4-(2-formyl-5-hydroxymethylpyrrol-1-yl) butyric acid - Compound Card

4-(2-formyl-5-hydroxymethylpyrrol-1-yl) butyric acid

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4-(2-formyl-5-hydroxymethylpyrrol-1-yl) butyric acid

Structure
Zoomed Structure
  • Family: Iridaceae
  • Kingdom: Plantae
  • Class: Pyrrole Derivative
Canonical Smiles OCc1ccc(n1CCCC(=O)O)C=O
InChI InChI=1S/C10H13NO4/c12-6-8-3-4-9(7-13)11(8)5-1-2-10(14)15/h3-4,6,13H,1-2,5,7H2,(H,14,15)
InChIKey WNNGLHOQCHCQFK-UHFFFAOYSA-N
Formula C10H13NO4
HBA 4
HBD 2
MW 211.22
Rotatable Bonds 6
TPSA 79.53
LogP 0.66
Number Rings 1
Number Aromatic Rings 1
Heavy Atom Count 15
Formal Charge 0
Fraction CSP3 0.4
Exact Mass 211.08
Number of Lipinski Rule Violations 0
# Species Family Kingdom NCBI Taxonomy ID
1 Iris spuria Iridaceae Plantae 93026

Showing of synonyms

  • Farag SF, Kimura Y, et al. (2009). New isoflavone glycosides from Iris spuria L. (Calizona) cultivated in Egypt. Journal of Natural Medicines,2009,63(1),91-95. [View] [PubMed]
Pubchem: 10198218
Nmrshiftdb2: 60030879

No compound-protein relationship available.

Structure

SMILES: c1cc[nH]c1

Level: 0

Mol. Weight: 67.09 g/mol

Antiviral

Absorption

Caco-2 (logPapp)
-4.82
Human Oral Bioavailability 20%
Bioavailable
Human Intestinal Absorption
Absorbed
Madin-Darby Canine Kidney
-4.52
Human Oral Bioavailability 50%
Bioavailable
P-Glycoprotein Inhibitor
Non-Inhibitor
P-Glycoprotein Substrate
Non-Substrate
Skin Permeability
-3.69

Distribution

Blood-Brain Barrier (CNS)
-
Blood-Brain Barrier
Non-Penetrable
Fraction Unbound (Human)
0.23
Plasma Protein Binding
9.76
Steady State Volume of Distribution
-

Metabolism

Breast Cancer Resistance Protein
Non-Inhibitor
CYP 1A2 Inhibitor
Non-Inhibitor
CYP 1A2 Substrate
Non-Substrate
CYP 2C19 Inhibitor
Non-Inhibitor
CYP 2C19 Substrate
Non-Substrate
CYP 2C9 Inhibitor
Non-Inhibitor
CYP 2C9 Substrate
Substrate
CYP 2D6 Inhibitor
Non-Inhibitor
CYP 2D6 Substrate
Non-Substrate
CYP 3A4 Inhibitor
Non-Inhibitor
CYP 3A4 Substrate
Non-Substrate
OATP1B1
Non-Inhibitor
OATP1B3
Non-Inhibitor

Excretion

Clearance
4.64
Organic Cation Transporter 2
Non-Inhibitor
Half-Life of Drug
-

Toxicity

AMES Mutagenesis
Toxic
Avian
Safe
Bee
Safe
Bioconcentration Factor
-1.05
Biodegradation
Toxic
Carcinogenesis
Safe
Crustacean
Safe
Liver Injury I (DILI)
Safe
Eye Corrosion
Safe
Eye Irritation
Toxic
Maximum Tolerated Dose
0.86
Liver Injury II
Safe
hERG Blockers
Safe
Daphnia Maga
3.12
Micronucleos
Toxic
NR-AhR
Safe
NR-AR
Safe
NR-AR-LBD
Safe
NR-Aromatase
Safe
NR-ER
Safe
NR-ER-LBD
Safe
NR-GR
Safe
NR-PPAR-gamma
Safe
NR-TR
Safe
T. Pyriformis
2.59
Rat (Acute)
1.42
Rat (Chronic Oral)
1.96
Fathead Minnow
3.87
Respiratory Disease
Safe
Skin Sensitisation
Toxic
SR-ARE
Safe
SR-ATAD5
Safe
SR-HSE
Safe
SR-MMP
Safe
SR-p53
Safe

