Daphnelone - Compound Card

Daphnelone

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Daphnelone

Structure
Zoomed Structure
  • Family: Thymelaeaceae
  • Kingdom: Plantae
  • Class: Phenolic
Canonical Smiles OC(CC(=O)c1ccc(cc1)O)CCc1ccccc1
InChI InChI=1S/C17H18O3/c18-15-10-7-14(8-11-15)17(20)12-16(19)9-6-13-4-2-1-3-5-13/h1-5,7-8,10-11,16,18-19H,6,9,12H2
InChIKey NNPDNNXUSPXBRO-UHFFFAOYSA-N
Formula C17H18O3
HBA 3
HBD 2
MW 270.33
Rotatable Bonds 6
TPSA 57.53
LogP 2.96
Number Rings 2
Number Aromatic Rings 2
Heavy Atom Count 20
Formal Charge 0
Fraction CSP3 0.24
Exact Mass 270.13
Number of Lipinski Rule Violations 0
# Species Family Kingdom NCBI Taxonomy ID
1 Thymelaea lythroides Thymelaeaceae Plantae 224054

Showing of synonyms

  • Kabbaj FZ, Lai D, et al. (2013). Chemical constituents from aerial parts of Thymelaea lythroides. Biochemical Systematics and Ecology,2013,51,153-155. [View]
Pubchem: 5316300
Nmrshiftdb2: 60145367

No compound-protein relationship available.

Structure

SMILES: c1ccccc1C(=O)CCCCc2ccccc2

Level: 1

Mol. Weight: 238.33 g/mol

Structure

SMILES: c1ccccc1

Level: 0

Mol. Weight: 78.11 g/mol

No bioactivities available.

Absorption

Caco-2 (logPapp)
-4.78
Human Oral Bioavailability 20%
Bioavailable
Human Intestinal Absorption
Absorbed
Madin-Darby Canine Kidney
-4.310
Human Oral Bioavailability 50%
Bioavailable
P-Glycoprotein Inhibitor
Non-Inhibitor
P-Glycoprotein Substrate
Non-Substrate
Skin Permeability
-2.94

Distribution

Blood-Brain Barrier (CNS)
-
Blood-Brain Barrier
Non-Penetrable
Fraction Unbound (Human)
0.940
Plasma Protein Binding
51.84
Steady State Volume of Distribution
-

Metabolism

Breast Cancer Resistance Protein
Non-Inhibitor
CYP 1A2 Inhibitor
Non-Inhibitor
CYP 1A2 Substrate
Substrate
CYP 2C19 Inhibitor
Inhibitor
CYP 2C19 Substrate
Substrate
CYP 2C9 Inhibitor
Inhibitor
CYP 2C9 Substrate
Substrate
CYP 2D6 Inhibitor
Non-Inhibitor
CYP 2D6 Substrate
Non-Substrate
CYP 3A4 Inhibitor
Non-Inhibitor
CYP 3A4 Substrate
Substrate
OATP1B1
Non-Inhibitor
OATP1B3
Non-Inhibitor

Excretion

Clearance
6.450
Organic Cation Transporter 2
Non-Inhibitor
Half-Life of Drug
-

Toxicity

AMES Mutagenesis
Safe
Avian
Safe
Bee
Safe
Bioconcentration Factor
0.490
Biodegradation
Safe
Carcinogenesis
Safe
Crustacean
Safe
Liver Injury I (DILI)
Safe
Eye Corrosion
Safe
Eye Irritation
Safe
Maximum Tolerated Dose
0.390
Liver Injury II
Toxic
hERG Blockers
Safe
Daphnia Maga
4.930
Micronucleos
Toxic
NR-AhR
Safe
NR-AR
Safe
NR-AR-LBD
Safe
NR-Aromatase
Safe
NR-ER
Toxic
NR-ER-LBD
Safe
NR-GR
Safe
NR-PPAR-gamma
Safe
NR-TR
Safe
T. Pyriformis
3.860
Rat (Acute)
1.910
Rat (Chronic Oral)
2.210
Fathead Minnow
4.170
Respiratory Disease
Safe
Skin Sensitisation
Toxic
SR-ARE
Safe
SR-ATAD5
Safe
SR-HSE
Safe
SR-MMP
Toxic
SR-p53
Safe

