P50097 IMDH_TRIFO Tritrichomonas foetus 2 0.7209
Nucleoside diphosphate kinase A5J299 A5J299_PENVA Penaeus vannamei 2 0.7209
Prothrombin P00734 THRB_HUMAN Homo sapiens 2 0.7207
Prothrombin P00734 THRB_HUMAN Homo sapiens 2 0.7207
Ribosomal protein L11 methyltransferase Q84BQ9 PRMA_THET8 Thermus thermophilus 2 0.7206
Ribosomal protein L11 methyltransferase Q84BQ9 PRMA_THET8 Thermus thermophilus 2 0.7206
Neocarzinostatin P0A3R9 NCZS_STRCZ Streptomyces carzinostaticus 2 0.7205
Neocarzinostatin P0A3R9 NCZS_STRCZ Streptomyces carzinostaticus 2 0.7205
Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial Q0QF01 SDHA_PIG Sus scrofa 2 0.7204
Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial Q0QF01 SDHA_PIG Sus scrofa 2 0.7204
Carbonic anhydrase Q39588 Q39588_CHLRE Chlamydomonas reinhardtii 2 0.7203
Carbonic anhydrase Q39588 Q39588_CHLRE Chlamydomonas reinhardtii 2 0.7203
Proline iminopeptidase O32449 PIP_SERMA Serratia marcescens 2 0.7199
Proline iminopeptidase O32449 PIP_SERMA Serratia marcescens 2 0.7199
Carbonic anhydrase 1 P00915 CAH1_HUMAN Homo sapiens 2 0.7189
Putative snRNP Sm-like protein Q8ZYG5 Q8ZYG5_PYRAE Pyrobaculum aerophilum 2 0.7189
Putative snRNP Sm-like protein Q8ZYG5 Q8ZYG5_PYRAE Pyrobaculum aerophilum 2 0.7189
Carbonic anhydrase 1 P00915 CAH1_HUMAN Homo sapiens 2 0.7189
Toluene-4-monooxygenase system, hydroxylase component subunit alpha Q00456 TMOA_PSEME Pseudomonas mendocina 2 0.7188
Toluene-4-monooxygenase system, hydroxylase component subunit alpha Q00456 TMOA_PSEME Pseudomonas mendocina 2 0.7188
S-methyl-5'-thioadenosine phosphorylase I0B503 I0B503_SCHMA Schistosoma mansoni 2 0.7188
S-methyl-5'-thioadenosine phosphorylase I0B503 I0B503_SCHMA Schistosoma mansoni 2 0.7188
DNA gyrase subunit A P0AES5 GYRA_SHIFL Shigella flexneri 2 0.7186
Transcriptional activator, LuxR/UhpA family of regulators Q7NQP7 Q7NQP7_CHRVO Chromobacterium violaceum 2 0.7186
Transcriptional activator, LuxR/UhpA family of regulators Q7NQP7 Q7NQP7_CHRVO Chromobacterium violaceum 2 0.7186
DNA gyrase subunit A P0AES5 GYRA_SHIFL Shigella flexneri 2 0.7186
Snake venom metalloproteinase atrolysin-D P15167 VM1AD_CROAT Crotalus atrox 2 0.7184
Coagulation factor X P00742 FA10_HUMAN Homo sapiens 2 0.7184
Snake venom metalloproteinase atrolysin-D P15167 VM1AD_CROAT Crotalus atrox 2 0.7184
Coagulation factor X P00742 FA10_HUMAN Homo sapiens 2 0.7184
L-lactate dehydrogenase (cytochrome) P00175 CYB2_YEAST Saccharomyces cerevisiae 2 0.7177
Nitric oxide synthase, inducible P29477 NOS2_MOUSE Mus musculus 2 0.7177
L-lactate dehydrogenase (cytochrome) P00175 CYB2_YEAST Saccharomyces cerevisiae 2 0.7177
Nitric oxide synthase, inducible P29477 NOS2_MOUSE Mus musculus 2 0.7177
Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase Q9TQS6 DHDH_MACFA Macaca fascicularis 2 0.7171
Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase Q9TQS6 DHDH_MACFA Macaca fascicularis 2 0.7171
