ANPDB

Select a section from the left sidebar

Aposcopolamine

Family: Plantae - Solanaceae
Kingdom: Plantae
Class: Alkaloid

Canonical Smiles	CN1C2CC(CC1C1C2O1)OC(=O)C(=C)c1ccccc1
InChI	InChI=1S/C17H19NO3/c1-10(11-6-4-3-5-7-11)17(19)20-12-8-13-15-16(21-15)14(9-12)18(13)2/h3-7,12-16H,1,8-9H2,2H3
InChIKey	JJNVDCBKBUSUII-UHFFFAOYSA-N
Formula	C₁₇H₁₉NO₃
HBA	4
HBD	0
MW	285.34
Rotatable Bonds	3
TPSA	42.07
LogP	1.86
Number Rings	4
Number Aromatic Rings	1
Heavy Atom Count	21
Formal Charge	0
Fraction CSP3	0.47
Exact Mass	285.14
Number of Lipinski Rule Violations	0

#	Species	Family	Kingdom	NCBI Taxonomy ID
1	Datura stramonium	Solanaceae	Plantae	4076

Showing of synonyms

El Bazaoui A, Bellimam MA, et al. (2011). Nine new tropane alkaloids from Datura stramonium L. identified by GC/MS. Fitoterapia,2011,82(2),193-197. [View] [PubMed]

Pubchem: 4486617

Nmrshiftdb2: 70080947

CPRiL: 413079

SMILES: c1ccccc1C(=C)C(=O)OC(CC2N3)CC3C(O4)C24

Level: 1

Mol. Weight: 285.34 g/mol

SMILES: C12C(O2)C3CCCC1N3

Level: 0

Mol. Weight: 285.34 g/mol

SMILES: c1ccccc1

Level: 0

Mol. Weight: 285.34 g/mol

No bioactivities available.

Absorption

Caco-2 (logPapp): -4.84
Human Oral Bioavailability 20%: Bioavailable
Human Intestinal Absorption: Absorbed
Madin-Darby Canine Kidney: -4.49
Human Oral Bioavailability 50%: Bioavailable
P-Glycoprotein Inhibitor: Non-Inhibitor
P-Glycoprotein Substrate: Non-Substrate
Skin Permeability: -2.43

Distribution

Blood-Brain Barrier (CNS): -
Blood-Brain Barrier: Penetrable
Fraction Unbound (Human): 0.29
Plasma Protein Binding: 2.33
Steady State Volume of Distribution: -

Metabolism

Breast Cancer Resistance Protein: Non-Inhibitor
CYP 1A2 Inhibitor: Non-Inhibitor
CYP 1A2 Substrate: Non-Substrate
CYP 2C19 Inhibitor: Non-Inhibitor
CYP 2C19 Substrate: Non-Substrate
CYP 2C9 Inhibitor: Non-Inhibitor
CYP 2C9 Substrate: Non-Substrate
CYP 2D6 Inhibitor: Non-Inhibitor
CYP 2D6 Substrate: Substrate
CYP 3A4 Inhibitor: Non-Inhibitor
CYP 3A4 Substrate: Substrate
OATP1B1: Non-Inhibitor
OATP1B3: Non-Inhibitor

Excretion

Clearance: 15.74
Organic Cation Transporter 2: Inhibitor
Half-Life of Drug: -

Toxicity

AMES Mutagenesis: Safe
Avian: Safe
Bee: Toxic
Bioconcentration Factor: 1.19
Biodegradation: Safe
Carcinogenesis: Safe
Crustacean: Toxic
Liver Injury I (DILI): Safe
Eye Corrosion: Safe
Eye Irritation: Safe
Maximum Tolerated Dose: -2.2
Liver Injury II: Safe
hERG Blockers: Safe
Daphnia Maga: 7.16
Micronucleos: Toxic
NR-AhR: Safe
NR-AR: Safe
NR-AR-LBD: Safe
NR-Aromatase: Safe
NR-ER: Safe
NR-ER-LBD: Safe
NR-GR: Safe
NR-PPAR-gamma: Safe
NR-TR: Safe
T. Pyriformis: 4.43
Rat (Acute): 2.99
Rat (Chronic Oral): 0.9
Fathead Minnow: 4.4
Respiratory Disease: Toxic
Skin Sensitisation: Toxic
SR-ARE: Safe
SR-ATAD5: Safe
SR-HSE: Safe
SR-MMP: Safe
SR-p53: Safe

