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Trans-N-feruloyltyramine

Family: Plantae - Solanaceae
Kingdom: Plantae
Class: Phenolic
- Subclass: Cinnamide

Canonical Smiles	COc1cc(/C=C/C(=O)NCCc2ccc(cc2)O)ccc1O
InChI	InChI=1S/C18H19NO4/c1-23-17-12-14(4-8-16(17)21)5-9-18(22)19-11-10-13-2-6-15(20)7-3-13/h2-9,12,20-21H,10-11H2,1H3,(H,19,22)/b9-5+
InChIKey	NPNNKDMSXVRADT-WEVVVXLNSA-N
Formula	C₁₈H₁₉NO₄
HBA	4
HBD	3
MW	313.35
Rotatable Bonds	6
TPSA	78.79
LogP	2.48
Number Rings	2
Number Aromatic Rings	2
Heavy Atom Count	23
Formal Charge	0
Fraction CSP3	0.17
Exact Mass	313.13
Number of Lipinski Rule Violations	0

#	Species	Family	Kingdom	NCBI Taxonomy ID
1	Salsola tetrandra	Chenopodiaceae	Plantae	264975
2	Limoniastrum guyonianum	Plumbaginaceae	Plantae	114145
3	Balanites aegyptiaca	Zygophyllaceae	Plantae	886265
4	Atriplex semibaccata	Chenopodiaceae	Plantae	417609
5	Lycium schweinfurthii	Solanaceae	Plantae	416539

Showing of synonyms

Sarker SD, Bartholomew B, et al. (2000). Alkaloids from Balanites aegyptiaca. Fitoterapia,2000,71(3),328-330. [View] [PubMed]
Elbermawi A, Halim A.F, et al. (2022). Lycium schweinfurthii: new secondary metabolites and their cytotoxic activities. Natural product research,2022, 36(20), 5134-5141. [View] [PubMed]
Elshamy A, Mohamed T, et al. (2019). New phenolics, cytotoxicity and chemosystematic significance of Atriplex semibaccata. Phytochemistry Letters, 2019, 34, 74-78. [View]
Oueslati MH, Jannet HB, et al. (2006). Phytochemical constituents from Salsola tetrandra. Journal of Natural Products,2006,69(9),1366-1369. [View] [PubMed]
Trabelsi N, Oueslati S, et al. (2014). The antioxidant properties of new dimer and two monomers of phenolic acid amides isolated from Limoniastrum guyonianum. Food Chemistry,2014,146,466-471. [View] [PubMed]

Pubchem: 5280537

Cas: 66648-43-9

Gnps: CCMSLIB00006574359

Zinc: ZINC000000901461

Kegg Ligand: C02717

Chebi: 17818

Nmrshiftdb2: 60021971

Metabolights: MTBLC17818

Chembl: CHEMBL206555

CPRiL: 293639

SMILES: c1ccccc1C=CC(=O)NCCc2ccccc2

Level: 1

Mol. Weight: 313.35 g/mol

SMILES: c1ccccc1

Level: 0

Mol. Weight: 313.35 g/mol

Antioxidant

Absorption

Caco-2 (logPapp): -4.72
Human Oral Bioavailability 20%: Bioavailable
Human Intestinal Absorption: Absorbed
Madin-Darby Canine Kidney: -4.660
Human Oral Bioavailability 50%: Bioavailable
P-Glycoprotein Inhibitor: Non-Inhibitor
P-Glycoprotein Substrate: Non-Substrate
Skin Permeability: -2.11

Distribution

Blood-Brain Barrier (CNS): -
Blood-Brain Barrier: Non-Penetrable
Fraction Unbound (Human): 0.800
Plasma Protein Binding: 54.06
Steady State Volume of Distribution: -

Metabolism

Breast Cancer Resistance Protein: Non-Inhibitor
CYP 1A2 Inhibitor: Inhibitor
CYP 1A2 Substrate: Non-Substrate
CYP 2C19 Inhibitor: Non-Inhibitor
CYP 2C19 Substrate: Non-Substrate
CYP 2C9 Inhibitor: Non-Inhibitor
CYP 2C9 Substrate: Substrate
CYP 2D6 Inhibitor: Inhibitor
CYP 2D6 Substrate: Substrate
CYP 3A4 Inhibitor: Inhibitor
CYP 3A4 Substrate: Non-Substrate
OATP1B1: Non-Inhibitor
OATP1B3: Non-Inhibitor

Excretion

Clearance: 6.250
Organic Cation Transporter 2: Non-Inhibitor
Half-Life of Drug: -

Toxicity

AMES Mutagenesis: Safe
Avian: Safe
Bee: Safe
Bioconcentration Factor: 1.040
Biodegradation: Safe
Carcinogenesis: Safe
Crustacean: Toxic
Liver Injury I (DILI): Toxic
Eye Corrosion: Safe
Eye Irritation: Safe
Maximum Tolerated Dose: 1.060
Liver Injury II: Toxic
hERG Blockers: Toxic
Daphnia Maga: 5.450
Micronucleos: Toxic
NR-AhR: Toxic
NR-AR: Safe
NR-AR-LBD: Safe
NR-Aromatase: Safe
NR-ER: Toxic
NR-ER-LBD: Safe
NR-GR: Safe
NR-PPAR-gamma: Safe
NR-TR: Safe
T. Pyriformis: 3.450
Rat (Acute): 1.760
Rat (Chronic Oral): 2.510
Fathead Minnow: 4.430
Respiratory Disease: Safe
Skin Sensitisation: Toxic
SR-ARE: Toxic
SR-ATAD5: Toxic
SR-HSE: Safe
SR-MMP: Safe
SR-p53: Toxic

General Properties

Boiling Point: 426.930
Hydration Free Energy: -12.420
Log(D) at pH=7.4: 2.670
Log(P): 2.11
Log S: -3.83
Log(Vapor Pressure): -8.07
Melting Point: 173.24
pKa Acid: 9.19
pKa Basic: 5.94