General Properties

Boiling Point
374.860
Hydration Free Energy
-9.340
Log(D) at pH=7.4
2.400
Log(P)
3.05
Log S
-3.42
Log(Vapor Pressure)
-7.06
Melting Point
111.37
pKa Acid
8.43
pKa Basic
5.62
Protein Name UniProt ID Entry Name Species #Pharmacophore Points Probability (0.7 ≤ Tversky Score ≤ 1.0)
Glycogen synthase Q9V2J8 Q9V2J8_PYRAB Pyrococcus abyssi 3 0.9880
Glycogen synthase Q9V2J8 Q9V2J8_PYRAB Pyrococcus abyssi 3 0.9880
Mycocyclosin synthase P9WPP7 CP121_MYCTU Mycobacterium tuberculosis 3 0.9813
Mycocyclosin synthase P9WPP7 CP121_MYCTU Mycobacterium tuberculosis 3 0.9813
Endothiapepsin P11838 CARP_CRYPA Cryphonectria parasitica 3 0.9752
Endothiapepsin P11838 CARP_CRYPA Cryphonectria parasitica 3 0.9752
Urokinase-type plasminogen activator P00749 UROK_HUMAN Homo sapiens 3 0.9691
Urokinase-type plasminogen activator P00749 UROK_HUMAN Homo sapiens 3 0.9691
cGMP-specific 3',5'-cyclic phosphodiesterase O76074 PDE5A_HUMAN Homo sapiens 3 0.9652
cGMP-specific 3',5'-cyclic phosphodiesterase O76074 PDE5A_HUMAN Homo sapiens 3 0.9652
Carnitine O-palmitoyltransferase 2, mitochondrial P18886 CPT2_RAT Rattus norvegicus 3 0.9648
Carnitine O-palmitoyltransferase 2, mitochondrial P18886 CPT2_RAT Rattus norvegicus 3 0.9648
Glycogen synthase Q9V2J8 Q9V2J8_PYRAB Pyrococcus abyssi 3 0.9644
Glycogen synthase Q9V2J8 Q9V2J8_PYRAB Pyrococcus abyssi 3 0.9644
Flavoredoxin Q72HI0 Q72HI0_THET2 Thermus thermophilus 3 0.9605
Flavoredoxin Q72HI0 Q72HI0_THET2 Thermus thermophilus 3 0.9605
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A Q9Y233 PDE10_HUMAN Homo sapiens 3 0.9600
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A Q9Y233 PDE10_HUMAN Homo sapiens 3 0.9600
Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase Q9TQS6 DHDH_MACFA Macaca fascicularis 3 0.9569
Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase Q9TQS6 DHDH_MACFA Macaca fascicularis 3 0.9569
Alpha-ketoglutarate-dependent dioxygenase FTO Q9C0B1 FTO_HUMAN Homo sapiens 3 0.9567
Alpha-ketoglutarate-dependent dioxygenase FTO Q9C0B1 FTO_HUMAN Homo sapiens 3 0.9567
Chloramphenicol 3-O phosphotransferase Q56148 CPT_STRVP Streptomyces venezuelae 3 0.9564
Chloramphenicol 3-O phosphotransferase Q56148 CPT_STRVP Streptomyces venezuelae 3 0.9564
Macrophage metalloelastase P39900 MMP12_HUMAN Homo sapiens 3 0.9558
Macrophage metalloelastase P39900 MMP12_HUMAN Homo sapiens 3 0.9558
Mitogen-activated protein kinase 14 Q16539 MK14_HUMAN Homo sapiens 3 0.9553
Mitogen-activated protein kinase 14 Q16539 MK14_HUMAN Homo sapiens 3 0.9553
Lactotransferrin P24627 TRFL_BOVIN Bos taurus 3 0.9544
Glycogen synthase kinase-3 beta P49841 GSK3B_HUMAN Homo sapiens 3 0.9544
Lactotransferrin P24627 TRFL_BOVIN Bos taurus 3 0.9544
Glycogen synthase kinase-3 beta P49841 GSK3B_HUMAN Homo sapiens 3 0.9544
Heat shock protein HSP 90-alpha P07900 HS90A_HUMAN Homo sapiens 3 0.9540
Heat shock protein HSP 90-alpha P07900 HS90A_HUMAN Homo sapiens 3 0.9540
3',5'-cyclic-AMP phosphodiesterase 4D Q08499 PDE4D_HUMAN Homo sapiens 3 0.9535
3',5'-cyclic-AMP phosphodiesterase 4D Q08499 PDE4D_HUMAN Homo sapiens 3 0.9535
Beta-secretase 1 P56817 BACE1_HUMAN Homo sapiens 3 0.9521
Beta-secretase 1 P56817 BACE1_HUMAN Homo sapiens 3 0.9521
Neocarzinostatin P0A3R9 NCZS_STRCZ Streptomyces carzinostaticus 3 0.9498
Neocarzinostatin P0A3R9 NCZS_STRCZ Streptomyces carzinostaticus 3 0.9498
Bromodomain-containing protein 2 P25440 BRD2_HUMAN Homo sapiens 3 0.9493
Bromodomain-containing protein 2 P25440 BRD2_HUMAN Homo sapiens 3 0.9493
Coagulation factor X P00742 FA10_HUMAN Homo sapiens 3 0.9491
Coagulation factor X P00742 FA10_HUMAN Homo sapiens 3 0.9491
Flavonoid 3-O-glucosyltransferase A6XNC6 UGFGT_MEDTR Medicago truncatula 3 0.9454
Flavonoid 3-O-glucosyltransferase A6XNC6 UGFGT_MEDTR Medicago truncatula 3 0.9454
Chloramphenicol 3-O phosphotransferase Q56148 CPT_STRVP Streptomyces venezuelae 3 0.9439
Chloramphenicol 3-O phosphotransferase Q56148 CPT_STRVP Streptomyces venezuelae 3 0.9439
3',5'-cyclic-AMP phosphodiesterase 4D Q08499 PDE4D_HUMAN Homo sapiens 3 0.9431
3',5'-cyclic-AMP phosphodiesterase 4D Q08499 PDE4D_HUMAN Homo sapiens 3 0.9431
Heat shock protein HSP 90-alpha P07900 HS90A_HUMAN Homo sapiens 3 0.9421
Heat shock protein HSP 90-alpha P07900 HS90A_HUMAN Homo sapiens 3 0.9421
Streptogramin A acetyltransferase P50870 VATD_ENTFC Enterococcus faecium 3 0.9416
Streptogramin A acetyltransferase P50870 VATD_ENTFC Enterococcus faecium 3 0.9416
Norsolorinic acid synthase Q12053 AFLC_ASPPU Aspergillus parasiticus 3 0.9396
Norsolorinic acid synthase Q12053 AFLC_ASPPU Aspergillus parasiticus 3 0.9396
D-aminoacyl-tRNA deacylase Q8IIS0 DTD_PLAF7 Plasmodium falciparum 3 0.9395
D-aminoacyl-tRNA deacylase Q8IIS0 DTD_PLAF7 Plasmodium falciparum 3 0.9395
Beta-secretase 1 P56817 BACE1_HUMAN Homo sapiens 3 0.9384
Beta-secretase 1 P56817 BACE1_HUMAN Homo sapiens 3 0.9384
Glutathione S-transferase F2 P46422 GSTF2_ARATH Arabidopsis thaliana 3 0.9381
Glutathione S-transferase F2 P46422 GSTF2_ARATH Arabidopsis thaliana 3 0.9381
Heat shock protein HSP 90-alpha P07900 HS90A_HUMAN Homo sapiens 3 0.9370
Heat shock protein HSP 90-alpha P07900 HS90A_HUMAN Homo sapiens 3 0.9370
Flavin-dependent monooxygenase Q93L51 TETX_BACT4 Bacteroides thetaiotaomicron 3 0.9350
Flavin-dependent monooxygenase Q93L51 TETX_BACT4 Bacteroides thetaiotaomicron 3 0.9350
Soluble acetylcholine receptor Q8WSF8 Q8WSF8_APLCA Aplysia californica 3 0.9342
Soluble acetylcholine receptor Q8WSF8 Q8WSF8_APLCA Aplysia californica 3 0.9342
Serine/threonine-protein kinase Chk2 O96017 CHK2_HUMAN Homo sapiens 3 0.9322
Serine/threonine-protein kinase Chk2 O96017 CHK2_HUMAN Homo sapiens 3 0.9322
Chitinase A Q9AMP1 Q9AMP1_VIBHA Vibrio harveyi 3 0.9311
Chitinase A Q9AMP1 Q9AMP1_VIBHA Vibrio harveyi 3 0.9311
cGMP-dependent 3',5'-cyclic phosphodiesterase O00408 PDE2A_HUMAN Homo sapiens 3 0.9304
cGMP-dependent 3',5'-cyclic phosphodiesterase O00408 PDE2A_HUMAN Homo sapiens 3 0.9304
Beta-secretase 1 P56817 BACE1_HUMAN Homo sapiens 3 0.9280
Beta-secretase 1 P56817 BACE1_HUMAN Homo sapiens 3 0.9280
Glycogen synthase kinase-3 beta P49841 GSK3B_HUMAN Homo sapiens 3 0.9279
Glycogen synthase kinase-3 beta P49841 GSK3B_HUMAN Homo sapiens 3 0.9279
High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A O76083 PDE9A_HUMAN Homo sapiens 3 0.9240
High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A O76083 PDE9A_HUMAN Homo sapiens 3 0.9240
Ephrin type-B receptor 4 P54760 EPHB4_HUMAN Homo sapiens 3 0.9236
Ephrin type-B receptor 4 P54760 EPHB4_HUMAN Homo sapiens 3 0.9236
Biflaviolin synthase CYP158A1 Q9KZF5 C1581_STRCO Streptomyces coelicolor / M145) 3 0.9229
Biflaviolin synthase CYP158A1 Q9KZF5 C1581_STRCO Streptomyces coelicolor / M145) 3 0.9229
Glycogen phosphorylase, muscle form P00489 PYGM_RABIT Oryctolagus cuniculus 3 0.9226
Urokinase-type plasminogen activator P00749 UROK_HUMAN Homo sapiens 3 0.9226
Glycogen phosphorylase, muscle form P00489 PYGM_RABIT Oryctolagus cuniculus 3 0.9226
Urokinase-type plasminogen activator P00749 UROK_HUMAN Homo sapiens 3 0.9226
Catalase-peroxidase Q3JNW6 KATG_BURP1 Burkholderia pseudomallei 3 0.9195
Catalase-peroxidase Q3JNW6 KATG_BURP1 Burkholderia pseudomallei 3 0.9195
Beta-1 adrenergic receptor P07700 ADRB1_MELGA Meleagris gallopavo 4 0.9191
Coagulation factor X P00742 FA10_HUMAN Homo sapiens 3 0.9191
Coagulation factor X P00742 FA10_HUMAN Homo sapiens 3 0.9191
Beta-1 adrenergic receptor P07700 ADRB1_MELGA Meleagris gallopavo 4 0.9191
Serine/threonine-protein kinase 24 Q9Y6E0 STK24_HUMAN Homo sapiens 3 0.9189
Serine/threonine-protein kinase 24 Q9Y6E0 STK24_HUMAN Homo sapiens 3 0.9189
Activin receptor type-1 Q04771 ACVR1_HUMAN Homo sapiens 3 0.9182
Activin receptor type-1 Q04771 ACVR1_HUMAN Homo sapiens 3 0.9182
Genome polyprotein P26663 POLG_HCVBK Hepatitis C virus genotype 1b 3 0.9181
Genome polyprotein P26663 POLG_HCVBK Hepatitis C virus genotype 1b 3 0.9181
NADPH-dependent oxidoreductase 2-alkenal reductase Q39172 AER_ARATH Arabidopsis thaliana 3 0.9166
NADPH-dependent oxidoreductase 2-alkenal reductase Q39172 AER_ARATH Arabidopsis thaliana 3 0.9166
Pantothenate synthetase P9WIL5 PANC_MYCTU Mycobacterium tuberculosis 3 0.9161
Pantothenate synthetase P9WIL5 PANC_MYCTU Mycobacterium tuberculosis 3 0.9161
ALK tyrosine kinase receptor Q9UM73 ALK_HUMAN Homo sapiens 3 0.9149
ALK tyrosine kinase receptor Q9UM73 ALK_HUMAN Homo sapiens 3 0.9149
Heat shock protein HSP 90-alpha P07900 HS90A_HUMAN Homo sapiens 3 0.9147
Heat shock protein HSP 90-alpha P07900 HS90A_HUMAN Homo sapiens 3 0.9147
Chloramphenicol acetyltransferase P62577 CAT_ECOLX Escherichia coli 3 0.9142
Chloramphenicol acetyltransferase P62577 CAT_ECOLX Escherichia coli 3 0.9142
Queuine tRNA-ribosyltransferase P28720 TGT_ZYMMO Zymomonas mobilis subsp. mobilis 3 0.9137
Queuine tRNA-ribosyltransferase P28720 TGT_ZYMMO Zymomonas mobilis subsp. mobilis 3 0.9137
Heat shock protein HSP 90-alpha P07900 HS90A_HUMAN Homo sapiens 3 0.9132
Heat shock protein HSP 90-alpha P07900 HS90A_HUMAN Homo sapiens 3 0.9132
TGF-beta-activated kinase 1 and MAP3K7-binding protein 1 Q15750 TAB1_HUMAN Homo sapiens 3 0.9126
TGF-beta-activated kinase 1 and MAP3K7-binding protein 1 Q15750 TAB1_HUMAN Homo sapiens 3 0.9126
Acetolactate synthase, chloroplastic P17597 ILVB_ARATH Arabidopsis thaliana 3 0.9104
Acetolactate synthase, chloroplastic P17597 ILVB_ARATH Arabidopsis thaliana 3 0.9104
Tetracycline repressor protein class D P0ACT4 TETR4_ECOLX Escherichia coli 3 0.9079
Tetracycline repressor protein class D P0ACT4 TETR4_ECOLX Escherichia coli 3 0.9079
Prothrombin P00734 THRB_HUMAN Homo sapiens 3 0.9076
Queuine tRNA-ribosyltransferase P28720 TGT_ZYMMO Zymomonas mobilis subsp. mobilis 3 0.9076
Prothrombin P00734 THRB_HUMAN Homo sapiens 3 0.9076
Queuine tRNA-ribosyltransferase P28720 TGT_ZYMMO Zymomonas mobilis subsp. mobilis 3 0.9076
Heat shock protein HSP 90-alpha P07900 HS90A_HUMAN Homo sapiens 3 0.9060
Heat shock protein HSP 90-alpha P07900 HS90A_HUMAN Homo sapiens 3 0.9060
Ribosyldihydronicotinamide dehydrogenase [quinone] P16083 NQO2_HUMAN Homo sapiens 3 0.9047
Ribosyldihydronicotinamide dehydrogenase [quinone] P16083 NQO2_HUMAN Homo sapiens 3 0.9047
Glycogen synthase kinase-3 beta P49841 GSK3B_HUMAN Homo sapiens 3 0.9028
Glycogen synthase kinase-3 beta P49841 GSK3B_HUMAN Homo sapiens 3 0.9028
Mitogen-activated protein kinase kinase kinase 5 Q99683 M3K5_HUMAN Homo sapiens 3 0.9000
Mitogen-activated protein kinase kinase kinase 5 Q99683 M3K5_HUMAN Homo sapiens 3 0.9000
Cyclin-dependent kinase 2 P24941 CDK2_HUMAN Homo sapiens 3 0.8987
Cyclin-dependent kinase 2 P24941 CDK2_HUMAN Homo sapiens 3 0.8987
Diphtheria toxin P00588 DTX_CORBE Corynephage beta 3 0.8979
Diphtheria toxin P00588 DTX_CORBE Corynephage beta 3 0.8979
Beta-secretase 1 P56817 BACE1_HUMAN Homo sapiens 3 0.8973
Beta-secretase 1 P56817 BACE1_HUMAN Homo sapiens 3 0.8973
Decaprenylphosphoryl-beta-D-ribose oxidase I6X8C4 I6X8C4_MYCTU Mycobacterium tuberculosis 3 0.8966
Decaprenylphosphoryl-beta-D-ribose oxidase I6X8C4 I6X8C4_MYCTU Mycobacterium tuberculosis 3 0.8966
Serine/threonine-protein kinase pim-1 P11309 PIM1_HUMAN Homo sapiens 3 0.8958
Serine/threonine-protein kinase pim-1 P11309 PIM1_HUMAN Homo sapiens 3 0.8958
Stromelysin-1 P08254 MMP3_HUMAN Homo sapiens 3 0.8957
Stromelysin-1 P08254 MMP3_HUMAN Homo sapiens 3 0.8957
DNA gyrase subunit A P0AES5 GYRA_SHIFL Shigella flexneri 3 0.8945
DNA gyrase subunit A P0AES5 GYRA_SHIFL Shigella flexneri 3 0.8945
Coagulation factor X P00742 FA10_HUMAN Homo sapiens 3 0.8944
Coagulation factor X P00742 FA10_HUMAN Homo sapiens 3 0.8944
5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase P0AF12 MTNN_ECOLI Escherichia coli 3 0.8942
5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase P0AF12 MTNN_ECOLI Escherichia coli 3 0.8942
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A Q9Y233 PDE10_HUMAN Homo sapiens 3 0.8938
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A Q9Y233 PDE10_HUMAN Homo sapiens 3 0.8938
Prothrombin P00734 THRB_HUMAN Homo sapiens 3 0.8925
Prothrombin P00734 THRB_HUMAN Homo sapiens 3 0.8925
Gag-Pol polyprotein P03369 POL_HV1A2 Human immunodeficiency virus type 1 group M subtype B 3 0.8888
Gag-Pol polyprotein P03369 POL_HV1A2 Human immunodeficiency virus type 1 group M subtype B 3 0.8888
Poly [ADP-ribose] polymerase 1 P09874 PARP1_HUMAN Homo sapiens 3 0.8874
Poly [ADP-ribose] polymerase 1 P09874 PARP1_HUMAN Homo sapiens 3 0.8874
Coniferyl alcohol 9-O-methyltransferase A6XNE6 A6XNE6_9ROSI Linum nodiflorum 3 0.8868
Serine/threonine-protein kinase 10 O94804 STK10_HUMAN Homo sapiens 3 0.8868
Serine/threonine-protein kinase 10 O94804 STK10_HUMAN Homo sapiens 3 0.8868
Coniferyl alcohol 9-O-methyltransferase A6XNE6 A6XNE6_9ROSI Linum nodiflorum 3 0.8868
11-beta-hydroxysteroid dehydrogenase 1 P28845 DHI1_HUMAN Homo sapiens 3 0.8864
11-beta-hydroxysteroid dehydrogenase 1 P28845 DHI1_HUMAN Homo sapiens 3 0.8864
Mycocyclosin synthase P9WPP7 CP121_MYCTU Mycobacterium tuberculosis 3 0.8845
Mycocyclosin synthase P9WPP7 CP121_MYCTU Mycobacterium tuberculosis 3 0.8845
Biflaviolin synthase CYP158A2 Q9FCA6 C1582_STRCO Streptomyces coelicolor / M145) 3 0.8840
Biflaviolin synthase CYP158A2 Q9FCA6 C1582_STRCO Streptomyces coelicolor / M145) 3 0.8840
Protein S100-A13 Q99584 S10AD_HUMAN Homo sapiens 3 0.8839
Protein S100-A13 Q99584 S10AD_HUMAN Homo sapiens 3 0.8839
Biflaviolin synthase CYP158A2 Q9FCA6 C1582_STRCO Streptomyces coelicolor / M145) 3 0.8833
Biflaviolin synthase CYP158A2 Q9FCA6 C1582_STRCO Streptomyces coelicolor / M145) 3 0.8833
Dihydroorotate dehydrogenase (quinone), mitochondrial Q08210 PYRD_PLAF7 Plasmodium falciparum 3 0.8827
Dihydroorotate dehydrogenase (quinone), mitochondrial Q08210 PYRD_PLAF7 Plasmodium falciparum 3 0.8827
17beta-hydroxysteroid dehydrogenase O93874 O93874_COCLU Cochliobolus lunatus 3 0.8822
17beta-hydroxysteroid dehydrogenase O93874 O93874_COCLU Cochliobolus lunatus 3 0.8822
ATP-dependent molecular chaperone HSP82 P02829 HSP82_YEAST Saccharomyces cerevisiae 3 0.8805
ATP-dependent molecular chaperone HSP82 P02829 HSP82_YEAST Saccharomyces cerevisiae 3 0.8805
Nicotinamide phosphoribosyltransferase P43490 NAMPT_HUMAN Homo sapiens 3 0.8782
Nicotinamide phosphoribosyltransferase P43490 NAMPT_HUMAN Homo sapiens 3 0.8782
3'-5' exoribonuclease Rv2179c P9WJ73 EXRBN_MYCTU Mycobacterium tuberculosis 3 0.8779
3'-5' exoribonuclease Rv2179c P9WJ73 EXRBN_MYCTU Mycobacterium tuberculosis 3 0.8779
Histone deacetylase 8 Q9BY41 HDAC8_HUMAN Homo sapiens 3 0.8765
Histone deacetylase 8 Q9BY41 HDAC8_HUMAN Homo sapiens 3 0.8765
Mitogen-activated protein kinase 14 Q16539 MK14_HUMAN Homo sapiens 3 0.8764
Mitogen-activated protein kinase 14 Q16539 MK14_HUMAN Homo sapiens 3 0.8764
Endothiapepsin P11838 CARP_CRYPA Cryphonectria parasitica 3 0.8763
Endothiapepsin P11838 CARP_CRYPA Cryphonectria parasitica 3 0.8763
Serine/threonine-protein kinase 24 Q9Y6E0 STK24_HUMAN Homo sapiens 3 0.8760
Serine/threonine-protein kinase 24 Q9Y6E0 STK24_HUMAN Homo sapiens 3 0.8760
High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A O76083 PDE9A_HUMAN Homo sapiens 3 0.8739
High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A O76083 PDE9A_HUMAN Homo sapiens 3 0.8739
Heat shock protein HSP 90-beta P08238 HS90B_HUMAN Homo sapiens 3 0.8738
Heat shock protein HSP 90-beta P08238 HS90B_HUMAN Homo sapiens 3 0.8738
Nitric oxide synthase, inducible P29477 NOS2_MOUSE Mus musculus 3 0.8715
Nitric oxide synthase, inducible P29477 NOS2_MOUSE Mus musculus 3 0.8715
Epidermal growth factor receptor P00533 EGFR_HUMAN Homo sapiens 3 0.8705
Epidermal growth factor receptor P00533 EGFR_HUMAN Homo sapiens 3 0.8705
Mitogen-activated protein kinase 14 Q16539 MK14_HUMAN Homo sapiens 3 0.8701
Mitogen-activated protein kinase 14 Q16539 MK14_HUMAN Homo sapiens 3 0.8701
cAMP-dependent protein kinase catalytic subunit alpha P05132 KAPCA_MOUSE Mus musculus 3 0.8689
cAMP-dependent protein kinase catalytic subunit alpha P05132 KAPCA_MOUSE Mus musculus 3 0.8689
cAMP-dependent protein kinase catalytic subunit alpha P00517 KAPCA_BOVIN Bos taurus 3 0.8682