General Properties

Boiling Point: 334.57
Hydration Free Energy: -7.39
Log(D) at pH=7.4: 1.67
Log(P): 2.32
Log S: -1.72
Log(Vapor Pressure): -6.39
Melting Point: 73.12
pKa Acid: 5.31
pKa Basic: 7.63

Protein Name	UniProt ID	Entry Name	Species	#Pharmacophore Points	Probability (0.7 ≤ Tversky Score ≤ 1.0)
3',5'-cyclic-AMP phosphodiesterase 4D	Q08499	PDE4D_HUMAN	Homo sapiens	3	0.9457
3',5'-cyclic-AMP phosphodiesterase 4D	Q08499	PDE4D_HUMAN	Homo sapiens	3	0.9457
Tetracycline repressor protein class D	P0ACT4	TETR4_ECOLX	Escherichia coli	3	0.9445
Tetracycline repressor protein class D	P0ACT4	TETR4_ECOLX	Escherichia coli	3	0.9445
3',5'-cyclic-AMP phosphodiesterase 4D	Q08499	PDE4D_HUMAN	Homo sapiens	3	0.9194
3',5'-cyclic-AMP phosphodiesterase 4D	Q08499	PDE4D_HUMAN	Homo sapiens	3	0.9194
Phytohormone-binding protein CSBP	A0A1S3THR8	PHBP_VIGRR	Vigna radiata var. radiata	3	0.9179
Phytohormone-binding protein CSBP	A0A1S3THR8	PHBP_VIGRR	Vigna radiata var. radiata	3	0.9179
Steroid C26-monooxygenase	P9WPP1	CP125_MYCTU	Mycobacterium tuberculosis	3	0.9169
Steroid C26-monooxygenase	P9WPP1	CP125_MYCTU	Mycobacterium tuberculosis	3	0.9169
Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial	Q33862	Q33862_ASCSU	Ascaris suum	3	0.8911
Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial	Q33862	Q33862_ASCSU	Ascaris suum	3	0.8911
Albumin	P02768	ALBU_HUMAN	Homo sapiens	3	0.8869
Albumin	P02768	ALBU_HUMAN	Homo sapiens	3	0.8869
Histone deacetylase 8	Q9BY41	HDAC8_HUMAN	Homo sapiens	3	0.8857
Histone deacetylase 8	Q9BY41	HDAC8_HUMAN	Homo sapiens	3	0.8857
Neocarzinostatin	P0A3R9	NCZS_STRCZ	Streptomyces carzinostaticus	3	0.8736
Neocarzinostatin	P0A3R9	NCZS_STRCZ	Streptomyces carzinostaticus	3	0.8736
HTH-type transcriptional regulator EthR	P9WMC1	ETHR_MYCTU	Mycobacterium tuberculosis	3	0.8726
HTH-type transcriptional regulator EthR	P9WMC1	ETHR_MYCTU	Mycobacterium tuberculosis	3	0.8726
3-ketosteroid dehydrogenase	Q9RA02	Q9RA02_RHOER	Rhodococcus erythropolis	3	0.8606
3-ketosteroid dehydrogenase	Q9RA02	Q9RA02_RHOER	Rhodococcus erythropolis	3	0.8606
Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial	Q0QF01	SDHA_PIG	Sus scrofa	3	0.8601
Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial	Q0QF01	SDHA_PIG	Sus scrofa	3	0.8601
Trichothecene 15-O-acetyltransferase TRI3	Q9C1B7	TRI3_FUSSP	Fusarium sporotrichioides	3	0.8502
Trichothecene 15-O-acetyltransferase TRI3	Q9C1B7	TRI3_FUSSP	Fusarium sporotrichioides	3	0.8502
Steroid Delta-isomerase	P00947	SDIS_COMTE	Comamonas testosteroni	3	0.8417
Steroid Delta-isomerase	P00947	SDIS_COMTE	Comamonas testosteroni	3	0.8417
Bifunctional epoxide hydrolase 2	P34913	HYES_HUMAN	Homo sapiens	3	0.8316
Bifunctional epoxide hydrolase 2	P34913	HYES_HUMAN	Homo sapiens	3	0.8316
Endothiapepsin	P11838	CARP_CRYPA	Cryphonectria parasitica	3	0.8228
Endothiapepsin	P11838	CARP_CRYPA	Cryphonectria parasitica	3	0.8228
Mycocyclosin synthase	P9WPP7	CP121_MYCTU	Mycobacterium tuberculosis	2	0.8194
Mycocyclosin synthase	P9WPP7	CP121_MYCTU	Mycobacterium tuberculosis	2	0.8194