General Properties

Boiling Point
358.62
Hydration Free Energy
-9.38
Log(D) at pH=7.4
-1.5
Log(P)
0.16
Log S
-1.11
Log(Vapor Pressure)
-7.43
Melting Point
139.98
pKa Acid
5.22
pKa Basic
6.6
Protein Name UniProt ID Entry Name Species #Pharmacophore Points Probability (0.7 ≤ Tversky Score ≤ 1.0)
Inosine-5'-monophosphate dehydrogenase P50097 IMDH_TRIFO Tritrichomonas foetus 3 0.9678
Inosine-5'-monophosphate dehydrogenase P50097 IMDH_TRIFO Tritrichomonas foetus 3 0.9678
D-alanyl-D-alanine carboxypeptidase P15555 DAC_STRSR Streptomyces sp 3 0.9527
D-alanyl-D-alanine carboxypeptidase P15555 DAC_STRSR Streptomyces sp 3 0.9527
Norsolorinic acid synthase Q12053 AFLC_ASPPU Aspergillus parasiticus 3 0.9521
Norsolorinic acid synthase Q12053 AFLC_ASPPU Aspergillus parasiticus 3 0.9521
Peptide deformylase 1B, chloroplastic/mitochondrial Q9FUZ2 DEF1B_ARATH Arabidopsis thaliana 3 0.9430
Peptide deformylase 1B, chloroplastic/mitochondrial Q9FUZ2 DEF1B_ARATH Arabidopsis thaliana 3 0.9430
NADPH dehydrogenase 1 Q02899 OYE1_SACPS Saccharomyces pastorianus 3 0.9201
NADPH dehydrogenase 1 Q02899 OYE1_SACPS Saccharomyces pastorianus 3 0.9201
Tetracycline repressor protein class H P51561 TETR8_PASMD Pasteurella multocida 3 0.9188
Tetracycline repressor protein class H P51561 TETR8_PASMD Pasteurella multocida 3 0.9188
Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial Q8N5Z0 AADAT_HUMAN Homo sapiens 3 0.9142
Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial Q8N5Z0 AADAT_HUMAN Homo sapiens 3 0.9142
Aldo-keto reductase family 1 member B1 P15121 ALDR_HUMAN Homo sapiens 3 0.9138
Aldo-keto reductase family 1 member B1 P15121 ALDR_HUMAN Homo sapiens 3 0.9138
Polymerase basic protein 2 P31345 PB2_I75A3 Influenza A virus 3 0.9107
Polymerase basic protein 2 P31345 PB2_I75A3 Influenza A virus 3 0.9107
Beta-galactoside-specific lectin 4 Q6ITZ3 ML4_VISAL Viscum album 3 0.9051
Beta-galactoside-specific lectin 4 Q6ITZ3 ML4_VISAL Viscum album 3 0.9051
Flavoredoxin Q72HI0 Q72HI0_THET2 Thermus thermophilus 3 0.9021
Flavoredoxin Q72HI0 Q72HI0_THET2 Thermus thermophilus 3 0.9021
NAD-capped RNA hydrolase NudC P32664 NUDC_ECOLI Escherichia coli 3 0.9019
NAD-capped RNA hydrolase NudC P32664 NUDC_ECOLI Escherichia coli 3 0.9019
Basic phospholipase A2 VRV-PL-VIIIa P59071 PA2B8_DABRR Daboia russelii 3 0.9006
Basic phospholipase A2 VRV-PL-VIIIa P59071 PA2B8_DABRR Daboia russelii 3 0.9006
Heat shock protein HSP 90-alpha P07900 HS90A_HUMAN Homo sapiens 3 0.8996
Heat shock protein HSP 90-alpha P07900 HS90A_HUMAN Homo sapiens 3 0.8996
Acidic phospholipase A2 3 P60045 PA2A3_NAJSG Naja sagittifera 3 0.8957
Acidic phospholipase A2 3 P60045 PA2A3_NAJSG Naja sagittifera 3 0.8957
Heat shock protein HSP 90-alpha P07900 HS90A_HUMAN Homo sapiens 3 0.8946
Heat shock protein HSP 90-alpha P07900 HS90A_HUMAN Homo sapiens 3 0.8946
Beta-1 adrenergic receptor P07700 ADRB1_MELGA Meleagris gallopavo 3 0.8930
Beta-1 adrenergic receptor P07700 ADRB1_MELGA Meleagris gallopavo 3 0.8930
Endoplasmin P41148 ENPL_CANLF Canis lupus familiaris 3 0.8914
Endoplasmin P41148 ENPL_CANLF Canis lupus familiaris 3 0.8914
ATP-dependent molecular chaperone HSP82 P02829 HSP82_YEAST Saccharomyces cerevisiae 3 0.8880
ATP-dependent molecular chaperone HSP82 P02829 HSP82_YEAST Saccharomyces cerevisiae 3 0.8880
Biflaviolin synthase CYP158A2 Q9FCA6 C1582_STRCO Streptomyces coelicolor / M145) 3 0.8859
Biflaviolin synthase CYP158A2 Q9FCA6 C1582_STRCO Streptomyces coelicolor / M145) 3 0.8859
ATP-dependent molecular chaperone HSP82 P02829 HSP82_YEAST Saccharomyces cerevisiae 3 0.8802
ATP-dependent molecular chaperone HSP82 P02829 HSP82_YEAST Saccharomyces cerevisiae 3 0.8802
Biflaviolin synthase CYP158A2 Q9FCA6 C1582_STRCO Streptomyces coelicolor / M145) 3 0.8800
Biflaviolin synthase CYP158A2 Q9FCA6 C1582_STRCO Streptomyces coelicolor / M145) 3 0.8800
Aromatic-amino-acid aminotransferase P95468 TYRB_PARDE Paracoccus denitrificans 3 0.8762
Aromatic-amino-acid aminotransferase P95468 TYRB_PARDE Paracoccus denitrificans 3 0.8762
Pantothenate synthetase P9WIL4 PANC_MYCTO Mycobacterium tuberculosis 3 0.8746
Pantothenate synthetase P9WIL4 PANC_MYCTO Mycobacterium tuberculosis 3 0.8746
ATP-dependent molecular chaperone HSP82 P02829 HSP82_YEAST Saccharomyces cerevisiae 3 0.8728
ATP-dependent molecular chaperone HSP82 P02829 HSP82_YEAST Saccharomyces cerevisiae 3 0.8728
Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase Q9TQS6 DHDH_MACFA Macaca fascicularis 3 0.8726
Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase Q9TQS6 DHDH_MACFA Macaca fascicularis 3 0.8726
LysR-type regulatory protein Q7WT50 Q7WT50_9BURK Burkholderia sp. DNT 3 0.8695
LysR-type regulatory protein Q7WT50 Q7WT50_9BURK Burkholderia sp. DNT 3 0.8695
4-diphosphocytidyl-2-C-methyl-D-erythritol kinase O67060 ISPE_AQUAE Aquifex aeolicus 3 0.8684
4-diphosphocytidyl-2-C-methyl-D-erythritol kinase O67060 ISPE_AQUAE Aquifex aeolicus 3 0.8684
Kynurenine--oxoglutarate transaminase 1 Q16773 KAT1_HUMAN Homo sapiens 3 0.8611
Kynurenine--oxoglutarate transaminase 1 Q16773 KAT1_HUMAN Homo sapiens 3 0.8611