cAMP-dependent protein kinase catalytic subunit alpha P00517 KAPCA_BOVIN Bos taurus 3 0.8682
Karilysin D0EM77 KLY_TANFA Tannerella forsythia 3 0.8671
Karilysin D0EM77 KLY_TANFA Tannerella forsythia 3 0.8671
Fibroblast growth factor receptor 2 P21802 FGFR2_HUMAN Homo sapiens 3 0.8659
Fibroblast growth factor receptor 2 P21802 FGFR2_HUMAN Homo sapiens 3 0.8659
Major pollen allergen Bet v 1-A P15494 BEV1A_BETPN Betula pendula 3 0.8656
Major pollen allergen Bet v 1-A P15494 BEV1A_BETPN Betula pendula 3 0.8656
Rhodopsin kinase GRK1 P28327 GRK1_BOVIN Bos taurus 3 0.8634
Rhodopsin kinase GRK1 P28327 GRK1_BOVIN Bos taurus 3 0.8634
Lactoperoxidase P80025 PERL_BOVIN Bos taurus 3 0.8624
Lactoperoxidase P80025 PERL_BOVIN Bos taurus 3 0.8624
Cytochrome P450 1A1 P04798 CP1A1_HUMAN Homo sapiens 3 0.8616
Cytochrome P450 1A1 P04798 CP1A1_HUMAN Homo sapiens 3 0.8616
Basic phospholipase A2 VRV-PL-VIIIa P59071 PA2B8_DABRR Daboia russelii 3 0.8613
Basic phospholipase A2 VRV-PL-VIIIa P59071 PA2B8_DABRR Daboia russelii 3 0.8613
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform P48736 PK3CG_HUMAN Homo sapiens 3 0.8610
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform P48736 PK3CG_HUMAN Homo sapiens 3 0.8610
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform P48736 PK3CG_HUMAN Homo sapiens 3 0.8606
Serine/threonine-protein kinase Chk1 O14757 CHK1_HUMAN Homo sapiens 3 0.8606
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform P48736 PK3CG_HUMAN Homo sapiens 3 0.8606
Serine/threonine-protein kinase Chk1 O14757 CHK1_HUMAN Homo sapiens 3 0.8606
Peptidyl-prolyl cis-trans isomerase FKBP1A P62942 FKB1A_HUMAN Homo sapiens 3 0.8555
Peptidyl-prolyl cis-trans isomerase FKBP1A P62942 FKB1A_HUMAN Homo sapiens 3 0.8555
Carbonyl reductase [NADPH] 1 P16152 CBR1_HUMAN Homo sapiens 3 0.8538
Carbonyl reductase [NADPH] 1 P16152 CBR1_HUMAN Homo sapiens 3 0.8538
Epidermal growth factor receptor P00533 EGFR_HUMAN Homo sapiens 3 0.8524
Epidermal growth factor receptor P00533 EGFR_HUMAN Homo sapiens 3 0.8524
Mitogen-activated protein kinase 14 Q16539 MK14_HUMAN Homo sapiens 3 0.8515
Mitogen-activated protein kinase 14 Q16539 MK14_HUMAN Homo sapiens 3 0.8515
Repressor protein Q7X0D9 Q7X0D9_ACIAD Acinetobacter baylyi 3 0.8495
Repressor protein Q7X0D9 Q7X0D9_ACIAD Acinetobacter baylyi 3 0.8495
Serine/threonine-protein kinase pim-1 P11309 PIM1_HUMAN Homo sapiens 3 0.8485
Serine/threonine-protein kinase pim-1 P11309 PIM1_HUMAN Homo sapiens 3 0.8485
Coagulation factor X P00742 FA10_HUMAN Homo sapiens 3 0.8484
Coagulation factor X P00742 FA10_HUMAN Homo sapiens 3 0.8484
2-phospho-L-lactate transferase Q8PVT6 COFD_METMA Methanosarcina mazei 3 0.8482
2-phospho-L-lactate transferase Q8PVT6 COFD_METMA Methanosarcina mazei 3 0.8482
3',5'-cyclic-AMP phosphodiesterase 4D Q08499 PDE4D_HUMAN Homo sapiens 3 0.8473
3',5'-cyclic-AMP phosphodiesterase 4D Q08499 PDE4D_HUMAN Homo sapiens 3 0.8473
Heat shock protein HSP 90-alpha P07900 HS90A_HUMAN Homo sapiens 3 0.8473
Heat shock protein HSP 90-alpha P07900 HS90A_HUMAN Homo sapiens 3 0.8473
Purine nucleoside phosphorylase P00491 PNPH_HUMAN Homo sapiens 3 0.8467
Purine nucleoside phosphorylase P00491 PNPH_HUMAN Homo sapiens 3 0.8467
Mitogen-activated protein kinase 14 Q16539 MK14_HUMAN Homo sapiens 3 0.8463
Mitogen-activated protein kinase 14 Q16539 MK14_HUMAN Homo sapiens 3 0.8463
Nicotinamide phosphoribosyltransferase P43490 NAMPT_HUMAN Homo sapiens 3 0.8437
Nicotinamide phosphoribosyltransferase P43490 NAMPT_HUMAN Homo sapiens 3 0.8437
Activin receptor type-1 Q04771 ACVR1_HUMAN Homo sapiens 3 0.8420
Activin receptor type-1 Q04771 ACVR1_HUMAN Homo sapiens 3 0.8420
cytokinin dehydrogenase E3T1W8 E3T1W8_MAIZE Zea mays 3 0.8407
cytokinin dehydrogenase E3T1W8 E3T1W8_MAIZE Zea mays 3 0.8407
Mycinamicin III 3''-O-methyltransferase Q49492 MYCF_MICGR Micromonospora griseorubida 2 0.8404
Mycinamicin III 3''-O-methyltransferase Q49492 MYCF_MICGR Micromonospora griseorubida 2 0.8404
Cytochrome P450 2D6 P10635 CP2D6_HUMAN Homo sapiens 3 0.8401
Cytochrome P450 2D6 P10635 CP2D6_HUMAN Homo sapiens 3 0.8401
Histone deacetylase 4 P56524 HDAC4_HUMAN Homo sapiens 3 0.8372
Histone deacetylase 4 P56524 HDAC4_HUMAN Homo sapiens 3 0.8372
Prothrombin P00734 THRB_HUMAN Homo sapiens 3 0.8358
Prothrombin P00734 THRB_HUMAN Homo sapiens 3 0.8358
Na(+):neurotransmitter symporter (Snf family) O67854 O67854_AQUAE Aquifex aeolicus 3 0.8357
Na(+):neurotransmitter symporter (Snf family) O67854 O67854_AQUAE Aquifex aeolicus 3 0.8357
7,8-dihydroneopterin aldolase J7VEZ6 J7VEZ6_BACCE Bacillus cereus BAG3X2-1 3 0.8351
7,8-dihydroneopterin aldolase J7VEZ6 J7VEZ6_BACCE Bacillus cereus BAG3X2-1 3 0.8351
DNA topoisomerase 4 subunit B H7C794 PARE_ENTFA Enterococcus faecalis 3 0.8340
DNA topoisomerase 4 subunit B H7C794 PARE_ENTFA Enterococcus faecalis 3 0.8340
Mitogen-activated protein kinase 14 Q16539 MK14_HUMAN Homo sapiens 3 0.8323
Mitogen-activated protein kinase 14 Q16539 MK14_HUMAN Homo sapiens 3 0.8323
Nitric oxide synthase, inducible P29477 NOS2_MOUSE Mus musculus 3 0.8317
Nitric oxide synthase, inducible P29477 NOS2_MOUSE Mus musculus 3 0.8317
Protoporphyrinogen oxidase P50336 PPOX_HUMAN Homo sapiens 3 0.8306
Protoporphyrinogen oxidase P50336 PPOX_HUMAN Homo sapiens 3 0.8306
Valacyclovir hydrolase Q86WA6 BPHL_HUMAN Homo sapiens 3 0.8300
Valacyclovir hydrolase Q86WA6 BPHL_HUMAN Homo sapiens 3 0.8300
Heat shock protein HSP 90-alpha P07900 HS90A_HUMAN Homo sapiens 3 0.8299
Heat shock protein HSP 90-alpha P07900 HS90A_HUMAN Homo sapiens 3 0.8299
Heat shock protein HSP 90-alpha P07900 HS90A_HUMAN Homo sapiens 3 0.8298
Heat shock protein HSP 90-alpha P07900 HS90A_HUMAN Homo sapiens 3 0.8298
Abscisic acid receptor PYR1 O49686 PYR1_ARATH Arabidopsis thaliana 3 0.8286
Abscisic acid receptor PYR1 O49686 PYR1_ARATH Arabidopsis thaliana 3 0.8286
MAP kinase-activated protein kinase 2 P49137 MAPK2_HUMAN Homo sapiens 3 0.8285
MAP kinase-activated protein kinase 2 P49137 MAPK2_HUMAN Homo sapiens 3 0.8285
Cytochrome P450 S6BVH1 S6BVH1_RHOER Rhodococcus erythropolis 3 0.8282
Cytochrome P450 S6BVH1 S6BVH1_RHOER Rhodococcus erythropolis 3 0.8282
Endothiapepsin P11838 CARP_CRYPA Cryphonectria parasitica 3 0.8275
Endothiapepsin P11838 CARP_CRYPA Cryphonectria parasitica 3 0.8275
Poly [ADP-ribose] polymerase tankyrase-2 Q9H2K2 TNKS2_HUMAN Homo sapiens 3 0.8274
Poly [ADP-ribose] polymerase tankyrase-2 Q9H2K2 TNKS2_HUMAN Homo sapiens 3 0.8274
Mycocyclosin synthase P9WPP7 CP121_MYCTU Mycobacterium tuberculosis 3 0.8272
Mycocyclosin synthase P9WPP7 CP121_MYCTU Mycobacterium tuberculosis 3 0.8272
Poly [ADP-ribose] polymerase 1 P09874 PARP1_HUMAN Homo sapiens 3 0.8271
Poly [ADP-ribose] polymerase 1 P09874 PARP1_HUMAN Homo sapiens 3 0.8271
17beta-hydroxysteroid dehydrogenase O93874 O93874_COCLU Cochliobolus lunatus 3 0.8263
17beta-hydroxysteroid dehydrogenase O93874 O93874_COCLU Cochliobolus lunatus 3 0.8263
Nitric oxide synthase, inducible P29477 NOS2_MOUSE Mus musculus 3 0.8259
Nitric oxide synthase, inducible P29477 NOS2_MOUSE Mus musculus 3 0.8259
Pteridine reductase 1 Q01782 PTR1_LEIMA Leishmania major 3 0.8253
Pteridine reductase 1 Q01782 PTR1_LEIMA Leishmania major 3 0.8253
Capsid protein Q9WBP8 Q9WBP8_9VIRU Adeno-associated virus - 1 3 0.8249
Capsid protein Q9WBP8 Q9WBP8_9VIRU Adeno-associated virus - 1 3 0.8249
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A Q9QYJ6 PDE10_RAT Rattus norvegicus 3 0.8248
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A Q9QYJ6 PDE10_RAT Rattus norvegicus 3 0.8248
Beta-secretase 1 P56817 BACE1_HUMAN Homo sapiens 3 0.8248
Beta-secretase 1 P56817 BACE1_HUMAN Homo sapiens 3 0.8248
Carbonic anhydrase 2 P00918 CAH2_HUMAN Homo sapiens 3 0.8246
Bifunctional protein GlmU P43889 GLMU_HAEIN Haemophilus influenzae 3 0.8246
Fibroblast growth factor receptor 2 P21802 FGFR2_HUMAN Homo sapiens 3 0.8246
Carbonic anhydrase 2 P00918 CAH2_HUMAN Homo sapiens 3 0.8246
Bifunctional protein GlmU P43889 GLMU_HAEIN Haemophilus influenzae 3 0.8246
Fibroblast growth factor receptor 2 P21802 FGFR2_HUMAN Homo sapiens 3 0.8246
tyrosine--tRNA ligase Q4QFJ7 Q4QFJ7_LEIMA Leishmania major 3 0.8240
tyrosine--tRNA ligase Q4QFJ7 Q4QFJ7_LEIMA Leishmania major 3 0.8240
Ephrin type-B receptor 2 P54763 EPHB2_MOUSE Mus musculus 3 0.8239
Ephrin type-B receptor 2 P54763 EPHB2_MOUSE Mus musculus 3 0.8239
Heat shock protein HSP 90-alpha P07900 HS90A_HUMAN Homo sapiens 3 0.8237
Heat shock protein HSP 90-alpha P07900 HS90A_HUMAN Homo sapiens 3 0.8237
Photosynthetic reaction center cytochrome c subunit P07173 CYCR_BLAVI Blastochloris viridis 3 0.8234
Photosynthetic reaction center cytochrome c subunit P07173 CYCR_BLAVI Blastochloris viridis 3 0.8234
Serine/threonine-protein kinase SKY1 Q03656 SKY1_YEAST Saccharomyces cerevisiae 3 0.8229
Serine/threonine-protein kinase SKY1 Q03656 SKY1_YEAST Saccharomyces cerevisiae 3 0.8229
Nitric oxide synthase, inducible P29477 NOS2_MOUSE Mus musculus 3 0.8219
Nitric oxide synthase, inducible P29477 NOS2_MOUSE Mus musculus 3 0.8219
Pteridine reductase O76290 O76290_TRYBB Trypanosoma brucei brucei 3 0.8212
Mycocyclosin synthase P9WPP7 CP121_MYCTU Mycobacterium tuberculosis 3 0.8212
Mycocyclosin synthase P9WPP7 CP121_MYCTU Mycobacterium tuberculosis 3 0.8212
Pteridine reductase O76290 O76290_TRYBB Trypanosoma brucei brucei 3 0.8212
ADP-ribosylation factor 1 P84080 ARF1_BOVIN Bos taurus 3 0.8206
ADP-ribosylation factor 1 P84080 ARF1_BOVIN Bos taurus 3 0.8206
Ribosyldihydronicotinamide dehydrogenase [quinone] P16083 NQO2_HUMAN Homo sapiens 3 0.8196
Ribosyldihydronicotinamide dehydrogenase [quinone] P16083 NQO2_HUMAN Homo sapiens 3 0.8196
Prothrombin P00734 THRB_HUMAN Homo sapiens 3 0.8192
Prothrombin P00734 THRB_HUMAN Homo sapiens 3 0.8192
Aldo-keto reductase family 1 member C2 P52895 AK1C2_HUMAN Homo sapiens 3 0.8189
Aldo-keto reductase family 1 member C2 P52895 AK1C2_HUMAN Homo sapiens 3 0.8189
Carbonyl reductase [NADPH] 1 P16152 CBR1_HUMAN Homo sapiens 3 0.8187
Carbonyl reductase [NADPH] 1 P16152 CBR1_HUMAN Homo sapiens 3 0.8187
Liver carboxylesterase 1 P23141 EST1_HUMAN Homo sapiens 3 0.8168
Liver carboxylesterase 1 P23141 EST1_HUMAN Homo sapiens 3 0.8168
Serine/threonine-protein kinase pim-1 P11309 PIM1_HUMAN Homo sapiens 3 0.8165
Serine/threonine-protein kinase pim-1 P11309 PIM1_HUMAN Homo sapiens 3 0.8165
Cyclin-dependent kinase 2 P24941 CDK2_HUMAN Homo sapiens 3 0.8164
Cyclin-dependent kinase 2 P24941 CDK2_HUMAN Homo sapiens 3 0.8164
Nitric oxide synthase, inducible P29477 NOS2_MOUSE Mus musculus 3 0.8141
Nitric oxide synthase, inducible P29477 NOS2_MOUSE Mus musculus 3 0.8141
Gag-Pol polyprotein P12497 POL_HV1N5 Human immunodeficiency virus type 1 group M subtype B 3 0.8138
Gag-Pol polyprotein P12497 POL_HV1N5 Human immunodeficiency virus type 1 group M subtype B 3 0.8138
Cyclin-dependent kinase 2 P24941 CDK2_HUMAN Homo sapiens 3 0.8136
Cyclin-dependent kinase 2 P24941 CDK2_HUMAN Homo sapiens 3 0.8136
Mitogen-activated protein kinase 14 Q16539 MK14_HUMAN Homo sapiens 3 0.8136
Mitogen-activated protein kinase 14 Q16539 MK14_HUMAN Homo sapiens 3 0.8136
Chitinase Q54276 Q54276_SERMA Serratia marcescens 3 0.8130
Chitinase Q54276 Q54276_SERMA Serratia marcescens 3 0.8130
Pyridoxal kinase P82197 PDXK_SHEEP Ovis aries 3 0.8124
Pyridoxal kinase P82197 PDXK_SHEEP Ovis aries 3 0.8124
Beta-secretase 1 P56817 BACE1_HUMAN Homo sapiens 3 0.8121
Beta-secretase 1 P56817 BACE1_HUMAN Homo sapiens 3 0.8121
Adenylate cyclase 2 A0A2U2H3Y1 A0A384LKY8_YERPE Yersinia pestis 3 0.8100
Adenylate cyclase 2 A0A2U2H3Y1 A0A384LKY8_YERPE Yersinia pestis 3 0.8100
Poly [ADP-ribose] polymerase 1 P09874 PARP1_HUMAN Homo sapiens 3 0.8094
Poly [ADP-ribose] polymerase 1 P09874 PARP1_HUMAN Homo sapiens 3 0.8094
Queuine tRNA-ribosyltransferase P28720 TGT_ZYMMO Zymomonas mobilis subsp. mobilis 3 0.8093
Queuine tRNA-ribosyltransferase P28720 TGT_ZYMMO Zymomonas mobilis subsp. mobilis 3 0.8093
Biotin carboxylase P43873 ACCC_HAEIN Haemophilus influenzae 3 0.8088
Biotin carboxylase P43873 ACCC_HAEIN Haemophilus influenzae 3 0.8088
Thymidylate synthase P0A884 TYSY_ECOLI Escherichia coli 2 0.8085
Thymidylate synthase P0A884 TYSY_ECOLI Escherichia coli 2 0.8085
Myosin heavy chain kinase A P42527 MHCKA_DICDI Dictyostelium discoideum 3 0.8084
Myosin heavy chain kinase A P42527 MHCKA_DICDI Dictyostelium discoideum 3 0.8084
Hematopoietic prostaglandin D synthase O60760 HPGDS_HUMAN Homo sapiens 3 0.8077
Hematopoietic prostaglandin D synthase O60760 HPGDS_HUMAN Homo sapiens 3 0.8077
Mitogen-activated protein kinase 10 P53779 MK10_HUMAN Homo sapiens 3 0.8073
Mitogen-activated protein kinase 10 P53779 MK10_HUMAN Homo sapiens 3 0.8073
Mitogen-activated protein kinase 14 Q16539 MK14_HUMAN Homo sapiens 4 0.8071
Mitogen-activated protein kinase 14 Q16539 MK14_HUMAN Homo sapiens 4 0.8071
HTH-type transcriptional regulator EthR P9WMC1 ETHR_MYCTU Mycobacterium tuberculosis 3 0.8067
HTH-type transcriptional regulator EthR P9WMC1 ETHR_MYCTU Mycobacterium tuberculosis 3 0.8067
Ribosyldihydronicotinamide dehydrogenase [quinone] P16083 NQO2_HUMAN Homo sapiens 3 0.8062
Ribosyldihydronicotinamide dehydrogenase [quinone] P16083 NQO2_HUMAN Homo sapiens 3 0.8062
Beta-secretase 1 P56817 BACE1_HUMAN Homo sapiens 3 0.8060
Beta-secretase 1 P56817 BACE1_HUMAN Homo sapiens 3 0.8060
Prothrombin P00734 THRB_HUMAN Homo sapiens 3 0.8039
Prothrombin P00734 THRB_HUMAN Homo sapiens 3 0.8039
Beta-galactoside alpha-2,6-sialyltransferase 1 P15907 SIAT1_HUMAN Homo sapiens 4 0.8031
Beta-galactoside alpha-2,6-sialyltransferase 1 P15907 SIAT1_HUMAN Homo sapiens 4 0.8031
Beta-galactoside-specific lectin 1 P81446 ML1_VISAL Viscum album 3 0.8029
Beta-galactoside-specific lectin 1 P81446 ML1_VISAL Viscum album 3 0.8029
HTH-type transcriptional repressor PurR P0ACP7 PURR_ECOLI Escherichia coli 3 0.8027
HTH-type transcriptional repressor PurR P0ACP7 PURR_ECOLI Escherichia coli 3 0.8027
S-norcoclaurine synthase Q67A25 NCS_THLFG Thalictrum flavum subsp. glaucum 3 0.8026
S-norcoclaurine synthase Q67A25 NCS_THLFG Thalictrum flavum subsp. glaucum 3 0.8026
Proto-oncogene tyrosine-protein kinase receptor Ret P07949 RET_HUMAN Homo sapiens 3 0.8024
Proto-oncogene tyrosine-protein kinase receptor Ret P07949 RET_HUMAN Homo sapiens 3 0.8024
Stromelysin-1 P08254 MMP3_HUMAN Homo sapiens 3 0.8021
Stromelysin-1 P08254 MMP3_HUMAN Homo sapiens 3 0.8021
Tryptase alpha/beta-1 Q15661 TRYB1_HUMAN Homo sapiens 3 0.8017
Tryptase alpha/beta-1 Q15661 TRYB1_HUMAN Homo sapiens 3 0.8017
DNA gyrase subunit B Q839Z1 GYRB_ENTFA Enterococcus faecalis 3 0.8010
DNA gyrase subunit B Q839Z1 GYRB_ENTFA Enterococcus faecalis 3 0.8010
N-acetyltransferase domain-containing protein Q9HV14 Q9HV14_PSEAE Pseudomonas aeruginosa 2 0.7998
N-acetyltransferase domain-containing protein Q9HV14 Q9HV14_PSEAE Pseudomonas aeruginosa 2 0.7998
Biotin carboxylase P24182 ACCC_ECOLI Escherichia coli 3 0.7997
Biotin carboxylase P24182 ACCC_ECOLI Escherichia coli 3 0.7997
Cyclin-dependent kinase 2 P24941 CDK2_HUMAN Homo sapiens 3 0.7993
Cyclin-dependent kinase 2 P24941 CDK2_HUMAN Homo sapiens 3 0.7993
Heat shock protein HSP 90-alpha P07900 HS90A_HUMAN Homo sapiens 3 0.7992
Beta-secretase 1 P56817 BACE1_HUMAN Homo sapiens 3 0.7992
Heat shock protein HSP 90-alpha P07900 HS90A_HUMAN Homo sapiens 3 0.7992
Beta-secretase 1 P56817 BACE1_HUMAN Homo sapiens 3 0.7992
HTH-type transcriptional regulator TtgR Q9AIU0 TTGR_PSEPT Pseudomonas putida 3 0.7987
HTH-type transcriptional regulator TtgR Q9AIU0 TTGR_PSEPT Pseudomonas putida 3 0.7987
Peroxidase C1A P00433 PER1A_ARMRU Armoracia rusticana 3 0.7985
Peroxidase C1A P00433 PER1A_ARMRU Armoracia rusticana 3 0.7985
Phosphotriesterase Q5KZU5 Q5KZU5_GEOKA Geobacillus kaustophilus 3 0.7980
Phosphotriesterase Q5KZU5 Q5KZU5_GEOKA Geobacillus kaustophilus 3 0.7980
Glycogen synthase kinase-3 beta P49841 GSK3B_HUMAN Homo sapiens 3 0.7972
Glycogen synthase kinase-3 beta P49841 GSK3B_HUMAN Homo sapiens 3 0.7972
11-beta-hydroxysteroid dehydrogenase 1 P28845 DHI1_HUMAN Homo sapiens 3 0.7970
11-beta-hydroxysteroid dehydrogenase 1 P28845 DHI1_HUMAN Homo sapiens 3 0.7970