Succinate dehydrogenase flavoprotein subunit	P0AC41	SDHA_ECOLI	Escherichia coli	3	0.8187
Succinate dehydrogenase flavoprotein subunit	P0AC41	SDHA_ECOLI	Escherichia coli	3	0.8187
AcsD	Q93AT8	Q93AT8_DICCH	Dickeya chrysanthemi	3	0.8134
AcsD	Q93AT8	Q93AT8_DICCH	Dickeya chrysanthemi	3	0.8134
Basic phospholipase A2 VRV-PL-VIIIa	P59071	PA2B8_DABRR	Daboia russelii	2	0.8053
Basic phospholipase A2 VRV-PL-VIIIa	P59071	PA2B8_DABRR	Daboia russelii	2	0.8053
Class B acid phosphatase	Q540U1	APHA_SALTM	Salmonella typhimurium	2	0.8051
Class B acid phosphatase	Q540U1	APHA_SALTM	Salmonella typhimurium	2	0.8051
Histone deacetylase 8	Q9BY41	HDAC8_HUMAN	Homo sapiens	3	0.7989
Histone deacetylase 8	Q9BY41	HDAC8_HUMAN	Homo sapiens	3	0.7989
cGMP-dependent protein kinase 2	Q13237	KGP2_HUMAN	Homo sapiens	3	0.7986
cGMP-dependent protein kinase 2	Q13237	KGP2_HUMAN	Homo sapiens	3	0.7986
Fibroblast growth factor receptor 1	P11362	FGFR1_HUMAN	Homo sapiens	3	0.7983
Fibroblast growth factor receptor 1	P11362	FGFR1_HUMAN	Homo sapiens	3	0.7983
MAP kinase-activated protein kinase 2	P49137	MAPK2_HUMAN	Homo sapiens	3	0.7853
MAP kinase-activated protein kinase 2	P49137	MAPK2_HUMAN	Homo sapiens	3	0.7853
Steroid Delta-isomerase	P07445	SDIS_PSEPU	Pseudomonas putida	2	0.7839
Steroid Delta-isomerase	P07445	SDIS_PSEPU	Pseudomonas putida	2	0.7839
Histone deacetylase 8	Q9BY41	HDAC8_HUMAN	Homo sapiens	2	0.7792
Histone deacetylase 8	Q9BY41	HDAC8_HUMAN	Homo sapiens	2	0.7792
cAMP-dependent protein kinase type I-alpha regulatory subunit	P00514	KAP0_BOVIN	Bos taurus	3	0.7724
cAMP-dependent protein kinase type I-alpha regulatory subunit	P00514	KAP0_BOVIN	Bos taurus	3	0.7724
Beta-1 adrenergic receptor	P07700	ADRB1_MELGA	Meleagris gallopavo	2	0.7722
Beta-1 adrenergic receptor	P07700	ADRB1_MELGA	Meleagris gallopavo	2	0.7722
Glucan 1,3-beta-glucosidase	P29717	EXG1_CANAL	Candida albicans	2	0.7635
Glucan 1,3-beta-glucosidase	P29717	EXG1_CANAL	Candida albicans	2	0.7635
HTH-type transcriptional regulator EthR	P9WMC1	ETHR_MYCTU	Mycobacterium tuberculosis	3	0.7634
HTH-type transcriptional regulator EthR	P9WMC1	ETHR_MYCTU	Mycobacterium tuberculosis	3	0.7634
Estrogen receptor	P03372	ESR1_HUMAN	Homo sapiens	2	0.7629
Estrogen receptor	P03372	ESR1_HUMAN	Homo sapiens	2	0.7629
Succinate dehydrogenase flavoprotein subunit	P0AC41	SDHA_ECOLI	Escherichia coli	3	0.7612
Succinate dehydrogenase flavoprotein subunit	P0AC41	SDHA_ECOLI	Escherichia coli	3	0.7612
Heat shock protein HSP 90-alpha	P07900	HS90A_HUMAN	Homo sapiens	2	0.7600
Heat shock protein HSP 90-alpha	P07900	HS90A_HUMAN	Homo sapiens	2	0.7600
Adenosine kinase	Q9TVW2	ADK_TOXGO	Toxoplasma gondii	3	0.7595
Pheromone-binding protein ASP1	Q9U9J6	Q9U9J6_APIME	Apis mellifera	2	0.7595
Adenosine kinase	Q9TVW2	ADK_TOXGO	Toxoplasma gondii	3	0.7595
Pheromone-binding protein ASP1	Q9U9J6	Q9U9J6_APIME	Apis mellifera	2	0.7595
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1	P04191	AT2A1_RABIT	Oryctolagus cuniculus	2	0.7576
