6-cis-amentadione-1'-methyl ether - Compound Card

6-cis-amentadione-1'-methyl ether

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6-cis-amentadione-1'-methyl ether

Structure
Zoomed Structure
  • Family: Sargassaceae-Fucaceae
  • Kingdom: Chromista
  • Class: Terpenoid
    • Subclass: Meroditerpenoid
Canonical Smiles COc1c(C/C=C(/CC(=O)/C=C(\CCCC(C(=O)/C=C/C(O)(C)C)C)/C)\C)cc(cc1C)O
InChI InChI=1S/C28H40O5/c1-19(9-8-10-21(3)26(31)13-14-28(5,6)32)15-24(29)16-20(2)11-12-23-18-25(30)17-22(4)27(23)33-7/h11,13-15,17-18,21,30,32H,8-10,12,16H2,1-7H3/b14-13+,19-15-,20-11+
InChIKey SOAOSAITFDKYRN-IUFXIEQHSA-N
Formula C28H40O5
HBA 5
HBD 2
MW 456.62
Rotatable Bonds 13
TPSA 83.83
LogP 5.81
Number Rings 1
Number Aromatic Rings 1
Heavy Atom Count 33
Formal Charge 0
Fraction CSP3 0.5
Exact Mass 456.29
Number of Lipinski Rule Violations 1
# Species Family Kingdom NCBI Taxonomy ID
1 Cystoseira usneoides Sargassaceae-Fucaceae Chromista 590723

Showing of synonyms

  • de Los Reyes C, Zbakh H, et al. (2013). Antioxidant and anti-inflammatory meroterpenoids from the brown alga Cystoseira usneoides. Journal of Natural Products,2013,76(4),621-629. [View] [PubMed]
Pubchem: 14412731
Nmrshiftdb2: 70030209

No compound-protein relationship available.

Structure

SMILES: c1ccccc1

Level: 0

Mol. Weight: 78.11 g/mol

Antiinflammatory property
Antioxidant

Absorption

Caco-2 (logPapp)
-4.74
Human Oral Bioavailability 20%
Bioavailable
Human Intestinal Absorption
Absorbed
Madin-Darby Canine Kidney
-4.710
Human Oral Bioavailability 50%
Bioavailable
P-Glycoprotein Inhibitor
Non-Inhibitor
P-Glycoprotein Substrate
Non-Substrate
Skin Permeability
-2.74

Distribution

Blood-Brain Barrier (CNS)
-
Blood-Brain Barrier
Non-Penetrable
Fraction Unbound (Human)
0.950
Plasma Protein Binding
63.31
Steady State Volume of Distribution
-

Metabolism

Breast Cancer Resistance Protein
Non-Inhibitor
CYP 1A2 Inhibitor
Inhibitor
CYP 1A2 Substrate
Substrate
CYP 2C19 Inhibitor
Non-Inhibitor
CYP 2C19 Substrate
Substrate
CYP 2C9 Inhibitor
Inhibitor
CYP 2C9 Substrate
Non-Substrate
CYP 2D6 Inhibitor
Non-Inhibitor
CYP 2D6 Substrate
Non-Substrate
CYP 3A4 Inhibitor
Inhibitor
CYP 3A4 Substrate
Substrate
OATP1B1
Inhibitor
OATP1B3
Non-Inhibitor

Excretion

Clearance
4.270
Organic Cation Transporter 2
Non-Inhibitor
Half-Life of Drug
-

Toxicity

AMES Mutagenesis
Safe
Avian
Safe
Bee
Toxic
Bioconcentration Factor
0.850
Biodegradation
Safe
Carcinogenesis
Toxic
Crustacean
Toxic
Liver Injury I (DILI)
Safe
Eye Corrosion
Safe
Eye Irritation
Safe
Maximum Tolerated Dose
0.390
Liver Injury II
Toxic
hERG Blockers
Safe
Daphnia Maga
6.990
Micronucleos
Safe
NR-AhR
Safe
NR-AR
Safe
NR-AR-LBD
Safe
NR-Aromatase
Safe
NR-ER
Safe
NR-ER-LBD
Safe
NR-GR
Safe
NR-PPAR-gamma
Safe
NR-TR
Safe
T. Pyriformis
-29.310
Rat (Acute)
2.220
Rat (Chronic Oral)
2.320
Fathead Minnow
5.540
Respiratory Disease
Toxic
Skin Sensitisation
Toxic
SR-ARE
Toxic
SR-ATAD5
Safe
SR-HSE
Safe
SR-MMP
Toxic
SR-p53
Safe

