(R)-MTPA-ester or methyl (2E,6E,10R )-10,11-dihydroxy-7,9,11- trimethyl-2,6-dodecadienoate - Compound Card

(R)-MTPA-ester or methyl (2E,6E,10R )-10,11-dihydroxy-7,9,11- trimethyl-2,6-dodecadienoate

Select a section from the left sidebar

(R)-MTPA-ester or methyl (2E,6E,10R )-10,11-dihydroxy-7,9,11- trimethyl-2,6-dodecadienoate

Structure
Zoomed Structure
  • Family: Plantae - Annonaceae
  • Kingdom: Plantae
  • Class: Ester
Canonical Smiles COC(=O)/C=C/CC/C=C(/CC([C@H](C(O)(C)C)O)C)\C
InChI InChI=1S/C16H28O4/c1-12(9-7-6-8-10-14(17)20-5)11-13(2)15(18)16(3,4)19/h8-10,13,15,18-19H,6-7,11H2,1-5H3/b10-8+,12-9+/t13?,15-/m1/s1
InChIKey KQSXVPOADOJLQC-NLHHTSSKSA-N
Formula C16H28O4
HBA 4
HBD 2
MW 284.4
Rotatable Bonds 8
TPSA 66.76
LogP 2.6
Number Rings 0
Number Aromatic Rings 0
Heavy Atom Count 20
Formal Charge 0
Fraction CSP3 0.69
Exact Mass 284.2
Number of Lipinski Rule Violations 0
# Species Family Kingdom NCBI Taxonomy ID
1 Lettowianthus stellatus Annonaceae Plantae 489335

Showing of synonyms

  • Nkunya MH, Jonker SA, et al. (2000). Aporphinoid alkaloids and other constituents from Lettowianthus stellatus. Phytochemistry,2000,53(8),1067-1073. [View] [PubMed]

No compound-protein relationship available.

No scaffolds available.

No bioactivities available.

Absorption

Caco-2 (logPapp)
-4.56
Human Oral Bioavailability 20%
Bioavailable
Human Intestinal Absorption
Absorbed
Madin-Darby Canine Kidney
-4.050
Human Oral Bioavailability 50%
Non-Bioavailable
P-Glycoprotein Inhibitor
Inhibitor
P-Glycoprotein Substrate
Non-Substrate
Skin Permeability
-3.23

Distribution

Blood-Brain Barrier (CNS)
-
Blood-Brain Barrier
Penetrable
Fraction Unbound (Human)
0.350
Plasma Protein Binding
21.16
Steady State Volume of Distribution
-

Metabolism

Breast Cancer Resistance Protein
Non-Inhibitor
CYP 1A2 Inhibitor
Non-Inhibitor
CYP 1A2 Substrate
Non-Substrate
CYP 2C19 Inhibitor
Non-Inhibitor
CYP 2C19 Substrate
Non-Substrate
CYP 2C9 Inhibitor
Non-Inhibitor
CYP 2C9 Substrate
Non-Substrate
CYP 2D6 Inhibitor
Non-Inhibitor
CYP 2D6 Substrate
Non-Substrate
CYP 3A4 Inhibitor
Non-Inhibitor
CYP 3A4 Substrate
Non-Substrate
OATP1B1
Non-Inhibitor
OATP1B3
Non-Inhibitor

Excretion

Clearance
4.040
Organic Cation Transporter 2
Non-Inhibitor
Half-Life of Drug
-

Toxicity

AMES Mutagenesis
Safe
Avian
Safe
Bee
Toxic
Bioconcentration Factor
0.690
Biodegradation
Toxic
Carcinogenesis
Safe
Crustacean
Toxic
Liver Injury I (DILI)
Safe
Eye Corrosion
Safe
Eye Irritation
Toxic
Maximum Tolerated Dose
0.210
Liver Injury II
Safe
hERG Blockers
Safe
Daphnia Maga
4.460
Micronucleos
Safe
NR-AhR
Safe
NR-AR
Safe
NR-AR-LBD
Safe
NR-Aromatase
Safe
NR-ER
Safe
NR-ER-LBD
Safe
NR-GR
Safe
NR-PPAR-gamma
Safe
NR-TR
Safe
T. Pyriformis
1.970
Rat (Acute)
1.810
Rat (Chronic Oral)
2.030
Fathead Minnow
4.590
Respiratory Disease
Toxic
Skin Sensitisation
Toxic
SR-ARE
Safe
SR-ATAD5
Safe
SR-HSE
Safe
SR-MMP
Safe
SR-p53
Safe