Fructose-1,6-bisphosphatase 1 P09467 F16P1_HUMAN Homo sapiens 3 0.8524
Fructose-1,6-bisphosphatase 1 P09467 F16P1_HUMAN Homo sapiens 3 0.8524
Branched-chain-amino-acid aminotransferase, mitochondrial O15382 BCAT2_HUMAN Homo sapiens 3 0.8481
Branched-chain-amino-acid aminotransferase, mitochondrial O15382 BCAT2_HUMAN Homo sapiens 3 0.8481
Carbonic anhydrase 2 P00918 CAH2_HUMAN Homo sapiens 3 0.8406
Carbonic anhydrase 2 P00918 CAH2_HUMAN Homo sapiens 3 0.8406
Tryptophan synthase alpha chain P00929 TRPA_SALTY Salmonella typhimurium 3 0.8395
Tryptophan synthase alpha chain P00929 TRPA_SALTY Salmonella typhimurium 3 0.8395
Serpin domain-containing protein H0ZQY2 H0ZQY2_TAEGU Taeniopygia guttata 3 0.8393
Serpin domain-containing protein H0ZQY2 H0ZQY2_TAEGU Taeniopygia guttata 3 0.8393
Queuine tRNA-ribosyltransferase P28720 TGT_ZYMMO Zymomonas mobilis subsp. mobilis 3 0.8386
Queuine tRNA-ribosyltransferase P28720 TGT_ZYMMO Zymomonas mobilis subsp. mobilis 3 0.8386
Biflaviolin synthase CYP158A1 Q9KZF5 C1581_STRCO Streptomyces coelicolor / M145) 3 0.8359
Biflaviolin synthase CYP158A1 Q9KZF5 C1581_STRCO Streptomyces coelicolor / M145) 3 0.8359
S-norcoclaurine synthase Q67A25 NCS_THLFG Thalictrum flavum subsp. glaucum 3 0.8347
S-norcoclaurine synthase Q67A25 NCS_THLFG Thalictrum flavum subsp. glaucum 3 0.8347
Polymerase acidic protein C3W5S0 C3W5S0_I09A0 Influenza A virus 3 0.8340
Polymerase acidic protein C3W5S0 C3W5S0_I09A0 Influenza A virus 3 0.8340
Isocitrate/homoisocitrate dehydrogenase Q5SIJ1 HICDH_THET8 Thermus thermophilus 3 0.8329
Isocitrate/homoisocitrate dehydrogenase Q5SIJ1 HICDH_THET8 Thermus thermophilus 3 0.8329
Soluble cytochrome b562 P0ABE7 C562_ECOLX Escherichia coli 3 0.8307
Soluble cytochrome b562 P0ABE7 C562_ECOLX Escherichia coli 3 0.8307
Thermolysin P00800 THER_BACTH Bacillus thermoproteolyticus 3 0.8288
Thermolysin P00800 THER_BACTH Bacillus thermoproteolyticus 3 0.8288
Carbonic anhydrase 1 P00915 CAH1_HUMAN Homo sapiens 3 0.8284
Carbonic anhydrase 1 P00915 CAH1_HUMAN Homo sapiens 3 0.8284
Gentisate 1,2-dioxygenase Q67FT0 Q67FT0_PSESE Pseudaminobacter salicylatoxidans 3 0.8243
Gentisate 1,2-dioxygenase Q67FT0 Q67FT0_PSESE Pseudaminobacter salicylatoxidans 3 0.8243
Polymerase acidic protein Q5EP34 Q5EP34_9INFA Influenza A virus 3 0.8181
Polymerase acidic protein Q5EP34 Q5EP34_9INFA Influenza A virus 3 0.8181
Streptavidin P22629 SAV_STRAV Streptomyces avidinii 3 0.8133
Streptavidin P22629 SAV_STRAV Streptomyces avidinii 3 0.8133
ADP-ribosylation factor 1 P84080 ARF1_BOVIN Bos taurus 3 0.8129
ADP-ribosylation factor 1 P84080 ARF1_BOVIN Bos taurus 3 0.8129
rRNA methylase Q8DSS3 Q8DSS3_STRMU Streptococcus mutans serotype c 2 0.8126
rRNA methylase Q8DSS3 Q8DSS3_STRMU Streptococcus mutans serotype c 2 0.8126
3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase P19992 HSD_STREX Streptomyces exfoliatus 3 0.8076
3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase P19992 HSD_STREX Streptomyces exfoliatus 3 0.8076
NADPH-dependent 7-cyano-7-deazaguanine reductase Q9KTK0 QUEF_VIBCH Vibrio cholerae serotype O1 3 0.8062
NADPH-dependent 7-cyano-7-deazaguanine reductase Q9KTK0 QUEF_VIBCH Vibrio cholerae serotype O1 3 0.8062
L-lactate dehydrogenase A chain P04642 LDHA_RAT Rattus norvegicus 3 0.8060
L-lactate dehydrogenase A chain P04642 LDHA_RAT Rattus norvegicus 3 0.8060
Mitogen-activated protein kinase 14 Q16539 MK14_HUMAN Homo sapiens 3 0.8026
Mitogen-activated protein kinase 14 Q16539 MK14_HUMAN Homo sapiens 3 0.8026
2',3'-cyclic-nucleotide 3'-phosphodiesterase P16330 CN37_MOUSE Mus musculus 3 0.8009
2',3'-cyclic-nucleotide 3'-phosphodiesterase P16330 CN37_MOUSE Mus musculus 3 0.8009
Streptavidin P22629 SAV_STRAV Streptomyces avidinii 3 0.7972
Streptavidin P22629 SAV_STRAV Streptomyces avidinii 3 0.7972
HTH-type transcriptional repressor PurR P0ACP7 PURR_ECOLI Escherichia coli 3 0.7935
HTH-type transcriptional repressor PurR P0ACP7 PURR_ECOLI Escherichia coli 3 0.7935
Cyclin-dependent kinase 2 P24941 CDK2_HUMAN Homo sapiens 3 0.7917
Cyclin-dependent kinase 2 P24941 CDK2_HUMAN Homo sapiens 3 0.7917
Major NAD(P)H-flavin oxidoreductase P46072 FRA1_ALIFS Aliivibrio fischeri 3 0.7915
Major NAD(P)H-flavin oxidoreductase P46072 FRA1_ALIFS Aliivibrio fischeri 3 0.7915
Heat shock protein HSP 90-alpha P07900 HS90A_HUMAN Homo sapiens 3 0.7909
Heat shock protein HSP 90-alpha P07900 HS90A_HUMAN Homo sapiens 3 0.7909
Endoplasmin P41148 ENPL_CANLF Canis lupus familiaris 3 0.7904
Endoplasmin P41148 ENPL_CANLF Canis lupus familiaris 3 0.7904
NAD(P)H-hydrate epimerase Q8K4Z3 NNRE_MOUSE Mus musculus 3 0.7898
NAD(P)H-hydrate epimerase Q8K4Z3 NNRE_MOUSE Mus musculus 3 0.7898
Chorismate mutase AroH P19080 AROH_BACSU Bacillus subtilis 3 0.7881
Chorismate mutase AroH P19080 AROH_BACSU Bacillus subtilis 3 0.7881
Metallo-beta-lactamase type 2 P26918 BLAB_AERHY Aeromonas hydrophila 3 0.7877
Metallo-beta-lactamase type 2 P26918 BLAB_AERHY Aeromonas hydrophila 3 0.7877
L-lactate dehydrogenase A chain P04642 LDHA_RAT Rattus norvegicus 3 0.7864
L-lactate dehydrogenase A chain P04642 LDHA_RAT Rattus norvegicus 3 0.7864