General Properties

Boiling Point
469.930
Hydration Free Energy
-3.830
Log(D) at pH=7.4
3.850
Log(P)
4.77
Log S
-5.83
Log(Vapor Pressure)
-7.85
Melting Point
100.04
pKa Acid
11.23
pKa Basic
5.21
Protein Name UniProt ID Entry Name Species #Pharmacophore Points Probability (0.7 ≤ Tversky Score ≤ 1.0)
Corticosteroid-binding globulin P08185 CBG_HUMAN Homo sapiens 3 0.9473
Corticosteroid-binding globulin P08185 CBG_HUMAN Homo sapiens 3 0.9473
Retinoic acid receptor RXR-alpha P19793 RXRA_HUMAN Homo sapiens 3 0.9402
Retinoic acid receptor RXR-alpha P19793 RXRA_HUMAN Homo sapiens 3 0.9402
Type IV / VI secretion system DotU domain-containing protein Q9KN50 Q9KN50_VIBCH Vibrio cholerae serotype O1 3 0.9394
Type IV / VI secretion system DotU domain-containing protein Q9KN50 Q9KN50_VIBCH Vibrio cholerae serotype O1 3 0.9394
Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase F6MZ55 F6MZ55_9FIRM Sporomusa ovata 3 0.9381
Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase F6MZ55 F6MZ55_9FIRM Sporomusa ovata 3 0.9381
Steroid Delta-isomerase P07445 SDIS_PSEPU Pseudomonas putida 3 0.9323
Steroid Delta-isomerase P07445 SDIS_PSEPU Pseudomonas putida 3 0.9323
Carbonic anhydrase 12 O43570 CAH12_HUMAN Homo sapiens 3 0.9134
Carbonic anhydrase 12 O43570 CAH12_HUMAN Homo sapiens 3 0.9134
Na(+):neurotransmitter symporter (Snf family) O67854 O67854_AQUAE Aquifex aeolicus 3 0.9126
Na(+):neurotransmitter symporter (Snf family) O67854 O67854_AQUAE Aquifex aeolicus 3 0.9126
High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A O76083 PDE9A_HUMAN Homo sapiens 3 0.9101
High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A O76083 PDE9A_HUMAN Homo sapiens 3 0.9101
Heat shock protein HSP 90-alpha P07900 HS90A_HUMAN Homo sapiens 3 0.9025
Heat shock protein HSP 90-alpha P07900 HS90A_HUMAN Homo sapiens 3 0.9025
High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A O76083 PDE9A_HUMAN Homo sapiens 3 0.8939
High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A O76083 PDE9A_HUMAN Homo sapiens 3 0.8939
3',5'-cyclic-AMP phosphodiesterase 4D Q08499 PDE4D_HUMAN Homo sapiens 3 0.8920
3',5'-cyclic-AMP phosphodiesterase 4D Q08499 PDE4D_HUMAN Homo sapiens 3 0.8920
11-beta-hydroxysteroid dehydrogenase 1 P50172 DHI1_MOUSE Mus musculus 3 0.8917
11-beta-hydroxysteroid dehydrogenase 1 P50172 DHI1_MOUSE Mus musculus 3 0.8917
Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase Q9TQS6 DHDH_MACFA Macaca fascicularis 3 0.8899
Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase Q9TQS6 DHDH_MACFA Macaca fascicularis 3 0.8899
cGMP-dependent 3',5'-cyclic phosphodiesterase O00408 PDE2A_HUMAN Homo sapiens 3 0.8855
cGMP-dependent 3',5'-cyclic phosphodiesterase O00408 PDE2A_HUMAN Homo sapiens 3 0.8855
Thiamine-phosphate synthase P39594 THIE_BACSU Bacillus subtilis 3 0.8823
Thiamine-phosphate synthase P39594 THIE_BACSU Bacillus subtilis 3 0.8823
Acetylcholinesterase P21836 ACES_MOUSE Mus musculus 3 0.8822
Acetylcholinesterase P21836 ACES_MOUSE Mus musculus 3 0.8822
Uncharacterized protein YML079W Q03629 YMH9_YEAST Saccharomyces cerevisiae 3 0.8803
Uncharacterized protein YML079W Q03629 YMH9_YEAST Saccharomyces cerevisiae 3 0.8803
CmeR Q7B8P6 Q7B8P6_CAMJU Campylobacter jejuni 3 0.8772
CmeR Q7B8P6 Q7B8P6_CAMJU Campylobacter jejuni 3 0.8772
RNA polymerase sigma factor SigA Q5SKW1 Q5SKW1_THET8 Thermus thermophilus 3 0.8727
RNA polymerase sigma factor SigA Q5SKW1 Q5SKW1_THET8 Thermus thermophilus 3 0.8727
Phytohormone-binding protein CSBP A0A1S3THR8 PHBP_VIGRR Vigna radiata var. radiata 3 0.8711
Phytohormone-binding protein CSBP A0A1S3THR8 PHBP_VIGRR Vigna radiata var. radiata 3 0.8711
Succinate dehydrogenase flavoprotein subunit P0AC41 SDHA_ECOLI Escherichia coli 3 0.8692
Succinate dehydrogenase flavoprotein subunit P0AC41 SDHA_ECOLI Escherichia coli 3 0.8692
Soluble acetylcholine receptor Q8WSF8 Q8WSF8_APLCA Aplysia californica 3 0.8642
Soluble acetylcholine receptor Q8WSF8 Q8WSF8_APLCA Aplysia californica 3 0.8642
Albumin P02768 ALBU_HUMAN Homo sapiens 3 0.8589
Albumin P02768 ALBU_HUMAN Homo sapiens 3 0.8589
Methylketone synthase I E0YCS2 E0YCS2_SOLHA Solanum habrochaites 3 0.8513
Methylketone synthase I E0YCS2 E0YCS2_SOLHA Solanum habrochaites 3 0.8513
Cyclin-dependent kinase 2 P24941 CDK2_HUMAN Homo sapiens 3 0.8504
Cyclin-dependent kinase 2 P24941 CDK2_HUMAN Homo sapiens 3 0.8504
Pentaerythritol tetranitrate reductase P71278 P71278_ENTCL Enterobacter cloacae 3 0.8499
Pentaerythritol tetranitrate reductase P71278 P71278_ENTCL Enterobacter cloacae 3 0.8499
Aldo-keto reductase family 1 member C3 P42330 AK1C3_HUMAN Homo sapiens 3 0.8471
Aldo-keto reductase family 1 member C3 P42330 AK1C3_HUMAN Homo sapiens 3 0.8471
ATP-dependent molecular chaperone HSP82 P02829 HSP82_YEAST Saccharomyces cerevisiae 3 0.8456
ATP-dependent molecular chaperone HSP82 P02829 HSP82_YEAST Saccharomyces cerevisiae 3 0.8456
