(±)-enterolactone - Compound Card

(±)-enterolactone

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(±)-enterolactone

Structure
Zoomed Structure
  • Family: Urticaceae
  • Kingdom: Plantae
  • Class: Lignan
Canonical Smiles Oc1cccc(c1)C[C@H]1C(=O)OC[C@@H]1Cc1cccc(c1)O
InChI InChI=1S/C18H18O4/c19-15-5-1-3-12(8-15)7-14-11-22-18(21)17(14)10-13-4-2-6-16(20)9-13/h1-6,8-9,14,17,19-20H,7,10-11H2/t14-,17+/m0/s1
InChIKey HVDGDHBAMCBBLR-WMLDXEAASA-N
Formula C18H18O4
HBA 4
HBD 2
MW 298.34
Rotatable Bonds 4
TPSA 66.76
LogP 2.67
Number Rings 3
Number Aromatic Rings 2
Heavy Atom Count 22
Formal Charge 0
Fraction CSP3 0.28
Exact Mass 298.12
Number of Lipinski Rule Violations 0
# Species Family Kingdom NCBI Taxonomy ID
1 Urtica dioica Urticaceae Plantae 3501

Showing of synonyms

  • Schöttner M, Reiner J, et al. (1997). Lignans from the roots of Urtica dioica and their metabolites bind to human sex hormone binding globulin (SHBG). Planta Medica,1997,63(6),529-532. [View] [PubMed]
Pubchem: 10685477
Nmrshiftdb2: 70073144
CPRiL: 63329
Structure

SMILES: c1ccccc1CC(C2=O)C(CO2)Cc3ccccc3

Level: 2

Mol. Weight: 266.34 g/mol

Structure

SMILES: O=C1CC(CO1)Cc2ccccc2

Level: 1

Mol. Weight: 176.22 g/mol

Structure

SMILES: O1CCC(C1=O)Cc2ccccc2

Level: 1

Mol. Weight: 176.22 g/mol

Structure

SMILES: O=C1CCCO1

Level: 0

Mol. Weight: 86.09 g/mol

Structure

SMILES: c1ccccc1

Level: 0

Mol. Weight: 78.11 g/mol

Vasorelaxant

Absorption

Caco-2 (logPapp)
-4.71
Human Oral Bioavailability 20%
Bioavailable
Human Intestinal Absorption
Absorbed
Madin-Darby Canine Kidney
-4.870
Human Oral Bioavailability 50%
Bioavailable
P-Glycoprotein Inhibitor
Non-Inhibitor
P-Glycoprotein Substrate
Non-Substrate
Skin Permeability
-1.79

Distribution

Blood-Brain Barrier (CNS)
-
Blood-Brain Barrier
Non-Penetrable
Fraction Unbound (Human)
0.730
Plasma Protein Binding
85.85
Steady State Volume of Distribution
-

Metabolism

Breast Cancer Resistance Protein
Inhibitor
CYP 1A2 Inhibitor
Inhibitor
CYP 1A2 Substrate
Substrate
CYP 2C19 Inhibitor
Inhibitor
CYP 2C19 Substrate
Non-Substrate
CYP 2C9 Inhibitor
Inhibitor
CYP 2C9 Substrate
Substrate
CYP 2D6 Inhibitor
Non-Inhibitor
CYP 2D6 Substrate
Non-Substrate
CYP 3A4 Inhibitor
Inhibitor
CYP 3A4 Substrate
Non-Substrate
OATP1B1
Non-Inhibitor
OATP1B3
Non-Inhibitor

Excretion

Clearance
5.470
Organic Cation Transporter 2
Non-Inhibitor
Half-Life of Drug
-

Toxicity

AMES Mutagenesis
Safe
Avian
Safe
Bee
Toxic
Bioconcentration Factor
1.000
Biodegradation
Safe
Carcinogenesis
Safe
Crustacean
Toxic
Liver Injury I (DILI)
Toxic
Eye Corrosion
Safe
Eye Irritation
Toxic
Maximum Tolerated Dose
0.480
Liver Injury II
Toxic
hERG Blockers
Toxic
Daphnia Maga
4.810
Micronucleos
Toxic
NR-AhR
Safe
NR-AR
Safe
NR-AR-LBD
Safe
NR-Aromatase
Safe
NR-ER
Toxic
NR-ER-LBD
Safe
NR-GR
Safe
NR-PPAR-gamma
Safe
NR-TR
Safe
T. Pyriformis
2.680
Rat (Acute)
1.740
Rat (Chronic Oral)
2.090
Fathead Minnow
4.310
Respiratory Disease
Toxic
Skin Sensitisation
Toxic
SR-ARE
Safe
SR-ATAD5
Safe
SR-HSE
Safe
SR-MMP
Toxic
SR-p53
Safe