Inosine-5'-monophosphate dehydrogenase P50097 IMDH_TRIFO Tritrichomonas foetus 3 0.7859
Inosine-5'-monophosphate dehydrogenase P50097 IMDH_TRIFO Tritrichomonas foetus 3 0.7859
Xanthine dehydrogenase/oxidase P22985 XDH_RAT Rattus norvegicus 3 0.7857
Xanthine dehydrogenase/oxidase P22985 XDH_RAT Rattus norvegicus 3 0.7857
Aromatic-amino-acid aminotransferase P95468 TYRB_PARDE Paracoccus denitrificans 3 0.7853
Aromatic-amino-acid aminotransferase P95468 TYRB_PARDE Paracoccus denitrificans 3 0.7853
SKP1-like protein 1A Q39255 SKP1A_ARATH Arabidopsis thaliana 3 0.7851
SKP1-like protein 1A Q39255 SKP1A_ARATH Arabidopsis thaliana 3 0.7851
3-hydroxyanthranilate 3,4-dioxygenase Q1LCS4 3HAO_CUPMC Cupriavidus metallidurans 3 0.7836
3-hydroxyanthranilate 3,4-dioxygenase Q1LCS4 3HAO_CUPMC Cupriavidus metallidurans 3 0.7836
Carbonic anhydrase 1 P00915 CAH1_HUMAN Homo sapiens 3 0.7826
Carbonic anhydrase 1 P00915 CAH1_HUMAN Homo sapiens 3 0.7826
Ras-related protein Ral-B P11234 RALB_HUMAN Homo sapiens 3 0.7801
Ras-related protein Ral-B P11234 RALB_HUMAN Homo sapiens 3 0.7801
Type IV / VI secretion system DotU domain-containing protein Q9KN50 Q9KN50_VIBCH Vibrio cholerae serotype O1 2 0.7764
Type IV / VI secretion system DotU domain-containing protein Q9KN50 Q9KN50_VIBCH Vibrio cholerae serotype O1 2 0.7764
HTH-type transcriptional repressor PurR P0ACP7 PURR_ECOLI Escherichia coli 3 0.7752
HTH-type transcriptional repressor PurR P0ACP7 PURR_ECOLI Escherichia coli 3 0.7752
MAP kinase-activated protein kinase 2 P49137 MAPK2_HUMAN Homo sapiens 3 0.7734
MAP kinase-activated protein kinase 2 P49137 MAPK2_HUMAN Homo sapiens 3 0.7734
ATP-dependent molecular chaperone HSP82 P02829 HSP82_YEAST Saccharomyces cerevisiae 3 0.7729
ATP-dependent molecular chaperone HSP82 P02829 HSP82_YEAST Saccharomyces cerevisiae 3 0.7729
Pancreatic alpha-amylase P04746 AMYP_HUMAN Homo sapiens 2 0.7708
Pancreatic alpha-amylase P04746 AMYP_HUMAN Homo sapiens 2 0.7708
VioE domain-containing protein Q7NSZ5 Q7NSZ5_CHRVO Chromobacterium violaceum 3 0.7678
VioE domain-containing protein Q7NSZ5 Q7NSZ5_CHRVO Chromobacterium violaceum 3 0.7678
Streptavidin P22629 SAV_STRAV Streptomyces avidinii 3 0.7653
Streptavidin P22629 SAV_STRAV Streptomyces avidinii 3 0.7653
Beta-galactoside alpha-2,6-sialyltransferase 1 P15907 SIAT1_HUMAN Homo sapiens 3 0.7650
Beta-galactoside alpha-2,6-sialyltransferase 1 P15907 SIAT1_HUMAN Homo sapiens 3 0.7650
Anthranilate phosphoribosyltransferase P9WFX5 TRPD_MYCTU Mycobacterium tuberculosis 3 0.7648
Anthranilate phosphoribosyltransferase P9WFX5 TRPD_MYCTU Mycobacterium tuberculosis 3 0.7648
Class 10 plant pathogenesis-related protein 2B Q9LLQ2 P102B_LUPLU Lupinus luteus 2 0.7646
Class 10 plant pathogenesis-related protein 2B Q9LLQ2 P102B_LUPLU Lupinus luteus 2 0.7646
Dihydropteroate synthase Q81VW8 Q81VW8_BACAN Bacillus anthracis 3 0.7635
Dihydropteroate synthase Q81VW8 Q81VW8_BACAN Bacillus anthracis 3 0.7635
D-aminoacyl-tRNA deacylase Q8IIS0 DTD_PLAF7 Plasmodium falciparum 3 0.7630
D-aminoacyl-tRNA deacylase Q8IIS0 DTD_PLAF7 Plasmodium falciparum 3 0.7630
Xylose isomerase P24300 XYLA_STRRU Streptomyces rubiginosus 3 0.7612
Xylose isomerase P24300 XYLA_STRRU Streptomyces rubiginosus 3 0.7612
Stromelysin-1 P08254 MMP3_HUMAN Homo sapiens 3 0.7606
Stromelysin-1 P08254 MMP3_HUMAN Homo sapiens 3 0.7606
Thiazole tautomerase P25053 TENI_BACSU Bacillus subtilis 3 0.7604
Thiazole tautomerase P25053 TENI_BACSU Bacillus subtilis 3 0.7604
Glycogen synthase kinase-3 beta P49841 GSK3B_HUMAN Homo sapiens 2 0.7594
Glycogen synthase kinase-3 beta P49841 GSK3B_HUMAN Homo sapiens 2 0.7594
Benzoylformate decarboxylase P20906 MDLC_PSEPU Pseudomonas putida 3 0.7590
Benzoylformate decarboxylase P20906 MDLC_PSEPU Pseudomonas putida 3 0.7590
Cysteine synthase 1 P47998 CYSK1_ARATH Arabidopsis thaliana 3 0.7581
Cysteine synthase 1 P47998 CYSK1_ARATH Arabidopsis thaliana 3 0.7581
Anthranilate phosphoribosyltransferase P00500 TRPD_ACIAD Acinetobacter baylyi 3 0.7573
Anthranilate phosphoribosyltransferase P00500 TRPD_ACIAD Acinetobacter baylyi 3 0.7573
Cyclin-dependent kinase 2 P24941 CDK2_HUMAN Homo sapiens 3 0.7570
Cyclin-dependent kinase 2 P24941 CDK2_HUMAN Homo sapiens 3 0.7570
4-hydroxyphenylacetate 3-monooxygenase, reductase component Q5SJP7 HPAC_THET8 Thermus thermophilus 3 0.7569
4-hydroxyphenylacetate 3-monooxygenase, reductase component Q5SJP7 HPAC_THET8 Thermus thermophilus 3 0.7569
Phospholipase A2 P00593 PA21B_BOVIN Bos taurus 3 0.7568
Phospholipase A2 P00593 PA21B_BOVIN Bos taurus 3 0.7568
cGMP-dependent 3',5'-cyclic phosphodiesterase O00408 PDE2A_HUMAN Homo sapiens 3 0.7562
cGMP-dependent 3',5'-cyclic phosphodiesterase O00408 PDE2A_HUMAN Homo sapiens 3 0.7562
SKP1-like protein 1A Q39255 SKP1A_ARATH Arabidopsis thaliana 3 0.7558
SKP1-like protein 1A Q39255 SKP1A_ARATH Arabidopsis thaliana 3 0.7558
cGMP-dependent protein kinase 1 P00516 KGP1_BOVIN Bos taurus 3 0.7554
cGMP-dependent protein kinase 1 P00516 KGP1_BOVIN Bos taurus 3 0.7554
Phosphotriesterase Q5KZU5 Q5KZU5_GEOKA Geobacillus kaustophilus 3 0.7548