Achbp I6L8L2 I6L8L2_CAPTE Capitella teleta 3 0.8433
Achbp I6L8L2 I6L8L2_CAPTE Capitella teleta 3 0.8433
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A Q9Y233 PDE10_HUMAN Homo sapiens 3 0.8429
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A Q9Y233 PDE10_HUMAN Homo sapiens 3 0.8429
High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A O76083 PDE9A_HUMAN Homo sapiens 3 0.8407
High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A O76083 PDE9A_HUMAN Homo sapiens 3 0.8407
Aldo-keto reductase family 1 member D1 P51857 AK1D1_HUMAN Homo sapiens 3 0.8394
Aldo-keto reductase family 1 member D1 P51857 AK1D1_HUMAN Homo sapiens 3 0.8394
Soluble acetylcholine receptor Q8WSF8 Q8WSF8_APLCA Aplysia californica 3 0.8385
Soluble acetylcholine receptor Q8WSF8 Q8WSF8_APLCA Aplysia californica 3 0.8385
Probable NDP-rhamnosyltransferase Q9ALM8 Q9ALM8_SACSN Saccharopolyspora spinosa 3 0.8373
Probable NDP-rhamnosyltransferase Q9ALM8 Q9ALM8_SACSN Saccharopolyspora spinosa 3 0.8373
D-aminoacyl-tRNA deacylase Q8IIS0 DTD_PLAF7 Plasmodium falciparum 3 0.8367
D-aminoacyl-tRNA deacylase Q8IIS0 DTD_PLAF7 Plasmodium falciparum 3 0.8367
Pteridine reductase, putative Q581W1 Q581W1_TRYB2 Trypanosoma brucei brucei 3 0.8365
Pteridine reductase, putative Q581W1 Q581W1_TRYB2 Trypanosoma brucei brucei 3 0.8365
Casein kinase II subunit alpha P28523 CSK2A_MAIZE Zea mays 3 0.8364
Casein kinase II subunit alpha P28523 CSK2A_MAIZE Zea mays 3 0.8364
Neocarzinostatin P0A3R9 NCZS_STRCZ Streptomyces carzinostaticus 3 0.8325
Neocarzinostatin P0A3R9 NCZS_STRCZ Streptomyces carzinostaticus 3 0.8325
3',5'-cyclic-AMP phosphodiesterase 4D Q08499 PDE4D_HUMAN Homo sapiens 3 0.8312
3',5'-cyclic-AMP phosphodiesterase 4D Q08499 PDE4D_HUMAN Homo sapiens 3 0.8312
Carbonic anhydrase 2 P00918 CAH2_HUMAN Homo sapiens 2 0.8286
Carbonic anhydrase 2 P00918 CAH2_HUMAN Homo sapiens 2 0.8286
Peptidyl-prolyl cis-trans isomerase FKBP1A P62942 FKB1A_HUMAN Homo sapiens 3 0.8280
Peptidyl-prolyl cis-trans isomerase FKBP1A P62942 FKB1A_HUMAN Homo sapiens 3 0.8280
Chitinase Q54276 Q54276_SERMA Serratia marcescens 3 0.8259
Chitinase Q54276 Q54276_SERMA Serratia marcescens 3 0.8259
Ribosyldihydronicotinamide dehydrogenase [quinone] P16083 NQO2_HUMAN Homo sapiens 3 0.8240
Ribosyldihydronicotinamide dehydrogenase [quinone] P16083 NQO2_HUMAN Homo sapiens 3 0.8240
Polyprotein Q80J95 Q80J95_9CALI Murine norovirus 1 3 0.8235
Polyprotein Q80J95 Q80J95_9CALI Murine norovirus 1 3 0.8235
Carbonic anhydrase 2 P00918 CAH2_HUMAN Homo sapiens 3 0.8207
Carbonic anhydrase 2 P00918 CAH2_HUMAN Homo sapiens 3 0.8207
Aldo-keto reductase family 1 member C2 P52895 AK1C2_HUMAN Homo sapiens 3 0.8200
Aldo-keto reductase family 1 member C2 P52895 AK1C2_HUMAN Homo sapiens 3 0.8200
Sex hormone-binding globulin P04278 SHBG_HUMAN Homo sapiens 3 0.8200
Sex hormone-binding globulin P04278 SHBG_HUMAN Homo sapiens 3 0.8200
ADP-ribosylation factor 1 P84077 ARF1_HUMAN Homo sapiens 2 0.8187
ADP-ribosylation factor 1 P84077 ARF1_HUMAN Homo sapiens 2 0.8187
Beta-lactoglobulin P02754 LACB_BOVIN Bos taurus 3 0.8184
Beta-lactoglobulin P02754 LACB_BOVIN Bos taurus 3 0.8184
Aldo-keto reductase family 1 member C2 P52895 AK1C2_HUMAN Homo sapiens 3 0.8135
Aldo-keto reductase family 1 member C2 P52895 AK1C2_HUMAN Homo sapiens 3 0.8135
Aldo-keto reductase family 1 member D1 P51857 AK1D1_HUMAN Homo sapiens 3 0.8110
Aldo-keto reductase family 1 member D1 P51857 AK1D1_HUMAN Homo sapiens 3 0.8110
Photosynthetic reaction center cytochrome c subunit P07173 CYCR_BLAVI Blastochloris viridis 3 0.8084
Photosynthetic reaction center cytochrome c subunit P07173 CYCR_BLAVI Blastochloris viridis 3 0.8084
Sulfotransferase 2B1 O00204 ST2B1_HUMAN Homo sapiens 2 0.8034
Sulfotransferase 2B1 O00204 ST2B1_HUMAN Homo sapiens 2 0.8034
Lactoylglutathione lyase Q9CPU0 LGUL_MOUSE Mus musculus 2 0.8020
Lactoylglutathione lyase Q9CPU0 LGUL_MOUSE Mus musculus 2 0.8020
TDP-4-oxo-6-deoxy-alpha-D-glucose-3,4-oxoisomerase Q6T1W8 FDTA_ANETH Aneurinibacillus thermoaerophilus 3 0.7993
TDP-4-oxo-6-deoxy-alpha-D-glucose-3,4-oxoisomerase Q6T1W8 FDTA_ANETH Aneurinibacillus thermoaerophilus 3 0.7993
Retinol dehydratase Q26490 Q26490_SPOFR Spodoptera frugiperda 3 0.7989
Retinol dehydratase Q26490 Q26490_SPOFR Spodoptera frugiperda 3 0.7989
Casein kinase II subunit alpha P28523 CSK2A_MAIZE Zea mays 3 0.7980
Casein kinase II subunit alpha P28523 CSK2A_MAIZE Zea mays 3 0.7980
Liver carboxylesterase 1 P23141 EST1_HUMAN Homo sapiens 3 0.7966
Liver carboxylesterase 1 P23141 EST1_HUMAN Homo sapiens 3 0.7966
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 P04191 AT2A1_RABIT Oryctolagus cuniculus 3 0.7959
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 P04191 AT2A1_RABIT Oryctolagus cuniculus 3 0.7959
Aldo-keto reductase family 1 member D1 P51857 AK1D1_HUMAN Homo sapiens 2 0.7917
