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Heptadecanoic acid
- Family: Plantae - Sterculiaceae
- Kingdom: Plantae
-
Class: Lipid
- Subclass: Fatty Acid
Canonical Smiles | CCCCCCCCCCCCCCCCC(=O)O |
---|---|
InChI | InChI=1S/C17H34O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17(18)19/h2-16H2,1H3,(H,18,19) |
InChIKey | KEMQGTRYUADPNZ-UHFFFAOYSA-N |
Formula | C17H34O2 |
HBA | 1 |
HBD | 1 |
MW | 270.46 |
Rotatable Bonds | 15 |
TPSA | 37.3 |
LogP | 5.94 |
Number Rings | 0 |
Number Aromatic Rings | 0 |
Heavy Atom Count | 19 |
Formal Charge | 0 |
Fraction CSP3 | 0.94 |
Exact Mass | 270.26 |
Number of Lipinski Rule Violations | 1 |
# | Species | Family | Kingdom | NCBI Taxonomy ID |
---|---|---|---|---|
1 | Juniperus phoenicea | Cupressaceae | Plantae | 61308 |
2 | Cola lateritia | Sterculiaceae | Plantae | 577684 |
Showing of synonyms
Heptadecanoic acid
506-12-7
Margaric acid
N-Heptadecanoic acid
Margarinic acid
N-Heptadecylic acid
N-Heptadecoic acid
Heptadecylic acid
NSC 3743
C17:0
MFCD00002751
Normal-heptadecanoic acid
V987Y9OZ8L
CHEBI:32365
NSC-3743
63399-94-0
EINECS 208-027-1
BRN 1781004
UNII-V987Y9OZ8L
Margarinsaeure
Margaroic acid
Daturinic acid
Daturic acid
Heptadecoic acid
AI3-36481
Heptadecanoic acic
X90
EINECS 270-298-7
Normal-heptadecanoate
Heptadecansä
Ure
Lead(2+) heptadecanoate
Heptadecanoic acid, 98%
DSSTox_CID_1596
EC 270-298-7
MARGARIC ACID [MI]
SCHEMBL5941
DSSTox_RID_78651
DSSTox_GSID_28306
Heptadecanoic acid, >=98%
4-02-00-01193 (Beilstein Handbook Reference)
WLN: QV16
CH3-[CH2]15-COOH
CHEMBL1172910
DTXSID5021596
FA 17:0a
NSC3743
EINECS 264-123-3
EINECS 266-928-5
Tox21_202550
BBL013181
LMFA01010017
S3336
STL163960
AKOS005716689
CS-W004284
FA 17:0
FH63213
HY-W004284
NSC 122836
NCGC00260099-01
AS-57021
BP-27918
BP-30092
SY010570
SDA 19-005-00
CAS-67701-03-5
H0019
NS00019727
EN300-19173
EC 266-928-5
H10748
Q902204
8EBAABCC-09B2-43FB-945D-A70E5905BFBE
Z104473032
- Nasri N, Tlili N, et al. (2011). Chemical compounds from Phoenician juniper berries (Juniperus phoenicea). Natural Product Research,2011,25(18),1733-1742. [View]
- Kamdem M, Ojo O, et al. (2022). Pentacyclic Triterpenoids, Phytosteroids and Fatty Acid Isolated from the Stem-bark of Cola lateritia K. Schum. (Sterculiaceae) of Cameroon origin; Evaluation of Their Antibacterial Activity. Arabian Journal of Chemistry, 2022, 15(1), 103506. [View]
Pubchem:
10465
Cas:
506-12-7
Gnps:
CCMSLIB00006576887
Zinc:
ZINC000024805047
Chebi:
32365
Nmrshiftdb2:
60018544
Metabolights:
MTBLC32365
Chembl:
CHEMBL1172910
Comptox:
DTXSID5021596
Pdb Ligand:
X90
CPRiL:
27302
No scaffolds available.
No bioactivities available.