Urokinase-type plasminogen activator P00749 UROK_HUMAN Homo sapiens 3 0.7956
Urokinase-type plasminogen activator P00749 UROK_HUMAN Homo sapiens 3 0.7956
Cytohesin-2 Q99418 CYH2_HUMAN Homo sapiens 3 0.7954
Cytohesin-2 Q99418 CYH2_HUMAN Homo sapiens 3 0.7954
Heat shock protein HSP 90-alpha P07900 HS90A_HUMAN Homo sapiens 3 0.7949
Heat shock protein HSP 90-alpha P07900 HS90A_HUMAN Homo sapiens 3 0.7949
Heat shock protein HSP 90-alpha P07900 HS90A_HUMAN Homo sapiens 3 0.7946
Beta-secretase 1 P56817 BACE1_HUMAN Homo sapiens 3 0.7946
Heat shock protein HSP 90-alpha P07900 HS90A_HUMAN Homo sapiens 3 0.7946
Beta-secretase 1 P56817 BACE1_HUMAN Homo sapiens 3 0.7946
Actin-related protein 3 P61157 ARP3_BOVIN Bos taurus 3 0.7945
NADPH dehydrogenase 1 Q02899 OYE1_SACPS Saccharomyces pastorianus 3 0.7945
NADPH dehydrogenase 1 Q02899 OYE1_SACPS Saccharomyces pastorianus 3 0.7945
Actin-related protein 3 P61157 ARP3_BOVIN Bos taurus 3 0.7945
Casein kinase II subunit alpha P68400 CSK21_HUMAN Homo sapiens 3 0.7934
Casein kinase II subunit alpha P68400 CSK21_HUMAN Homo sapiens 3 0.7934
Transcriptional regulator, PadR-like family A2RI36 A2RI36_LACLM Lactococcus lactis subsp. cremoris 2 0.7919
Transcriptional regulator, PadR-like family A2RI36 A2RI36_LACLM Lactococcus lactis subsp. cremoris 2 0.7919
Protoporphyrinogen oxidase P50336 PPOX_HUMAN Homo sapiens 3 0.7916
Protoporphyrinogen oxidase P50336 PPOX_HUMAN Homo sapiens 3 0.7916
Mitogen-activated protein kinase 14 Q16539 MK14_HUMAN Homo sapiens 3 0.7914
Mitogen-activated protein kinase 14 Q16539 MK14_HUMAN Homo sapiens 3 0.7914
Prolyl endopeptidase P23687 PPCE_PIG Sus scrofa 3 0.7913
Prolyl endopeptidase P23687 PPCE_PIG Sus scrofa 3 0.7913
Lactoylglutathione lyase Q9CPU0 LGUL_MOUSE Mus musculus 2 0.7910
Heat shock protein HSP 90-alpha P07900 HS90A_HUMAN Homo sapiens 3 0.7910
Lactoylglutathione lyase Q9CPU0 LGUL_MOUSE Mus musculus 2 0.7910
Heat shock protein HSP 90-alpha P07900 HS90A_HUMAN Homo sapiens 3 0.7910
Queuine tRNA-ribosyltransferase P28720 TGT_ZYMMO Zymomonas mobilis subsp. mobilis 4 0.7904
Queuine tRNA-ribosyltransferase P28720 TGT_ZYMMO Zymomonas mobilis subsp. mobilis 4 0.7904
Prothrombin P00734 THRB_HUMAN Homo sapiens 3 0.7895
Prothrombin P00734 THRB_HUMAN Homo sapiens 3 0.7895
Orf1ab polyprotein Q6T1E9 Q6T1E9_CVHSA SARS coronavirus CUHK-L2 3 0.7893
Orf1ab polyprotein Q6T1E9 Q6T1E9_CVHSA SARS coronavirus CUHK-L2 3 0.7893
Nitric oxide synthase, inducible P29477 NOS2_MOUSE Mus musculus 3 0.7891
Nitric oxide synthase, inducible P29477 NOS2_MOUSE Mus musculus 3 0.7891
Prothrombin P00734 THRB_HUMAN Homo sapiens 3 0.7883
Prothrombin P00734 THRB_HUMAN Homo sapiens 3 0.7883
Poly [ADP-ribose] polymerase tankyrase-2 Q9H2K2 TNKS2_HUMAN Homo sapiens 3 0.7879
Poly [ADP-ribose] polymerase tankyrase-2 Q9H2K2 TNKS2_HUMAN Homo sapiens 3 0.7879
Nickel-binding periplasmic protein P33590 NIKA_ECOLI Escherichia coli 2 0.7875
Nickel-binding periplasmic protein P33590 NIKA_ECOLI Escherichia coli 2 0.7875
NAD(P)H dehydrogenase [quinone] 1 P15559 NQO1_HUMAN Homo sapiens 4 0.7875
NAD(P)H dehydrogenase [quinone] 1 P15559 NQO1_HUMAN Homo sapiens 4 0.7875
Urokinase-type plasminogen activator P00749 UROK_HUMAN Homo sapiens 3 0.7873
Urokinase-type plasminogen activator P00749 UROK_HUMAN Homo sapiens 3 0.7873
Ribosyldihydronicotinamide dehydrogenase [quinone] P16083 NQO2_HUMAN Homo sapiens 3 0.7872
Ribosyldihydronicotinamide dehydrogenase [quinone] P16083 NQO2_HUMAN Homo sapiens 3 0.7872
RIO-type serine/threonine-protein kinase Rio1 O28471 RIO1_ARCFU Archaeoglobus fulgidus 3 0.7866
RIO-type serine/threonine-protein kinase Rio1 O28471 RIO1_ARCFU Archaeoglobus fulgidus 3 0.7866
Carbonic anhydrase 2 P00918 CAH2_HUMAN Homo sapiens 3 0.7866
Carbonic anhydrase 2 P00918 CAH2_HUMAN Homo sapiens 3 0.7866
NAD-dependent protein deacetylase Q9WYW0 NPD_THEMA Thermotoga maritima 3 0.7860
NAD-dependent protein deacetylase Q9WYW0 NPD_THEMA Thermotoga maritima 3 0.7860
Genome polyprotein P26663 POLG_HCVBK Hepatitis C virus genotype 1b 3 0.7859
Ribosyldihydronicotinamide dehydrogenase [quinone] P16083 NQO2_HUMAN Homo sapiens 3 0.7859
Genome polyprotein P26663 POLG_HCVBK Hepatitis C virus genotype 1b 3 0.7859
Ribosyldihydronicotinamide dehydrogenase [quinone] P16083 NQO2_HUMAN Homo sapiens 3 0.7859
Cytochrome P450 3A4 P08684 CP3A4_HUMAN Homo sapiens 3 0.7858
Cytochrome P450 3A4 P08684 CP3A4_HUMAN Homo sapiens 3 0.7858
Heat shock protein HSP 90-alpha P07900 HS90A_HUMAN Homo sapiens 3 0.7857
Heat shock protein HSP 90-alpha P07900 HS90A_HUMAN Homo sapiens 3 0.7857
Prothrombin P00734 THRB_HUMAN Homo sapiens 3 0.7854
Prothrombin P00734 THRB_HUMAN Homo sapiens 3 0.7854
Glutamate receptor 2 P19491 GRIA2_RAT Rattus norvegicus 3 0.7853
Actin-related protein 3 P61157 ARP3_BOVIN Bos taurus 3 0.7853
Angiopoietin-1 receptor Q02763 TIE2_HUMAN Homo sapiens 3 0.7853
Glutamate receptor 2 P19491 GRIA2_RAT Rattus norvegicus 3 0.7853
Actin-related protein 3 P61157 ARP3_BOVIN Bos taurus 3 0.7853
Angiopoietin-1 receptor Q02763 TIE2_HUMAN Homo sapiens 3 0.7853
Dihydrofolate reductase P00374 DYR_HUMAN Homo sapiens 3 0.7849
Dihydrofolate reductase P00374 DYR_HUMAN Homo sapiens 3 0.7849
Cyclin-dependent kinase 2 P24941 CDK2_HUMAN Homo sapiens 3 0.7848
Cyclin-dependent kinase 2 P24941 CDK2_HUMAN Homo sapiens 3 0.7848
NAD-capped RNA hydrolase NudC P32664 NUDC_ECOLI Escherichia coli 3 0.7846
Protein mono-ADP-ribosyltransferase PARP3 Q9Y6F1 PARP3_HUMAN Homo sapiens 3 0.7846
NAD-capped RNA hydrolase NudC P32664 NUDC_ECOLI Escherichia coli 3 0.7846
Protein mono-ADP-ribosyltransferase PARP3 Q9Y6F1 PARP3_HUMAN Homo sapiens 3 0.7846
Glycogen phosphorylase, liver form P06737 PYGL_HUMAN Homo sapiens 3 0.7845
Prolyl endopeptidase P23687 PPCE_PIG Sus scrofa 3 0.7845
Prolyl endopeptidase P23687 PPCE_PIG Sus scrofa 3 0.7845
Glycogen phosphorylase, liver form P06737 PYGL_HUMAN Homo sapiens 3 0.7845
3-hydroxyisobutyryl-CoA hydrolase, mitochondrial Q6NVY1 HIBCH_HUMAN Homo sapiens 3 0.7825
3-hydroxyisobutyryl-CoA hydrolase, mitochondrial Q6NVY1 HIBCH_HUMAN Homo sapiens 3 0.7825
Genome polyprotein P26663 POLG_HCVBK Hepatitis C virus genotype 1b 3 0.7822
Genome polyprotein P26663 POLG_HCVBK Hepatitis C virus genotype 1b 3 0.7822
Proto-oncogene tyrosine-protein kinase Src P00523 SRC_CHICK Gallus gallus 3 0.7811
Proto-oncogene tyrosine-protein kinase Src P00523 SRC_CHICK Gallus gallus 3 0.7811
Kinesin-like protein KIF11 P52732 KIF11_HUMAN Homo sapiens 3 0.7798
Kinesin-like protein KIF11 P52732 KIF11_HUMAN Homo sapiens 3 0.7798
Cyclin-dependent kinase 2 P24941 CDK2_HUMAN Homo sapiens 3 0.7798
Cyclin-dependent kinase 2 P24941 CDK2_HUMAN Homo sapiens 3 0.7798
Glycogen synthase kinase-3 beta P49841 GSK3B_HUMAN Homo sapiens 3 0.7795
Glycogen synthase kinase-3 beta P49841 GSK3B_HUMAN Homo sapiens 3 0.7795
Nitric oxide synthase, inducible P29477 NOS2_MOUSE Mus musculus 3 0.7794
Nitric oxide synthase, inducible P29477 NOS2_MOUSE Mus musculus 3 0.7794
Histone deacetylase 8 Q9BY41 HDAC8_HUMAN Homo sapiens 2 0.7789
Histone deacetylase 8 Q9BY41 HDAC8_HUMAN Homo sapiens 2 0.7789
Kelch-like ECH-associated protein 1 Q14145 KEAP1_HUMAN Homo sapiens 3 0.7788
Kelch-like ECH-associated protein 1 Q14145 KEAP1_HUMAN Homo sapiens 3 0.7788
Thymidylate synthase P00469 TYSY_LACCA Lacticaseibacillus casei 3 0.7784
Thymidylate synthase P00469 TYSY_LACCA Lacticaseibacillus casei 3 0.7784
Serine/threonine-protein kinase Chk2 O96017 CHK2_HUMAN Homo sapiens 3 0.7781
Serine/threonine-protein kinase Chk2 O96017 CHK2_HUMAN Homo sapiens 3 0.7781
Beta-glucuronidase P05804 BGLR_ECOLI Escherichia coli 3 0.7778
Beta-glucuronidase P05804 BGLR_ECOLI Escherichia coli 3 0.7778
Type II methyltransferase M.TaqI P14385 MTTA_THEAQ Thermus aquaticus 3 0.7773
Type II methyltransferase M.TaqI P14385 MTTA_THEAQ Thermus aquaticus 3 0.7773
Nitric oxide synthase, inducible P29477 NOS2_MOUSE Mus musculus 2 0.7771
Nitric oxide synthase, inducible P29477 NOS2_MOUSE Mus musculus 2 0.7771
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial Q15119 PDK2_HUMAN Homo sapiens 3 0.7770
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial Q15119 PDK2_HUMAN Homo sapiens 3 0.7770
Nuclear receptor subfamily 1 group I member 2 O75469 NR1I2_HUMAN Homo sapiens 3 0.7769
Nuclear receptor subfamily 1 group I member 2 O75469 NR1I2_HUMAN Homo sapiens 3 0.7769
Kinesin-like protein KIF11 P52732 KIF11_HUMAN Homo sapiens 3 0.7767
Kinesin-like protein KIF11 P52732 KIF11_HUMAN Homo sapiens 3 0.7767
Thymidylate kinase Q8I4S1 Q8I4S1_PLAF7 Plasmodium falciparum 4 0.7764
Thymidylate kinase Q8I4S1 Q8I4S1_PLAF7 Plasmodium falciparum 4 0.7764
Pteridine reductase, putative Q581W1 Q581W1_TRYB2 Trypanosoma brucei brucei 3 0.7764
Pteridine reductase, putative Q581W1 Q581W1_TRYB2 Trypanosoma brucei brucei 3 0.7764
Threonine synthase 1, chloroplastic Q9S7B5 THRC1_ARATH Arabidopsis thaliana 3 0.7762
Threonine synthase 1, chloroplastic Q9S7B5 THRC1_ARATH Arabidopsis thaliana 3 0.7762
cGMP-dependent protein kinase, putative A5K0N4 A5K0N4_PLAVS Plasmodium vivax 3 0.7760
Aminoglycoside 3'-phosphotransferase AphA1-IAB B0VD92 B0VD92_ACIBY Acinetobacter baumannii 3 0.7760
cGMP-dependent protein kinase, putative A5K0N4 A5K0N4_PLAVS Plasmodium vivax 3 0.7760
Aminoglycoside 3'-phosphotransferase AphA1-IAB B0VD92 B0VD92_ACIBY Acinetobacter baumannii 3 0.7760
Tannase B3Y018 B3Y018_LACPN Lactiplantibacillus plantarum 3 0.7759
Tannase B3Y018 B3Y018_LACPN Lactiplantibacillus plantarum 3 0.7759
Aldo-keto reductase family 1 member C3 P42330 AK1C3_HUMAN Homo sapiens 2 0.7758
Aldo-keto reductase family 1 member C3 P42330 AK1C3_HUMAN Homo sapiens 2 0.7758
Poly [ADP-ribose] polymerase tankyrase-2 Q9H2K2 TNKS2_HUMAN Homo sapiens 3 0.7754
Poly [ADP-ribose] polymerase tankyrase-2 Q9H2K2 TNKS2_HUMAN Homo sapiens 3 0.7754
Class 10 plant pathogenesis-related protein 2B Q9LLQ2 P102B_LUPLU Lupinus luteus 2 0.7751
Class 10 plant pathogenesis-related protein 2B Q9LLQ2 P102B_LUPLU Lupinus luteus 2 0.7751
Thymidylate kinase Q8I4S1 Q8I4S1_PLAF7 Plasmodium falciparum 4 0.7750
Thymidylate kinase Q8I4S1 Q8I4S1_PLAF7 Plasmodium falciparum 4 0.7750
Polymerase acidic protein P03433 PA_I34A1 Influenza A virus 2 0.7749
Polymerase acidic protein P03433 PA_I34A1 Influenza A virus 2 0.7749
Aurora kinase B-A Q6DE08 AUKBA_XENLA Xenopus laevis 3 0.7739
Aurora kinase B-A Q6DE08 AUKBA_XENLA Xenopus laevis 3 0.7739
Nicotinamide phosphoribosyltransferase P43490 NAMPT_HUMAN Homo sapiens 3 0.7738
Nicotinamide phosphoribosyltransferase P43490 NAMPT_HUMAN Homo sapiens 3 0.7738
Aminopeptidase N P04825 AMPN_ECOLI Escherichia coli 3 0.7733
Aminopeptidase N P04825 AMPN_ECOLI Escherichia coli 3 0.7733
Vascular endothelial growth factor receptor 2 P35968 VGFR2_HUMAN Homo sapiens 3 0.7732
Vascular endothelial growth factor receptor 2 P35968 VGFR2_HUMAN Homo sapiens 3 0.7732
Serine/threonine-protein kinase 24 Q9Y6E0 STK24_HUMAN Homo sapiens 3 0.7728
Serine/threonine-protein kinase 24 Q9Y6E0 STK24_HUMAN Homo sapiens 3 0.7728
Nicotinamide phosphoribosyltransferase P43490 NAMPT_HUMAN Homo sapiens 3 0.7727
Nicotinamide phosphoribosyltransferase P43490 NAMPT_HUMAN Homo sapiens 3 0.7727
Genome polyprotein C0LMU0 C0LMU0_9FLAV dengue virus type 3 3 0.7727
Genome polyprotein C0LMU0 C0LMU0_9FLAV dengue virus type 3 3 0.7727
Cyclic GMP-AMP synthase Q8C6L5 CGAS_MOUSE Mus musculus 3 0.7718
Cyclic GMP-AMP synthase Q8C6L5 CGAS_MOUSE Mus musculus 3 0.7718
Cyclin-dependent kinase 2 P24941 CDK2_HUMAN Homo sapiens 3 0.7718
Cyclin-dependent kinase 2 P24941 CDK2_HUMAN Homo sapiens 3 0.7718
Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase Q05603 COBT_SALTY Salmonella typhimurium 3 0.7717
Mycocyclosin synthase P9WPP7 CP121_MYCTU Mycobacterium tuberculosis 3 0.7717
Mycocyclosin synthase P9WPP7 CP121_MYCTU Mycobacterium tuberculosis 3 0.7717
Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase Q05603 COBT_SALTY Salmonella typhimurium 3 0.7717
Thymidylate synthase P0A886 TYSY_ECO57 Escherichia coli O157:H7 3 0.7714
Thymidylate synthase P0A886 TYSY_ECO57 Escherichia coli O157:H7 3 0.7714
Dihydrofolate reductase P00374 DYR_HUMAN Homo sapiens 3 0.7712
Dihydrofolate reductase P00374 DYR_HUMAN Homo sapiens 3 0.7712
Casein kinase II subunit alpha P28523 CSK2A_MAIZE Zea mays 3 0.7712
Casein kinase II subunit alpha P28523 CSK2A_MAIZE Zea mays 3 0.7712
Pol protein Q000H7 Q000H7_9HIV1 Human immunodeficiency virus 1 3 0.7711
Pol protein Q000H7 Q000H7_9HIV1 Human immunodeficiency virus 1 3 0.7711
Beta-secretase 2 Q9Y5Z0 BACE2_HUMAN Homo sapiens 2 0.7709
Beta-secretase 2 Q9Y5Z0 BACE2_HUMAN Homo sapiens 2 0.7709
Matrilysin P09237 MMP7_HUMAN Homo sapiens 3 0.7707
Matrilysin P09237 MMP7_HUMAN Homo sapiens 3 0.7707
Prothrombin P00734 THRB_HUMAN Homo sapiens 3 0.7705
Prothrombin P00734 THRB_HUMAN Homo sapiens 3 0.7705
Pteridine reductase 1 Q01782 PTR1_LEIMA Leishmania major 3 0.7701
Pteridine reductase 1 Q01782 PTR1_LEIMA Leishmania major 3 0.7701
Mitogen-activated protein kinase 14 P47811 MK14_MOUSE Mus musculus 3 0.7695
Mitogen-activated protein kinase 14 P47811 MK14_MOUSE Mus musculus 3 0.7695
Ephrin type-A receptor 3 P29320 EPHA3_HUMAN Homo sapiens 3 0.7694
Ephrin type-A receptor 3 P29320 EPHA3_HUMAN Homo sapiens 3 0.7694
Serine/threonine-protein kinase Chk1 O14757 CHK1_HUMAN Homo sapiens 3 0.7688
Cyclin-dependent kinase 2 P24941 CDK2_HUMAN Homo sapiens 3 0.7688
Cyclin-dependent kinase 2 P24941 CDK2_HUMAN Homo sapiens 3 0.7688
Serine/threonine-protein kinase Chk1 O14757 CHK1_HUMAN Homo sapiens 3 0.7688
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform P48736 PK3CG_HUMAN Homo sapiens 3 0.7686
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform P48736 PK3CG_HUMAN Homo sapiens 3 0.7686
ADP-ribosylation factor 1 P84077 ARF1_HUMAN Homo sapiens 2 0.7682
ADP-ribosylation factor 1 P84077 ARF1_HUMAN Homo sapiens 2 0.7682
Ephrin type-B receptor 4 P54760 EPHB4_HUMAN Homo sapiens 3 0.7681
Ephrin type-B receptor 4 P54760 EPHB4_HUMAN Homo sapiens 3 0.7681
Soluble cytochrome b562 P0ABE7 C562_ECOLX Escherichia coli 3 0.7677
Soluble cytochrome b562 P0ABE7 C562_ECOLX Escherichia coli 3 0.7677
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform P48736 PK3CG_HUMAN Homo sapiens 3 0.7676
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform P48736 PK3CG_HUMAN Homo sapiens 3 0.7676
RAC-alpha serine/threonine-protein kinase P31749 AKT1_HUMAN Homo sapiens 3 0.7674
Poly [ADP-ribose] polymerase 1 P09874 PARP1_HUMAN Homo sapiens 3 0.7674
RAC-alpha serine/threonine-protein kinase P31749 AKT1_HUMAN Homo sapiens 3 0.7674
Ribosyldihydronicotinamide dehydrogenase [quinone] P16083 NQO2_HUMAN Homo sapiens 3 0.7674
Poly [ADP-ribose] polymerase 1 P09874 PARP1_HUMAN Homo sapiens 3 0.7674
Ribosyldihydronicotinamide dehydrogenase [quinone] P16083 NQO2_HUMAN Homo sapiens 3 0.7674
Thymidylate kinase Q8I4S1 Q8I4S1_PLAF7 Plasmodium falciparum 4 0.7673
Thymidylate kinase Q8I4S1 Q8I4S1_PLAF7 Plasmodium falciparum 4 0.7673
Tyrosine-protein kinase Lck P06239 LCK_HUMAN Homo sapiens 3 0.7668
Tyrosine-protein kinase Lck P06239 LCK_HUMAN Homo sapiens 3 0.7668
Protease O38896 O38896_9HIV1 Human immunodeficiency virus 1 2 0.7663
Protease O38896 O38896_9HIV1 Human immunodeficiency virus 1 2 0.7663
Basic phospholipase A2 VRV-PL-VIIIa P59071 PA2B8_DABRR Daboia russelii 3 0.7662
Basic phospholipase A2 VRV-PL-VIIIa P59071 PA2B8_DABRR Daboia russelii 3 0.7662
Beta-lactamase Q79MP6 Q79MP6_PSEAI Pseudomonas aeruginosa 2 0.7658
Beta-lactamase Q79MP6 Q79MP6_PSEAI Pseudomonas aeruginosa 2 0.7658
Poly [ADP-ribose] polymerase 1 P09874 PARP1_HUMAN Homo sapiens 4 0.7656
Poly [ADP-ribose] polymerase 1 P09874 PARP1_HUMAN Homo sapiens 4 0.7656
Heat shock protein 75 kDa, mitochondrial Q12931 TRAP1_HUMAN Homo sapiens 3 0.7653
Heat shock protein 75 kDa, mitochondrial Q12931 TRAP1_HUMAN Homo sapiens 3 0.7653
Glycogen phosphorylase, liver form P06737 PYGL_HUMAN Homo sapiens 3 0.7649
Glycogen phosphorylase, liver form P06737 PYGL_HUMAN Homo sapiens 3 0.7649
Pancreatic alpha-amylase P04746 AMYP_HUMAN Homo sapiens 2 0.7647
Pancreatic alpha-amylase P04746 AMYP_HUMAN Homo sapiens 2 0.7647