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1	P04191	AT2A1_RABIT	Oryctolagus cuniculus	2	0.7576
Death-associated protein kinase 1	P53355	DAPK1_HUMAN	Homo sapiens	3	0.7562
Death-associated protein kinase 1	P53355	DAPK1_HUMAN	Homo sapiens	3	0.7562
Tetracycline repressor protein class D	P0ACT4	TETR4_ECOLX	Escherichia coli	3	0.7559
Tetracycline repressor protein class D	P0ACT4	TETR4_ECOLX	Escherichia coli	3	0.7559
Beta-1 adrenergic receptor	P07700	ADRB1_MELGA	Meleagris gallopavo	2	0.7558
Beta-1 adrenergic receptor	P07700	ADRB1_MELGA	Meleagris gallopavo	2	0.7558
Endothiapepsin	P11838	CARP_CRYPA	Cryphonectria parasitica	2	0.7540
Endothiapepsin	P11838	CARP_CRYPA	Cryphonectria parasitica	2	0.7540
Gag-Pol polyprotein	P03367	POL_HV1BR	Human immunodeficiency virus type 1 group M subtype B	2	0.7522
Gag-Pol polyprotein	P03367	POL_HV1BR	Human immunodeficiency virus type 1 group M subtype B	2	0.7522
Vitamin D3 dihydroxylase	P18326	CPXE_STRGO	Streptomyces griseolus	3	0.7510
Vitamin D3 dihydroxylase	P18326	CPXE_STRGO	Streptomyces griseolus	3	0.7510
Glucan 1,3-beta-glucosidase	P29717	EXG1_CANAL	Candida albicans	2	0.7506
Glucan 1,3-beta-glucosidase	P29717	EXG1_CANAL	Candida albicans	2	0.7506
Aldo-keto reductase family 1 member C3	P42330	AK1C3_HUMAN	Homo sapiens	2	0.7497
Aldo-keto reductase family 1 member C3	P42330	AK1C3_HUMAN	Homo sapiens	2	0.7497
Casein kinase II subunit alpha	P28523	CSK2A_MAIZE	Zea mays	3	0.7469
Casein kinase II subunit alpha	P28523	CSK2A_MAIZE	Zea mays	3	0.7469
Genome polyprotein	P26663	POLG_HCVBK	Hepatitis C virus genotype 1b	3	0.7467
Genome polyprotein	P26663	POLG_HCVBK	Hepatitis C virus genotype 1b	3	0.7467
Purine nucleoside phosphorylase DeoD-type	O34925	DEOD_BACSU	Bacillus subtilis	2	0.7444
Purine nucleoside phosphorylase DeoD-type	O34925	DEOD_BACSU	Bacillus subtilis	2	0.7444
Probable NDP-rhamnosyltransferase	Q9ALM8	Q9ALM8_SACSN	Saccharopolyspora spinosa	2	0.7430
Probable NDP-rhamnosyltransferase	Q9ALM8	Q9ALM8_SACSN	Saccharopolyspora spinosa	2	0.7430
Vitamin D3 dihydroxylase	P18326	CPXE_STRGO	Streptomyces griseolus	3	0.7421
Vitamin D3 dihydroxylase	P18326	CPXE_STRGO	Streptomyces griseolus	3	0.7421
Endothiapepsin	P11838	CARP_CRYPA	Cryphonectria parasitica	2	0.7409
Beta-secretase 1	P56817	BACE1_HUMAN	Homo sapiens	2	0.7409
Endothiapepsin	P11838	CARP_CRYPA	Cryphonectria parasitica	2	0.7409
Beta-secretase 1	P56817	BACE1_HUMAN	Homo sapiens	2	0.7409
Aldo-keto reductase family 1 member C3	P42330	AK1C3_HUMAN	Homo sapiens	2	0.7399
Aldo-keto reductase family 1 member C3	P42330	AK1C3_HUMAN	Homo sapiens	2	0.7399
Purine nucleoside phosphorylase DeoD-type	P0ABP9	DEOD_ECO57	Escherichia coli O157:H7	2	0.7391
Purine nucleoside phosphorylase DeoD-type	P0ABP9	DEOD_ECO57	Escherichia coli O157:H7	2	0.7391
Stromelysin-1	P08254	MMP3_HUMAN	Homo sapiens	2	0.7383
Stromelysin-1	P08254	MMP3_HUMAN	Homo sapiens	2	0.7383
Cytidine and deoxycytidylate deaminase zinc-binding region	Q82Y41	Q82Y41_NITEU	Nitrosomonas europaea	3	0.7378