General Properties

Boiling Point
421.490
Hydration Free Energy
-9.420
Log(D) at pH=7.4
2.960
Log(P)
2.33
Log S
-3.05
Log(Vapor Pressure)
-8.09
Melting Point
185.73
pKa Acid
8.82
pKa Basic
6.25
Protein Name UniProt ID Entry Name Species #Pharmacophore Points Probability (0.7 ≤ Tversky Score ≤ 1.0)
Serine/threonine-protein kinase 10 O94804 STK10_HUMAN Homo sapiens 3 0.9652
Serine/threonine-protein kinase 10 O94804 STK10_HUMAN Homo sapiens 3 0.9652
Serine/threonine-protein kinase 24 Q9Y6E0 STK24_HUMAN Homo sapiens 3 0.9577
Serine/threonine-protein kinase 24 Q9Y6E0 STK24_HUMAN Homo sapiens 3 0.9577
Chitinase A Q9AMP1 Q9AMP1_VIBHA Vibrio harveyi 3 0.9570
Chitinase A Q9AMP1 Q9AMP1_VIBHA Vibrio harveyi 3 0.9570
Nitric oxide synthase, inducible P29477 NOS2_MOUSE Mus musculus 3 0.9563
Nitric oxide synthase, inducible P29477 NOS2_MOUSE Mus musculus 3 0.9563
Serine/threonine-protein kinase pim-1 P11309 PIM1_HUMAN Homo sapiens 3 0.9530
Serine/threonine-protein kinase pim-1 P11309 PIM1_HUMAN Homo sapiens 3 0.9530
Acetolactate synthase, chloroplastic P17597 ILVB_ARATH Arabidopsis thaliana 3 0.9506
Acetolactate synthase, chloroplastic P17597 ILVB_ARATH Arabidopsis thaliana 3 0.9506
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial Q15119 PDK2_HUMAN Homo sapiens 3 0.9462
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial Q15119 PDK2_HUMAN Homo sapiens 3 0.9462
D-aminoacyl-tRNA deacylase Q8IIS0 DTD_PLAF7 Plasmodium falciparum 3 0.9428
D-aminoacyl-tRNA deacylase Q8IIS0 DTD_PLAF7 Plasmodium falciparum 3 0.9428
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A Q9QYJ6 PDE10_RAT Rattus norvegicus 3 0.9421
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A Q9QYJ6 PDE10_RAT Rattus norvegicus 3 0.9421
3',5'-cyclic-AMP phosphodiesterase 4D Q08499 PDE4D_HUMAN Homo sapiens 3 0.9352
3',5'-cyclic-AMP phosphodiesterase 4D Q08499 PDE4D_HUMAN Homo sapiens 3 0.9352
Sulfide-quinone reductase B7JBP8 SQRD_ACIF2 Acidithiobacillus ferrooxidans) 3 0.9348
Sulfide-quinone reductase B7JBP8 SQRD_ACIF2 Acidithiobacillus ferrooxidans) 3 0.9348
Mycocyclosin synthase P9WPP7 CP121_MYCTU Mycobacterium tuberculosis 3 0.9320
Mycocyclosin synthase P9WPP7 CP121_MYCTU Mycobacterium tuberculosis 3 0.9320
Heat shock protein HSP 90-alpha P07900 HS90A_HUMAN Homo sapiens 3 0.9315
Heat shock protein HSP 90-alpha P07900 HS90A_HUMAN Homo sapiens 3 0.9315
NAD-capped RNA hydrolase NudC P32664 NUDC_ECOLI Escherichia coli 3 0.9264
NAD-capped RNA hydrolase NudC P32664 NUDC_ECOLI Escherichia coli 3 0.9264
Streptogramin A acetyltransferase P50870 VATD_ENTFC Enterococcus faecium 3 0.9231
Streptogramin A acetyltransferase P50870 VATD_ENTFC Enterococcus faecium 3 0.9231
Acetolactate synthase, chloroplastic P17597 ILVB_ARATH Arabidopsis thaliana 3 0.9178
Acetolactate synthase, chloroplastic P17597 ILVB_ARATH Arabidopsis thaliana 3 0.9178
17beta-hydroxysteroid dehydrogenase O93874 O93874_COCLU Cochliobolus lunatus 3 0.9172
17beta-hydroxysteroid dehydrogenase O93874 O93874_COCLU Cochliobolus lunatus 3 0.9172
Nitric oxide synthase, inducible P29477 NOS2_MOUSE Mus musculus 3 0.9135
Nitric oxide synthase, inducible P29477 NOS2_MOUSE Mus musculus 3 0.9135
Nitric oxide synthase, inducible P29477 NOS2_MOUSE Mus musculus 3 0.9122
Nitric oxide synthase, inducible P29477 NOS2_MOUSE Mus musculus 3 0.9122
Nitric oxide synthase, inducible P29477 NOS2_MOUSE Mus musculus 3 0.9111
Nitric oxide synthase, inducible P29477 NOS2_MOUSE Mus musculus 3 0.9111
Epidermal growth factor receptor P00533 EGFR_HUMAN Homo sapiens 3 0.9106
Epidermal growth factor receptor P00533 EGFR_HUMAN Homo sapiens 3 0.9106
Nitric oxide synthase, inducible P29477 NOS2_MOUSE Mus musculus 3 0.9083
Nitric oxide synthase, inducible P29477 NOS2_MOUSE Mus musculus 3 0.9083
Lactotransferrin P24627 TRFL_BOVIN Bos taurus 3 0.9078
Lactotransferrin P24627 TRFL_BOVIN Bos taurus 3 0.9078
Ras-related protein Ral-B P11234 RALB_HUMAN Homo sapiens 3 0.9055
Ras-related protein Ral-B P11234 RALB_HUMAN Homo sapiens 3 0.9055
Chitinase Q54276 Q54276_SERMA Serratia marcescens 3 0.9039
Chitinase Q54276 Q54276_SERMA Serratia marcescens 3 0.9039
Rhodopsin kinase GRK1 P28327 GRK1_BOVIN Bos taurus 3 0.9026
Rhodopsin kinase GRK1 P28327 GRK1_BOVIN Bos taurus 3 0.9026
Peroxisome proliferator-activated receptor gamma P37231 PPARG_HUMAN Homo sapiens 3 0.8974
Peroxisome proliferator-activated receptor gamma P37231 PPARG_HUMAN Homo sapiens 3 0.8974
HTH-type transcriptional regulator QacR P0A0N4 QACR_STAAU Staphylococcus aureus 4 0.8969
HTH-type transcriptional regulator QacR P0A0N4 QACR_STAAU Staphylococcus aureus 4 0.8969
Nitric oxide synthase, inducible P29477 NOS2_MOUSE Mus musculus 3 0.8962
Nitric oxide synthase, inducible P29477 NOS2_MOUSE Mus musculus 3 0.8962
Tetracycline repressor protein class D P0ACT4 TETR4_ECOLX Escherichia coli 3 0.8960
Tetracycline repressor protein class D P0ACT4 TETR4_ECOLX Escherichia coli 3 0.8960
Stromelysin-1 P08254 MMP3_HUMAN Homo sapiens 3 0.8944
Stromelysin-1 P08254 MMP3_HUMAN Homo sapiens 3 0.8944
Flavonoid 3-O-glucosyltransferase A6XNC6 UGFGT_MEDTR Medicago truncatula 3 0.8900
Flavonoid 3-O-glucosyltransferase A6XNC6 UGFGT_MEDTR Medicago truncatula 3 0.8900
Cytochrome P450 1A1 P04798 CP1A1_HUMAN Homo sapiens 3 0.8897
Cytochrome P450 1A1 P04798 CP1A1_HUMAN Homo sapiens 3 0.8897
Nodulin-13 P93330 NOD13_MEDTR Medicago truncatula 3 0.8890
Nodulin-13 P93330 NOD13_MEDTR Medicago truncatula 3 0.8890
Epidermal growth factor receptor P00533 EGFR_HUMAN Homo sapiens 3 0.8877
Epidermal growth factor receptor P00533 EGFR_HUMAN Homo sapiens 3 0.8877
Heat shock protein HSP 90-alpha P07900 HS90A_HUMAN Homo sapiens 3 0.8865
Heat shock protein HSP 90-alpha P07900 HS90A_HUMAN Homo sapiens 3 0.8865
Tyrosine-protein kinase JAK2 O60674 JAK2_HUMAN Homo sapiens 3 0.8864
Tyrosine-protein kinase JAK2 O60674 JAK2_HUMAN Homo sapiens 3 0.8864
Mitogen-activated protein kinase 8 P45983 MK08_HUMAN Homo sapiens 3 0.8854
Mitogen-activated protein kinase 8 P45983 MK08_HUMAN Homo sapiens 3 0.8854
Acetylcholinesterase P22303 ACES_HUMAN Homo sapiens 3 0.8852
Acetylcholinesterase P22303 ACES_HUMAN Homo sapiens 3 0.8852
Glycogen synthase kinase-3 beta P49841 GSK3B_HUMAN Homo sapiens 3 0.8805
Glycogen synthase kinase-3 beta P49841 GSK3B_HUMAN Homo sapiens 3 0.8805
Fibroblast growth factor receptor 1 P11362 FGFR1_HUMAN Homo sapiens 3 0.8791
Fibroblast growth factor receptor 1 P11362 FGFR1_HUMAN Homo sapiens 3 0.8791
Pancreatic alpha-amylase P04746 AMYP_HUMAN Homo sapiens 3 0.8775
Pancreatic alpha-amylase P04746 AMYP_HUMAN Homo sapiens 3 0.8775
Pyruvate kinase PKM P14618 KPYM_HUMAN Homo sapiens 3 0.8774
Pyruvate kinase PKM P14618 KPYM_HUMAN Homo sapiens 3 0.8774
Bromodomain-containing protein 2 P25440 BRD2_HUMAN Homo sapiens 3 0.8746
Bromodomain-containing protein 2 P25440 BRD2_HUMAN Homo sapiens 3 0.8746
Photosynthetic reaction center cytochrome c subunit P07173 CYCR_BLAVI Blastochloris viridis 3 0.8737
Photosynthetic reaction center cytochrome c subunit P07173 CYCR_BLAVI Blastochloris viridis 3 0.8737
Chalcone--flavanone isomerase 1 P28012 CFI1_MEDSA Medicago sativa 3 0.8719
Chalcone--flavanone isomerase 1 P28012 CFI1_MEDSA Medicago sativa 3 0.8719
Phospholipase A2, major isoenzyme P00592 PA21B_PIG Sus scrofa 3 0.8717
Phospholipase A2, major isoenzyme P00592 PA21B_PIG Sus scrofa 3 0.8717
Anthocyanidin 3-O-glucosyltransferase UFGT P51094 UFOG_VITVI Vitis vinifera 4 0.8710
Anthocyanidin 3-O-glucosyltransferase UFGT P51094 UFOG_VITVI Vitis vinifera 4 0.8710
Mitogen-activated protein kinase 1 P28482 MK01_HUMAN Homo sapiens 3 0.8687
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial Q15119 PDK2_HUMAN Homo sapiens 3 0.8687
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial Q15119 PDK2_HUMAN Homo sapiens 3 0.8687
Mitogen-activated protein kinase 1 P28482 MK01_HUMAN Homo sapiens 3 0.8687
ATP-dependent molecular chaperone HSP82 P02829 HSP82_YEAST Saccharomyces cerevisiae 3 0.8680
ATP-dependent molecular chaperone HSP82 P02829 HSP82_YEAST Saccharomyces cerevisiae 3 0.8680
Chalcone--flavanone isomerase 1 P28012 CFI1_MEDSA Medicago sativa 3 0.8675
Chalcone--flavanone isomerase 1 P28012 CFI1_MEDSA Medicago sativa 3 0.8675
Gag-Pol polyprotein P03369 POL_HV1A2 Human immunodeficiency virus type 1 group M subtype B 4 0.8669
Gag-Pol polyprotein P03369 POL_HV1A2 Human immunodeficiency virus type 1 group M subtype B 4 0.8669
Prothrombin P00734 THRB_HUMAN Homo sapiens 3 0.8641
Prothrombin P00734 THRB_HUMAN Homo sapiens 3 0.8641
Beta-adrenergic receptor kinase 1 P25098 ARBK1_HUMAN Homo sapiens 3 0.8631
Beta-adrenergic receptor kinase 1 P25098 ARBK1_HUMAN Homo sapiens 3 0.8631
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A Q9Y233 PDE10_HUMAN Homo sapiens 3 0.8622
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A Q9Y233 PDE10_HUMAN Homo sapiens 3 0.8622
Cyclic dipeptide N-prenyltransferase D1D8L6 D1D8L6_ASPFM Neosartorya fumigata 3 0.8607
Cyclic dipeptide N-prenyltransferase D1D8L6 D1D8L6_ASPFM Neosartorya fumigata 3 0.8607
Nitric oxide synthase, inducible P29477 NOS2_MOUSE Mus musculus 3 0.8590
Nitric oxide synthase, inducible P29477 NOS2_MOUSE Mus musculus 3 0.8590
Mitogen-activated protein kinase 14 Q16539 MK14_HUMAN Homo sapiens 3 0.8585
Mitogen-activated protein kinase 14 Q16539 MK14_HUMAN Homo sapiens 3 0.8585
histidine kinase O32393 O32393_ARTPT Arthrospira platensis 3 0.8584
histidine kinase O32393 O32393_ARTPT Arthrospira platensis 3 0.8584
Carnitine O-palmitoyltransferase 2, mitochondrial P18886 CPT2_RAT Rattus norvegicus 3 0.8563
Carnitine O-palmitoyltransferase 2, mitochondrial P18886 CPT2_RAT Rattus norvegicus 3 0.8563
Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase Q9TQS6 DHDH_MACFA Macaca fascicularis 3 0.8557
Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase Q9TQS6 DHDH_MACFA Macaca fascicularis 3 0.8557
RNA polymerase sigma factor SigA Q5SKW1 Q5SKW1_THET8 Thermus thermophilus 3 0.8550
RNA polymerase sigma factor SigA Q5SKW1 Q5SKW1_THET8 Thermus thermophilus 3 0.8550
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase Q8DNV6 Q8DNV6_STRR6 Streptococcus pneumoniae 3 0.8543
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase Q8DNV6 Q8DNV6_STRR6 Streptococcus pneumoniae 3 0.8543
Serine/threonine-protein kinase Chk1 O14757 CHK1_HUMAN Homo sapiens 3 0.8534
Serine/threonine-protein kinase Chk1 O14757 CHK1_HUMAN Homo sapiens 3 0.8534
Albumin P02768 ALBU_HUMAN Homo sapiens 3 0.8530
Albumin P02768 ALBU_HUMAN Homo sapiens 3 0.8530
Tau-tubulin kinase 1 Q5TCY1 TTBK1_HUMAN Homo sapiens 4 0.8529
Tau-tubulin kinase 1 Q5TCY1 TTBK1_HUMAN Homo sapiens 4 0.8529
Neocarzinostatin P0A3R9 NCZS_STRCZ Streptomyces carzinostaticus 3 0.8517
Neocarzinostatin P0A3R9 NCZS_STRCZ Streptomyces carzinostaticus 3 0.8517
Avidin P02701 AVID_CHICK Gallus gallus 3 0.8506
Avidin P02701 AVID_CHICK Gallus gallus 3 0.8506
Cytochrome P450 S6BVH1 S6BVH1_RHOER Rhodococcus erythropolis 3 0.8497
Cytochrome P450 S6BVH1 S6BVH1_RHOER Rhodococcus erythropolis 3 0.8497
Nitric oxide synthase, inducible P29477 NOS2_MOUSE Mus musculus 3 0.8493
Nitric oxide synthase, inducible P29477 NOS2_MOUSE Mus musculus 3 0.8493
TGF-beta-activated kinase 1 and MAP3K7-binding protein 1 Q15750 TAB1_HUMAN Homo sapiens 3 0.8475
TGF-beta-activated kinase 1 and MAP3K7-binding protein 1 Q15750 TAB1_HUMAN Homo sapiens 3 0.8475
HTH-type transcriptional repressor PurR P0ACP7 PURR_ECOLI Escherichia coli 3 0.8470
HTH-type transcriptional repressor PurR P0ACP7 PURR_ECOLI Escherichia coli 3 0.8470
Threonine synthase 1, chloroplastic Q9S7B5 THRC1_ARATH Arabidopsis thaliana 3 0.8438
Threonine synthase 1, chloroplastic Q9S7B5 THRC1_ARATH Arabidopsis thaliana 3 0.8438
Glutathione S-transferase F2 P46422 GSTF2_ARATH Arabidopsis thaliana 3 0.8416
Glutathione S-transferase F2 P46422 GSTF2_ARATH Arabidopsis thaliana 3 0.8416
Heat shock protein HSP 90-alpha P07900 HS90A_HUMAN Homo sapiens 3 0.8408
Heat shock protein HSP 90-alpha P07900 HS90A_HUMAN Homo sapiens 3 0.8408