Protein Name	UniProt ID	Entry Name	Species	#Pharmacophore Points	Probability (0.7 ≤ Tversky Score ≤ 1.0)
Glycogen synthase kinase-3 beta	P49841	GSK3B_HUMAN	Homo sapiens	3	0.9635
Glycogen synthase kinase-3 beta	P49841	GSK3B_HUMAN	Homo sapiens	3	0.9635
Heat shock protein HSP 90-alpha	P07900	HS90A_HUMAN	Homo sapiens	3	0.9595
Heat shock protein HSP 90-alpha	P07900	HS90A_HUMAN	Homo sapiens	3	0.9595
ADP compounds hydrolase NudE	P45799	NUDE_ECOLI	Escherichia coli	3	0.9591
ADP compounds hydrolase NudE	P45799	NUDE_ECOLI	Escherichia coli	3	0.9591
DNA gyrase subunit A	P0AES5	GYRA_SHIFL	Shigella flexneri	3	0.9571
DNA gyrase subunit A	P0AES5	GYRA_SHIFL	Shigella flexneri	3	0.9571
Serine/threonine-protein kinase SKY1	Q03656	SKY1_YEAST	Saccharomyces cerevisiae	3	0.9534
Serine/threonine-protein kinase SKY1	Q03656	SKY1_YEAST	Saccharomyces cerevisiae	3	0.9534
HTH-type transcriptional repressor PurR	P0ACP7	PURR_ECOLI	Escherichia coli	3	0.9519
HTH-type transcriptional repressor PurR	P0ACP7	PURR_ECOLI	Escherichia coli	3	0.9519
rRNA N-glycosylase	D9J2T9	D9J2T9_MOMBA	Momordica balsamina	3	0.9470
rRNA N-glycosylase	D9J2T9	D9J2T9_MOMBA	Momordica balsamina	3	0.9470
Norsolorinic acid synthase	Q12053	AFLC_ASPPU	Aspergillus parasiticus	3	0.9468
Norsolorinic acid synthase	Q12053	AFLC_ASPPU	Aspergillus parasiticus	3	0.9468
5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase	P0AF12	MTNN_ECOLI	Escherichia coli	3	0.9384
5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase	P0AF12	MTNN_ECOLI	Escherichia coli	3	0.9384
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A	Q9Y233	PDE10_HUMAN	Homo sapiens	3	0.9340
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A	Q9Y233	PDE10_HUMAN	Homo sapiens	3	0.9340
MAP kinase-activated protein kinase 2	P49137	MAPK2_HUMAN	Homo sapiens	3	0.9333
MAP kinase-activated protein kinase 2	P49137	MAPK2_HUMAN	Homo sapiens	3	0.9333
S-adenosylmethionine decarboxylase proenzyme	P17707	DCAM_HUMAN	Homo sapiens	3	0.9325
S-adenosylmethionine decarboxylase proenzyme	P17707	DCAM_HUMAN	Homo sapiens	3	0.9325
Cyclin-dependent kinase 2	P24941	CDK2_HUMAN	Homo sapiens	3	0.9286
Cyclin-dependent kinase 2	P24941	CDK2_HUMAN	Homo sapiens	3	0.9286
Ribosyldihydronicotinamide dehydrogenase [quinone]	P16083	NQO2_HUMAN	Homo sapiens	3	0.9254
Ribosyldihydronicotinamide dehydrogenase [quinone]	P16083	NQO2_HUMAN	Homo sapiens	3	0.9254
Glutamate receptor 2	P19491	GRIA2_RAT	Rattus norvegicus	3	0.9206
Glutamate receptor 2	P19491	GRIA2_RAT	Rattus norvegicus	3	0.9206
ATP-dependent molecular chaperone HSP82	P02829	HSP82_YEAST	Saccharomyces cerevisiae	3	0.9203
ATP-dependent molecular chaperone HSP82	P02829	HSP82_YEAST	Saccharomyces cerevisiae	3	0.9203
Coniferyl alcohol 9-O-methyltransferase	A6XNE6	A6XNE6_9ROSI	Linum nodiflorum	3	0.9197
Coniferyl alcohol 9-O-methyltransferase	A6XNE6	A6XNE6_9ROSI	Linum nodiflorum	3	0.9197
Urokinase-type plasminogen activator	P00749	UROK_HUMAN	Homo sapiens	3	0.9190
Urokinase-type plasminogen activator	P00749	UROK_HUMAN	Homo sapiens	3	0.9190
Protein kinase C iota type	Q62074	KPCI_MOUSE	Mus musculus	3	0.9180
Protein kinase C iota type	Q62074	KPCI_MOUSE	Mus musculus	3	0.9180
Chitinase A	Q9AMP1	Q9AMP1_VIBHA	Vibrio harveyi	3	0.9179
Chitinase A	Q9AMP1	Q9AMP1_VIBHA	Vibrio harveyi	3	0.9179
Casein kinase II subunit alpha	P68400	CSK21_HUMAN	Homo sapiens	3	0.9154
Casein kinase II subunit alpha	P68400	CSK21_HUMAN	Homo sapiens	3	0.9154
3'-5' exoribonuclease Rv2179c	P9WJ73	EXRBN_MYCTU	Mycobacterium tuberculosis	3	0.9134
3'-5' exoribonuclease Rv2179c	P9WJ73	EXRBN_MYCTU	Mycobacterium tuberculosis	3	0.9134
Glutamate receptor 2	P19491	GRIA2_RAT	Rattus norvegicus	3	0.9128
Glutamate receptor 2	P19491	GRIA2_RAT	Rattus norvegicus	3	0.9128
Myosin heavy chain kinase A	P42527	MHCKA_DICDI	Dictyostelium discoideum	3	0.9094
Myosin heavy chain kinase A	P42527	MHCKA_DICDI	Dictyostelium discoideum	3	0.9094
Glutamate receptor 2	P19491	GRIA2_RAT	Rattus norvegicus	3	0.9092
Glutamate receptor 2	P19491	GRIA2_RAT	Rattus norvegicus	3	0.9092
Secoisolariciresinol dehydrogenase	Q94KL8	SILD_PODPE	Podophyllum peltatum	4	0.9073
Secoisolariciresinol dehydrogenase	Q94KL8	SILD_PODPE	Podophyllum peltatum	4	0.9073
Serine/threonine-protein kinase toxin HipA	P23874	HIPA_ECOLI	Escherichia coli	3	0.9045
Serine/threonine-protein kinase toxin HipA	P23874	HIPA_ECOLI	Escherichia coli	3	0.9045
Glutathione S-transferase F2	P46422	GSTF2_ARATH	Arabidopsis thaliana	3	0.9031
Glutathione S-transferase F2	P46422	GSTF2_ARATH	Arabidopsis thaliana	3	0.9031
Matrilysin	P09237	MMP7_HUMAN	Homo sapiens	4	0.8998
Matrilysin	P09237	MMP7_HUMAN	Homo sapiens	4	0.8998
HTH-type transcriptional repressor PurR	P0ACP7	PURR_ECOLI	Escherichia coli	3	0.8996
HTH-type transcriptional repressor PurR	P0ACP7	PURR_ECOLI	Escherichia coli	3	0.8996
LIM domain kinase 1	P53667	LIMK1_HUMAN	Homo sapiens	3	0.8990
LIM domain kinase 1	P53667	LIMK1_HUMAN	Homo sapiens	3	0.8990
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	P48736	PK3CG_HUMAN	Homo sapiens	3	0.8989
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	P48736	PK3CG_HUMAN	Homo sapiens	3	0.8989
HTH-type transcriptional repressor PurR	P0ACP7	PURR_ECOLI	Escherichia coli	3	0.8973
HTH-type transcriptional repressor PurR	P0ACP7	PURR_ECOLI	Escherichia coli	3	0.8973
Rhodopsin kinase GRK1	P28327	GRK1_BOVIN	Bos taurus	3	0.8963
Rhodopsin kinase GRK1	P28327	GRK1_BOVIN	Bos taurus	3	0.8963
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A	Q9QYJ6	PDE10_RAT	Rattus norvegicus	3	0.8930
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A	Q9QYJ6	PDE10_RAT	Rattus norvegicus	3	0.8930
Capsid protein	Q9WBP8	Q9WBP8_9VIRU	Adeno-associated virus - 1	3	0.8921
Capsid protein	Q9WBP8	Q9WBP8_9VIRU	Adeno-associated virus - 1	3	0.8921
Cyclin-dependent kinase 2	P24941	CDK2_HUMAN	Homo sapiens	3	0.8885
Valacyclovir hydrolase	Q86WA6	BPHL_HUMAN	Homo sapiens	3	0.8885
Valacyclovir hydrolase	Q86WA6	BPHL_HUMAN	Homo sapiens	3	0.8885
Cyclin-dependent kinase 2	P24941	CDK2_HUMAN	Homo sapiens	3	0.8885
Gag-Pol polyprotein	P03367	POL_HV1BR	Human immunodeficiency virus type 1 group M subtype B	3	0.8876
Gag-Pol polyprotein	P03367	POL_HV1BR	Human immunodeficiency virus type 1 group M subtype B	3	0.8876
Cyclin-dependent kinase 2	P24941	CDK2_HUMAN	Homo sapiens	3	0.8865
Cyclin-dependent kinase 2	P24941	CDK2_HUMAN	Homo sapiens	3	0.8865
Thymidine phosphorylase	Q7CP66	TYPH_SALTY	Salmonella typhimurium	3	0.8856
Thymidine phosphorylase	Q7CP66	TYPH_SALTY	Salmonella typhimurium	3	0.8856
Tyrosine-protein kinase JAK2	O60674	JAK2_HUMAN	Homo sapiens	3	0.8852
Tyrosine-protein kinase JAK2	O60674	JAK2_HUMAN	Homo sapiens	3	0.8852
Tyrosine-protein kinase JAK2	O60674	JAK2_HUMAN	Homo sapiens	4	0.8834
Tyrosine-protein kinase JAK2	O60674	JAK2_HUMAN	Homo sapiens	4	0.8834
D-aminoacyl-tRNA deacylase	Q8IIS0	DTD_PLAF7	Plasmodium falciparum	3	0.8823
D-aminoacyl-tRNA deacylase	Q8IIS0	DTD_PLAF7	Plasmodium falciparum	3	0.8823
Uracil phosphoribosyltransferase	Q26998	UPP_TOXGO	Toxoplasma gondii	3	0.8816
Uracil phosphoribosyltransferase	Q26998	UPP_TOXGO	Toxoplasma gondii	3	0.8816
Tyrosine-protein kinase JAK1	P23458	JAK1_HUMAN	Homo sapiens	4	0.8791
Tyrosine-protein kinase JAK1	P23458	JAK1_HUMAN	Homo sapiens	4	0.8791
Thermolysin	P00800	THER_BACTH	Bacillus thermoproteolyticus	3	0.8788
Thermolysin	P00800	THER_BACTH	Bacillus thermoproteolyticus	3	0.8788
NADPH dehydrogenase 1	Q02899	OYE1_SACPS	Saccharomyces pastorianus	3	0.8786
NADPH dehydrogenase 1	Q02899	OYE1_SACPS	Saccharomyces pastorianus	3	0.8786
Genome polyprotein	P26663	POLG_HCVBK	Hepatitis C virus genotype 1b	3	0.8779
Genome polyprotein	P26663	POLG_HCVBK	Hepatitis C virus genotype 1b	3	0.8779
Mycocyclosin synthase	P9WPP7	CP121_MYCTU	Mycobacterium tuberculosis	3	0.8763
Mycocyclosin synthase	P9WPP7	CP121_MYCTU	Mycobacterium tuberculosis	3	0.8763
Heat shock protein HSP 90-alpha	P07900	HS90A_HUMAN	Homo sapiens	3	0.8759
Heat shock protein HSP 90-alpha	P07900	HS90A_HUMAN	Homo sapiens	3	0.8759
Glutamate receptor 2	P19491	GRIA2_RAT	Rattus norvegicus	3	0.8740
Glutamate receptor 2	P19491	GRIA2_RAT	Rattus norvegicus	3	0.8740
Tetracycline repressor protein class B from transposon Tn10	P04483	TETR2_ECOLX	Escherichia coli	3	0.8739
Tetracycline repressor protein class B from transposon Tn10	P04483	TETR2_ECOLX	Escherichia coli	3	0.8739
Glycogen synthase kinase-3 beta	P49841	GSK3B_HUMAN	Homo sapiens	3	0.8733
Glycogen synthase kinase-3 beta	P49841	GSK3B_HUMAN	Homo sapiens	3	0.8733
Laminarinase	Q9WXN1	Q9WXN1_THEMA	Thermotoga maritima	3	0.8727
Laminarinase	Q9WXN1	Q9WXN1_THEMA	Thermotoga maritima	3	0.8727
Carbonic anhydrase 2	P00918	CAH2_HUMAN	Homo sapiens	3	0.8726
Carbonic anhydrase 2	P00918	CAH2_HUMAN	Homo sapiens	3	0.8726
Heat shock protein HSP 90-alpha	P07900	HS90A_HUMAN	Homo sapiens	3	0.8721
Heat shock protein HSP 90-alpha	P07900	HS90A_HUMAN	Homo sapiens	3	0.8721
Uracil phosphoribosyltransferase	Q26998	UPP_TOXGO	Toxoplasma gondii	3	0.8692
Uracil phosphoribosyltransferase	Q26998	UPP_TOXGO	Toxoplasma gondii	3	0.8692
Methionine aminopeptidase 2	P50579	MAP2_HUMAN	Homo sapiens	3	0.8674
Methionine aminopeptidase 2	P50579	MAP2_HUMAN	Homo sapiens	3	0.8674
Kinesin-like protein KIF11	P52732	KIF11_HUMAN	Homo sapiens	3	0.8662
Kinesin-like protein KIF11	P52732	KIF11_HUMAN	Homo sapiens	3	0.8662
Macrophage metalloelastase	P39900	MMP12_HUMAN	Homo sapiens	3	0.8658
Macrophage metalloelastase	P39900	MMP12_HUMAN	Homo sapiens	3	0.8658
Cathepsin S	P25774	CATS_HUMAN	Homo sapiens	3	0.8656
Cathepsin S	P25774	CATS_HUMAN	Homo sapiens	3	0.8656
Serine/threonine-protein kinase Chk1	O14757	CHK1_HUMAN	Homo sapiens	3	0.8653
Serine/threonine-protein kinase Chk1	O14757	CHK1_HUMAN	Homo sapiens	3	0.8653
3',5'-cyclic-AMP phosphodiesterase 4D	Q08499	PDE4D_HUMAN	Homo sapiens	3	0.8652
3',5'-cyclic-AMP phosphodiesterase 4D	Q08499	PDE4D_HUMAN	Homo sapiens	3	0.8652
Streptogramin A acetyltransferase	P50870	VATD_ENTFC	Enterococcus faecium	3	0.8641
Streptogramin A acetyltransferase	P50870	VATD_ENTFC	Enterococcus faecium	3	0.8641
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase	Q8DNV6	Q8DNV6_STRR6	Streptococcus pneumoniae	3	0.8627
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase	Q8DNV6	Q8DNV6_STRR6	Streptococcus pneumoniae	3	0.8627
Nitric oxide synthase, inducible	P29477	NOS2_MOUSE	Mus musculus	3	0.8614
Nitric oxide synthase, inducible	P29477	NOS2_MOUSE	Mus musculus	3	0.8614
Mitogen-activated protein kinase 14	Q16539	MK14_HUMAN	Homo sapiens	3	0.8610
Mitogen-activated protein kinase 14	Q16539	MK14_HUMAN	Homo sapiens	3	0.8610
Caffeic acid O-methyltransferase	Q9ZTU2	Q9ZTU2_LOLPR	Lolium perenne	4	0.8606
Caffeic acid O-methyltransferase	Q9ZTU2	Q9ZTU2_LOLPR	Lolium perenne	4	0.8606
Beta-1 adrenergic receptor	P07700	ADRB1_MELGA	Meleagris gallopavo	3	0.8605
Beta-1 adrenergic receptor	P07700	ADRB1_MELGA	Meleagris gallopavo	3	0.8605
RIO-type serine/threonine-protein kinase Rio1	O28471	RIO1_ARCFU	Archaeoglobus fulgidus	3	0.8602
RIO-type serine/threonine-protein kinase Rio1	O28471	RIO1_ARCFU	Archaeoglobus fulgidus	3	0.8602
Dual specificity mitogen-activated protein kinase kinase 1	Q02750	MP2K1_HUMAN	Homo sapiens	3	0.8586
Dual specificity mitogen-activated protein kinase kinase 1	Q02750	MP2K1_HUMAN	Homo sapiens	3	0.8586
Biotin carboxylase	P24182	ACCC_ECOLI	Escherichia coli	3	0.8578
Biotin carboxylase	P24182	ACCC_ECOLI	Escherichia coli	3	0.8578
Gag-Pol polyprotein	P03369	POL_HV1A2	Human immunodeficiency virus type 1 group M subtype B	3	0.8570
Gag-Pol polyprotein	P03369	POL_HV1A2	Human immunodeficiency virus type 1 group M subtype B	3	0.8570
Heat shock protein HSP 90-alpha	P07900	HS90A_HUMAN	Homo sapiens	3	0.8554
Heat shock protein HSP 90-alpha	P07900	HS90A_HUMAN	Homo sapiens	3	0.8554
Nicotinamide phosphoribosyltransferase	P43490	NAMPT_HUMAN	Homo sapiens	3	0.8546