Aldo-keto reductase family 1 member D1 P51857 AK1D1_HUMAN Homo sapiens 2 0.7917
histidine kinase O32393 O32393_ARTPT Arthrospira platensis 3 0.7909
histidine kinase O32393 O32393_ARTPT Arthrospira platensis 3 0.7909
Probable esterase KAI2 Q9SZU7 KAI2_ARATH Arabidopsis thaliana 3 0.7879
Probable esterase KAI2 Q9SZU7 KAI2_ARATH Arabidopsis thaliana 3 0.7879
Aldo-keto reductase family 1 member D1 P51857 AK1D1_HUMAN Homo sapiens 3 0.7868
Aldo-keto reductase family 1 member D1 P51857 AK1D1_HUMAN Homo sapiens 3 0.7868
ActVA 6 protein Q53908 Q53908_STRCH Streptomyces coelicolor 3 0.7865
ActVA 6 protein Q53908 Q53908_STRCH Streptomyces coelicolor 3 0.7865
Acetylcholinesterase P04058 ACES_TETCF Tetronarce californica 3 0.7801
Acetylcholinesterase P04058 ACES_TETCF Tetronarce californica 3 0.7801
Beta-lactoglobulin P02754 LACB_BOVIN Bos taurus 3 0.7794
Beta-lactoglobulin P02754 LACB_BOVIN Bos taurus 3 0.7794
Aldo-keto reductase family 1 member B1 P15121 ALDR_HUMAN Homo sapiens 3 0.7785
Aldo-keto reductase family 1 member B1 P15121 ALDR_HUMAN Homo sapiens 3 0.7785
Cytochrome P450 monooxygenase Q5YNS8 Q5YNS8_NOCFA Nocardia farcinica 3 0.7784
Cytochrome P450 monooxygenase Q5YNS8 Q5YNS8_NOCFA Nocardia farcinica 3 0.7784
3',5'-cyclic-AMP phosphodiesterase 4D Q08499 PDE4D_HUMAN Homo sapiens 3 0.7776
3',5'-cyclic-AMP phosphodiesterase 4D Q08499 PDE4D_HUMAN Homo sapiens 3 0.7776
Acetylcholine-binding protein P58154 ACHP_LYMST Lymnaea stagnalis 3 0.7769
Acetylcholine-binding protein P58154 ACHP_LYMST Lymnaea stagnalis 3 0.7769
Aldo-keto reductase family 1 member B1 P15121 ALDR_HUMAN Homo sapiens 3 0.7762
Aldo-keto reductase family 1 member B1 P15121 ALDR_HUMAN Homo sapiens 3 0.7762
Retinaldehyde-binding protein 1 P12271 RLBP1_HUMAN Homo sapiens 4 0.7751
Retinaldehyde-binding protein 1 P12271 RLBP1_HUMAN Homo sapiens 4 0.7751
Serine/threonine-protein kinase Chk1 O14757 CHK1_HUMAN Homo sapiens 3 0.7738
Serine/threonine-protein kinase Chk1 O14757 CHK1_HUMAN Homo sapiens 3 0.7738
Nuclear receptor subfamily 4immunitygroup A member 1 P22736 NR4A1_HUMAN Homo sapiens 3 0.7727
Nuclear receptor subfamily 4immunitygroup A member 1 P22736 NR4A1_HUMAN Homo sapiens 3 0.7727
Mycinamicin III 3''-O-methyltransferase Q49492 MYCF_MICGR Micromonospora griseorubida 2 0.7725
Aldo-keto reductase family 1 member D1 P51857 AK1D1_HUMAN Homo sapiens 2 0.7725
Mycinamicin III 3''-O-methyltransferase Q49492 MYCF_MICGR Micromonospora griseorubida 2 0.7725
Aldo-keto reductase family 1 member D1 P51857 AK1D1_HUMAN Homo sapiens 2 0.7725
Sulfide-quinone reductase B7JBP8 SQRD_ACIF2 Acidithiobacillus ferrooxidans) 3 0.7710
Sulfide-quinone reductase B7JBP8 SQRD_ACIF2 Acidithiobacillus ferrooxidans) 3 0.7710
Acetylcholinesterase P04058 ACES_TETCF Tetronarce californica 3 0.7693
Acetylcholinesterase P04058 ACES_TETCF Tetronarce californica 3 0.7693
17-beta-hydroxysteroid dehydrogenase 14 Q9BPX1 DHB14_HUMAN Homo sapiens 3 0.7674
17-beta-hydroxysteroid dehydrogenase 14 Q9BPX1 DHB14_HUMAN Homo sapiens 3 0.7674
Acetylcholinesterase P04058 ACES_TETCF Tetronarce californica 3 0.7670
Acetylcholinesterase P04058 ACES_TETCF Tetronarce californica 3 0.7670
Purine nucleoside phosphorylase P00491 PNPH_HUMAN Homo sapiens 3 0.7667
Purine nucleoside phosphorylase P00491 PNPH_HUMAN Homo sapiens 3 0.7667
Carbonic anhydrase 2 P00918 CAH2_HUMAN Homo sapiens 2 0.7666
Carbonic anhydrase 2 P00918 CAH2_HUMAN Homo sapiens 2 0.7666
Peptidyl-prolyl cis-trans isomerase FKBP1A P62942 FKB1A_HUMAN Homo sapiens 4 0.7656
Peptidyl-prolyl cis-trans isomerase FKBP1A P62942 FKB1A_HUMAN Homo sapiens 4 0.7656
Retinoic acid receptor RXR-alpha P19793 RXRA_HUMAN Homo sapiens 3 0.7654
Retinoic acid receptor RXR-alpha P19793 RXRA_HUMAN Homo sapiens 3 0.7654
Ribosyldihydronicotinamide dehydrogenase [quinone] P16083 NQO2_HUMAN Homo sapiens 3 0.7647
Ribosyldihydronicotinamide dehydrogenase [quinone] P16083 NQO2_HUMAN Homo sapiens 3 0.7647
Acetylcholinesterase P04058 ACES_TETCF Tetronarce californica 3 0.7646
Acetylcholinesterase P04058 ACES_TETCF Tetronarce californica 3 0.7646
Steroid Delta-isomerase P07445 SDIS_PSEPU Pseudomonas putida 2 0.7640
Steroid Delta-isomerase P07445 SDIS_PSEPU Pseudomonas putida 2 0.7640
Genome polyprotein P26663 POLG_HCVBK Hepatitis C virus genotype 1b 3 0.7637
Beta-secretase 1 P56817 BACE1_HUMAN Homo sapiens 2 0.7637
Beta-secretase 1 P56817 BACE1_HUMAN Homo sapiens 2 0.7637
Genome polyprotein P26663 POLG_HCVBK Hepatitis C virus genotype 1b 3 0.7637
Aldo-keto reductase family 1 member C2 P52895 AK1C2_HUMAN Homo sapiens 2 0.7636
Aldo-keto reductase family 1 member C2 P52895 AK1C2_HUMAN Homo sapiens 2 0.7636
Peptidyl-prolyl cis-trans isomerase FKBP1A P62942 FKB1A_HUMAN Homo sapiens 3 0.7633
Peptidyl-prolyl cis-trans isomerase FKBP1A P62942 FKB1A_HUMAN Homo sapiens 3 0.7633
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 P04191 AT2A1_RABIT Oryctolagus cuniculus 3 0.7629