Cytidine and deoxycytidylate deaminase zinc-binding region	Q82Y41	Q82Y41_NITEU	Nitrosomonas europaea	3	0.7378
Lethal factor	P15917	LEF_BACAN	Bacillus anthracis	2	0.7369
Lethal factor	P15917	LEF_BACAN	Bacillus anthracis	2	0.7369
Fumarate reductase subunit D	P0A8Q3	FRDD_ECOLI	Escherichia coli	2	0.7364
Fumarate reductase subunit D	P0A8Q3	FRDD_ECOLI	Escherichia coli	2	0.7364
2-phospho-L-lactate transferase	Q8PVT6	COFD_METMA	Methanosarcina mazei	2	0.7349
2-phospho-L-lactate transferase	Q8PVT6	COFD_METMA	Methanosarcina mazei	2	0.7349
Endothiapepsin	P11838	CARP_CRYPA	Cryphonectria parasitica	2	0.7344
Endothiapepsin	P11838	CARP_CRYPA	Cryphonectria parasitica	2	0.7344
Death-associated protein kinase 1	P53355	DAPK1_HUMAN	Homo sapiens	3	0.7338
Chloramphenicol acetyltransferase	P62577	CAT_ECOLX	Escherichia coli	2	0.7338
Death-associated protein kinase 1	P53355	DAPK1_HUMAN	Homo sapiens	3	0.7338
Chloramphenicol acetyltransferase	P62577	CAT_ECOLX	Escherichia coli	2	0.7338
Flavoredoxin	Q72HI0	Q72HI0_THET2	Thermus thermophilus	2	0.7336
Flavoredoxin	Q72HI0	Q72HI0_THET2	Thermus thermophilus	2	0.7336
Cyclic nucleotide-binding domain-containing protein	E0RR11	E0RR11_SPITD	Spirochaeta thermophila	3	0.7333
Cyclic nucleotide-binding domain-containing protein	E0RR11	E0RR11_SPITD	Spirochaeta thermophila	3	0.7333
Metallo-beta-lactamase type 2	C7C422	BLAN1_KLEPN	Klebsiella pneumoniae	2	0.7333
Metallo-beta-lactamase type 2	C7C422	BLAN1_KLEPN	Klebsiella pneumoniae	2	0.7333
Mycinamicin III 3''-O-methyltransferase	Q49492	MYCF_MICGR	Micromonospora griseorubida	2	0.7332
Mycinamicin III 3''-O-methyltransferase	Q49492	MYCF_MICGR	Micromonospora griseorubida	2	0.7332
Thermolysin	P00800	THER_BACTH	Bacillus thermoproteolyticus	2	0.7327
Thermolysin	P00800	THER_BACTH	Bacillus thermoproteolyticus	2	0.7327
1-deoxy-D-xylulose 5-phosphate reductoisomerase	P45568	DXR_ECOLI	Escherichia coli	2	0.7316
1-deoxy-D-xylulose 5-phosphate reductoisomerase	P45568	DXR_ECOLI	Escherichia coli	2	0.7316
Beta-secretase 1	P56817	BACE1_HUMAN	Homo sapiens	2	0.7312
Beta-secretase 1	P56817	BACE1_HUMAN	Homo sapiens	2	0.7312
HTH-type transcriptional regulator EthR	P9WMC1	ETHR_MYCTU	Mycobacterium tuberculosis	2	0.7304
HTH-type transcriptional regulator EthR	P9WMC1	ETHR_MYCTU	Mycobacterium tuberculosis	2	0.7304
Bifunctional epoxide hydrolase 2	P34913	HYES_HUMAN	Homo sapiens	2	0.7299
Bifunctional epoxide hydrolase 2	P34913	HYES_HUMAN	Homo sapiens	2	0.7299
Prothrombin	P00734	THRB_HUMAN	Homo sapiens	2	0.7295
Prothrombin	P00734	THRB_HUMAN	Homo sapiens	2	0.7295
Tetracycline repressor protein class D	P0ACT4	TETR4_ECOLX	Escherichia coli	3	0.7282
Tetracycline repressor protein class D	P0ACT4	TETR4_ECOLX	Escherichia coli	3	0.7282
Carbonic anhydrase 1	P00915	CAH1_HUMAN	Homo sapiens	2	0.7275
Carbonic anhydrase 1	P00915	CAH1_HUMAN	Homo sapiens	2	0.7275
Mycinamicin III 3''-O-methyltransferase	Q49492	MYCF_MICGR	Micromonospora griseorubida	2	0.7272
Mycinamicin III 3''-O-methyltransferase	Q49492	MYCF_MICGR	Micromonospora griseorubida	2	0.7272