Nicotinamide phosphoribosyltransferase	P43490	NAMPT_HUMAN	Homo sapiens	3	0.8546
Lactoperoxidase	P80025	PERL_BOVIN	Bos taurus	3	0.8539
Pantothenate synthetase	P9WIL5	PANC_MYCTU	Mycobacterium tuberculosis	3	0.8539
Lactoperoxidase	P80025	PERL_BOVIN	Bos taurus	3	0.8539
Pantothenate synthetase	P9WIL5	PANC_MYCTU	Mycobacterium tuberculosis	3	0.8539
Ephrin type-B receptor 2	P54763	EPHB2_MOUSE	Mus musculus	3	0.8536
Ephrin type-B receptor 2	P54763	EPHB2_MOUSE	Mus musculus	3	0.8536
Mitogen-activated protein kinase 1	P28482	MK01_HUMAN	Homo sapiens	3	0.8530
Mitogen-activated protein kinase 1	P28482	MK01_HUMAN	Homo sapiens	3	0.8530
Ribosyldihydronicotinamide dehydrogenase [quinone]	P16083	NQO2_HUMAN	Homo sapiens	3	0.8524
Ribosyldihydronicotinamide dehydrogenase [quinone]	P16083	NQO2_HUMAN	Homo sapiens	3	0.8524
Threonine synthase 1, chloroplastic	Q9S7B5	THRC1_ARATH	Arabidopsis thaliana	3	0.8518
Threonine synthase 1, chloroplastic	Q9S7B5	THRC1_ARATH	Arabidopsis thaliana	3	0.8518
5-methylthioadenosine/S-adenosylhomocysteine deaminase	Q7NZ90	Q7NZ90_CHRVO	Chromobacterium violaceum	3	0.8514
5-methylthioadenosine/S-adenosylhomocysteine deaminase	Q7NZ90	Q7NZ90_CHRVO	Chromobacterium violaceum	3	0.8514
Hexokinase-4	P35557	HXK4_HUMAN	Homo sapiens	3	0.8511
Hexokinase-4	P35557	HXK4_HUMAN	Homo sapiens	3	0.8511
Proto-oncogene tyrosine-protein kinase Src	P00523	SRC_CHICK	Gallus gallus	4	0.8509
Proto-oncogene tyrosine-protein kinase Src	P00523	SRC_CHICK	Gallus gallus	4	0.8509
Histone deacetylase 4	P56524	HDAC4_HUMAN	Homo sapiens	3	0.8500
Histone deacetylase 4	P56524	HDAC4_HUMAN	Homo sapiens	3	0.8500
Serine/threonine-protein kinase pim-1	P11309	PIM1_HUMAN	Homo sapiens	3	0.8493
Serine/threonine-protein kinase pim-1	P11309	PIM1_HUMAN	Homo sapiens	3	0.8493
Pteridine reductase	O76290	O76290_TRYBB	Trypanosoma brucei brucei	3	0.8482
Pteridine reductase	O76290	O76290_TRYBB	Trypanosoma brucei brucei	3	0.8482
Kinesin-like protein KIF11	P52732	KIF11_HUMAN	Homo sapiens	3	0.8466
Kinesin-like protein KIF11	P52732	KIF11_HUMAN	Homo sapiens	3	0.8466
Glycogen synthase kinase-3 beta	P49841	GSK3B_HUMAN	Homo sapiens	4	0.8461
Glycogen synthase kinase-3 beta	P49841	GSK3B_HUMAN	Homo sapiens	4	0.8461
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial	Q15119	PDK2_HUMAN	Homo sapiens	3	0.8460
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial	Q15119	PDK2_HUMAN	Homo sapiens	3	0.8460
APH(2'')-Id	O68183	O68183_ENTCA	Enterococcus casseliflavus	4	0.8452
APH(2'')-Id	O68183	O68183_ENTCA	Enterococcus casseliflavus	4	0.8452
Nicotinamide phosphoribosyltransferase	P43490	NAMPT_HUMAN	Homo sapiens	3	0.8449
Nicotinamide phosphoribosyltransferase	P43490	NAMPT_HUMAN	Homo sapiens	3	0.8449
Kinesin-like protein KIF11	P52732	KIF11_HUMAN	Homo sapiens	3	0.8444
Kinesin-like protein KIF11	P52732	KIF11_HUMAN	Homo sapiens	3	0.8444
Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase	Q05603	COBT_SALTY	Salmonella typhimurium	3	0.8438
Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase	Q05603	COBT_SALTY	Salmonella typhimurium	3	0.8438
NAD-capped RNA hydrolase NudC	P32664	NUDC_ECOLI	Escherichia coli	3	0.8425
NAD-capped RNA hydrolase NudC	P32664	NUDC_ECOLI	Escherichia coli	3	0.8425
Tyrosine-protein kinase JAK2	O60674	JAK2_HUMAN	Homo sapiens	3	0.8422
Tyrosine-protein kinase JAK2	O60674	JAK2_HUMAN	Homo sapiens	3	0.8422
Peptidyl-prolyl cis-trans isomerase FKBP1A	P62942	FKB1A_HUMAN	Homo sapiens	3	0.8408
Peptidyl-prolyl cis-trans isomerase FKBP1A	P62942	FKB1A_HUMAN	Homo sapiens	3	0.8408
Neocarzinostatin	P0A3R9	NCZS_STRCZ	Streptomyces carzinostaticus	3	0.8400
Neocarzinostatin	P0A3R9	NCZS_STRCZ	Streptomyces carzinostaticus	3	0.8400
Major pollen allergen Bet v 1-A	P15494	BEV1A_BETPN	Betula pendula	3	0.8392
Major pollen allergen Bet v 1-A	P15494	BEV1A_BETPN	Betula pendula	3	0.8392
Serine/threonine-protein kinase Chk1	O14757	CHK1_HUMAN	Homo sapiens	3	0.8375
Serine/threonine-protein kinase Chk1	O14757	CHK1_HUMAN	Homo sapiens	3	0.8375
NAD-dependent protein deacetylase	Q9WYW0	NPD_THEMA	Thermotoga maritima	3	0.8371
NAD-dependent protein deacetylase	Q9WYW0	NPD_THEMA	Thermotoga maritima	3	0.8371
Heat shock protein HSP 90-alpha	P07900	HS90A_HUMAN	Homo sapiens	3	0.8355
Heat shock protein HSP 90-alpha	P07900	HS90A_HUMAN	Homo sapiens	3	0.8355
Serine/threonine-protein kinase 10	O94804	STK10_HUMAN	Homo sapiens	3	0.8351
Serine/threonine-protein kinase 10	O94804	STK10_HUMAN	Homo sapiens	3	0.8351
Serine/threonine-protein kinase 24	Q9Y6E0	STK24_HUMAN	Homo sapiens	3	0.8348
Serine/threonine-protein kinase 24	Q9Y6E0	STK24_HUMAN	Homo sapiens	3	0.8348
Queuine tRNA-ribosyltransferase	P28720	TGT_ZYMMO	Zymomonas mobilis subsp. mobilis	3	0.8320
Queuine tRNA-ribosyltransferase	P28720	TGT_ZYMMO	Zymomonas mobilis subsp. mobilis	3	0.8320
Nitric oxide synthase, inducible	P29477	NOS2_MOUSE	Mus musculus	3	0.8312
Biotin carboxylase	P43873	ACCC_HAEIN	Haemophilus influenzae	3	0.8312
Biotin carboxylase	P43873	ACCC_HAEIN	Haemophilus influenzae	3	0.8312
Nitric oxide synthase, inducible	P29477	NOS2_MOUSE	Mus musculus	3	0.8312
Proto-oncogene tyrosine-protein kinase Src	P00523	SRC_CHICK	Gallus gallus	3	0.8301
Proto-oncogene tyrosine-protein kinase Src	P00523	SRC_CHICK	Gallus gallus	3	0.8301
Carbonic anhydrase 2	P00918	CAH2_HUMAN	Homo sapiens	3	0.8292
Carbonic anhydrase 2	P00918	CAH2_HUMAN	Homo sapiens	3	0.8292
Purine nucleoside phosphorylase	P00491	PNPH_HUMAN	Homo sapiens	3	0.8275
Purine nucleoside phosphorylase	P00491	PNPH_HUMAN	Homo sapiens	3	0.8275
Purine nucleoside phosphorylase DeoD-type	O34925	DEOD_BACSU	Bacillus subtilis	3	0.8271
Purine nucleoside phosphorylase DeoD-type	O34925	DEOD_BACSU	Bacillus subtilis	3	0.8271
Tyrosine-protein kinase JAK1	P23458	JAK1_HUMAN	Homo sapiens	4	0.8270
Tyrosine-protein kinase JAK1	P23458	JAK1_HUMAN	Homo sapiens	4	0.8270
Activin receptor type-1	Q04771	ACVR1_HUMAN	Homo sapiens	3	0.8268
Activin receptor type-1	Q04771	ACVR1_HUMAN	Homo sapiens	3	0.8268
Tyrosine-protein kinase JAK3	P52333	JAK3_HUMAN	Homo sapiens	3	0.8264
Tyrosine-protein kinase JAK3	P52333	JAK3_HUMAN	Homo sapiens	3	0.8264
Purine nucleoside phosphorylase	Q9BMI9	Q9BMI9_SCHMA	Schistosoma mansoni	3	0.8262
Purine nucleoside phosphorylase	Q9BMI9	Q9BMI9_SCHMA	Schistosoma mansoni	3	0.8262
Nitric oxide synthase 1	P29476	NOS1_RAT	Rattus norvegicus	3	0.8257
Nitric oxide synthase 1	P29476	NOS1_RAT	Rattus norvegicus	3	0.8257
Nitric oxide synthase 3	P29474	NOS3_HUMAN	Homo sapiens	3	0.8242
Nitric oxide synthase 3	P29474	NOS3_HUMAN	Homo sapiens	3	0.8242
Sulfotransferase 1A1	P50225	ST1A1_HUMAN	Homo sapiens	3	0.8195
Sulfotransferase 1A1	P50225	ST1A1_HUMAN	Homo sapiens	3	0.8195
Histone deacetylase 8	Q9BY41	HDAC8_HUMAN	Homo sapiens	3	0.8186
Histone deacetylase 8	Q9BY41	HDAC8_HUMAN	Homo sapiens	3	0.8186
Histone deacetylase 8	Q9BY41	HDAC8_HUMAN	Homo sapiens	3	0.8184
Histone deacetylase 8	Q9BY41	HDAC8_HUMAN	Homo sapiens	3	0.8184
2-aminohexano-6-lactam racemase	Q7M181	ACLR_ACHOB	Achromobacter obae	3	0.8184
2-aminohexano-6-lactam racemase	Q7M181	ACLR_ACHOB	Achromobacter obae	3	0.8184
Beta-glucuronidase	P05804	BGLR_ECOLI	Escherichia coli	3	0.8168
Repressor protein	Q7X0D9	Q7X0D9_ACIAD	Acinetobacter baylyi	3	0.8168
Repressor protein	Q7X0D9	Q7X0D9_ACIAD	Acinetobacter baylyi	3	0.8168
Beta-glucuronidase	P05804	BGLR_ECOLI	Escherichia coli	3	0.8168
Ribosomal small subunit pseudouridine synthase A	P0AA43	RSUA_ECOLI	Escherichia coli	3	0.8161
Ribosomal small subunit pseudouridine synthase A	P0AA43	RSUA_ECOLI	Escherichia coli	3	0.8161
Mitogen-activated protein kinase 8	P45983	MK08_HUMAN	Homo sapiens	3	0.8137
Mitogen-activated protein kinase 8	P45983	MK08_HUMAN	Homo sapiens	3	0.8137
Nitric oxide synthase, inducible	P29477	NOS2_MOUSE	Mus musculus	3	0.8132
Nitric oxide synthase, inducible	P29477	NOS2_MOUSE	Mus musculus	3	0.8132
HTH-type transcriptional regulator TtgR	Q9AIU0	TTGR_PSEPT	Pseudomonas putida	3	0.8127
HTH-type transcriptional regulator TtgR	Q9AIU0	TTGR_PSEPT	Pseudomonas putida	3	0.8127
Mycocyclosin synthase	P9WPP7	CP121_MYCTU	Mycobacterium tuberculosis	3	0.8113
Mycocyclosin synthase	P9WPP7	CP121_MYCTU	Mycobacterium tuberculosis	3	0.8113
3',5'-cyclic-AMP phosphodiesterase 4D	Q08499	PDE4D_HUMAN	Homo sapiens	3	0.8110
3',5'-cyclic-AMP phosphodiesterase 4D	Q08499	PDE4D_HUMAN	Homo sapiens	3	0.8110
Hypoxanthine phosphoribosyltransferase	Q4DRC4	Q4DRC4_TRYCC	Trypanosoma cruzi	3	0.8103
Hypoxanthine phosphoribosyltransferase	Q4DRC4	Q4DRC4_TRYCC	Trypanosoma cruzi	3	0.8103
clade A/E 93TH057 HIV-1 gp120 core	A0A0M3KKW9	A0A0M3KKW9_9HIV1	Human immunodeficiency virus 1	3	0.8083
clade A/E 93TH057 HIV-1 gp120 core	A0A0M3KKW9	A0A0M3KKW9_9HIV1	Human immunodeficiency virus 1	3	0.8083
Tyrosine-protein kinase JAK1	P23458	JAK1_HUMAN	Homo sapiens	4	0.8067
Tyrosine-protein kinase JAK1	P23458	JAK1_HUMAN	Homo sapiens	4	0.8067
Basic phospholipase A2 VRV-PL-VIIIa	P59071	PA2B8_DABRR	Daboia russelii	3	0.8035
Basic phospholipase A2 VRV-PL-VIIIa	P59071	PA2B8_DABRR	Daboia russelii	3	0.8035
Queuine tRNA-ribosyltransferase	P28720	TGT_ZYMMO	Zymomonas mobilis subsp. mobilis	3	0.8034
Queuine tRNA-ribosyltransferase	P28720	TGT_ZYMMO	Zymomonas mobilis subsp. mobilis	3	0.8034
Thermolysin	P00800	THER_BACTH	Bacillus thermoproteolyticus	3	0.8031
Thermolysin	P00800	THER_BACTH	Bacillus thermoproteolyticus	3	0.8031
NADPH-dependent oxidoreductase 2-alkenal reductase	Q39172	AER_ARATH	Arabidopsis thaliana	3	0.8017
NADPH-dependent oxidoreductase 2-alkenal reductase	Q39172	AER_ARATH	Arabidopsis thaliana	3	0.8017
cAMP-dependent protein kinase catalytic subunit alpha	P05132	KAPCA_MOUSE	Mus musculus	3	0.7998
cAMP-dependent protein kinase catalytic subunit alpha	P05132	KAPCA_MOUSE	Mus musculus	3	0.7998
Genome polyprotein	P26663	POLG_HCVBK	Hepatitis C virus genotype 1b	4	0.7997
Genome polyprotein	P26663	POLG_HCVBK	Hepatitis C virus genotype 1b	4	0.7997
Poly [ADP-ribose] polymerase tankyrase-2	Q9H2K2	TNKS2_HUMAN	Homo sapiens	3	0.7995
Poly [ADP-ribose] polymerase tankyrase-2	Q9H2K2	TNKS2_HUMAN	Homo sapiens	3	0.7995
Steroid Delta-isomerase	P00947	SDIS_COMTE	Comamonas testosteroni	3	0.7994
Steroid Delta-isomerase	P00947	SDIS_COMTE	Comamonas testosteroni	3	0.7994
Tyrosine-protein kinase JAK1	P23458	JAK1_HUMAN	Homo sapiens	4	0.7983
Tyrosine-protein kinase JAK1	P23458	JAK1_HUMAN	Homo sapiens	4	0.7983
Mitogen-activated protein kinase 1	P28482	MK01_HUMAN	Homo sapiens	3	0.7977
Mitogen-activated protein kinase 1	P28482	MK01_HUMAN	Homo sapiens	3	0.7977
Flavonoid 3-O-glucosyltransferase	A6XNC6	UGFGT_MEDTR	Medicago truncatula	3	0.7976
Flavonoid 3-O-glucosyltransferase	A6XNC6	UGFGT_MEDTR	Medicago truncatula	3	0.7976
Bromodomain-containing protein 2	P25440	BRD2_HUMAN	Homo sapiens	3	0.7970
Bromodomain-containing protein 2	P25440	BRD2_HUMAN	Homo sapiens	3	0.7970
Toxoflavin degrading enzyme	E3SET7	E3SET7_PAEPO	Paenibacillus polymyxa	3	0.7967
Toxoflavin degrading enzyme	E3SET7	E3SET7_PAEPO	Paenibacillus polymyxa	3	0.7967
Tubulin--tyrosine ligase	F6Z895	A9ULH4_XENTR	Xenopus tropicalis	4	0.7965
Tubulin--tyrosine ligase	F6Z895	A9ULH4_XENTR	Xenopus tropicalis	4	0.7965
Tyrosine-protein kinase JAK2	O60674	JAK2_HUMAN	Homo sapiens	3	0.7954
Tyrosine-protein kinase JAK2	O60674	JAK2_HUMAN	Homo sapiens	3	0.7954
Nitric oxide synthase, inducible	P29477	NOS2_MOUSE	Mus musculus	3	0.7943
Serine/threonine-protein kinase pim-1	P11309	PIM1_HUMAN	Homo sapiens	3	0.7943
Nitric oxide synthase, inducible	P29477	NOS2_MOUSE	Mus musculus	3	0.7943
Serine/threonine-protein kinase pim-1	P11309	PIM1_HUMAN	Homo sapiens	3	0.7943
Histone deacetylase 8	Q9BY41	HDAC8_HUMAN	Homo sapiens	3	0.7934
Histone deacetylase 8	Q9BY41	HDAC8_HUMAN	Homo sapiens	3	0.7934
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial	Q15119	PDK2_HUMAN	Homo sapiens	3	0.7925
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial	Q15119	PDK2_HUMAN	Homo sapiens	3	0.7925