Absorption
- Caco-2 (logPapp)
- -4.85
- Human Oral Bioavailability 20%
- Non-Bioavailable
- Human Intestinal Absorption
- Absorbed
- Madin-Darby Canine Kidney
- -3.99
- Human Oral Bioavailability 50%
- Non-Bioavailable
- P-Glycoprotein Inhibitor
- Non-Inhibitor
- P-Glycoprotein Substrate
- Non-Substrate
- Skin Permeability
- -2.75
Distribution
- Blood-Brain Barrier (CNS)
- -
- Blood-Brain Barrier
- Penetrable
- Fraction Unbound (Human)
- 1.38
- Plasma Protein Binding
- 43.07
- Steady State Volume of Distribution
- -
Metabolism
- Breast Cancer Resistance Protein
- Inhibitor
- CYP 1A2 Inhibitor
- Non-Inhibitor
- CYP 1A2 Substrate
- Non-Substrate
- CYP 2C19 Inhibitor
- Inhibitor
- CYP 2C19 Substrate
- Non-Substrate
- CYP 2C9 Inhibitor
- Non-Inhibitor
- CYP 2C9 Substrate
- Substrate
- CYP 2D6 Inhibitor
- Non-Inhibitor
- CYP 2D6 Substrate
- Non-Substrate
- CYP 3A4 Inhibitor
- Non-Inhibitor
- CYP 3A4 Substrate
- Non-Substrate
- OATP1B1
- Non-Inhibitor
- OATP1B3
- Non-Inhibitor
Excretion
- Clearance
- -0.02
- Organic Cation Transporter 2
- Non-Inhibitor
- Half-Life of Drug
- -
Toxicity
- AMES Mutagenesis
- Safe
- Avian
- Safe
- Bee
- Safe
- Bioconcentration Factor
- 1.07
- Biodegradation
- Toxic
- Carcinogenesis
- Safe
- Crustacean
- Toxic
- Liver Injury I (DILI)
- Toxic
- Eye Corrosion
- Toxic
- Eye Irritation
- Toxic
- Maximum Tolerated Dose
- 2.22
- Liver Injury II
- Safe
- hERG Blockers
- Safe
- Daphnia Maga
- 2.85
- Micronucleos
- Safe
- NR-AhR
- Safe
- NR-AR
- Safe
- NR-AR-LBD
- Safe
- NR-Aromatase
- Safe
- NR-ER
- Safe
- NR-ER-LBD
- Safe
- NR-GR
- Safe
- NR-PPAR-gamma
- Safe
- NR-TR
- Safe
- T. Pyriformis
- 6.3
- Rat (Acute)
- 1.32
- Rat (Chronic Oral)
- 2.37
- Fathead Minnow
- 3.92
- Respiratory Disease
- Toxic
- Skin Sensitisation
- Toxic
- SR-ARE
- Safe
- SR-ATAD5
- Safe
- SR-HSE
- Safe
- SR-MMP
- Safe
- SR-p53
- Safe
General Properties
- Boiling Point
- 352.16
- Hydration Free Energy
- -4.74
- Log(D) at pH=7.4
- 3.89
- Log(P)
- 7.62
- Log S
- -5.18
- Log(Vapor Pressure)
- -6.28
- Melting Point
- 71.37
- pKa Acid
- 4.88
- pKa Basic
- 8.69
Protein Name | UniProt ID | Entry Name | Species | #Pharmacophore Points | Probability (0.7 ≤ Tversky Score ≤ 1.0) |
---|---|---|---|---|---|
thiamine diphosphokinase | Q82ZE3 | Q82ZE3_ENTFA | Enterococcus faecalis | 3 | 0.9877 |
thiamine diphosphokinase | Q82ZE3 | Q82ZE3_ENTFA | Enterococcus faecalis | 3 | 0.9877 |
Phospholipase A2, major isoenzyme | P00592 | PA21B_PIG | Sus scrofa | 3 | 0.9358 |
Phospholipase A2, major isoenzyme | P00592 | PA21B_PIG | Sus scrofa | 3 | 0.9358 |
Methylketone synthase I | E0YCS2 | E0YCS2_SOLHA | Solanum habrochaites | 3 | 0.8747 |
Methylketone synthase I | E0YCS2 | E0YCS2_SOLHA | Solanum habrochaites | 3 | 0.8747 |
4,5:9,10-diseco-3-hydroxy-5,9,17-trioxoandrosta-1(10),2-diene-4-oate hydrolase | P9WNH5 | HSAD_MYCTU | Mycobacterium tuberculosis | 3 | 0.8537 |
4,5:9,10-diseco-3-hydroxy-5,9,17-trioxoandrosta-1(10),2-diene-4-oate hydrolase | P9WNH5 | HSAD_MYCTU | Mycobacterium tuberculosis | 3 | 0.8537 |
Sodium/potassium-transporting ATPase subunit alpha | Q4H132 | Q4H132_SQUAC | Squalus acanthias | 2 | 0.7793 |
Sodium/potassium-transporting ATPase subunit alpha | Q4H132 | Q4H132_SQUAC | Squalus acanthias | 2 | 0.7793 |
12-oxophytodienoate reductase 1 | Q9XG54 | OPR1_SOLLC | Solanum lycopersicum | 2 | 0.7527 |
12-oxophytodienoate reductase 1 | Q9XG54 | OPR1_SOLLC | Solanum lycopersicum | 2 | 0.7527 |
Streptavidin | P22629 | SAV_STRAV | Streptomyces avidinii | 2 | 0.7287 |
Streptavidin | P22629 | SAV_STRAV | Streptomyces avidinii | 2 | 0.7287 |
Abscisic acid receptor PYL9 | Q84MC7 | PYL9_ARATH | Arabidopsis thaliana | 2 | 0.7194 |
Abscisic acid receptor PYL9 | Q84MC7 | PYL9_ARATH | Arabidopsis thaliana | 2 | 0.7194 |
Abscisic acid receptor PYL2 | O80992 | PYL2_ARATH | Arabidopsis thaliana | 2 | 0.7146 |
Abscisic acid receptor PYL2 | O80992 | PYL2_ARATH | Arabidopsis thaliana | 2 | 0.7146 |
Reaction center protein L chain | P0C0Y7 | RCEH_RHOSH | Rhodobacter sphaeroides | 2 | 0.7064 |
Reaction center protein L chain | P0C0Y7 | RCEH_RHOSH | Rhodobacter sphaeroides | 2 | 0.7064 |
ADP-ribosylation factor 1 | P84077 | ARF1_HUMAN | Homo sapiens | 2 | 0.7020 |
ADP-ribosylation factor 1 | P84077 | ARF1_HUMAN | Homo sapiens | 2 | 0.7020 |
Methionine aminopeptidase 1 | P53582 | MAP11_HUMAN | Homo sapiens | 2 | 0.7015 |
Methionine aminopeptidase 1 | P53582 | MAP11_HUMAN | Homo sapiens | 2 | 0.7015 |