Apigenin 7-O-beta-neohespredoside - Compound Card

Apigenin 7-O-beta-neohespredoside

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Apigenin 7-O-beta-neohespredoside

Structure
Zoomed Structure
  • Family: Plantae - Euphorbiaceae
  • Kingdom: Plantae
  • Class: Flavonoid
    • Subclass: Flavonoid Glycoside
Canonical Smiles OC[C@H]1O[C@@H](Oc2cc(O)c3c(c2)oc(cc3=O)c2ccc(cc2)O)[C@@H]([C@H]([C@@H]1O)O)O[C@@H]1C[C@@H](C)[C@@H]([C@H]([C@H]1O)O)O
InChI InChI=1S/C28H32O13/c1-11-6-19(23(34)25(36)22(11)33)40-27-26(37)24(35)20(10-29)41-28(27)38-14-7-15(31)21-16(32)9-17(39-18(21)8-14)12-2-4-13(30)5-3-12/h2-5,7-9,11,19-20,22-31,33-37H,6,10H2,1H3/t11-,19-,20-,22+,23+,24-,25-,26+,27-,28-/m1/s1
InChIKey SMGMSKBCDUOVJD-NUEKVCAZSA-N
Formula C28H32O13
HBA 13
HBD 8
MW 576.55
Rotatable Bonds 6
TPSA 219.74
LogP -0.43
Number Rings 5
Number Aromatic Rings 3
Heavy Atom Count 41
Formal Charge 0
Fraction CSP3 0.46
Exact Mass 576.18
Number of Lipinski Rule Violations 3
# Species Family Kingdom NCBI Taxonomy ID
1 Euphorbia helioscopia Euphorbiaceae Plantae 154990

Showing of synonyms

  • Mohamed AH, Hegazy MF, et al. (2012). Euphorbia helioscopia: Chemical constituents and biological activities. International Journal of Phytopharmacology,2012,3(1),78-90. [View]
Pubchem: 162817269

No compound-protein relationship available.

Structure

SMILES: c1ccccc1-c(cc2=O)oc(c23)cc(cc3)OC(OCCC4)C4OC5CCCCC5

Level: 3

Mol. Weight: 576.55 g/mol

Structure

SMILES: O=c1ccoc(c12)cc(cc2)OC(OCCC3)C3OC4CCCCC4

Level: 2

Mol. Weight: 576.55 g/mol

Structure

SMILES: c1ccccc1-c(cc2=O)oc(c23)cc(cc3)OC4CCCCO4

Level: 2

Mol. Weight: 576.55 g/mol

Structure

SMILES: O=c1ccoc(c12)cc(cc2)OC3CCCCO3

Level: 1

Mol. Weight: 576.55 g/mol

Structure

SMILES: c1cccc(c12)oc(cc2=O)-c3ccccc3

Level: 1

Mol. Weight: 576.55 g/mol

Structure

SMILES: C1CCCCC1OC2CCCOC2

Level: 1

Mol. Weight: 576.55 g/mol

Structure

SMILES: c1cccc(c12)occc2=O

Level: 0

Mol. Weight: 576.55 g/mol

Structure

SMILES: C1CCOCC1

Level: 0

Mol. Weight: 576.55 g/mol

Structure

SMILES: C1CCCCC1

Level: 0

Mol. Weight: 576.55 g/mol

Structure

SMILES: c1ccccc1

Level: 0

Mol. Weight: 576.55 g/mol

No bioactivities available.

Absorption

Caco-2 (logPapp)
-6.66
Human Oral Bioavailability 20%
Non-Bioavailable
Human Intestinal Absorption
Non-Absorbed
Madin-Darby Canine Kidney
-5.260
Human Oral Bioavailability 50%
Non-Bioavailable
P-Glycoprotein Inhibitor
Non-Inhibitor
P-Glycoprotein Substrate
Substrate
Skin Permeability
4.39

Distribution

Blood-Brain Barrier (CNS)
-
Blood-Brain Barrier
Non-Penetrable
Fraction Unbound (Human)
0.930
Plasma Protein Binding
82.1
Steady State Volume of Distribution
-