Poly [ADP-ribose] polymerase tankyrase-2	Q9H2K2	TNKS2_HUMAN	Homo sapiens	3	0.7924
Poly [ADP-ribose] polymerase tankyrase-2	Q9H2K2	TNKS2_HUMAN	Homo sapiens	3	0.7924
Heat shock protein HSP 90-alpha	P07900	HS90A_HUMAN	Homo sapiens	3	0.7920
Heat shock protein HSP 90-alpha	P07900	HS90A_HUMAN	Homo sapiens	3	0.7920
Bifunctional protein GlmU	P43889	GLMU_HAEIN	Haemophilus influenzae	3	0.7910
Bifunctional protein GlmU	P43889	GLMU_HAEIN	Haemophilus influenzae	3	0.7910
Gag-Pol polyprotein	P12497	POL_HV1N5	Human immunodeficiency virus type 1 group M subtype B	4	0.7893
Gag-Pol polyprotein	P12497	POL_HV1N5	Human immunodeficiency virus type 1 group M subtype B	4	0.7893
TGF-beta-activated kinase 1 and MAP3K7-binding protein 1	Q15750	TAB1_HUMAN	Homo sapiens	3	0.7891
TGF-beta-activated kinase 1 and MAP3K7-binding protein 1	Q15750	TAB1_HUMAN	Homo sapiens	3	0.7891
Cobalt-precorrin-4 C(11)-methyltransferase	O87696	CBIF_BACME	Priestia megaterium	3	0.7890
Cobalt-precorrin-4 C(11)-methyltransferase	O87696	CBIF_BACME	Priestia megaterium	3	0.7890
5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase	Q81LL4	MTNN_BACAN	Bacillus anthracis	3	0.7873
5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase	Q81LL4	MTNN_BACAN	Bacillus anthracis	3	0.7873
Mitogen-activated protein kinase 8	P45983	MK08_HUMAN	Homo sapiens	3	0.7872
Mitogen-activated protein kinase 8	P45983	MK08_HUMAN	Homo sapiens	3	0.7872
Phenylalanine-4-hydroxylase	P00439	PH4H_HUMAN	Homo sapiens	3	0.7862
Phenylalanine-4-hydroxylase	P00439	PH4H_HUMAN	Homo sapiens	3	0.7862
Pol protein	Q000H7	Q000H7_9HIV1	Human immunodeficiency virus 1	3	0.7859
Pol protein	Q000H7	Q000H7_9HIV1	Human immunodeficiency virus 1	3	0.7859
4-hydroxy-7-methoxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl glucoside beta-D-glucosidase 1, chloroplastic	P49235	HGGL1_MAIZE	Zea mays	2	0.7857
4-hydroxy-7-methoxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl glucoside beta-D-glucosidase 1, chloroplastic	P49235	HGGL1_MAIZE	Zea mays	2	0.7857
Chitinase	Q54276	Q54276_SERMA	Serratia marcescens	3	0.7853
Chitinase	Q54276	Q54276_SERMA	Serratia marcescens	3	0.7853
3-hydroxyisobutyryl-CoA hydrolase, mitochondrial	Q6NVY1	HIBCH_HUMAN	Homo sapiens	3	0.7849
3-hydroxyisobutyryl-CoA hydrolase, mitochondrial	Q6NVY1	HIBCH_HUMAN	Homo sapiens	3	0.7849
Mitogen-activated protein kinase 14	Q16539	MK14_HUMAN	Homo sapiens	3	0.7847
Mitogen-activated protein kinase 14	Q16539	MK14_HUMAN	Homo sapiens	3	0.7847
Epidermal growth factor receptor	P00533	EGFR_HUMAN	Homo sapiens	3	0.7844
Epidermal growth factor receptor	P00533	EGFR_HUMAN	Homo sapiens	3	0.7844
ALK tyrosine kinase receptor	Q9UM73	ALK_HUMAN	Homo sapiens	3	0.7844
ALK tyrosine kinase receptor	Q9UM73	ALK_HUMAN	Homo sapiens	3	0.7844
Cyclin-dependent kinase 9	P50750	CDK9_HUMAN	Homo sapiens	3	0.7841
Pteridine reductase 1	Q01782	PTR1_LEIMA	Leishmania major	3	0.7841
Cyclin-dependent kinase 9	P50750	CDK9_HUMAN	Homo sapiens	3	0.7841
Pteridine reductase 1	Q01782	PTR1_LEIMA	Leishmania major	3	0.7841
ALK tyrosine kinase receptor	Q9UM73	ALK_HUMAN	Homo sapiens	3	0.7832
ALK tyrosine kinase receptor	Q9UM73	ALK_HUMAN	Homo sapiens	3	0.7832
Dual specificity mitogen-activated protein kinase kinase 1	Q02750	MP2K1_HUMAN	Homo sapiens	3	0.7830
Dual specificity mitogen-activated protein kinase kinase 1	Q02750	MP2K1_HUMAN	Homo sapiens	3	0.7830
Glycogen phosphorylase, liver form	P06737	PYGL_HUMAN	Homo sapiens	4	0.7828
Glycogen phosphorylase, liver form	P06737	PYGL_HUMAN	Homo sapiens	4	0.7828
ALK tyrosine kinase receptor	Q9UM73	ALK_HUMAN	Homo sapiens	3	0.7818
Cyclin-dependent kinase 8	P49336	CDK8_HUMAN	Homo sapiens	3	0.7818
ALK tyrosine kinase receptor	Q9UM73	ALK_HUMAN	Homo sapiens	3	0.7818
Cyclin-dependent kinase 8	P49336	CDK8_HUMAN	Homo sapiens	3	0.7818
ALK tyrosine kinase receptor	Q9UM73	ALK_HUMAN	Homo sapiens	3	0.7818
ALK tyrosine kinase receptor	Q9UM73	ALK_HUMAN	Homo sapiens	3	0.7818
Phosphatidylinositol 5-phosphate 4-kinase type-2 beta	P78356	PI42B_HUMAN	Homo sapiens	3	0.7817
Phosphatidylinositol 5-phosphate 4-kinase type-2 beta	P78356	PI42B_HUMAN	Homo sapiens	3	0.7817
Mitogen-activated protein kinase 14	Q16539	MK14_HUMAN	Homo sapiens	3	0.7807
Mitogen-activated protein kinase 14	Q16539	MK14_HUMAN	Homo sapiens	3	0.7807
Coagulation factor X	P00742	FA10_HUMAN	Homo sapiens	3	0.7790
Coagulation factor X	P00742	FA10_HUMAN	Homo sapiens	3	0.7790
Trichothecene 15-O-acetyltransferase TRI3	Q9C1B7	TRI3_FUSSP	Fusarium sporotrichioides	3	0.7789
Trichothecene 15-O-acetyltransferase TRI3	Q9C1B7	TRI3_FUSSP	Fusarium sporotrichioides	3	0.7789
DNA topoisomerase 4 subunit B	H7C794	PARE_ENTFA	Enterococcus faecalis	3	0.7778
DNA topoisomerase 4 subunit B	H7C794	PARE_ENTFA	Enterococcus faecalis	3	0.7778
Tyrosine-protein kinase JAK2	O60674	JAK2_HUMAN	Homo sapiens	3	0.7771
ALK tyrosine kinase receptor	Q9UM73	ALK_HUMAN	Homo sapiens	3	0.7771
Tyrosine-protein kinase JAK2	O60674	JAK2_HUMAN	Homo sapiens	3	0.7771
ALK tyrosine kinase receptor	Q9UM73	ALK_HUMAN	Homo sapiens	3	0.7771
Purine nucleoside phosphorylase	P00491	PNPH_HUMAN	Homo sapiens	3	0.7761
Purine nucleoside phosphorylase	P00491	PNPH_HUMAN	Homo sapiens	3	0.7761
Macrophage colony-stimulating factor 1 receptor	P07333	CSF1R_HUMAN	Homo sapiens	3	0.7748
Macrophage colony-stimulating factor 1 receptor	P07333	CSF1R_HUMAN	Homo sapiens	3	0.7748
Seminal ribonuclease	P00669	RNS_BOVIN	Bos taurus	3	0.7740
Seminal ribonuclease	P00669	RNS_BOVIN	Bos taurus	3	0.7740
Mitogen-activated protein kinase 14	Q16539	MK14_HUMAN	Homo sapiens	3	0.7737
Mitogen-activated protein kinase 14	Q16539	MK14_HUMAN	Homo sapiens	3	0.7737
Purine nucleoside phosphorylase DeoD-type	Q5EEL8	DEOD_BACCE	Bacillus cereus	3	0.7735
Purine nucleoside phosphorylase DeoD-type	Q5EEL8	DEOD_BACCE	Bacillus cereus	3	0.7735
Mitogen-activated protein kinase 14	Q16539	MK14_HUMAN	Homo sapiens	3	0.7731
Mitogen-activated protein kinase 14	Q16539	MK14_HUMAN	Homo sapiens	3	0.7731
Peroxisome proliferator-activated receptor gamma	P37231	PPARG_HUMAN	Homo sapiens	3	0.7730
Peroxisome proliferator-activated receptor gamma	P37231	PPARG_HUMAN	Homo sapiens	3	0.7730
Nuclear receptor subfamily 1 group I member 2	O75469	NR1I2_HUMAN	Homo sapiens	3	0.7729
Nuclear receptor subfamily 1 group I member 2	O75469	NR1I2_HUMAN	Homo sapiens	3	0.7729
Beta-secretase 1	P56817	BACE1_HUMAN	Homo sapiens	2	0.7728
Beta-secretase 1	P56817	BACE1_HUMAN	Homo sapiens	2	0.7728
Adenosine kinase	Q9TVW2	ADK_TOXGO	Toxoplasma gondii	3	0.7717
Adenosine kinase	Q9TVW2	ADK_TOXGO	Toxoplasma gondii	3	0.7717
Queuine tRNA-ribosyltransferase	P28720	TGT_ZYMMO	Zymomonas mobilis subsp. mobilis	3	0.7711
Queuine tRNA-ribosyltransferase	P28720	TGT_ZYMMO	Zymomonas mobilis subsp. mobilis	3	0.7711
Genome polyprotein	C0LMU0	C0LMU0_9FLAV	dengue virus type 3	3	0.7699
Genome polyprotein	C0LMU0	C0LMU0_9FLAV	dengue virus type 3	3	0.7699
S-norcoclaurine synthase	Q67A25	NCS_THLFG	Thalictrum flavum subsp. glaucum	3	0.7696
S-norcoclaurine synthase	Q67A25	NCS_THLFG	Thalictrum flavum subsp. glaucum	3	0.7696
NAD(P)H-hydrate epimerase	Q8K4Z3	NNRE_MOUSE	Mus musculus	3	0.7692
NAD(P)H-hydrate epimerase	Q8K4Z3	NNRE_MOUSE	Mus musculus	3	0.7692
Dual specificity mitogen-activated protein kinase kinase 1	Q02750	MP2K1_HUMAN	Homo sapiens	3	0.7690
Dual specificity mitogen-activated protein kinase kinase 1	Q02750	MP2K1_HUMAN	Homo sapiens	3	0.7690
S-adenosylmethionine decarboxylase proenzyme	P17707	DCAM_HUMAN	Homo sapiens	3	0.7676
S-adenosylmethionine decarboxylase proenzyme	P17707	DCAM_HUMAN	Homo sapiens	3	0.7676
Beta-secretase 1	P56817	BACE1_HUMAN	Homo sapiens	3	0.7676
Beta-secretase 1	P56817	BACE1_HUMAN	Homo sapiens	3	0.7676
Gag-Pol polyprotein	P12497	POL_HV1N5	Human immunodeficiency virus type 1 group M subtype B	3	0.7664
Gag-Pol polyprotein	P12497	POL_HV1N5	Human immunodeficiency virus type 1 group M subtype B	3	0.7664
Heat shock protein HSP 90-alpha	P07900	HS90A_HUMAN	Homo sapiens	3	0.7660
Heat shock protein HSP 90-alpha	P07900	HS90A_HUMAN	Homo sapiens	3	0.7660
ALK tyrosine kinase receptor	Q9UM73	ALK_HUMAN	Homo sapiens	3	0.7655
ALK tyrosine kinase receptor	Q9UM73	ALK_HUMAN	Homo sapiens	3	0.7655
Heat shock protein HSP 90-alpha	P07900	HS90A_HUMAN	Homo sapiens	3	0.7655
Heat shock protein HSP 90-alpha	P07900	HS90A_HUMAN	Homo sapiens	3	0.7655
Pentaerythritol tetranitrate reductase	P71278	P71278_ENTCL	Enterobacter cloacae	2	0.7654
Pentaerythritol tetranitrate reductase	P71278	P71278_ENTCL	Enterobacter cloacae	2	0.7654
HTH-type transcriptional repressor PurR	P0ACP7	PURR_ECOLI	Escherichia coli	3	0.7652
HTH-type transcriptional repressor PurR	P0ACP7	PURR_ECOLI	Escherichia coli	3	0.7652
APH(2'')-Id	O68183	O68183_ENTCA	Enterococcus casseliflavus	3	0.7651
APH(2'')-Id	O68183	O68183_ENTCA	Enterococcus casseliflavus	3	0.7651
Elongation factor Tu 1	P0CE47	EFTU1_ECOLI	Escherichia coli	3	0.7651
Elongation factor Tu 1	P0CE47	EFTU1_ECOLI	Escherichia coli	3	0.7651
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4	Q9Y3Q4	HCN4_HUMAN	Homo sapiens	4	0.7648
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4	Q9Y3Q4	HCN4_HUMAN	Homo sapiens	4	0.7648
Cyclin-dependent kinase 9	P50750	CDK9_HUMAN	Homo sapiens	3	0.7648
Cyclin-dependent kinase 9	P50750	CDK9_HUMAN	Homo sapiens	3	0.7648
HTH-type transcriptional repressor PurR	P0ACP7	PURR_ECOLI	Escherichia coli	3	0.7647
HTH-type transcriptional repressor PurR	P0ACP7	PURR_ECOLI	Escherichia coli	3	0.7647
DNA-binding transcriptional dual regulator CRP	P0ACJ8	CRP_ECOLI	Escherichia coli	4	0.7636
DNA-binding transcriptional dual regulator CRP	P0ACJ8	CRP_ECOLI	Escherichia coli	4	0.7636
HTH-type transcriptional repressor PurR	P0ACP7	PURR_ECOLI	Escherichia coli	3	0.7634
HTH-type transcriptional repressor PurR	P0ACP7	PURR_ECOLI	Escherichia coli	3	0.7634
S-methyl-5'-thioadenosine phosphorylase	Q97W94	MTAP_SACS2	Saccharolobus solfataricus	3	0.7630
S-methyl-5'-thioadenosine phosphorylase	Q97W94	MTAP_SACS2	Saccharolobus solfataricus	3	0.7630
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	P48736	PK3CG_HUMAN	Homo sapiens	4	0.7627
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	P48736	PK3CG_HUMAN	Homo sapiens	4	0.7627
Protein mono-ADP-ribosyltransferase PARP3	Q9Y6F1	PARP3_HUMAN	Homo sapiens	3	0.7626
Protein mono-ADP-ribosyltransferase PARP3	Q9Y6F1	PARP3_HUMAN	Homo sapiens	3	0.7626
Nitric oxide synthase, inducible	P29477	NOS2_MOUSE	Mus musculus	3	0.7624
Nitric oxide synthase, inducible	P29477	NOS2_MOUSE	Mus musculus	3	0.7624
Prothrombin	P00734	THRB_HUMAN	Homo sapiens	3	0.7623
Beta-1 adrenergic receptor	P07700	ADRB1_MELGA	Meleagris gallopavo	3	0.7623
Prothrombin	P00734	THRB_HUMAN	Homo sapiens	3	0.7623
Beta-1 adrenergic receptor	P07700	ADRB1_MELGA	Meleagris gallopavo	3	0.7623
Purine nucleoside phosphorylase DeoD-type	P0ABP9	DEOD_ECO57	Escherichia coli O157:H7	3	0.7619
Purine nucleoside phosphorylase DeoD-type	P0ABP9	DEOD_ECO57	Escherichia coli O157:H7	3	0.7619
Urokinase-type plasminogen activator	P00749	UROK_HUMAN	Homo sapiens	3	0.7618
Urokinase-type plasminogen activator	P00749	UROK_HUMAN	Homo sapiens	3	0.7618
Flavin reductase like domain-containing protein	Q4UKE8	Q4UKE8_RICFE	Rickettsia felis	3	0.7617
Flavin reductase like domain-containing protein	Q4UKE8	Q4UKE8_RICFE	Rickettsia felis	3	0.7617
Beta-secretase 1	P56817	BACE1_HUMAN	Homo sapiens	3	0.7610
Beta-secretase 1	P56817	BACE1_HUMAN	Homo sapiens	3	0.7610
Poly [ADP-ribose] polymerase 1	P09874	PARP1_HUMAN	Homo sapiens	3	0.7601
Poly [ADP-ribose] polymerase 1	P09874	PARP1_HUMAN	Homo sapiens	3	0.7601
Beta-secretase 1	P56817	BACE1_HUMAN	Homo sapiens	3	0.7599
Beta-secretase 1	P56817	BACE1_HUMAN	Homo sapiens	3	0.7599
Fibroblast growth factor receptor 2	P21802	FGFR2_HUMAN	Homo sapiens	3	0.7597
Fibroblast growth factor receptor 2	P21802	FGFR2_HUMAN	Homo sapiens	3	0.7597