Mitogen-activated protein kinase 14 Q16539 MK14_HUMAN Homo sapiens 2 0.7169
Nitric oxide synthase, inducible P29477 NOS2_MOUSE Mus musculus 2 0.7169
Nitric oxide synthase, inducible P29477 NOS2_MOUSE Mus musculus 2 0.7169
Mitogen-activated protein kinase 14 Q16539 MK14_HUMAN Homo sapiens 2 0.7169
Methionine aminopeptidase 1 P53582 MAP11_HUMAN Homo sapiens 2 0.7168
Methionine aminopeptidase 1 P53582 MAP11_HUMAN Homo sapiens 2 0.7168
Mitogen-activated protein kinase 14 Q16539 MK14_HUMAN Homo sapiens 2 0.7166
Mitogen-activated protein kinase 14 Q16539 MK14_HUMAN Homo sapiens 2 0.7166
Beta-galactoside-specific lectin 1 P81446 ML1_VISAL Viscum album 2 0.7166
Beta-galactoside-specific lectin 1 P81446 ML1_VISAL Viscum album 2 0.7166
Adenosine kinase Q9TVW2 ADK_TOXGO Toxoplasma gondii 2 0.7164
Adenosine kinase Q9TVW2 ADK_TOXGO Toxoplasma gondii 2 0.7164
Sulfotransferase 1A1 P50225 ST1A1_HUMAN Homo sapiens 2 0.7159
Sulfotransferase 1A1 P50225 ST1A1_HUMAN Homo sapiens 2 0.7159
Three-prime repair exonuclease 1 Q91XB0 TREX1_MOUSE Mus musculus 2 0.7159
Three-prime repair exonuclease 1 Q91XB0 TREX1_MOUSE Mus musculus 2 0.7159
Cyclin-dependent kinase 2 P24941 CDK2_HUMAN Homo sapiens 2 0.7155
Cyclin-dependent kinase 2 P24941 CDK2_HUMAN Homo sapiens 2 0.7155
Nucleoside diphosphate kinase 3 Q13232 NDK3_HUMAN Homo sapiens 3 0.7152
Nucleoside diphosphate kinase 3 Q13232 NDK3_HUMAN Homo sapiens 3 0.7152
Nitric oxide synthase, inducible P29477 NOS2_MOUSE Mus musculus 2 0.7150
Nitric oxide synthase, inducible P29477 NOS2_MOUSE Mus musculus 2 0.7150
Aldo-keto reductase family 1 member B1 P15121 ALDR_HUMAN Homo sapiens 2 0.7149
Aldo-keto reductase family 1 member B1 P15121 ALDR_HUMAN Homo sapiens 2 0.7149
Phospholipase A2, major isoenzyme P00592 PA21B_PIG Sus scrofa 2 0.7147
Phospholipase A2, major isoenzyme P00592 PA21B_PIG Sus scrofa 2 0.7147
Bis(5'-adenosyl)-triphosphatase P49789 FHIT_HUMAN Homo sapiens 2 0.7145
Bis(5'-adenosyl)-triphosphatase P49789 FHIT_HUMAN Homo sapiens 2 0.7145
Metallo-beta-lactamase type 2 C7C422 BLAN1_KLEPN Klebsiella pneumoniae 3 0.7144
Metallo-beta-lactamase type 2 C7C422 BLAN1_KLEPN Klebsiella pneumoniae 3 0.7144
Serine/threonine-protein kinase Chk2 O96017 CHK2_HUMAN Homo sapiens 2 0.7143
Serine/threonine-protein kinase Chk2 O96017 CHK2_HUMAN Homo sapiens 2 0.7143
7,8-dihydroneopterin aldolase J7VEZ6 J7VEZ6_BACCE Bacillus cereus BAG3X2-1 2 0.7142
7,8-dihydroneopterin aldolase J7VEZ6 J7VEZ6_BACCE Bacillus cereus BAG3X2-1 2 0.7142
Urokinase-type plasminogen activator P00749 UROK_HUMAN Homo sapiens 2 0.7141
Urokinase-type plasminogen activator P00749 UROK_HUMAN Homo sapiens 2 0.7141
Streptavidin P22629 SAV_STRAV Streptomyces avidinii 2 0.7137
Streptavidin P22629 SAV_STRAV Streptomyces avidinii 2 0.7137
Acetolactate synthase, catabolic P27696 ILVB_KLEPN Klebsiella pneumoniae 2 0.7136
Acetolactate synthase, catabolic P27696 ILVB_KLEPN Klebsiella pneumoniae 2 0.7136