General Properties

Boiling Point
321.170
Hydration Free Energy
-8.420
Log(D) at pH=7.4
2.020
Log(P)
2.97
Log S
-3.29
Log(Vapor Pressure)
-5.07
Melting Point
49.62
pKa Acid
10.93
pKa Basic
5.72
Protein Name UniProt ID Entry Name Species #Pharmacophore Points Probability (0.7 ≤ Tversky Score ≤ 1.0)
Mycinamicin III 3''-O-methyltransferase Q49492 MYCF_MICGR Micromonospora griseorubida 2 0.8952
Mycinamicin III 3''-O-methyltransferase Q49492 MYCF_MICGR Micromonospora griseorubida 2 0.8952
Ferrochelatase, mitochondrial P22830 HEMH_HUMAN Homo sapiens 3 0.8939
Ferrochelatase, mitochondrial P22830 HEMH_HUMAN Homo sapiens 3 0.8939
Quorum-sensing transcriptional activator Q8XBD0 Q8XBD0_ECO57 Escherichia coli O157:H7 3 0.8924
Quorum-sensing transcriptional activator Q8XBD0 Q8XBD0_ECO57 Escherichia coli O157:H7 3 0.8924
Pentaerythritol tetranitrate reductase P71278 P71278_ENTCL Enterobacter cloacae 3 0.8918
Pentaerythritol tetranitrate reductase P71278 P71278_ENTCL Enterobacter cloacae 3 0.8918
Sex hormone-binding globulin P04278 SHBG_HUMAN Homo sapiens 3 0.8908
Sex hormone-binding globulin P04278 SHBG_HUMAN Homo sapiens 3 0.8908
Integrin alpha-L P20701 ITAL_HUMAN Homo sapiens 3 0.8781
Integrin alpha-L P20701 ITAL_HUMAN Homo sapiens 3 0.8781
Aldo-keto reductase family 1 member D1 P51857 AK1D1_HUMAN Homo sapiens 3 0.8764
Aldo-keto reductase family 1 member D1 P51857 AK1D1_HUMAN Homo sapiens 3 0.8764
Bacteriorhodopsin P02945 BACR_HALSA Halobacterium salinarum 3 0.8743
Bacteriorhodopsin P02945 BACR_HALSA Halobacterium salinarum 3 0.8743
Mycinamicin III 3''-O-methyltransferase Q49492 MYCF_MICGR Micromonospora griseorubida 2 0.8733
Mycinamicin III 3''-O-methyltransferase Q49492 MYCF_MICGR Micromonospora griseorubida 2 0.8733
Aldo-keto reductase family 1 member D1 P51857 AK1D1_HUMAN Homo sapiens 3 0.8665
Aldo-keto reductase family 1 member D1 P51857 AK1D1_HUMAN Homo sapiens 3 0.8665
Photosynthetic reaction center cytochrome c subunit P07173 CYCR_BLAVI Blastochloris viridis 3 0.8640
Photosynthetic reaction center cytochrome c subunit P07173 CYCR_BLAVI Blastochloris viridis 3 0.8640
Vitamin D3 receptor P13053 VDR_RAT Rattus norvegicus 3 0.8565
Vitamin D3 receptor P13053 VDR_RAT Rattus norvegicus 3 0.8565
CmeR Q7B8P6 Q7B8P6_CAMJU Campylobacter jejuni 3 0.8548
CmeR Q7B8P6 Q7B8P6_CAMJU Campylobacter jejuni 3 0.8548
Beta-lactoglobulin P02754 LACB_BOVIN Bos taurus 3 0.8503
Beta-lactoglobulin P02754 LACB_BOVIN Bos taurus 3 0.8503
Aldo-keto reductase family 1 member C2 P52895 AK1C2_HUMAN Homo sapiens 3 0.8493
Aldo-keto reductase family 1 member C2 P52895 AK1C2_HUMAN Homo sapiens 3 0.8493
11-beta-hydroxysteroid dehydrogenase 1 P50172 DHI1_MOUSE Mus musculus 3 0.8378
11-beta-hydroxysteroid dehydrogenase 1 P50172 DHI1_MOUSE Mus musculus 3 0.8378
Sex hormone-binding globulin P04278 SHBG_HUMAN Homo sapiens 3 0.8370
Sex hormone-binding globulin P04278 SHBG_HUMAN Homo sapiens 3 0.8370
Methylketone synthase I E0YCS2 E0YCS2_SOLHA Solanum habrochaites 3 0.8352