Activin receptor type-1 Q04771 ACVR1_HUMAN Homo sapiens 3 0.8383
Activin receptor type-1 Q04771 ACVR1_HUMAN Homo sapiens 3 0.8383
Heat shock protein HSP 90-alpha P07900 HS90A_HUMAN Homo sapiens 3 0.8370
Heat shock protein HSP 90-alpha P07900 HS90A_HUMAN Homo sapiens 3 0.8370
Chalcone--flavanone isomerase 1 P28012 CFI1_MEDSA Medicago sativa 4 0.8309
Chalcone--flavanone isomerase 1 P28012 CFI1_MEDSA Medicago sativa 4 0.8309
Prothrombin P00734 THRB_HUMAN Homo sapiens 3 0.8285
Prothrombin P00734 THRB_HUMAN Homo sapiens 3 0.8285
Estrogen receptor P03372 ESR1_HUMAN Homo sapiens 3 0.8266
Estrogen receptor P03372 ESR1_HUMAN Homo sapiens 3 0.8266
DNA topoisomerase 4 subunit B H7C794 PARE_ENTFA Enterococcus faecalis 3 0.8236
DNA topoisomerase 4 subunit B H7C794 PARE_ENTFA Enterococcus faecalis 3 0.8236
Macrophage metalloelastase P39900 MMP12_HUMAN Homo sapiens 3 0.8230
Macrophage metalloelastase P39900 MMP12_HUMAN Homo sapiens 3 0.8230
HTH-type transcriptional regulator TtgR Q9AIU0 TTGR_PSEPT Pseudomonas putida 3 0.8228
HTH-type transcriptional regulator TtgR Q9AIU0 TTGR_PSEPT Pseudomonas putida 3 0.8228
Dihydrofolate reductase P00374 DYR_HUMAN Homo sapiens 3 0.8202
Dihydrofolate reductase P00374 DYR_HUMAN Homo sapiens 3 0.8202
Queuine tRNA-ribosyltransferase P28720 TGT_ZYMMO Zymomonas mobilis subsp. mobilis 3 0.8198
Queuine tRNA-ribosyltransferase P28720 TGT_ZYMMO Zymomonas mobilis subsp. mobilis 3 0.8198
ActVA 6 protein Q53908 Q53908_STRCH Streptomyces coelicolor 3 0.8188
ActVA 6 protein Q53908 Q53908_STRCH Streptomyces coelicolor 3 0.8188
Prothrombin P00734 THRB_HUMAN Homo sapiens 3 0.8187
Prothrombin P00734 THRB_HUMAN Homo sapiens 3 0.8187
Peptidyl-prolyl cis-trans isomerase FKBP1A P62942 FKB1A_HUMAN Homo sapiens 3 0.8182
Pteridine reductase O76290 O76290_TRYBB Trypanosoma brucei brucei 3 0.8182
Peptidyl-prolyl cis-trans isomerase FKBP1A P62942 FKB1A_HUMAN Homo sapiens 3 0.8182
Pteridine reductase O76290 O76290_TRYBB Trypanosoma brucei brucei 3 0.8182
Heat shock protein HSP 90-beta P08238 HS90B_HUMAN Homo sapiens 3 0.8171
Heat shock protein HSP 90-beta P08238 HS90B_HUMAN Homo sapiens 3 0.8171
IOMT 3 Q06YR3 Q06YR3_MEDTR Medicago truncatula 4 0.8169
IOMT 3 Q06YR3 Q06YR3_MEDTR Medicago truncatula 4 0.8169
Mitogen-activated protein kinase 14 Q16539 MK14_HUMAN Homo sapiens 3 0.8151
Mitogen-activated protein kinase 14 Q16539 MK14_HUMAN Homo sapiens 3 0.8151
Beta-glucuronidase P05804 BGLR_ECOLI Escherichia coli 3 0.8150
Beta-glucuronidase P05804 BGLR_ECOLI Escherichia coli 3 0.8150
Gag-Pol polyprotein P03367 POL_HV1BR Human immunodeficiency virus type 1 group M subtype B 3 0.8136
Gag-Pol polyprotein P03367 POL_HV1BR Human immunodeficiency virus type 1 group M subtype B 3 0.8136
Beta-secretase 1 P56817 BACE1_HUMAN Homo sapiens 3 0.8133
Beta-secretase 1 P56817 BACE1_HUMAN Homo sapiens 3 0.8133
Prenyltransferase Q4R2T2 Q4R2T2_STRC1 Streptomyces sp 3 0.8130
Prenyltransferase Q4R2T2 Q4R2T2_STRC1 Streptomyces sp 3 0.8130
Glycogen synthase kinase-3 beta P49841 GSK3B_HUMAN Homo sapiens 3 0.8105
Glycogen synthase kinase-3 beta P49841 GSK3B_HUMAN Homo sapiens 3 0.8105
Gag-Pol polyprotein P12497 POL_HV1N5 Human immunodeficiency virus type 1 group M subtype B 3 0.8099
Gag-Pol polyprotein P12497 POL_HV1N5 Human immunodeficiency virus type 1 group M subtype B 3 0.8099
Peptidyl-prolyl cis-trans isomerase FKBP1A P62942 FKB1A_HUMAN Homo sapiens 3 0.8098
Peptidyl-prolyl cis-trans isomerase FKBP1A P62942 FKB1A_HUMAN Homo sapiens 3 0.8098
Mycocyclosin synthase P9WPP7 CP121_MYCTU Mycobacterium tuberculosis 3 0.8091
Mycocyclosin synthase P9WPP7 CP121_MYCTU Mycobacterium tuberculosis 3 0.8091
Nucleoside diphosphate kinase A 2 P52175 NDKA2_BOVIN Bos taurus 4 0.8088
Nucleoside diphosphate kinase A 2 P52175 NDKA2_BOVIN Bos taurus 4 0.8088
3-ketosteroid dehydrogenase Q9RA02 Q9RA02_RHOER Rhodococcus erythropolis 3 0.8082
3-ketosteroid dehydrogenase Q9RA02 Q9RA02_RHOER Rhodococcus erythropolis 3 0.8082
Homoserine dehydrogenase P31116 DHOM_YEAST Saccharomyces cerevisiae 4 0.8078
Homoserine dehydrogenase P31116 DHOM_YEAST Saccharomyces cerevisiae 4 0.8078
Heat shock protein HSP 90-alpha P07900 HS90A_HUMAN Homo sapiens 3 0.8077
Heat shock protein HSP 90-alpha P07900 HS90A_HUMAN Homo sapiens 3 0.8077
3',5'-cyclic-AMP phosphodiesterase 4D Q08499 PDE4D_HUMAN Homo sapiens 3 0.8072
3',5'-cyclic-AMP phosphodiesterase 4D Q08499 PDE4D_HUMAN Homo sapiens 3 0.8072
Steroid C26-monooxygenase P9WPP1 CP125_MYCTU Mycobacterium tuberculosis 3 0.8071
Steroid C26-monooxygenase P9WPP1 CP125_MYCTU Mycobacterium tuberculosis 3 0.8071
Gastrotropin P51161 FABP6_HUMAN Homo sapiens 3 0.8066
Gastrotropin P51161 FABP6_HUMAN Homo sapiens 3 0.8066
cAMP-dependent protein kinase catalytic subunit alpha P00517 KAPCA_BOVIN Bos taurus 3 0.8061
cAMP-dependent protein kinase catalytic subunit alpha P00517 KAPCA_BOVIN Bos taurus 3 0.8061
Steroid Delta-isomerase P00947 SDIS_COMTE Comamonas testosteroni 3 0.8051
Steroid Delta-isomerase P00947 SDIS_COMTE Comamonas testosteroni 3 0.8051
Serine/threonine-protein kinase 24 Q9Y6E0 STK24_HUMAN Homo sapiens 3 0.8044
Serine/threonine-protein kinase 24 Q9Y6E0 STK24_HUMAN Homo sapiens 3 0.8044
Mitogen-activated protein kinase 14 Q16539 MK14_HUMAN Homo sapiens 3 0.8036
DNA gyrase subunit A P0AES5 GYRA_SHIFL Shigella flexneri 3 0.8036
Mitogen-activated protein kinase 14 Q16539 MK14_HUMAN Homo sapiens 3 0.8036
DNA gyrase subunit A P0AES5 GYRA_SHIFL Shigella flexneri 3 0.8036
GCN5-related N-acetyltransferase B1YEL6 B1YEL6_EXIS2 Exiguobacterium sibiricum 3 0.8031
GCN5-related N-acetyltransferase B1YEL6 B1YEL6_EXIS2 Exiguobacterium sibiricum 3 0.8031
11-beta-hydroxysteroid dehydrogenase 1 P28845 DHI1_HUMAN Homo sapiens 3 0.8008
11-beta-hydroxysteroid dehydrogenase 1 P28845 DHI1_HUMAN Homo sapiens 3 0.8008
ATP-dependent molecular chaperone HSP82 P02829 HSP82_YEAST Saccharomyces cerevisiae 3 0.8001
ATP-dependent molecular chaperone HSP82 P02829 HSP82_YEAST Saccharomyces cerevisiae 3 0.8001
GCN5-related N-acetyltransferase B1YEL6 B1YEL6_EXIS2 Exiguobacterium sibiricum 3 0.8001
GCN5-related N-acetyltransferase B1YEL6 B1YEL6_EXIS2 Exiguobacterium sibiricum 3 0.8001
Cyclin-dependent kinase 8 P49336 CDK8_HUMAN Homo sapiens 3 0.7997
Cyclin-dependent kinase 8 P49336 CDK8_HUMAN Homo sapiens 3 0.7997
Mitogen-activated protein kinase 14 Q16539 MK14_HUMAN Homo sapiens 3 0.7988
Mitogen-activated protein kinase 14 Q16539 MK14_HUMAN Homo sapiens 3 0.7988
Lactoperoxidase A0A452E9Y6 PERL_CAPHI Capra hircus 3 0.7977
Lactoperoxidase A0A452E9Y6 PERL_CAPHI Capra hircus 3 0.7977
Mycocyclosin synthase P9WPP7 CP121_MYCTU Mycobacterium tuberculosis 3 0.7964
Mycocyclosin synthase P9WPP7 CP121_MYCTU Mycobacterium tuberculosis 3 0.7964
HTH-type transcriptional regulator TtgR Q9AIU0 TTGR_PSEPT Pseudomonas putida 3 0.7948
HTH-type transcriptional regulator TtgR Q9AIU0 TTGR_PSEPT Pseudomonas putida 3 0.7948
ADP-ribosylation factor 1 P84077 ARF1_HUMAN Homo sapiens 2 0.7945
ADP-ribosylation factor 1 P84077 ARF1_HUMAN Homo sapiens 2 0.7945
Kinesin-like protein KIF11 P52732 KIF11_HUMAN Homo sapiens 3 0.7942
Kinesin-like protein KIF11 P52732 KIF11_HUMAN Homo sapiens 3 0.7942
Heat shock protein HSP 90-alpha P07900 HS90A_HUMAN Homo sapiens 3 0.7929
Heat shock protein HSP 90-alpha P07900 HS90A_HUMAN Homo sapiens 3 0.7929
Purine nucleoside phosphorylase P00491 PNPH_HUMAN Homo sapiens 3 0.7916
Purine nucleoside phosphorylase P00491 PNPH_HUMAN Homo sapiens 3 0.7916
Basic phospholipase A2 VRV-PL-VIIIa P59071 PA2B8_DABRR Daboia russelii 2 0.7910
Basic phospholipase A2 VRV-PL-VIIIa P59071 PA2B8_DABRR Daboia russelii 2 0.7910
Vascular endothelial growth factor receptor 2 P35968 VGFR2_HUMAN Homo sapiens 3 0.7908
Vascular endothelial growth factor receptor 2 P35968 VGFR2_HUMAN Homo sapiens 3 0.7908
Matrilysin P09237 MMP7_HUMAN Homo sapiens 3 0.7904
Matrilysin P09237 MMP7_HUMAN Homo sapiens 3 0.7904
Cytohesin-2 Q99418 CYH2_HUMAN Homo sapiens 3 0.7897
Cytohesin-2 Q99418 CYH2_HUMAN Homo sapiens 3 0.7897
Dihydrofolate reductase P22906 DYR_CANAX Candida albicans 3 0.7895
Dihydrofolate reductase P22906 DYR_CANAX Candida albicans 3 0.7895
TamL D3Y1I2 D3Y1I2_9ACTN Streptomyces sp. 307-9 3 0.7892
TamL D3Y1I2 D3Y1I2_9ACTN Streptomyces sp. 307-9 3 0.7892
Serine/threonine-protein kinase pim-1 P11309 PIM1_HUMAN Homo sapiens 3 0.7891
Serine/threonine-protein kinase pim-1 P11309 PIM1_HUMAN Homo sapiens 3 0.7891
Dihydrofolate reductase P22906 DYR_CANAX Candida albicans 3 0.7890
Dihydrofolate reductase P22906 DYR_CANAX Candida albicans 3 0.7890
Kinesin-like protein KIF11 P52732 KIF11_HUMAN Homo sapiens 3 0.7885
Kinesin-like protein KIF11 P52732 KIF11_HUMAN Homo sapiens 3 0.7885
17beta-hydroxysteroid dehydrogenase O93874 O93874_COCLU Cochliobolus lunatus 3 0.7876
17beta-hydroxysteroid dehydrogenase O93874 O93874_COCLU Cochliobolus lunatus 3 0.7876
Heat shock protein HSP 90-alpha P07900 HS90A_HUMAN Homo sapiens 3 0.7856
Heat shock protein HSP 90-alpha P07900 HS90A_HUMAN Homo sapiens 3 0.7856
Endothiapepsin P11838 CARP_CRYPA Cryphonectria parasitica 3 0.7852
Endothiapepsin P11838 CARP_CRYPA Cryphonectria parasitica 3 0.7852
Pyridoxal kinase P82197 PDXK_SHEEP Ovis aries 3 0.7851
Pyridoxal kinase P82197 PDXK_SHEEP Ovis aries 3 0.7851
17beta-hydroxysteroid dehydrogenase O93874 O93874_COCLU Cochliobolus lunatus 3 0.7844
17beta-hydroxysteroid dehydrogenase O93874 O93874_COCLU Cochliobolus lunatus 3 0.7844
Cytochrome P450 130 P9WPN5 CP130_MYCTU Mycobacterium tuberculosis 3 0.7832
tyrosine--tRNA ligase Q4QFJ7 Q4QFJ7_LEIMA Leishmania major 3 0.7832
Cytochrome P450 130 P9WPN5 CP130_MYCTU Mycobacterium tuberculosis 3 0.7832
tyrosine--tRNA ligase Q4QFJ7 Q4QFJ7_LEIMA Leishmania major 3 0.7832
Multidrug transporter MdfA P0AEY8 MDFA_ECOLI Escherichia coli 3 0.7831
Multidrug transporter MdfA P0AEY8 MDFA_ECOLI Escherichia coli 3 0.7831
Serine/threonine-protein kinase pim-1 P11309 PIM1_HUMAN Homo sapiens 3 0.7827
Serine/threonine-protein kinase pim-1 P11309 PIM1_HUMAN Homo sapiens 3 0.7827
Poly [ADP-ribose] polymerase tankyrase-2 Q9H2K2 TNKS2_HUMAN Homo sapiens 3 0.7815
Poly [ADP-ribose] polymerase tankyrase-2 Q9H2K2 TNKS2_HUMAN Homo sapiens 3 0.7815
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A Q9Y233 PDE10_HUMAN Homo sapiens 3 0.7811
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A Q9Y233 PDE10_HUMAN Homo sapiens 3 0.7811
ALK tyrosine kinase receptor Q9UM73 ALK_HUMAN Homo sapiens 3 0.7805
ALK tyrosine kinase receptor Q9UM73 ALK_HUMAN Homo sapiens 3 0.7805
Caspase-3 P42574 CASP3_HUMAN Homo sapiens 3 0.7803
Caspase-3 P42574 CASP3_HUMAN Homo sapiens 3 0.7803
Calmodulin-like domain protein kinase isoenzyme gamma, related F0V9W9 F0V9W9_NEOCL Neospora caninum 3 0.7782
Calmodulin-like domain protein kinase isoenzyme gamma, related F0V9W9 F0V9W9_NEOCL Neospora caninum 3 0.7782
Cyclin-dependent kinase 2 P24941 CDK2_HUMAN Homo sapiens 3 0.7780
Cyclin-dependent kinase 2 P24941 CDK2_HUMAN Homo sapiens 3 0.7780
Histone deacetylase 4 P56524 HDAC4_HUMAN Homo sapiens 2 0.7778
Histone deacetylase 4 P56524 HDAC4_HUMAN Homo sapiens 2 0.7778
HTH-type transcriptional repressor PurR P0ACP7 PURR_ECOLI Escherichia coli 3 0.7775
HTH-type transcriptional repressor PurR P0ACP7 PURR_ECOLI Escherichia coli 3 0.7775
Gag-Pol polyprotein P04584 POL_HV2RO Human immunodeficiency virus type 2 subtype A 3 0.7772
Thymidylate synthase P00469 TYSY_LACCA Lacticaseibacillus casei 3 0.7772
Thymidylate synthase P00469 TYSY_LACCA Lacticaseibacillus casei 3 0.7772
Gag-Pol polyprotein P04584 POL_HV2RO Human immunodeficiency virus type 2 subtype A 3 0.7772
Protein ppBat Q8A8A4 Q8A8A4_BACTN Bacteroides thetaiotaomicron VPI-5482 3 0.7769
Protein ppBat Q8A8A4 Q8A8A4_BACTN Bacteroides thetaiotaomicron VPI-5482 3 0.7769
ALK tyrosine kinase receptor Q9UM73 ALK_HUMAN Homo sapiens 3 0.7758
Activin receptor type-1 Q04771 ACVR1_HUMAN Homo sapiens 3 0.7758
Activin receptor type-1 Q04771 ACVR1_HUMAN Homo sapiens 3 0.7758
ALK tyrosine kinase receptor Q9UM73 ALK_HUMAN Homo sapiens 3 0.7758