Heat shock cognate 71 kDa protein P11142 HSP7C_HUMAN Homo sapiens 2 0.7135
Heat shock cognate 71 kDa protein P11142 HSP7C_HUMAN Homo sapiens 2 0.7135
Trichothecene 15-O-acetyltransferase TRI3 Q9C1B7 TRI3_FUSSP Fusarium sporotrichioides 2 0.7134
Trichothecene 15-O-acetyltransferase TRI3 Q9C1B7 TRI3_FUSSP Fusarium sporotrichioides 2 0.7134
Amine oxidase [flavin-containing] B P27338 AOFB_HUMAN Homo sapiens 2 0.7131
Amine oxidase [flavin-containing] B P27338 AOFB_HUMAN Homo sapiens 2 0.7131
Avidin P02701 AVID_CHICK Gallus gallus 2 0.7129
Avidin P02701 AVID_CHICK Gallus gallus 2 0.7129
nebramycin 5' synthase Q70IY1 TOBZ_STRSD Streptoalloteichus tenebrarius 2 0.7123
nebramycin 5' synthase Q70IY1 TOBZ_STRSD Streptoalloteichus tenebrarius 2 0.7123
SKP1-like protein 1A Q39255 SKP1A_ARATH Arabidopsis thaliana 2 0.7116
Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 2 O95340 PAPS2_HUMAN Homo sapiens 2 0.7116
SKP1-like protein 1A Q39255 SKP1A_ARATH Arabidopsis thaliana 2 0.7116
Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 2 O95340 PAPS2_HUMAN Homo sapiens 2 0.7116
Polyamine oxidase FMS1 P50264 FMS1_YEAST Saccharomyces cerevisiae 2 0.7112
Prothrombin P00734 THRB_HUMAN Homo sapiens 3 0.7112
Polyamine oxidase FMS1 P50264 FMS1_YEAST Saccharomyces cerevisiae 2 0.7112
Prothrombin P00734 THRB_HUMAN Homo sapiens 3 0.7112
Nitric oxide synthase, inducible P29477 NOS2_MOUSE Mus musculus 2 0.7111
Purine nucleoside phosphorylase DeoD-type P0ABP9 DEOD_ECO57 Escherichia coli O157:H7 2 0.7111
Nitric oxide synthase, inducible P29477 NOS2_MOUSE Mus musculus 2 0.7111
Purine nucleoside phosphorylase DeoD-type P0ABP9 DEOD_ECO57 Escherichia coli O157:H7 2 0.7111
Coniferyl alcohol 9-O-methyltransferase A6XNE6 A6XNE6_9ROSI Linum nodiflorum 2 0.7110
Coniferyl alcohol 9-O-methyltransferase A6XNE6 A6XNE6_9ROSI Linum nodiflorum 2 0.7110
Proline iminopeptidase O32449 PIP_SERMA Serratia marcescens 2 0.7106
Proline iminopeptidase O32449 PIP_SERMA Serratia marcescens 2 0.7106
Uncharacterized ACR, COG1565 superfamily Q2T1U7 Q2T1U7_BURTA Burkholderia thailandensis 2 0.7104
Uncharacterized ACR, COG1565 superfamily Q2T1U7 Q2T1U7_BURTA Burkholderia thailandensis 2 0.7104
Polymerase basic protein 2 P31345 PB2_I75A3 Influenza A virus 2 0.7098
Polymerase basic protein 2 P31345 PB2_I75A3 Influenza A virus 2 0.7098
Proline iminopeptidase O32449 PIP_SERMA Serratia marcescens 2 0.7097
Proline iminopeptidase O32449 PIP_SERMA Serratia marcescens 2 0.7097
Purine nucleoside phosphorylase DeoD-type Q5EEL8 DEOD_BACCE Bacillus cereus 2 0.7096
Branched-chain-amino-acid aminotransferase, mitochondrial O15382 BCAT2_HUMAN Homo sapiens 2 0.7096
Purine nucleoside phosphorylase DeoD-type Q5EEL8 DEOD_BACCE Bacillus cereus 2 0.7096
Branched-chain-amino-acid aminotransferase, mitochondrial O15382 BCAT2_HUMAN Homo sapiens 2 0.7096
Prothrombin P00734 THRB_HUMAN Homo sapiens 3 0.7094
