Casticin - Compound Card

Casticin

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Casticin

Structure
Zoomed Structure
  • Family: Plantae - Asteraceae
  • Kingdom: Plantae
  • Class: Flavonoid
    • Subclass: Flavonol Aglycone
Canonical Smiles COc1cc2oc(c3ccc(c(c3)O)OC)c(c(=O)c2c(c1OC)O)OC
InChI InChI=1S/C19H18O8/c1-23-11-6-5-9(7-10(11)20)17-19(26-4)16(22)14-12(27-17)8-13(24-2)18(25-3)15(14)21/h5-8,20-21H,1-4H3
InChIKey PJQLSMYMOKWUJG-UHFFFAOYSA-N
Formula C19H18O8
HBA 8
HBD 2
MW 374.35
Rotatable Bonds 5
TPSA 107.59
LogP 2.91
Number Rings 3
Number Aromatic Rings 3
Heavy Atom Count 27
Formal Charge 0
Fraction CSP3 0.21
Exact Mass 374.1
Number of Lipinski Rule Violations 0
# Species Family Kingdom NCBI Taxonomy ID
1 Artemisia judaica Asteraceae Plantae 205369
2 Jasonia montana Asteraceae Plantae 441235

Showing of synonyms

  • Ahmed AA, Ali AA, et al. (1989). Flavonoids aglycones from Jasonia montana. Phytochemistry,1989,28(2),665-667. [View]
  • Saleh NAM, El-Negoumy SI, et al. (1987). Flavonoids of Artemisia judaica, A. monosperma and A. Herba-alba.. Phytochemistry,1987,26(11),3059-3064. [View]
Pubchem: 5315263
Chebi: 69355
Nmrshiftdb2: 60022758
Metabolights: MTBLC69355
CPRiL: 57167
Structure

SMILES: c1cccc(c12)oc(cc2=O)-c3ccccc3

Level: 1

Mol. Weight: 374.35 g/mol

Structure

SMILES: c1cccc(c12)occc2=O

Level: 0

Mol. Weight: 374.35 g/mol

Structure

SMILES: c1ccccc1

Level: 0

Mol. Weight: 374.35 g/mol

No bioactivities available.

Absorption

Caco-2 (logPapp)
-4.71
Human Oral Bioavailability 20%
Bioavailable
Human Intestinal Absorption
Absorbed
Madin-Darby Canine Kidney
-4.910
Human Oral Bioavailability 50%
Bioavailable
P-Glycoprotein Inhibitor
Inhibitor
P-Glycoprotein Substrate
Non-Substrate
Skin Permeability
-0.97

Distribution

Blood-Brain Barrier (CNS)
-
Blood-Brain Barrier
Non-Penetrable
Fraction Unbound (Human)
1.360
Plasma Protein Binding
76.88
Steady State Volume of Distribution
-

Metabolism

Breast Cancer Resistance Protein
Inhibitor
CYP 1A2 Inhibitor
Inhibitor
CYP 1A2 Substrate
Substrate
CYP 2C19 Inhibitor
Inhibitor
CYP 2C19 Substrate
Non-Substrate
CYP 2C9 Inhibitor
Inhibitor
CYP 2C9 Substrate
Substrate
CYP 2D6 Inhibitor
Non-Inhibitor
CYP 2D6 Substrate
Non-Substrate
CYP 3A4 Inhibitor
Non-Inhibitor
CYP 3A4 Substrate
Non-Substrate
OATP1B1
Non-Inhibitor
OATP1B3
Non-Inhibitor

Excretion

Clearance
8.490
Organic Cation Transporter 2
Non-Inhibitor
Half-Life of Drug
-

Toxicity

AMES Mutagenesis
Safe
Avian
Safe
Bee
Toxic
Bioconcentration Factor
1.970
Biodegradation
Safe
Carcinogenesis
Safe
Crustacean
Toxic
Liver Injury I (DILI)
Toxic
Eye Corrosion
Safe
Eye Irritation
Toxic
Maximum Tolerated Dose
1.600
Liver Injury II
Toxic
hERG Blockers
Safe
Daphnia Maga
7.370
Micronucleos
Toxic
NR-AhR
Toxic
NR-AR
Safe
NR-AR-LBD
Safe
NR-Aromatase
Safe
NR-ER
Safe
NR-ER-LBD
Safe
NR-GR
Safe
NR-PPAR-gamma
Safe
NR-TR
Safe
T. Pyriformis
-1.830
Rat (Acute)
2.230
Rat (Chronic Oral)
2.770
Fathead Minnow
4.970
Respiratory Disease
Toxic
Skin Sensitisation
Safe
SR-ARE
Toxic
SR-ATAD5
Toxic
SR-HSE
Safe
SR-MMP
Toxic
SR-p53
Toxic