Casein kinase I isoform gamma-3 Q9Y6M4 KC1G3_HUMAN Homo sapiens 3 0.7644
Casein kinase I isoform gamma-3 Q9Y6M4 KC1G3_HUMAN Homo sapiens 3 0.7644
Macrophage colony-stimulating factor 1 receptor P07333 CSF1R_HUMAN Homo sapiens 3 0.7640
Macrophage colony-stimulating factor 1 receptor P07333 CSF1R_HUMAN Homo sapiens 3 0.7640
Stromelysin-1 P08254 MMP3_HUMAN Homo sapiens 4 0.7639
Stromelysin-1 P08254 MMP3_HUMAN Homo sapiens 4 0.7639
High affinity 3',5'-cyclic-AMP phosphodiesterase 7A Q13946 PDE7A_HUMAN Homo sapiens 3 0.7637
High affinity 3',5'-cyclic-AMP phosphodiesterase 7A Q13946 PDE7A_HUMAN Homo sapiens 3 0.7637
High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A O76083 PDE9A_HUMAN Homo sapiens 3 0.7632
High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A O76083 PDE9A_HUMAN Homo sapiens 3 0.7632
Soluble cytochrome b562 P0ABE7 C562_ECOLX Escherichia coli 2 0.7629
Soluble cytochrome b562 P0ABE7 C562_ECOLX Escherichia coli 2 0.7629
Ribosyldihydronicotinamide dehydrogenase [quinone] P16083 NQO2_HUMAN Homo sapiens 3 0.7625
Ribosyldihydronicotinamide dehydrogenase [quinone] P16083 NQO2_HUMAN Homo sapiens 3 0.7625
Gag-Pol polyprotein P05896 POL_SIVM1 Simian immunodeficiency virus 3 0.7616
Beta-secretase 1 P56817 BACE1_HUMAN Homo sapiens 3 0.7616
Gag-Pol polyprotein P05896 POL_SIVM1 Simian immunodeficiency virus 3 0.7616
Beta-secretase 1 P56817 BACE1_HUMAN Homo sapiens 3 0.7616
Mitogen-activated protein kinase 8 P45983 MK08_HUMAN Homo sapiens 3 0.7613
Mitogen-activated protein kinase 8 P45983 MK08_HUMAN Homo sapiens 3 0.7613
4-hydroxyphenylacetate 3-monooxygenase Q8YHT7 Q8YHT7_BRUME Brucella melitensis biotype 1 2 0.7608
4-hydroxyphenylacetate 3-monooxygenase Q8YHT7 Q8YHT7_BRUME Brucella melitensis biotype 1 2 0.7608
Endoplasmic reticulum aminopeptidase 2 Q6P179 ERAP2_HUMAN Homo sapiens 2 0.7608
Endoplasmic reticulum aminopeptidase 2 Q6P179 ERAP2_HUMAN Homo sapiens 2 0.7608
Casein kinase II subunit alpha P68400 CSK21_HUMAN Homo sapiens 3 0.7607
Casein kinase II subunit alpha P68400 CSK21_HUMAN Homo sapiens 3 0.7607
Heat shock protein HSP 90-alpha P07900 HS90A_HUMAN Homo sapiens 3 0.7606
Heat shock protein HSP 90-alpha P07900 HS90A_HUMAN Homo sapiens 3 0.7606
ATP-dependent molecular chaperone HSP82 P02829 HSP82_YEAST Saccharomyces cerevisiae 2 0.7603
ATP-dependent molecular chaperone HSP82 P02829 HSP82_YEAST Saccharomyces cerevisiae 2 0.7603
Carbonic anhydrase 2 P00918 CAH2_HUMAN Homo sapiens 2 0.7600
Soluble cytochrome b562 P0ABE7 C562_ECOLX Escherichia coli 2 0.7600
Carbonic anhydrase 2 P00918 CAH2_HUMAN Homo sapiens 2 0.7600
Soluble cytochrome b562 P0ABE7 C562_ECOLX Escherichia coli 2 0.7600
Cytosolic purine 5'-nucleotidase P49902 5NTC_HUMAN Homo sapiens 4 0.7599
Cytosolic purine 5'-nucleotidase P49902 5NTC_HUMAN Homo sapiens 2 0.7599
Cytosolic purine 5'-nucleotidase P49902 5NTC_HUMAN Homo sapiens 4 0.7599
Cytosolic purine 5'-nucleotidase P49902 5NTC_HUMAN Homo sapiens 2 0.7599
Mitogen-activated protein kinase kinase kinase 5 Q99683 M3K5_HUMAN Homo sapiens 3 0.7594
Mitogen-activated protein kinase kinase kinase 5 Q99683 M3K5_HUMAN Homo sapiens 3 0.7594
Gag-Pol polyprotein P12497 POL_HV1N5 Human immunodeficiency virus type 1 group M subtype B 2 0.7593
Gag-Pol polyprotein P12497 POL_HV1N5 Human immunodeficiency virus type 1 group M subtype B 2 0.7593
Interleukin-1 receptor-associated kinase 4 Q9NWZ3 IRAK4_HUMAN Homo sapiens 3 0.7591
Interleukin-1 receptor-associated kinase 4 Q9NWZ3 IRAK4_HUMAN Homo sapiens 3 0.7591
ADP compounds hydrolase NudE P45799 NUDE_ECOLI Escherichia coli 3 0.7590
Tetracycline repressor protein class H P51561 TETR8_PASMD Pasteurella multocida 2 0.7590
Tetracycline repressor protein class H P51561 TETR8_PASMD Pasteurella multocida 2 0.7590
ADP compounds hydrolase NudE P45799 NUDE_ECOLI Escherichia coli 3 0.7590
Pteridine reductase O76290 O76290_TRYBB Trypanosoma brucei brucei 3 0.7590
Pteridine reductase O76290 O76290_TRYBB Trypanosoma brucei brucei 3 0.7590
Genome polyprotein P26663 POLG_HCVBK Hepatitis C virus genotype 1b 3 0.7588
Genome polyprotein P26663 POLG_HCVBK Hepatitis C virus genotype 1b 3 0.7588
Serine/threonine-protein kinase Chk1 O14757 CHK1_HUMAN Homo sapiens 3 0.7587
Serine/threonine-protein kinase Chk1 O14757 CHK1_HUMAN Homo sapiens 3 0.7587
Gag-Pol polyprotein P03367 POL_HV1BR Human immunodeficiency virus type 1 group M subtype B 3 0.7586
Gag-Pol polyprotein P03367 POL_HV1BR Human immunodeficiency virus type 1 group M subtype B 3 0.7586
Serine/threonine-protein kinase Chk1 O14757 CHK1_HUMAN Homo sapiens 3 0.7585
Serine/threonine-protein kinase Chk1 O14757 CHK1_HUMAN Homo sapiens 3 0.7585
Pentaerythritol tetranitrate reductase P71278 P71278_ENTCL Enterobacter cloacae 2 0.7584
Pentaerythritol tetranitrate reductase P71278 P71278_ENTCL Enterobacter cloacae 2 0.7584
Beta-1 adrenergic receptor P07700 ADRB1_MELGA Meleagris gallopavo 3 0.7577
Beta-1 adrenergic receptor P07700 ADRB1_MELGA Meleagris gallopavo 3 0.7577
Gag-Pol polyprotein P12497 POL_HV1N5 Human immunodeficiency virus type 1 group M subtype B 3 0.7575
Gag-Pol polyprotein P12497 POL_HV1N5 Human immunodeficiency virus type 1 group M subtype B 3 0.7575
Serine/threonine-protein kinase toxin HipA P23874 HIPA_ECOLI Escherichia coli 3 0.7570
Serine/threonine-protein kinase toxin HipA P23874 HIPA_ECOLI Escherichia coli 3 0.7570
Beta-1 adrenergic receptor P07700 ADRB1_MELGA Meleagris gallopavo 2 0.7568
Beta-1 adrenergic receptor P07700 ADRB1_MELGA Meleagris gallopavo 2 0.7568
Proton-gated ion channel Q7NDN8 GLIC_GLOVI Gloeobacter violaceus 3 0.7566
Proton-gated ion channel Q7NDN8 GLIC_GLOVI Gloeobacter violaceus 3 0.7566
clade A/E 93TH057 HIV-1 gp120 core A0A0M3KKW9 A0A0M3KKW9_9HIV1 Human immunodeficiency virus 1 2 0.7564
clade A/E 93TH057 HIV-1 gp120 core A0A0M3KKW9 A0A0M3KKW9_9HIV1 Human immunodeficiency virus 1 2 0.7564
Pteridine reductase, putative Q581W1 Q581W1_TRYB2 Trypanosoma brucei brucei 3 0.7562
Pteridine reductase, putative Q581W1 Q581W1_TRYB2 Trypanosoma brucei brucei 3 0.7562
Bromodomain adjacent to zinc finger domain protein 2B Q9UIF8 BAZ2B_HUMAN Homo sapiens 3 0.7561
Bromodomain adjacent to zinc finger domain protein 2B Q9UIF8 BAZ2B_HUMAN Homo sapiens 3 0.7561
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial Q15119 PDK2_HUMAN Homo sapiens 3 0.7561
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial Q15119 PDK2_HUMAN Homo sapiens 3 0.7561
Gag-Pol polyprotein P03369 POL_HV1A2 Human immunodeficiency virus type 1 group M subtype B 3 0.7555
Stromelysin-1 P08254 MMP3_HUMAN Homo sapiens 3 0.7555
Gag-Pol polyprotein P03369 POL_HV1A2 Human immunodeficiency virus type 1 group M subtype B 3 0.7555
Pol polyprotein Q90K99 Q90K99_9HIV1 Human immunodeficiency virus 1 4 0.7555
Stromelysin-1 P08254 MMP3_HUMAN Homo sapiens 3 0.7555
Pol polyprotein Q90K99 Q90K99_9HIV1 Human immunodeficiency virus 1 4 0.7555
ALK tyrosine kinase receptor Q9UM73 ALK_HUMAN Homo sapiens 3 0.7553
ALK tyrosine kinase receptor Q9UM73 ALK_HUMAN Homo sapiens 3 0.7553
LIM domain kinase 1 P53667 LIMK1_HUMAN Homo sapiens 3 0.7553
LIM domain kinase 1 P53667 LIMK1_HUMAN Homo sapiens 3 0.7553
Bromodomain-containing protein 2 P25440 BRD2_HUMAN Homo sapiens 2 0.7553
ALK tyrosine kinase receptor Q9UM73 ALK_HUMAN Homo sapiens 3 0.7553
ALK tyrosine kinase receptor Q9UM73 ALK_HUMAN Homo sapiens 3 0.7553
Bromodomain-containing protein 2 P25440 BRD2_HUMAN Homo sapiens 2 0.7553
Albumin P02768 ALBU_HUMAN Homo sapiens 3 0.7551
Albumin P02768 ALBU_HUMAN Homo sapiens 3 0.7551
Ephrin type-B receptor 4 P54760 EPHB4_HUMAN Homo sapiens 3 0.7545
Ephrin type-B receptor 4 P54760 EPHB4_HUMAN Homo sapiens 3 0.7545
Death-associated protein kinase 1 P53355 DAPK1_HUMAN Homo sapiens 3 0.7542
Death-associated protein kinase 1 P53355 DAPK1_HUMAN Homo sapiens 3 0.7542
AcsD Q93AT8 Q93AT8_DICCH Dickeya chrysanthemi 3 0.7538
Tannase B3Y018 B3Y018_LACPN Lactiplantibacillus plantarum 3 0.7538
Tannase B3Y018 B3Y018_LACPN Lactiplantibacillus plantarum 3 0.7538
AcsD Q93AT8 Q93AT8_DICCH Dickeya chrysanthemi 3 0.7538
Serine/threonine-protein kinase Chk1 O14757 CHK1_HUMAN Homo sapiens 3 0.7538
Serine/threonine-protein kinase Chk1 O14757 CHK1_HUMAN Homo sapiens 3 0.7538
Ribosyldihydronicotinamide dehydrogenase [quinone] P16083 NQO2_HUMAN Homo sapiens 3 0.7531
Ribosyldihydronicotinamide dehydrogenase [quinone] P16083 NQO2_HUMAN Homo sapiens 3 0.7531
Mitogen-activated protein kinase 10 P53779 MK10_HUMAN Homo sapiens 3 0.7530
Mitogen-activated protein kinase 10 P53779 MK10_HUMAN Homo sapiens 3 0.7530
Genome polyprotein P26663 POLG_HCVBK Hepatitis C virus genotype 1b 3 0.7526
Genome polyprotein P26663 POLG_HCVBK Hepatitis C virus genotype 1b 3 0.7526
Endoplasmin P41148 ENPL_CANLF Canis lupus familiaris 3 0.7525
Endoplasmin P41148 ENPL_CANLF Canis lupus familiaris 3 0.7525
Antitumor antibiotic C-1027 apoprotein Q06110 CAGA_STRGL Streptomyces globisporus 2 0.7523
Antitumor antibiotic C-1027 apoprotein Q06110 CAGA_STRGL Streptomyces globisporus 2 0.7523
Ribosyldihydronicotinamide dehydrogenase [quinone] P16083 NQO2_HUMAN Homo sapiens 2 0.7520
Leucoanthocyanidin dioxygenase Q96323 LDOX_ARATH Arabidopsis thaliana 4 0.7520
Ribosyldihydronicotinamide dehydrogenase [quinone] P16083 NQO2_HUMAN Homo sapiens 2 0.7520
Leucoanthocyanidin dioxygenase Q96323 LDOX_ARATH Arabidopsis thaliana 4 0.7520
Gag-Pol polyprotein P12497 POL_HV1N5 Human immunodeficiency virus type 1 group M subtype B 2 0.7516
Gag-Pol polyprotein P12497 POL_HV1N5 Human immunodeficiency virus type 1 group M subtype B 2 0.7516
Anthocyanidin 3-O-glucosyltransferase UFGT P51094 UFOG_VITVI Vitis vinifera 4 0.7512
Anthocyanidin 3-O-glucosyltransferase UFGT P51094 UFOG_VITVI Vitis vinifera 4 0.7512
Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase Q05603 COBT_SALTY Salmonella typhimurium 2 0.7511
Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase Q05603 COBT_SALTY Salmonella typhimurium 2 0.7511
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial Q15119 PDK2_HUMAN Homo sapiens 2 0.7509
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial Q15119 PDK2_HUMAN Homo sapiens 2 0.7509
Tyrosine-protein kinase Lck P06239 LCK_HUMAN Homo sapiens 3 0.7507
Tyrosine-protein kinase Lck P06239 LCK_HUMAN Homo sapiens 3 0.7507
Anthocyanidin 3-O-glucosyltransferase UFGT P51094 UFOG_VITVI Vitis vinifera 4 0.7503
Anthocyanidin 3-O-glucosyltransferase UFGT P51094 UFOG_VITVI Vitis vinifera 4 0.7503
ALK tyrosine kinase receptor Q9UM73 ALK_HUMAN Homo sapiens 3 0.7500
ALK tyrosine kinase receptor Q9UM73 ALK_HUMAN Homo sapiens 3 0.7500
RNA-dependent RNA polymerase Q6A562 Q6A562_9VIRU Thosea asigna virus 2 0.7497
RNA-dependent RNA polymerase Q6A562 Q6A562_9VIRU Thosea asigna virus 2 0.7497
Metallo-beta-lactamase type 2 P52699 BLAB_SERMA Serratia marcescens 3 0.7496
Metallo-beta-lactamase type 2 P52699 BLAB_SERMA Serratia marcescens 3 0.7496
Nuclear receptor ROR-beta P45446 RORB_RAT Rattus norvegicus 2 0.7492
Nuclear receptor ROR-beta P45446 RORB_RAT Rattus norvegicus 2 0.7492
APH(2'')-Id O68183 O68183_ENTCA Enterococcus casseliflavus 3 0.7492
APH(2'')-Id O68183 O68183_ENTCA Enterococcus casseliflavus 3 0.7492
Cystathionine gamma-synthase P56069 METB_HELPY Helicobacter pylori 3 0.7491
Cystathionine gamma-synthase P56069 METB_HELPY Helicobacter pylori 3 0.7491
Urokinase-type plasminogen activator P00749 UROK_HUMAN Homo sapiens 2 0.7491
Urokinase-type plasminogen activator P00749 UROK_HUMAN Homo sapiens 2 0.7491
N-acetyltransferase domain-containing protein Q9HV14 Q9HV14_PSEAE Pseudomonas aeruginosa 3 0.7489
Aldehyde dehydrogenase, mitochondrial P05091 ALDH2_HUMAN Homo sapiens 3 0.7489
N-acetyltransferase domain-containing protein Q9HV14 Q9HV14_PSEAE Pseudomonas aeruginosa 3 0.7489
Aldehyde dehydrogenase, mitochondrial P05091 ALDH2_HUMAN Homo sapiens 3 0.7489
11-beta-hydroxysteroid dehydrogenase 1 P28845 DHI1_HUMAN Homo sapiens 3 0.7487
cGMP-dependent 3',5'-cyclic phosphodiesterase O00408 PDE2A_HUMAN Homo sapiens 3 0.7487
11-beta-hydroxysteroid dehydrogenase 1 P28845 DHI1_HUMAN Homo sapiens 3 0.7487
cGMP-dependent 3',5'-cyclic phosphodiesterase O00408 PDE2A_HUMAN Homo sapiens 3 0.7487
histone deacetylase A5H660 A5H660_SCHMA Schistosoma mansoni 3 0.7486
histone deacetylase A5H660 A5H660_SCHMA Schistosoma mansoni 3 0.7486
Secoisolariciresinol dehydrogenase Q94KL8 SILD_PODPE Podophyllum peltatum 3 0.7484
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial Q15119 PDK2_HUMAN Homo sapiens 3 0.7484
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial Q15119 PDK2_HUMAN Homo sapiens 3 0.7484
Secoisolariciresinol dehydrogenase Q94KL8 SILD_PODPE Podophyllum peltatum 3 0.7484
Ephrin type-B receptor 4 P54760 EPHB4_HUMAN Homo sapiens 3 0.7484
Ephrin type-B receptor 4 P54760 EPHB4_HUMAN Homo sapiens 3 0.7484
Peroxisome proliferator-activated receptor gamma P37231 PPARG_HUMAN Homo sapiens 3 0.7483
ALK tyrosine kinase receptor Q9UM73 ALK_HUMAN Homo sapiens 3 0.7483
Peroxisome proliferator-activated receptor gamma P37231 PPARG_HUMAN Homo sapiens 3 0.7483
ALK tyrosine kinase receptor Q9UM73 ALK_HUMAN Homo sapiens 3 0.7483
ALK tyrosine kinase receptor Q9UM73 ALK_HUMAN Homo sapiens 3 0.7482
Urokinase-type plasminogen activator P00749 UROK_HUMAN Homo sapiens 2 0.7482
Urokinase-type plasminogen activator P00749 UROK_HUMAN Homo sapiens 2 0.7482
ALK tyrosine kinase receptor Q9UM73 ALK_HUMAN Homo sapiens 3 0.7482
Endothiapepsin P11838 CARP_CRYPA Cryphonectria parasitica 3 0.7474
Endothiapepsin P11838 CARP_CRYPA Cryphonectria parasitica 3 0.7474
Protein-tyrosine kinase 2-beta Q14289 FAK2_HUMAN Homo sapiens 4 0.7473
Protein-tyrosine kinase 2-beta Q14289 FAK2_HUMAN Homo sapiens 4 0.7473
Tyrosine-protein kinase JAK2 O60674 JAK2_HUMAN Homo sapiens 3 0.7472
Tyrosine-protein kinase JAK2 O60674 JAK2_HUMAN Homo sapiens 3 0.7472
Basic phospholipase A2 VRV-PL-VIIIa P59071 PA2B8_DABRR Daboia russelii 3 0.7471
Basic phospholipase A2 VRV-PL-VIIIa P59071 PA2B8_DABRR Daboia russelii 3 0.7471
Gag-Pol polyprotein P03367 POL_HV1BR Human immunodeficiency virus type 1 group M subtype B 3 0.7470
Gag-Pol polyprotein P03367 POL_HV1BR Human immunodeficiency virus type 1 group M subtype B 3 0.7470
Riboflavin biosynthesis protein Q9WZW1 Q9WZW1_THEMA Thermotoga maritima 3 0.7469
Riboflavin biosynthesis protein Q9WZW1 Q9WZW1_THEMA Thermotoga maritima 3 0.7469
Carbonic anhydrase 2 P00918 CAH2_HUMAN Homo sapiens 2 0.7467
Carbonic anhydrase 2 P00918 CAH2_HUMAN Homo sapiens 2 0.7467
Kinesin-like protein KIF11 P52732 KIF11_HUMAN Homo sapiens 3 0.7463
Kinesin-like protein KIF11 P52732 KIF11_HUMAN Homo sapiens 3 0.7463
Glucan 1,3-beta-glucosidase P29717 EXG1_CANAL Candida albicans 3 0.7462
Glucan 1,3-beta-glucosidase P29717 EXG1_CANAL Candida albicans 3 0.7462
Casein kinase II subunit alpha P68400 CSK21_HUMAN Homo sapiens 2 0.7461
Casein kinase II subunit alpha P68400 CSK21_HUMAN Homo sapiens 2 0.7461
Endothiapepsin P11838 CARP_CRYPA Cryphonectria parasitica 3 0.7457
Endothiapepsin P11838 CARP_CRYPA Cryphonectria parasitica 3 0.7457
Ethylene receptor 1 P49333 ETR1_ARATH Arabidopsis thaliana 3 0.7453
Ethylene receptor 1 P49333 ETR1_ARATH Arabidopsis thaliana 3 0.7453
Cyclin-dependent kinase 2 P24941 CDK2_HUMAN Homo sapiens 3 0.7450
Penicillin V acylase P12256 PAC_LYSSH Lysinibacillus sphaericus 3 0.7450
Cyclin-dependent kinase 2 P24941 CDK2_HUMAN Homo sapiens 3 0.7450
Prothrombin P00734 THRB_HUMAN Homo sapiens 4 0.7450
Prothrombin P00734 THRB_HUMAN Homo sapiens 4 0.7450
Penicillin V acylase P12256 PAC_LYSSH Lysinibacillus sphaericus 3 0.7450
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A Q9Y233 PDE10_HUMAN Homo sapiens 2 0.7449
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A Q9Y233 PDE10_HUMAN Homo sapiens 2 0.7449
Interstitial collagenase P03956 MMP1_HUMAN Homo sapiens 3 0.7446
Interstitial collagenase P03956 MMP1_HUMAN Homo sapiens 3 0.7446
Methylmalonyl-CoA decarboxylase P52045 SCPB_ECOLI Escherichia coli 3 0.7446
Methylmalonyl-CoA decarboxylase P52045 SCPB_ECOLI Escherichia coli 3 0.7446
Quercetin 2,3-dioxygenase Q7SIC2 QDOI_ASPJA Aspergillus japonicus 3 0.7444