Transthyretin P02767 TTHY_RAT Rattus norvegicus 3 0.7757
Transthyretin P02767 TTHY_RAT Rattus norvegicus 3 0.7757
Beta-secretase 1 P56817 BACE1_HUMAN Homo sapiens 3 0.7754
Beta-secretase 1 P56817 BACE1_HUMAN Homo sapiens 3 0.7754
Genome polyprotein P26663 POLG_HCVBK Hepatitis C virus genotype 1b 3 0.7751
Genome polyprotein P26663 POLG_HCVBK Hepatitis C virus genotype 1b 3 0.7751
Pheromone-binding protein ASP1 Q9U9J6 Q9U9J6_APIME Apis mellifera 3 0.7748
Pheromone-binding protein ASP1 Q9U9J6 Q9U9J6_APIME Apis mellifera 3 0.7748
Ribosyldihydronicotinamide dehydrogenase [quinone] P16083 NQO2_HUMAN Homo sapiens 4 0.7747
Ribosyldihydronicotinamide dehydrogenase [quinone] P16083 NQO2_HUMAN Homo sapiens 4 0.7747
Polyribonucleotide nucleotidyltransferase A7ZS61 PNP_ECO24 Escherichia coli O139:H28 3 0.7742
Polyribonucleotide nucleotidyltransferase A7ZS61 PNP_ECO24 Escherichia coli O139:H28 3 0.7742
GTPase KRas P01116 RASK_HUMAN Homo sapiens 3 0.7735
GTPase KRas P01116 RASK_HUMAN Homo sapiens 3 0.7735
Serine/threonine-protein kinase Chk1 O14757 CHK1_HUMAN Homo sapiens 3 0.7729
Serine/threonine-protein kinase Chk1 O14757 CHK1_HUMAN Homo sapiens 3 0.7729
ALK tyrosine kinase receptor Q9UM73 ALK_HUMAN Homo sapiens 3 0.7728
cGMP-dependent protein kinase 1 Q13976 KGP1_HUMAN Homo sapiens 3 0.7728
cGMP-dependent protein kinase 1 Q13976 KGP1_HUMAN Homo sapiens 3 0.7728
ALK tyrosine kinase receptor Q9UM73 ALK_HUMAN Homo sapiens 3 0.7728
DNA gyrase subunit B Q839Z1 GYRB_ENTFA Enterococcus faecalis 3 0.7728
DNA gyrase subunit B Q839Z1 GYRB_ENTFA Enterococcus faecalis 3 0.7728
Beta-lactamase Q9L5C8 Q9L5C8_ECOLX Escherichia coli 3 0.7721
Beta-lactamase Q9L5C8 Q9L5C8_ECOLX Escherichia coli 3 0.7721
Urokinase-type plasminogen activator P00749 UROK_HUMAN Homo sapiens 3 0.7715
Urokinase-type plasminogen activator P00749 UROK_HUMAN Homo sapiens 3 0.7715
Glycogen synthase kinase-3 beta P49841 GSK3B_HUMAN Homo sapiens 3 0.7712
Glycogen synthase kinase-3 beta P49841 GSK3B_HUMAN Homo sapiens 3 0.7712
ATP synthase subunit alpha, mitochondrial P19483 ATPA_BOVIN Bos taurus 4 0.7709
ATP synthase subunit alpha, mitochondrial P19483 ATPA_BOVIN Bos taurus 4 0.7709
Probable nicotinate-nucleotide adenylyltransferase Q9HX21 NADD_PSEAE Pseudomonas aeruginosa 3 0.7708
Probable nicotinate-nucleotide adenylyltransferase Q9HX21 NADD_PSEAE Pseudomonas aeruginosa 3 0.7708
Chalcone--flavanone isomerase 1 P28012 CFI1_MEDSA Medicago sativa 3 0.7702
Chalcone--flavanone isomerase 1 P28012 CFI1_MEDSA Medicago sativa 3 0.7702
Annexin A5 P08758 ANXA5_HUMAN Homo sapiens 2 0.7701
Annexin A5 P08758 ANXA5_HUMAN Homo sapiens 2 0.7701
Gag-Pol polyprotein P03367 POL_HV1BR Human immunodeficiency virus type 1 group M subtype B 3 0.7696
Gag-Pol polyprotein P03367 POL_HV1BR Human immunodeficiency virus type 1 group M subtype B 3 0.7696
Pol protein Q000H7 Q000H7_9HIV1 Human immunodeficiency virus 1 3 0.7694
Pol protein Q000H7 Q000H7_9HIV1 Human immunodeficiency virus 1 3 0.7694
Mycinamicin III 3''-O-methyltransferase Q49492 MYCF_MICGR Micromonospora griseorubida 2 0.7687
Mycinamicin III 3''-O-methyltransferase Q49492 MYCF_MICGR Micromonospora griseorubida 2 0.7687
Epidermal growth factor receptor P00533 EGFR_HUMAN Homo sapiens 3 0.7683
Epidermal growth factor receptor P00533 EGFR_HUMAN Homo sapiens 3 0.7683
Class B acid phosphatase Q540U1 APHA_SALTM Salmonella typhimurium 3 0.7678
Class B acid phosphatase Q540U1 APHA_SALTM Salmonella typhimurium 3 0.7678
ALK tyrosine kinase receptor Q9UM73 ALK_HUMAN Homo sapiens 3 0.7676
ALK tyrosine kinase receptor Q9UM73 ALK_HUMAN Homo sapiens 3 0.7676
ALK tyrosine kinase receptor Q9UM73 ALK_HUMAN Homo sapiens 3 0.7669
ALK tyrosine kinase receptor Q9UM73 ALK_HUMAN Homo sapiens 3 0.7669
Ephrin type-B receptor 4 P54760 EPHB4_HUMAN Homo sapiens 3 0.7668
Ephrin type-B receptor 4 P54760 EPHB4_HUMAN Homo sapiens 3 0.7668
HTH-type transcriptional repressor PurR P0ACP7 PURR_ECOLI Escherichia coli 3 0.7667
HTH-type transcriptional repressor PurR P0ACP7 PURR_ECOLI Escherichia coli 3 0.7667
Nuclear receptor subfamily 1 group I member 2 O75469 NR1I2_HUMAN Homo sapiens 3 0.7665
Nuclear receptor subfamily 1 group I member 2 O75469 NR1I2_HUMAN Homo sapiens 3 0.7665
Protoporphyrinogen oxidase P50336 PPOX_HUMAN Homo sapiens 3 0.7662
Protoporphyrinogen oxidase P50336 PPOX_HUMAN Homo sapiens 3 0.7662
Basic phospholipase A2 VRV-PL-VIIIa P59071 PA2B8_DABRR Daboia russelii 3 0.7645
Tyrosine-protein kinase HCK P08631 HCK_HUMAN Homo sapiens 3 0.7645
Tyrosine-protein kinase HCK P08631 HCK_HUMAN Homo sapiens 3 0.7645
Basic phospholipase A2 VRV-PL-VIIIa P59071 PA2B8_DABRR Daboia russelii 3 0.7645
Basic phospholipase A2 VRV-PL-VIIIa P59071 PA2B8_DABRR Daboia russelii 2 0.7642
Basic phospholipase A2 VRV-PL-VIIIa P59071 PA2B8_DABRR Daboia russelii 2 0.7642
Proto-oncogene tyrosine-protein kinase Src P00523 SRC_CHICK Gallus gallus 2 0.7640
Proto-oncogene tyrosine-protein kinase Src P00523 SRC_CHICK Gallus gallus 2 0.7640
ALK tyrosine kinase receptor Q9UM73 ALK_HUMAN Homo sapiens 3 0.7630
ALK tyrosine kinase receptor Q9UM73 ALK_HUMAN Homo sapiens 3 0.7630
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial Q15119 PDK2_HUMAN Homo sapiens 3 0.7629
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial Q15119 PDK2_HUMAN Homo sapiens 3 0.7629
Endoplasmic reticulum aminopeptidase 2 Q6P179 ERAP2_HUMAN Homo sapiens 2 0.7625
Endoplasmic reticulum aminopeptidase 2 Q6P179 ERAP2_HUMAN Homo sapiens 2 0.7625
Aldo-keto reductase family 1 member B1 P15121 ALDR_HUMAN Homo sapiens 3 0.7623
Aldo-keto reductase family 1 member B1 P15121 ALDR_HUMAN Homo sapiens 3 0.7623
Genome polyprotein C0LMU0 C0LMU0_9FLAV dengue virus type 3 3 0.7621
Genome polyprotein C0LMU0 C0LMU0_9FLAV dengue virus type 3 3 0.7621
Purine nucleoside phosphorylase DeoD-type P0ABP9 DEOD_ECO57 Escherichia coli O157:H7 3 0.7619
Purine nucleoside phosphorylase DeoD-type P0ABP9 DEOD_ECO57 Escherichia coli O157:H7 3 0.7619
Seminal ribonuclease P00669 RNS_BOVIN Bos taurus 3 0.7618
Seminal ribonuclease P00669 RNS_BOVIN Bos taurus 3 0.7618
Adenylate cyclase type 5 P30803 ADCY5_CANLF Canis lupus familiaris 4 0.7614
Adenylate cyclase type 5 P30803 ADCY5_CANLF Canis lupus familiaris 4 0.7614
Dihydrofolate reductase P0ABQ4 DYR_ECOLI Escherichia coli 3 0.7612
Dihydrofolate reductase P0ABQ4 DYR_ECOLI Escherichia coli 3 0.7612
Serine/threonine-protein kinase pim-1 P11309 PIM1_HUMAN Homo sapiens 3 0.7612
Serine/threonine-protein kinase pim-1 P11309 PIM1_HUMAN Homo sapiens 3 0.7612
Beta-secretase 1 P56817 BACE1_HUMAN Homo sapiens 2 0.7608
Beta-secretase 1 P56817 BACE1_HUMAN Homo sapiens 2 0.7608
Adenylate cyclase type 5 P30803 ADCY5_CANLF Canis lupus familiaris 4 0.7605
Adenylate cyclase type 5 P30803 ADCY5_CANLF Canis lupus familiaris 4 0.7605
HTH-type transcriptional repressor PurR P0ACP7 PURR_ECOLI Escherichia coli 3 0.7604
HTH-type transcriptional repressor PurR P0ACP7 PURR_ECOLI Escherichia coli 3 0.7604
Aldehyde dehydrogenase, mitochondrial P05091 ALDH2_HUMAN Homo sapiens 3 0.7602
Aldehyde dehydrogenase, mitochondrial P05091 ALDH2_HUMAN Homo sapiens 3 0.7602
cAMP-dependent protein kinase catalytic subunit alpha P00517 KAPCA_BOVIN Bos taurus 3 0.7601
cAMP-dependent protein kinase catalytic subunit alpha P00517 KAPCA_BOVIN Bos taurus 3 0.7601
Phosphatidylinositol 5-phosphate 4-kinase type-2 beta P78356 PI42B_HUMAN Homo sapiens 3 0.7597
Phosphatidylinositol 5-phosphate 4-kinase type-2 beta P78356 PI42B_HUMAN Homo sapiens 3 0.7597
Tau-tubulin kinase 1 Q5TCY1 TTBK1_HUMAN Homo sapiens 3 0.7595
Tau-tubulin kinase 1 Q5TCY1 TTBK1_HUMAN Homo sapiens 3 0.7595
Nickel-binding periplasmic protein P33590 NIKA_ECOLI Escherichia coli 2 0.7593
Nickel-binding periplasmic protein P33590 NIKA_ECOLI Escherichia coli 2 0.7593
Macrophage colony-stimulating factor 1 receptor P07333 CSF1R_HUMAN Homo sapiens 3 0.7591
Macrophage colony-stimulating factor 1 receptor P07333 CSF1R_HUMAN Homo sapiens 3 0.7591
Actin-related protein 3 P61157 ARP3_BOVIN Bos taurus 3 0.7591
Actin-related protein 3 P61157 ARP3_BOVIN Bos taurus 3 0.7591
Nitric oxide synthase, inducible P29477 NOS2_MOUSE Mus musculus 3 0.7587
Nitric oxide synthase, inducible P29477 NOS2_MOUSE Mus musculus 3 0.7587
Thymidylate synthase P00469 TYSY_LACCA Lacticaseibacillus casei 2 0.7582
Thymidylate synthase P00469 TYSY_LACCA Lacticaseibacillus casei 2 0.7582
Serine/threonine-protein kinase Chk1 O14757 CHK1_HUMAN Homo sapiens 3 0.7581
Serine/threonine-protein kinase Chk1 O14757 CHK1_HUMAN Homo sapiens 3 0.7581
tRNA (adenine(9)-N1)-methyltransferase Q4J894 TRM10_SULAC Sulfolobus acidocaldarius 3 0.7580
tRNA (adenine(9)-N1)-methyltransferase Q4J894 TRM10_SULAC Sulfolobus acidocaldarius 3 0.7580
Beta-secretase 1 P56817 BACE1_HUMAN Homo sapiens 2 0.7579
Beta-secretase 1 P56817 BACE1_HUMAN Homo sapiens 2 0.7579
Beta-secretase 1 P56817 BACE1_HUMAN Homo sapiens 2 0.7578
Beta-secretase 1 P56817 BACE1_HUMAN Homo sapiens 2 0.7578
Carbonic anhydrase 2 P00918 CAH2_HUMAN Homo sapiens 2 0.7575
Carbonic anhydrase 2 P00918 CAH2_HUMAN Homo sapiens 2 0.7575
Beta-lactamase Q9L5C8 Q9L5C8_ECOLX Escherichia coli 3 0.7573
Beta-lactamase Q9L5C8 Q9L5C8_ECOLX Escherichia coli 3 0.7573
Death-associated protein kinase 1 P53355 DAPK1_HUMAN Homo sapiens 4 0.7572
Death-associated protein kinase 1 P53355 DAPK1_HUMAN Homo sapiens 4 0.7572
Vitamin D3 dihydroxylase P18326 CPXE_STRGO Streptomyces griseolus 3 0.7569
Vitamin D3 dihydroxylase P18326 CPXE_STRGO Streptomyces griseolus 3 0.7569
Nickel-binding periplasmic protein P33590 NIKA_ECOLI Escherichia coli 2 0.7568
Nickel-binding periplasmic protein P33590 NIKA_ECOLI Escherichia coli 2 0.7568
Carbonic anhydrase 2 P00918 CAH2_HUMAN Homo sapiens 3 0.7566
Carbonic anhydrase 2 P00918 CAH2_HUMAN Homo sapiens 3 0.7566
Adenylate cyclase type 5 P30803 ADCY5_CANLF Canis lupus familiaris 4 0.7557
Adenylate cyclase type 5 P30803 ADCY5_CANLF Canis lupus familiaris 4 0.7557
Gag-Pol polyprotein P03367 POL_HV1BR Human immunodeficiency virus type 1 group M subtype B 3 0.7553
Gag-Pol polyprotein P03367 POL_HV1BR Human immunodeficiency virus type 1 group M subtype B 3 0.7553
cGMP-dependent protein kinase 2 Q13237 KGP2_HUMAN Homo sapiens 3 0.7550
cGMP-dependent protein kinase 2 Q13237 KGP2_HUMAN Homo sapiens 3 0.7550
Methionine aminopeptidase 2 P50579 MAP2_HUMAN Homo sapiens 3 0.7545
Casein kinase II subunit alpha P68400 CSK21_HUMAN Homo sapiens 3 0.7545
Casein kinase II subunit alpha P68400 CSK21_HUMAN Homo sapiens 3 0.7545
Methionine aminopeptidase 2 P50579 MAP2_HUMAN Homo sapiens 3 0.7545
11-beta-hydroxysteroid dehydrogenase 1 P28845 DHI1_HUMAN Homo sapiens 3 0.7541
11-beta-hydroxysteroid dehydrogenase 1 P28845 DHI1_HUMAN Homo sapiens 3 0.7541
Serine/threonine-protein kinase Chk1 O14757 CHK1_HUMAN Homo sapiens 3 0.7539
Serine/threonine-protein kinase Chk1 O14757 CHK1_HUMAN Homo sapiens 3 0.7539
Riboflavin synthase P0AFU8 RISA_ECOLI Escherichia coli 3 0.7539
Riboflavin synthase P0AFU8 RISA_ECOLI Escherichia coli 3 0.7539
Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial Q33862 Q33862_ASCSU Ascaris suum 2 0.7531
Cyclin-dependent kinase 9 P50750 CDK9_HUMAN Homo sapiens 3 0.7531
Cyclin-dependent kinase 9 P50750 CDK9_HUMAN Homo sapiens 3 0.7531
Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial Q33862 Q33862_ASCSU Ascaris suum 2 0.7531
Soluble acetylcholine receptor Q8WSF8 Q8WSF8_APLCA Aplysia californica 3 0.7530
Soluble acetylcholine receptor Q8WSF8 Q8WSF8_APLCA Aplysia californica 3 0.7530
Proto-oncogene tyrosine-protein kinase receptor Ret P07949 RET_HUMAN Homo sapiens 3 0.7524
Proto-oncogene tyrosine-protein kinase receptor Ret P07949 RET_HUMAN Homo sapiens 3 0.7524
Cyclin-dependent kinase 9 P50750 CDK9_HUMAN Homo sapiens 3 0.7521
Cyclin-dependent kinase 9 P50750 CDK9_HUMAN Homo sapiens 3 0.7521
Probable esterase KAI2 Q9SZU7 KAI2_ARATH Arabidopsis thaliana 3 0.7519
Probable esterase KAI2 Q9SZU7 KAI2_ARATH Arabidopsis thaliana 3 0.7519
Heat shock protein HSP 90-alpha P07900 HS90A_HUMAN Homo sapiens 3 0.7505