Acetyl-CoA carboxylase 2	O00763	ACACB_HUMAN	Homo sapiens	3	0.7254
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1	P04191	AT2A1_RABIT	Oryctolagus cuniculus	3	0.7254
Acetyl-CoA carboxylase 2	O00763	ACACB_HUMAN	Homo sapiens	3	0.7254
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1	P04191	AT2A1_RABIT	Oryctolagus cuniculus	3	0.7254
Liver carboxylesterase 1	P23141	EST1_HUMAN	Homo sapiens	2	0.7242
Liver carboxylesterase 1	P23141	EST1_HUMAN	Homo sapiens	2	0.7242
Cytochrome P450 3A4	P08684	CP3A4_HUMAN	Homo sapiens	3	0.7239
Cytochrome P450 3A4	P08684	CP3A4_HUMAN	Homo sapiens	3	0.7239
Prothrombin	P00734	THRB_HUMAN	Homo sapiens	2	0.7237
Prothrombin	P00734	THRB_HUMAN	Homo sapiens	2	0.7237
Sulfide-quinone reductase	B7JBP8	SQRD_ACIF2	Acidithiobacillus ferrooxidans)	2	0.7231
Sulfide-quinone reductase	B7JBP8	SQRD_ACIF2	Acidithiobacillus ferrooxidans)	2	0.7231
Retinoic acid receptor RXR-alpha	P19793	RXRA_HUMAN	Homo sapiens	2	0.7229
Retinoic acid receptor RXR-alpha	P19793	RXRA_HUMAN	Homo sapiens	2	0.7229
3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase	P19992	HSD_STREX	Streptomyces exfoliatus	2	0.7227
3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase	P19992	HSD_STREX	Streptomyces exfoliatus	2	0.7227
F420-dependent methylenetetrahydromethanopterin dehydrogenase	P94951	MTD_METKA	Methanopyrus kandleri	2	0.7215
F420-dependent methylenetetrahydromethanopterin dehydrogenase	P94951	MTD_METKA	Methanopyrus kandleri	2	0.7215
Nitric oxide synthase, inducible	P35228	NOS2_HUMAN	Homo sapiens	2	0.7214
Nitric oxide synthase, inducible	P35228	NOS2_HUMAN	Homo sapiens	2	0.7214
Soluble acetylcholine receptor	Q8WSF8	Q8WSF8_APLCA	Aplysia californica	3	0.7209
Soluble acetylcholine receptor	Q8WSF8	Q8WSF8_APLCA	Aplysia californica	3	0.7209
Prothrombin	P00734	THRB_HUMAN	Homo sapiens	2	0.7206
Prothrombin	P00734	THRB_HUMAN	Homo sapiens	2	0.7206
Chitinase	Q54276	Q54276_SERMA	Serratia marcescens	2	0.7196
Chitinase	Q54276	Q54276_SERMA	Serratia marcescens	2	0.7196
Coagulation factor X	P00742	FA10_HUMAN	Homo sapiens	2	0.7173
Coagulation factor X	P00742	FA10_HUMAN	Homo sapiens	2	0.7173
Acetylcholinesterase	P21836	ACES_MOUSE	Mus musculus	2	0.7173
Acetylcholinesterase	P21836	ACES_MOUSE	Mus musculus	2	0.7173
Bis(5'-adenosyl)-triphosphatase	P49789	FHIT_HUMAN	Homo sapiens	2	0.7171
Bis(5'-adenosyl)-triphosphatase	P49789	FHIT_HUMAN	Homo sapiens	2	0.7171
D-aminoacyl-tRNA deacylase	Q8IIS0	DTD_PLAF7	Plasmodium falciparum	2	0.7170
D-aminoacyl-tRNA deacylase	Q8IIS0	DTD_PLAF7	Plasmodium falciparum	2	0.7170
Gag-Pol polyprotein	P03369	POL_HV1A2	Human immunodeficiency virus type 1 group M subtype B	2	0.7169
Gag-Pol polyprotein	P03369	POL_HV1A2	Human immunodeficiency virus type 1 group M subtype B	2	0.7169
Tetracycline repressor protein class D	P0ACT4	TETR4_ECOLX	Escherichia coli	3	0.7164
Tetracycline repressor protein class D	P0ACT4	TETR4_ECOLX	Escherichia coli	3	0.7164
Endothiapepsin	P11838	CARP_CRYPA	Cryphonectria parasitica	2	0.7162