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 P04191 AT2A1_RABIT Oryctolagus cuniculus 3 0.7629
Heat shock protein HSP 90-alpha P07900 HS90A_HUMAN Homo sapiens 3 0.7609
Heat shock protein HSP 90-alpha P07900 HS90A_HUMAN Homo sapiens 3 0.7609
Nitric oxide synthase 1 P29476 NOS1_RAT Rattus norvegicus 3 0.7605
Nitric oxide synthase 1 P29476 NOS1_RAT Rattus norvegicus 3 0.7605
Albumin P02769 ALBU_BOVIN Bos taurus 3 0.7601
Albumin P02769 ALBU_BOVIN Bos taurus 3 0.7601
Pentaerythritol tetranitrate reductase P71278 P71278_ENTCL Enterobacter cloacae 2 0.7599
Pentaerythritol tetranitrate reductase P71278 P71278_ENTCL Enterobacter cloacae 2 0.7599
Enoyl-[acyl-carrier-protein] reductase [NADH] P9WGR0 INHA_MYCTO Mycobacterium tuberculosis 4 0.7587
Enoyl-[acyl-carrier-protein] reductase [NADH] P9WGR0 INHA_MYCTO Mycobacterium tuberculosis 4 0.7587
Retinol-binding protein 2 P50120 RET2_HUMAN Homo sapiens 3 0.7577
Retinol-binding protein 2 P50120 RET2_HUMAN Homo sapiens 3 0.7577
Beta-secretase 1 P56817 BACE1_HUMAN Homo sapiens 2 0.7573
Beta-secretase 1 P56817 BACE1_HUMAN Homo sapiens 2 0.7573
Aldo-keto reductase family 1 member C2 P52895 AK1C2_HUMAN Homo sapiens 2 0.7568
Aldo-keto reductase family 1 member C2 P52895 AK1C2_HUMAN Homo sapiens 2 0.7568
cGMP-specific 3',5'-cyclic phosphodiesterase O76074 PDE5A_HUMAN Homo sapiens 3 0.7562
cGMP-specific 3',5'-cyclic phosphodiesterase O76074 PDE5A_HUMAN Homo sapiens 3 0.7562
Rhodopsin P02699 OPSD_BOVIN Bos taurus 3 0.7547
Rhodopsin P02699 OPSD_BOVIN Bos taurus 3 0.7547
Thiamine-phosphate synthase P39594 THIE_BACSU Bacillus subtilis 3 0.7545
Thiamine-phosphate synthase P39594 THIE_BACSU Bacillus subtilis 3 0.7545
11-beta-hydroxysteroid dehydrogenase 1 P28845 DHI1_HUMAN Homo sapiens 3 0.7539
11-beta-hydroxysteroid dehydrogenase 1 P28845 DHI1_HUMAN Homo sapiens 3 0.7539
3-alpha-hydroxysteroid dehydrogenase P23457 DIDH_RAT Rattus norvegicus 3 0.7529
3-alpha-hydroxysteroid dehydrogenase P23457 DIDH_RAT Rattus norvegicus 3 0.7529
3-ketosteroid dehydrogenase Q9RA02 Q9RA02_RHOER Rhodococcus erythropolis 3 0.7526
3-ketosteroid dehydrogenase Q9RA02 Q9RA02_RHOER Rhodococcus erythropolis 3 0.7526
Retinol-binding protein 1 P02696 RET1_RAT Rattus norvegicus 3 0.7522
Retinol-binding protein 1 P02696 RET1_RAT Rattus norvegicus 3 0.7522
Beta-secretase 1 P56817 BACE1_HUMAN Homo sapiens 2 0.7519
Beta-secretase 1 P56817 BACE1_HUMAN Homo sapiens 2 0.7519
Bromodomain-containing protein 4 O60885 BRD4_HUMAN Homo sapiens 2 0.7515
Bromodomain-containing protein 4 O60885 BRD4_HUMAN Homo sapiens 2 0.7515
Casein kinase II subunit alpha' P19784 CSK22_HUMAN Homo sapiens 2 0.7514
Casein kinase II subunit alpha' P19784 CSK22_HUMAN Homo sapiens 2 0.7514
Bromodomain-containing protein 2 P25440 BRD2_HUMAN Homo sapiens 2 0.7510
Bromodomain-containing protein 2 P25440 BRD2_HUMAN Homo sapiens 2 0.7510
3-phosphoinositide-dependent protein kinase 1 O15530 PDPK1_HUMAN Homo sapiens 3 0.7506
3-phosphoinositide-dependent protein kinase 1 O15530 PDPK1_HUMAN Homo sapiens 3 0.7506
Vitamin D(3) 25-hydroxylase C4B644 CPVDH_PSEAH Pseudonocardia autotrophica 3 0.7504
Vitamin D(3) 25-hydroxylase C4B644 CPVDH_PSEAH Pseudonocardia autotrophica 3 0.7504
Fructose-1,6-bisphosphatase 1 P00636 F16P1_PIG Sus scrofa 3 0.7478
Fructose-1,6-bisphosphatase 1 P00636 F16P1_PIG Sus scrofa 3 0.7478
Ras-related protein Ral-B P11234 RALB_HUMAN Homo sapiens 3 0.7458
Ras-related protein Ral-B P11234 RALB_HUMAN Homo sapiens 3 0.7458
Sodium-dependent dopamine transporter Q7K4Y6 DAT_DROME Drosophila melanogaster 2 0.7452
Sodium-dependent dopamine transporter Q7K4Y6 DAT_DROME Drosophila melanogaster 2 0.7452
2,7-dihydroxy-5-methyl-1-naphthoate 7-O-methyltransferase Q84HC8 NCSB1_STRCZ Streptomyces carzinostaticus 2 0.7451
2,7-dihydroxy-5-methyl-1-naphthoate 7-O-methyltransferase Q84HC8 NCSB1_STRCZ Streptomyces carzinostaticus 2 0.7451
Protein LlR18A P52778 L18A_LUPLU Lupinus luteus 3 0.7443
Protein LlR18A P52778 L18A_LUPLU Lupinus luteus 3 0.7443
3',5'-cyclic-AMP phosphodiesterase 4A P27815 PDE4A_HUMAN Homo sapiens 3 0.7443
3',5'-cyclic-AMP phosphodiesterase 4A P27815 PDE4A_HUMAN Homo sapiens 3 0.7443
Aldo-keto reductase family 1 member D1 P51857 AK1D1_HUMAN Homo sapiens 2 0.7433
Aldo-keto reductase family 1 member D1 P51857 AK1D1_HUMAN Homo sapiens 2 0.7433
Steroid Delta-isomerase P07445 SDIS_PSEPU Pseudomonas putida 2 0.7431
Steroid Delta-isomerase P07445 SDIS_PSEPU Pseudomonas putida 2 0.7431
Kynurenine 3-monooxygenase P38169 KMO_YEAST Saccharomyces cerevisiae 2 0.7427
Kynurenine 3-monooxygenase P38169 KMO_YEAST Saccharomyces cerevisiae 2 0.7427
Cytochrome P450 monooxygenase Q5YNS8 Q5YNS8_NOCFA Nocardia farcinica 3 0.7423
Cytochrome P450 monooxygenase Q5YNS8 Q5YNS8_NOCFA Nocardia farcinica 3 0.7423
cAMP-dependent protein kinase catalytic subunit alpha P17612 KAPCA_HUMAN Homo sapiens 3 0.7416