Metabolism

Breast Cancer Resistance Protein
Non-Inhibitor
CYP 1A2 Inhibitor
Non-Inhibitor
CYP 1A2 Substrate
Non-Substrate
CYP 2C19 Inhibitor
Non-Inhibitor
CYP 2C19 Substrate
Non-Substrate
CYP 2C9 Inhibitor
Non-Inhibitor
CYP 2C9 Substrate
Non-Substrate
CYP 2D6 Inhibitor
Non-Inhibitor
CYP 2D6 Substrate
Non-Substrate
CYP 3A4 Inhibitor
Non-Inhibitor
CYP 3A4 Substrate
Non-Substrate
OATP1B1
Non-Inhibitor
OATP1B3
Non-Inhibitor

Excretion

Clearance
9.340
Organic Cation Transporter 2
Non-Inhibitor
Half-Life of Drug
-

Toxicity

AMES Mutagenesis
Safe
Avian
Safe
Bee
Toxic
Bioconcentration Factor
-2.790
Biodegradation
Safe
Carcinogenesis
Safe
Crustacean
Safe
Liver Injury I (DILI)
Safe
Eye Corrosion
Safe
Eye Irritation
Safe
Maximum Tolerated Dose
0.760
Liver Injury II
Toxic
hERG Blockers
Toxic
Daphnia Maga
5.070
Micronucleos
Toxic
NR-AhR
Safe
NR-AR
Safe
NR-AR-LBD
Safe
NR-Aromatase
Safe
NR-ER
Safe
NR-ER-LBD
Safe
NR-GR
Safe
NR-PPAR-gamma
Safe
NR-TR
Safe
T. Pyriformis
-6205.250
Rat (Acute)
2.620
Rat (Chronic Oral)
3.810
Fathead Minnow
14.800
Respiratory Disease
Safe
Skin Sensitisation
Safe
SR-ARE
Safe
SR-ATAD5
Safe
SR-HSE
Safe
SR-MMP
Safe
SR-p53
Safe