Queuine tRNA-ribosyltransferase	P28720	TGT_ZYMMO	Zymomonas mobilis subsp. mobilis	4	0.7595
Queuine tRNA-ribosyltransferase	P28720	TGT_ZYMMO	Zymomonas mobilis subsp. mobilis	4	0.7595
Soluble cytochrome b562	P0ABE7	C562_ECOLX	Escherichia coli	3	0.7593
Soluble cytochrome b562	P0ABE7	C562_ECOLX	Escherichia coli	3	0.7593
Prothrombin	P00734	THRB_HUMAN	Homo sapiens	3	0.7591
Prothrombin	P00734	THRB_HUMAN	Homo sapiens	3	0.7591
Chaperone protein ClpB	Q9RA63	CLPB_THET8	Thermus thermophilus	3	0.7585
Chaperone protein ClpB	Q9RA63	CLPB_THET8	Thermus thermophilus	3	0.7585
Mitogen-activated protein kinase 14	Q16539	MK14_HUMAN	Homo sapiens	3	0.7584
Mitogen-activated protein kinase 14	Q16539	MK14_HUMAN	Homo sapiens	3	0.7584
Purine nucleoside phosphorylase DeoD-type	P0ABP9	DEOD_ECO57	Escherichia coli O157:H7	3	0.7581
Purine nucleoside phosphorylase DeoD-type	P0ABP9	DEOD_ECO57	Escherichia coli O157:H7	3	0.7581
Prothrombin	P00734	THRB_HUMAN	Homo sapiens	3	0.7579
Prothrombin	P00734	THRB_HUMAN	Homo sapiens	3	0.7579
7-methylguanosine phosphate-specific 5'-nucleotidase	Q9W197	5NT3B_DROME	Drosophila melanogaster	3	0.7575
7-methylguanosine phosphate-specific 5'-nucleotidase	Q9W197	5NT3B_DROME	Drosophila melanogaster	3	0.7575
Matrix metalloproteinase-20	O60882	MMP20_HUMAN	Homo sapiens	3	0.7574
Matrix metalloproteinase-20	O60882	MMP20_HUMAN	Homo sapiens	3	0.7574
Queuine tRNA-ribosyltransferase	P28720	TGT_ZYMMO	Zymomonas mobilis subsp. mobilis	3	0.7569
Neprilysin	P08473	NEP_HUMAN	Homo sapiens	4	0.7569
Queuine tRNA-ribosyltransferase	P28720	TGT_ZYMMO	Zymomonas mobilis subsp. mobilis	3	0.7569
Neprilysin	P08473	NEP_HUMAN	Homo sapiens	4	0.7569
Thymidylate synthase	P00469	TYSY_LACCA	Lacticaseibacillus casei	3	0.7566
Thymidylate synthase	P00469	TYSY_LACCA	Lacticaseibacillus casei	3	0.7566
Deoxycytidine kinase	P27707	DCK_HUMAN	Homo sapiens	3	0.7553
Purine nucleoside phosphorylase	Q8I3X4	Q8I3X4_PLAF7	Plasmodium falciparum	3	0.7553
Deoxycytidine kinase	P27707	DCK_HUMAN	Homo sapiens	3	0.7553
Purine nucleoside phosphorylase	Q8I3X4	Q8I3X4_PLAF7	Plasmodium falciparum	3	0.7553
Purine nucleoside phosphorylase DeoD-type	Q5EEL8	DEOD_BACCE	Bacillus cereus	3	0.7550
Purine nucleoside phosphorylase DeoD-type	Q5EEL8	DEOD_BACCE	Bacillus cereus	3	0.7550
Casein kinase II subunit alpha	P68400	CSK21_HUMAN	Homo sapiens	3	0.7547
Casein kinase II subunit alpha	P68400	CSK21_HUMAN	Homo sapiens	3	0.7547
Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplastic	Q43088	RBCMT_PEA	Pisum sativum	3	0.7542
Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplastic	Q43088	RBCMT_PEA	Pisum sativum	3	0.7542
Nitric oxide synthase oxygenase	O34453	NOSO_BACSU	Bacillus subtilis	3	0.7538
Nitric oxide synthase oxygenase	O34453	NOSO_BACSU	Bacillus subtilis	3	0.7538
Prothrombin	P00734	THRB_HUMAN	Homo sapiens	3	0.7535
Prothrombin	P00734	THRB_HUMAN	Homo sapiens	3	0.7535
Tyrosine-protein kinase JAK2	O60674	JAK2_HUMAN	Homo sapiens	4	0.7526
Tyrosine-protein kinase JAK2	O60674	JAK2_HUMAN	Homo sapiens	4	0.7526
Genome polyprotein	A0EKU1	A0EKU1_9FLAV	Meaban virus	3	0.7512
N-acetylhexosamine 1-kinase	E8MF12	NAHK_BIFL2	Bifidobacterium longum subsp. longum	3	0.7512
N-acetylhexosamine 1-kinase	E8MF12	NAHK_BIFL2	Bifidobacterium longum subsp. longum	3	0.7512
Genome polyprotein	A0EKU1	A0EKU1_9FLAV	Meaban virus	3	0.7512
cGMP-dependent 3',5'-cyclic phosphodiesterase	O00408	PDE2A_HUMAN	Homo sapiens	3	0.7501
cGMP-dependent 3',5'-cyclic phosphodiesterase	O00408	PDE2A_HUMAN	Homo sapiens	3	0.7501
Steroid C26-monooxygenase	P9WPP1	CP125_MYCTU	Mycobacterium tuberculosis	3	0.7497
Steroid C26-monooxygenase	P9WPP1	CP125_MYCTU	Mycobacterium tuberculosis	3	0.7497
Deoxycytidine kinase	P27707	DCK_HUMAN	Homo sapiens	3	0.7496
Photosynthetic reaction center cytochrome c subunit	P07173	CYCR_BLAVI	Blastochloris viridis	2	0.7496
Photosynthetic reaction center cytochrome c subunit	P07173	CYCR_BLAVI	Blastochloris viridis	2	0.7496
Deoxycytidine kinase	P27707	DCK_HUMAN	Homo sapiens	3	0.7496
Methylmalonyl-CoA decarboxylase	P52045	SCPB_ECOLI	Escherichia coli	3	0.7493
Methylmalonyl-CoA decarboxylase	P52045	SCPB_ECOLI	Escherichia coli	3	0.7493
Albumin	P02768	ALBU_HUMAN	Homo sapiens	3	0.7491
Albumin	P02768	ALBU_HUMAN	Homo sapiens	3	0.7491
Acyl-CoA:acyl-CoA alkyltransferase	Q8PDX2	OLEA_XANCP	Xanthomonas campestris pv. campestris	3	0.7489
Acyl-CoA:acyl-CoA alkyltransferase	Q8PDX2	OLEA_XANCP	Xanthomonas campestris pv. campestris	3	0.7489
Nitric oxide synthase, inducible	P29477	NOS2_MOUSE	Mus musculus	3	0.7487
Nitric oxide synthase, inducible	P29477	NOS2_MOUSE	Mus musculus	3	0.7487
Purine nucleoside phosphorylase DeoD-type	P0ABP9	DEOD_ECO57	Escherichia coli O157:H7	3	0.7482
Purine nucleoside phosphorylase DeoD-type	P0ABP9	DEOD_ECO57	Escherichia coli O157:H7	3	0.7482
Precorrin-3 methylase	O68097	O68097_RHOCA	Rhodobacter capsulatus	3	0.7478
Precorrin-3 methylase	O68097	O68097_RHOCA	Rhodobacter capsulatus	3	0.7478
chitinase	B0Y2Y2	B0Y2Y2_ASPFC	Aspergillus fumigatus	3	0.7478
chitinase	B0Y2Y2	B0Y2Y2_ASPFC	Aspergillus fumigatus	3	0.7478
3',5'-cyclic-AMP phosphodiesterase 4B	Q07343	PDE4B_HUMAN	Homo sapiens	3	0.7475
3',5'-cyclic-AMP phosphodiesterase 4B	Q07343	PDE4B_HUMAN	Homo sapiens	3	0.7475
Beta-1 adrenergic receptor	P07700	ADRB1_MELGA	Meleagris gallopavo	3	0.7471
Mitogen-activated protein kinase 8	P45983	MK08_HUMAN	Homo sapiens	3	0.7471
Mitogen-activated protein kinase 8	P45983	MK08_HUMAN	Homo sapiens	3	0.7471
Beta-1 adrenergic receptor	P07700	ADRB1_MELGA	Meleagris gallopavo	3	0.7471
HTH-type transcriptional repressor PurR	P0ACP7	PURR_ECOLI	Escherichia coli	3	0.7464
HTH-type transcriptional repressor PurR	P0ACP7	PURR_ECOLI	Escherichia coli	3	0.7464
Tetracycline repressor protein class D	P0ACT4	TETR4_ECOLX	Escherichia coli	3	0.7463
Genome polyprotein	P29991	POLG_DEN27	Dengue virus type 2	3	0.7463
Genome polyprotein	P29991	POLG_DEN27	Dengue virus type 2	3	0.7463
Tetracycline repressor protein class D	P0ACT4	TETR4_ECOLX	Escherichia coli	3	0.7463
Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase	Q05603	COBT_SALTY	Salmonella typhimurium	2	0.7461
Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase	Q05603	COBT_SALTY	Salmonella typhimurium	2	0.7461
Endoplasmin	P41148	ENPL_CANLF	Canis lupus familiaris	3	0.7459
Endoplasmin	P41148	ENPL_CANLF	Canis lupus familiaris	3	0.7459
Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplastic	Q43088	RBCMT_PEA	Pisum sativum	3	0.7456
Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplastic	Q43088	RBCMT_PEA	Pisum sativum	3	0.7456
2',3'-cyclic-nucleotide 3'-phosphodiesterase	P16330	CN37_MOUSE	Mus musculus	3	0.7455
2',3'-cyclic-nucleotide 3'-phosphodiesterase	P16330	CN37_MOUSE	Mus musculus	3	0.7455
Purine nucleoside phosphorylase DeoD-type	P0ABP8	DEOD_ECOLI	Escherichia coli	3	0.7448
Purine nucleoside phosphorylase DeoD-type	P0ABP8	DEOD_ECOLI	Escherichia coli	3	0.7448
Poly [ADP-ribose] polymerase tankyrase-2	Q9H2K2	TNKS2_HUMAN	Homo sapiens	3	0.7447
Poly [ADP-ribose] polymerase tankyrase-2	Q9H2K2	TNKS2_HUMAN	Homo sapiens	3	0.7447
Beta-secretase 1	P56817	BACE1_HUMAN	Homo sapiens	3	0.7445
Beta-secretase 1	P56817	BACE1_HUMAN	Homo sapiens	3	0.7445
Nitric oxide synthase, inducible	P29477	NOS2_MOUSE	Mus musculus	3	0.7439
Nitric oxide synthase, inducible	P29477	NOS2_MOUSE	Mus musculus	3	0.7439
Prothrombin	P00734	THRB_HUMAN	Homo sapiens	2	0.7438
Prothrombin	P00734	THRB_HUMAN	Homo sapiens	2	0.7438
Maltokinase	A1TH50	MAK_MYCVP	Mycolicibacterium vanbaalenii	3	0.7434
Maltokinase	A1TH50	MAK_MYCVP	Mycolicibacterium vanbaalenii	3	0.7434
YbaK/aminoacyl-tRNA synthetase-associated domain-containing protein	Q5SHN1	Q5SHN1_THET8	Thermus thermophilus	3	0.7432
YbaK/aminoacyl-tRNA synthetase-associated domain-containing protein	Q5SHN1	Q5SHN1_THET8	Thermus thermophilus	3	0.7432
CCA-adding enzyme	O28126	CCA_ARCFU	Archaeoglobus fulgidus	2	0.7430
CCA-adding enzyme	O28126	CCA_ARCFU	Archaeoglobus fulgidus	2	0.7430
Endoplasmic reticulum aminopeptidase 2	Q6P179	ERAP2_HUMAN	Homo sapiens	2	0.7426
Endoplasmic reticulum aminopeptidase 2	Q6P179	ERAP2_HUMAN	Homo sapiens	2	0.7426
Vanillyl-alcohol oxidase	P56216	VAOX_PENSI	Penicillium simplicissimum	3	0.7425
Vanillyl-alcohol oxidase	P56216	VAOX_PENSI	Penicillium simplicissimum	3	0.7425
Formate--tetrahydrofolate ligase	Q2RM91	FTHS_MOOTA	Moorella thermoacetica	2	0.7418
Formate--tetrahydrofolate ligase	Q2RM91	FTHS_MOOTA	Moorella thermoacetica	2	0.7418
Signaling protein	P83820	P83820_THETH	Thermus thermophilus	3	0.7416
Signaling protein	P83820	P83820_THETH	Thermus thermophilus	3	0.7416
cAMP-dependent protein kinase catalytic subunit alpha	P00517	KAPCA_BOVIN	Bos taurus	3	0.7415
cAMP-dependent protein kinase catalytic subunit alpha	P00517	KAPCA_BOVIN	Bos taurus	3	0.7415
Purine phosphoribosyltransferase (GpT-1)	Q97W95	Q97W95_SACS2	Saccharolobus solfataricus	3	0.7414
Purine phosphoribosyltransferase (GpT-1)	Q97W95	Q97W95_SACS2	Saccharolobus solfataricus	3	0.7414
Nickel-binding periplasmic protein	P33590	NIKA_ECOLI	Escherichia coli	2	0.7412
Nickel-binding periplasmic protein	P33590	NIKA_ECOLI	Escherichia coli	2	0.7412
Soluble cytochrome b562	P0ABE7	C562_ECOLX	Escherichia coli	3	0.7409
Catechol O-methyltransferase	P22734	COMT_RAT	Rattus norvegicus	3	0.7409
Glucose-1-phosphate thymidylyltransferase	Q9HU22	Q9HU22_PSEAE	Pseudomonas aeruginosa	4	0.7409
Soluble cytochrome b562	P0ABE7	C562_ECOLX	Escherichia coli	3	0.7409
Dihydrofolate reductase	P0ABQ4	DYR_ECOLI	Escherichia coli	4	0.7409
Catechol O-methyltransferase	P22734	COMT_RAT	Rattus norvegicus	3	0.7409
Glucose-1-phosphate thymidylyltransferase	Q9HU22	Q9HU22_PSEAE	Pseudomonas aeruginosa	4	0.7409
Dihydrofolate reductase	P0ABQ4	DYR_ECOLI	Escherichia coli	4	0.7409
HTH-type transcriptional regulator TtgR	Q9AIU0	TTGR_PSEPT	Pseudomonas putida	3	0.7408
HTH-type transcriptional regulator TtgR	Q9AIU0	TTGR_PSEPT	Pseudomonas putida	3	0.7408
Histone-lysine N-methyltransferase EHMT1	Q9H9B1	EHMT1_HUMAN	Homo sapiens	3	0.7407
Histone-lysine N-methyltransferase EHMT1	Q9H9B1	EHMT1_HUMAN	Homo sapiens	3	0.7407
Genome polyprotein	A9LIE0	A9LIE0_9FLAV	dengue virus type 3	3	0.7403
Genome polyprotein	A9LIE0	A9LIE0_9FLAV	dengue virus type 3	3	0.7403
3-hydroxyanthranilate 3,4-dioxygenase	Q1LCS4	3HAO_CUPMC	Cupriavidus metallidurans	2	0.7402
3-hydroxyanthranilate 3,4-dioxygenase	Q1LCS4	3HAO_CUPMC	Cupriavidus metallidurans	2	0.7402
Tyrosine-protein kinase JAK1	P23458	JAK1_HUMAN	Homo sapiens	3	0.7398
Tyrosine-protein kinase JAK1	P23458	JAK1_HUMAN	Homo sapiens	3	0.7398
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A	Q9Y233	PDE10_HUMAN	Homo sapiens	3	0.7398
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A	Q9Y233	PDE10_HUMAN	Homo sapiens	3	0.7398
Cytochrome P450 1A1	P04798	CP1A1_HUMAN	Homo sapiens	3	0.7397
Tyrosine-protein kinase JAK1	P23458	JAK1_HUMAN	Homo sapiens	3	0.7397
Tyrosine-protein kinase JAK1	P23458	JAK1_HUMAN	Homo sapiens	3	0.7397
(R)-S-adenosyl-L-methionine hydrolase	O58212	O58212_PYRHO	Pyrococcus horikoshii OT3	3	0.7397
Cytochrome P450 1A1	P04798	CP1A1_HUMAN	Homo sapiens	3	0.7397
(R)-S-adenosyl-L-methionine hydrolase	O58212	O58212_PYRHO	Pyrococcus horikoshii OT3	3	0.7397
Nitric oxide synthase 1	P29476	NOS1_RAT	Rattus norvegicus	3	0.7396
Genome polyprotein	Q8QL64	Q8QL64_9FLAV	Modoc virus	3	0.7396
Nitric oxide synthase 1	P29476	NOS1_RAT	Rattus norvegicus	3	0.7396
Genome polyprotein	Q8QL64	Q8QL64_9FLAV	Modoc virus	3	0.7396
Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplastic	Q43088	RBCMT_PEA	Pisum sativum	3	0.7395
Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplastic	Q43088	RBCMT_PEA	Pisum sativum	3	0.7395
Endoplasmin	P41148	ENPL_CANLF	Canis lupus familiaris	3	0.7389
Endoplasmin	P41148	ENPL_CANLF	Canis lupus familiaris	3	0.7389
Heat shock protein HSP 90-alpha	P07900	HS90A_HUMAN	Homo sapiens	3	0.7389