Phosphotriesterase Q5KZU5 Q5KZU5_GEOKA Geobacillus kaustophilus 3 0.7548
Toxoflavin degrading enzyme E3SET7 E3SET7_PAEPO Paenibacillus polymyxa 3 0.7542
Toxoflavin degrading enzyme E3SET7 E3SET7_PAEPO Paenibacillus polymyxa 3 0.7542
N-acetyltransferase domain-containing protein Q9HV14 Q9HV14_PSEAE Pseudomonas aeruginosa 2 0.7528
N-acetyltransferase domain-containing protein Q9HV14 Q9HV14_PSEAE Pseudomonas aeruginosa 2 0.7528
Anthranilate phosphoribosyltransferase P50384 TRPD_SACS2 Saccharolobus solfataricus 3 0.7522
Anthranilate phosphoribosyltransferase P50384 TRPD_SACS2 Saccharolobus solfataricus 3 0.7522
Orotidine 5'-phosphate decarboxylase Q5L0U0 PYRF_GEOKA Geobacillus kaustophilus 3 0.7519
Orotidine 5'-phosphate decarboxylase Q5L0U0 PYRF_GEOKA Geobacillus kaustophilus 3 0.7519
Eukaryotic translation initiation factor 4E type 3 Q9DBB5 IF4E3_MOUSE Mus musculus 3 0.7497
Eukaryotic translation initiation factor 4E type 3 Q9DBB5 IF4E3_MOUSE Mus musculus 3 0.7497
CCA-adding enzyme O28126 CCA_ARCFU Archaeoglobus fulgidus 2 0.7492
CCA-adding enzyme O28126 CCA_ARCFU Archaeoglobus fulgidus 2 0.7492
Tannase B3Y018 B3Y018_LACPN Lactiplantibacillus plantarum 3 0.7475
Tannase B3Y018 B3Y018_LACPN Lactiplantibacillus plantarum 3 0.7475
Nuclear receptor subfamily 4immunitygroup A member 1 P22736 NR4A1_HUMAN Homo sapiens 2 0.7461
Nuclear receptor subfamily 4immunitygroup A member 1 P22736 NR4A1_HUMAN Homo sapiens 2 0.7461
Lactotransferrin P24627 TRFL_BOVIN Bos taurus 2 0.7459
Lactotransferrin P24627 TRFL_BOVIN Bos taurus 2 0.7459
ADP compounds hydrolase NudE P45799 NUDE_ECOLI Escherichia coli 2 0.7458
ADP compounds hydrolase NudE P45799 NUDE_ECOLI Escherichia coli 2 0.7458
HTH-type transcriptional repressor PurR P0ACP7 PURR_ECOLI Escherichia coli 3 0.7451
HTH-type transcriptional repressor PurR P0ACP7 PURR_ECOLI Escherichia coli 3 0.7451
Nucleoside diphosphate kinase A 2 P52175 NDKA2_BOVIN Bos taurus 3 0.7441
Nucleoside diphosphate kinase A 2 P52175 NDKA2_BOVIN Bos taurus 3 0.7441
Malate dehydrogenase P10584 MDH_THETH Thermus thermophilus 3 0.7438
Malate dehydrogenase P10584 MDH_THETH Thermus thermophilus 3 0.7438
Serine/threonine-protein kinase SKY1 Q03656 SKY1_YEAST Saccharomyces cerevisiae 2 0.7421
Serine/threonine-protein kinase SKY1 Q03656 SKY1_YEAST Saccharomyces cerevisiae 2 0.7421
Cysteine desulfurase IscS 2 O29689 ISCS2_ARCFU Archaeoglobus fulgidus 3 0.7414
Cysteine desulfurase IscS 2 O29689 ISCS2_ARCFU Archaeoglobus fulgidus 3 0.7414
Basic phospholipase A2 VRV-PL-VIIIa P59071 PA2B8_DABRR Daboia russelii 2 0.7412
Basic phospholipase A2 VRV-PL-VIIIa P59071 PA2B8_DABRR Daboia russelii 2 0.7412
Liver carboxylesterase 1 P23141 EST1_HUMAN Homo sapiens 2 0.7391
Liver carboxylesterase 1 P23141 EST1_HUMAN Homo sapiens 2 0.7391
Cysteine desulfurase IscS 2 O29689 ISCS2_ARCFU Archaeoglobus fulgidus 3 0.7381
Cysteine desulfurase IscS 2 O29689 ISCS2_ARCFU Archaeoglobus fulgidus 3 0.7381
1-aminocyclopropane-1-carboxylate deaminase Q7M523 1A1D_CYBSA Cyberlindnera saturnus 3 0.7373
1-aminocyclopropane-1-carboxylate deaminase Q7M523 1A1D_CYBSA Cyberlindnera saturnus 3 0.7373
Prostaglandin F2a synthase Q8I6L9 Q8I6L9_TRYCR Trypanosoma cruzi 2 0.7373
Prostaglandin F2a synthase Q8I6L9 Q8I6L9_TRYCR Trypanosoma cruzi 2 0.7373
Nitric oxide synthase oxygenase O34453 NOSO_BACSU Bacillus subtilis 3 0.7367
Nitric oxide synthase oxygenase O34453 NOSO_BACSU Bacillus subtilis 3 0.7367
Glutamate--cysteine ligase P32477 GSH1_YEAST Saccharomyces cerevisiae 3 0.7364
Glutamate--cysteine ligase P32477 GSH1_YEAST Saccharomyces cerevisiae 3 0.7364
Nitric oxide synthase oxygenase O34453 NOSO_BACSU Bacillus subtilis 3 0.7346
Nitric oxide synthase oxygenase O34453 NOSO_BACSU Bacillus subtilis 3 0.7346
Vanillate porin OpdK Q9HUR5 Q9HUR5_PSEAE Pseudomonas aeruginosa 3 0.7345
Vanillate porin OpdK Q9HUR5 Q9HUR5_PSEAE Pseudomonas aeruginosa 3 0.7345
Flavin reductase like domain-containing protein Q4UKE8 Q4UKE8_RICFE Rickettsia felis 3 0.7344
Flavin reductase like domain-containing protein Q4UKE8 Q4UKE8_RICFE Rickettsia felis 3 0.7344
RNA-dependent RNA polymerase Q6A562 Q6A562_9VIRU Thosea asigna virus 2 0.7343
RNA-dependent RNA polymerase Q6A562 Q6A562_9VIRU Thosea asigna virus 2 0.7343
Tetracycline repressor protein class D P0ACT4 TETR4_ECOLX Escherichia coli 3 0.7338
Tetracycline repressor protein class D P0ACT4 TETR4_ECOLX Escherichia coli 3 0.7338
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 O88703 HCN2_MOUSE Mus musculus 3 0.7334
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 O88703 HCN2_MOUSE Mus musculus 3 0.7334
Plasma membrane ATPase Q42932 Q42932_NICPL Nicotiana plumbaginifolia 2 0.7332
Plasma membrane ATPase Q42932 Q42932_NICPL Nicotiana plumbaginifolia 2 0.7332
Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 Q9Y3Z3 SAMH1_HUMAN Homo sapiens 3 0.7331
Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 Q9Y3Z3 SAMH1_HUMAN Homo sapiens 3 0.7331
Fibroblast growth factor receptor 2 P21802 FGFR2_HUMAN Homo sapiens 2 0.7328
Fibroblast growth factor receptor 2 P21802 FGFR2_HUMAN Homo sapiens 2 0.7328