Endothiapepsin	P11838	CARP_CRYPA	Cryphonectria parasitica	2	0.7162
Tetracycline repressor protein class D	P0ACT4	TETR4_ECOLX	Escherichia coli	3	0.7159
Tetracycline repressor protein class D	P0ACT4	TETR4_ECOLX	Escherichia coli	3	0.7159
2',3'-cyclic-nucleotide 3'-phosphodiesterase	P16330	CN37_MOUSE	Mus musculus	2	0.7151
2',3'-cyclic-nucleotide 3'-phosphodiesterase	P16330	CN37_MOUSE	Mus musculus	2	0.7151
Diamine acetyltransferase 1	P21673	SAT1_HUMAN	Homo sapiens	2	0.7138
Diamine acetyltransferase 1	P21673	SAT1_HUMAN	Homo sapiens	2	0.7138
L-lactate dehydrogenase A chain	P04642	LDHA_RAT	Rattus norvegicus	2	0.7134
L-lactate dehydrogenase A chain	P04642	LDHA_RAT	Rattus norvegicus	2	0.7134
UDP-N-acetylbacillosamine N-acetyltransferase	Q0P9D1	PGLD_CAMJE	Campylobacter jejuni subsp. jejuni serotype O:2	3	0.7133
UDP-N-acetylbacillosamine N-acetyltransferase	Q0P9D1	PGLD_CAMJE	Campylobacter jejuni subsp. jejuni serotype O:2	3	0.7133
Ferrochelatase, mitochondrial	P22830	HEMH_HUMAN	Homo sapiens	2	0.7128
Ferrochelatase, mitochondrial	P22830	HEMH_HUMAN	Homo sapiens	2	0.7128
Acidic phospholipase A2 3	P60045	PA2A3_NAJSG	Naja sagittifera	2	0.7124
Acidic phospholipase A2 3	P60045	PA2A3_NAJSG	Naja sagittifera	2	0.7124
Death-associated protein kinase 1	P53355	DAPK1_HUMAN	Homo sapiens	3	0.7116
Death-associated protein kinase 1	P53355	DAPK1_HUMAN	Homo sapiens	3	0.7116
Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase	Q9TQS6	DHDH_MACFA	Macaca fascicularis	2	0.7113
Tetracycline repressor protein class D	P0ACT4	TETR4_ECOLX	Escherichia coli	2	0.7113
Tetracycline repressor protein class D	P0ACT4	TETR4_ECOLX	Escherichia coli	2	0.7113
Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase	Q9TQS6	DHDH_MACFA	Macaca fascicularis	2	0.7113
Tetracycline repressor protein class D	P0ACT4	TETR4_ECOLX	Escherichia coli	3	0.7110
Tetracycline repressor protein class D	P0ACT4	TETR4_ECOLX	Escherichia coli	3	0.7110
Prothrombin	P00734	THRB_HUMAN	Homo sapiens	2	0.7106
Prothrombin	P00734	THRB_HUMAN	Homo sapiens	2	0.7106
Regulatory protein SdiA	P07026	SDIA_ECOLI	Escherichia coli	3	0.7105
Regulatory protein SdiA	P07026	SDIA_ECOLI	Escherichia coli	3	0.7105
ABC-type polar amino acid transport system, ATPase component	Q8RCC2	Q8RCC2_CALS4	Caldanaerobacter subterraneus subsp. tengcongensis	2	0.7102
ABC-type polar amino acid transport system, ATPase component	Q8RCC2	Q8RCC2_CALS4	Caldanaerobacter subterraneus subsp. tengcongensis	2	0.7102
Cyclic nucleotide-gated potassium channel mll3241	Q98GN8	CNGK1_RHILO	Mesorhizobium japonicum)	3	0.7093
Cyclic nucleotide-gated potassium channel mll3241	Q98GN8	CNGK1_RHILO	Mesorhizobium japonicum)	3	0.7093
Phenylpyruvate C(3)-methyltransferase	Q643C8	MPPJ_STRHY	Streptomyces hygroscopicus	2	0.7088
Phenylpyruvate C(3)-methyltransferase	Q643C8	MPPJ_STRHY	Streptomyces hygroscopicus	2	0.7088
Glycogen phosphorylase, muscle form	P00489	PYGM_RABIT	Oryctolagus cuniculus	2	0.7087
Glycogen phosphorylase, muscle form	P00489	PYGM_RABIT	Oryctolagus cuniculus	2	0.7087