Heat shock protein HSP 90-alpha P07900 HS90A_HUMAN Homo sapiens 3 0.7505
Genome polyprotein P26663 POLG_HCVBK Hepatitis C virus genotype 1b 3 0.7504
Protein S100-A13 Q99584 S10AD_HUMAN Homo sapiens 3 0.7504
Genome polyprotein P26663 POLG_HCVBK Hepatitis C virus genotype 1b 3 0.7504
Protein S100-A13 Q99584 S10AD_HUMAN Homo sapiens 3 0.7504
Bromodomain-containing protein 2 P25440 BRD2_HUMAN Homo sapiens 3 0.7499
Bromodomain-containing protein 2 P25440 BRD2_HUMAN Homo sapiens 3 0.7499
Urokinase-type plasminogen activator P00749 UROK_HUMAN Homo sapiens 2 0.7492
Urokinase-type plasminogen activator P00749 UROK_HUMAN Homo sapiens 2 0.7492
Class 10 plant pathogenesis-related protein 2B Q9LLQ2 P102B_LUPLU Lupinus luteus 2 0.7487
Class 10 plant pathogenesis-related protein 2B Q9LLQ2 P102B_LUPLU Lupinus luteus 2 0.7487
CREB-binding protein Q92793 CBP_HUMAN Homo sapiens 3 0.7486
CREB-binding protein Q92793 CBP_HUMAN Homo sapiens 3 0.7486
4-hydroxyphenylacetate 3-monooxygenase, reductase component Q5SJP7 HPAC_THET8 Thermus thermophilus 3 0.7484
4-hydroxyphenylacetate 3-monooxygenase, reductase component Q5SJP7 HPAC_THET8 Thermus thermophilus 3 0.7484
Cyclin-dependent kinase 2 P24941 CDK2_HUMAN Homo sapiens 3 0.7483
Cyclin-dependent kinase 2 P24941 CDK2_HUMAN Homo sapiens 3 0.7483
Bifunctional dihydrofolate reductase-thymidylate synthase P13922 DRTS_PLAFK Plasmodium falciparum 2 0.7479
Bifunctional dihydrofolate reductase-thymidylate synthase P13922 DRTS_PLAFK Plasmodium falciparum 2 0.7479
Actin-related protein 3 P61157 ARP3_BOVIN Bos taurus 3 0.7476
Actin-related protein 3 P61157 ARP3_BOVIN Bos taurus 3 0.7476
Serine/threonine-protein kinase Chk1 O14757 CHK1_HUMAN Homo sapiens 3 0.7474
Serine/threonine-protein kinase Chk1 O14757 CHK1_HUMAN Homo sapiens 3 0.7474
Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase Q05603 COBT_SALTY Salmonella typhimurium 3 0.7473
Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase Q05603 COBT_SALTY Salmonella typhimurium 3 0.7473
Gag-Pol polyprotein P12497 POL_HV1N5 Human immunodeficiency virus type 1 group M subtype B 2 0.7471
Gag-Pol polyprotein P12497 POL_HV1N5 Human immunodeficiency virus type 1 group M subtype B 2 0.7471
Leucoanthocyanidin dioxygenase Q96323 LDOX_ARATH Arabidopsis thaliana 4 0.7461
Leucoanthocyanidin dioxygenase Q96323 LDOX_ARATH Arabidopsis thaliana 4 0.7461
Genome polyprotein P26663 POLG_HCVBK Hepatitis C virus genotype 1b 2 0.7459
Genome polyprotein P26663 POLG_HCVBK Hepatitis C virus genotype 1b 2 0.7459
Endoplasmin P41148 ENPL_CANLF Canis lupus familiaris 3 0.7453
Endoplasmin P41148 ENPL_CANLF Canis lupus familiaris 3 0.7453
cAMP-dependent protein kinase catalytic subunit alpha P00517 KAPCA_BOVIN Bos taurus 3 0.7452
cAMP-dependent protein kinase catalytic subunit alpha P00517 KAPCA_BOVIN Bos taurus 3 0.7452
Pteridine reductase 1 Q01782 PTR1_LEIMA Leishmania major 3 0.7443
Pteridine reductase 1 Q01782 PTR1_LEIMA Leishmania major 3 0.7443
Orotidine 5'-phosphate decarboxylase O58462 PYRF_PYRHO Pyrococcus horikoshii 3 0.7442
Orotidine 5'-phosphate decarboxylase O58462 PYRF_PYRHO Pyrococcus horikoshii 3 0.7442
Serine/threonine-protein kinase Chk1 O14757 CHK1_HUMAN Homo sapiens 3 0.7438
Serine/threonine-protein kinase Chk1 O14757 CHK1_HUMAN Homo sapiens 3 0.7438
Bifunctional dihydrofolate reductase-thymidylate synthase Q27793 DRTS_TRYCR Trypanosoma cruzi 3 0.7437
Bifunctional dihydrofolate reductase-thymidylate synthase Q27793 DRTS_TRYCR Trypanosoma cruzi 3 0.7437
HTH-type transcriptional regulator TtgR Q9AIU0 TTGR_PSEPT Pseudomonas putida 3 0.7436
HTH-type transcriptional regulator TtgR Q9AIU0 TTGR_PSEPT Pseudomonas putida 3 0.7436
Glucan 1,3-beta-glucosidase P29717 EXG1_CANAL Candida albicans 2 0.7433
Glucan 1,3-beta-glucosidase P29717 EXG1_CANAL Candida albicans 2 0.7433
Heat shock protein HSP 90-alpha P07900 HS90A_HUMAN Homo sapiens 3 0.7430
Heat shock protein HSP 90-alpha P07900 HS90A_HUMAN Homo sapiens 3 0.7430
Purine nucleoside phosphorylase DeoD-type P0ABP9 DEOD_ECO57 Escherichia coli O157:H7 3 0.7426
Purine nucleoside phosphorylase DeoD-type P0ABP9 DEOD_ECO57 Escherichia coli O157:H7 3 0.7426
Coagulation factor X P00742 FA10_HUMAN Homo sapiens 3 0.7424
Coagulation factor X P00742 FA10_HUMAN Homo sapiens 3 0.7424
Interstitial collagenase P03956 MMP1_HUMAN Homo sapiens 3 0.7423
cAMP-dependent protein kinase type I-alpha regulatory subunit P00514 KAP0_BOVIN Bos taurus 2 0.7423
Interstitial collagenase P03956 MMP1_HUMAN Homo sapiens 3 0.7423
cAMP-dependent protein kinase type I-alpha regulatory subunit P00514 KAP0_BOVIN Bos taurus 2 0.7423
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A Q9Y233 PDE10_HUMAN Homo sapiens 3 0.7420
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A Q9Y233 PDE10_HUMAN Homo sapiens 3 0.7420
Cyclin-dependent kinase 2 P24941 CDK2_HUMAN Homo sapiens 3 0.7419
Polymerase basic protein 2 Q2LG68 Q2LG68_9INFA Influenza A virus) 4 0.7419
Polymerase basic protein 2 Q2LG68 Q2LG68_9INFA Influenza A virus) 4 0.7419
Cyclin-dependent kinase 2 P24941 CDK2_HUMAN Homo sapiens 3 0.7419
Probable flavin-dependent thymidylate synthase O41156 THYX_PBCV1 Paramecium bursaria Chlorella virus 1 3 0.7413
Probable flavin-dependent thymidylate synthase O41156 THYX_PBCV1 Paramecium bursaria Chlorella virus 1 3 0.7413
Heat shock protein HSP 90-alpha P07900 HS90A_HUMAN Homo sapiens 3 0.7409
Heat shock protein HSP 90-alpha P07900 HS90A_HUMAN Homo sapiens 3 0.7409
FMN-dependent NAD(P)H:quinone oxidoreductase 1 Q9I5F3 AZOR1_PSEAE Pseudomonas aeruginosa 2 0.7408
FMN-dependent NAD(P)H:quinone oxidoreductase 1 Q9I5F3 AZOR1_PSEAE Pseudomonas aeruginosa 2 0.7408
Carbonic anhydrase 2 P00918 CAH2_HUMAN Homo sapiens 2 0.7405
Carbonic anhydrase 2 P00918 CAH2_HUMAN Homo sapiens 2 0.7405
Dihydrofolate reductase P00374 DYR_HUMAN Homo sapiens 3 0.7403
Dihydrofolate reductase P00374 DYR_HUMAN Homo sapiens 3 0.7403
Uncharacterized protein Q3F0V8 Q3F0V8_BACTI Bacillus thuringiensis serovar israelensis ATCC 35646 3 0.7401
Uncharacterized protein Q3F0V8 Q3F0V8_BACTI Bacillus thuringiensis serovar israelensis ATCC 35646 3 0.7401
Aurora kinase A O14965 AURKA_HUMAN Homo sapiens 3 0.7397
Aurora kinase A O14965 AURKA_HUMAN Homo sapiens 3 0.7397
Glycogen synthase kinase-3 beta P49841 GSK3B_HUMAN Homo sapiens 2 0.7396
Glycogen synthase kinase-3 beta P49841 GSK3B_HUMAN Homo sapiens 2 0.7396
Nitric oxide synthase, inducible P29477 NOS2_MOUSE Mus musculus 3 0.7395
Nitric oxide synthase, inducible P29477 NOS2_MOUSE Mus musculus 3 0.7395
Mitochondrial poly(A) polymerase F1NBW0 F1NBW0_CHICK Gallus gallus 2 0.7392
Mitochondrial poly(A) polymerase F1NBW0 F1NBW0_CHICK Gallus gallus 2 0.7392
L-lactate dehydrogenase A chain P13491 LDHA_RABIT Oryctolagus cuniculus 2 0.7391
L-lactate dehydrogenase A chain P13491 LDHA_RABIT Oryctolagus cuniculus 2 0.7391
Nucleoside diphosphate kinase Q5UQL3 NDK_MIMIV Acanthamoeba polyphaga mimivirus 2 0.7389
Nucleoside diphosphate kinase Q5UQL3 NDK_MIMIV Acanthamoeba polyphaga mimivirus 2 0.7389
Cyclin-dependent kinase 2 P24941 CDK2_HUMAN Homo sapiens 3 0.7387
Cyclin-dependent kinase 2 P24941 CDK2_HUMAN Homo sapiens 3 0.7387
Metallo-beta-lactamase type 2 C7C422 BLAN1_KLEPN Klebsiella pneumoniae 2 0.7385
Metallo-beta-lactamase type 2 C7C422 BLAN1_KLEPN Klebsiella pneumoniae 2 0.7385
3-hydroxyanthranilate 3,4-dioxygenase Q1LCS4 3HAO_CUPMC Cupriavidus metallidurans 2 0.7377
3-hydroxyanthranilate 3,4-dioxygenase Q1LCS4 3HAO_CUPMC Cupriavidus metallidurans 2 0.7377
Basic phospholipase A2 VRV-PL-VIIIa P59071 PA2B8_DABRR Daboia russelii 2 0.7371
Basic phospholipase A2 VRV-PL-VIIIa P59071 PA2B8_DABRR Daboia russelii 2 0.7371
Stromelysin-1 P08254 MMP3_HUMAN Homo sapiens 3 0.7370
Stromelysin-1 P08254 MMP3_HUMAN Homo sapiens 3 0.7370
3-hydroxyisobutyryl-CoA hydrolase, mitochondrial Q6NVY1 HIBCH_HUMAN Homo sapiens 3 0.7363
3-hydroxyisobutyryl-CoA hydrolase, mitochondrial Q6NVY1 HIBCH_HUMAN Homo sapiens 3 0.7363
Mitogen-activated protein kinase 10 P53779 MK10_HUMAN Homo sapiens 3 0.7360
Mitogen-activated protein kinase 10 P53779 MK10_HUMAN Homo sapiens 3 0.7360
cGMP-dependent protein kinase 1 Q13976 KGP1_HUMAN Homo sapiens 3 0.7357
cGMP-dependent protein kinase 1 Q13976 KGP1_HUMAN Homo sapiens 3 0.7357
cGMP-dependent 3',5'-cyclic phosphodiesterase O00408 PDE2A_HUMAN Homo sapiens 3 0.7356
cGMP-dependent 3',5'-cyclic phosphodiesterase O00408 PDE2A_HUMAN Homo sapiens 3 0.7356
Serine/threonine-protein kinase Chk1 O14757 CHK1_HUMAN Homo sapiens 3 0.7355
Serine/threonine-protein kinase Chk1 O14757 CHK1_HUMAN Homo sapiens 3 0.7355
Casein kinase II subunit alpha P28523 CSK2A_MAIZE Zea mays 4 0.7354
Casein kinase II subunit alpha P28523 CSK2A_MAIZE Zea mays 4 0.7354
Mycocyclosin synthase P9WPP7 CP121_MYCTU Mycobacterium tuberculosis 3 0.7350
3',5'-cyclic-AMP phosphodiesterase 4D Q08499 PDE4D_HUMAN Homo sapiens 3 0.7350
3',5'-cyclic-AMP phosphodiesterase 4D Q08499 PDE4D_HUMAN Homo sapiens 3 0.7350
Adenylate cyclase type 5 P30803 ADCY5_CANLF Canis lupus familiaris 3 0.7350
Mycocyclosin synthase P9WPP7 CP121_MYCTU Mycobacterium tuberculosis 3 0.7350
Adenylate cyclase type 5 P30803 ADCY5_CANLF Canis lupus familiaris 3 0.7350
Proto-oncogene tyrosine-protein kinase Src P00523 SRC_CHICK Gallus gallus 3 0.7348
Proto-oncogene tyrosine-protein kinase Src P00523 SRC_CHICK Gallus gallus 3 0.7348
Myotonin-protein kinase Q09013 DMPK_HUMAN Homo sapiens 3 0.7344
Myotonin-protein kinase Q09013 DMPK_HUMAN Homo sapiens 3 0.7344
Cyclin-dependent kinase 2 P24941 CDK2_HUMAN Homo sapiens 3 0.7343
Cyclin-dependent kinase 2 P24941 CDK2_HUMAN Homo sapiens 3 0.7343
Cyclin-dependent kinase 2 P24941 CDK2_HUMAN Homo sapiens 3 0.7341
Carbonyl reductase [NADPH] 1 P16152 CBR1_HUMAN Homo sapiens 3 0.7341
Cyclin-dependent kinase 2 P24941 CDK2_HUMAN Homo sapiens 3 0.7341
Carbonyl reductase [NADPH] 1 P16152 CBR1_HUMAN Homo sapiens 3 0.7341
Mitogen-activated protein kinase 14 Q16539 MK14_HUMAN Homo sapiens 3 0.7338
Peroxisome proliferator-activated receptor gamma P37231 PPARG_HUMAN Homo sapiens 4 0.7338
Mitogen-activated protein kinase 14 Q16539 MK14_HUMAN Homo sapiens 3 0.7338
Peroxisome proliferator-activated receptor gamma P37231 PPARG_HUMAN Homo sapiens 4 0.7338
Soluble acetylcholine receptor Q8WSF8 Q8WSF8_APLCA Aplysia californica 2 0.7336
Soluble acetylcholine receptor Q8WSF8 Q8WSF8_APLCA Aplysia californica 2 0.7336
Mevalonate kinase P17256 KIME_RAT Rattus norvegicus 3 0.7331
17beta-hydroxysteroid dehydrogenase O93874 O93874_COCLU Cochliobolus lunatus 4 0.7331
Mevalonate kinase P17256 KIME_RAT Rattus norvegicus 3 0.7331
17beta-hydroxysteroid dehydrogenase O93874 O93874_COCLU Cochliobolus lunatus 4 0.7331
Aminotransferase homolog Q9S5Y7 Q9S5Y7_CAMJU Campylobacter jejuni 3 0.7330
Aminotransferase homolog Q9S5Y7 Q9S5Y7_CAMJU Campylobacter jejuni 3 0.7330
Pteridine reductase, putative Q581W1 Q581W1_TRYB2 Trypanosoma brucei brucei 3 0.7325
Pteridine reductase, putative Q581W1 Q581W1_TRYB2 Trypanosoma brucei brucei 3 0.7325
23S rRNA (guanine(745)-N(1))-methyltransferase P36999 RLMA_ECOLI Escherichia coli 4 0.7322
23S rRNA (guanine(745)-N(1))-methyltransferase P36999 RLMA_ECOLI Escherichia coli 4 0.7322
Bifunctional protein GlmU P43889 GLMU_HAEIN Haemophilus influenzae 2 0.7318
Bifunctional protein GlmU P43889 GLMU_HAEIN Haemophilus influenzae 2 0.7318
Purine nucleoside phosphorylase DeoD-type O34925 DEOD_BACSU Bacillus subtilis 2 0.7315
Purine nucleoside phosphorylase DeoD-type O34925 DEOD_BACSU Bacillus subtilis 2 0.7315
Multidrug efflux pump subunit AcrB P31224 ACRB_ECOLI Escherichia coli 3 0.7314
Multidrug efflux pump subunit AcrB P31224 ACRB_ECOLI Escherichia coli 3 0.7314
Flavoredoxin Q72HI0 Q72HI0_THET2 Thermus thermophilus 3 0.7312
Flavoredoxin Q72HI0 Q72HI0_THET2 Thermus thermophilus 3 0.7312
Serine/threonine-protein kinase Chk2 O96017 CHK2_HUMAN Homo sapiens 2 0.7310
Serine/threonine-protein kinase Chk2 O96017 CHK2_HUMAN Homo sapiens 2 0.7310
Adenylate cyclase type 5 P30803 ADCY5_CANLF Canis lupus familiaris 4 0.7308