General Properties

Boiling Point
537.010
Hydration Free Energy
-3.020
Log(D) at pH=7.4
1.130
Log(P)
0.84
Log S
-4.44
Log(Vapor Pressure)
-11.64
Melting Point
197.29
pKa Acid
4.74
pKa Basic
6.6
Protein Name UniProt ID Entry Name Species #Pharmacophore Points Probability (0.7 ≤ Tversky Score ≤ 1.0)
Cathepsin S P25774 CATS_HUMAN Homo sapiens 3 0.9504
Cathepsin S P25774 CATS_HUMAN Homo sapiens 3 0.9504
Histone deacetylase 4 P56524 HDAC4_HUMAN Homo sapiens 3 0.9492
Histone deacetylase 4 P56524 HDAC4_HUMAN Homo sapiens 3 0.9492
Glycogen phosphorylase, muscle form P00489 PYGM_RABIT Oryctolagus cuniculus 3 0.9249
Glycogen phosphorylase, muscle form P00489 PYGM_RABIT Oryctolagus cuniculus 3 0.9249
3',5'-cyclic-AMP phosphodiesterase 4D Q08499 PDE4D_HUMAN Homo sapiens 4 0.8968
3',5'-cyclic-AMP phosphodiesterase 4D Q08499 PDE4D_HUMAN Homo sapiens 4 0.8968
3',5'-cyclic-AMP phosphodiesterase 4D Q08499 PDE4D_HUMAN Homo sapiens 3 0.8938
3',5'-cyclic-AMP phosphodiesterase 4D Q08499 PDE4D_HUMAN Homo sapiens 3 0.8938
Carbonic anhydrase 2 P00918 CAH2_HUMAN Homo sapiens 3 0.8786
Carbonic anhydrase 2 P00918 CAH2_HUMAN Homo sapiens 3 0.8786
Methionine aminopeptidase 1 P53582 MAP11_HUMAN Homo sapiens 3 0.8765
Methionine aminopeptidase 1 P53582 MAP11_HUMAN Homo sapiens 3 0.8765
Death-associated protein kinase 1 P53355 DAPK1_HUMAN Homo sapiens 4 0.8716
Death-associated protein kinase 1 P53355 DAPK1_HUMAN Homo sapiens 4 0.8716
Capsid protein Q9WBP8 Q9WBP8_9VIRU Adeno-associated virus - 1 3 0.8706
Capsid protein Q9WBP8 Q9WBP8_9VIRU Adeno-associated virus - 1 3 0.8706
MAP kinase-activated protein kinase 2 P49137 MAPK2_HUMAN Homo sapiens 3 0.8690
MAP kinase-activated protein kinase 2 P49137 MAPK2_HUMAN Homo sapiens 3 0.8690
Tyrosine-protein kinase JAK3 P52333 JAK3_HUMAN Homo sapiens 3 0.8629
Serine/threonine-protein kinase SKY1 Q03656 SKY1_YEAST Saccharomyces cerevisiae 3 0.8629
Tyrosine-protein kinase JAK3 P52333 JAK3_HUMAN Homo sapiens 3 0.8629
Serine/threonine-protein kinase SKY1 Q03656 SKY1_YEAST Saccharomyces cerevisiae 3 0.8629
Bromodomain adjacent to zinc finger domain protein 2B Q9UIF8 BAZ2B_HUMAN Homo sapiens 3 0.8599
Bromodomain adjacent to zinc finger domain protein 2B Q9UIF8 BAZ2B_HUMAN Homo sapiens 3 0.8599
Steroid Delta-isomerase P00947 SDIS_COMTE Comamonas testosteroni 3 0.8532
Steroid Delta-isomerase P00947 SDIS_COMTE Comamonas testosteroni 3 0.8532
Valacyclovir hydrolase Q86WA6 BPHL_HUMAN Homo sapiens 3 0.8489
Valacyclovir hydrolase Q86WA6 BPHL_HUMAN Homo sapiens 3 0.8489
Steroid Delta-isomerase P00947 SDIS_COMTE Comamonas testosteroni 3 0.8410
Steroid Delta-isomerase P00947 SDIS_COMTE Comamonas testosteroni 3 0.8410
Carbonic anhydrase 2 P00918 CAH2_HUMAN Homo sapiens 3 0.8358
Carbonic anhydrase 2 P00918 CAH2_HUMAN Homo sapiens 3 0.8358
Pantothenate synthetase P9WIL5 PANC_MYCTU Mycobacterium tuberculosis 3 0.8337
Pantothenate synthetase P9WIL5 PANC_MYCTU Mycobacterium tuberculosis 3 0.8337
3',5'-cyclic-AMP phosphodiesterase 4D Q08499 PDE4D_HUMAN Homo sapiens 3 0.8326
3',5'-cyclic-AMP phosphodiesterase 4D Q08499 PDE4D_HUMAN Homo sapiens 3 0.8326
Epidermal growth factor receptor P00533 EGFR_HUMAN Homo sapiens 3 0.8321