Prothrombin P00734 THRB_HUMAN Homo sapiens 3 0.7094
adenine phosphoribosyltransferase Q967M2 Q967M2_GIAIN Giardia intestinalis 2 0.7093
Purine nucleoside phosphorylase, putative A2E7Y6 A2E7Y6_TRIVA Trichomonas vaginalis 2 0.7093
Purine nucleoside phosphorylase, putative A2E7Y6 A2E7Y6_TRIVA Trichomonas vaginalis 2 0.7093
adenine phosphoribosyltransferase Q967M2 Q967M2_GIAIN Giardia intestinalis 2 0.7093
4-diphosphocytidyl-2-C-methyl-D-erythritol kinase O67060 ISPE_AQUAE Aquifex aeolicus 2 0.7090
4-diphosphocytidyl-2-C-methyl-D-erythritol kinase O67060 ISPE_AQUAE Aquifex aeolicus 2 0.7090
Cobalt-precorrin-4 C(11)-methyltransferase O87696 CBIF_BACME Priestia megaterium 2 0.7087
Cobalt-precorrin-4 C(11)-methyltransferase O87696 CBIF_BACME Priestia megaterium 2 0.7087
D-aminoacyl-tRNA deacylase Q8IIS0 DTD_PLAF7 Plasmodium falciparum 2 0.7074
D-aminoacyl-tRNA deacylase Q8IIS0 DTD_PLAF7 Plasmodium falciparum 2 0.7074
Rhodopsin kinase GRK1 P28327 GRK1_BOVIN Bos taurus 2 0.7073
Rhodopsin kinase GRK1 P28327 GRK1_BOVIN Bos taurus 2 0.7073
Sex hormone-binding globulin P04278 SHBG_HUMAN Homo sapiens 2 0.7071
Sex hormone-binding globulin P04278 SHBG_HUMAN Homo sapiens 2 0.7071
Nitric oxide synthase, inducible P29477 NOS2_MOUSE Mus musculus 2 0.7065
Nitric oxide synthase, inducible P29477 NOS2_MOUSE Mus musculus 2 0.7065
Mandelate racemase P11444 MANR_PSEPU Pseudomonas putida 2 0.7064
Mandelate racemase P11444 MANR_PSEPU Pseudomonas putida 2 0.7064
ActVA 6 protein Q53908 Q53908_STRCH Streptomyces coelicolor 2 0.7062
ActVA 6 protein Q53908 Q53908_STRCH Streptomyces coelicolor 2 0.7062
Nucleoside 2-deoxyribosyltransferase Q8RLY5 Q8RLY5_LACHE Lactobacillus helveticus 2 0.7060
Protein mono-ADP-ribosyltransferase PARP14 Q460N5 PAR14_HUMAN Homo sapiens 2 0.7060
Nucleoside 2-deoxyribosyltransferase Q8RLY5 Q8RLY5_LACHE Lactobacillus helveticus 2 0.7060
Protein mono-ADP-ribosyltransferase PARP14 Q460N5 PAR14_HUMAN Homo sapiens 2 0.7060
Formate--tetrahydrofolate ligase P21164 FTHS_MOOTH Moorella thermoacetica 2 0.7059
Formate--tetrahydrofolate ligase P21164 FTHS_MOOTH Moorella thermoacetica 2 0.7059
Carbonic anhydrase 2 P00918 CAH2_HUMAN Homo sapiens 2 0.7056
Carbonic anhydrase 2 P00918 CAH2_HUMAN Homo sapiens 2 0.7056
Endothiapepsin P11838 CARP_CRYPA Cryphonectria parasitica 2 0.7055
Endothiapepsin P11838 CARP_CRYPA Cryphonectria parasitica 2 0.7055
BH2602 protein Q9K9P3 Q9K9P3_BACHD Bacillus halodurans 2 0.7052
Lactoperoxidase A0A452E9Y6 PERL_CAPHI Capra hircus 2 0.7052
BH2602 protein Q9K9P3 Q9K9P3_BACHD Bacillus halodurans 2 0.7052
Lactoperoxidase A0A452E9Y6 PERL_CAPHI Capra hircus 2 0.7052
Acidic mammalian chitinase Q9BZP6 CHIA_HUMAN Homo sapiens 2 0.7050
Acidic mammalian chitinase Q9BZP6 CHIA_HUMAN Homo sapiens 2 0.7050
Acidic phospholipase A2 3 P60045 PA2A3_NAJSG Naja sagittifera 2 0.7049
Acidic phospholipase A2 3 P60045 PA2A3_NAJSG Naja sagittifera 2 0.7049
Nitric oxide synthase, inducible P35228 NOS2_HUMAN Homo sapiens 2 0.7043