General Properties

Boiling Point
470.900
Hydration Free Energy
-8.970
Log(D) at pH=7.4
3.200
Log(P)
2.74
Log S
-4.78
Log(Vapor Pressure)
-7.51
Melting Point
175.39
pKa Acid
7.37
pKa Basic
2.07
Protein Name UniProt ID Entry Name Species #Pharmacophore Points Probability (0.7 ≤ Tversky Score ≤ 1.0)
Chitinase A Q9AMP1 Q9AMP1_VIBHA Vibrio harveyi 3 0.9765
Chitinase A Q9AMP1 Q9AMP1_VIBHA Vibrio harveyi 3 0.9765
Cathepsin S P25774 CATS_HUMAN Homo sapiens 3 0.9541
Cathepsin S P25774 CATS_HUMAN Homo sapiens 3 0.9541
HTH-type transcriptional regulator TtgR Q9AIU0 TTGR_PSEPT Pseudomonas putida 3 0.9447
HTH-type transcriptional regulator TtgR Q9AIU0 TTGR_PSEPT Pseudomonas putida 3 0.9447
3',5'-cyclic-AMP phosphodiesterase 4D Q08499 PDE4D_HUMAN Homo sapiens 3 0.9429
3',5'-cyclic-AMP phosphodiesterase 4D Q08499 PDE4D_HUMAN Homo sapiens 3 0.9429
Heat shock protein HSP 90-alpha P07900 HS90A_HUMAN Homo sapiens 3 0.9404
Heat shock protein HSP 90-alpha P07900 HS90A_HUMAN Homo sapiens 3 0.9404
HTH-type transcriptional regulator TtgR Q9AIU0 TTGR_PSEPT Pseudomonas putida 4 0.9355
HTH-type transcriptional regulator TtgR Q9AIU0 TTGR_PSEPT Pseudomonas putida 4 0.9355
Basic phospholipase A2 VRV-PL-VIIIa P59071 PA2B8_DABRR Daboia russelii 3 0.9301
Basic phospholipase A2 VRV-PL-VIIIa P59071 PA2B8_DABRR Daboia russelii 3 0.9301
Bromodomain adjacent to zinc finger domain protein 2B Q9UIF8 BAZ2B_HUMAN Homo sapiens 3 0.9236
Bromodomain adjacent to zinc finger domain protein 2B Q9UIF8 BAZ2B_HUMAN Homo sapiens 3 0.9236
rRNA N-glycosylase D9J2T9 D9J2T9_MOMBA Momordica balsamina 3 0.9193
rRNA N-glycosylase D9J2T9 D9J2T9_MOMBA Momordica balsamina 3 0.9193
ATP synthase subunit alpha, mitochondrial P19483 ATPA_BOVIN Bos taurus 3 0.9138
ATP synthase subunit alpha, mitochondrial P19483 ATPA_BOVIN Bos taurus 3 0.9138
Death-associated protein kinase 1 P53355 DAPK1_HUMAN Homo sapiens 4 0.9066
Death-associated protein kinase 1 P53355 DAPK1_HUMAN Homo sapiens 4 0.9066
Tetracycline repressor protein class H P51561 TETR8_PASMD Pasteurella multocida 3 0.9049
Tetracycline repressor protein class H P51561 TETR8_PASMD Pasteurella multocida 3 0.9049
Stromelysin-1 P08254 MMP3_HUMAN Homo sapiens 3 0.9043
Stromelysin-1 P08254 MMP3_HUMAN Homo sapiens 3 0.9043
Poly [ADP-ribose] polymerase tankyrase-2 Q9H2K2 TNKS2_HUMAN Homo sapiens 4 0.8947
Poly [ADP-ribose] polymerase tankyrase-2 Q9H2K2 TNKS2_HUMAN Homo sapiens 4 0.8947
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A Q9Y233 PDE10_HUMAN Homo sapiens 3 0.8930
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A Q9Y233 PDE10_HUMAN Homo sapiens 3 0.8930
NAD(P)H-hydrate epimerase Q8K4Z3 NNRE_MOUSE Mus musculus 3 0.8874
NAD(P)H-hydrate epimerase Q8K4Z3 NNRE_MOUSE Mus musculus 3 0.8874
Tyrosine-protein kinase Lck P06239 LCK_HUMAN Homo sapiens 4 0.8865
Tyrosine-protein kinase Lck P06239 LCK_HUMAN Homo sapiens 4 0.8865
histidine kinase O32393 O32393_ARTPT Arthrospira platensis 3 0.8858
HTH-type transcriptional repressor PurR P0ACP7 PURR_ECOLI Escherichia coli 3 0.8858
histidine kinase O32393 O32393_ARTPT Arthrospira platensis 3 0.8858
HTH-type transcriptional repressor PurR P0ACP7 PURR_ECOLI Escherichia coli 3 0.8858
Carbonic anhydrase 2 P00918 CAH2_HUMAN Homo sapiens 3 0.8820
Carbonic anhydrase 2 P00918 CAH2_HUMAN Homo sapiens 3 0.8820
MAP kinase-activated protein kinase 2 P49137 MAPK2_HUMAN Homo sapiens 3 0.8819
MAP kinase-activated protein kinase 2 P49137 MAPK2_HUMAN Homo sapiens 3 0.8819
Poly [ADP-ribose] polymerase tankyrase-2 Q9H2K2 TNKS2_HUMAN Homo sapiens 5 0.8804
Poly [ADP-ribose] polymerase tankyrase-2 Q9H2K2 TNKS2_HUMAN Homo sapiens 5 0.8804
Uracil phosphoribosyltransferase Q26998 UPP_TOXGO Toxoplasma gondii 3 0.8782
Uracil phosphoribosyltransferase Q26998 UPP_TOXGO Toxoplasma gondii 3 0.8782
Poly [ADP-ribose] polymerase tankyrase-2 Q9H2K2 TNKS2_HUMAN Homo sapiens 4 0.8763
Poly [ADP-ribose] polymerase tankyrase-2 Q9H2K2 TNKS2_HUMAN Homo sapiens 4 0.8763
Tetracycline repressor protein class D P0ACT4 TETR4_ECOLX Escherichia coli 3 0.8732
Tetracycline repressor protein class D P0ACT4 TETR4_ECOLX Escherichia coli 3 0.8732
Capsid protein Q9WBP8 Q9WBP8_9VIRU Adeno-associated virus - 1 3 0.8716
Capsid protein Q9WBP8 Q9WBP8_9VIRU Adeno-associated virus - 1 3 0.8716
Poly [ADP-ribose] polymerase tankyrase-2 Q9H2K2 TNKS2_HUMAN Homo sapiens 4 0.8712
Poly [ADP-ribose] polymerase tankyrase-2 Q9H2K2 TNKS2_HUMAN Homo sapiens 4 0.8712
Cathepsin S P25774 CATS_HUMAN Homo sapiens 3 0.8698