Caspase-3 P42574 CASP3_HUMAN Homo sapiens 2 0.7308
Adenylate cyclase type 5 P30803 ADCY5_CANLF Canis lupus familiaris 4 0.7308
Caspase-3 P42574 CASP3_HUMAN Homo sapiens 2 0.7308
Gag-Pol polyprotein P12497 POL_HV1N5 Human immunodeficiency virus type 1 group M subtype B 2 0.7307
Gag-Pol polyprotein P12497 POL_HV1N5 Human immunodeficiency virus type 1 group M subtype B 2 0.7307
Serine/threonine-protein kinase SKY1 Q03656 SKY1_YEAST Saccharomyces cerevisiae 2 0.7306
Serine/threonine-protein kinase SKY1 Q03656 SKY1_YEAST Saccharomyces cerevisiae 2 0.7306
Endothiapepsin P11838 CARP_CRYPA Cryphonectria parasitica 2 0.7306
Endothiapepsin P11838 CARP_CRYPA Cryphonectria parasitica 2 0.7306
Phenylalanine-4-hydroxylase P00439 PH4H_HUMAN Homo sapiens 2 0.7303
Phenylalanine-4-hydroxylase P00439 PH4H_HUMAN Homo sapiens 2 0.7303
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform O02697 PK3CG_PIG Sus scrofa 4 0.7299
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform O02697 PK3CG_PIG Sus scrofa 4 0.7299
Rifampin ADP-ribosyl transferase A0QRS5 A0QRS5_MYCS2 Mycolicibacterium smegmatis155) 3 0.7294
Rifampin ADP-ribosyl transferase A0QRS5 A0QRS5_MYCS2 Mycolicibacterium smegmatis155) 3 0.7294
Glutamate receptor 2 P19491 GRIA2_RAT Rattus norvegicus 2 0.7294
Glutamate receptor 2 P19491 GRIA2_RAT Rattus norvegicus 2 0.7294
Endothiapepsin P11838 CARP_CRYPA Cryphonectria parasitica 2 0.7291
Endothiapepsin P11838 CARP_CRYPA Cryphonectria parasitica 2 0.7291
Pheromone-binding protein ASP1 Q9U9J6 Q9U9J6_APIME Apis mellifera 2 0.7290
Carbonic anhydrase 2 P00918 CAH2_HUMAN Homo sapiens 2 0.7290
Carbonic anhydrase 2 P00918 CAH2_HUMAN Homo sapiens 2 0.7290
Pheromone-binding protein ASP1 Q9U9J6 Q9U9J6_APIME Apis mellifera 2 0.7290
Beta-secretase 1 P56817 BACE1_HUMAN Homo sapiens 2 0.7285
Beta-secretase 1 P56817 BACE1_HUMAN Homo sapiens 2 0.7285
Vitamin D-binding protein P02774 VTDB_HUMAN Homo sapiens 2 0.7284
Vitamin D-binding protein P02774 VTDB_HUMAN Homo sapiens 2 0.7284
Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase Q05603 COBT_SALTY Salmonella typhimurium 2 0.7281
ATP-dependent molecular chaperone HSP82 P02829 HSP82_YEAST Saccharomyces cerevisiae 3 0.7281
Bifunctional epoxide hydrolase 2 P34913 HYES_HUMAN Homo sapiens 2 0.7281
Bifunctional epoxide hydrolase 2 P34913 HYES_HUMAN Homo sapiens 2 0.7281
ATP-dependent molecular chaperone HSP82 P02829 HSP82_YEAST Saccharomyces cerevisiae 3 0.7281
Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase Q05603 COBT_SALTY Salmonella typhimurium 2 0.7281
2-phospho-L-lactate transferase Q8PVT6 COFD_METMA Methanosarcina mazei 2 0.7279
2-phospho-L-lactate transferase Q8PVT6 COFD_METMA Methanosarcina mazei 2 0.7279
Acyl-CoA:acyl-CoA alkyltransferase Q8PDX2 OLEA_XANCP Xanthomonas campestris pv. campestris 3 0.7278
Acyl-CoA:acyl-CoA alkyltransferase Q8PDX2 OLEA_XANCP Xanthomonas campestris pv. campestris 3 0.7278
Cyclin-dependent kinase 2 P24941 CDK2_HUMAN Homo sapiens 3 0.7274
Cyclin-dependent kinase 2 P24941 CDK2_HUMAN Homo sapiens 3 0.7274
Focal adhesion kinase 1 Q05397 FAK1_HUMAN Homo sapiens 3 0.7273
Focal adhesion kinase 1 Q05397 FAK1_HUMAN Homo sapiens 3 0.7273
Tyrosine-protein kinase JAK3 P52333 JAK3_HUMAN Homo sapiens 3 0.7266
Genome polyprotein P26663 POLG_HCVBK Hepatitis C virus genotype 1b 3 0.7266
Genome polyprotein P26663 POLG_HCVBK Hepatitis C virus genotype 1b 2 0.7266
Tyrosine-protein kinase JAK3 P52333 JAK3_HUMAN Homo sapiens 3 0.7266
Genome polyprotein P26663 POLG_HCVBK Hepatitis C virus genotype 1b 3 0.7266
HTH-type transcriptional repressor PurR P0ACP7 PURR_ECOLI Escherichia coli 2 0.7266
HTH-type transcriptional repressor PurR P0ACP7 PURR_ECOLI Escherichia coli 2 0.7266
Genome polyprotein P26663 POLG_HCVBK Hepatitis C virus genotype 1b 2 0.7266
Serine hydroxymethyltransferase Q7SIB6 Q7SIB6_GEOSE Geobacillus stearothermophilus 3 0.7264
Serine hydroxymethyltransferase Q7SIB6 Q7SIB6_GEOSE Geobacillus stearothermophilus 3 0.7264
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A Q9Y233 PDE10_HUMAN Homo sapiens 2 0.7264
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A Q9Y233 PDE10_HUMAN Homo sapiens 2 0.7264
Basic phospholipase A2 VRV-PL-VIIIa P59071 PA2B8_DABRR Daboia russelii 2 0.7263
Basic phospholipase A2 VRV-PL-VIIIa P59071 PA2B8_DABRR Daboia russelii 2 0.7263
Tyrosine-protein kinase JAK2 O60674 JAK2_HUMAN Homo sapiens 3 0.7262
Tyrosine-protein kinase JAK2 O60674 JAK2_HUMAN Homo sapiens 3 0.7262
Casein kinase I isoform gamma-3 Q9Y6M4 KC1G3_HUMAN Homo sapiens 3 0.7261
Casein kinase I isoform gamma-3 Q9Y6M4 KC1G3_HUMAN Homo sapiens 3 0.7261
Gag-Pol polyprotein P12497 POL_HV1N5 Human immunodeficiency virus type 1 group M subtype B 2 0.7260
Gag-Pol polyprotein P12497 POL_HV1N5 Human immunodeficiency virus type 1 group M subtype B 2 0.7260
Aldo-keto reductase family 1 member C3 P42330 AK1C3_HUMAN Homo sapiens 2 0.7259
Aldo-keto reductase family 1 member C3 P42330 AK1C3_HUMAN Homo sapiens 2 0.7259
cGMP-dependent protein kinase 1 Q13976 KGP1_HUMAN Homo sapiens 2 0.7259
cGMP-dependent protein kinase 1 Q13976 KGP1_HUMAN Homo sapiens 2 0.7259
Glycogen phosphorylase, muscle form P00489 PYGM_RABIT Oryctolagus cuniculus 3 0.7255
Thermolysin P00800 THER_BACTH Bacillus thermoproteolyticus 2 0.7255
Thermolysin P00800 THER_BACTH Bacillus thermoproteolyticus 2 0.7255
Glycogen phosphorylase, muscle form P00489 PYGM_RABIT Oryctolagus cuniculus 3 0.7255
Heat shock protein HSP 90-alpha P07900 HS90A_HUMAN Homo sapiens 3 0.7249
Nitric oxide synthase, inducible P29477 NOS2_MOUSE Mus musculus 3 0.7249
Heat shock protein HSP 90-alpha P07900 HS90A_HUMAN Homo sapiens 3 0.7249
Nitric oxide synthase, inducible P29477 NOS2_MOUSE Mus musculus 3 0.7249
Carbonic anhydrase 2 P00918 CAH2_HUMAN Homo sapiens 2 0.7247
Ephrin type-B receptor 2 P54763 EPHB2_MOUSE Mus musculus 2 0.7247
Carbonic anhydrase 2 P00918 CAH2_HUMAN Homo sapiens 2 0.7247
Ephrin type-B receptor 2 P54763 EPHB2_MOUSE Mus musculus 2 0.7247
Queuine tRNA-ribosyltransferase P28720 TGT_ZYMMO Zymomonas mobilis subsp. mobilis 3 0.7244
Queuine tRNA-ribosyltransferase P28720 TGT_ZYMMO Zymomonas mobilis subsp. mobilis 3 0.7244
Nitric oxide synthase, inducible P29477 NOS2_MOUSE Mus musculus 3 0.7243
Nitric oxide synthase, inducible P29477 NOS2_MOUSE Mus musculus 3 0.7243
Proto-oncogene tyrosine-protein kinase Src P12931 SRC_HUMAN Homo sapiens 3 0.7242
Proto-oncogene tyrosine-protein kinase Src P12931 SRC_HUMAN Homo sapiens 3 0.7242
Cytidine and deoxycytidylate deaminase zinc-binding region Q82Y41 Q82Y41_NITEU Nitrosomonas europaea 3 0.7241
Cytidine and deoxycytidylate deaminase zinc-binding region Q82Y41 Q82Y41_NITEU Nitrosomonas europaea 3 0.7241
Formylmethanofuran--tetrahydromethanopterin formyltransferase Q49610 FTR_METKA Methanopyrus kandleri 3 0.7240
Formylmethanofuran--tetrahydromethanopterin formyltransferase Q49610 FTR_METKA Methanopyrus kandleri 3 0.7240
Albumin P02768 ALBU_HUMAN Homo sapiens 2 0.7238
Albumin P02768 ALBU_HUMAN Homo sapiens 2 0.7238
Cytokinin dehydrogenase 1 Q9T0N8 CKX1_MAIZE Zea mays 3 0.7238
Cytokinin dehydrogenase 1 Q9T0N8 CKX1_MAIZE Zea mays 3 0.7238
ATP-dependent molecular chaperone HSP82 P02829 HSP82_YEAST Saccharomyces cerevisiae 3 0.7237
ATP-dependent molecular chaperone HSP82 P02829 HSP82_YEAST Saccharomyces cerevisiae 3 0.7237
Pteridine reductase 1 Q01782 PTR1_LEIMA Leishmania major 3 0.7232
Pteridine reductase 1 Q01782 PTR1_LEIMA Leishmania major 3 0.7232
Gag-Pol polyprotein O12158 POL_HV192 Human immunodeficiency virus type 1 group M subtype C 3 0.7230
Gag-Pol polyprotein O12158 POL_HV192 Human immunodeficiency virus type 1 group M subtype C 3 0.7230
Coagulation factor X P00742 FA10_HUMAN Homo sapiens 2 0.7230
Coagulation factor X P00742 FA10_HUMAN Homo sapiens 2 0.7230
Capsid protein Q9WBP8 Q9WBP8_9VIRU Adeno-associated virus - 1 2 0.7229
Capsid protein Q9WBP8 Q9WBP8_9VIRU Adeno-associated virus - 1 2 0.7229
Isoliquiritigenin 2'-O-methyltransferase P93324 CHOMT_MEDSA Medicago sativa 3 0.7225
cAMP-dependent protein kinase catalytic subunit alpha P00517 KAPCA_BOVIN Bos taurus 3 0.7225
cGMP-dependent protein kinase 1 P00516 KGP1_BOVIN Bos taurus 3 0.7225
Isoliquiritigenin 2'-O-methyltransferase P93324 CHOMT_MEDSA Medicago sativa 3 0.7225
cAMP-dependent protein kinase catalytic subunit alpha P00517 KAPCA_BOVIN Bos taurus 3 0.7225
cGMP-dependent protein kinase 1 P00516 KGP1_BOVIN Bos taurus 3 0.7225
Orf1a polyprotein Q692E5 Q692E5_CVHSA SARS coronavirus TJF 2 0.7223
Orf1a polyprotein Q692E5 Q692E5_CVHSA SARS coronavirus TJF 2 0.7223
Prothrombin P00734 THRB_HUMAN Homo sapiens 2 0.7222
Prothrombin P00734 THRB_HUMAN Homo sapiens 2 0.7222
Type IV / VI secretion system DotU domain-containing protein Q9KN50 Q9KN50_VIBCH Vibrio cholerae serotype O1 3 0.7219
Type IV / VI secretion system DotU domain-containing protein Q9KN50 Q9KN50_VIBCH Vibrio cholerae serotype O1 3 0.7219
Histone deacetylase 8 Q9BY41 HDAC8_HUMAN Homo sapiens 3 0.7218
Heat shock protein HSP 90-alpha P07900 HS90A_HUMAN Homo sapiens 4 0.7218
Heat shock protein HSP 90-alpha P07900 HS90A_HUMAN Homo sapiens 4 0.7218
Histone deacetylase 8 Q9BY41 HDAC8_HUMAN Homo sapiens 3 0.7218
Tyrosine-protein kinase SYK P43405 KSYK_HUMAN Homo sapiens 3 0.7217
Tyrosine-protein kinase SYK P43405 KSYK_HUMAN Homo sapiens 3 0.7217
Plasma membrane ATPase Q42932 Q42932_NICPL Nicotiana plumbaginifolia 2 0.7216
Plasma membrane ATPase Q42932 Q42932_NICPL Nicotiana plumbaginifolia 2 0.7216
Pteridine reductase, putative Q581W1 Q581W1_TRYB2 Trypanosoma brucei brucei 3 0.7215
Pteridine reductase, putative Q581W1 Q581W1_TRYB2 Trypanosoma brucei brucei 3 0.7215
Nitric oxide synthase, inducible P29477 NOS2_MOUSE Mus musculus 3 0.7214
Nitric oxide synthase, inducible P29477 NOS2_MOUSE Mus musculus 3 0.7214
Cyclic GMP-AMP phosphodiesterase SMPDL3A Q92484 ASM3A_HUMAN Homo sapiens 2 0.7213
Cyclic GMP-AMP phosphodiesterase SMPDL3A Q92484 ASM3A_HUMAN Homo sapiens 2 0.7213
Adenylate cyclase type 5 P30803 ADCY5_CANLF Canis lupus familiaris 3 0.7208
Adenylate cyclase type 5 P30803 ADCY5_CANLF Canis lupus familiaris 3 0.7208
Serine/threonine-protein kinase PLK1 P53350 PLK1_HUMAN Homo sapiens 3 0.7207
Serine/threonine-protein kinase PLK1 P53350 PLK1_HUMAN Homo sapiens 3 0.7207
5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase Q81LL4 MTNN_BACAN Bacillus anthracis 2 0.7206
5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase Q81LL4 MTNN_BACAN Bacillus anthracis 2 0.7206
Pantothenate synthetase P9WIL5 PANC_MYCTU Mycobacterium tuberculosis 3 0.7202
MAP kinase-activated protein kinase 2 P49137 MAPK2_HUMAN Homo sapiens 3 0.7202
Prothrombin P00734 THRB_HUMAN Homo sapiens 2 0.7202
MAP kinase-activated protein kinase 2 P49137 MAPK2_HUMAN Homo sapiens 3 0.7202
Prothrombin P00734 THRB_HUMAN Homo sapiens 2 0.7202
Pantothenate synthetase P9WIL5 PANC_MYCTU Mycobacterium tuberculosis 3 0.7202
Steroid Delta-isomerase P00947 SDIS_COMTE Comamonas testosteroni 2 0.7200
Steroid Delta-isomerase P00947 SDIS_COMTE Comamonas testosteroni 2 0.7200
Genome polyprotein Q6YMS4 POLG_DEN3S Dengue virus type 3 3 0.7198
Genome polyprotein Q6YMS4 POLG_DEN3S Dengue virus type 3 3 0.7198
Tyrosine-protein kinase Lck P06239 LCK_HUMAN Homo sapiens 3 0.7197
Tyrosine-protein kinase Lck P06239 LCK_HUMAN Homo sapiens 3 0.7197
MAP kinase-activated protein kinase 2 P49137 MAPK2_HUMAN Homo sapiens 3 0.7195
UTP-monosaccharide-1-phosphate uridylyltransferase D3G6S4 D3G6S4_LEIMA Leishmania major 3 0.7195
MAP kinase-activated protein kinase 2 P49137 MAPK2_HUMAN Homo sapiens 3 0.7195
UTP-monosaccharide-1-phosphate uridylyltransferase D3G6S4 D3G6S4_LEIMA Leishmania major 3 0.7195
Ferric enterobactin-binding periplasmic protein FepB P0AEL6 FEPB_ECOLI Escherichia coli 4 0.7194
Ferric enterobactin-binding periplasmic protein FepB P0AEL6 FEPB_ECOLI Escherichia coli 4 0.7194
L-lactate dehydrogenase A chain P13491 LDHA_RABIT Oryctolagus cuniculus 2 0.7193
L-lactate dehydrogenase A chain P13491 LDHA_RABIT Oryctolagus cuniculus 2 0.7193