Epidermal growth factor receptor P00533 EGFR_HUMAN Homo sapiens 3 0.8321
3',5'-cyclic-AMP phosphodiesterase 4D Q08499 PDE4D_HUMAN Homo sapiens 3 0.8268
3',5'-cyclic-AMP phosphodiesterase 4D Q08499 PDE4D_HUMAN Homo sapiens 3 0.8268
Peroxisome proliferator-activated receptor gamma P37231 PPARG_HUMAN Homo sapiens 4 0.8190
Peroxisome proliferator-activated receptor gamma P37231 PPARG_HUMAN Homo sapiens 4 0.8190
Epidermal growth factor receptor P00533 EGFR_HUMAN Homo sapiens 3 0.8158
Epidermal growth factor receptor P00533 EGFR_HUMAN Homo sapiens 3 0.8158
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform O02697 PK3CG_PIG Sus scrofa 5 0.8146
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform O02697 PK3CG_PIG Sus scrofa 5 0.8146
3',5'-cyclic-AMP phosphodiesterase 4D Q08499 PDE4D_HUMAN Homo sapiens 3 0.8101
3',5'-cyclic-AMP phosphodiesterase 4D Q08499 PDE4D_HUMAN Homo sapiens 3 0.8101
Cis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase Q46381 BPHB_COMTE Comamonas testosteroni 3 0.8029
Cis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase Q46381 BPHB_COMTE Comamonas testosteroni 3 0.8029
Casein kinase II subunit alpha P68400 CSK21_HUMAN Homo sapiens 3 0.8003
Casein kinase II subunit alpha P68400 CSK21_HUMAN Homo sapiens 3 0.8003
Serine/threonine-protein kinase toxin HipA P23874 HIPA_ECOLI Escherichia coli 3 0.8003
Serine/threonine-protein kinase toxin HipA P23874 HIPA_ECOLI Escherichia coli 3 0.8003
Epidermal growth factor receptor P00533 EGFR_HUMAN Homo sapiens 3 0.7992
Epidermal growth factor receptor P00533 EGFR_HUMAN Homo sapiens 3 0.7992
Ephrin type-B receptor 2 P54763 EPHB2_MOUSE Mus musculus 3 0.7980
Ephrin type-B receptor 2 P54763 EPHB2_MOUSE Mus musculus 3 0.7980
Fibroblast growth factor receptor 2 P21802 FGFR2_HUMAN Homo sapiens 3 0.7977
Fibroblast growth factor receptor 2 P21802 FGFR2_HUMAN Homo sapiens 3 0.7977
Genome polyprotein O92972 POLG_HCVJ4 Hepatitis C virus genotype 1b 3 0.7969
Genome polyprotein O92972 POLG_HCVJ4 Hepatitis C virus genotype 1b 3 0.7969
Epidermal growth factor receptor P00533 EGFR_HUMAN Homo sapiens 3 0.7886
Epidermal growth factor receptor P00533 EGFR_HUMAN Homo sapiens 3 0.7886
Serine/threonine-protein kinase 10 O94804 STK10_HUMAN Homo sapiens 3 0.7885
Serine/threonine-protein kinase 10 O94804 STK10_HUMAN Homo sapiens 3 0.7885
Fibroblast growth factor receptor 2 P21802 FGFR2_HUMAN Homo sapiens 3 0.7864
Fibroblast growth factor receptor 2 P21802 FGFR2_HUMAN Homo sapiens 3 0.7864
Alpha-ketoglutarate-dependent dioxygenase FTO Q9C0B1 FTO_HUMAN Homo sapiens 3 0.7858
Alpha-ketoglutarate-dependent dioxygenase FTO Q9C0B1 FTO_HUMAN Homo sapiens 3 0.7858
cGMP-specific 3',5'-cyclic phosphodiesterase O76074 PDE5A_HUMAN Homo sapiens 4 0.7855
cGMP-specific 3',5'-cyclic phosphodiesterase O76074 PDE5A_HUMAN Homo sapiens 4 0.7855
Mitogen-activated protein kinase kinase kinase 5 Q99683 M3K5_HUMAN Homo sapiens 3 0.7790
Mitogen-activated protein kinase kinase kinase 5 Q99683 M3K5_HUMAN Homo sapiens 3 0.7790
Serpin domain-containing protein H0ZQY2 H0ZQY2_TAEGU Taeniopygia guttata 3 0.7749
Serpin domain-containing protein H0ZQY2 H0ZQY2_TAEGU Taeniopygia guttata 3 0.7749