Quercetin 2,3-dioxygenase Q7SIC2 QDOI_ASPJA Aspergillus japonicus 3 0.7444
Pol polyprotein Q90K99 Q90K99_9HIV1 Human immunodeficiency virus 1 3 0.7441
Pol polyprotein Q90K99 Q90K99_9HIV1 Human immunodeficiency virus 1 3 0.7441
Alpha-ketoglutarate-dependent dioxygenase FTO Q9C0B1 FTO_HUMAN Homo sapiens 4 0.7440
Gag-Pol polyprotein P03367 POL_HV1BR Human immunodeficiency virus type 1 group M subtype B 3 0.7440
Alpha-ketoglutarate-dependent dioxygenase FTO Q9C0B1 FTO_HUMAN Homo sapiens 4 0.7440
Gag-Pol polyprotein P03367 POL_HV1BR Human immunodeficiency virus type 1 group M subtype B 3 0.7440
Protein kinase C iota type Q62074 KPCI_MOUSE Mus musculus 3 0.7439
Protein kinase C iota type Q62074 KPCI_MOUSE Mus musculus 3 0.7439
Cyclin-dependent kinase 2 P24941 CDK2_HUMAN Homo sapiens 4 0.7439
Cyclin-dependent kinase 2 P24941 CDK2_HUMAN Homo sapiens 4 0.7439
Annexin A5 P08758 ANXA5_HUMAN Homo sapiens 2 0.7438
Annexin A5 P08758 ANXA5_HUMAN Homo sapiens 2 0.7438
Queuine tRNA-ribosyltransferase P28720 TGT_ZYMMO Zymomonas mobilis subsp. mobilis 3 0.7438
Queuine tRNA-ribosyltransferase P28720 TGT_ZYMMO Zymomonas mobilis subsp. mobilis 3 0.7438
Aurora kinase A O14965 AURKA_HUMAN Homo sapiens 3 0.7437
Aurora kinase A O14965 AURKA_HUMAN Homo sapiens 3 0.7437
Cyclin-dependent kinase 2 P24941 CDK2_HUMAN Homo sapiens 3 0.7436
Cyclin-dependent kinase 2 P24941 CDK2_HUMAN Homo sapiens 3 0.7436
Peroxisome proliferator-activated receptor gamma P37231 PPARG_HUMAN Homo sapiens 2 0.7434
Peroxisome proliferator-activated receptor gamma P37231 PPARG_HUMAN Homo sapiens 2 0.7434
HTH-type transcriptional repressor PurR P0ACP7 PURR_ECOLI Escherichia coli 3 0.7433
HTH-type transcriptional repressor PurR P0ACP7 PURR_ECOLI Escherichia coli 3 0.7433
Chymotrypsinogen A P00766 CTRA_BOVIN Bos taurus 3 0.7432
Tyrosine-protein kinase JAK2 O60674 JAK2_HUMAN Homo sapiens 3 0.7432
Chymotrypsinogen A P00766 CTRA_BOVIN Bos taurus 3 0.7432
Tyrosine-protein kinase JAK2 O60674 JAK2_HUMAN Homo sapiens 3 0.7432
Agglutinin alpha chain P18674 LECA_MACPO Maclura pomifera 3 0.7426
Agglutinin alpha chain P18674 LECA_MACPO Maclura pomifera 3 0.7426
Peroxisome proliferator-activated receptor gamma P37231 PPARG_HUMAN Homo sapiens 2 0.7425
Peroxisome proliferator-activated receptor gamma P37231 PPARG_HUMAN Homo sapiens 2 0.7425
Protein mono-ADP-ribosyltransferase PARP14 Q460N5 PAR14_HUMAN Homo sapiens 3 0.7424
Protein mono-ADP-ribosyltransferase PARP14 Q460N5 PAR14_HUMAN Homo sapiens 3 0.7424
Aldo-keto reductase family 1 member D1 P51857 AK1D1_HUMAN Homo sapiens 2 0.7424
Aldo-keto reductase family 1 member D1 P51857 AK1D1_HUMAN Homo sapiens 2 0.7424
Cyclin-dependent kinase 2 P24941 CDK2_HUMAN Homo sapiens 3 0.7423
Cyclin-dependent kinase 2 P24941 CDK2_HUMAN Homo sapiens 3 0.7423
Tyrosine-protein kinase JAK2 O60674 JAK2_HUMAN Homo sapiens 3 0.7421
Beta-lactamase Q79MP6 Q79MP6_PSEAI Pseudomonas aeruginosa 2 0.7421
Tyrosine-protein kinase JAK2 O60674 JAK2_HUMAN Homo sapiens 3 0.7421
Beta-lactamase Q79MP6 Q79MP6_PSEAI Pseudomonas aeruginosa 2 0.7421
Prolyl endopeptidase P23687 PPCE_PIG Sus scrofa 3 0.7416
Prolyl endopeptidase P23687 PPCE_PIG Sus scrofa 3 0.7416
Nickel-binding periplasmic protein P33590 NIKA_ECOLI Escherichia coli 2 0.7413
Nickel-binding periplasmic protein P33590 NIKA_ECOLI Escherichia coli 2 0.7413
Gag-Pol polyprotein P03367 POL_HV1BR Human immunodeficiency virus type 1 group M subtype B 4 0.7411
Gag-Pol polyprotein P03367 POL_HV1BR Human immunodeficiency virus type 1 group M subtype B 4 0.7411
Cell division protein FtsZ P0A029 FTSZ_STAAM Staphylococcus aureus 3 0.7410
Cell division protein FtsZ P0A029 FTSZ_STAAM Staphylococcus aureus 3 0.7410
Glutathione S-transferase Q8ILQ7 GST_PLAFA Plasmodium falciparum 3 0.7409
Glutathione S-transferase Q8ILQ7 GST_PLAFA Plasmodium falciparum 3 0.7409
Gag-Pol polyprotein P03367 POL_HV1BR Human immunodeficiency virus type 1 group M subtype B 3 0.7407
Gag-Pol polyprotein P03367 POL_HV1BR Human immunodeficiency virus type 1 group M subtype B 3 0.7407
ALK tyrosine kinase receptor Q9UM73 ALK_HUMAN Homo sapiens 3 0.7406
ALK tyrosine kinase receptor Q9UM73 ALK_HUMAN Homo sapiens 3 0.7406
Glycogen synthase kinase-3 beta P49841 GSK3B_HUMAN Homo sapiens 3 0.7405
Glycogen synthase kinase-3 beta P49841 GSK3B_HUMAN Homo sapiens 3 0.7405
Prothrombin P00734 THRB_HUMAN Homo sapiens 3 0.7404
Prothrombin P00734 THRB_HUMAN Homo sapiens 3 0.7404
3-hydroxyanthranilate 3,4-dioxygenase Q1LCS4 3HAO_CUPMC Cupriavidus metallidurans 2 0.7397
3-hydroxyanthranilate 3,4-dioxygenase Q1LCS4 3HAO_CUPMC Cupriavidus metallidurans 2 0.7397
Beta-secretase 1 P56817 BACE1_HUMAN Homo sapiens 3 0.7391
Beta-secretase 1 P56817 BACE1_HUMAN Homo sapiens 3 0.7391
Beta-secretase 1 P56817 BACE1_HUMAN Homo sapiens 3 0.7391
Beta-secretase 1 P56817 BACE1_HUMAN Homo sapiens 3 0.7391
Phospholipase A2, major isoenzyme P00592 PA21B_PIG Sus scrofa 2 0.7390
Phospholipase A2, major isoenzyme P00592 PA21B_PIG Sus scrofa 2 0.7390
Genome polyprotein P26663 POLG_HCVBK Hepatitis C virus genotype 1b 3 0.7389
Genome polyprotein P26663 POLG_HCVBK Hepatitis C virus genotype 1b 3 0.7389
Nitric oxide synthase, inducible P29477 NOS2_MOUSE Mus musculus 3 0.7386
Nitric oxide synthase, inducible P29477 NOS2_MOUSE Mus musculus 3 0.7386
Serine/threonine-protein kinase Chk1 O14757 CHK1_HUMAN Homo sapiens 3 0.7384
Serine/threonine-protein kinase Chk1 O14757 CHK1_HUMAN Homo sapiens 3 0.7384
Kinesin-like protein KIF11 P52732 KIF11_HUMAN Homo sapiens 3 0.7383
High affinity nerve growth factor receptor P04629 NTRK1_HUMAN Homo sapiens 3 0.7383
High affinity nerve growth factor receptor P04629 NTRK1_HUMAN Homo sapiens 3 0.7383
Kinesin-like protein KIF11 P52732 KIF11_HUMAN Homo sapiens 3 0.7383
Disintegrin and metalloproteinase domain-containing protein 17 P78536 ADA17_HUMAN Homo sapiens 2 0.7382
Disintegrin and metalloproteinase domain-containing protein 17 P78536 ADA17_HUMAN Homo sapiens 2 0.7382
Mitogen-activated protein kinase 1 P28482 MK01_HUMAN Homo sapiens 3 0.7381
Mitogen-activated protein kinase 1 P28482 MK01_HUMAN Homo sapiens 3 0.7381
CCA-adding enzyme O28126 CCA_ARCFU Archaeoglobus fulgidus 3 0.7378
CCA-adding enzyme O28126 CCA_ARCFU Archaeoglobus fulgidus 3 0.7378
Lactoylglutathione lyase Q9CPU0 LGUL_MOUSE Mus musculus 2 0.7376
Lactoylglutathione lyase Q9CPU0 LGUL_MOUSE Mus musculus 2 0.7376
Mitochondrial poly(A) polymerase F1NBW0 F1NBW0_CHICK Gallus gallus 2 0.7373
Mitochondrial poly(A) polymerase F1NBW0 F1NBW0_CHICK Gallus gallus 2 0.7373
Virulence sensor histidine kinase PhoQ P0DM80 PHOQ_SALTY Salmonella typhimurium 3 0.7372
Virulence sensor histidine kinase PhoQ P0DM80 PHOQ_SALTY Salmonella typhimurium 3 0.7372
Ribosyldihydronicotinamide dehydrogenase [quinone] P16083 NQO2_HUMAN Homo sapiens 3 0.7371
Ribosyldihydronicotinamide dehydrogenase [quinone] P16083 NQO2_HUMAN Homo sapiens 3 0.7371
Cell division protein FtsZ P0A031 FTSZ_STAAU Staphylococcus aureus 3 0.7371
Sepiapterin reductase Q64105 SPRE_MOUSE Mus musculus 3 0.7371
Cell division protein FtsZ P0A031 FTSZ_STAAU Staphylococcus aureus 3 0.7371
Sepiapterin reductase Q64105 SPRE_MOUSE Mus musculus 3 0.7371
Carbonic anhydrase 2 P00918 CAH2_HUMAN Homo sapiens 2 0.7368
Carbonic anhydrase 2 P00918 CAH2_HUMAN Homo sapiens 2 0.7368
HTH-type transcriptional repressor PurR P0ACP7 PURR_ECOLI Escherichia coli 3 0.7367
HTH-type transcriptional repressor PurR P0ACP7 PURR_ECOLI Escherichia coli 3 0.7367
Proto-oncogene tyrosine-protein kinase Src P00523 SRC_CHICK Gallus gallus 2 0.7364
Proto-oncogene tyrosine-protein kinase Src P00523 SRC_CHICK Gallus gallus 2 0.7364
Chaperone protein ClpB Q9RA63 CLPB_THET8 Thermus thermophilus 3 0.7362
Chaperone protein ClpB Q9RA63 CLPB_THET8 Thermus thermophilus 3 0.7362
Genome polyprotein O92972 POLG_HCVJ4 Hepatitis C virus genotype 1b 2 0.7361
Genome polyprotein O92972 POLG_HCVJ4 Hepatitis C virus genotype 1b 2 0.7361
Cyclin-dependent kinase 9 P50750 CDK9_HUMAN Homo sapiens 3 0.7357
Cyclin-dependent kinase 9 P50750 CDK9_HUMAN Homo sapiens 3 0.7357
Formate--tetrahydrofolate ligase Q2RM91 FTHS_MOOTA Moorella thermoacetica 2 0.7354
Formate--tetrahydrofolate ligase Q2RM91 FTHS_MOOTA Moorella thermoacetica 2 0.7354
Transitional endoplasmic reticulum ATPase P55072 TERA_HUMAN Homo sapiens 3 0.7353
Adenosine monophosphate-protein transferase Q8ZVF7 Q8ZVF7_PYRAE Pyrobaculum aerophilum 3 0.7353
Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial Q8N5Z0 AADAT_HUMAN Homo sapiens 2 0.7353
Transitional endoplasmic reticulum ATPase P55072 TERA_HUMAN Homo sapiens 3 0.7353
Adenosine monophosphate-protein transferase Q8ZVF7 Q8ZVF7_PYRAE Pyrobaculum aerophilum 3 0.7353
Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial Q8N5Z0 AADAT_HUMAN Homo sapiens 2 0.7353
Phospholipase A2, major isoenzyme P00592 PA21B_PIG Sus scrofa 3 0.7352
Phospholipase A2, major isoenzyme P00592 PA21B_PIG Sus scrofa 3 0.7352
Serine/threonine-protein kinase pim-1 P11309 PIM1_HUMAN Homo sapiens 3 0.7351
Serine/threonine-protein kinase pim-1 P11309 PIM1_HUMAN Homo sapiens 3 0.7351
Clathrin heavy chain 1 Q00610 CLH1_HUMAN Homo sapiens 3 0.7346
Clathrin heavy chain 1 Q00610 CLH1_HUMAN Homo sapiens 3 0.7346
Queuine tRNA-ribosyltransferase P28720 TGT_ZYMMO Zymomonas mobilis subsp. mobilis 3 0.7345
Queuine tRNA-ribosyltransferase P28720 TGT_ZYMMO Zymomonas mobilis subsp. mobilis 3 0.7345
Carbonic anhydrase 2 P00918 CAH2_HUMAN Homo sapiens 2 0.7341
Carbonic anhydrase 2 P00918 CAH2_HUMAN Homo sapiens 2 0.7341
Gag-Pol polyprotein P03366 POL_HV1B1 Human immunodeficiency virus type 1 group M subtype B 3 0.7337
Gag-Pol polyprotein P03366 POL_HV1B1 Human immunodeficiency virus type 1 group M subtype B 3 0.7337
Myosin heavy chain, striated muscle P24733 MYS_ARGIR Argopecten irradians 3 0.7332
Myosin heavy chain, striated muscle P24733 MYS_ARGIR Argopecten irradians 3 0.7332
Mitogen-activated protein kinase 1 P63086 MK01_RAT Rattus norvegicus 3 0.7331
Mitogen-activated protein kinase 1 P63086 MK01_RAT Rattus norvegicus 3 0.7331
Abscisic acid receptor PYL2 O80992 PYL2_ARATH Arabidopsis thaliana 3 0.7330
Abscisic acid receptor PYL2 O80992 PYL2_ARATH Arabidopsis thaliana 3 0.7330
Cyclin-dependent kinase 2 P24941 CDK2_HUMAN Homo sapiens 3 0.7328
Cyclin-dependent kinase 2 P24941 CDK2_HUMAN Homo sapiens 3 0.7328
Bifunctional epoxide hydrolase 2 P34913 HYES_HUMAN Homo sapiens 2 0.7325
Cyclin-dependent kinase 2 P24941 CDK2_HUMAN Homo sapiens 3 0.7325
Bifunctional epoxide hydrolase 2 P34913 HYES_HUMAN Homo sapiens 2 0.7325
Cyclin-dependent kinase 2 P24941 CDK2_HUMAN Homo sapiens 3 0.7325
Benzoylformate decarboxylase P20906 MDLC_PSEPU Pseudomonas putida 3 0.7321
Benzoylformate decarboxylase P20906 MDLC_PSEPU Pseudomonas putida 3 0.7321
Nitric oxide synthase, inducible P29477 NOS2_MOUSE Mus musculus 2 0.7320
Purine nucleoside phosphorylase DeoD-type Q5EEL8 DEOD_BACCE Bacillus cereus 3 0.7320
Nitric oxide synthase, inducible P29477 NOS2_MOUSE Mus musculus 2 0.7320
Purine nucleoside phosphorylase DeoD-type Q5EEL8 DEOD_BACCE Bacillus cereus 3 0.7320
2-phospho-L-lactate transferase Q8PVT6 COFD_METMA Methanosarcina mazei 2 0.7319
2-phospho-L-lactate transferase Q8PVT6 COFD_METMA Methanosarcina mazei 2 0.7319
Formylmethanofuran--tetrahydromethanopterin formyltransferase Q49610 FTR_METKA Methanopyrus kandleri 3 0.7318
Formylmethanofuran--tetrahydromethanopterin formyltransferase Q49610 FTR_METKA Methanopyrus kandleri 3 0.7318
Prothrombin P00734 THRB_HUMAN Homo sapiens 3 0.7315
Prothrombin P00734 THRB_HUMAN Homo sapiens 3 0.7315
Endoplasmin P41148 ENPL_CANLF Canis lupus familiaris 3 0.7313
Serine hydroxymethyltransferase Q7SIB6 Q7SIB6_GEOSE Geobacillus stearothermophilus 3 0.7313
Serine hydroxymethyltransferase Q7SIB6 Q7SIB6_GEOSE Geobacillus stearothermophilus 3 0.7313
Endoplasmin P41148 ENPL_CANLF Canis lupus familiaris 3 0.7313
Prothrombin P00734 THRB_HUMAN Homo sapiens 3 0.7310
Prothrombin P00734 THRB_HUMAN Homo sapiens 3 0.7310
3',5'-cyclic-AMP phosphodiesterase 4D Q08499 PDE4D_HUMAN Homo sapiens 3 0.7308
3',5'-cyclic-AMP phosphodiesterase 4D Q08499 PDE4D_HUMAN Homo sapiens 3 0.7308
Basic phospholipase A2 VRV-PL-VIIIa P59071 PA2B8_DABRR Daboia russelii 2 0.7306
Fructose-1,6-bisphosphatase 1 P09467 F16P1_HUMAN Homo sapiens 3 0.7306
Basic phospholipase A2 VRV-PL-VIIIa P59071 PA2B8_DABRR Daboia russelii 2 0.7306
Fructose-1,6-bisphosphatase 1 P09467 F16P1_HUMAN Homo sapiens 3 0.7306
Fructose-1,6-bisphosphatase 1 P09467 F16P1_HUMAN Homo sapiens 3 0.7303
Serine/threonine-protein kinase Chk1 O14757 CHK1_HUMAN Homo sapiens 3 0.7303
Fructose-1,6-bisphosphatase 1 P09467 F16P1_HUMAN Homo sapiens 3 0.7303
Serine/threonine-protein kinase Chk1 O14757 CHK1_HUMAN Homo sapiens 3 0.7303
3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase P19992 HSD_STREX Streptomyces exfoliatus 2 0.7299
3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase P19992 HSD_STREX Streptomyces exfoliatus 2 0.7299
Prothrombin P00734 THRB_HUMAN Homo sapiens 3 0.7299
Prothrombin P00734 THRB_HUMAN Homo sapiens 3 0.7299
Transcriptional activator, LuxR/UhpA family of regulators Q7NQP7 Q7NQP7_CHRVO Chromobacterium violaceum 3 0.7298
Heat shock protein HSP 90-alpha P07900 HS90A_HUMAN Homo sapiens 2 0.7298
Transcriptional activator, LuxR/UhpA family of regulators Q7NQP7 Q7NQP7_CHRVO Chromobacterium violaceum 3 0.7298
Heat shock protein HSP 90-alpha P07900 HS90A_HUMAN Homo sapiens 2 0.7298
Casein kinase II subunit alpha P68400 CSK21_HUMAN Homo sapiens 2 0.7297
Casein kinase II subunit alpha P68400 CSK21_HUMAN Homo sapiens 2 0.7297
Gag-Pol polyprotein P03366 POL_HV1B1 Human immunodeficiency virus type 1 group M subtype B 3 0.7293
Gag-Pol polyprotein P03366 POL_HV1B1 Human immunodeficiency virus type 1 group M subtype B 3 0.7293
Cyclin-dependent kinase 8 P49336 CDK8_HUMAN Homo sapiens 3 0.7292
Cyclin-dependent kinase 8 P49336 CDK8_HUMAN Homo sapiens 3 0.7292
Mitogen-activated protein kinase 14 Q16539 MK14_HUMAN Homo sapiens 3 0.7290
Mitogen-activated protein kinase 14 Q16539 MK14_HUMAN Homo sapiens 3 0.7290
Gag-Pol polyprotein P0C6F2 POL_HV1LW Human immunodeficiency virus type 1 group M subtype B 3 0.7288
Gag-Pol polyprotein P0C6F2 POL_HV1LW Human immunodeficiency virus type 1 group M subtype B 3 0.7288
Glycogen synthase kinase-3 beta P49841 GSK3B_HUMAN Homo sapiens 3 0.7287
Poly [ADP-ribose] polymerase 1 P09874 PARP1_HUMAN Homo sapiens 3 0.7287
Poly [ADP-ribose] polymerase 1 P09874 PARP1_HUMAN Homo sapiens 3 0.7287
Glycogen synthase kinase-3 beta P49841 GSK3B_HUMAN Homo sapiens 3 0.7287
Carbonic anhydrase 4 Q64444 CAH4_MOUSE Mus musculus 2 0.7285
UDP-N-acetylenolpyruvoylglucosamine reductase P08373 MURB_ECOLI Escherichia coli 3 0.7285
Carbonic anhydrase 4 Q64444 CAH4_MOUSE Mus musculus 2 0.7285
UDP-N-acetylenolpyruvoylglucosamine reductase P08373 MURB_ECOLI Escherichia coli 3 0.7285
Phenylalanine-4-hydroxylase P00439 PH4H_HUMAN Homo sapiens 2 0.7279
Phenylalanine-4-hydroxylase P00439 PH4H_HUMAN Homo sapiens 2 0.7279
Tetracycline repressor protein class D P0ACT4 TETR4_ECOLX Escherichia coli 3 0.7277
Endoplasmin P41148 ENPL_CANLF Canis lupus familiaris 3 0.7277
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase Q8ZMF7 ISPF_SALTY Salmonella typhimurium 3 0.7277
Tetracycline repressor protein class D P0ACT4 TETR4_ECOLX Escherichia coli 3 0.7277
Endoplasmin P41148 ENPL_CANLF Canis lupus familiaris 3 0.7277
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase Q8ZMF7 ISPF_SALTY Salmonella typhimurium 3 0.7277
Oxygenase Q194P4 Q194P4_STRAA Streptomyces argillaceus 3 0.7275
Oxygenase Q194P4 Q194P4_STRAA Streptomyces argillaceus 3 0.7275
Tyrosine-protein kinase HCK P08631 HCK_HUMAN Homo sapiens 3 0.7275
Tyrosine-protein kinase HCK P08631 HCK_HUMAN Homo sapiens 3 0.7275
Orf1a polyprotein Q692E5 Q692E5_CVHSA SARS coronavirus TJF 2 0.7272
Orf1a polyprotein Q692E5 Q692E5_CVHSA SARS coronavirus TJF 2 0.7272
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform P48736 PK3CG_HUMAN Homo sapiens 3 0.7271
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform P48736 PK3CG_HUMAN Homo sapiens 3 0.7271
Mitogen-activated protein kinase 8 P45983 MK08_HUMAN Homo sapiens 3 0.7270