Cathepsin S P25774 CATS_HUMAN Homo sapiens 3 0.8698
Poly [ADP-ribose] polymerase tankyrase-2 Q9H2K2 TNKS2_HUMAN Homo sapiens 4 0.8690
Poly [ADP-ribose] polymerase tankyrase-2 Q9H2K2 TNKS2_HUMAN Homo sapiens 4 0.8690
Uracil phosphoribosyltransferase Q26998 UPP_TOXGO Toxoplasma gondii 3 0.8681
Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase Q9TQS6 DHDH_MACFA Macaca fascicularis 3 0.8681
Uracil phosphoribosyltransferase Q26998 UPP_TOXGO Toxoplasma gondii 3 0.8681
Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase Q9TQS6 DHDH_MACFA Macaca fascicularis 3 0.8681
Cytochrome P450 1A1 P04798 CP1A1_HUMAN Homo sapiens 3 0.8663
Cytochrome P450 1A1 P04798 CP1A1_HUMAN Homo sapiens 3 0.8663
Dihydroflavonol 4-reductase P51110 DFRA_VITVI Vitis vinifera 4 0.8565
Dihydroflavonol 4-reductase P51110 DFRA_VITVI Vitis vinifera 4 0.8565
Death-associated protein kinase 1 P53355 DAPK1_HUMAN Homo sapiens 6 0.8542
Death-associated protein kinase 1 P53355 DAPK1_HUMAN Homo sapiens 6 0.8542
Dihydroflavonol 4-reductase P51110 DFRA_VITVI Vitis vinifera 4 0.8535
Dihydroflavonol 4-reductase P51110 DFRA_VITVI Vitis vinifera 4 0.8535
Endoplasmin P41148 ENPL_CANLF Canis lupus familiaris 4 0.8525
Endoplasmin P41148 ENPL_CANLF Canis lupus familiaris 4 0.8525
Flavin-dependent monooxygenase Q93L51 TETX_BACT4 Bacteroides thetaiotaomicron 3 0.8521
Flavin-dependent monooxygenase Q93L51 TETX_BACT4 Bacteroides thetaiotaomicron 3 0.8521
Poly [ADP-ribose] polymerase tankyrase-2 Q9H2K2 TNKS2_HUMAN Homo sapiens 4 0.8518
Poly [ADP-ribose] polymerase tankyrase-2 Q9H2K2 TNKS2_HUMAN Homo sapiens 4 0.8518
Cyclic dipeptide N-prenyltransferase D1D8L6 D1D8L6_ASPFM Neosartorya fumigata 3 0.8513
Cyclic dipeptide N-prenyltransferase D1D8L6 D1D8L6_ASPFM Neosartorya fumigata 3 0.8513
Epidermal growth factor receptor P00533 EGFR_HUMAN Homo sapiens 3 0.8512
Epidermal growth factor receptor P00533 EGFR_HUMAN Homo sapiens 3 0.8512
Poly [ADP-ribose] polymerase tankyrase-2 Q9H2K2 TNKS2_HUMAN Homo sapiens 4 0.8504
Poly [ADP-ribose] polymerase tankyrase-2 Q9H2K2 TNKS2_HUMAN Homo sapiens 4 0.8504
Poly [ADP-ribose] polymerase tankyrase-2 Q9H2K2 TNKS2_HUMAN Homo sapiens 5 0.8450
Poly [ADP-ribose] polymerase tankyrase-2 Q9H2K2 TNKS2_HUMAN Homo sapiens 5 0.8450
Epidermal growth factor receptor P00533 EGFR_HUMAN Homo sapiens 3 0.8438
Epidermal growth factor receptor P00533 EGFR_HUMAN Homo sapiens 3 0.8438
Poly [ADP-ribose] polymerase tankyrase-2 Q9H2K2 TNKS2_HUMAN Homo sapiens 4 0.8405
Poly [ADP-ribose] polymerase tankyrase-2 Q9H2K2 TNKS2_HUMAN Homo sapiens 4 0.8405
Phosphatidylinositol 5-phosphate 4-kinase type-2 beta P78356 PI42B_HUMAN Homo sapiens 4 0.8399
Phosphatidylinositol 5-phosphate 4-kinase type-2 beta P78356 PI42B_HUMAN Homo sapiens 4 0.8399
Steroid Delta-isomerase P00947 SDIS_COMTE Comamonas testosteroni 3 0.8376
Steroid Delta-isomerase P00947 SDIS_COMTE Comamonas testosteroni 3 0.8376
Anthocyanidin 3-O-glucosyltransferase UFGT P51094 UFOG_VITVI Vitis vinifera 4 0.8364
Anthocyanidin 3-O-glucosyltransferase UFGT P51094 UFOG_VITVI Vitis vinifera 4 0.8364
Poly [ADP-ribose] polymerase tankyrase-2 Q9H2K2 TNKS2_HUMAN Homo sapiens 4 0.8353
Poly [ADP-ribose] polymerase tankyrase-2 Q9H2K2 TNKS2_HUMAN Homo sapiens 4 0.8353
Carbonyl reductase [NADPH] 1 P16152 CBR1_HUMAN Homo sapiens 3 0.8325
Carbonyl reductase [NADPH] 1 P16152 CBR1_HUMAN Homo sapiens 3 0.8325
Rhodopsin kinase GRK1 P28327 GRK1_BOVIN Bos taurus 3 0.8321
Rhodopsin kinase GRK1 P28327 GRK1_BOVIN Bos taurus 3 0.8321
Serine/threonine-protein kinase 24 Q9Y6E0 STK24_HUMAN Homo sapiens 3 0.8296
Serine/threonine-protein kinase 24 Q9Y6E0 STK24_HUMAN Homo sapiens 3 0.8296
Poly [ADP-ribose] polymerase tankyrase-2 Q9H2K2 TNKS2_HUMAN Homo sapiens 4 0.8293
Poly [ADP-ribose] polymerase tankyrase-2 Q9H2K2 TNKS2_HUMAN Homo sapiens 4 0.8293
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform P48736 PK3CG_HUMAN Homo sapiens 4 0.8286
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform P48736 PK3CG_HUMAN Homo sapiens 4 0.8286
Protein mono-ADP-ribosyltransferase PARP3 Q9Y6F1 PARP3_HUMAN Homo sapiens 3 0.8275
Protein mono-ADP-ribosyltransferase PARP3 Q9Y6F1 PARP3_HUMAN Homo sapiens 3 0.8275
Homoserine dehydrogenase P31116 DHOM_YEAST Saccharomyces cerevisiae 4 0.8253
Homoserine dehydrogenase P31116 DHOM_YEAST Saccharomyces cerevisiae 4 0.8253
Cytosine-specific methyltransferase Q8EVR5 Q8EVR5_MYCPE Mycoplasma penetrans 4 0.8244
Cytosine-specific methyltransferase Q8EVR5 Q8EVR5_MYCPE Mycoplasma penetrans 4 0.8244