Tetracycline repressor protein class D	P0ACT4	TETR4_ECOLX	Escherichia coli	2	0.7073
Tetracycline repressor protein class D	P0ACT4	TETR4_ECOLX	Escherichia coli	2	0.7073
Glutamate receptor 2	P19491	GRIA2_RAT	Rattus norvegicus	2	0.7065
Glutamate receptor 2	P19491	GRIA2_RAT	Rattus norvegicus	2	0.7065
Snake venom metalloproteinase atrolysin-D	P15167	VM1AD_CROAT	Crotalus atrox	2	0.7064
Snake venom metalloproteinase atrolysin-D	P15167	VM1AD_CROAT	Crotalus atrox	2	0.7064
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial	Q15119	PDK2_HUMAN	Homo sapiens	3	0.7057
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial	Q15119	PDK2_HUMAN	Homo sapiens	3	0.7057
Muconolactone Delta-isomerase	Q8G9L0	Q8G9L0_RHOOP	Rhodococcus opacus	2	0.7056
Muconolactone Delta-isomerase	Q8G9L0	Q8G9L0_RHOOP	Rhodococcus opacus	2	0.7056
Alanine racemase	Q180W0	Q180W0_CLOD6	Clostridioides difficile	2	0.7054
Alanine racemase	Q180W0	Q180W0_CLOD6	Clostridioides difficile	2	0.7054
Glycogen synthase kinase-3 beta	P49841	GSK3B_HUMAN	Homo sapiens	2	0.7050
Glycogen synthase kinase-3 beta	P49841	GSK3B_HUMAN	Homo sapiens	2	0.7050
Unconventional myosin-Va	Q02440	MYO5A_CHICK	Gallus gallus	2	0.7044
Unconventional myosin-Va	Q02440	MYO5A_CHICK	Gallus gallus	2	0.7044
Single-stranded-DNA-specific exonuclease RecJ	D0EM60	D0EM60_DEIRD	Deinococcus radiodurans	2	0.7036
Single-stranded-DNA-specific exonuclease RecJ	D0EM60	D0EM60_DEIRD	Deinococcus radiodurans	2	0.7036
cAMP-dependent protein kinase type II-beta regulatory subunit	P12369	KAP3_RAT	Rattus norvegicus	3	0.7031
cAMP-dependent protein kinase type II-beta regulatory subunit	P12369	KAP3_RAT	Rattus norvegicus	3	0.7031
Urokinase-type plasminogen activator	P00749	UROK_HUMAN	Homo sapiens	2	0.7029
Urokinase-type plasminogen activator	P00749	UROK_HUMAN	Homo sapiens	2	0.7029
Purine nucleoside phosphorylase	Q8I3X4	Q8I3X4_PLAF7	Plasmodium falciparum	2	0.7024
Purine nucleoside phosphorylase	Q8I3X4	Q8I3X4_PLAF7	Plasmodium falciparum	2	0.7024
Carbonic anhydrase 4	Q64444	CAH4_MOUSE	Mus musculus	2	0.7023
Carbonic anhydrase 4	Q64444	CAH4_MOUSE	Mus musculus	2	0.7023
Genome polyprotein	O92972	POLG_HCVJ4	Hepatitis C virus genotype 1b	2	0.7019
Genome polyprotein	O92972	POLG_HCVJ4	Hepatitis C virus genotype 1b	2	0.7019
Phosphotriesterase	Q5KZU5	Q5KZU5_GEOKA	Geobacillus kaustophilus	2	0.7015
Phosphotriesterase	Q5KZU5	Q5KZU5_GEOKA	Geobacillus kaustophilus	2	0.7015
Stromelysin-1	P08254	MMP3_HUMAN	Homo sapiens	2	0.7014
Stromelysin-1	P08254	MMP3_HUMAN	Homo sapiens	2	0.7014
Albumin	P02768	ALBU_HUMAN	Homo sapiens	2	0.7009
Albumin	P02768	ALBU_HUMAN	Homo sapiens	2	0.7009
Tetracycline repressor protein class D	P0ACT4	TETR4_ECOLX	Escherichia coli	2	0.7003
Tetracycline repressor protein class D	P0ACT4	TETR4_ECOLX	Escherichia coli	2	0.7003
Peptidyl-prolyl cis-trans isomerase FKBP1A	P62942	FKB1A_HUMAN	Homo sapiens	3	0.7002
Peptidyl-prolyl cis-trans isomerase FKBP1A	P62942	FKB1A_HUMAN	Homo sapiens	3	0.7002

Download SDF