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Cocciferin D2
- Family: Plantae - Fagaceae
- Kingdom: Plantae
- Class: Tannin
Canonical Smiles | Oc1cc(C(=O)O[C@@H]2OC3COC(=O)c4cc(O)c(c(c4c4c(C(=O)OC3[C@@H]3[C@H]2OC(=O)c2cc(O)c(c(c2c2c(C(=O)O3)cc(c(c2O)O)O)O)O)cc(O)c(c4O)O)O)O)c(c(c1O)O)Oc1cc2C(=O)OC3[C@H](COC(=O)c4c(c2c(c1O)O)c(O)c(c(c4)O)O)OC(=O)c1cc(O)c(c(c1c1c2C(=O)O[C@@H]3[C@@H]3OC(=O)c4c([C@H]3O)c(O)c(c(c4c2c(c(c1O)O)O)O)O)O)O |
---|---|
InChI | InChI=1S/C82H52O52/c83-19-1-11-29(50(98)42(19)90)31-13(3-21(85)44(92)52(31)100)75(116)129-67-28(10-124-73(11)114)127-82(71-70(67)131-76(117)14-4-22(86)45(93)53(101)32(14)33-15(77(118)133-71)5-23(87)46(94)54(33)102)134-79(120)18-7-25(89)48(96)64(112)65(18)125-26-8-17-34(56(104)49(26)97)30-12(2-20(84)43(91)51(30)99)72(113)123-9-27-66(128-78(17)119)69-68-61(109)41-40(81(122)130-68)38(59(107)63(111)60(41)108)37-39(80(121)132-69)36(57(105)62(110)58(37)106)35-16(74(115)126-27)6-24(88)47(95)55(35)103/h1-8,27-28,61,66-71,82-112H,9-10H2/t27-,28?,61+,66?,67?,68+,69-,70+,71+,82-/m0/s1 |
InChIKey | BMTRLZLCNOUQLK-XGGSKMECSA-N |
Formula | C82H52O52 |
HBA | 52 |
HBD | 30 |
MW | 1869.27 |
Rotatable Bonds | 4 |
TPSA | 888.36 |
LogP | 3.37 |
Number Rings | 18 |
Number Aromatic Rings | 10 |
Heavy Atom Count | 134 |
Formal Charge | 0 |
Fraction CSP3 | 0.15 |
Exact Mass | 1868.14 |
Number of Lipinski Rule Violations | 3 |
# | Species | Family | Kingdom | NCBI Taxonomy ID |
---|---|---|---|---|
1 | Quercus coccifera | Fagaceae | Plantae | 58335 |
Showing of synonyms
Cocciferin D2
Pubchem:
162866420
No compound-protein relationship available.
No scaffolds available.
Antimicrobial
Absorption
- Caco-2 (logPapp)
- -6.04
- Human Oral Bioavailability 20%
- Bioavailable
- Human Intestinal Absorption
- Absorbed
- Madin-Darby Canine Kidney
- 1280520710179038000000000000000000
- Human Oral Bioavailability 50%
- Non-Bioavailable
- P-Glycoprotein Inhibitor
- Non-Inhibitor
- P-Glycoprotein Substrate
- Non-Substrate
- Skin Permeability
- 167349060151992500000000000000000000
Distribution
- Blood-Brain Barrier (CNS)
- -
- Blood-Brain Barrier
- Non-Penetrable
- Fraction Unbound (Human)
- -0.57
- Plasma Protein Binding
- 89.29
- Steady State Volume of Distribution
- -
Metabolism
- Breast Cancer Resistance Protein
- Non-Inhibitor
- CYP 1A2 Inhibitor
- Non-Inhibitor
- CYP 1A2 Substrate
- Non-Substrate
- CYP 2C19 Inhibitor
- Non-Inhibitor
- CYP 2C19 Substrate
- Non-Substrate
- CYP 2C9 Inhibitor
- Non-Inhibitor
- CYP 2C9 Substrate
- Non-Substrate
- CYP 2D6 Inhibitor
- Non-Inhibitor
- CYP 2D6 Substrate
- Non-Substrate
- CYP 3A4 Inhibitor
- Non-Inhibitor
- CYP 3A4 Substrate
- Non-Substrate
- OATP1B1
- Non-Inhibitor
- OATP1B3
- Non-Inhibitor
Excretion
- Clearance
- 8.91
- Organic Cation Transporter 2
- Non-Inhibitor
- Half-Life of Drug
- -
Toxicity
- AMES Mutagenesis
- Safe
- Avian
- Toxic
- Bee
- Safe
- Bioconcentration Factor
- -3892159955948552000000000000000000
- Biodegradation
- Toxic
- Carcinogenesis
- Safe
- Crustacean
- Toxic
- Liver Injury I (DILI)
- Toxic
- Eye Corrosion
- Safe
- Eye Irritation
- Safe
- Maximum Tolerated Dose
- -1589214804605392400000000000
- Liver Injury II
- Toxic
- hERG Blockers
- Toxic
- Daphnia Maga
- 4.05
- Micronucleos
- Toxic
- NR-AhR
- Safe
- NR-AR
- Safe
- NR-AR-LBD
- Toxic
- NR-Aromatase
- Safe
- NR-ER
- Safe
- NR-ER-LBD
- Safe
- NR-GR
- Safe
- NR-PPAR-gamma
- Toxic
- NR-TR
- Toxic
- T. Pyriformis
- -Infinity
- Rat (Acute)
- 244946056074996250000000
- Rat (Chronic Oral)
- 651475338009596700000000000000
- Fathead Minnow
- 383395035371025900000000000000000000
- Respiratory Disease
- Toxic
- Skin Sensitisation
- Safe
- SR-ARE
- Toxic
- SR-ATAD5
- Toxic
- SR-HSE
- Safe
- SR-MMP
- Toxic
- SR-p53
- Toxic
General Properties
- Boiling Point
- 34161256870921968000000000000000000000
- Hydration Free Energy
- -2.92
- Log(D) at pH=7.4
- -18990251417046045000000000000000
- Log(P)
- -2210689389062290000000000000
- Log S
- -13.58
- Log(Vapor Pressure)
- -1124912799154820400000000000000000000
- Melting Point
- -341820687044740600000000000000
- pKa Acid
- -8196764625107188000000000000000000
- pKa Basic
- -65942726106406125000000000000000
No predicted protein targets found for this compound.