Heat shock protein HSP 90-alpha	P07900	HS90A_HUMAN	Homo sapiens	3	0.7389
Cystathionine beta-lyase MetC	P06721	METC_ECOLI	Escherichia coli	3	0.7386
Cystathionine beta-lyase MetC	P06721	METC_ECOLI	Escherichia coli	3	0.7386
uroporphyrinogen-III C-methyltransferase	P95417	P95417_PSEAI	Pseudomonas aeruginosa	3	0.7385
uroporphyrinogen-III C-methyltransferase	P95417	P95417_PSEAI	Pseudomonas aeruginosa	3	0.7385
Queuine tRNA-ribosyltransferase	P28720	TGT_ZYMMO	Zymomonas mobilis subsp. mobilis	3	0.7375
Nitric oxide synthase, inducible	P29477	NOS2_MOUSE	Mus musculus	3	0.7375
Queuine tRNA-ribosyltransferase	P28720	TGT_ZYMMO	Zymomonas mobilis subsp. mobilis	3	0.7375
Nitric oxide synthase, inducible	P29477	NOS2_MOUSE	Mus musculus	3	0.7375
Nitric oxide synthase, inducible	P29477	NOS2_MOUSE	Mus musculus	3	0.7374
Bifunctional dihydrofolate reductase-thymidylate synthase	Q07422	DRTS_TOXGO	Toxoplasma gondii	3	0.7374
Nitric oxide synthase, inducible	P29477	NOS2_MOUSE	Mus musculus	3	0.7374
Bifunctional dihydrofolate reductase-thymidylate synthase	Q07422	DRTS_TOXGO	Toxoplasma gondii	3	0.7374
Prothrombin	P00734	THRB_HUMAN	Homo sapiens	3	0.7372
Prothrombin	P00734	THRB_HUMAN	Homo sapiens	3	0.7372
16S rRNA (adenine(1408)-N(1))-methyltransferase	A8C927	NPMA_ECOLX	Escherichia coli	3	0.7372
16S rRNA (adenine(1408)-N(1))-methyltransferase	A8C927	NPMA_ECOLX	Escherichia coli	3	0.7372
tRNA-guanine(15) transglycosylase	O58843	ATGT_PYRHO	Pyrococcus horikoshii	3	0.7369
tRNA-guanine(15) transglycosylase	O58843	ATGT_PYRHO	Pyrococcus horikoshii	3	0.7369
Serine/threonine-protein kinase Chk1	O14757	CHK1_HUMAN	Homo sapiens	3	0.7366
Serine/threonine-protein kinase Chk1	O14757	CHK1_HUMAN	Homo sapiens	3	0.7366
Formylmethanofuran--tetrahydromethanopterin formyltransferase	Q49610	FTR_METKA	Methanopyrus kandleri	3	0.7365
Formylmethanofuran--tetrahydromethanopterin formyltransferase	Q49610	FTR_METKA	Methanopyrus kandleri	3	0.7365
Polymerase acidic protein	C3W5S0	C3W5S0_I09A0	Influenza A virus	2	0.7364
Polymerase acidic protein	C3W5S0	C3W5S0_I09A0	Influenza A virus	2	0.7364
HTH-type transcriptional repressor PurR	P0ACP7	PURR_ECOLI	Escherichia coli	2	0.7362
Fibroblast growth factor receptor 2	P21802	FGFR2_HUMAN	Homo sapiens	3	0.7362
HTH-type transcriptional repressor PurR	P0ACP7	PURR_ECOLI	Escherichia coli	2	0.7362
Fibroblast growth factor receptor 2	P21802	FGFR2_HUMAN	Homo sapiens	3	0.7362
SRSF protein kinase 1	Q96SB4	SRPK1_HUMAN	Homo sapiens	3	0.7359
SRSF protein kinase 1	Q96SB4	SRPK1_HUMAN	Homo sapiens	3	0.7359
Mycinamicin III 3''-O-methyltransferase	Q49492	MYCF_MICGR	Micromonospora griseorubida	2	0.7357
Mycinamicin III 3''-O-methyltransferase	Q49492	MYCF_MICGR	Micromonospora griseorubida	2	0.7357
Thymidylate synthase	P00469	TYSY_LACCA	Lacticaseibacillus casei	3	0.7356
Thymidylate synthase	P00469	TYSY_LACCA	Lacticaseibacillus casei	3	0.7356
Phosphodiesterase	Q8WQX9	Q8WQX9_9TRYP	Trypanosoma brucei	3	0.7353
Phosphodiesterase	Q8WQX9	Q8WQX9_9TRYP	Trypanosoma brucei	3	0.7353
Histone-lysine N-methyltransferase SETD7	Q8WTS6	SETD7_HUMAN	Homo sapiens	3	0.7349
Histone-lysine N-methyltransferase SETD7	Q8WTS6	SETD7_HUMAN	Homo sapiens	3	0.7349
Purine nucleoside phosphorylase DeoD-type	O34925	DEOD_BACSU	Bacillus subtilis	3	0.7343
Purine nucleoside phosphorylase DeoD-type	O34925	DEOD_BACSU	Bacillus subtilis	3	0.7343
Mitogen-activated protein kinase kinase kinase 7	O43318	M3K7_HUMAN	Homo sapiens	3	0.7340
Mitogen-activated protein kinase kinase kinase 7	O43318	M3K7_HUMAN	Homo sapiens	3	0.7340
Epidermal growth factor receptor	P00533	EGFR_HUMAN	Homo sapiens	3	0.7333
Epidermal growth factor receptor	P00533	EGFR_HUMAN	Homo sapiens	3	0.7333
Epidermal growth factor receptor	P00533	EGFR_HUMAN	Homo sapiens	3	0.7332
Epidermal growth factor receptor	P00533	EGFR_HUMAN	Homo sapiens	3	0.7332
HTH-type transcriptional regulator TtgR	Q9AIU0	TTGR_PSEPT	Pseudomonas putida	3	0.7327
HTH-type transcriptional regulator TtgR	Q9AIU0	TTGR_PSEPT	Pseudomonas putida	3	0.7327
Histone-lysine N-methyltransferase EHMT2	Q96KQ7	EHMT2_HUMAN	Homo sapiens	3	0.7320
Histone-lysine N-methyltransferase EHMT2	Q96KQ7	EHMT2_HUMAN	Homo sapiens	3	0.7320
Mismatch repair endonuclease PMS2	P54278	PMS2_HUMAN	Homo sapiens	3	0.7317
LD-carboxypeptidase	A0A6L8PVW7	A0A1Q4LWC0_BACAN	Bacillus anthracis	3	0.7317
Mismatch repair endonuclease PMS2	P54278	PMS2_HUMAN	Homo sapiens	3	0.7317
HTH-type transcriptional repressor PurR	P0ACP7	PURR_ECOLI	Escherichia coli	3	0.7317
Pancreatic alpha-amylase	P04746	AMYP_HUMAN	Homo sapiens	2	0.7317
LD-carboxypeptidase	A0A6L8PVW7	A0A1Q4LWC0_BACAN	Bacillus anthracis	3	0.7317
HTH-type transcriptional repressor PurR	P0ACP7	PURR_ECOLI	Escherichia coli	3	0.7317
Pancreatic alpha-amylase	P04746	AMYP_HUMAN	Homo sapiens	2	0.7317
Poly [ADP-ribose] polymerase 1	P09874	PARP1_HUMAN	Homo sapiens	3	0.7315
Poly [ADP-ribose] polymerase 1	P09874	PARP1_HUMAN	Homo sapiens	3	0.7315
Aurora kinase A	O14965	AURKA_HUMAN	Homo sapiens	3	0.7314
Aurora kinase A	O14965	AURKA_HUMAN	Homo sapiens	3	0.7314
Casein kinase I isoform gamma-3	Q9Y6M4	KC1G3_HUMAN	Homo sapiens	4	0.7311
Casein kinase I isoform gamma-3	Q9Y6M4	KC1G3_HUMAN	Homo sapiens	4	0.7311
Uncharacterized protein YML079W	Q03629	YMH9_YEAST	Saccharomyces cerevisiae	2	0.7310
Uncharacterized protein YML079W	Q03629	YMH9_YEAST	Saccharomyces cerevisiae	2	0.7310
Pantothenate synthetase	P9WIL5	PANC_MYCTU	Mycobacterium tuberculosis	3	0.7310
Pantothenate synthetase	P9WIL5	PANC_MYCTU	Mycobacterium tuberculosis	3	0.7310
Serine/threonine-protein kinase Chk2	O96017	CHK2_HUMAN	Homo sapiens	3	0.7308
Serine/threonine-protein kinase Chk2	O96017	CHK2_HUMAN	Homo sapiens	3	0.7308
Vascular endothelial growth factor receptor 2	P35968	VGFR2_HUMAN	Homo sapiens	3	0.7307
Vascular endothelial growth factor receptor 2	P35968	VGFR2_HUMAN	Homo sapiens	3	0.7307
Polymerase acidic protein	C3W5S0	C3W5S0_I09A0	Influenza A virus	2	0.7306
Polymerase acidic protein	C3W5S0	C3W5S0_I09A0	Influenza A virus	2	0.7306
Mitogen-activated protein kinase 8	P45983	MK08_HUMAN	Homo sapiens	3	0.7303
Mitogen-activated protein kinase 8	P45983	MK08_HUMAN	Homo sapiens	3	0.7303
Prothrombin	P00734	THRB_HUMAN	Homo sapiens	3	0.7298
Prothrombin	P00734	THRB_HUMAN	Homo sapiens	3	0.7298
Tyrosine-protein kinase JAK1	P23458	JAK1_HUMAN	Homo sapiens	4	0.7293
Tyrosine-protein kinase JAK1	P23458	JAK1_HUMAN	Homo sapiens	4	0.7293
L-methionine gamma-lyase	P13254	MEGL_PSEPU	Pseudomonas putida	3	0.7292
Histone-lysine N-methyltransferase, H3 lysine-9 specific SUVH4	Q8GZB6	SUVH4_ARATH	Arabidopsis thaliana	3	0.7292
Histone-lysine N-methyltransferase, H3 lysine-9 specific SUVH4	Q8GZB6	SUVH4_ARATH	Arabidopsis thaliana	3	0.7292
L-methionine gamma-lyase	P13254	MEGL_PSEPU	Pseudomonas putida	3	0.7292
Histone-lysine N-methyltransferase EHMT1	Q9H9B1	EHMT1_HUMAN	Homo sapiens	3	0.7291
Histone-lysine N-methyltransferase EHMT1	Q9H9B1	EHMT1_HUMAN	Homo sapiens	3	0.7291
Serine/threonine-protein kinase 24	Q9Y6E0	STK24_HUMAN	Homo sapiens	3	0.7289
Serine/threonine-protein kinase 24	Q9Y6E0	STK24_HUMAN	Homo sapiens	3	0.7289
16S rRNA (guanine(1405)-N(7))-methyltransferase	Q763K9	Q763K9_ECOLX	Escherichia coli	3	0.7286
Queuine tRNA-ribosyltransferase	P28720	TGT_ZYMMO	Zymomonas mobilis subsp. mobilis	3	0.7286
16S rRNA (guanine(1405)-N(7))-methyltransferase	Q763K9	Q763K9_ECOLX	Escherichia coli	3	0.7286
Queuine tRNA-ribosyltransferase	P28720	TGT_ZYMMO	Zymomonas mobilis subsp. mobilis	3	0.7286
Prothrombin	P00734	THRB_HUMAN	Homo sapiens	3	0.7282
Prothrombin	P00734	THRB_HUMAN	Homo sapiens	3	0.7282
Stromelysin-1	P08254	MMP3_HUMAN	Homo sapiens	3	0.7280
Stromelysin-1	P08254	MMP3_HUMAN	Homo sapiens	3	0.7280
Avidin	P02701	AVID_CHICK	Gallus gallus	2	0.7280
Avidin	P02701	AVID_CHICK	Gallus gallus	2	0.7280
Prothrombin	P00734	THRB_HUMAN	Homo sapiens	3	0.7279
Tyrosine-protein kinase SYK	P43405	KSYK_HUMAN	Homo sapiens	4	0.7279
Tyrosine-protein kinase SYK	P43405	KSYK_HUMAN	Homo sapiens	4	0.7279
Prothrombin	P00734	THRB_HUMAN	Homo sapiens	3	0.7279
Serine/threonine-protein kinase CtkA	Q9ZKJ5	CTKA_HELPJ	Helicobacter pylori	3	0.7276
Serine/threonine-protein kinase CtkA	Q9ZKJ5	CTKA_HELPJ	Helicobacter pylori	3	0.7276
Methyltransferase	Q81E32	Q81E32_BACCR	Bacillus cereus	3	0.7273
Methyltransferase	Q81E32	Q81E32_BACCR	Bacillus cereus	3	0.7273
Queuine tRNA-ribosyltransferase	P28720	TGT_ZYMMO	Zymomonas mobilis subsp. mobilis	3	0.7270
Queuine tRNA-ribosyltransferase	P28720	TGT_ZYMMO	Zymomonas mobilis subsp. mobilis	3	0.7270
ATP-dependent protease ATPase subunit HslU	P43773	HSLU_HAEIN	Haemophilus influenzae	3	0.7268
ATP-dependent protease ATPase subunit HslU	P43773	HSLU_HAEIN	Haemophilus influenzae	3	0.7268
WxcM-like protein	Q12KT8	Q12KT8_SHEDO	Shewanella denitrificans	3	0.7265
WxcM-like protein	Q12KT8	Q12KT8_SHEDO	Shewanella denitrificans	3	0.7265
Lipoyl synthase 2	Q8DLC2	LIPA2_THEEB	Thermosynechococcus vestitus	4	0.7265
Lipoyl synthase 2	Q8DLC2	LIPA2_THEEB	Thermosynechococcus vestitus	4	0.7265
Cyclin-dependent kinase 8	P49336	CDK8_HUMAN	Homo sapiens	3	0.7264
Cyclin-dependent kinase 8	P49336	CDK8_HUMAN	Homo sapiens	3	0.7264
Histone-lysine N-methyltransferase 2A	Q03164	KMT2A_HUMAN	Homo sapiens	3	0.7259
Histone-lysine N-methyltransferase 2A	Q03164	KMT2A_HUMAN	Homo sapiens	3	0.7259
Endoplasmin	P41148	ENPL_CANLF	Canis lupus familiaris	3	0.7253
Endoplasmin	P41148	ENPL_CANLF	Canis lupus familiaris	3	0.7253
Prenyltransferase	Q4R2T2	Q4R2T2_STRC1	Streptomyces sp	3	0.7252
Prenyltransferase	Q4R2T2	Q4R2T2_STRC1	Streptomyces sp	3	0.7252
Probable enoyl-CoA hydratase EchA8	P9WNN9	ECHA8_MYCTU	Mycobacterium tuberculosis	3	0.7249
Probable enoyl-CoA hydratase EchA8	P9WNN9	ECHA8_MYCTU	Mycobacterium tuberculosis	3	0.7249
cAMP-dependent protein kinase catalytic subunit alpha	P00517	KAPCA_BOVIN	Bos taurus	4	0.7245
cAMP-dependent protein kinase catalytic subunit alpha	P00517	KAPCA_BOVIN	Bos taurus	4	0.7245
Histone-lysine N-methyltransferase 2C	Q8NEZ4	KMT2C_HUMAN	Homo sapiens	3	0.7241
Histone-lysine N-methyltransferase 2C	Q8NEZ4	KMT2C_HUMAN	Homo sapiens	3	0.7241
Myosin heavy chain kinase A	P42527	MHCKA_DICDI	Dictyostelium discoideum	3	0.7239
Myosin heavy chain kinase A	P42527	MHCKA_DICDI	Dictyostelium discoideum	3	0.7239
Nitric oxide synthase, inducible	P29477	NOS2_MOUSE	Mus musculus	3	0.7231
Nitric oxide synthase, inducible	P29477	NOS2_MOUSE	Mus musculus	3	0.7231
Rhodopsin kinase GRK1	P28327	GRK1_BOVIN	Bos taurus	3	0.7228
Nitric oxide synthase, inducible	P29477	NOS2_MOUSE	Mus musculus	3	0.7228
Nitric oxide synthase, inducible	P29477	NOS2_MOUSE	Mus musculus	3	0.7228
Rhodopsin kinase GRK1	P28327	GRK1_BOVIN	Bos taurus	3	0.7228
Bifunctional epoxide hydrolase 2	P34913	HYES_HUMAN	Homo sapiens	3	0.7227
Bifunctional epoxide hydrolase 2	P34913	HYES_HUMAN	Homo sapiens	3	0.7227
Petrobactin biosynthesis protein AsbB	Q81RQ8	Q81RQ8_BACAN	Bacillus anthracis	3	0.7223
5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase 1	O50008	METE1_ARATH	Arabidopsis thaliana	2	0.7223
Petrobactin biosynthesis protein AsbB	Q81RQ8	Q81RQ8_BACAN	Bacillus anthracis	3	0.7223
5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase 1	O50008	METE1_ARATH	Arabidopsis thaliana	2	0.7223
Disks large homolog 1	Q12959	DLG1_HUMAN	Homo sapiens	3	0.7222
Disks large homolog 1	Q12959	DLG1_HUMAN	Homo sapiens	3	0.7222
Glycogen synthase kinase-3 beta	P49841	GSK3B_HUMAN	Homo sapiens	3	0.7221
Cytidine and deoxycytidylate deaminase zinc-binding region	Q82Y41	Q82Y41_NITEU	Nitrosomonas europaea	2	0.7221
Glycogen synthase kinase-3 beta	P49841	GSK3B_HUMAN	Homo sapiens	3	0.7221
Cytidine and deoxycytidylate deaminase zinc-binding region	Q82Y41	Q82Y41_NITEU	Nitrosomonas europaea	2	0.7221
Beta-galactoside-specific lectin 4	Q6ITZ3	ML4_VISAL	Viscum album	2	0.7220
Beta-galactoside-specific lectin 4	Q6ITZ3	ML4_VISAL	Viscum album	2	0.7220