chitinase B0Y2Y2 B0Y2Y2_ASPFC Aspergillus fumigatus 3 0.7318
Capsid protein Q9WBP8 Q9WBP8_9VIRU Adeno-associated virus - 1 2 0.7318
Capsid protein Q9WBP8 Q9WBP8_9VIRU Adeno-associated virus - 1 2 0.7318
chitinase B0Y2Y2 B0Y2Y2_ASPFC Aspergillus fumigatus 3 0.7318
Tannase B3Y018 B3Y018_LACPN Lactiplantibacillus plantarum 3 0.7312
Tannase B3Y018 B3Y018_LACPN Lactiplantibacillus plantarum 3 0.7312
Avidin P02701 AVID_CHICK Gallus gallus 2 0.7309
Mitochondrial poly(A) polymerase F1NBW0 F1NBW0_CHICK Gallus gallus 3 0.7309
Avidin P02701 AVID_CHICK Gallus gallus 2 0.7309
Mitochondrial poly(A) polymerase F1NBW0 F1NBW0_CHICK Gallus gallus 3 0.7309
Cytosolic IMP-GMP specific 5'-nucleotidase Q5ZZB6 Q5ZZB6_LEGPH Legionella pneumophila subsp. pneumophila 3 0.7308
Cytosolic IMP-GMP specific 5'-nucleotidase Q5ZZB6 Q5ZZB6_LEGPH Legionella pneumophila subsp. pneumophila 3 0.7308
Queuine tRNA-ribosyltransferase P28720 TGT_ZYMMO Zymomonas mobilis subsp. mobilis 2 0.7298
Tryptophan synthase alpha chain P00929 TRPA_SALTY Salmonella typhimurium 4 0.7298
Queuine tRNA-ribosyltransferase P28720 TGT_ZYMMO Zymomonas mobilis subsp. mobilis 2 0.7298
Tryptophan synthase alpha chain P00929 TRPA_SALTY Salmonella typhimurium 4 0.7298
Queuine tRNA-ribosyltransferase P28720 TGT_ZYMMO Zymomonas mobilis subsp. mobilis 3 0.7296
Tyrosine 3-monooxygenase P04177 TY3H_RAT Rattus norvegicus 3 0.7296
Queuine tRNA-ribosyltransferase P28720 TGT_ZYMMO Zymomonas mobilis subsp. mobilis 3 0.7296
Tyrosine 3-monooxygenase P04177 TY3H_RAT Rattus norvegicus 3 0.7296
Histone-lysine N-methyltransferase EHMT1 Q9H9B1 EHMT1_HUMAN Homo sapiens 3 0.7275
Histone-lysine N-methyltransferase EHMT1 Q9H9B1 EHMT1_HUMAN Homo sapiens 3 0.7275
L-lactate dehydrogenase A chain P13491 LDHA_RABIT Oryctolagus cuniculus 2 0.7266
L-lactate dehydrogenase A chain P13491 LDHA_RABIT Oryctolagus cuniculus 2 0.7266
Chaperone protein ClpB Q9RA63 CLPB_THET8 Thermus thermophilus 3 0.7264
ADP-ribosylation factor 1 P84077 ARF1_HUMAN Homo sapiens 2 0.7264
ADP-ribosylation factor 1 P84077 ARF1_HUMAN Homo sapiens 2 0.7264
Chaperone protein ClpB Q9RA63 CLPB_THET8 Thermus thermophilus 3 0.7264
Carbonic anhydrase Q39588 Q39588_CHLRE Chlamydomonas reinhardtii 3 0.7263
Carbonic anhydrase Q39588 Q39588_CHLRE Chlamydomonas reinhardtii 3 0.7263
Guanylate kinase P15454 KGUA_YEAST Saccharomyces cerevisiae 3 0.7260
Guanylate kinase P15454 KGUA_YEAST Saccharomyces cerevisiae 3 0.7260
Albumin P02768 ALBU_HUMAN Homo sapiens 3 0.7259
Albumin P02768 ALBU_HUMAN Homo sapiens 3 0.7259
cAMP-dependent protein kinase type I-alpha regulatory subunit P00514 KAP0_BOVIN Bos taurus 2 0.7256
cAMP-dependent protein kinase type I-alpha regulatory subunit P00514 KAP0_BOVIN Bos taurus 2 0.7256
5-methylthioadenosine/S-adenosylhomocysteine deaminase Q7NZ90 Q7NZ90_CHRVO Chromobacterium violaceum 2 0.7252
5-methylthioadenosine/S-adenosylhomocysteine deaminase Q7NZ90 Q7NZ90_CHRVO Chromobacterium violaceum 2 0.7252
Pyridoxal kinase O00764 PDXK_HUMAN Homo sapiens 2 0.7251
Pyridoxal kinase O00764 PDXK_HUMAN Homo sapiens 2 0.7251
5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase P0AF12 MTNN_ECOLI Escherichia coli 2 0.7249
5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase P0AF12 MTNN_ECOLI Escherichia coli 2 0.7249
Toluene-4-monooxygenase system, hydroxylase component subunit alpha Q00456 TMOA_PSEME Pseudomonas mendocina 2 0.7245
Toluene-4-monooxygenase system, hydroxylase component subunit alpha Q00456 TMOA_PSEME Pseudomonas mendocina 2 0.7245
Alpha/beta hydrolase fold A5VAT9 A5VAT9_SPHWW Sphingomonas wittichii 2 0.7243
Alpha/beta hydrolase fold A5VAT9 A5VAT9_SPHWW Sphingomonas wittichii 2 0.7243
APH(2'')-Id O68183 O68183_ENTCA Enterococcus casseliflavus 3 0.7239
APH(2'')-Id O68183 O68183_ENTCA Enterococcus casseliflavus 3 0.7239
Dihydropteroate synthase Q81VW8 Q81VW8_BACAN Bacillus anthracis 3 0.7227
Dihydropteroate synthase Q81VW8 Q81VW8_BACAN Bacillus anthracis 3 0.7227
Succinyl-CoA:acetate CoA-transferase B3EY95 SCACT_ACEAC Acetobacter aceti 2 0.7224
Succinyl-CoA:acetate CoA-transferase B3EY95 SCACT_ACEAC Acetobacter aceti 2 0.7224
Diphtheria toxin P00588 DTX_CORBE Corynephage beta 2 0.7223
Diphtheria toxin P00588 DTX_CORBE Corynephage beta 2 0.7223
Cyclin-dependent kinase 2 P24941 CDK2_HUMAN Homo sapiens 2 0.7222
Cyclin-dependent kinase 2 P24941 CDK2_HUMAN Homo sapiens 2 0.7222
Ribonuclease J H9CZL7 H9CZL7_DEIRD Deinococcus radiodurans 3 0.7222
Ribonuclease J H9CZL7 H9CZL7_DEIRD Deinococcus radiodurans 3 0.7222
Carbonic anhydrase 2 P00918 CAH2_HUMAN Homo sapiens 2 0.7221
Carbonic anhydrase 2 P00918 CAH2_HUMAN Homo sapiens 2 0.7221
Tetracycline repressor protein class D P0ACT4 TETR4_ECOLX Escherichia coli 2 0.7213
Tetracycline repressor protein class D P0ACT4 TETR4_ECOLX Escherichia coli 2 0.7213
Nitric oxide synthase, inducible P29477 NOS2_MOUSE Mus musculus 2 0.7200
Nitric oxide synthase, inducible P29477 NOS2_MOUSE Mus musculus 2 0.7200
Thymidylate synthase P00469 TYSY_LACCA Lacticaseibacillus casei 3 0.7200
Thymidylate synthase P00469 TYSY_LACCA Lacticaseibacillus casei 3 0.7200