HTH-type transcriptional repressor PurR P0ACP7 PURR_ECOLI Escherichia coli 3 0.7665
HTH-type transcriptional repressor PurR P0ACP7 PURR_ECOLI Escherichia coli 3 0.7665
Polyprotein Q80J95 Q80J95_9CALI Murine norovirus 1 3 0.7648
Polyprotein Q80J95 Q80J95_9CALI Murine norovirus 1 3 0.7648
Heat shock protein HSP 90-beta P08238 HS90B_HUMAN Homo sapiens 3 0.7591
Heat shock protein HSP 90-beta P08238 HS90B_HUMAN Homo sapiens 3 0.7591
Death-associated protein kinase 1 P53355 DAPK1_HUMAN Homo sapiens 4 0.7570
Death-associated protein kinase 1 P53355 DAPK1_HUMAN Homo sapiens 4 0.7570
Chitinase A Q9AMP1 Q9AMP1_VIBHA Vibrio harveyi 2 0.7561
Chitinase A Q9AMP1 Q9AMP1_VIBHA Vibrio harveyi 2 0.7561
Chitinase A Q9AMP1 Q9AMP1_VIBHA Vibrio harveyi 2 0.7541
Chitinase A Q9AMP1 Q9AMP1_VIBHA Vibrio harveyi 2 0.7541
Death-associated protein kinase 1 P53355 DAPK1_HUMAN Homo sapiens 3 0.7537
Death-associated protein kinase 1 P53355 DAPK1_HUMAN Homo sapiens 3 0.7537
Serine/threonine-protein kinase 24 Q9Y6E0 STK24_HUMAN Homo sapiens 3 0.7527
Serine/threonine-protein kinase 24 Q9Y6E0 STK24_HUMAN Homo sapiens 3 0.7527
S-adenosylmethionine decarboxylase proenzyme P17707 DCAM_HUMAN Homo sapiens 4 0.7525
S-adenosylmethionine decarboxylase proenzyme P17707 DCAM_HUMAN Homo sapiens 4 0.7525
Lysozyme C II P11941 LYSC2_ONCMY Oncorhynchus mykiss 3 0.7496
Lysozyme C II P11941 LYSC2_ONCMY Oncorhynchus mykiss 3 0.7496
Lactotransferrin P24627 TRFL_BOVIN Bos taurus 2 0.7495
Lactotransferrin P24627 TRFL_BOVIN Bos taurus 2 0.7495
Tyrosine-protein kinase Lck P06239 LCK_HUMAN Homo sapiens 3 0.7489
Tyrosine-protein kinase Lck P06239 LCK_HUMAN Homo sapiens 3 0.7489
Aldo-keto reductase family 1 member B1 P15121 ALDR_HUMAN Homo sapiens 3 0.7471
Aldo-keto reductase family 1 member B1 P15121 ALDR_HUMAN Homo sapiens 3 0.7471
Aldos-2-ulose dehydratase P84193 AUD_PHACH Phanerodontia chrysosporium 3 0.7422
Aldos-2-ulose dehydratase P84193 AUD_PHACH Phanerodontia chrysosporium 3 0.7422
Bromodomain-containing protein 2 P25440 BRD2_HUMAN Homo sapiens 3 0.7409
Bromodomain-containing protein 2 P25440 BRD2_HUMAN Homo sapiens 3 0.7409
17-beta-hydroxysteroid dehydrogenase type 1 P14061 DHB1_HUMAN Homo sapiens 2 0.7396
17-beta-hydroxysteroid dehydrogenase type 1 P14061 DHB1_HUMAN Homo sapiens 2 0.7396
Nuclear receptor subfamily 4immunitygroup A member 1 P22736 NR4A1_HUMAN Homo sapiens 3 0.7389
Nuclear receptor subfamily 4immunitygroup A member 1 P22736 NR4A1_HUMAN Homo sapiens 3 0.7389
LIM domain kinase 1 P53667 LIMK1_HUMAN Homo sapiens 3 0.7374
LIM domain kinase 1 P53667 LIMK1_HUMAN Homo sapiens 3 0.7374
Poly [ADP-ribose] polymerase tankyrase-2 Q9H2K2 TNKS2_HUMAN Homo sapiens 4 0.7362
Poly [ADP-ribose] polymerase tankyrase-2 Q9H2K2 TNKS2_HUMAN Homo sapiens 4 0.7362
Proto-oncogene tyrosine-protein kinase Src P00523 SRC_CHICK Gallus gallus 3 0.7331
Proto-oncogene tyrosine-protein kinase Src P00523 SRC_CHICK Gallus gallus 3 0.7331
Polyribonucleotide nucleotidyltransferase A7ZS61 PNP_ECO24 Escherichia coli O139:H28 3 0.7317
Polyribonucleotide nucleotidyltransferase A7ZS61 PNP_ECO24 Escherichia coli O139:H28 3 0.7317
Mitogen-activated protein kinase 14 Q16539 MK14_HUMAN Homo sapiens 3 0.7313