Proto-oncogene tyrosine-protein kinase Src	P00523	SRC_CHICK	Gallus gallus	3	0.7220
Proto-oncogene tyrosine-protein kinase Src	P00523	SRC_CHICK	Gallus gallus	3	0.7220
Hygromycin-B 4-O-kinase	P00557	KHYB_ECOLX	Escherichia coli	3	0.7216
[LysW]-aminoadipate kinase	O50147	LYSZ_THET2	Thermus thermophilus	3	0.7216
Hygromycin-B 4-O-kinase	P00557	KHYB_ECOLX	Escherichia coli	3	0.7216
2',3'-cyclic-nucleotide 3'-phosphodiesterase	P16330	CN37_MOUSE	Mus musculus	2	0.7216
[LysW]-aminoadipate kinase	O50147	LYSZ_THET2	Thermus thermophilus	3	0.7216
2',3'-cyclic-nucleotide 3'-phosphodiesterase	P16330	CN37_MOUSE	Mus musculus	2	0.7216
L-lactate dehydrogenase A chain	P04642	LDHA_RAT	Rattus norvegicus	3	0.7215
L-lactate dehydrogenase A chain	P04642	LDHA_RAT	Rattus norvegicus	3	0.7215
Nuclear receptor subfamily 5 group A member 2	O00482	NR5A2_HUMAN	Homo sapiens	3	0.7213
Nuclear receptor subfamily 5 group A member 2	O00482	NR5A2_HUMAN	Homo sapiens	3	0.7213
Nickel-binding periplasmic protein	P33590	NIKA_ECOLI	Escherichia coli	2	0.7211
APH(2'')-Id	O68183	O68183_ENTCA	Enterococcus casseliflavus	3	0.7211
APH(2'')-Id	O68183	O68183_ENTCA	Enterococcus casseliflavus	3	0.7211
Tetracycline repressor protein class H	P51561	TETR8_PASMD	Pasteurella multocida	2	0.7211
Tetracycline repressor protein class H	P51561	TETR8_PASMD	Pasteurella multocida	2	0.7211
Nickel-binding periplasmic protein	P33590	NIKA_ECOLI	Escherichia coli	2	0.7211
Antitumor antibiotic C-1027 apoprotein	Q06110	CAGA_STRGL	Streptomyces globisporus	2	0.7207
Antitumor antibiotic C-1027 apoprotein	Q06110	CAGA_STRGL	Streptomyces globisporus	2	0.7207
Casein kinase II subunit alpha	P68400	CSK21_HUMAN	Homo sapiens	3	0.7207
Casein kinase II subunit alpha	P68400	CSK21_HUMAN	Homo sapiens	3	0.7207
Cyclic GMP-AMP phosphodiesterase SMPDL3A	Q92484	ASM3A_HUMAN	Homo sapiens	2	0.7202
Cyclic GMP-AMP phosphodiesterase SMPDL3A	Q92484	ASM3A_HUMAN	Homo sapiens	2	0.7202
Mitogen-activated protein kinase 14	Q16539	MK14_HUMAN	Homo sapiens	3	0.7201
Mitogen-activated protein kinase 14	Q16539	MK14_HUMAN	Homo sapiens	3	0.7201
Endoplasmin	P41148	ENPL_CANLF	Canis lupus familiaris	3	0.7200
Endoplasmin	P41148	ENPL_CANLF	Canis lupus familiaris	3	0.7200
ADP-ribosylation factor 1	P84077	ARF1_HUMAN	Homo sapiens	2	0.7199
ADP-ribosylation factor 1	P84077	ARF1_HUMAN	Homo sapiens	2	0.7199
Nitric oxide synthase, inducible	P29477	NOS2_MOUSE	Mus musculus	3	0.7194
Nitric oxide synthase, inducible	P29477	NOS2_MOUSE	Mus musculus	3	0.7194
Stromelysin-1	P08254	MMP3_HUMAN	Homo sapiens	2	0.7192
Stromelysin-1	P08254	MMP3_HUMAN	Homo sapiens	2	0.7192
Threonine--tRNA ligase	P0A8M3	SYT_ECOLI	Escherichia coli	3	0.7191
Threonine--tRNA ligase	P0A8M3	SYT_ECOLI	Escherichia coli	3	0.7191
DNA (cytosine-5)-methyltransferase 3A	O88508	DNM3A_MOUSE	Mus musculus	3	0.7186
DNA (cytosine-5)-methyltransferase 3A	O88508	DNM3A_MOUSE	Mus musculus	3	0.7186
Ras-related protein Rap-1b	P61224	RAP1B_HUMAN	Homo sapiens	3	0.7178
Ras-related protein Rap-1b	P61224	RAP1B_HUMAN	Homo sapiens	3	0.7178
Annexin A5	P08758	ANXA5_HUMAN	Homo sapiens	2	0.7177
Annexin A5	P08758	ANXA5_HUMAN	Homo sapiens	2	0.7177
eIF-2-alpha kinase GCN2	P15442	GCN2_YEAST	Saccharomyces cerevisiae	3	0.7174
eIF-2-alpha kinase GCN2	P15442	GCN2_YEAST	Saccharomyces cerevisiae	3	0.7174
N-terminal acetyltransferase A complex subunit NAT1	P12945	NAT1_YEAST	Saccharomyces cerevisiae	2	0.7173
N-terminal acetyltransferase A complex subunit NAT1	P12945	NAT1_YEAST	Saccharomyces cerevisiae	2	0.7173
Streptavidin	P22629	SAV_STRAV	Streptomyces avidinii	3	0.7173
Streptavidin	P22629	SAV_STRAV	Streptomyces avidinii	3	0.7173
Cytidine and deoxycytidylate deaminase zinc-binding region	Q82Y41	Q82Y41_NITEU	Nitrosomonas europaea	3	0.7171
Cytidine and deoxycytidylate deaminase zinc-binding region	Q82Y41	Q82Y41_NITEU	Nitrosomonas europaea	3	0.7171
Pantothenate synthetase	P9WIL5	PANC_MYCTU	Mycobacterium tuberculosis	5	0.7169
Pantothenate synthetase	P9WIL5	PANC_MYCTU	Mycobacterium tuberculosis	5	0.7169
Dihydropteroate synthase	Q81VW8	Q81VW8_BACAN	Bacillus anthracis	3	0.7169
Dihydropteroate synthase	Q81VW8	Q81VW8_BACAN	Bacillus anthracis	3	0.7169
Small heat shock protein StHsp14.0	Q970D9	Q970D9_SULTO	Sulfurisphaera tokodaii	3	0.7168
Small heat shock protein StHsp14.0	Q970D9	Q970D9_SULTO	Sulfurisphaera tokodaii	3	0.7168
1-deoxy-D-xylulose 5-phosphate reductoisomerase	P45568	DXR_ECOLI	Escherichia coli	2	0.7164
1-deoxy-D-xylulose 5-phosphate reductoisomerase	P45568	DXR_ECOLI	Escherichia coli	2	0.7164
Streptavidin	P22629	SAV_STRAV	Streptomyces avidinii	3	0.7164
Streptavidin	P22629	SAV_STRAV	Streptomyces avidinii	3	0.7164
Cyclin-dependent kinase 2	P24941	CDK2_HUMAN	Homo sapiens	3	0.7163
Cyclin-dependent kinase 2	P24941	CDK2_HUMAN	Homo sapiens	3	0.7163
Metallo-beta-lactamase type 2	C7C422	BLAN1_KLEPN	Klebsiella pneumoniae	2	0.7162
histone deacetylase	A5H660	A5H660_SCHMA	Schistosoma mansoni	3	0.7162
Interstitial collagenase	P03956	MMP1_HUMAN	Homo sapiens	3	0.7162
Metallo-beta-lactamase type 2	C7C422	BLAN1_KLEPN	Klebsiella pneumoniae	2	0.7162
histone deacetylase	A5H660	A5H660_SCHMA	Schistosoma mansoni	3	0.7162
Interstitial collagenase	P03956	MMP1_HUMAN	Homo sapiens	3	0.7162
Indole-3-glycerol phosphate synthase	P9WFX7	TRPC_MYCTU	Mycobacterium tuberculosis	2	0.7162
Indole-3-glycerol phosphate synthase	P9WFX7	TRPC_MYCTU	Mycobacterium tuberculosis	2	0.7162
Prothrombin	P00734	THRB_HUMAN	Homo sapiens	3	0.7160
Prothrombin	P00734	THRB_HUMAN	Homo sapiens	3	0.7160
Vitamin D-binding protein	P02774	VTDB_HUMAN	Homo sapiens	2	0.7158
HTH-type transcriptional repressor PurR	P0ACP7	PURR_ECOLI	Escherichia coli	2	0.7158
Vitamin D-binding protein	P02774	VTDB_HUMAN	Homo sapiens	2	0.7158
Histone-lysine N-methyltransferase EHMT1	Q9H9B1	EHMT1_HUMAN	Homo sapiens	3	0.7158
Histone-lysine N-methyltransferase EHMT1	Q9H9B1	EHMT1_HUMAN	Homo sapiens	3	0.7158
HTH-type transcriptional repressor PurR	P0ACP7	PURR_ECOLI	Escherichia coli	2	0.7158
Transitional endoplasmic reticulum ATPase	P55072	TERA_HUMAN	Homo sapiens	3	0.7156
Transitional endoplasmic reticulum ATPase	P55072	TERA_HUMAN	Homo sapiens	3	0.7156
Basic phospholipase A2 VRV-PL-VIIIa	P59071	PA2B8_DABRR	Daboia russelii	2	0.7155
Basic phospholipase A2 VRV-PL-VIIIa	P59071	PA2B8_DABRR	Daboia russelii	2	0.7155
N-alpha-acetyltransferase 50	Q9GZZ1	NAA50_HUMAN	Homo sapiens	3	0.7154
N-alpha-acetyltransferase 50	Q9GZZ1	NAA50_HUMAN	Homo sapiens	3	0.7154
Plasmid partition protein A	P07620	PARA_ECOLX	Escherichia coli	3	0.7154
Plasmid partition protein A	P07620	PARA_ECOLX	Escherichia coli	3	0.7154
Gag-Pol polyprotein	P03367	POL_HV1BR	Human immunodeficiency virus type 1 group M subtype B	3	0.7152
APH(2'')-Id	O68183	O68183_ENTCA	Enterococcus casseliflavus	3	0.7152
Gag-Pol polyprotein	P03367	POL_HV1BR	Human immunodeficiency virus type 1 group M subtype B	3	0.7152
APH(2'')-Id	O68183	O68183_ENTCA	Enterococcus casseliflavus	3	0.7152
Type II methyltransferase M.TaqI	P14385	MTTA_THEAQ	Thermus aquaticus	3	0.7149
Type II methyltransferase M.TaqI	P14385	MTTA_THEAQ	Thermus aquaticus	3	0.7149
Chaperone protein ClpB	Q9RA63	CLPB_THET8	Thermus thermophilus	3	0.7147
Methyltransferase	D0VX01	D0VX01_WSLV	Wesselsbron virus	3	0.7147
Chaperone protein ClpB	Q9RA63	CLPB_THET8	Thermus thermophilus	3	0.7147
Methyltransferase	D0VX01	D0VX01_WSLV	Wesselsbron virus	3	0.7147
Myosin heavy chain, striated muscle	P24733	MYS_ARGIR	Argopecten irradians	3	0.7146
Myosin heavy chain, striated muscle	P24733	MYS_ARGIR	Argopecten irradians	3	0.7146
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2	O88703	HCN2_MOUSE	Mus musculus	3	0.7141
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2	O88703	HCN2_MOUSE	Mus musculus	3	0.7141
Kinesin-like protein KIF11	P52732	KIF11_HUMAN	Homo sapiens	3	0.7140
Kinesin-like protein KIF11	P52732	KIF11_HUMAN	Homo sapiens	3	0.7140
Aldehyde dehydrogenase, mitochondrial	P05091	ALDH2_HUMAN	Homo sapiens	3	0.7139
Aldehyde dehydrogenase, mitochondrial	P05091	ALDH2_HUMAN	Homo sapiens	3	0.7139
Myosin heavy chain kinase A	P42527	MHCKA_DICDI	Dictyostelium discoideum	3	0.7134
Myosin heavy chain kinase A	P42527	MHCKA_DICDI	Dictyostelium discoideum	3	0.7134
Basic phospholipase A2 VRV-PL-VIIIa	P59071	PA2B8_DABRR	Daboia russelii	2	0.7132
Basic phospholipase A2 VRV-PL-VIIIa	P59071	PA2B8_DABRR	Daboia russelii	2	0.7132
4-hydroxy-7-methoxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl glucoside beta-D-glucosidase, chloroplastic	Q9FYS3	HGGL_SECCE	Secale cereale	3	0.7128
4-hydroxy-7-methoxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl glucoside beta-D-glucosidase, chloroplastic	Q9FYS3	HGGL_SECCE	Secale cereale	3	0.7128
Casein kinase II subunit alpha	P68400	CSK21_HUMAN	Homo sapiens	3	0.7127
Casein kinase II subunit alpha	P68400	CSK21_HUMAN	Homo sapiens	3	0.7127
UDP-galactopyranose mutase	Q48485	GLF1_KLEPN	Klebsiella pneumoniae	3	0.7126
UDP-galactopyranose mutase	Q48485	GLF1_KLEPN	Klebsiella pneumoniae	3	0.7126
Nitric oxide synthase, inducible	P29477	NOS2_MOUSE	Mus musculus	3	0.7125
ABC-type polar amino acid transport system, ATPase component	Q8RCC2	Q8RCC2_CALS4	Caldanaerobacter subterraneus subsp. tengcongensis	2	0.7125
Nitric oxide synthase, inducible	P29477	NOS2_MOUSE	Mus musculus	3	0.7125
ABC-type polar amino acid transport system, ATPase component	Q8RCC2	Q8RCC2_CALS4	Caldanaerobacter subterraneus subsp. tengcongensis	2	0.7125
Heat shock protein HSP 90-alpha	P07900	HS90A_HUMAN	Homo sapiens	3	0.7124
Heat shock protein HSP 90-alpha	P07900	HS90A_HUMAN	Homo sapiens	3	0.7124
Cyclic dipeptide N-prenyltransferase	D1D8L6	D1D8L6_ASPFM	Neosartorya fumigata	3	0.7123
Histone-lysine N-methyltransferase 2A	Q03164	KMT2A_HUMAN	Homo sapiens	3	0.7123
Histone-lysine N-methyltransferase 2A	Q03164	KMT2A_HUMAN	Homo sapiens	3	0.7123
Cyclic dipeptide N-prenyltransferase	D1D8L6	D1D8L6_ASPFM	Neosartorya fumigata	3	0.7123
Focal adhesion kinase 1	Q05397	FAK1_HUMAN	Homo sapiens	3	0.7119
Single-strand selective monofunctional uracil DNA glycosylase	Q9YGN6	SMUG1_XENLA	Xenopus laevis	3	0.7119
Focal adhesion kinase 1	Q05397	FAK1_HUMAN	Homo sapiens	3	0.7119
Single-strand selective monofunctional uracil DNA glycosylase	Q9YGN6	SMUG1_XENLA	Xenopus laevis	3	0.7119
Acyl-CoA dehydrogenase, short-chain specific	Q06319	ACDS_MEGEL	Megasphaera elsdenii	4	0.7117
Acyl-CoA dehydrogenase, short-chain specific	Q06319	ACDS_MEGEL	Megasphaera elsdenii	4	0.7117
Pantothenate synthetase	P9WIL5	PANC_MYCTU	Mycobacterium tuberculosis	4	0.7115
Gentisate 1,2-dioxygenase	Q67FT0	Q67FT0_PSESE	Pseudaminobacter salicylatoxidans	2	0.7115
Pantothenate synthetase	P9WIL5	PANC_MYCTU	Mycobacterium tuberculosis	4	0.7115
Gentisate 1,2-dioxygenase	Q67FT0	Q67FT0_PSESE	Pseudaminobacter salicylatoxidans	2	0.7115
Hygromycin-B 4-O-kinase	P00557	KHYB_ECOLX	Escherichia coli	3	0.7114
Hygromycin-B 4-O-kinase	P00557	KHYB_ECOLX	Escherichia coli	3	0.7114
rRNA N-glycosylase	D9J2T9	D9J2T9_MOMBA	Momordica balsamina	4	0.7113
rRNA N-glycosylase	D9J2T9	D9J2T9_MOMBA	Momordica balsamina	4	0.7113
Genome polyprotein	P12823	POLG_DEN2P	Dengue virus type 2	3	0.7112
Genome polyprotein	P12823	POLG_DEN2P	Dengue virus type 2	3	0.7112
Cyclin-dependent kinase 2	P24941	CDK2_HUMAN	Homo sapiens	3	0.7111
Cyclin-dependent kinase 2	P24941	CDK2_HUMAN	Homo sapiens	3	0.7111
Ribosomal protein S6 kinase alpha-1	Q15418	KS6A1_HUMAN	Homo sapiens	3	0.7110
Tryptase alpha/beta-1	Q15661	TRYB1_HUMAN	Homo sapiens	3	0.7110
Tryptase alpha/beta-1	Q15661	TRYB1_HUMAN	Homo sapiens	3	0.7110
Nitric oxide synthase oxygenase	O34453	NOSO_BACSU	Bacillus subtilis	3	0.7110
Ribosomal protein S6 kinase alpha-1	Q15418	KS6A1_HUMAN	Homo sapiens	3	0.7110
Nitric oxide synthase oxygenase	O34453	NOSO_BACSU	Bacillus subtilis	3	0.7110
Ribonuclease J	H9CZL7	H9CZL7_DEIRD	Deinococcus radiodurans	3	0.7109