Glutamate receptor 2 P19491 GRIA2_RAT Rattus norvegicus 2 0.7191
Glutamate receptor 2 P19491 GRIA2_RAT Rattus norvegicus 2 0.7191
Gag-Pol polyprotein P03367 POL_HV1BR Human immunodeficiency virus type 1 group M subtype B 2 0.7190
Inorganic pyrophosphatase Q3JUV5 Q3JUV5_BURP1 Burkholderia pseudomallei 2 0.7190
Gag-Pol polyprotein P03367 POL_HV1BR Human immunodeficiency virus type 1 group M subtype B 2 0.7190
Inorganic pyrophosphatase Q3JUV5 Q3JUV5_BURP1 Burkholderia pseudomallei 2 0.7190
[LysW]-aminoadipate kinase O50147 LYSZ_THET2 Thermus thermophilus 3 0.7184
[LysW]-aminoadipate kinase O50147 LYSZ_THET2 Thermus thermophilus 3 0.7184
Dipeptidyl peptidase 4 P27487 DPP4_HUMAN Homo sapiens 3 0.7182
Dipeptidyl peptidase 4 P27487 DPP4_HUMAN Homo sapiens 3 0.7182
HTH-type transcriptional repressor PurR P0ACP7 PURR_ECOLI Escherichia coli 2 0.7181
HTH-type transcriptional repressor PurR P0ACP7 PURR_ECOLI Escherichia coli 2 0.7181
Non-receptor tyrosine-protein kinase TYK2 P29597 TYK2_HUMAN Homo sapiens 3 0.7180
Non-receptor tyrosine-protein kinase TYK2 P29597 TYK2_HUMAN Homo sapiens 3 0.7180
Mitogen-activated protein kinase 14 Q16539 MK14_HUMAN Homo sapiens 3 0.7179
Mitogen-activated protein kinase 14 Q16539 MK14_HUMAN Homo sapiens 3 0.7179
AcsD Q93AT8 Q93AT8_DICCH Dickeya chrysanthemi 3 0.7177
AcsD Q93AT8 Q93AT8_DICCH Dickeya chrysanthemi 3 0.7177
Ephrin type-B receptor 4 P54760 EPHB4_HUMAN Homo sapiens 3 0.7175
Ephrin type-B receptor 4 P54760 EPHB4_HUMAN Homo sapiens 3 0.7175
Mitogen-activated protein kinase 14 Q16539 MK14_HUMAN Homo sapiens 3 0.7173
Mitogen-activated protein kinase 14 Q16539 MK14_HUMAN Homo sapiens 3 0.7173
Nitric oxide synthase, inducible P29477 NOS2_MOUSE Mus musculus 3 0.7173
Nitric oxide synthase, inducible P29477 NOS2_MOUSE Mus musculus 3 0.7173
Neutrophil gelatinase-associated lipocalin P80188 NGAL_HUMAN Homo sapiens 2 0.7170
Neutrophil gelatinase-associated lipocalin P80188 NGAL_HUMAN Homo sapiens 2 0.7170
1-deoxy-D-xylulose 5-phosphate reductoisomerase P45568 DXR_ECOLI Escherichia coli 2 0.7168
1-deoxy-D-xylulose 5-phosphate reductoisomerase P45568 DXR_ECOLI Escherichia coli 2 0.7168
Poly [ADP-ribose] polymerase tankyrase-2 Q9H2K2 TNKS2_HUMAN Homo sapiens 4 0.7167
Poly [ADP-ribose] polymerase tankyrase-2 Q9H2K2 TNKS2_HUMAN Homo sapiens 4 0.7167
F420-dependent methylenetetrahydromethanopterin dehydrogenase P94951 MTD_METKA Methanopyrus kandleri 2 0.7166
F420-dependent methylenetetrahydromethanopterin dehydrogenase P94951 MTD_METKA Methanopyrus kandleri 2 0.7166
Polymerase acidic protein P03433 PA_I34A1 Influenza A virus 2 0.7164
Polymerase acidic protein P03433 PA_I34A1 Influenza A virus 2 0.7164
Precorrin-3 methylase O68097 O68097_RHOCA Rhodobacter capsulatus 3 0.7162
Precorrin-3 methylase O68097 O68097_RHOCA Rhodobacter capsulatus 3 0.7162
Serine/threonine-protein kinase pim-1 P11309 PIM1_HUMAN Homo sapiens 3 0.7160
Serine/threonine-protein kinase pim-1 P11309 PIM1_HUMAN Homo sapiens 3 0.7160
Mycocyclosin synthase P9WPP7 CP121_MYCTU Mycobacterium tuberculosis 3 0.7159
Mycocyclosin synthase P9WPP7 CP121_MYCTU Mycobacterium tuberculosis 3 0.7159
Purine nucleoside phosphorylase DeoD-type B1JL34 DEOD_YERPY Yersinia pseudotuberculosis serotype O:3 2 0.7158
Purine nucleoside phosphorylase DeoD-type B1JL34 DEOD_YERPY Yersinia pseudotuberculosis serotype O:3 2 0.7158
Mitogen-activated protein kinase 14 Q16539 MK14_HUMAN Homo sapiens 3 0.7155
Mitogen-activated protein kinase 14 Q16539 MK14_HUMAN Homo sapiens 3 0.7155
Gentisate 1,2-dioxygenase Q67FT0 Q67FT0_PSESE Pseudaminobacter salicylatoxidans 2 0.7154
Gentisate 1,2-dioxygenase Q67FT0 Q67FT0_PSESE Pseudaminobacter salicylatoxidans 2 0.7154
Carbonic anhydrase 2 P00918 CAH2_HUMAN Homo sapiens 2 0.7153
Serine/threonine-protein kinase pim-1 P11309 PIM1_HUMAN Homo sapiens 3 0.7153
Serine/threonine-protein kinase pim-1 P11309 PIM1_HUMAN Homo sapiens 3 0.7153
Carbonic anhydrase 2 P00918 CAH2_HUMAN Homo sapiens 2 0.7153
N-acetyltransferase domain-containing protein Q9HV14 Q9HV14_PSEAE Pseudomonas aeruginosa 2 0.7152
UDP-N-acetylglucosamine 1-carboxyvinyltransferase P33038 MURA_ENTCC Enterobacter cloacae subsp. cloacae 2 0.7152
UDP-N-acetylglucosamine 1-carboxyvinyltransferase P33038 MURA_ENTCC Enterobacter cloacae subsp. cloacae 2 0.7152
N-acetyltransferase domain-containing protein Q9HV14 Q9HV14_PSEAE Pseudomonas aeruginosa 2 0.7152
ATP-dependent molecular chaperone HSP82 P02829 HSP82_YEAST Saccharomyces cerevisiae 2 0.7151
ATP-dependent molecular chaperone HSP82 P02829 HSP82_YEAST Saccharomyces cerevisiae 2 0.7151
Botulinum neurotoxin type A P0DPI0 BXA1_CLOBO Clostridium botulinum 2 0.7146
Botulinum neurotoxin type A P0DPI0 BXA1_CLOBO Clostridium botulinum 2 0.7146
Putative ketoacyl reductase P16544 ACT3_STRCO Streptomyces coelicolor / M145) 3 0.7141
Putative ketoacyl reductase P16544 ACT3_STRCO Streptomyces coelicolor / M145) 3 0.7141
Carbonyl reductase [NADPH] 1 P16152 CBR1_HUMAN Homo sapiens 3 0.7140
Carbonyl reductase [NADPH] 1 P16152 CBR1_HUMAN Homo sapiens 3 0.7140
Beta-secretase 2 Q9Y5Z0 BACE2_HUMAN Homo sapiens 2 0.7131
Nitric oxide synthase 1 P29476 NOS1_RAT Rattus norvegicus 3 0.7131
Beta-secretase 2 Q9Y5Z0 BACE2_HUMAN Homo sapiens 2 0.7131
Nitric oxide synthase 1 P29476 NOS1_RAT Rattus norvegicus 3 0.7131
Trichothecene 15-O-acetyltransferase TRI3 Q9C1B7 TRI3_FUSSP Fusarium sporotrichioides 3 0.7129
Trichothecene 15-O-acetyltransferase TRI3 Q9C1B7 TRI3_FUSSP Fusarium sporotrichioides 3 0.7129
Nitric oxide synthase, inducible P29477 NOS2_MOUSE Mus musculus 3 0.7129
Nitric oxide synthase, inducible P29477 NOS2_MOUSE Mus musculus 3 0.7129
Proto-oncogene tyrosine-protein kinase Src P00523 SRC_CHICK Gallus gallus 3 0.7128
Proto-oncogene tyrosine-protein kinase Src P00523 SRC_CHICK Gallus gallus 3 0.7128
Orotidine 5'-phosphate decarboxylase O26232 PYRF_METTH Methanothermobacter thermautotrophicus 3 0.7126
Orotidine 5'-phosphate decarboxylase O26232 PYRF_METTH Methanothermobacter thermautotrophicus 3 0.7126
Hepatocyte growth factor receptor P08581 MET_HUMAN Homo sapiens 2 0.7125
Hepatocyte growth factor receptor P08581 MET_HUMAN Homo sapiens 2 0.7125
Tannase B3Y018 B3Y018_LACPN Lactiplantibacillus plantarum 3 0.7125
Tannase B3Y018 B3Y018_LACPN Lactiplantibacillus plantarum 3 0.7125
Mitogen-activated protein kinase 8 P45983 MK08_HUMAN Homo sapiens 2 0.7123
Mitogen-activated protein kinase 8 P45983 MK08_HUMAN Homo sapiens 2 0.7123
Tannase B3Y018 B3Y018_LACPN Lactiplantibacillus plantarum 3 0.7122
Tannase B3Y018 B3Y018_LACPN Lactiplantibacillus plantarum 3 0.7122
Tetracycline repressor protein class B from transposon Tn10 P04483 TETR2_ECOLX Escherichia coli 2 0.7120
Tetracycline repressor protein class B from transposon Tn10 P04483 TETR2_ECOLX Escherichia coli 2 0.7120
Heat shock protein 75 kDa, mitochondrial Q12931 TRAP1_HUMAN Homo sapiens 4 0.7119
HD domain protein Q836G9 Q836G9_ENTFA Enterococcus faecalis 3 0.7119
Heat shock protein 75 kDa, mitochondrial Q12931 TRAP1_HUMAN Homo sapiens 4 0.7119
HD domain protein Q836G9 Q836G9_ENTFA Enterococcus faecalis 3 0.7119
Coagulation factor X P00742 FA10_HUMAN Homo sapiens 3 0.7117
Coagulation factor X P00742 FA10_HUMAN Homo sapiens 3 0.7117
Phospholipase A2, major isoenzyme P00592 PA21B_PIG Sus scrofa 2 0.7117
Phospholipase A2, major isoenzyme P00592 PA21B_PIG Sus scrofa 2 0.7117
Aldo-keto reductase family 1 member C3 P42330 AK1C3_HUMAN Homo sapiens 3 0.7114
Malate dehydrogenase P10584 MDH_THETH Thermus thermophilus 3 0.7114
Malate dehydrogenase P10584 MDH_THETH Thermus thermophilus 3 0.7114
Aldo-keto reductase family 1 member C3 P42330 AK1C3_HUMAN Homo sapiens 3 0.7114
Cellular tumor antigen p53 P04637 P53_HUMAN Homo sapiens 3 0.7112
Cellular tumor antigen p53 P04637 P53_HUMAN Homo sapiens 3 0.7112
Prothrombin P00734 THRB_HUMAN Homo sapiens 3 0.7111
Prothrombin P00734 THRB_HUMAN Homo sapiens 3 0.7111
Thymidylate synthase P00469 TYSY_LACCA Lacticaseibacillus casei 2 0.7110
Thymidylate synthase P00469 TYSY_LACCA Lacticaseibacillus casei 2 0.7110
Insulin-degrading enzyme P14735 IDE_HUMAN Homo sapiens 2 0.7109
Holliday junction branch migration complex subunit RuvB Q9PMT7 RUVB_CAMJE Campylobacter jejuni subsp. jejuni serotype O:2 2 0.7109
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform P48736 PK3CG_HUMAN Homo sapiens 3 0.7109
Holliday junction branch migration complex subunit RuvB Q9PMT7 RUVB_CAMJE Campylobacter jejuni subsp. jejuni serotype O:2 2 0.7109
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform P48736 PK3CG_HUMAN Homo sapiens 3 0.7109
Insulin-degrading enzyme P14735 IDE_HUMAN Homo sapiens 2 0.7109
Serine/threonine-protein kinase Chk2 O96017 CHK2_HUMAN Homo sapiens 2 0.7108
Serine/threonine-protein kinase Chk2 O96017 CHK2_HUMAN Homo sapiens 2 0.7108
Casein kinase II subunit alpha P68400 CSK21_HUMAN Homo sapiens 3 0.7107
Casein kinase II subunit alpha P68400 CSK21_HUMAN Homo sapiens 3 0.7107
CREB-binding protein Q92793 CBP_HUMAN Homo sapiens 2 0.7106
YbaK/aminoacyl-tRNA synthetase-associated domain-containing protein Q5SHN1 Q5SHN1_THET8 Thermus thermophilus 3 0.7106
CREB-binding protein Q92793 CBP_HUMAN Homo sapiens 2 0.7106
YbaK/aminoacyl-tRNA synthetase-associated domain-containing protein Q5SHN1 Q5SHN1_THET8 Thermus thermophilus 3 0.7106
Catechol O-methyltransferase P22734 COMT_RAT Rattus norvegicus 3 0.7105
Catechol O-methyltransferase P22734 COMT_RAT Rattus norvegicus 3 0.7105
HTH-type transcriptional repressor PurR P0ACP7 PURR_ECOLI Escherichia coli 3 0.7102
HTH-type transcriptional repressor PurR P0ACP7 PURR_ECOLI Escherichia coli 3 0.7102
CCA-adding enzyme O28126 CCA_ARCFU Archaeoglobus fulgidus 2 0.7102
CCA-adding enzyme O28126 CCA_ARCFU Archaeoglobus fulgidus 2 0.7102
Tryptase alpha/beta-1 Q15661 TRYB1_HUMAN Homo sapiens 3 0.7101
Seed lectin subunit I P05045 LEC1_VIGUC Vigna unguiculata subsp. cylindrica 2 0.7101
Seed lectin subunit I P05045 LEC1_VIGUC Vigna unguiculata subsp. cylindrica 2 0.7101
Tryptase alpha/beta-1 Q15661 TRYB1_HUMAN Homo sapiens 3 0.7101
Subunit alpha of sarocosine oxidase Q50LF0 Q50LF0_9CORY Corynebacterium sp. U-96 3 0.7100
Subunit alpha of sarocosine oxidase Q50LF0 Q50LF0_9CORY Corynebacterium sp. U-96 3 0.7100
Bis(5'-adenosyl)-triphosphatase P49789 FHIT_HUMAN Homo sapiens 2 0.7099
Bis(5'-adenosyl)-triphosphatase P49789 FHIT_HUMAN Homo sapiens 2 0.7099
Gag-Pol polyprotein P04585 POL_HV1H2 Human immunodeficiency virus type 1 group M subtype B 3 0.7098
Amino-acid acetyltransferase Q5FAK7 Q5FAK7_NEIG1 Neisseria gonorrhoeae 2 0.7098
Amino-acid acetyltransferase Q5FAK7 Q5FAK7_NEIG1 Neisseria gonorrhoeae 2 0.7098
Gag-Pol polyprotein P04585 POL_HV1H2 Human immunodeficiency virus type 1 group M subtype B 3 0.7098
Deacetoxycephalosporin C synthase P18548 CEFE_STRCL Streptomyces clavuligerus 2 0.7097
Aldo-keto reductase family 1 member B1 P15121 ALDR_HUMAN Homo sapiens 2 0.7097
Deacetoxycephalosporin C synthase P18548 CEFE_STRCL Streptomyces clavuligerus 2 0.7097
Aldo-keto reductase family 1 member B1 P15121 ALDR_HUMAN Homo sapiens 2 0.7097
Tetracycline repressor protein class D P0ACT4 TETR4_ECOLX Escherichia coli 3 0.7096
Tetracycline repressor protein class D P0ACT4 TETR4_ECOLX Escherichia coli 3 0.7096
Nitric oxide synthase, inducible P29477 NOS2_MOUSE Mus musculus 3 0.7095
Nitric oxide synthase, inducible P29477 NOS2_MOUSE Mus musculus 3 0.7095
CCA-adding enzyme O28126 CCA_ARCFU Archaeoglobus fulgidus 2 0.7093
CCA-adding enzyme O28126 CCA_ARCFU Archaeoglobus fulgidus 2 0.7093
Single-stranded-DNA-specific exonuclease RecJ D0EM60 D0EM60_DEIRD Deinococcus radiodurans 2 0.7093
Single-stranded-DNA-specific exonuclease RecJ D0EM60 D0EM60_DEIRD Deinococcus radiodurans 2 0.7093
Uncharacterized protein YML079W Q03629 YMH9_YEAST Saccharomyces cerevisiae 2 0.7092
Uncharacterized protein YML079W Q03629 YMH9_YEAST Saccharomyces cerevisiae 2 0.7092
Peptidyl-prolyl cis-trans isomerase FKBP5 Q13451 FKBP5_HUMAN Homo sapiens 3 0.7092
Peptidyl-prolyl cis-trans isomerase FKBP5 Q13451 FKBP5_HUMAN Homo sapiens 3 0.7092