NAD-dependent protein deacetylase Q9WYW0 NPD_THEMA Thermotoga maritima 2 0.7197
NAD-dependent protein deacetylase Q9WYW0 NPD_THEMA Thermotoga maritima 2 0.7197
HTH-type transcriptional repressor PurR P0ACP7 PURR_ECOLI Escherichia coli 3 0.7193
HTH-type transcriptional repressor PurR P0ACP7 PURR_ECOLI Escherichia coli 3 0.7193
DNA ligase P43813 DNLJ_HAEIN Haemophilus influenzae 3 0.7191
DNA ligase P43813 DNLJ_HAEIN Haemophilus influenzae 3 0.7191
Fibroblast growth factor receptor 2 P21802 FGFR2_HUMAN Homo sapiens 2 0.7190
Fibroblast growth factor receptor 2 P21802 FGFR2_HUMAN Homo sapiens 2 0.7190
Poly [ADP-ribose] polymerase 1 P09874 PARP1_HUMAN Homo sapiens 2 0.7189
Poly [ADP-ribose] polymerase 1 P09874 PARP1_HUMAN Homo sapiens 2 0.7189
Ceramide transfer protein Q9Y5P4 CERT_HUMAN Homo sapiens 2 0.7184
Anthranilate phosphoribosyltransferase P50384 TRPD_SACS2 Saccharolobus solfataricus 3 0.7184
Ceramide transfer protein Q9Y5P4 CERT_HUMAN Homo sapiens 2 0.7184
Anthranilate phosphoribosyltransferase P50384 TRPD_SACS2 Saccharolobus solfataricus 3 0.7184
CalS13 Q8KND8 Q8KND8_MICEC Micromonospora echinospora 3 0.7175
CalS13 Q8KND8 Q8KND8_MICEC Micromonospora echinospora 3 0.7175
Nucleoside diphosphate kinase Q5UQL3 NDK_MIMIV Acanthamoeba polyphaga mimivirus 2 0.7172
Nucleoside diphosphate kinase Q5UQL3 NDK_MIMIV Acanthamoeba polyphaga mimivirus 2 0.7172
Phospholipase A2, major isoenzyme P00592 PA21B_PIG Sus scrofa 3 0.7162
Phospholipase A2, major isoenzyme P00592 PA21B_PIG Sus scrofa 3 0.7162
Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 Q9Y3Z3 SAMH1_HUMAN Homo sapiens 3 0.7159
Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 Q9Y3Z3 SAMH1_HUMAN Homo sapiens 3 0.7159
Cyclic nucleotide-gated potassium channel mll3241 Q98GN8 CNGK1_RHILO Mesorhizobium japonicum) 3 0.7153
Cyclic nucleotide-gated potassium channel mll3241 Q98GN8 CNGK1_RHILO Mesorhizobium japonicum) 3 0.7153
Methionine aminopeptidase P0AE18 MAP1_ECOLI Escherichia coli 2 0.7148
Methionine aminopeptidase P0AE18 MAP1_ECOLI Escherichia coli 2 0.7148
Cyclic GMP-AMP phosphodiesterase SMPDL3A Q92484 ASM3A_HUMAN Homo sapiens 2 0.7147
Cyclic GMP-AMP phosphodiesterase SMPDL3A Q92484 ASM3A_HUMAN Homo sapiens 2 0.7147
Ephrin type-B receptor 2 P54763 EPHB2_MOUSE Mus musculus 2 0.7146
Ephrin type-B receptor 2 P54763 EPHB2_MOUSE Mus musculus 2 0.7146
HTH-type transcriptional repressor PurR P0ACP7 PURR_ECOLI Escherichia coli 3 0.7145
HTH-type transcriptional repressor PurR P0ACP7 PURR_ECOLI Escherichia coli 3 0.7145
Oxygen-insensitive NAD(P)H nitroreductase P38489 NFSB_ECOLI Escherichia coli 3 0.7140
Oxygen-insensitive NAD(P)H nitroreductase P38489 NFSB_ECOLI Escherichia coli 3 0.7140
Prothrombin P00734 THRB_HUMAN Homo sapiens 3 0.7140
Prothrombin P00734 THRB_HUMAN Homo sapiens 3 0.7140
Copper-transporting ATPase 1 Q04656 ATP7A_HUMAN Homo sapiens 3 0.7129
Copper-transporting ATPase 1 Q04656 ATP7A_HUMAN Homo sapiens 3 0.7129
Tannase B3Y018 B3Y018_LACPN Lactiplantibacillus plantarum 3 0.7128
Tannase B3Y018 B3Y018_LACPN Lactiplantibacillus plantarum 3 0.7128
Glutamate receptor ionotropic, kainate 1 P22756 GRIK1_RAT Rattus norvegicus 2 0.7125
Glutamate receptor ionotropic, kainate 1 P22756 GRIK1_RAT Rattus norvegicus 2 0.7125
Tryptophan synthase alpha chain P00929 TRPA_SALTY Salmonella typhimurium 3 0.7121
Tryptophan synthase alpha chain P00929 TRPA_SALTY Salmonella typhimurium 3 0.7121
Thymidine kinase P0DTH5 KITH_HHV11 Human herpesvirus 1 2 0.7120
Thymidine kinase P0DTH5 KITH_HHV11 Human herpesvirus 1 2 0.7120
Multidrug efflux pump subunit AcrB P31224 ACRB_ECOLI Escherichia coli 3 0.7112
Aspartate aminotransferase P00509 AAT_ECOLI Escherichia coli 3 0.7112
Multidrug efflux pump subunit AcrB P31224 ACRB_ECOLI Escherichia coli 3 0.7112
Aspartate aminotransferase P00509 AAT_ECOLI Escherichia coli 3 0.7112
3'-5' exoribonuclease Rv2179c P9WJ73 EXRBN_MYCTU Mycobacterium tuberculosis 2 0.7111
3'-5' exoribonuclease Rv2179c P9WJ73 EXRBN_MYCTU Mycobacterium tuberculosis 2 0.7111
Endothiapepsin P11838 CARP_CRYPA Cryphonectria parasitica 3 0.7111
Endothiapepsin P11838 CARP_CRYPA Cryphonectria parasitica 3 0.7111
Nitric oxide synthase, inducible P29477 NOS2_MOUSE Mus musculus 2 0.7106
Nitric oxide synthase, inducible P29477 NOS2_MOUSE Mus musculus 2 0.7106
Nitric oxide synthase, inducible P29477 NOS2_MOUSE Mus musculus 3 0.7103
Nitric oxide synthase, inducible P29477 NOS2_MOUSE Mus musculus 3 0.7103
Nitric oxide synthase, inducible P29477 NOS2_MOUSE Mus musculus 3 0.7090
Nitric oxide synthase, inducible P29477 NOS2_MOUSE Mus musculus 3 0.7090
2-methyl-3-hydroxypyridine-5-carboxylic acid oxygenase Q988D3 Q988D3_RHILO Mesorhizobium japonicum) 3 0.7089
2-methyl-3-hydroxypyridine-5-carboxylic acid oxygenase Q988D3 Q988D3_RHILO Mesorhizobium japonicum) 3 0.7089
Nitric oxide synthase, inducible P29477 NOS2_MOUSE Mus musculus 2 0.7088
L-lactate dehydrogenase A chain P04642 LDHA_RAT Rattus norvegicus 3 0.7088
L-lactate dehydrogenase A chain P04642 LDHA_RAT Rattus norvegicus 3 0.7088
Nitric oxide synthase, inducible P29477 NOS2_MOUSE Mus musculus 2 0.7088