Mitogen-activated protein kinase 14 Q16539 MK14_HUMAN Homo sapiens 3 0.7313
NAD-dependent protein deacetylase Q9WYW0 NPD_THEMA Thermotoga maritima 3 0.7299
NAD-dependent protein deacetylase Q9WYW0 NPD_THEMA Thermotoga maritima 3 0.7299
Poly [ADP-ribose] polymerase tankyrase-2 Q9H2K2 TNKS2_HUMAN Homo sapiens 4 0.7284
Poly [ADP-ribose] polymerase tankyrase-2 Q9H2K2 TNKS2_HUMAN Homo sapiens 4 0.7284
Heat shock protein HSP 90-alpha P07900 HS90A_HUMAN Homo sapiens 3 0.7267
Heat shock protein HSP 90-alpha P07900 HS90A_HUMAN Homo sapiens 3 0.7267
ATP-dependent molecular chaperone HSP82 P02829 HSP82_YEAST Saccharomyces cerevisiae 3 0.7263
ATP-dependent molecular chaperone HSP82 P02829 HSP82_YEAST Saccharomyces cerevisiae 3 0.7263
Poly [ADP-ribose] polymerase tankyrase-2 Q9H2K2 TNKS2_HUMAN Homo sapiens 5 0.7256
Poly [ADP-ribose] polymerase tankyrase-2 Q9H2K2 TNKS2_HUMAN Homo sapiens 5 0.7256
Beta-secretase 1 P56817 BACE1_HUMAN Homo sapiens 3 0.7245
Beta-secretase 1 P56817 BACE1_HUMAN Homo sapiens 3 0.7245
Poly [ADP-ribose] polymerase tankyrase-2 Q9H2K2 TNKS2_HUMAN Homo sapiens 4 0.7237
Poly [ADP-ribose] polymerase tankyrase-2 Q9H2K2 TNKS2_HUMAN Homo sapiens 4 0.7237
DNA mismatch repair protein Msh2 P43246 MSH2_HUMAN Homo sapiens 3 0.7231
DNA mismatch repair protein Msh2 P43246 MSH2_HUMAN Homo sapiens 3 0.7231
EbrA repressor Q79SH7 Q79SH7_STRLI Streptomyces lividans 3 0.7226
EbrA repressor Q79SH7 Q79SH7_STRLI Streptomyces lividans 3 0.7226
Cytosolic purine 5'-nucleotidase P49902 5NTC_HUMAN Homo sapiens 2 0.7219
Cytosolic purine 5'-nucleotidase P49902 5NTC_HUMAN Homo sapiens 2 0.7219
Serine/threonine-protein kinase pim-1 P11309 PIM1_HUMAN Homo sapiens 3 0.7202
Serine/threonine-protein kinase pim-1 P11309 PIM1_HUMAN Homo sapiens 3 0.7202
IOMT 3 Q06YR3 Q06YR3_MEDTR Medicago truncatula 3 0.7194
IOMT 3 Q06YR3 Q06YR3_MEDTR Medicago truncatula 3 0.7194
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A Q9Y233 PDE10_HUMAN Homo sapiens 3 0.7185
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A Q9Y233 PDE10_HUMAN Homo sapiens 3 0.7185
Biotin carboxylase P24182 ACCC_ECOLI Escherichia coli 3 0.7180
Biotin carboxylase P24182 ACCC_ECOLI Escherichia coli 3 0.7180
beta-glucosidase Q92AS9 Q92AS9_LISIN Listeria innocua serovar 6a 3 0.7178
Casein kinase II subunit alpha P28523 CSK2A_MAIZE Zea mays 4 0.7178
beta-glucosidase Q92AS9 Q92AS9_LISIN Listeria innocua serovar 6a 3 0.7178
Casein kinase II subunit alpha P28523 CSK2A_MAIZE Zea mays 4 0.7178
cGMP-specific 3',5'-cyclic phosphodiesterase O76074 PDE5A_HUMAN Homo sapiens 3 0.7172
Methyltransferase D0VX01 D0VX01_WSLV Wesselsbron virus 4 0.7172
cGMP-specific 3',5'-cyclic phosphodiesterase O76074 PDE5A_HUMAN Homo sapiens 3 0.7172
Methyltransferase D0VX01 D0VX01_WSLV Wesselsbron virus 4 0.7172
Methyltransferase D0VX01 D0VX01_WSLV Wesselsbron virus 3 0.7166
Methyltransferase D0VX01 D0VX01_WSLV Wesselsbron virus 3 0.7166
Peripheral plasma membrane protein CASK O14936 CSKP_HUMAN Homo sapiens 3 0.7163
Peripheral plasma membrane protein CASK O14936 CSKP_HUMAN Homo sapiens 3 0.7163
Serine/threonine-protein kinase Chk1 O14757 CHK1_HUMAN Homo sapiens 3 0.7153
Serine/threonine-protein kinase Chk1 O14757 CHK1_HUMAN Homo sapiens 3 0.7153