cAMP-dependent protein kinase catalytic subunit alpha P17612 KAPCA_HUMAN Homo sapiens 3 0.7416
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 P04191 AT2A1_RABIT Oryctolagus cuniculus 3 0.7409
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 P04191 AT2A1_RABIT Oryctolagus cuniculus 3 0.7409
Fatty acid-binding protein, liver P80226 FABPL_CHICK Gallus gallus 2 0.7402
Fatty acid-binding protein, liver P80226 FABPL_CHICK Gallus gallus 2 0.7402
Steroid Delta-isomerase P00947 SDIS_COMTE Comamonas testosteroni 3 0.7400
Steroid Delta-isomerase P00947 SDIS_COMTE Comamonas testosteroni 3 0.7400
Abscisic acid receptor PYL9 Q84MC7 PYL9_ARATH Arabidopsis thaliana 2 0.7395
Abscisic acid receptor PYL9 Q84MC7 PYL9_ARATH Arabidopsis thaliana 2 0.7395
Aldo-keto reductase family 1 member C1 Q04828 AK1C1_HUMAN Homo sapiens 2 0.7391
Aldo-keto reductase family 1 member C1 Q04828 AK1C1_HUMAN Homo sapiens 2 0.7391
Peptidyl-prolyl cis-trans isomerase FKBP5 Q13451 FKBP5_HUMAN Homo sapiens 3 0.7386
Aldo-keto reductase family 1 member C2 P52895 AK1C2_HUMAN Homo sapiens 2 0.7386
Peptidyl-prolyl cis-trans isomerase FKBP5 Q13451 FKBP5_HUMAN Homo sapiens 3 0.7386
Aldo-keto reductase family 1 member C2 P52895 AK1C2_HUMAN Homo sapiens 2 0.7386
Aldo-keto reductase family 1 member C2 P52895 AK1C2_HUMAN Homo sapiens 2 0.7370
Aldo-keto reductase family 1 member C2 P52895 AK1C2_HUMAN Homo sapiens 2 0.7370
Ferrochelatase, mitochondrial P22830 HEMH_HUMAN Homo sapiens 3 0.7369
Ferrochelatase, mitochondrial P22830 HEMH_HUMAN Homo sapiens 3 0.7369
Chitinase Q54276 Q54276_SERMA Serratia marcescens 3 0.7369
Chitinase Q54276 Q54276_SERMA Serratia marcescens 3 0.7369
Mitochondrial poly(A) polymerase F1NBW0 F1NBW0_CHICK Gallus gallus 2 0.7368
Mitochondrial poly(A) polymerase F1NBW0 F1NBW0_CHICK Gallus gallus 2 0.7368
Mycinamicin III 3''-O-methyltransferase Q49492 MYCF_MICGR Micromonospora griseorubida 2 0.7359
Mycinamicin III 3''-O-methyltransferase Q49492 MYCF_MICGR Micromonospora griseorubida 2 0.7359
Aldo-keto reductase family 1 member D1 P51857 AK1D1_HUMAN Homo sapiens 3 0.7355
Aldo-keto reductase family 1 member D1 P51857 AK1D1_HUMAN Homo sapiens 3 0.7355
High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A O76083 PDE9A_HUMAN Homo sapiens 2 0.7348
High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A O76083 PDE9A_HUMAN Homo sapiens 2 0.7348
Abscisic acid receptor PYL3 Q9SSM7 PYL3_ARATH Arabidopsis thaliana 2 0.7345
Abscisic acid receptor PYL3 Q9SSM7 PYL3_ARATH Arabidopsis thaliana 2 0.7345
glutaryl-CoA dehydrogenase (ETF) Q3JP94 Q3JP94_BURP1 Burkholderia pseudomallei 2 0.7312
glutaryl-CoA dehydrogenase (ETF) Q3JP94 Q3JP94_BURP1 Burkholderia pseudomallei 2 0.7312
Androgen receptor P10275 ANDR_HUMAN Homo sapiens 3 0.7309
Androgen receptor P10275 ANDR_HUMAN Homo sapiens 3 0.7309
Polymerase acidic protein C3W5S0 C3W5S0_I09A0 Influenza A virus 2 0.7307
Polymerase acidic protein C3W5S0 C3W5S0_I09A0 Influenza A virus 2 0.7307
Casein kinase II subunit alpha P68400 CSK21_HUMAN Homo sapiens 2 0.7303
Casein kinase II subunit alpha P68400 CSK21_HUMAN Homo sapiens 2 0.7303
Bromodomain adjacent to zinc finger domain protein 2B Q9UIF8 BAZ2B_HUMAN Homo sapiens 3 0.7301
Bromodomain adjacent to zinc finger domain protein 2B Q9UIF8 BAZ2B_HUMAN Homo sapiens 3 0.7301
Albumin P02768 ALBU_HUMAN Homo sapiens 3 0.7286
Albumin P02768 ALBU_HUMAN Homo sapiens 3 0.7286
Thymidine kinase P0DTH5 KITH_HHV11 Human herpesvirus 1 3 0.7280
Thymidine kinase P0DTH5 KITH_HHV11 Human herpesvirus 1 3 0.7280
Tetracycline repressor protein class H P51561 TETR8_PASMD Pasteurella multocida 3 0.7278
Tetracycline repressor protein class H P51561 TETR8_PASMD Pasteurella multocida 3 0.7278
Class 10 plant pathogenesis-related protein 2B Q9LLQ2 P102B_LUPLU Lupinus luteus 2 0.7268
Class 10 plant pathogenesis-related protein 2B Q9LLQ2 P102B_LUPLU Lupinus luteus 2 0.7268
Androgen receptor P10275 ANDR_HUMAN Homo sapiens 3 0.7264
Androgen receptor P10275 ANDR_HUMAN Homo sapiens 3 0.7264
CmeR Q7B8P6 Q7B8P6_CAMJU Campylobacter jejuni 2 0.7253
CmeR Q7B8P6 Q7B8P6_CAMJU Campylobacter jejuni 2 0.7253
Pancreatic alpha-amylase P04746 AMYP_HUMAN Homo sapiens 2 0.7251
Pancreatic alpha-amylase P04746 AMYP_HUMAN Homo sapiens 2 0.7251
Vitamin D3 receptor P13053 VDR_RAT Rattus norvegicus 3 0.7248
Vitamin D3 receptor P13053 VDR_RAT Rattus norvegicus 3 0.7248
Acetylcholinesterase P21836 ACES_MOUSE Mus musculus 2 0.7246
Acetylcholinesterase P21836 ACES_MOUSE Mus musculus 2 0.7246
3',5'-cyclic-AMP phosphodiesterase 4D Q08499 PDE4D_HUMAN Homo sapiens 3 0.7240
3',5'-cyclic-AMP phosphodiesterase 4D Q08499 PDE4D_HUMAN Homo sapiens 3 0.7240
Aldo-keto reductase family 1 member B10 O60218 AK1BA_HUMAN Homo sapiens 2 0.7239
Aldo-keto reductase family 1 member B10 O60218 AK1BA_HUMAN Homo sapiens 2 0.7239