Carbonic anhydrase 2 P00918 CAH2_HUMAN Homo sapiens 3 0.8233
Carbonic anhydrase 2 P00918 CAH2_HUMAN Homo sapiens 3 0.8233
ATP-dependent molecular chaperone HSP82 P02829 HSP82_YEAST Saccharomyces cerevisiae 3 0.8224
ATP-dependent molecular chaperone HSP82 P02829 HSP82_YEAST Saccharomyces cerevisiae 3 0.8224
Serine/threonine-protein kinase 10 O94804 STK10_HUMAN Homo sapiens 3 0.8208
Serine/threonine-protein kinase 10 O94804 STK10_HUMAN Homo sapiens 3 0.8208
Poly [ADP-ribose] polymerase tankyrase-2 Q9H2K2 TNKS2_HUMAN Homo sapiens 4 0.8177
Chitinase A Q9AMP1 Q9AMP1_VIBHA Vibrio harveyi 3 0.8177
Chitinase A Q9AMP1 Q9AMP1_VIBHA Vibrio harveyi 3 0.8177
Poly [ADP-ribose] polymerase tankyrase-2 Q9H2K2 TNKS2_HUMAN Homo sapiens 4 0.8177
APH(2'')-Id O68183 O68183_ENTCA Enterococcus casseliflavus 4 0.8153
APH(2'')-Id O68183 O68183_ENTCA Enterococcus casseliflavus 4 0.8153
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform O02697 PK3CG_PIG Sus scrofa 4 0.8103
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform O02697 PK3CG_PIG Sus scrofa 4 0.8103
Type II methyltransferase M.TaqI P14385 MTTA_THEAQ Thermus aquaticus 4 0.8100
Type II methyltransferase M.TaqI P14385 MTTA_THEAQ Thermus aquaticus 4 0.8100
ATP-dependent molecular chaperone HSP82 P02829 HSP82_YEAST Saccharomyces cerevisiae 3 0.8093
ATP-dependent molecular chaperone HSP82 P02829 HSP82_YEAST Saccharomyces cerevisiae 3 0.8093
Death-associated protein kinase 1 P53355 DAPK1_HUMAN Homo sapiens 5 0.8092
Death-associated protein kinase 1 P53355 DAPK1_HUMAN Homo sapiens 5 0.8092
Ribosyldihydronicotinamide dehydrogenase [quinone] P16083 NQO2_HUMAN Homo sapiens 4 0.8040
Ribosyldihydronicotinamide dehydrogenase [quinone] P16083 NQO2_HUMAN Homo sapiens 4 0.8040
Serine/threonine-protein kinase SKY1 Q03656 SKY1_YEAST Saccharomyces cerevisiae 3 0.8033
Serine/threonine-protein kinase SKY1 Q03656 SKY1_YEAST Saccharomyces cerevisiae 3 0.8033
Poly [ADP-ribose] polymerase tankyrase-2 Q9H2K2 TNKS2_HUMAN Homo sapiens 5 0.8025
Poly [ADP-ribose] polymerase tankyrase-2 Q9H2K2 TNKS2_HUMAN Homo sapiens 5 0.8025
Phytohormone-binding protein CSBP A0A1S3THR8 PHBP_VIGRR Vigna radiata var. radiata 3 0.8021
Phytohormone-binding protein CSBP A0A1S3THR8 PHBP_VIGRR Vigna radiata var. radiata 3 0.8021
Genome polyprotein O92972 POLG_HCVJ4 Hepatitis C virus genotype 1b 3 0.7990
Genome polyprotein O92972 POLG_HCVJ4 Hepatitis C virus genotype 1b 3 0.7990
Epidermal growth factor receptor P00533 EGFR_HUMAN Homo sapiens 3 0.7978
Epidermal growth factor receptor P00533 EGFR_HUMAN Homo sapiens 3 0.7978
Pancreatic alpha-amylase P04746 AMYP_HUMAN Homo sapiens 3 0.7968
Pancreatic alpha-amylase P04746 AMYP_HUMAN Homo sapiens 3 0.7968
17beta-hydroxysteroid dehydrogenase O93874 O93874_COCLU Cochliobolus lunatus 3 0.7966
17beta-hydroxysteroid dehydrogenase O93874 O93874_COCLU Cochliobolus lunatus 3 0.7966
Poly [ADP-ribose] polymerase tankyrase-2 Q9H2K2 TNKS2_HUMAN Homo sapiens 4 0.7949
Poly [ADP-ribose] polymerase tankyrase-2 Q9H2K2 TNKS2_HUMAN Homo sapiens 4 0.7949
DNA topoisomerase 4 subunit B H7C794 PARE_ENTFA Enterococcus faecalis 3 0.7925
DNA topoisomerase 4 subunit B H7C794 PARE_ENTFA Enterococcus faecalis 3 0.7925
HTH-type transcriptional repressor PurR P0ACP7 PURR_ECOLI Escherichia coli 3 0.7914
HTH-type transcriptional repressor PurR P0ACP7 PURR_ECOLI Escherichia coli 3 0.7914
Anthocyanidin 3-O-glucosyltransferase UFGT P51094 UFOG_VITVI Vitis vinifera 3 0.7908
Anthocyanidin 3-O-glucosyltransferase UFGT P51094 UFOG_VITVI Vitis vinifera 3 0.7908
Steroid Delta-isomerase P00947 SDIS_COMTE Comamonas testosteroni 3 0.7899
Steroid Delta-isomerase P00947 SDIS_COMTE Comamonas testosteroni 3 0.7899
cGMP-specific 3',5'-cyclic phosphodiesterase O76074 PDE5A_HUMAN Homo sapiens 3 0.7886
cGMP-specific 3',5'-cyclic phosphodiesterase O76074 PDE5A_HUMAN Homo sapiens 3 0.7886
Secoisolariciresinol dehydrogenase Q94KL8 SILD_PODPE Podophyllum peltatum 4 0.7860
Secoisolariciresinol dehydrogenase Q94KL8 SILD_PODPE Podophyllum peltatum 4 0.7860
4,4'-diapophytoene synthase A9JQL9 CRTM_STAAU Staphylococcus aureus 3 0.7858
4,4'-diapophytoene synthase A9JQL9 CRTM_STAAU Staphylococcus aureus 3 0.7858
Ras-related protein Ral-B P11234 RALB_HUMAN Homo sapiens 3 0.7849
Ras-related protein Ral-B P11234 RALB_HUMAN Homo sapiens 3 0.7849
Poly [ADP-ribose] polymerase tankyrase-2 Q9H2K2 TNKS2_HUMAN Homo sapiens 5 0.7843
Poly [ADP-ribose] polymerase tankyrase-2 Q9H2K2 TNKS2_HUMAN Homo sapiens 5 0.7843