Ribonuclease J	H9CZL7	H9CZL7_DEIRD	Deinococcus radiodurans	3	0.7109
3-phosphoinositide-dependent protein kinase 1	O15530	PDPK1_HUMAN	Homo sapiens	3	0.7108
3-phosphoinositide-dependent protein kinase 1	O15530	PDPK1_HUMAN	Homo sapiens	3	0.7108
Sulfide-quinone reductase	B7JBP8	SQRD_ACIF2	Acidithiobacillus ferrooxidans)	3	0.7106
Sulfide-quinone reductase	B7JBP8	SQRD_ACIF2	Acidithiobacillus ferrooxidans)	3	0.7106
Alpha-ketoglutarate-dependent dioxygenase FTO	Q9C0B1	FTO_HUMAN	Homo sapiens	2	0.7103
Alpha-ketoglutarate-dependent dioxygenase FTO	Q9C0B1	FTO_HUMAN	Homo sapiens	2	0.7103
2',3'-cyclic-nucleotide 3'-phosphodiesterase	P16330	CN37_MOUSE	Mus musculus	3	0.7103
2',3'-cyclic-nucleotide 3'-phosphodiesterase	P16330	CN37_MOUSE	Mus musculus	3	0.7103
Non-receptor tyrosine-protein kinase TYK2	P29597	TYK2_HUMAN	Homo sapiens	3	0.7102
Non-receptor tyrosine-protein kinase TYK2	P29597	TYK2_HUMAN	Homo sapiens	3	0.7102
Succinyl-CoA:acetate CoA-transferase	B3EY95	SCACT_ACEAC	Acetobacter aceti	2	0.7101
Succinyl-CoA:acetate CoA-transferase	B3EY95	SCACT_ACEAC	Acetobacter aceti	2	0.7101
dTDP-4-dehydrorhamnose 3,5-epimerase	A0A6L7H6N0	A0A1S0QLH9_BACAN	Bacillus anthracis	3	0.7100
dTDP-4-dehydrorhamnose 3,5-epimerase	A0A6L7H6N0	A0A1S0QLH9_BACAN	Bacillus anthracis	3	0.7100
Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase	Q9TQS6	DHDH_MACFA	Macaca fascicularis	2	0.7098
Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase	Q9TQS6	DHDH_MACFA	Macaca fascicularis	2	0.7098
5'-methylthioadenosine nucleosidase / s-adenosylhomocysteine nucleosidase	Q8YBL1	Q8YBL1_BRUME	Brucella melitensis biotype 1	3	0.7098
5'-methylthioadenosine nucleosidase / s-adenosylhomocysteine nucleosidase	Q8YBL1	Q8YBL1_BRUME	Brucella melitensis biotype 1	3	0.7098
Ephrin type-A receptor 2	P29317	EPHA2_HUMAN	Homo sapiens	3	0.7095
Thermolysin	P00800	THER_BACTH	Bacillus thermoproteolyticus	2	0.7095
Ephrin type-A receptor 2	P29317	EPHA2_HUMAN	Homo sapiens	3	0.7095
Thermolysin	P00800	THER_BACTH	Bacillus thermoproteolyticus	2	0.7095
Peroxisome proliferator-activated receptor gamma	P37231	PPARG_HUMAN	Homo sapiens	2	0.7093
Peroxisome proliferator-activated receptor gamma	P37231	PPARG_HUMAN	Homo sapiens	2	0.7093
Genome polyprotein	Q6YMS4	POLG_DEN3S	Dengue virus type 3	3	0.7092
Genome polyprotein	Q6YMS4	POLG_DEN3S	Dengue virus type 3	3	0.7092
DNA mismatch repair protein MutS	P23909	MUTS_ECOLI	Escherichia coli	3	0.7091
Stromelysin-1	P08254	MMP3_HUMAN	Homo sapiens	2	0.7091
DNA mismatch repair protein MutS	P23909	MUTS_ECOLI	Escherichia coli	3	0.7091
Stromelysin-1	P08254	MMP3_HUMAN	Homo sapiens	2	0.7091
Purine nucleoside phosphorylase	P00491	PNPH_HUMAN	Homo sapiens	3	0.7090
Single-stranded-DNA-specific exonuclease RecJ	D0EM60	D0EM60_DEIRD	Deinococcus radiodurans	2	0.7090
Purine nucleoside phosphorylase	P00491	PNPH_HUMAN	Homo sapiens	3	0.7090
Single-stranded-DNA-specific exonuclease RecJ	D0EM60	D0EM60_DEIRD	Deinococcus radiodurans	2	0.7090
Endoplasmin	P41148	ENPL_CANLF	Canis lupus familiaris	3	0.7089
Hypoxanthine-guanine phosphoribosyltransferase	P00492	HPRT_HUMAN	Homo sapiens	3	0.7089
Endoplasmin	P41148	ENPL_CANLF	Canis lupus familiaris	3	0.7089
Hypoxanthine-guanine phosphoribosyltransferase	P00492	HPRT_HUMAN	Homo sapiens	3	0.7089
Prothrombin	P00734	THRB_HUMAN	Homo sapiens	3	0.7087
Prothrombin	P00734	THRB_HUMAN	Homo sapiens	3	0.7087
Beta-adrenergic receptor kinase 1	P25098	ARBK1_HUMAN	Homo sapiens	3	0.7086
Beta-adrenergic receptor kinase 1	P25098	ARBK1_HUMAN	Homo sapiens	3	0.7086
Cyclin-dependent kinase 9	P50750	CDK9_HUMAN	Homo sapiens	3	0.7084
Cyclin-dependent kinase 9	P50750	CDK9_HUMAN	Homo sapiens	3	0.7084
Serine/threonine-protein kinase PLK	Q4KMI8	Q4KMI8_DANRE	Danio rerio	3	0.7083
Serine/threonine-protein kinase PLK	Q4KMI8	Q4KMI8_DANRE	Danio rerio	3	0.7083
Histone-lysine N-methyltransferase EHMT1	Q9H9B1	EHMT1_HUMAN	Homo sapiens	3	0.7077
Adenylate cyclase type 5	P30803	ADCY5_CANLF	Canis lupus familiaris	3	0.7077
Adenylate cyclase type 5	P30803	ADCY5_CANLF	Canis lupus familiaris	3	0.7077
Histone-lysine N-methyltransferase EHMT1	Q9H9B1	EHMT1_HUMAN	Homo sapiens	3	0.7077
Peripheral plasma membrane protein CASK	O14936	CSKP_HUMAN	Homo sapiens	3	0.7075
Peripheral plasma membrane protein CASK	O14936	CSKP_HUMAN	Homo sapiens	3	0.7075
Purine nucleoside phosphorylase DeoD-type	P0ABP8	DEOD_ECOLI	Escherichia coli	3	0.7069
Purine nucleoside phosphorylase DeoD-type	P0ABP8	DEOD_ECOLI	Escherichia coli	3	0.7069
Pteridine reductase	O76290	O76290_TRYBB	Trypanosoma brucei brucei	3	0.7068
Pteridine reductase	O76290	O76290_TRYBB	Trypanosoma brucei brucei	3	0.7068
Dihydrofolate reductase	P0ABQ4	DYR_ECOLI	Escherichia coli	4	0.7065
Dihydrofolate reductase	P0ABQ4	DYR_ECOLI	Escherichia coli	4	0.7065
Bis(5'-adenosyl)-triphosphatase	P49789	FHIT_HUMAN	Homo sapiens	2	0.7064
Bis(5'-adenosyl)-triphosphatase	P49789	FHIT_HUMAN	Homo sapiens	2	0.7064
Uridine phosphorylase	P0A1F6	UDP_SALTY	Salmonella typhimurium	3	0.7061
Uridine phosphorylase	P0A1F6	UDP_SALTY	Salmonella typhimurium	3	0.7061
Hypoxanthine-guanine phosphoribosyltransferase	P00492	HPRT_HUMAN	Homo sapiens	3	0.7060
Hypoxanthine-guanine phosphoribosyltransferase	P00492	HPRT_HUMAN	Homo sapiens	3	0.7060
Thermolysin	P00800	THER_BACTH	Bacillus thermoproteolyticus	3	0.7058
Thermolysin	P00800	THER_BACTH	Bacillus thermoproteolyticus	3	0.7058
Polyribonucleotide nucleotidyltransferase	A7ZS61	PNP_ECO24	Escherichia coli O139:H28	3	0.7057
Polyribonucleotide nucleotidyltransferase	A7ZS61	PNP_ECO24	Escherichia coli O139:H28	3	0.7057
Holliday junction branch migration complex subunit RuvB	Q9PMT7	RUVB_CAMJE	Campylobacter jejuni subsp. jejuni serotype O:2	2	0.7056
Holliday junction branch migration complex subunit RuvB	Q9PMT7	RUVB_CAMJE	Campylobacter jejuni subsp. jejuni serotype O:2	2	0.7056
Poly [ADP-ribose] polymerase 1	P09874	PARP1_HUMAN	Homo sapiens	3	0.7056
Poly [ADP-ribose] polymerase 1	P09874	PARP1_HUMAN	Homo sapiens	3	0.7056
Tau-tubulin kinase 1	Q5TCY1	TTBK1_HUMAN	Homo sapiens	3	0.7055
Tau-tubulin kinase 1	Q5TCY1	TTBK1_HUMAN	Homo sapiens	3	0.7055
Serine/threonine-protein kinase Chk1	O14757	CHK1_HUMAN	Homo sapiens	3	0.7054
Serine/threonine-protein kinase Chk1	O14757	CHK1_HUMAN	Homo sapiens	3	0.7054
Dihydroorotate dehydrogenase (quinone), mitochondrial	Q08210	PYRD_PLAF7	Plasmodium falciparum	3	0.7053
Dihydroorotate dehydrogenase (quinone), mitochondrial	Q08210	PYRD_PLAF7	Plasmodium falciparum	3	0.7053
Adenine DNA glycosylase	P83847	MUTY_GEOSE	Geobacillus stearothermophilus	3	0.7053
Adenine DNA glycosylase	P83847	MUTY_GEOSE	Geobacillus stearothermophilus	3	0.7053
Type II methyltransferase M.TaqI	P14385	MTTA_THEAQ	Thermus aquaticus	3	0.7052
Type II methyltransferase M.TaqI	P14385	MTTA_THEAQ	Thermus aquaticus	3	0.7052
Acetolactate synthase, chloroplastic	P17597	ILVB_ARATH	Arabidopsis thaliana	2	0.7048
Acetolactate synthase, chloroplastic	P17597	ILVB_ARATH	Arabidopsis thaliana	2	0.7048
Rhodopsin kinase GRK1	P28327	GRK1_BOVIN	Bos taurus	3	0.7047
Rhodopsin kinase GRK1	P28327	GRK1_BOVIN	Bos taurus	3	0.7047
Aspartate carbamoyltransferase catalytic subunit	P0A786	PYRB_ECOLI	Escherichia coli	3	0.7046
Protocatechuate 3,4-dioxygenase beta chain	P00437	PCXB_PSEPU	Pseudomonas putida	2	0.7046
Aspartate carbamoyltransferase catalytic subunit	P0A786	PYRB_ECOLI	Escherichia coli	3	0.7046
Protocatechuate 3,4-dioxygenase beta chain	P00437	PCXB_PSEPU	Pseudomonas putida	2	0.7046
Fibroblast growth factor receptor 2	P21802	FGFR2_HUMAN	Homo sapiens	3	0.7034
Fibroblast growth factor receptor 2	P21802	FGFR2_HUMAN	Homo sapiens	3	0.7034
Purine nucleoside phosphorylase	P00491	PNPH_HUMAN	Homo sapiens	3	0.7032
Purine nucleoside phosphorylase	P00491	PNPH_HUMAN	Homo sapiens	3	0.7032
Carbonic anhydrase 2	P00918	CAH2_HUMAN	Homo sapiens	2	0.7030
Carbonic anhydrase 2	P00918	CAH2_HUMAN	Homo sapiens	2	0.7030
Collagenase 3	P45452	MMP13_HUMAN	Homo sapiens	3	0.7029
Collagenase 3	P45452	MMP13_HUMAN	Homo sapiens	3	0.7029
Alpha-ketoglutarate-dependent dioxygenase FTO	Q9C0B1	FTO_HUMAN	Homo sapiens	2	0.7028
Alpha-ketoglutarate-dependent dioxygenase FTO	Q9C0B1	FTO_HUMAN	Homo sapiens	2	0.7028
Queuine tRNA-ribosyltransferase	P28720	TGT_ZYMMO	Zymomonas mobilis subsp. mobilis	2	0.7026
Queuine tRNA-ribosyltransferase	P28720	TGT_ZYMMO	Zymomonas mobilis subsp. mobilis	2	0.7026
Anthranilate phosphoribosyltransferase	P00500	TRPD_ACIAD	Acinetobacter baylyi	2	0.7025
Anthranilate phosphoribosyltransferase	P00500	TRPD_ACIAD	Acinetobacter baylyi	2	0.7025
Tyrosine-protein kinase SYK	P43405	KSYK_HUMAN	Homo sapiens	3	0.7024
Gag-Pol polyprotein	P12497	POL_HV1N5	Human immunodeficiency virus type 1 group M subtype B	2	0.7024
Gag-Pol polyprotein	P12497	POL_HV1N5	Human immunodeficiency virus type 1 group M subtype B	2	0.7024
Tyrosine-protein kinase SYK	P43405	KSYK_HUMAN	Homo sapiens	3	0.7024
Tyrosine-protein kinase JAK1	P23458	JAK1_HUMAN	Homo sapiens	3	0.7023
Tyrosine-protein kinase JAK1	P23458	JAK1_HUMAN	Homo sapiens	3	0.7023
Histone-lysine N-methyltransferase KMT5C	Q6Q783	KMT5C_MOUSE	Mus musculus	4	0.7022
Histone-lysine N-methyltransferase KMT5C	Q6Q783	KMT5C_MOUSE	Mus musculus	4	0.7022
Prothrombin	P00734	THRB_HUMAN	Homo sapiens	2	0.7021
Prothrombin	P00734	THRB_HUMAN	Homo sapiens	2	0.7021
Queuine tRNA-ribosyltransferase	P28720	TGT_ZYMMO	Zymomonas mobilis subsp. mobilis	2	0.7020
Queuine tRNA-ribosyltransferase	P28720	TGT_ZYMMO	Zymomonas mobilis subsp. mobilis	2	0.7020
Thymidine kinase	P0DTH5	KITH_HHV11	Human herpesvirus 1	2	0.7019
Thymidine kinase	P0DTH5	KITH_HHV11	Human herpesvirus 1	2	0.7019
Glycogen synthase kinase-3 beta	P49841	GSK3B_HUMAN	Homo sapiens	3	0.7017
Glycogen synthase kinase-3 beta	P49841	GSK3B_HUMAN	Homo sapiens	3	0.7017
Aspartate aminotransferase	P00509	AAT_ECOLI	Escherichia coli	2	0.7015
Aspartate aminotransferase	P00509	AAT_ECOLI	Escherichia coli	2	0.7015
Biotin carboxylase	P43873	ACCC_HAEIN	Haemophilus influenzae	3	0.7013
Biotin carboxylase	P43873	ACCC_HAEIN	Haemophilus influenzae	3	0.7013
Mitochondrial poly(A) polymerase	F1NBW0	F1NBW0_CHICK	Gallus gallus	2	0.7012
Transitional endoplasmic reticulum ATPase	P55072	TERA_HUMAN	Homo sapiens	3	0.7012
Transitional endoplasmic reticulum ATPase	P55072	TERA_HUMAN	Homo sapiens	3	0.7012
Mitochondrial poly(A) polymerase	F1NBW0	F1NBW0_CHICK	Gallus gallus	2	0.7012
Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase	Q05603	COBT_SALTY	Salmonella typhimurium	3	0.7011
Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase	Q05603	COBT_SALTY	Salmonella typhimurium	3	0.7011
Serine/threonine-protein kinase Chk1	O14757	CHK1_HUMAN	Homo sapiens	3	0.7007
Tyrosine-protein kinase JAK3	P52333	JAK3_HUMAN	Homo sapiens	3	0.7007
Serine/threonine-protein kinase Chk1	O14757	CHK1_HUMAN	Homo sapiens	3	0.7007
Tyrosine-protein kinase JAK3	P52333	JAK3_HUMAN	Homo sapiens	3	0.7007
Ribonuclease 4	P15468	RNAS4_PIG	Sus scrofa	2	0.7005
Ribonuclease 4	P15468	RNAS4_PIG	Sus scrofa	2	0.7005
Phospholipase A2, major isoenzyme	P00592	PA21B_PIG	Sus scrofa	2	0.7004
Gag-Pol polyprotein	P05896	POL_SIVM1	Simian immunodeficiency virus	3	0.7004
Bifunctional protein GAL10	P04397	GAL10_YEAST	Saccharomyces cerevisiae	4	0.7004
Bifunctional protein GAL10	P04397	GAL10_YEAST	Saccharomyces cerevisiae	4	0.7004
Gag-Pol polyprotein	P05896	POL_SIVM1	Simian immunodeficiency virus	3	0.7004
Phospholipase A2, major isoenzyme	P00592	PA21B_PIG	Sus scrofa	2	0.7004
Queuine tRNA-ribosyltransferase	P28720	TGT_ZYMMO	Zymomonas mobilis subsp. mobilis	3	0.7003
Queuine tRNA-ribosyltransferase	P28720	TGT_ZYMMO	Zymomonas mobilis subsp. mobilis	3	0.7003
DNA-binding transcriptional dual regulator CRP	P0ACJ8	CRP_ECOLI	Escherichia coli	4	0.7002
DNA-binding transcriptional dual regulator CRP	P0ACJ8	CRP_ECOLI	Escherichia coli	4	0.7002

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