Tetracycline repressor protein class D P0ACT4 TETR4_ECOLX Escherichia coli 3 0.7089
Tetracycline repressor protein class D P0ACT4 TETR4_ECOLX Escherichia coli 3 0.7089
Dihydropteroate synthase Q81VW8 Q81VW8_BACAN Bacillus anthracis 2 0.7089
Dihydropteroate synthase Q81VW8 Q81VW8_BACAN Bacillus anthracis 2 0.7089
Thymidine kinase P0DTH5 KITH_HHV11 Human herpesvirus 1 2 0.7088
Thymidine kinase P0DTH5 KITH_HHV11 Human herpesvirus 1 2 0.7088
Tyrosine-protein kinase JAK2 O60674 JAK2_HUMAN Homo sapiens 2 0.7087
Tyrosine-protein kinase JAK2 O60674 JAK2_HUMAN Homo sapiens 2 0.7087
3-phosphoinositide-dependent protein kinase 1 O15530 PDPK1_HUMAN Homo sapiens 4 0.7086
3-phosphoinositide-dependent protein kinase 1 O15530 PDPK1_HUMAN Homo sapiens 4 0.7086
Proliferating cell nuclear antigen P12004 PCNA_HUMAN Homo sapiens 3 0.7084
Proliferating cell nuclear antigen P12004 PCNA_HUMAN Homo sapiens 3 0.7084
Metallophosphoesterase MPPED2 B1WBP0 MPPD2_RAT Rattus norvegicus 3 0.7083
Norsolorinic acid synthase Q12053 AFLC_ASPPU Aspergillus parasiticus 2 0.7083
Norsolorinic acid synthase Q12053 AFLC_ASPPU Aspergillus parasiticus 2 0.7083
Metallophosphoesterase MPPED2 B1WBP0 MPPD2_RAT Rattus norvegicus 3 0.7083
Carbonic anhydrase 4 Q64444 CAH4_MOUSE Mus musculus 2 0.7079
Carbonic anhydrase 4 Q64444 CAH4_MOUSE Mus musculus 2 0.7079
Beta-2 adrenergic receptor P07550 ADRB2_HUMAN Homo sapiens 2 0.7076
Aurora kinase A O14965 AURKA_HUMAN Homo sapiens 4 0.7076
Beta-2 adrenergic receptor P07550 ADRB2_HUMAN Homo sapiens 2 0.7076
Aurora kinase A O14965 AURKA_HUMAN Homo sapiens 4 0.7076
Photosynthetic reaction center cytochrome c subunit P07173 CYCR_BLAVI Blastochloris viridis 2 0.7074
Photosynthetic reaction center cytochrome c subunit P07173 CYCR_BLAVI Blastochloris viridis 2 0.7074
LIM domain kinase 1 P53667 LIMK1_HUMAN Homo sapiens 2 0.7072
LIM domain kinase 1 P53667 LIMK1_HUMAN Homo sapiens 2 0.7072
Secoisolariciresinol dehydrogenase Q94KL8 SILD_PODPE Podophyllum peltatum 3 0.7072
Secoisolariciresinol dehydrogenase Q94KL8 SILD_PODPE Podophyllum peltatum 3 0.7072
Ephrin type-B receptor 4 P54760 EPHB4_HUMAN Homo sapiens 3 0.7069
Ephrin type-B receptor 4 P54760 EPHB4_HUMAN Homo sapiens 3 0.7069
Heat shock protein HSP 90-alpha P07900 HS90A_HUMAN Homo sapiens 3 0.7068
Heat shock protein HSP 90-alpha P07900 HS90A_HUMAN Homo sapiens 3 0.7068
5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase P0AF12 MTNN_ECOLI Escherichia coli 2 0.7068
5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase P0AF12 MTNN_ECOLI Escherichia coli 2 0.7068
Pyridoxal kinase O00764 PDXK_HUMAN Homo sapiens 2 0.7068
Pyridoxal kinase O00764 PDXK_HUMAN Homo sapiens 2 0.7068
Adenylate cyclase type 5 P30803 ADCY5_CANLF Canis lupus familiaris 4 0.7066
Adenylate cyclase type 5 P30803 ADCY5_CANLF Canis lupus familiaris 4 0.7066
Urokinase-type plasminogen activator P00749 UROK_HUMAN Homo sapiens 2 0.7065
Poly [ADP-ribose] polymerase 1 P09874 PARP1_HUMAN Homo sapiens 3 0.7065
Poly [ADP-ribose] polymerase 1 P09874 PARP1_HUMAN Homo sapiens 3 0.7065
ABC-type polar amino acid transport system, ATPase component Q8RCC2 Q8RCC2_CALS4 Caldanaerobacter subterraneus subsp. tengcongensis 2 0.7065
Urokinase-type plasminogen activator P00749 UROK_HUMAN Homo sapiens 2 0.7065
ABC-type polar amino acid transport system, ATPase component Q8RCC2 Q8RCC2_CALS4 Caldanaerobacter subterraneus subsp. tengcongensis 2 0.7065
Purine nucleoside phosphorylase DeoD-type P0ABP9 DEOD_ECO57 Escherichia coli O157:H7 2 0.7063
Purine nucleoside phosphorylase DeoD-type P0ABP9 DEOD_ECO57 Escherichia coli O157:H7 2 0.7063
Queuine tRNA-ribosyltransferase P28720 TGT_ZYMMO Zymomonas mobilis subsp. mobilis 3 0.7062
Queuine tRNA-ribosyltransferase P28720 TGT_ZYMMO Zymomonas mobilis subsp. mobilis 3 0.7062
S-methyl-5'-thioadenosine phosphorylase Q13126 MTAP_HUMAN Homo sapiens 2 0.7061
S-methyl-5'-thioadenosine phosphorylase Q13126 MTAP_HUMAN Homo sapiens 2 0.7061
UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--LD-lysine ligase Q9WY79 MURE_THEMA Thermotoga maritima 3 0.7061
UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--LD-lysine ligase Q9WY79 MURE_THEMA Thermotoga maritima 3 0.7061
Cyclin-dependent kinase 2 P24941 CDK2_HUMAN Homo sapiens 2 0.7060
Ribosyldihydronicotinamide dehydrogenase [quinone] P16083 NQO2_HUMAN Homo sapiens 3 0.7060
Nitric oxide synthase 3 P29474 NOS3_HUMAN Homo sapiens 2 0.7060
Uracil phosphoribosyltransferase Q26998 UPP_TOXGO Toxoplasma gondii 3 0.7060
Cyclin-dependent kinase 2 P24941 CDK2_HUMAN Homo sapiens 2 0.7060
Ribosyldihydronicotinamide dehydrogenase [quinone] P16083 NQO2_HUMAN Homo sapiens 3 0.7060
Nitric oxide synthase 3 P29474 NOS3_HUMAN Homo sapiens 2 0.7060
Uracil phosphoribosyltransferase Q26998 UPP_TOXGO Toxoplasma gondii 3 0.7060
Tetracycline repressor protein class D P0ACT4 TETR4_ECOLX Escherichia coli 3 0.7058
Tetracycline repressor protein class D P0ACT4 TETR4_ECOLX Escherichia coli 3 0.7058
Tetracycline repressor protein class D P0ACT4 TETR4_ECOLX Escherichia coli 3 0.7057
Tetracycline repressor protein class D P0ACT4 TETR4_ECOLX Escherichia coli 3 0.7057
Endoplasmin P41148 ENPL_CANLF Canis lupus familiaris 3 0.7057
Endoplasmin P41148 ENPL_CANLF Canis lupus familiaris 3 0.7057
Purine nucleoside phosphorylase DeoD-type Q5EEL8 DEOD_BACCE Bacillus cereus 2 0.7057
Purine nucleoside phosphorylase DeoD-type Q5EEL8 DEOD_BACCE Bacillus cereus 2 0.7057
Thymidylate synthase Q9Y052 Q9Y052_CAEEL Caenorhabditis elegans 3 0.7056
Thymidylate synthase Q9Y052 Q9Y052_CAEEL Caenorhabditis elegans 3 0.7056
Cyclic AMP receptor protein Q5SID7 CRP_THET8 Thermus thermophilus 3 0.7055
Cyclic AMP receptor protein Q5SID7 CRP_THET8 Thermus thermophilus 3 0.7055
Serine/threonine-protein kinase pim-1 P11309 PIM1_HUMAN Homo sapiens 3 0.7053
3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase O33877 FABA_PSEAE Pseudomonas aeruginosa 3 0.7053
cAMP-dependent protein kinase type I-alpha regulatory subunit P00514 KAP0_BOVIN Bos taurus 3 0.7053
cAMP-dependent protein kinase type I-alpha regulatory subunit P00514 KAP0_BOVIN Bos taurus 3 0.7053
3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase O33877 FABA_PSEAE Pseudomonas aeruginosa 3 0.7053
Serine/threonine-protein kinase pim-1 P11309 PIM1_HUMAN Homo sapiens 3 0.7053
Streptavidin P22629 SAV_STRAV Streptomyces avidinii 3 0.7051
Carbonic anhydrase 1 P00915 CAH1_HUMAN Homo sapiens 2 0.7051
Streptavidin P22629 SAV_STRAV Streptomyces avidinii 3 0.7051
Carbonic anhydrase 1 P00915 CAH1_HUMAN Homo sapiens 2 0.7051
Protocatechuate 3,4-dioxygenase beta chain P00437 PCXB_PSEPU Pseudomonas putida 2 0.7048
Protocatechuate 3,4-dioxygenase beta chain P00437 PCXB_PSEPU Pseudomonas putida 2 0.7048
Mitogen-activated protein kinase 14 Q16539 MK14_HUMAN Homo sapiens 3 0.7047
Mitogen-activated protein kinase 14 Q16539 MK14_HUMAN Homo sapiens 3 0.7047
Serine/threonine-protein kinase toxin HipA P23874 HIPA_ECOLI Escherichia coli 2 0.7045
Serine/threonine-protein kinase toxin HipA P23874 HIPA_ECOLI Escherichia coli 2 0.7045
Acetolactate synthase, chloroplastic P17597 ILVB_ARATH Arabidopsis thaliana 2 0.7042
Acetolactate synthase, chloroplastic P17597 ILVB_ARATH Arabidopsis thaliana 2 0.7042
Bromodomain-containing protein 2 P25440 BRD2_HUMAN Homo sapiens 3 0.7041
Protein RecA Q59560 RECA_MYCS2 Mycolicibacterium smegmatis155) 3 0.7041
Bromodomain-containing protein 2 P25440 BRD2_HUMAN Homo sapiens 3 0.7041
Protein RecA Q59560 RECA_MYCS2 Mycolicibacterium smegmatis155) 3 0.7041
Metallophosphoesterase A3DJ38 A3DJ38_HUNT2 Clostridium thermocellum 2 0.7039
Metallophosphoesterase A3DJ38 A3DJ38_HUNT2 Clostridium thermocellum 2 0.7039
Polymerase acidic protein C3W5S0 C3W5S0_I09A0 Influenza A virus 2 0.7037
Polymerase acidic protein C3W5S0 C3W5S0_I09A0 Influenza A virus 2 0.7037
Endoplasmin P41148 ENPL_CANLF Canis lupus familiaris 3 0.7036
Endoplasmin P41148 ENPL_CANLF Canis lupus familiaris 3 0.7036
Aspartate carbamoyltransferase catalytic subunit P0A786 PYRB_ECOLI Escherichia coli 2 0.7034
Aspartate carbamoyltransferase catalytic subunit P0A786 PYRB_ECOLI Escherichia coli 2 0.7034
Fibroblast growth factor receptor 2 P21802 FGFR2_HUMAN Homo sapiens 2 0.7033
Fibroblast growth factor receptor 2 P21802 FGFR2_HUMAN Homo sapiens 2 0.7033
Oxygenase Q194P4 Q194P4_STRAA Streptomyces argillaceus 3 0.7031
Oxygenase Q194P4 Q194P4_STRAA Streptomyces argillaceus 3 0.7031
RIO-type serine/threonine-protein kinase Rio1 O28471 RIO1_ARCFU Archaeoglobus fulgidus 2 0.7028
RIO-type serine/threonine-protein kinase Rio1 O28471 RIO1_ARCFU Archaeoglobus fulgidus 2 0.7028
Protease O38896 O38896_9HIV1 Human immunodeficiency virus 1 2 0.7024
Protease O38896 O38896_9HIV1 Human immunodeficiency virus 1 2 0.7024
Ephrin type-A receptor 3 P29320 EPHA3_HUMAN Homo sapiens 3 0.7023
Ephrin type-A receptor 3 P29320 EPHA3_HUMAN Homo sapiens 3 0.7023
Phosphodiesterase Q8WQX9 Q8WQX9_9TRYP Trypanosoma brucei 3 0.7022
Phosphodiesterase Q8WQX9 Q8WQX9_9TRYP Trypanosoma brucei 3 0.7022
Carbonic anhydrase 2 P00918 CAH2_HUMAN Homo sapiens 2 0.7020
Carbonic anhydrase 2 P00918 CAH2_HUMAN Homo sapiens 2 0.7020
Purine nucleoside phosphorylase DeoD-type O34925 DEOD_BACSU Bacillus subtilis 2 0.7019
Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 Q9Y3Z3 SAMH1_HUMAN Homo sapiens 3 0.7019
Purine nucleoside phosphorylase DeoD-type O34925 DEOD_BACSU Bacillus subtilis 2 0.7019
Succinyl-CoA:acetate CoA-transferase B3EY95 SCACT_ACEAC Acetobacter aceti 2 0.7019
Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 Q9Y3Z3 SAMH1_HUMAN Homo sapiens 3 0.7019
Succinyl-CoA:acetate CoA-transferase B3EY95 SCACT_ACEAC Acetobacter aceti 2 0.7019
Beta-1 adrenergic receptor P07700 ADRB1_MELGA Meleagris gallopavo 2 0.7018
Beta-1 adrenergic receptor P07700 ADRB1_MELGA Meleagris gallopavo 2 0.7018
Beta-secretase 1 P56817 BACE1_HUMAN Homo sapiens 2 0.7017
Beta-secretase 1 P56817 BACE1_HUMAN Homo sapiens 2 0.7017
Glucosidase II subunit alpha Q9STC1 Q9STC1_GRALE Gracilariopsis lemaneiformis 3 0.7015
Glucosidase II subunit alpha Q9STC1 Q9STC1_GRALE Gracilariopsis lemaneiformis 3 0.7015
Thymidylate synthase P00469 TYSY_LACCA Lacticaseibacillus casei 3 0.7014
Thymidylate synthase P00469 TYSY_LACCA Lacticaseibacillus casei 3 0.7014
Pteridine reductase 1 Q01782 PTR1_LEIMA Leishmania major 2 0.7014
Pteridine reductase 1 Q01782 PTR1_LEIMA Leishmania major 2 0.7014
Prothrombin P00734 THRB_HUMAN Homo sapiens 2 0.7009
Prothrombin P00734 THRB_HUMAN Homo sapiens 2 0.7009
ADP compounds hydrolase NudE P45799 NUDE_ECOLI Escherichia coli 2 0.7009
ADP compounds hydrolase NudE P45799 NUDE_ECOLI Escherichia coli 2 0.7009
Glucan 1,3-beta-glucosidase P29717 EXG1_CANAL Candida albicans 2 0.7008
Glucan 1,3-beta-glucosidase P29717 EXG1_CANAL Candida albicans 2 0.7008
clade A/E 93TH057 HIV-1 gp120 core A0A0M3KKW9 A0A0M3KKW9_9HIV1 Human immunodeficiency virus 1 2 0.7008
clade A/E 93TH057 HIV-1 gp120 core A0A0M3KKW9 A0A0M3KKW9_9HIV1 Human immunodeficiency virus 1 2 0.7008
N-terminal acetyltransferase A complex subunit NAT1 P12945 NAT1_YEAST Saccharomyces cerevisiae 2 0.7006
N-terminal acetyltransferase A complex subunit NAT1 P12945 NAT1_YEAST Saccharomyces cerevisiae 2 0.7006
NAD(P)H-hydrate epimerase Q8K4Z3 NNRE_MOUSE Mus musculus 3 0.7006
NAD(P)H-hydrate epimerase Q8K4Z3 NNRE_MOUSE Mus musculus 3 0.7006
Fibroblast growth factor receptor 2 P21802 FGFR2_HUMAN Homo sapiens 2 0.7005
Fibroblast growth factor receptor 2 P21802 FGFR2_HUMAN Homo sapiens 2 0.7005
Heat shock protein HSP 90-alpha P07900 HS90A_HUMAN Homo sapiens 3 0.7005
Heat shock protein HSP 90-alpha P07900 HS90A_HUMAN Homo sapiens 3 0.7005
LD-carboxypeptidase A0A6L8PVW7 A0A1Q4LWC0_BACAN Bacillus anthracis 3 0.7003
LD-carboxypeptidase A0A6L8PVW7 A0A1Q4LWC0_BACAN Bacillus anthracis 3 0.7003
Serine/threonine-protein kinase 24 Q9Y6E0 STK24_HUMAN Homo sapiens 2 0.7001
Serine/threonine-protein kinase 24 Q9Y6E0 STK24_HUMAN Homo sapiens 2 0.7001

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