Mitogen-activated protein kinase 14 Q16539 MK14_HUMAN Homo sapiens 3 0.7828
Mitogen-activated protein kinase 14 Q16539 MK14_HUMAN Homo sapiens 3 0.7828
Dihydroflavonol 4-reductase P51110 DFRA_VITVI Vitis vinifera 7 0.7824
Dihydroflavonol 4-reductase P51110 DFRA_VITVI Vitis vinifera 7 0.7824
Mitogen-activated protein kinase 1 P28482 MK01_HUMAN Homo sapiens 3 0.7821
Mitogen-activated protein kinase 1 P28482 MK01_HUMAN Homo sapiens 3 0.7821
Ribonuclease J H9CZL7 H9CZL7_DEIRD Deinococcus radiodurans 3 0.7804
Ribonuclease J H9CZL7 H9CZL7_DEIRD Deinococcus radiodurans 3 0.7804
Focal adhesion kinase 1 Q05397 FAK1_HUMAN Homo sapiens 3 0.7786
Focal adhesion kinase 1 Q05397 FAK1_HUMAN Homo sapiens 3 0.7786
Protein polybromo-1 Q86U86 PB1_HUMAN Homo sapiens 5 0.7736
Protein polybromo-1 Q86U86 PB1_HUMAN Homo sapiens 5 0.7736
Fibroblast growth factor receptor 1 P11362 FGFR1_HUMAN Homo sapiens 3 0.7729
Fibroblast growth factor receptor 1 P11362 FGFR1_HUMAN Homo sapiens 3 0.7729
Lactotransferrin P24627 TRFL_BOVIN Bos taurus 2 0.7729
Lactotransferrin P24627 TRFL_BOVIN Bos taurus 2 0.7729
Gag-Pol polyprotein P12497 POL_HV1N5 Human immunodeficiency virus type 1 group M subtype B 3 0.7706
Gag-Pol polyprotein P12497 POL_HV1N5 Human immunodeficiency virus type 1 group M subtype B 3 0.7706
Epidermal growth factor receptor P00533 EGFR_HUMAN Homo sapiens 3 0.7706
Epidermal growth factor receptor P00533 EGFR_HUMAN Homo sapiens 3 0.7706
Flavoredoxin Q72HI0 Q72HI0_THET2 Thermus thermophilus 3 0.7653
Flavoredoxin Q72HI0 Q72HI0_THET2 Thermus thermophilus 3 0.7653
Fibroblast growth factor receptor 2 P21802 FGFR2_HUMAN Homo sapiens 3 0.7642
Fibroblast growth factor receptor 2 P21802 FGFR2_HUMAN Homo sapiens 3 0.7642
Cyclin-dependent kinase 9 P50750 CDK9_HUMAN Homo sapiens 3 0.7620
Cyclin-dependent kinase 9 P50750 CDK9_HUMAN Homo sapiens 3 0.7620
Poly [ADP-ribose] polymerase tankyrase-2 Q9H2K2 TNKS2_HUMAN Homo sapiens 4 0.7616
Poly [ADP-ribose] polymerase tankyrase-2 Q9H2K2 TNKS2_HUMAN Homo sapiens 4 0.7616
Prothrombin P00734 THRB_HUMAN Homo sapiens 3 0.7589
Prothrombin P00734 THRB_HUMAN Homo sapiens 3 0.7589
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform O02697 PK3CG_PIG Sus scrofa 5 0.7567
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform O02697 PK3CG_PIG Sus scrofa 5 0.7567
Genome polyprotein Q2YHF0 POLG_DEN4T Dengue virus type 4 3 0.7535
Genome polyprotein Q2YHF0 POLG_DEN4T Dengue virus type 4 3 0.7535
Ephrin type-B receptor 2 P54763 EPHB2_MOUSE Mus musculus 3 0.7528
Ephrin type-B receptor 2 P54763 EPHB2_MOUSE Mus musculus 3 0.7528
GTP 3',8-cyclase P69848 MOAA_STAA8 Staphylococcus aureus 4 0.7526
GTP 3',8-cyclase P69848 MOAA_STAA8 Staphylococcus aureus 4 0.7526
HTH-type transcriptional repressor PurR P0ACP7 PURR_ECOLI Escherichia coli 3 0.7525
HTH-type transcriptional repressor PurR P0ACP7 PURR_ECOLI Escherichia coli 3 0.7525
APH(2'')-Id O68183 O68183_ENTCA Enterococcus casseliflavus 4 0.7521
APH(2'')-Id O68183 O68183_ENTCA Enterococcus casseliflavus 4 0.7521
Polyprotein Q80J95 Q80J95_9CALI Murine norovirus 1 3 0.7514
Polyprotein Q80J95 Q80J95_9CALI Murine norovirus 1 3 0.7514
DNA gyrase subunit B Q839Z1 GYRB_ENTFA Enterococcus faecalis 3 0.7512
DNA gyrase subunit B Q839Z1 GYRB_ENTFA Enterococcus faecalis 3 0.7512
Beta-glucosidase 12 B8AVF0 BGL12_ORYSI Oryza sativa subsp. indica 3 0.7509
Beta-glucosidase 12 B8AVF0 BGL12_ORYSI Oryza sativa subsp. indica 3 0.7509
High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A O76083 PDE9A_HUMAN Homo sapiens 3 0.7505
High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A O76083 PDE9A_HUMAN Homo sapiens 3 0.7505
Riboflavin synthase P0AFU8 RISA_ECOLI Escherichia coli 3 0.7494
Riboflavin synthase P0AFU8 RISA_ECOLI Escherichia coli 3 0.7494
Peroxisome proliferator-activated receptor gamma P37231 PPARG_HUMAN Homo sapiens 4 0.7480
Peroxisome proliferator-activated receptor gamma P37231 PPARG_HUMAN Homo sapiens 4 0.7480
Carbonic anhydrase 2 P00918 CAH2_HUMAN Homo sapiens 2 0.7479
Carbonic anhydrase 2 P00918 CAH2_HUMAN Homo sapiens 2 0.7479
Tubulin alpha-1B chain P81947 TBA1B_BOVIN Bos taurus 4 0.7476
Tubulin alpha-1B chain P81947 TBA1B_BOVIN Bos taurus 4 0.7476
Biflaviolin synthase CYP158A1 Q9KZF5 C1581_STRCO Streptomyces coelicolor / M145) 3 0.7464
Biflaviolin synthase CYP158A1 Q9KZF5 C1581_STRCO Streptomyces coelicolor / M145) 3 0.7464
Chalcone--flavanone isomerase 1 P28012 CFI1_MEDSA Medicago sativa 3 0.7461