Bifunctional epoxide hydrolase 2 P34913 HYES_HUMAN Homo sapiens 2 0.7087
Bifunctional epoxide hydrolase 2 P34913 HYES_HUMAN Homo sapiens 2 0.7087
Casein kinase II subunit alpha P68400 CSK21_HUMAN Homo sapiens 2 0.7085
Casein kinase II subunit alpha P68400 CSK21_HUMAN Homo sapiens 2 0.7085
Mitochondrial poly(A) polymerase F1NBW0 F1NBW0_CHICK Gallus gallus 2 0.7077
Mitochondrial poly(A) polymerase F1NBW0 F1NBW0_CHICK Gallus gallus 2 0.7077
2',3'-cyclic-nucleotide 3'-phosphodiesterase P16330 CN37_MOUSE Mus musculus 3 0.7075
2',3'-cyclic-nucleotide 3'-phosphodiesterase P16330 CN37_MOUSE Mus musculus 3 0.7075
ATP-dependent molecular chaperone HSP82 P02829 HSP82_YEAST Saccharomyces cerevisiae 2 0.7073
ATP-dependent molecular chaperone HSP82 P02829 HSP82_YEAST Saccharomyces cerevisiae 2 0.7073
Holliday junction branch migration complex subunit RuvB Q9PMT7 RUVB_CAMJE Campylobacter jejuni subsp. jejuni serotype O:2 2 0.7072
Holliday junction branch migration complex subunit RuvB Q9PMT7 RUVB_CAMJE Campylobacter jejuni subsp. jejuni serotype O:2 2 0.7072
Carbonic anhydrase 5A, mitochondrial P23589 CAH5A_MOUSE Mus musculus 3 0.7071
Carbonic anhydrase 5A, mitochondrial P23589 CAH5A_MOUSE Mus musculus 3 0.7071
2',3'-cyclic-nucleotide 3'-phosphodiesterase P16330 CN37_MOUSE Mus musculus 2 0.7069
2',3'-cyclic-nucleotide 3'-phosphodiesterase P16330 CN37_MOUSE Mus musculus 2 0.7069
2',3'-cyclic-nucleotide 3'-phosphodiesterase P16330 CN37_MOUSE Mus musculus 2 0.7064
2',3'-cyclic-nucleotide 3'-phosphodiesterase P16330 CN37_MOUSE Mus musculus 2 0.7064
Streptavidin P22629 SAV_STRAV Streptomyces avidinii 2 0.7063
Streptavidin P22629 SAV_STRAV Streptomyces avidinii 2 0.7063
N-acetyltransferase domain-containing protein Q9HV14 Q9HV14_PSEAE Pseudomonas aeruginosa 3 0.7061
N-acetyltransferase domain-containing protein Q9HV14 Q9HV14_PSEAE Pseudomonas aeruginosa 3 0.7061
3',5'-cyclic-AMP phosphodiesterase 4B Q07343 PDE4B_HUMAN Homo sapiens 3 0.7060
3',5'-cyclic-AMP phosphodiesterase 4B Q07343 PDE4B_HUMAN Homo sapiens 3 0.7060
Catalase-peroxidase Q3JNW6 KATG_BURP1 Burkholderia pseudomallei 2 0.7059
Polymerase acidic protein C3W5S0 C3W5S0_I09A0 Influenza A virus 2 0.7059
Polymerase acidic protein C3W5S0 C3W5S0_I09A0 Influenza A virus 2 0.7059
Catalase-peroxidase Q3JNW6 KATG_BURP1 Burkholderia pseudomallei 2 0.7059
Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 2 O95340 PAPS2_HUMAN Homo sapiens 2 0.7057
Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 2 O95340 PAPS2_HUMAN Homo sapiens 2 0.7057
Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase Q05603 COBT_SALTY Salmonella typhimurium 2 0.7054
Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase Q05603 COBT_SALTY Salmonella typhimurium 2 0.7054
Mitochondrial dynamics protein MIEF1 Q9NQG6 MID51_HUMAN Homo sapiens 3 0.7053
Mitochondrial dynamics protein MIEF1 Q9NQG6 MID51_HUMAN Homo sapiens 3 0.7053
Nitric oxide synthase, inducible P29477 NOS2_MOUSE Mus musculus 2 0.7051
Nitric oxide synthase, inducible P29477 NOS2_MOUSE Mus musculus 2 0.7051
Purine nucleoside phosphorylase DeoD-type P0ABP9 DEOD_ECO57 Escherichia coli O157:H7 2 0.7043
Purine nucleoside phosphorylase DeoD-type P0ABP9 DEOD_ECO57 Escherichia coli O157:H7 2 0.7043
Virulence sensor histidine kinase PhoQ P0DM80 PHOQ_SALTY Salmonella typhimurium 3 0.7038
rRNA N-glycosylase D9J2T9 D9J2T9_MOMBA Momordica balsamina 3 0.7038
rRNA N-glycosylase D9J2T9 D9J2T9_MOMBA Momordica balsamina 3 0.7038
Virulence sensor histidine kinase PhoQ P0DM80 PHOQ_SALTY Salmonella typhimurium 3 0.7038
Queuine tRNA-ribosyltransferase P28720 TGT_ZYMMO Zymomonas mobilis subsp. mobilis 3 0.7033
Queuine tRNA-ribosyltransferase P28720 TGT_ZYMMO Zymomonas mobilis subsp. mobilis 3 0.7033
Beta-1,4-galactosyltransferase 1 P08037 B4GT1_BOVIN Bos taurus 3 0.7030
Beta-1,4-galactosyltransferase 1 P08037 B4GT1_BOVIN Bos taurus 3 0.7030
Endothiapepsin P11838 CARP_CRYPA Cryphonectria parasitica 3 0.7018
Endothiapepsin P11838 CARP_CRYPA Cryphonectria parasitica 3 0.7018
4-diphosphocytidyl-2-C-methyl-D-erythritol kinase O67060 ISPE_AQUAE Aquifex aeolicus 2 0.7014
4-diphosphocytidyl-2-C-methyl-D-erythritol kinase O67060 ISPE_AQUAE Aquifex aeolicus 2 0.7014
Ribosome-inactivating protein 3 P25891 RIP3_MAIZE Zea mays 2 0.7011
Ribosome-inactivating protein 3 P25891 RIP3_MAIZE Zea mays 2 0.7011
Proline iminopeptidase O32449 PIP_SERMA Serratia marcescens 2 0.7011
Proline iminopeptidase O32449 PIP_SERMA Serratia marcescens 2 0.7011
D-alanine aminotransferase P19938 DAAA_BACYM Bacillus sp 3 0.7009
Mitogen-activated protein kinase 8 P45983 MK08_HUMAN Homo sapiens 2 0.7009
D-alanine aminotransferase P19938 DAAA_BACYM Bacillus sp 3 0.7009
Mitogen-activated protein kinase 8 P45983 MK08_HUMAN Homo sapiens 2 0.7009
SKP1-like protein 1A Q39255 SKP1A_ARATH Arabidopsis thaliana 3 0.7006
SKP1-like protein 1A Q39255 SKP1A_ARATH Arabidopsis thaliana 3 0.7006
Malate synthase G P9WK17 MASZ_MYCTU Mycobacterium tuberculosis 3 0.7006
Malate synthase G P9WK17 MASZ_MYCTU Mycobacterium tuberculosis 3 0.7006

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