Nitric oxide synthase, inducible P35228 NOS2_HUMAN Homo sapiens 2 0.7043
Purine nucleoside phosphorylase DeoD-type B1JL34 DEOD_YERPY Yersinia pseudotuberculosis serotype O:3 2 0.7040
Purine nucleoside phosphorylase DeoD-type B1JL34 DEOD_YERPY Yersinia pseudotuberculosis serotype O:3 2 0.7040
Nucleoside diphosphate kinase Q2SWE7 NDK_BURTA Burkholderia thailandensis 2 0.7038
Nucleoside diphosphate kinase Q2SWE7 NDK_BURTA Burkholderia thailandensis 2 0.7038
ATP-dependent 6-phosphofructokinase isozyme 2 P06999 PFKB_ECOLI Escherichia coli 2 0.7038
ATP-dependent 6-phosphofructokinase isozyme 2 P06999 PFKB_ECOLI Escherichia coli 2 0.7038
Heat shock protein HSP 90-alpha P07900 HS90A_HUMAN Homo sapiens 2 0.7036
Heat shock protein HSP 90-alpha P07900 HS90A_HUMAN Homo sapiens 2 0.7036
Purine nucleoside phosphorylase DeoD-type P0ABP9 DEOD_ECO57 Escherichia coli O157:H7 2 0.7035
Purine nucleoside phosphorylase DeoD-type P0ABP9 DEOD_ECO57 Escherichia coli O157:H7 2 0.7035
Glutaminyl-peptide cyclotransferase Q16769 QPCT_HUMAN Homo sapiens 3 0.7034
Glutaminyl-peptide cyclotransferase Q16769 QPCT_HUMAN Homo sapiens 3 0.7034
Kynurenine--oxoglutarate transaminase 1 Q16773 KAT1_HUMAN Homo sapiens 2 0.7025
Kynurenine--oxoglutarate transaminase 1 Q16773 KAT1_HUMAN Homo sapiens 2 0.7025
Arginine kinase O15992 KARG_ANTJA Anthopleura japonica 2 0.7024
Arginine kinase O15992 KARG_ANTJA Anthopleura japonica 2 0.7024
SKP1-like protein 1A Q39255 SKP1A_ARATH Arabidopsis thaliana 2 0.7023
Tyrosine-protein kinase JAK3 P52333 JAK3_HUMAN Homo sapiens 2 0.7023
SKP1-like protein 1A Q39255 SKP1A_ARATH Arabidopsis thaliana 2 0.7023
Tyrosine-protein kinase JAK3 P52333 JAK3_HUMAN Homo sapiens 2 0.7023
Tryptophan synthase alpha chain P00929 TRPA_SALTY Salmonella typhimurium 2 0.7021
Tryptophan synthase alpha chain P00929 TRPA_SALTY Salmonella typhimurium 2 0.7021
APH(2'')-Id O68183 O68183_ENTCA Enterococcus casseliflavus 3 0.7014
APH(2'')-Id O68183 O68183_ENTCA Enterococcus casseliflavus 3 0.7014
2,7-dihydroxy-5-methyl-1-naphthoate 7-O-methyltransferase Q84HC8 NCSB1_STRCZ Streptomyces carzinostaticus 2 0.7012
2,7-dihydroxy-5-methyl-1-naphthoate 7-O-methyltransferase Q84HC8 NCSB1_STRCZ Streptomyces carzinostaticus 2 0.7012
4-substituted benzoates-glutamate ligase GH3.12 Q9LYU4 GH312_ARATH Arabidopsis thaliana 2 0.7010
Prothrombin P00734 THRB_HUMAN Homo sapiens 2 0.7010
4-substituted benzoates-glutamate ligase GH3.12 Q9LYU4 GH312_ARATH Arabidopsis thaliana 2 0.7010
Prothrombin P00734 THRB_HUMAN Homo sapiens 2 0.7010
Anhydro-N-acetylmuramic acid kinase Q9I5Q5 ANMK_PSEAE Pseudomonas aeruginosa 2 0.7005
Anhydro-N-acetylmuramic acid kinase Q9I5Q5 ANMK_PSEAE Pseudomonas aeruginosa 2 0.7005
Cyclin-dependent kinase 2 P24941 CDK2_HUMAN Homo sapiens 2 0.7004
Cyclin-dependent kinase 2 P24941 CDK2_HUMAN Homo sapiens 2 0.7004

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