Chalcone--flavanone isomerase 1 P28012 CFI1_MEDSA Medicago sativa 3 0.7461
tyrosine--tRNA ligase Q4QFJ7 Q4QFJ7_LEIMA Leishmania major 3 0.7435
tyrosine--tRNA ligase Q4QFJ7 Q4QFJ7_LEIMA Leishmania major 3 0.7435
Cis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase Q46381 BPHB_COMTE Comamonas testosteroni 3 0.7432
Cis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase Q46381 BPHB_COMTE Comamonas testosteroni 3 0.7432
Epidermal growth factor receptor P00533 EGFR_HUMAN Homo sapiens 3 0.7424
Death-associated protein kinase 1 P53355 DAPK1_HUMAN Homo sapiens 3 0.7424
Epidermal growth factor receptor P00533 EGFR_HUMAN Homo sapiens 3 0.7424
Death-associated protein kinase 1 P53355 DAPK1_HUMAN Homo sapiens 3 0.7424
Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplastic Q43088 RBCMT_PEA Pisum sativum 3 0.7420
Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplastic Q43088 RBCMT_PEA Pisum sativum 3 0.7420
Polyamine aminopropyltransferase Q5SK28 SPEE_THET8 Thermus thermophilus 4 0.7405
Polyamine aminopropyltransferase Q5SK28 SPEE_THET8 Thermus thermophilus 4 0.7405
Hypoxanthine phosphoribosyltransferase Q4DRC4 Q4DRC4_TRYCC Trypanosoma cruzi 3 0.7390
Mitogen-activated protein kinase kinase kinase 5 Q99683 M3K5_HUMAN Homo sapiens 3 0.7390
Hypoxanthine phosphoribosyltransferase Q4DRC4 Q4DRC4_TRYCC Trypanosoma cruzi 3 0.7390
Mitogen-activated protein kinase kinase kinase 5 Q99683 M3K5_HUMAN Homo sapiens 3 0.7390
Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase Q05603 COBT_SALTY Salmonella typhimurium 2 0.7383
Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase Q05603 COBT_SALTY Salmonella typhimurium 2 0.7383
DNA polymerase theta O75417 DPOLQ_HUMAN Homo sapiens 4 0.7357
Bromodomain-containing protein 2 P25440 BRD2_HUMAN Homo sapiens 3 0.7357
Bromodomain-containing protein 2 P25440 BRD2_HUMAN Homo sapiens 3 0.7357
DNA polymerase theta O75417 DPOLQ_HUMAN Homo sapiens 4 0.7357
NADPH--cytochrome P450 reductase P00388 NCPR_RAT Rattus norvegicus 4 0.7356
NADPH--cytochrome P450 reductase P00388 NCPR_RAT Rattus norvegicus 4 0.7356
Tyrosine-protein kinase JAK2 O60674 JAK2_HUMAN Homo sapiens 3 0.7353
Tyrosine-protein kinase JAK2 O60674 JAK2_HUMAN Homo sapiens 3 0.7353
Replicase polyprotein 1ab P0C6X7 R1AB_CVHSA Human SARS coronavirus 4 0.7348
Replicase polyprotein 1ab P0C6X7 R1AB_CVHSA Human SARS coronavirus 4 0.7348
Serine/threonine-protein kinase Chk1 O14757 CHK1_HUMAN Homo sapiens 3 0.7347
Serine/threonine-protein kinase Chk1 O14757 CHK1_HUMAN Homo sapiens 3 0.7347
Beta-galactosidase P00722 BGAL_ECOLI Escherichia coli 3 0.7323
Beta-galactosidase P00722 BGAL_ECOLI Escherichia coli 3 0.7323
Succinate dehydrogenase flavoprotein subunit P0AC41 SDHA_ECOLI Escherichia coli 3 0.7316
Succinate dehydrogenase flavoprotein subunit P0AC41 SDHA_ECOLI Escherichia coli 3 0.7316
Poly [ADP-ribose] polymerase tankyrase-2 Q9H2K2 TNKS2_HUMAN Homo sapiens 5 0.7311
Poly [ADP-ribose] polymerase tankyrase-2 Q9H2K2 TNKS2_HUMAN Homo sapiens 5 0.7311
Bromodomain-containing protein 4 O60885 BRD4_HUMAN Homo sapiens 3 0.7307
Bromodomain-containing protein 4 O60885 BRD4_HUMAN Homo sapiens 3 0.7307
Uridine phosphorylase Q9KT71 Q9KT71_VIBCH Vibrio cholerae serotype O1 4 0.7301
Uridine phosphorylase Q9KT71 Q9KT71_VIBCH Vibrio cholerae serotype O1 4 0.7301
Dual specificity mitogen-activated protein kinase kinase 1 Q02750 MP2K1_HUMAN Homo sapiens 3 0.7288
Dual specificity mitogen-activated protein kinase kinase 1 Q02750 MP2K1_HUMAN Homo sapiens 3 0.7288
Aminoglycoside N(3)-acetyltransferase A0A3P1UCA6 Q81P86_BACAN Bacillus anthracis 3 0.7276
Aminoglycoside N(3)-acetyltransferase A0A3P1UCA6 Q81P86_BACAN Bacillus anthracis 3 0.7276
Aldehyde dehydrogenase, mitochondrial P05091 ALDH2_HUMAN Homo sapiens 3 0.7261
Aldehyde dehydrogenase, mitochondrial P05091 ALDH2_HUMAN Homo sapiens 3 0.7261
Proto-oncogene tyrosine-protein kinase Src P00523 SRC_CHICK Gallus gallus 3 0.7259
Proto-oncogene tyrosine-protein kinase Src P00523 SRC_CHICK Gallus gallus 3 0.7259
Phosphoenolpyruvate carboxykinase [GTP] A5TYT6 PCKG_MYCTA Mycobacterium tuberculosis 3 0.7254
Phosphoenolpyruvate carboxykinase [GTP] A5TYT6 PCKG_MYCTA Mycobacterium tuberculosis 3 0.7254
Phosphodiesterase Q8WQX9 Q8WQX9_9TRYP Trypanosoma brucei 3 0.7253
Phosphodiesterase Q8WQX9 Q8WQX9_9TRYP Trypanosoma brucei 3 0.7253
Heat shock protein 75 kDa, mitochondrial Q12931 TRAP1_HUMAN Homo sapiens 4 0.7251
Heat shock protein 75 kDa, mitochondrial Q12931 TRAP1_HUMAN Homo sapiens 4 0.7251