Mitogen-activated protein kinase 8 P45983 MK08_HUMAN Homo sapiens 3 0.7270
Subunit alpha of sarocosine oxidase Q50LF0 Q50LF0_9CORY Corynebacterium sp. U-96 3 0.7267
Subunit alpha of sarocosine oxidase Q50LF0 Q50LF0_9CORY Corynebacterium sp. U-96 3 0.7267
Queuine tRNA-ribosyltransferase P28720 TGT_ZYMMO Zymomonas mobilis subsp. mobilis 3 0.7266
Queuine tRNA-ribosyltransferase P28720 TGT_ZYMMO Zymomonas mobilis subsp. mobilis 3 0.7266
Gag-Pol polyprotein P03367 POL_HV1BR Human immunodeficiency virus type 1 group M subtype B 3 0.7264
Gag-Pol polyprotein P03367 POL_HV1BR Human immunodeficiency virus type 1 group M subtype B 3 0.7264
Queuine tRNA-ribosyltransferase P28720 TGT_ZYMMO Zymomonas mobilis subsp. mobilis 3 0.7262
Queuine tRNA-ribosyltransferase P28720 TGT_ZYMMO Zymomonas mobilis subsp. mobilis 3 0.7262
Acyl-CoA:acyl-CoA alkyltransferase Q8PDX2 OLEA_XANCP Xanthomonas campestris pv. campestris 3 0.7260
Acyl-CoA:acyl-CoA alkyltransferase Q8PDX2 OLEA_XANCP Xanthomonas campestris pv. campestris 3 0.7260
Cyclin-dependent kinase 2 P24941 CDK2_HUMAN Homo sapiens 3 0.7258
Cyclin-dependent kinase 2 P24941 CDK2_HUMAN Homo sapiens 3 0.7258
Fibroblast growth factor receptor 1 P11362 FGFR1_HUMAN Homo sapiens 2 0.7257
Fibroblast growth factor receptor 1 P11362 FGFR1_HUMAN Homo sapiens 2 0.7257
Gag-Pol polyprotein P12497 POL_HV1N5 Human immunodeficiency virus type 1 group M subtype B 3 0.7255
Gag-Pol polyprotein P12497 POL_HV1N5 Human immunodeficiency virus type 1 group M subtype B 3 0.7255
Avidin P02701 AVID_CHICK Gallus gallus 2 0.7253
Avidin P02701 AVID_CHICK Gallus gallus 2 0.7253
Peptidyl-prolyl cis-trans isomerase FKBP1A P62942 FKB1A_HUMAN Homo sapiens 2 0.7253
Peptidyl-prolyl cis-trans isomerase FKBP1A P62942 FKB1A_HUMAN Homo sapiens 2 0.7253
Putative protease I Q8A8A4 Q8A8A4_BACTN Bacteroides thetaiotaomicron 3 0.7252
Lactoperoxidase A0A452E9Y6 PERL_CAPHI Capra hircus 2 0.7252
Lactoperoxidase A0A452E9Y6 PERL_CAPHI Capra hircus 2 0.7252
Putative protease I Q8A8A4 Q8A8A4_BACTN Bacteroides thetaiotaomicron 3 0.7252
2',3'-cyclic-nucleotide 3'-phosphodiesterase P16330 CN37_MOUSE Mus musculus 2 0.7250
Cyclin-dependent kinase 9 P50750 CDK9_HUMAN Homo sapiens 3 0.7250
Cyclin-dependent kinase 9 P50750 CDK9_HUMAN Homo sapiens 3 0.7250
2',3'-cyclic-nucleotide 3'-phosphodiesterase P16330 CN37_MOUSE Mus musculus 2 0.7250
Glucose-1-phosphate thymidylyltransferase Q9HU22 Q9HU22_PSEAE Pseudomonas aeruginosa 3 0.7249
Nickel-binding periplasmic protein P33590 NIKA_ECOLI Escherichia coli 2 0.7249
Nickel-binding periplasmic protein P33590 NIKA_ECOLI Escherichia coli 2 0.7249
Glucose-1-phosphate thymidylyltransferase Q9HU22 Q9HU22_PSEAE Pseudomonas aeruginosa 3 0.7249
CCA-adding enzyme O28126 CCA_ARCFU Archaeoglobus fulgidus 2 0.7246
CCA-adding enzyme O28126 CCA_ARCFU Archaeoglobus fulgidus 2 0.7246
histidine kinase Q9WZV7 Q9WZV7_THEMA Thermotoga maritima 3 0.7240
5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase Q81LL4 MTNN_BACAN Bacillus anthracis 2 0.7240
5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase Q81LL4 MTNN_BACAN Bacillus anthracis 2 0.7240
Alpha-ketoglutarate-dependent dioxygenase FTO Q9C0B1 FTO_HUMAN Homo sapiens 2 0.7240
histidine kinase Q9WZV7 Q9WZV7_THEMA Thermotoga maritima 3 0.7240
Alpha-ketoglutarate-dependent dioxygenase FTO Q9C0B1 FTO_HUMAN Homo sapiens 2 0.7240
Putative snRNP Sm-like protein Q8ZYG5 Q8ZYG5_PYRAE Pyrobaculum aerophilum 2 0.7239
Putative snRNP Sm-like protein Q8ZYG5 Q8ZYG5_PYRAE Pyrobaculum aerophilum 2 0.7239
ALK tyrosine kinase receptor Q9UM73 ALK_HUMAN Homo sapiens 3 0.7237
ALK tyrosine kinase receptor Q9UM73 ALK_HUMAN Homo sapiens 3 0.7237
Pyridoxal kinase O00764 PDXK_HUMAN Homo sapiens 2 0.7236
Pyridoxal kinase O00764 PDXK_HUMAN Homo sapiens 2 0.7236
Mitogen-activated protein kinase 14 Q16539 MK14_HUMAN Homo sapiens 3 0.7235
Mitogen-activated protein kinase 14 Q16539 MK14_HUMAN Homo sapiens 3 0.7235
UDP-3-O-acyl-N-acetylglucosamine deacetylase O67648 LPXC_AQUAE Aquifex aeolicus 2 0.7234
UDP-3-O-acyl-N-acetylglucosamine deacetylase O67648 LPXC_AQUAE Aquifex aeolicus 2 0.7234
Mitogen-activated protein kinase 14 Q16539 MK14_HUMAN Homo sapiens 3 0.7234
Mitogen-activated protein kinase 14 Q16539 MK14_HUMAN Homo sapiens 3 0.7234
Albumin P02768 ALBU_HUMAN Homo sapiens 2 0.7233
Albumin P02768 ALBU_HUMAN Homo sapiens 2 0.7233
Bifunctional dihydrofolate reductase-thymidylate synthase O02604 DRTS_PLAVI Plasmodium vivax 3 0.7231
Bifunctional dihydrofolate reductase-thymidylate synthase O02604 DRTS_PLAVI Plasmodium vivax 3 0.7231
Dipeptidyl peptidase 4 P27487 DPP4_HUMAN Homo sapiens 3 0.7230
Dipeptidyl peptidase 4 P27487 DPP4_HUMAN Homo sapiens 3 0.7230
Abscisic acid receptor PYL1 Q8VZS8 PYL1_ARATH Arabidopsis thaliana 3 0.7229
Abscisic acid receptor PYL1 Q8VZS8 PYL1_ARATH Arabidopsis thaliana 3 0.7229
Phosphodiesterase Q8WQX9 Q8WQX9_9TRYP Trypanosoma brucei 3 0.7228
Phosphodiesterase Q8WQX9 Q8WQX9_9TRYP Trypanosoma brucei 3 0.7228
tRNA(Phe) (4-demethylwyosine(37)-C(7)) aminocarboxypropyltransferase O58523 TYW2_PYRHO Pyrococcus horikoshii 3 0.7228
tRNA(Phe) (4-demethylwyosine(37)-C(7)) aminocarboxypropyltransferase O58523 TYW2_PYRHO Pyrococcus horikoshii 3 0.7228
Prothrombin P00734 THRB_HUMAN Homo sapiens 2 0.7224
Thymidylate synthase Q9Y052 Q9Y052_CAEEL Caenorhabditis elegans 3 0.7224
Prothrombin P00734 THRB_HUMAN Homo sapiens 2 0.7224
Thymidylate synthase Q9Y052 Q9Y052_CAEEL Caenorhabditis elegans 3 0.7224
Beta-1 adrenergic receptor P07700 ADRB1_MELGA Meleagris gallopavo 2 0.7222
Beta-1 adrenergic receptor P07700 ADRB1_MELGA Meleagris gallopavo 2 0.7222
Gag-Pol polyprotein P12497 POL_HV1N5 Human immunodeficiency virus type 1 group M subtype B 2 0.7221
L-lactate dehydrogenase A chain P13491 LDHA_RABIT Oryctolagus cuniculus 2 0.7221
Lethal factor P15917 LEF_BACAN Bacillus anthracis 3 0.7221
L-lactate dehydrogenase A chain P13491 LDHA_RABIT Oryctolagus cuniculus 2 0.7221
Lethal factor P15917 LEF_BACAN Bacillus anthracis 3 0.7221
Gag-Pol polyprotein P12497 POL_HV1N5 Human immunodeficiency virus type 1 group M subtype B 2 0.7221
HTH-type transcriptional repressor PurR P0ACP7 PURR_ECOLI Escherichia coli 2 0.7220
HTH-type transcriptional repressor PurR P0ACP7 PURR_ECOLI Escherichia coli 2 0.7220
Cyclin-dependent kinase 2 P24941 CDK2_HUMAN Homo sapiens 4 0.7216
Cyclin-dependent kinase 2 P24941 CDK2_HUMAN Homo sapiens 4 0.7216
Caffeoyl-CoA O-methyltransferase Q40313 CAMT_MEDSA Medicago sativa 3 0.7214
Caffeoyl-CoA O-methyltransferase Q40313 CAMT_MEDSA Medicago sativa 3 0.7214
Prothrombin P00734 THRB_HUMAN Homo sapiens 3 0.7213
Prothrombin P00734 THRB_HUMAN Homo sapiens 3 0.7213
cAMP-dependent protein kinase catalytic subunit alpha P05132 KAPCA_MOUSE Mus musculus 4 0.7213
cAMP-dependent protein kinase catalytic subunit alpha P05132 KAPCA_MOUSE Mus musculus 4 0.7213
S-adenosylmethionine decarboxylase proenzyme P17707 DCAM_HUMAN Homo sapiens 3 0.7212
S-adenosylmethionine decarboxylase proenzyme P17707 DCAM_HUMAN Homo sapiens 3 0.7212
Genome polyprotein P26663 POLG_HCVBK Hepatitis C virus genotype 1b 2 0.7211
Genome polyprotein P26663 POLG_HCVBK Hepatitis C virus genotype 1b 2 0.7211
Cystathionine beta-lyase MetC P06721 METC_ECOLI Escherichia coli 3 0.7211
Cystathionine beta-lyase MetC P06721 METC_ECOLI Escherichia coli 3 0.7211
Cyclin-dependent kinase 2 P24941 CDK2_HUMAN Homo sapiens 3 0.7210
Cyclin-dependent kinase 2 P24941 CDK2_HUMAN Homo sapiens 3 0.7210
Carbonic anhydrase 2 P00918 CAH2_HUMAN Homo sapiens 2 0.7209
Carbonic anhydrase 2 P00918 CAH2_HUMAN Homo sapiens 2 0.7209
UDP-galactopyranose mutase Q48485 GLF1_KLEPN Klebsiella pneumoniae 3 0.7207
UDP-galactopyranose mutase Q48485 GLF1_KLEPN Klebsiella pneumoniae 3 0.7207
Serine/threonine-protein kinase Chk2 O96017 CHK2_HUMAN Homo sapiens 2 0.7206
Serine/threonine-protein kinase Chk2 O96017 CHK2_HUMAN Homo sapiens 2 0.7206
Prenyltransferase Q4R2T2 Q4R2T2_STRC1 Streptomyces sp 3 0.7205
Prenyltransferase Q4R2T2 Q4R2T2_STRC1 Streptomyces sp 3 0.7205
D-alanyl-D-alanine carboxypeptidase P15555 DAC_STRSR Streptomyces sp 2 0.7203
2-aminohexano-6-lactam racemase Q7M181 ACLR_ACHOB Achromobacter obae 2 0.7203
Single-stranded-DNA-specific exonuclease RecJ D0EM60 D0EM60_DEIRD Deinococcus radiodurans 2 0.7203
D-alanyl-D-alanine carboxypeptidase P15555 DAC_STRSR Streptomyces sp 2 0.7203
2-aminohexano-6-lactam racemase Q7M181 ACLR_ACHOB Achromobacter obae 2 0.7203
Single-stranded-DNA-specific exonuclease RecJ D0EM60 D0EM60_DEIRD Deinococcus radiodurans 2 0.7203
Hexokinase-4 P35557 HXK4_HUMAN Homo sapiens 3 0.7202
Hexokinase-4 P35557 HXK4_HUMAN Homo sapiens 3 0.7202
Methylketone synthase I E0YCS2 E0YCS2_SOLHA Solanum habrochaites 2 0.7201
Methylketone synthase I E0YCS2 E0YCS2_SOLHA Solanum habrochaites 2 0.7201
Carbonic anhydrase 2 P00918 CAH2_HUMAN Homo sapiens 2 0.7200
Carbonic anhydrase 2 P00918 CAH2_HUMAN Homo sapiens 2 0.7200
Plasma membrane ATPase Q42932 Q42932_NICPL Nicotiana plumbaginifolia 2 0.7199
Plasma membrane ATPase Q42932 Q42932_NICPL Nicotiana plumbaginifolia 2 0.7199
NAD(P)H-hydrate epimerase Q8K4Z3 NNRE_MOUSE Mus musculus 3 0.7197
NAD(P)H-hydrate epimerase Q8K4Z3 NNRE_MOUSE Mus musculus 3 0.7197
Serine/threonine-protein kinase Chk2 O96017 CHK2_HUMAN Homo sapiens 3 0.7193
Serine/threonine-protein kinase Chk2 O96017 CHK2_HUMAN Homo sapiens 3 0.7193
L-lactate dehydrogenase A chain P04642 LDHA_RAT Rattus norvegicus 2 0.7191
Thymidylate synthase P00469 TYSY_LACCA Lacticaseibacillus casei 2 0.7191
L-lactate dehydrogenase A chain P04642 LDHA_RAT Rattus norvegicus 2 0.7191
Thymidylate synthase P00469 TYSY_LACCA Lacticaseibacillus casei 2 0.7191
cAMP-dependent protein kinase type I-alpha regulatory subunit P00514 KAP0_BOVIN Bos taurus 2 0.7190
cAMP-dependent protein kinase type I-alpha regulatory subunit P00514 KAP0_BOVIN Bos taurus 2 0.7190
Pentaerythritol tetranitrate reductase P71278 P71278_ENTCL Enterobacter cloacae 2 0.7189
Pentaerythritol tetranitrate reductase P71278 P71278_ENTCL Enterobacter cloacae 2 0.7189
Urokinase-type plasminogen activator P00749 UROK_HUMAN Homo sapiens 3 0.7187
Urokinase-type plasminogen activator P00749 UROK_HUMAN Homo sapiens 3 0.7187
Phosphoglycerate kinase Q83AU6 PGK_COXBU Coxiella burnetii 3 0.7186
Phosphoglycerate kinase Q83AU6 PGK_COXBU Coxiella burnetii 3 0.7186
tyrosine--tRNA ligase Q4QFJ7 Q4QFJ7_LEIMA Leishmania major 3 0.7185
tyrosine--tRNA ligase Q4QFJ7 Q4QFJ7_LEIMA Leishmania major 3 0.7185
Type IV / VI secretion system DotU domain-containing protein Q9KN50 Q9KN50_VIBCH Vibrio cholerae serotype O1 2 0.7180
Serine/threonine-protein kinase pim-1 P11309 PIM1_HUMAN Homo sapiens 4 0.7180
Serine/threonine-protein kinase pim-1 P11309 PIM1_HUMAN Homo sapiens 4 0.7180
Type IV / VI secretion system DotU domain-containing protein Q9KN50 Q9KN50_VIBCH Vibrio cholerae serotype O1 2 0.7180
Serine/threonine-protein kinase Chk1 O14757 CHK1_HUMAN Homo sapiens 4 0.7178
Serine/threonine-protein kinase Chk1 O14757 CHK1_HUMAN Homo sapiens 4 0.7178
FMN-dependent NAD(P)H:quinone oxidoreductase 1 Q9I5F3 AZOR1_PSEAE Pseudomonas aeruginosa 2 0.7176
FMN-dependent NAD(P)H:quinone oxidoreductase 1 Q9I5F3 AZOR1_PSEAE Pseudomonas aeruginosa 2 0.7176
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 Q9Y3Q4 HCN4_HUMAN Homo sapiens 3 0.7174
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 Q9Y3Q4 HCN4_HUMAN Homo sapiens 3 0.7174
HTH-type transcriptional repressor PurR P0ACP7 PURR_ECOLI Escherichia coli 2 0.7173
5-methylthioadenosine/S-adenosylhomocysteine deaminase Q7NZ90 Q7NZ90_CHRVO Chromobacterium violaceum 2 0.7173
HTH-type transcriptional repressor PurR P0ACP7 PURR_ECOLI Escherichia coli 2 0.7173
5-methylthioadenosine/S-adenosylhomocysteine deaminase Q7NZ90 Q7NZ90_CHRVO Chromobacterium violaceum 2 0.7173
L-lactate dehydrogenase (cytochrome) P00175 CYB2_YEAST Saccharomyces cerevisiae 2 0.7169
L-lactate dehydrogenase (cytochrome) P00175 CYB2_YEAST Saccharomyces cerevisiae 2 0.7169
adenine phosphoribosyltransferase Q967M2 Q967M2_GIAIN Giardia intestinalis 2 0.7168
ATP-dependent molecular chaperone HSP82 P02829 HSP82_YEAST Saccharomyces cerevisiae 3 0.7168
DNA-binding transcriptional dual regulator CRP P0ACJ8 CRP_ECOLI Escherichia coli 3 0.7168
adenine phosphoribosyltransferase Q967M2 Q967M2_GIAIN Giardia intestinalis 2 0.7168
ATP-dependent molecular chaperone HSP82 P02829 HSP82_YEAST Saccharomyces cerevisiae 3 0.7168
DNA-binding transcriptional dual regulator CRP P0ACJ8 CRP_ECOLI Escherichia coli 3 0.7168
Serine/threonine-protein kinase pim-1 P11309 PIM1_HUMAN Homo sapiens 3 0.7167
Serine/threonine-protein kinase pim-1 P11309 PIM1_HUMAN Homo sapiens 3 0.7167
N-terminal acetyltransferase A complex subunit NAT1 P12945 NAT1_YEAST Saccharomyces cerevisiae 2 0.7159
[LysW]-aminoadipate kinase O50147 LYSZ_THET2 Thermus thermophilus 3 0.7159
N-terminal acetyltransferase A complex subunit NAT1 P12945 NAT1_YEAST Saccharomyces cerevisiae 2 0.7159
[LysW]-aminoadipate kinase O50147 LYSZ_THET2 Thermus thermophilus 3 0.7159
Uracil phosphoribosyltransferase Q26998 UPP_TOXGO Toxoplasma gondii 3 0.7158
Nitric oxide synthase, inducible P29477 NOS2_MOUSE Mus musculus 2 0.7158
Uracil phosphoribosyltransferase Q26998 UPP_TOXGO Toxoplasma gondii 3 0.7158
Prothrombin P00734 THRB_HUMAN Homo sapiens 3 0.7158
Nitric oxide synthase, inducible P29477 NOS2_MOUSE Mus musculus 2 0.7158
Prothrombin P00734 THRB_HUMAN Homo sapiens 3 0.7158
Disintegrin and metalloproteinase domain-containing protein 17 P78536 ADA17_HUMAN Homo sapiens 4 0.7157
Disintegrin and metalloproteinase domain-containing protein 17 P78536 ADA17_HUMAN Homo sapiens 4 0.7157
Hepatocyte growth factor receptor P08581 MET_HUMAN Homo sapiens 4 0.7156
Hepatocyte growth factor receptor P08581 MET_HUMAN Homo sapiens 4 0.7156
cGMP-dependent protein kinase 1 Q13976 KGP1_HUMAN Homo sapiens 3 0.7153
cGMP-dependent protein kinase 1 Q13976 KGP1_HUMAN Homo sapiens 3 0.7153
Prothrombin P00734 THRB_HUMAN Homo sapiens 3 0.7152
Prothrombin P00734 THRB_HUMAN Homo sapiens 3 0.7152
Inosine-5'-monophosphate dehydrogenase P50097 IMDH_TRIFO Tritrichomonas foetus 2 0.7151
Guanylate kinase P15454 KGUA_YEAST Saccharomyces cerevisiae 3 0.7151
Inosine-5'-monophosphate dehydrogenase P50097 IMDH_TRIFO Tritrichomonas foetus 2 0.7151
Guanylate kinase P15454 KGUA_YEAST Saccharomyces cerevisiae 3 0.7151
Cytohesin-2 Q99418 CYH2_HUMAN Homo sapiens 3 0.7149
Prothrombin P00734 THRB_HUMAN Homo sapiens 2 0.7149
Prothrombin P00734 THRB_HUMAN Homo sapiens 2 0.7149
Cytohesin-2 Q99418 CYH2_HUMAN Homo sapiens 3 0.7149
DNA (cytosine-5)-methyltransferase 1 Q9AXT8 H32_ARATH Zea mays 3 0.7148
DNA (cytosine-5)-methyltransferase 1 Q9AXT8 H32_ARATH Zea mays 3 0.7148
Proto-oncogene tyrosine-protein kinase receptor Ret P07949 RET_HUMAN Homo sapiens 3 0.7147
Proto-oncogene tyrosine-protein kinase receptor Ret P07949 RET_HUMAN Homo sapiens 3 0.7147
Poly [ADP-ribose] polymerase tankyrase-2 Q9H2K2 TNKS2_HUMAN Homo sapiens 3 0.7143
Poly [ADP-ribose] polymerase tankyrase-2 Q9H2K2 TNKS2_HUMAN Homo sapiens 3 0.7143
Glucose-1-phosphate thymidylyltransferase Q9HU22 Q9HU22_PSEAE Pseudomonas aeruginosa 3 0.7142
Glucose-1-phosphate thymidylyltransferase Q9HU22 Q9HU22_PSEAE Pseudomonas aeruginosa 3 0.7142
Flavin reductase like domain-containing protein Q4UKE8 Q4UKE8_RICFE Rickettsia felis 3 0.7141
Flavin reductase like domain-containing protein Q4UKE8 Q4UKE8_RICFE Rickettsia felis 3 0.7141
TGF-beta receptor type-1 P36897 TGFR1_HUMAN Homo sapiens 3 0.7140
TGF-beta receptor type-1 P36897 TGFR1_HUMAN Homo sapiens 3 0.7140
Cyclin-dependent kinase 2 P24941 CDK2_HUMAN Homo sapiens 3 0.7138
Cyclin-dependent kinase 2 P24941 CDK2_HUMAN Homo sapiens 3 0.7138
Glutamate receptor 2 P19491 GRIA2_RAT Rattus norvegicus 2 0.7136
Glutamate receptor 2 P19491 GRIA2_RAT Rattus norvegicus 2 0.7136
HTH-type transcriptional repressor PurR P0ACP7 PURR_ECOLI Escherichia coli 2 0.7135
HTH-type transcriptional repressor PurR P0ACP7 PURR_ECOLI Escherichia coli 2 0.7135
Cytidine and deoxycytidylate deaminase zinc-binding region Q82Y41 Q82Y41_NITEU Nitrosomonas europaea 3 0.7133