Methylketone synthase I E0YCS2 E0YCS2_SOLHA Solanum habrochaites 3 0.8352
Sulfotransferase 2B1 O00204 ST2B1_HUMAN Homo sapiens 2 0.8283
Sulfotransferase 2B1 O00204 ST2B1_HUMAN Homo sapiens 2 0.8283
Aldo-keto reductase family 1 member C2 P52895 AK1C2_HUMAN Homo sapiens 3 0.8266
Aldo-keto reductase family 1 member C2 P52895 AK1C2_HUMAN Homo sapiens 3 0.8266
Retinoic acid receptor RXR-alpha P19793 RXRA_HUMAN Homo sapiens 3 0.8209
Retinoic acid receptor RXR-alpha P19793 RXRA_HUMAN Homo sapiens 3 0.8209
Abscisic acid receptor PYL10 Q8H1R0 PYL10_ARATH Arabidopsis thaliana 3 0.8142
Abscisic acid receptor PYL10 Q8H1R0 PYL10_ARATH Arabidopsis thaliana 3 0.8142
Corticosteroid-binding globulin P08185 CBG_HUMAN Homo sapiens 3 0.8124
Corticosteroid-binding globulin P08185 CBG_HUMAN Homo sapiens 3 0.8124
Soluble acetylcholine receptor Q8WSF8 Q8WSF8_APLCA Aplysia californica 3 0.8108
Soluble acetylcholine receptor Q8WSF8 Q8WSF8_APLCA Aplysia californica 3 0.8108
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 P04191 AT2A1_RABIT Oryctolagus cuniculus 3 0.8106
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 P04191 AT2A1_RABIT Oryctolagus cuniculus 3 0.8106
Sex hormone-binding globulin P04278 SHBG_HUMAN Homo sapiens 3 0.8099
Sex hormone-binding globulin P04278 SHBG_HUMAN Homo sapiens 3 0.8099
Retinoic acid receptor RXR-alpha P19793 RXRA_HUMAN Homo sapiens 3 0.8089
Retinoic acid receptor RXR-alpha P19793 RXRA_HUMAN Homo sapiens 3 0.8089
Acetylcholinesterase P04058 ACES_TETCF Tetronarce californica 3 0.8080
Acetylcholinesterase P04058 ACES_TETCF Tetronarce californica 3 0.8080
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 P04191 AT2A1_RABIT Oryctolagus cuniculus 3 0.8064
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 P04191 AT2A1_RABIT Oryctolagus cuniculus 3 0.8064
Mineralocorticoid receptor P08235 MCR_HUMAN Homo sapiens 3 0.8061
Mineralocorticoid receptor P08235 MCR_HUMAN Homo sapiens 3 0.8061
Retinoic acid receptor RXR-alpha P19793 RXRA_HUMAN Homo sapiens 3 0.8049
Retinoic acid receptor RXR-alpha P19793 RXRA_HUMAN Homo sapiens 3 0.8049
Lactoylglutathione lyase Q9CPU0 LGUL_MOUSE Mus musculus 2 0.8021
Lactoylglutathione lyase Q9CPU0 LGUL_MOUSE Mus musculus 2 0.8021
Mineralocorticoid receptor P08235 MCR_HUMAN Homo sapiens 3 0.8008
Mineralocorticoid receptor P08235 MCR_HUMAN Homo sapiens 3 0.8008
Rhodopsin P02699 OPSD_BOVIN Bos taurus 3 0.7993
Rhodopsin P02699 OPSD_BOVIN Bos taurus 3 0.7993
Retinoic acid receptor RXR-alpha P19793 RXRA_HUMAN Homo sapiens 3 0.7973
Retinoic acid receptor RXR-alpha P19793 RXRA_HUMAN Homo sapiens 3 0.7973
Mineralocorticoid receptor P08235 MCR_HUMAN Homo sapiens 3 0.7960
Mineralocorticoid receptor P08235 MCR_HUMAN Homo sapiens 3 0.7960
Abscisic acid receptor PYL3 Q9SSM7 PYL3_ARATH Arabidopsis thaliana 3 0.7942
Abscisic acid receptor PYL3 Q9SSM7 PYL3_ARATH Arabidopsis thaliana 3 0.7942
Aldo-keto reductase family 1 member D1 P51857 AK1D1_HUMAN Homo sapiens 2 0.7926
Aldo-keto reductase family 1 member D1 P51857 AK1D1_HUMAN Homo sapiens 2 0.7926