Nucleoprotein P33469 NCAP_CVHOC Human coronavirus OC43 3 0.7247
Nucleoprotein P33469 NCAP_CVHOC Human coronavirus OC43 3 0.7247
Nitric oxide synthase 1 P29476 NOS1_RAT Rattus norvegicus 3 0.7246
Nitric oxide synthase 1 P29476 NOS1_RAT Rattus norvegicus 3 0.7246
Purine nucleoside phosphorylase P00491 PNPH_HUMAN Homo sapiens 3 0.7244
Purine nucleoside phosphorylase P00491 PNPH_HUMAN Homo sapiens 3 0.7244
Chitinase A Q9AMP1 Q9AMP1_VIBHA Vibrio harveyi 2 0.7234
Chitinase A Q9AMP1 Q9AMP1_VIBHA Vibrio harveyi 2 0.7234
Polymerase acidic protein C3W5S0 C3W5S0_I09A0 Influenza A virus 2 0.7233
Death-associated protein kinase 1 P53355 DAPK1_HUMAN Homo sapiens 3 0.7233
Polymerase acidic protein C3W5S0 C3W5S0_I09A0 Influenza A virus 2 0.7233
Death-associated protein kinase 1 P53355 DAPK1_HUMAN Homo sapiens 3 0.7233
Tetracycline repressor protein class D P0ACT4 TETR4_ECOLX Escherichia coli 3 0.7232
Tetracycline repressor protein class D P0ACT4 TETR4_ECOLX Escherichia coli 3 0.7232
Serine/threonine-protein kinase pim-1 P11309 PIM1_HUMAN Homo sapiens 4 0.7224
Serine/threonine-protein kinase pim-1 P11309 PIM1_HUMAN Homo sapiens 4 0.7224
Nucleoside phosphorylase, putative Q57VZ2 Q57VZ2_TRYB2 Trypanosoma brucei brucei 4 0.7223
Nucleoside phosphorylase, putative Q57VZ2 Q57VZ2_TRYB2 Trypanosoma brucei brucei 4 0.7223
Poly [ADP-ribose] polymerase tankyrase-2 Q9H2K2 TNKS2_HUMAN Homo sapiens 4 0.7222
Poly [ADP-ribose] polymerase tankyrase-2 Q9H2K2 TNKS2_HUMAN Homo sapiens 4 0.7222
Glucose-1-phosphate thymidylyltransferase Q9HU22 Q9HU22_PSEAE Pseudomonas aeruginosa 4 0.7213
Poly [ADP-ribose] polymerase tankyrase-2 Q9H2K2 TNKS2_HUMAN Homo sapiens 4 0.7213
Glucose-1-phosphate thymidylyltransferase Q9HU22 Q9HU22_PSEAE Pseudomonas aeruginosa 4 0.7213
Poly [ADP-ribose] polymerase tankyrase-2 Q9H2K2 TNKS2_HUMAN Homo sapiens 4 0.7213
Carbonic anhydrase 2 P00918 CAH2_HUMAN Homo sapiens 3 0.7211
Carbonic anhydrase 2 P00918 CAH2_HUMAN Homo sapiens 3 0.7211
Bromodomain-containing protein 4 O60885 BRD4_HUMAN Homo sapiens 3 0.7206
Bromodomain-containing protein 4 O60885 BRD4_HUMAN Homo sapiens 3 0.7206
Tetracycline repressor protein class D P0ACT4 TETR4_ECOLX Escherichia coli 3 0.7203
Tetracycline repressor protein class D P0ACT4 TETR4_ECOLX Escherichia coli 3 0.7203
cAMP-dependent protein kinase catalytic subunit alpha P00517 KAPCA_BOVIN Bos taurus 3 0.7201
cAMP-dependent protein kinase catalytic subunit alpha P00517 KAPCA_BOVIN Bos taurus 3 0.7201
Phosphoenolpyruvate carboxykinase [GTP] P9WIH3 PCKG_MYCTU Mycobacterium tuberculosis 3 0.7200
Phosphoenolpyruvate carboxykinase [GTP] P9WIH3 PCKG_MYCTU Mycobacterium tuberculosis 3 0.7200
Peripheral plasma membrane protein CASK O14936 CSKP_HUMAN Homo sapiens 3 0.7200
Peripheral plasma membrane protein CASK O14936 CSKP_HUMAN Homo sapiens 3 0.7200
Cyclin-dependent kinase 2 P24941 CDK2_HUMAN Homo sapiens 3 0.7195
Cyclin-dependent kinase 2 P24941 CDK2_HUMAN Homo sapiens 3 0.7195
Serine/threonine-protein kinase pim-1 P11309 PIM1_HUMAN Homo sapiens 3 0.7190
Serine/threonine-protein kinase pim-1 P11309 PIM1_HUMAN Homo sapiens 3 0.7190
Ribosomal RNA large subunit methyltransferase J P37634 RLMJ_ECOLI Escherichia coli 4 0.7187
Ribosomal RNA large subunit methyltransferase J P37634 RLMJ_ECOLI Escherichia coli 4 0.7187
Gag-Pol polyprotein P12497 POL_HV1N5 Human immunodeficiency virus type 1 group M subtype B 2 0.7185
Gag-Pol polyprotein P12497 POL_HV1N5 Human immunodeficiency virus type 1 group M subtype B 2 0.7185
Serine/threonine-protein kinase Chk1 O14757 CHK1_HUMAN Homo sapiens 3 0.7184
Serine/threonine-protein kinase Chk1 O14757 CHK1_HUMAN Homo sapiens 3 0.7184
Tetracycline repressor protein class D P0ACT4 TETR4_ECOLX Escherichia coli 2 0.7179
Tetracycline repressor protein class D P0ACT4 TETR4_ECOLX Escherichia coli 2 0.7179
Histidine kinase 4 Q9C5U0 AHK4_ARATH Arabidopsis thaliana 3 0.7171
Histidine kinase 4 Q9C5U0 AHK4_ARATH Arabidopsis thaliana 3 0.7171
Rho family GTPase C4M4W4 C4M4W4_ENTHI Entamoeba histolytica 4 0.7168
Rho family GTPase C4M4W4 C4M4W4_ENTHI Entamoeba histolytica 4 0.7168
Mycocyclosin synthase P9WPP7 CP121_MYCTU Mycobacterium tuberculosis 3 0.7166
Mycocyclosin synthase P9WPP7 CP121_MYCTU Mycobacterium tuberculosis 3 0.7166
Heat shock protein HSP 90-alpha P07900 HS90A_HUMAN Homo sapiens 3 0.7149
Heat shock protein HSP 90-alpha P07900 HS90A_HUMAN Homo sapiens 3 0.7149
Type II methyltransferase M.HhaI P05102 MTH1_HAEPH Haemophilus parahaemolyticus 4 0.7146