Cytidine and deoxycytidylate deaminase zinc-binding region Q82Y41 Q82Y41_NITEU Nitrosomonas europaea 3 0.7133
7-methylguanosine phosphate-specific 5'-nucleotidase Q9W197 5NT3B_DROME Drosophila melanogaster 3 0.7132
7-methylguanosine phosphate-specific 5'-nucleotidase Q9W197 5NT3B_DROME Drosophila melanogaster 3 0.7132
Tyrosine-protein kinase receptor TYRO3 P55144 TYRO3_MOUSE Mus musculus 3 0.7131
Tyrosine-protein kinase receptor TYRO3 P55144 TYRO3_MOUSE Mus musculus 3 0.7131
Protein mono-ADP-ribosyltransferase PARP15 Q460N3 PAR15_HUMAN Homo sapiens 4 0.7130
Protein mono-ADP-ribosyltransferase PARP15 Q460N3 PAR15_HUMAN Homo sapiens 4 0.7130
Queuine tRNA-ribosyltransferase P28720 TGT_ZYMMO Zymomonas mobilis subsp. mobilis 3 0.7129
Queuine tRNA-ribosyltransferase P28720 TGT_ZYMMO Zymomonas mobilis subsp. mobilis 3 0.7129
Serine/threonine-protein kinase pim-1 P11309 PIM1_HUMAN Homo sapiens 3 0.7128
Serine/threonine-protein kinase pim-1 P11309 PIM1_HUMAN Homo sapiens 3 0.7128
F420-dependent methylenetetrahydromethanopterin dehydrogenase P94951 MTD_METKA Methanopyrus kandleri 2 0.7127
F420-dependent methylenetetrahydromethanopterin dehydrogenase P94951 MTD_METKA Methanopyrus kandleri 2 0.7127
17-beta-hydroxysteroid dehydrogenase type 1 P14061 DHB1_HUMAN Homo sapiens 3 0.7126
17-beta-hydroxysteroid dehydrogenase type 1 P14061 DHB1_HUMAN Homo sapiens 3 0.7126
Bifunctional dihydrofolate reductase-thymidylate synthase Q07422 DRTS_TOXGO Toxoplasma gondii 3 0.7125
Beta-secretase 1 P56817 BACE1_HUMAN Homo sapiens 2 0.7125
Bifunctional dihydrofolate reductase-thymidylate synthase Q07422 DRTS_TOXGO Toxoplasma gondii 3 0.7125
Beta-secretase 1 P56817 BACE1_HUMAN Homo sapiens 2 0.7125
Acetylcholinesterase P21836 ACES_MOUSE Mus musculus 2 0.7122
Acetylcholinesterase P21836 ACES_MOUSE Mus musculus 2 0.7122
APH(2'')-Id O68183 O68183_ENTCA Enterococcus casseliflavus 3 0.7121
Cyclic nucleotide-binding domain-containing protein E0RR11 E0RR11_SPITD Spirochaeta thermophila 3 0.7121
APH(2'')-Id O68183 O68183_ENTCA Enterococcus casseliflavus 3 0.7121
Cyclic nucleotide-binding domain-containing protein E0RR11 E0RR11_SPITD Spirochaeta thermophila 3 0.7121
Isoliquiritigenin 2'-O-methyltransferase P93324 CHOMT_MEDSA Medicago sativa 3 0.7119
Isoliquiritigenin 2'-O-methyltransferase P93324 CHOMT_MEDSA Medicago sativa 3 0.7119
Carbonic anhydrase 2 P00918 CAH2_HUMAN Homo sapiens 2 0.7118
Prostaglandin G/H synthase 2 Q05769 PGH2_MOUSE Mus musculus 4 0.7118
Basic phospholipase A2 VRV-PL-VIIIa P59071 PA2B8_DABRR Daboia russelii 2 0.7118
Carbonic anhydrase 2 P00918 CAH2_HUMAN Homo sapiens 2 0.7118
Prostaglandin G/H synthase 2 Q05769 PGH2_MOUSE Mus musculus 4 0.7118
Basic phospholipase A2 VRV-PL-VIIIa P59071 PA2B8_DABRR Daboia russelii 2 0.7118
Tau-tubulin kinase 1 Q5TCY1 TTBK1_HUMAN Homo sapiens 3 0.7112
Tau-tubulin kinase 1 Q5TCY1 TTBK1_HUMAN Homo sapiens 3 0.7112
Casein kinase II subunit alpha P68400 CSK21_HUMAN Homo sapiens 3 0.7109
Casein kinase II subunit alpha P68400 CSK21_HUMAN Homo sapiens 3 0.7109
Endoplasmin P41148 ENPL_CANLF Canis lupus familiaris 2 0.7107
Endoplasmin P41148 ENPL_CANLF Canis lupus familiaris 2 0.7107
clade A/E 93TH057 HIV-1 gp120 core A0A0M3KKW9 A0A0M3KKW9_9HIV1 Human immunodeficiency virus 1 2 0.7107
clade A/E 93TH057 HIV-1 gp120 core A0A0M3KKW9 A0A0M3KKW9_9HIV1 Human immunodeficiency virus 1 2 0.7107
Prothrombin P00734 THRB_HUMAN Homo sapiens 3 0.7106
Prothrombin P00734 THRB_HUMAN Homo sapiens 3 0.7106
Heat shock cognate 71 kDa protein P11142 HSP7C_HUMAN Homo sapiens 3 0.7102
Heat shock cognate 71 kDa protein P11142 HSP7C_HUMAN Homo sapiens 3 0.7102
2',3'-cyclic-nucleotide 3'-phosphodiesterase P16330 CN37_MOUSE Mus musculus 2 0.7102
2',3'-cyclic-nucleotide 3'-phosphodiesterase P16330 CN37_MOUSE Mus musculus 2 0.7102
Neuropilin-1 O14786 NRP1_HUMAN Homo sapiens 3 0.7100
Neuropilin-1 O14786 NRP1_HUMAN Homo sapiens 3 0.7100
Histone deacetylase-like amidohydrolase Q70I53 HDAH_ALCSD Alcaligenes sp.) 2 0.7096
Histone deacetylase-like amidohydrolase Q70I53 HDAH_ALCSD Alcaligenes sp.) 2 0.7096
Class B acid phosphatase P0AE22 APHA_ECOLI Escherichia coli 2 0.7092
Class B acid phosphatase P0AE22 APHA_ECOLI Escherichia coli 2 0.7092
Type II methyltransferase M.TaqI P14385 MTTA_THEAQ Thermus aquaticus 3 0.7091
Type II methyltransferase M.TaqI P14385 MTTA_THEAQ Thermus aquaticus 3 0.7091
Aurora kinase A O14965 AURKA_HUMAN Homo sapiens 3 0.7090
Aurora kinase A O14965 AURKA_HUMAN Homo sapiens 3 0.7090
Tyrosine-protein kinase JAK2 O60674 JAK2_HUMAN Homo sapiens 3 0.7088
Tyrosine-protein kinase JAK2 O60674 JAK2_HUMAN Homo sapiens 3 0.7088
Tetracycline repressor protein class D P0ACT4 TETR4_ECOLX Escherichia coli 3 0.7087
Tetracycline repressor protein class D P0ACT4 TETR4_ECOLX Escherichia coli 3 0.7087
Pentaerythritol tetranitrate reductase P71278 P71278_ENTCL Enterobacter cloacae 2 0.7084
Pentaerythritol tetranitrate reductase P71278 P71278_ENTCL Enterobacter cloacae 2 0.7084
Replicase polyprotein 1ab P0C6X7 R1AB_CVHSA Human SARS coronavirus 3 0.7083
Replicase polyprotein 1ab P0C6X7 R1AB_CVHSA Human SARS coronavirus 3 0.7083
Calmodulin-domain protein kinase 1, putative A3FQ16 A3FQ16_CRYPI Cryptosporidium parvum 3 0.7083
Calmodulin-domain protein kinase 1, putative A3FQ16 A3FQ16_CRYPI Cryptosporidium parvum 3 0.7083
Carboxypeptidase A1 P00730 CBPA1_BOVIN Bos taurus 2 0.7081
Carboxypeptidase A1 P00730 CBPA1_BOVIN Bos taurus 2 0.7081
Ribonuclease 4 P15468 RNAS4_PIG Sus scrofa 2 0.7080
Ribonuclease 4 P15468 RNAS4_PIG Sus scrofa 2 0.7080
Hematopoietic prostaglandin D synthase O60760 HPGDS_HUMAN Homo sapiens 2 0.7078
Hematopoietic prostaglandin D synthase O60760 HPGDS_HUMAN Homo sapiens 2 0.7078
Glutaminyl-peptide cyclotransferase Q16769 QPCT_HUMAN Homo sapiens 3 0.7075
Glutaminyl-peptide cyclotransferase Q16769 QPCT_HUMAN Homo sapiens 3 0.7075
Gag-Pol polyprotein P03369 POL_HV1A2 Human immunodeficiency virus type 1 group M subtype B 3 0.7075
Gag-Pol polyprotein P03369 POL_HV1A2 Human immunodeficiency virus type 1 group M subtype B 3 0.7075
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase P62617 ISPF_ECOLI Escherichia coli 3 0.7074
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase P62617 ISPF_ECOLI Escherichia coli 3 0.7074
Aldo-keto reductase family 1 member B1 P15121 ALDR_HUMAN Homo sapiens 2 0.7073
Aldo-keto reductase family 1 member B1 P15121 ALDR_HUMAN Homo sapiens 2 0.7073
Amino-acid acetyltransferase Q5FAK7 Q5FAK7_NEIG1 Neisseria gonorrhoeae 2 0.7070
Amino-acid acetyltransferase Q5FAK7 Q5FAK7_NEIG1 Neisseria gonorrhoeae 2 0.7070
Poly [ADP-ribose] polymerase tankyrase-2 Q9H2K2 TNKS2_HUMAN Homo sapiens 4 0.7067
Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 2 O95340 PAPS2_HUMAN Homo sapiens 2 0.7067
Poly [ADP-ribose] polymerase tankyrase-2 Q9H2K2 TNKS2_HUMAN Homo sapiens 4 0.7067
Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 2 O95340 PAPS2_HUMAN Homo sapiens 2 0.7067
Endothiapepsin P11838 CARP_CRYPA Cryphonectria parasitica 3 0.7066
Endoplasmin P41148 ENPL_CANLF Canis lupus familiaris 3 0.7066
Endothiapepsin P11838 CARP_CRYPA Cryphonectria parasitica 3 0.7066
Endoplasmin P41148 ENPL_CANLF Canis lupus familiaris 3 0.7066
Type II methyltransferase M.TaqI P14385 MTTA_THEAQ Thermus aquaticus 3 0.7063
Type II methyltransferase M.TaqI P14385 MTTA_THEAQ Thermus aquaticus 3 0.7063
Mitogen-activated protein kinase 14 Q16539 MK14_HUMAN Homo sapiens 3 0.7062
Mitogen-activated protein kinase 14 Q16539 MK14_HUMAN Homo sapiens 3 0.7062
Peripheral plasma membrane protein CASK O14936 CSKP_HUMAN Homo sapiens 3 0.7062
Peripheral plasma membrane protein CASK O14936 CSKP_HUMAN Homo sapiens 3 0.7062
Ribonuclease TTHA0252 Q5SLP1 RNSE_THET8 Thermus thermophilus 3 0.7061
Ribonuclease TTHA0252 Q5SLP1 RNSE_THET8 Thermus thermophilus 3 0.7061
Beta-hexosaminidase Q9KU37 NAGZ_VIBCH Vibrio cholerae serotype O1 3 0.7061
Beta-hexosaminidase Q9KU37 NAGZ_VIBCH Vibrio cholerae serotype O1 3 0.7061
Anthranilate phosphoribosyltransferase P00500 TRPD_ACIAD Acinetobacter baylyi 2 0.7060
Anthranilate phosphoribosyltransferase P00500 TRPD_ACIAD Acinetobacter baylyi 2 0.7060
NAD(P) transhydrogenase subunit alpha part 1 Q2RSB2 PNTAA_RHORT Rhodospirillum rubrum 3 0.7059
NAD(P) transhydrogenase subunit alpha part 1 Q2RSB2 PNTAA_RHORT Rhodospirillum rubrum 3 0.7059
Type II methyltransferase M.TaqI P14385 MTTA_THEAQ Thermus aquaticus 3 0.7056
Fibroblast growth factor receptor 2 P21802 FGFR2_HUMAN Homo sapiens 3 0.7056
Type II methyltransferase M.TaqI P14385 MTTA_THEAQ Thermus aquaticus 3 0.7056
Fibroblast growth factor receptor 2 P21802 FGFR2_HUMAN Homo sapiens 3 0.7056
Metallo-beta-lactamase type 2 C7C422 BLAN1_KLEPN Klebsiella pneumoniae 2 0.7055
Metallo-beta-lactamase type 2 C7C422 BLAN1_KLEPN Klebsiella pneumoniae 2 0.7055
Riboflavin synthase P0AFU8 RISA_ECOLI Escherichia coli 3 0.7052
Seminal ribonuclease P00669 RNS_BOVIN Bos taurus 3 0.7052
Seminal ribonuclease P00669 RNS_BOVIN Bos taurus 3 0.7052
Riboflavin synthase P0AFU8 RISA_ECOLI Escherichia coli 3 0.7052
Acetylcholinesterase P22303 ACES_HUMAN Homo sapiens 3 0.7051
Acetylcholinesterase P22303 ACES_HUMAN Homo sapiens 3 0.7051
Thymidine kinase P0DTH5 KITH_HHV11 Human herpesvirus 1 2 0.7047
Thymidine kinase P0DTH5 KITH_HHV11 Human herpesvirus 1 2 0.7047
Fructose-1,6-bisphosphatase 1 P09467 F16P1_HUMAN Homo sapiens 2 0.7046
Fructose-1,6-bisphosphatase 1 P09467 F16P1_HUMAN Homo sapiens 2 0.7046
Disintegrin and metalloproteinase domain-containing protein 17 P78536 ADA17_HUMAN Homo sapiens 2 0.7044
Disintegrin and metalloproteinase domain-containing protein 17 P78536 ADA17_HUMAN Homo sapiens 2 0.7044
Sulfotransferase 1A1 P50225 ST1A1_HUMAN Homo sapiens 2 0.7043
Sulfotransferase 1A1 P50225 ST1A1_HUMAN Homo sapiens 2 0.7043
Acetolactate synthase, chloroplastic P17597 ILVB_ARATH Arabidopsis thaliana 2 0.7042
Acetolactate synthase, chloroplastic P17597 ILVB_ARATH Arabidopsis thaliana 2 0.7042
Poly [ADP-ribose] polymerase 1 P09874 PARP1_HUMAN Homo sapiens 3 0.7041
Poly [ADP-ribose] polymerase 1 P09874 PARP1_HUMAN Homo sapiens 3 0.7041
Catechol O-methyltransferase P22734 COMT_RAT Rattus norvegicus 3 0.7038
Catechol O-methyltransferase P22734 COMT_RAT Rattus norvegicus 3 0.7038
Pantothenate kinase P9WPA7 COAA_MYCTU Mycobacterium tuberculosis 3 0.7037
Pantothenate kinase P9WPA7 COAA_MYCTU Mycobacterium tuberculosis 3 0.7037
Glutathione S-transferase P P09211 GSTP1_HUMAN Homo sapiens 2 0.7036
Glutathione S-transferase P P09211 GSTP1_HUMAN Homo sapiens 2 0.7036
Holliday junction branch migration complex subunit RuvB Q9PMT7 RUVB_CAMJE Campylobacter jejuni subsp. jejuni serotype O:2 2 0.7034
Holliday junction branch migration complex subunit RuvB Q9PMT7 RUVB_CAMJE Campylobacter jejuni subsp. jejuni serotype O:2 2 0.7034
Heat shock protein HSP 90-alpha P07900 HS90A_HUMAN Homo sapiens 2 0.7032
Heat shock protein HSP 90-alpha P07900 HS90A_HUMAN Homo sapiens 2 0.7032
HTH-type transcriptional repressor PurR P0ACP7 PURR_ECOLI Escherichia coli 3 0.7031
HTH-type transcriptional repressor PurR P0ACP7 PURR_ECOLI Escherichia coli 3 0.7031
Nickel-binding periplasmic protein P33590 NIKA_ECOLI Escherichia coli 2 0.7026
Nickel-binding periplasmic protein P33590 NIKA_ECOLI Escherichia coli 2 0.7026
MAP kinase-activated protein kinase 2 P49137 MAPK2_HUMAN Homo sapiens 3 0.7020
Catabolite activator protein C3SQJ7 C3SQJ7_ECOLX Escherichia coli 3 0.7020
Catabolite activator protein C3SQJ7 C3SQJ7_ECOLX Escherichia coli 3 0.7020
MAP kinase-activated protein kinase 2 P49137 MAPK2_HUMAN Homo sapiens 3 0.7020
Gag-Pol polyprotein P03369 POL_HV1A2 Human immunodeficiency virus type 1 group M subtype B 3 0.7019
Class B acid phosphatase Q540U1 APHA_SALTM Salmonella typhimurium 3 0.7019
Homoserine dehydrogenase P31116 DHOM_YEAST Saccharomyces cerevisiae 3 0.7019
Gag-Pol polyprotein P03369 POL_HV1A2 Human immunodeficiency virus type 1 group M subtype B 3 0.7019
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform P48736 PK3CG_HUMAN Homo sapiens 3 0.7019
Homoserine dehydrogenase P31116 DHOM_YEAST Saccharomyces cerevisiae 3 0.7019
Class B acid phosphatase Q540U1 APHA_SALTM Salmonella typhimurium 3 0.7019
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform P48736 PK3CG_HUMAN Homo sapiens 3 0.7019
Gag-Pol polyprotein P03366 POL_HV1B1 Human immunodeficiency virus type 1 group M subtype B 3 0.7018
Urokinase-type plasminogen activator P00749 UROK_HUMAN Homo sapiens 2 0.7018
Gag-Pol polyprotein P03366 POL_HV1B1 Human immunodeficiency virus type 1 group M subtype B 3 0.7018
Urokinase-type plasminogen activator P00749 UROK_HUMAN Homo sapiens 2 0.7018
Cyclic nucleotide-binding domain-containing protein E0RR11 E0RR11_SPITD Spirochaeta thermophila 2 0.7016
Cyclic nucleotide-binding domain-containing protein E0RR11 E0RR11_SPITD Spirochaeta thermophila 2 0.7016
16S rRNA (guanine(1405)-N(7))-methyltransferase Q763K9 Q763K9_ECOLX Escherichia coli 3 0.7012
16S rRNA (guanine(1405)-N(7))-methyltransferase Q763K9 Q763K9_ECOLX Escherichia coli 3 0.7012
Enoyl-[acyl-carrier-protein] reductase [NADH] P9WGR1 INHA_MYCTU Mycobacterium tuberculosis 3 0.7010
Protocatechuate 3,4-dioxygenase beta chain P00437 PCXB_PSEPU Pseudomonas putida 2 0.7010
Protein mono-ADP-ribosyltransferase PARP10 Q53GL7 PAR10_HUMAN Homo sapiens 3 0.7010
Adenosine 5'-monophosphoramidase HINT1 P80912 HINT1_RABIT Oryctolagus cuniculus 2 0.7010
Adenosine 5'-monophosphoramidase HINT1 P80912 HINT1_RABIT Oryctolagus cuniculus 2 0.7010
Enoyl-[acyl-carrier-protein] reductase [NADH] P9WGR1 INHA_MYCTU Mycobacterium tuberculosis 3 0.7010
Serine/threonine-protein kinase PLK1 P53350 PLK1_HUMAN Homo sapiens 3 0.7010
Protocatechuate 3,4-dioxygenase beta chain P00437 PCXB_PSEPU Pseudomonas putida 2 0.7010
Protein mono-ADP-ribosyltransferase PARP10 Q53GL7 PAR10_HUMAN Homo sapiens 3 0.7010
Serine/threonine-protein kinase PLK1 P53350 PLK1_HUMAN Homo sapiens 3 0.7010
Lactotransferrin P24627 TRFL_BOVIN Bos taurus 2 0.7009
Lactotransferrin P24627 TRFL_BOVIN Bos taurus 2 0.7009
Thymidylate synthase Q4JQW2 TYSY_VZVO Varicella-zoster virus 3 0.7008
cAMP-dependent protein kinase type I-alpha regulatory subunit P00514 KAP0_BOVIN Bos taurus 2 0.7008
cAMP-dependent protein kinase type II-beta regulatory subunit P12369 KAP3_RAT Rattus norvegicus 2 0.7008
Thymidylate synthase Q4JQW2 TYSY_VZVO Varicella-zoster virus 3 0.7008
cAMP-dependent protein kinase type I-alpha regulatory subunit P00514 KAP0_BOVIN Bos taurus 2 0.7008
cAMP-dependent protein kinase type II-beta regulatory subunit P12369 KAP3_RAT Rattus norvegicus 2 0.7008
2',3'-cyclic-nucleotide 3'-phosphodiesterase P16330 CN37_MOUSE Mus musculus 2 0.7007
Queuine tRNA-ribosyltransferase P28720 TGT_ZYMMO Zymomonas mobilis subsp. mobilis 2 0.7007
2',3'-cyclic-nucleotide 3'-phosphodiesterase P16330 CN37_MOUSE Mus musculus 2 0.7007
Queuine tRNA-ribosyltransferase P28720 TGT_ZYMMO Zymomonas mobilis subsp. mobilis 2 0.7007
Activin receptor type-1 Q04771 ACVR1_HUMAN Homo sapiens 3 0.7006
Activin receptor type-1 Q04771 ACVR1_HUMAN Homo sapiens 3 0.7006
Formate--tetrahydrofolate ligase P21164 FTHS_MOOTH Moorella thermoacetica 2 0.7006
Formate--tetrahydrofolate ligase P21164 FTHS_MOOTH Moorella thermoacetica 2 0.7006
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 P04191 AT2A1_RABIT Oryctolagus cuniculus 3 0.7005
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 P04191 AT2A1_RABIT Oryctolagus cuniculus 3 0.7005
APH(2'')-Id O68183 O68183_ENTCA Enterococcus casseliflavus 3 0.7005
APH(2'')-Id O68183 O68183_ENTCA Enterococcus casseliflavus 3 0.7005
Transitional endoplasmic reticulum ATPase P55072 TERA_HUMAN Homo sapiens 3 0.7003
Transitional endoplasmic reticulum ATPase P55072 TERA_HUMAN Homo sapiens 3 0.7003
Proliferating cell nuclear antigen P12004 PCNA_HUMAN Homo sapiens 2 0.7002
Proliferating cell nuclear antigen P12004 PCNA_HUMAN Homo sapiens 2 0.7002
Beta-1 adrenergic receptor P07700 ADRB1_MELGA Meleagris gallopavo 3 0.7000
Beta-1 adrenergic receptor P07700 ADRB1_MELGA Meleagris gallopavo 3 0.7000

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