Type II methyltransferase M.TaqI P14385 MTTA_THEAQ Thermus aquaticus 3 0.7148
Type II methyltransferase M.TaqI P14385 MTTA_THEAQ Thermus aquaticus 3 0.7148
Hygromycin-B 4-O-kinase P00557 KHYB_ECOLX Escherichia coli 3 0.7137
Hygromycin-B 4-O-kinase P00557 KHYB_ECOLX Escherichia coli 3 0.7137
Threonine--tRNA ligase P0A8M3 SYT_ECOLI Escherichia coli 3 0.7118
Threonine--tRNA ligase P0A8M3 SYT_ECOLI Escherichia coli 3 0.7118
Putative S-adenosyl-L-methionine-dependent methyltransferase ML2640 Q9CCZ4 Y2640_MYCLE Mycobacterium leprae 3 0.7115
Putative S-adenosyl-L-methionine-dependent methyltransferase ML2640 Q9CCZ4 Y2640_MYCLE Mycobacterium leprae 3 0.7115
4-hydroxyphenylacetate 3-monooxygenase Q8YHT7 Q8YHT7_BRUME Brucella melitensis biotype 1 2 0.7103
4-hydroxyphenylacetate 3-monooxygenase Q8YHT7 Q8YHT7_BRUME Brucella melitensis biotype 1 2 0.7103
Glycylpeptide N-tetradecanoyltransferase A5K1A2 A5K1A2_PLAVS Plasmodium vivax 4 0.7086
Glycylpeptide N-tetradecanoyltransferase A5K1A2 A5K1A2_PLAVS Plasmodium vivax 4 0.7086
Hygromycin-B 4-O-kinase P00557 KHYB_ECOLX Escherichia coli 3 0.7078
Hygromycin-B 4-O-kinase P00557 KHYB_ECOLX Escherichia coli 3 0.7078
Epidermal growth factor receptor P00533 EGFR_HUMAN Homo sapiens 3 0.7076
Epidermal growth factor receptor P00533 EGFR_HUMAN Homo sapiens 3 0.7076
Cytochrome P450 S6BVH1 S6BVH1_RHOER Rhodococcus erythropolis 3 0.7056
Type II methyltransferase M.TaqI P14385 MTTA_THEAQ Thermus aquaticus 3 0.7056
Type II methyltransferase M.TaqI P14385 MTTA_THEAQ Thermus aquaticus 3 0.7056
Cytochrome P450 S6BVH1 S6BVH1_RHOER Rhodococcus erythropolis 3 0.7056
Lactoylglutathione lyase Q9CPU0 LGUL_MOUSE Mus musculus 3 0.7054
Lactoylglutathione lyase Q9CPU0 LGUL_MOUSE Mus musculus 3 0.7054
Acyl-coenzyme A synthetase ACSM2A, mitochondrial Q08AH3 ACS2A_HUMAN Homo sapiens 2 0.7044
Acyl-coenzyme A synthetase ACSM2A, mitochondrial Q08AH3 ACS2A_HUMAN Homo sapiens 2 0.7044
Neuropilin-1 O14786 NRP1_HUMAN Homo sapiens 3 0.7041
Neuropilin-1 O14786 NRP1_HUMAN Homo sapiens 3 0.7041
Nitric oxide synthase, inducible P29477 NOS2_MOUSE Mus musculus 4 0.7033
Nitric oxide synthase, inducible P29477 NOS2_MOUSE Mus musculus 4 0.7033
Anthocyanidin 3-O-glucosyltransferase UFGT P51094 UFOG_VITVI Vitis vinifera 4 0.7020
Anthocyanidin 3-O-glucosyltransferase UFGT P51094 UFOG_VITVI Vitis vinifera 4 0.7020
Cathepsin S P25774 CATS_HUMAN Homo sapiens 3 0.7018
Cathepsin S P25774 CATS_HUMAN Homo sapiens 3 0.7018
DNA mismatch repair protein MutS P23909 MUTS_ECOLI Escherichia coli 3 0.7016
DNA mismatch repair protein MutS P23909 MUTS_ECOLI Escherichia coli 3 0.7016
Genome polyprotein A0EKU1 A0EKU1_9FLAV Meaban virus 3 0.7015
Genome polyprotein A0EKU1 A0EKU1_9FLAV Meaban virus 3 0.7015
Poly [ADP-ribose] polymerase tankyrase-2 Q9H2K2 TNKS2_HUMAN Homo sapiens 4 0.7013
Poly [ADP-ribose] polymerase tankyrase-2 Q9H2K2 TNKS2_HUMAN Homo sapiens 4 0.7013
Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplastic Q43088 RBCMT_PEA Pisum sativum 3 0.7005
Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplastic Q43088 RBCMT_PEA Pisum sativum 3 0.7005

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