Type II methyltransferase M.HhaI P05102 MTH1_HAEPH Haemophilus parahaemolyticus 4 0.7146
Heat shock protein HSP 90-beta P08238 HS90B_HUMAN Homo sapiens 3 0.7140
Heat shock protein HSP 90-beta P08238 HS90B_HUMAN Homo sapiens 3 0.7140
Tyrosine-protein kinase SYK P43405 KSYK_HUMAN Homo sapiens 5 0.7136
Tyrosine-protein kinase SYK P43405 KSYK_HUMAN Homo sapiens 5 0.7136
2-aminohexano-6-lactam racemase Q7M181 ACLR_ACHOB Achromobacter obae 3 0.7135
Glutathione S-transferase F2 P46422 GSTF2_ARATH Arabidopsis thaliana 3 0.7135
2-aminohexano-6-lactam racemase Q7M181 ACLR_ACHOB Achromobacter obae 3 0.7135
Glutathione S-transferase F2 P46422 GSTF2_ARATH Arabidopsis thaliana 3 0.7135
Poly [ADP-ribose] polymerase tankyrase-2 Q9H2K2 TNKS2_HUMAN Homo sapiens 4 0.7130
Poly [ADP-ribose] polymerase tankyrase-2 Q9H2K2 TNKS2_HUMAN Homo sapiens 4 0.7130
Heat shock protein HSP 90-alpha P07900 HS90A_HUMAN Homo sapiens 3 0.7129
Heat shock protein HSP 90-alpha P07900 HS90A_HUMAN Homo sapiens 3 0.7129
Cell division cycle 7-related protein kinase O00311 CDC7_HUMAN Homo sapiens 4 0.7123
Cell division cycle 7-related protein kinase O00311 CDC7_HUMAN Homo sapiens 4 0.7123
Chalcone synthase 2 P30074 CHS2_MEDSA Medicago sativa 4 0.7103
Hypoxanthine-guanine phosphoribosyltransferase P00492 HPRT_HUMAN Homo sapiens 3 0.7103
Chalcone synthase 2 P30074 CHS2_MEDSA Medicago sativa 4 0.7103
Hypoxanthine-guanine phosphoribosyltransferase P00492 HPRT_HUMAN Homo sapiens 3 0.7103
Ribosyldihydronicotinamide dehydrogenase [quinone] P16083 NQO2_HUMAN Homo sapiens 2 0.7102
Ribosyldihydronicotinamide dehydrogenase [quinone] P16083 NQO2_HUMAN Homo sapiens 2 0.7102
DNA-directed DNA polymerase Q38087 DPOL_BPR69 Escherichia phage RB69 2 0.7100
DNA-directed DNA polymerase Q38087 DPOL_BPR69 Escherichia phage RB69 2 0.7100
SKP1-like protein 1A Q39255 SKP1A_ARATH Arabidopsis thaliana 3 0.7098
SKP1-like protein 1A Q39255 SKP1A_ARATH Arabidopsis thaliana 3 0.7098
Carbonic anhydrase 2 P00918 CAH2_HUMAN Homo sapiens 2 0.7096
Carbonic anhydrase 2 P00918 CAH2_HUMAN Homo sapiens 2 0.7096
cGMP-dependent 3',5'-cyclic phosphodiesterase O00408 PDE2A_HUMAN Homo sapiens 3 0.7086
cGMP-dependent 3',5'-cyclic phosphodiesterase O00408 PDE2A_HUMAN Homo sapiens 3 0.7086
Casein kinase II subunit alpha P68400 CSK21_HUMAN Homo sapiens 4 0.7080
Casein kinase II subunit alpha P68400 CSK21_HUMAN Homo sapiens 4 0.7080
Heat shock protein HSP 90-alpha P07900 HS90A_HUMAN Homo sapiens 3 0.7072
Heat shock protein HSP 90-alpha P07900 HS90A_HUMAN Homo sapiens 3 0.7072
Serine/threonine-protein kinase pim-1 P11309 PIM1_HUMAN Homo sapiens 4 0.7070
Serine/threonine-protein kinase pim-1 P11309 PIM1_HUMAN Homo sapiens 4 0.7070
HTH-type transcriptional regulator TtgR Q9AIU0 TTGR_PSEPT Pseudomonas putida 3 0.7060
HTH-type transcriptional regulator TtgR Q9AIU0 TTGR_PSEPT Pseudomonas putida 3 0.7060
dTDP-4-dehydrorhamnose 3,5-epimerase A0A6L7H6N0 A0A1S0QLH9_BACAN Bacillus anthracis 3 0.7056
dTDP-4-dehydrorhamnose 3,5-epimerase A0A6L7H6N0 A0A1S0QLH9_BACAN Bacillus anthracis 3 0.7056
Hypoxanthine-guanine phosphoribosyltransferase P00492 HPRT_HUMAN Homo sapiens 3 0.7052
Hypoxanthine-guanine phosphoribosyltransferase P00492 HPRT_HUMAN Homo sapiens 3 0.7052
Histone-lysine N-methyltransferase SETD7 Q8WTS6 SETD7_HUMAN Homo sapiens 3 0.7034
Histone-lysine N-methyltransferase SETD7 Q8WTS6 SETD7_HUMAN Homo sapiens 3 0.7034
Aminoglycoside 3'-phosphotransferase AphA1-IAB B0VD92 B0VD92_ACIBY Acinetobacter baumannii 3 0.7033
Aminoglycoside 3'-phosphotransferase AphA1-IAB B0VD92 B0VD92_ACIBY Acinetobacter baumannii 3 0.7033
Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplastic Q43088 RBCMT_PEA Pisum sativum 3 0.7030
Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplastic Q43088 RBCMT_PEA Pisum sativum 3 0.7030
Fibroblast growth factor receptor 2 P21802 FGFR2_HUMAN Homo sapiens 3 0.7023
Fibroblast growth factor receptor 2 P21802 FGFR2_HUMAN Homo sapiens 3 0.7023
Beta-galactoside-specific lectin 4 Q6ITZ3 ML4_VISAL Viscum album 2 0.7021
Beta-galactoside-specific lectin 4 Q6ITZ3 ML4_VISAL Viscum album 2 0.7021
Glycogen synthase kinase-3 beta P49841 GSK3B_HUMAN Homo sapiens 3 0.7007
Glycogen synthase kinase-3 beta P49841 GSK3B_HUMAN Homo sapiens 3 0.7007
APH(2'')-Id O68183 O68183_ENTCA Enterococcus casseliflavus 3 0.7006
APH(2'')-Id O68183 O68183_ENTCA Enterococcus casseliflavus 3 0.7006

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