Glucan 1,3-beta-glucosidase P29717 EXG1_CANAL Candida albicans 2 0.7228
Glucan 1,3-beta-glucosidase P29717 EXG1_CANAL Candida albicans 2 0.7228
Gastrotropin P51161 FABP6_HUMAN Homo sapiens 3 0.7220
Gastrotropin P51161 FABP6_HUMAN Homo sapiens 3 0.7220
Genome polyprotein Q2YHF0 POLG_DEN4T Dengue virus type 4 3 0.7218
Genome polyprotein Q2YHF0 POLG_DEN4T Dengue virus type 4 3 0.7218
Steroid Delta-isomerase P00947 SDIS_COMTE Comamonas testosteroni 3 0.7211
Steroid Delta-isomerase P00947 SDIS_COMTE Comamonas testosteroni 3 0.7211
Albumin P02768 ALBU_HUMAN Homo sapiens 2 0.7208
Albumin P02768 ALBU_HUMAN Homo sapiens 2 0.7208
Lanosterol 14-alpha-demethylase Q385E8 Q385E8_TRYB2 Trypanosoma brucei brucei 3 0.7201
Lanosterol 14-alpha-demethylase Q385E8 Q385E8_TRYB2 Trypanosoma brucei brucei 3 0.7201
Aldo-keto reductase family 1 member D1 P51857 AK1D1_HUMAN Homo sapiens 2 0.7190
Aldo-keto reductase family 1 member D1 P51857 AK1D1_HUMAN Homo sapiens 2 0.7190
Thymidylate synthase P00469 TYSY_LACCA Lacticaseibacillus casei 3 0.7188
Thymidylate synthase P00469 TYSY_LACCA Lacticaseibacillus casei 3 0.7188
Steroid Delta-isomerase P00947 SDIS_COMTE Comamonas testosteroni 2 0.7181
Steroid Delta-isomerase P00947 SDIS_COMTE Comamonas testosteroni 2 0.7181
cGMP-inhibited 3',5'-cyclic phosphodiesterase 3B Q13370 PDE3B_HUMAN Homo sapiens 3 0.7176
Prostaglandin reductase 2 Q8N8N7 PTGR2_HUMAN Homo sapiens 2 0.7176
Prostaglandin reductase 2 Q8N8N7 PTGR2_HUMAN Homo sapiens 2 0.7176
cGMP-inhibited 3',5'-cyclic phosphodiesterase 3B Q13370 PDE3B_HUMAN Homo sapiens 3 0.7176
3',5'-cyclic-AMP phosphodiesterase 4D Q08499 PDE4D_HUMAN Homo sapiens 3 0.7168
3',5'-cyclic-AMP phosphodiesterase 4D Q08499 PDE4D_HUMAN Homo sapiens 3 0.7168
Heat shock protein HSP 90-alpha P07900 HS90A_HUMAN Homo sapiens 3 0.7165
Heat shock protein HSP 90-alpha P07900 HS90A_HUMAN Homo sapiens 3 0.7165
Photosynthetic reaction center cytochrome c subunit P07173 CYCR_BLAVI Blastochloris viridis 3 0.7164
Photosynthetic reaction center cytochrome c subunit P07173 CYCR_BLAVI Blastochloris viridis 3 0.7164
Troponin C, slow skeletal and cardiac muscles P63316 TNNC1_HUMAN Homo sapiens 2 0.7164
Troponin C, slow skeletal and cardiac muscles P63316 TNNC1_HUMAN Homo sapiens 2 0.7164
3',5'-cyclic-AMP phosphodiesterase 4D Q08499 PDE4D_HUMAN Homo sapiens 3 0.7159
3',5'-cyclic-AMP phosphodiesterase 4D Q08499 PDE4D_HUMAN Homo sapiens 3 0.7159
Putative cytochrome P450 120 Q59990 CP120_SYNY3 Synechocystis sp 3 0.7157
Putative cytochrome P450 120 Q59990 CP120_SYNY3 Synechocystis sp 3 0.7157
Chitinase A Q9AMP1 Q9AMP1_VIBHA Vibrio harveyi 2 0.7156
Norsolorinic acid synthase Q12053 AFLC_ASPPU Aspergillus parasiticus 2 0.7156
Norsolorinic acid synthase Q12053 AFLC_ASPPU Aspergillus parasiticus 2 0.7156
Chitinase A Q9AMP1 Q9AMP1_VIBHA Vibrio harveyi 2 0.7156
Purine nucleoside phosphorylase DeoD-type O34925 DEOD_BACSU Bacillus subtilis 2 0.7153
Purine nucleoside phosphorylase DeoD-type O34925 DEOD_BACSU Bacillus subtilis 2 0.7153
Cyclic GMP-AMP phosphodiesterase SMPDL3A Q92484 ASM3A_HUMAN Homo sapiens 2 0.7151
Cyclic GMP-AMP phosphodiesterase SMPDL3A Q92484 ASM3A_HUMAN Homo sapiens 2 0.7151
Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial Q0QF01 SDHA_PIG Sus scrofa 3 0.7150
Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial Q0QF01 SDHA_PIG Sus scrofa 3 0.7150
High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A O76083 PDE9A_HUMAN Homo sapiens 3 0.7145
High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A O76083 PDE9A_HUMAN Homo sapiens 3 0.7145
Japanin M1MR49 M1MR49_RHIAP Rhipicephalus appendiculatus 3 0.7132
Japanin M1MR49 M1MR49_RHIAP Rhipicephalus appendiculatus 3 0.7132
Carminomycin 4-O-methyltransferase DnrK Q06528 DNRK_STRPE Streptomyces peucetius 2 0.7131
Cyclic nucleotide-binding protein B8FW11 B8FW11_DESHD Desulfitobacterium hafniense 3 0.7131
Retinol dehydratase Q26490 Q26490_SPOFR Spodoptera frugiperda 3 0.7131
Carminomycin 4-O-methyltransferase DnrK Q06528 DNRK_STRPE Streptomyces peucetius 2 0.7131
Retinol dehydratase Q26490 Q26490_SPOFR Spodoptera frugiperda 3 0.7131
Cyclic nucleotide-binding protein B8FW11 B8FW11_DESHD Desulfitobacterium hafniense 3 0.7131
Methylketone synthase I E0YCS2 E0YCS2_SOLHA Solanum habrochaites 2 0.7120
Methylketone synthase I E0YCS2 E0YCS2_SOLHA Solanum habrochaites 2 0.7120
Streptogramin A acetyltransferase P50870 VATD_ENTFC Enterococcus faecium 3 0.7114
Streptogramin A acetyltransferase P50870 VATD_ENTFC Enterococcus faecium 3 0.7114
Acetylcholinesterase P21836 ACES_MOUSE Mus musculus 3 0.7114
Acetylcholinesterase P21836 ACES_MOUSE Mus musculus 3 0.7114
Bromodomain-containing protein 2 P25440 BRD2_HUMAN Homo sapiens 2 0.7113
Bromodomain-containing protein 2 P25440 BRD2_HUMAN Homo sapiens 2 0.7113
Ferrochelatase, mitochondrial P22830 HEMH_HUMAN Homo sapiens 3 0.7112
Ferrochelatase, mitochondrial P22830 HEMH_HUMAN Homo sapiens 3 0.7112
Nuclear receptor subfamily 1 group I member 3 O35627 NR1I3_MOUSE Mus musculus 2 0.7111
Nuclear receptor subfamily 1 group I member 3 O35627 NR1I3_MOUSE Mus musculus 2 0.7111
Basic phospholipase A2 VRV-PL-VIIIa P59071 PA2B8_DABRR Daboia russelii 2 0.7105
Basic phospholipase A2 VRV-PL-VIIIa P59071 PA2B8_DABRR Daboia russelii 2 0.7105
Avidin P02701 AVID_CHICK Gallus gallus 2 0.7101
Avidin P02701 AVID_CHICK Gallus gallus 2 0.7101
Vitamin D-binding protein P02774 VTDB_HUMAN Homo sapiens 2 0.7098
Vitamin D-binding protein P02774 VTDB_HUMAN Homo sapiens 2 0.7098
Ferrochelatase, mitochondrial P22830 HEMH_HUMAN Homo sapiens 2 0.7095
Ferrochelatase, mitochondrial P22830 HEMH_HUMAN Homo sapiens 2 0.7095
Reaction center protein L chain P0C0Y7 RCEH_RHOSH Rhodobacter sphaeroides 3 0.7095
Reaction center protein L chain P0C0Y7 RCEH_RHOSH Rhodobacter sphaeroides 3 0.7095
17-beta-hydroxysteroid dehydrogenase type 1 P14061 DHB1_HUMAN Homo sapiens 2 0.7090
17-beta-hydroxysteroid dehydrogenase type 1 P14061 DHB1_HUMAN Homo sapiens 2 0.7090
Glutamate receptor 2 P19491 GRIA2_RAT Rattus norvegicus 2 0.7081
Glutamate receptor 2 P19491 GRIA2_RAT Rattus norvegicus 2 0.7081
Glucosidase II subunit alpha Q9STC1 Q9STC1_GRALE Gracilariopsis lemaneiformis 3 0.7075
Glucosidase II subunit alpha Q9STC1 Q9STC1_GRALE Gracilariopsis lemaneiformis 3 0.7075
Phenylalanine-4-hydroxylase P00439 PH4H_HUMAN Homo sapiens 2 0.7071
Phenylalanine-4-hydroxylase P00439 PH4H_HUMAN Homo sapiens 2 0.7071
NPC intracellular cholesterol transporter 1 O15118 NPC1_HUMAN Homo sapiens 3 0.7065
NPC intracellular cholesterol transporter 1 O15118 NPC1_HUMAN Homo sapiens 3 0.7065
UTP-monosaccharide-1-phosphate uridylyltransferase D3G6S4 D3G6S4_LEIMA Leishmania major 3 0.7062
UTP-monosaccharide-1-phosphate uridylyltransferase D3G6S4 D3G6S4_LEIMA Leishmania major 3 0.7062
Methionine aminopeptidase 2 P9WK19 MAP12_MYCTU Mycobacterium tuberculosis 3 0.7056
Methionine aminopeptidase 2 P9WK19 MAP12_MYCTU Mycobacterium tuberculosis 3 0.7056
Polyribonucleotide nucleotidyltransferase A7ZS61 PNP_ECO24 Escherichia coli O139:H28 3 0.7049
Polyribonucleotide nucleotidyltransferase A7ZS61 PNP_ECO24 Escherichia coli O139:H28 3 0.7049
Beta-1 adrenergic receptor P07700 ADRB1_MELGA Meleagris gallopavo 3 0.7045
Beta-1 adrenergic receptor P07700 ADRB1_MELGA Meleagris gallopavo 3 0.7045
Sulfotransferase 2B1 O00204 ST2B1_HUMAN Homo sapiens 2 0.7043
Sulfotransferase 2B1 O00204 ST2B1_HUMAN Homo sapiens 2 0.7043
Dihydropteroate synthase Q81VW8 Q81VW8_BACAN Bacillus anthracis 2 0.7042
Dihydropteroate synthase Q81VW8 Q81VW8_BACAN Bacillus anthracis 2 0.7042
NAD-capped RNA hydrolase NudC P32664 NUDC_ECOLI Escherichia coli 3 0.7040
NAD-capped RNA hydrolase NudC P32664 NUDC_ECOLI Escherichia coli 3 0.7040
Polymerase acidic protein C3W5S0 C3W5S0_I09A0 Influenza A virus 2 0.7038
Polymerase acidic protein C3W5S0 C3W5S0_I09A0 Influenza A virus 2 0.7038
4-diphosphocytidyl-2-C-methyl-D-erythritol kinase O67060 ISPE_AQUAE Aquifex aeolicus 3 0.7029
4-diphosphocytidyl-2-C-methyl-D-erythritol kinase O67060 ISPE_AQUAE Aquifex aeolicus 3 0.7029
Acetolactate synthase, chloroplastic P17597 ILVB_ARATH Arabidopsis thaliana 2 0.7028
Retinol-binding protein 4 P18902 RET4_BOVIN Bos taurus 2 0.7028
Casein kinase II subunit alpha P28523 CSK2A_MAIZE Zea mays 3 0.7028
Retinol-binding protein 4 P18902 RET4_BOVIN Bos taurus 2 0.7028
Casein kinase II subunit alpha P28523 CSK2A_MAIZE Zea mays 3 0.7028
Acetolactate synthase, chloroplastic P17597 ILVB_ARATH Arabidopsis thaliana 2 0.7028
Photosynthetic reaction center cytochrome c subunit P07173 CYCR_BLAVI Blastochloris viridis 3 0.7022
Photosynthetic reaction center cytochrome c subunit P07173 CYCR_BLAVI Blastochloris viridis 3 0.7022
Toxoflavin degrading enzyme E3SET7 E3SET7_PAEPO Paenibacillus polymyxa 2 0.7020
Toxoflavin degrading enzyme E3SET7 E3SET7_PAEPO Paenibacillus polymyxa 2 0.7020
Holliday junction branch migration complex subunit RuvB Q9PMT7 RUVB_CAMJE Campylobacter jejuni subsp. jejuni serotype O:2 2 0.7015
Holliday junction branch migration complex subunit RuvB Q9PMT7 RUVB_CAMJE Campylobacter jejuni subsp. jejuni serotype O:2 2 0.7015
Prolyl tripeptidyl peptidase Q7MUW6 PTP_PORGI Porphyromonas gingivalis 2 0.7010
Prolyl tripeptidyl peptidase Q7MUW6 PTP_PORGI Porphyromonas gingivalis 2 0.7010
Thymidine kinase P0DTH5 KITH_HHV11 Human herpesvirus 1 2 0.7001
Rhodopsin P02699 OPSD_BOVIN Bos taurus 3 0.7001
Rhodopsin P02699 OPSD_BOVIN Bos taurus 3 0.7001
Thymidine kinase P0DTH5 KITH_HHV11 Human herpesvirus 1 2 0.7001
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 P04191 AT2A1_RABIT Oryctolagus cuniculus 3 0.7000
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 P04191 AT2A1_RABIT Oryctolagus cuniculus 3 0.7000

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