Abscisic acid receptor PYR1 O49686 PYR1_ARATH Arabidopsis thaliana 3 0.7903
Abscisic acid receptor PYR1 O49686 PYR1_ARATH Arabidopsis thaliana 3 0.7903
Aldo-keto reductase family 1 member D1 P51857 AK1D1_HUMAN Homo sapiens 3 0.7881
Aldo-keto reductase family 1 member D1 P51857 AK1D1_HUMAN Homo sapiens 3 0.7881
Aldo-keto reductase family 1 member C2 P52895 AK1C2_HUMAN Homo sapiens 3 0.7869
Aldo-keto reductase family 1 member C2 P52895 AK1C2_HUMAN Homo sapiens 3 0.7869
Retinoic acid receptor RXR-alpha P19793 RXRA_HUMAN Homo sapiens 3 0.7867
Retinoic acid receptor RXR-alpha P19793 RXRA_HUMAN Homo sapiens 3 0.7867
Retinoic acid receptor RXR-alpha P19793 RXRA_HUMAN Homo sapiens 3 0.7861
Retinoic acid receptor RXR-alpha P19793 RXRA_HUMAN Homo sapiens 3 0.7861
Epoxide hydrolase Q41415 Q41415_SOLTU Solanum tuberosum 3 0.7820
Epoxide hydrolase Q41415 Q41415_SOLTU Solanum tuberosum 3 0.7820
Nuclear receptor subfamily 1 group I member 2 O75469 NR1I2_HUMAN Homo sapiens 3 0.7801
Nuclear receptor subfamily 1 group I member 2 O75469 NR1I2_HUMAN Homo sapiens 3 0.7801
Retinoic acid receptor beta P10826 RARB_HUMAN Homo sapiens 3 0.7797
Retinoic acid receptor beta P10826 RARB_HUMAN Homo sapiens 3 0.7797
Peptidyl-prolyl cis-trans isomerase FKBP1A P62942 FKB1A_HUMAN Homo sapiens 3 0.7774
Peptidyl-prolyl cis-trans isomerase FKBP1A P62942 FKB1A_HUMAN Homo sapiens 3 0.7774
Prostaglandin reductase 2 Q8N8N7 PTGR2_HUMAN Homo sapiens 2 0.7765
Prostaglandin reductase 2 Q8N8N7 PTGR2_HUMAN Homo sapiens 2 0.7765
Aldo-keto reductase family 1 member C1 Q04828 AK1C1_HUMAN Homo sapiens 3 0.7763
Aldo-keto reductase family 1 member C1 Q04828 AK1C1_HUMAN Homo sapiens 3 0.7763
CmeR Q7B8P6 Q7B8P6_CAMJU Campylobacter jejuni 2 0.7746
CmeR Q7B8P6 Q7B8P6_CAMJU Campylobacter jejuni 2 0.7746
Aldo-keto reductase family 1 member D1 P51857 AK1D1_HUMAN Homo sapiens 2 0.7720
Aldo-keto reductase family 1 member D1 P51857 AK1D1_HUMAN Homo sapiens 2 0.7720
Aldo-keto reductase family 1 member D1 P51857 AK1D1_HUMAN Homo sapiens 2 0.7704
Aldo-keto reductase family 1 member D1 P51857 AK1D1_HUMAN Homo sapiens 2 0.7704
Nuclear receptor ROR-beta P45446 RORB_RAT Rattus norvegicus 2 0.7700
Nuclear receptor ROR-beta P45446 RORB_RAT Rattus norvegicus 2 0.7700
Thyroid hormone receptor alpha P04625 THA_CHICK Gallus gallus 3 0.7695
Thyroid hormone receptor alpha P04625 THA_CHICK Gallus gallus 3 0.7695
Aldo-keto reductase family 1 member D1 P51857 AK1D1_HUMAN Homo sapiens 3 0.7687
Aldo-keto reductase family 1 member D1 P51857 AK1D1_HUMAN Homo sapiens 3 0.7687
ADP-ribosylation factor 1 P84080 ARF1_BOVIN Bos taurus 3 0.7682
ADP-ribosylation factor 1 P84080 ARF1_BOVIN Bos taurus 3 0.7682
Retinoic acid receptor RXR-alpha P28700 RXRA_MOUSE Mus musculus 3 0.7678
Retinoic acid receptor RXR-alpha P28700 RXRA_MOUSE Mus musculus 3 0.7678
Aldo-keto reductase family 1 member C2 P52895 AK1C2_HUMAN Homo sapiens 2 0.7673
Aldo-keto reductase family 1 member C2 P52895 AK1C2_HUMAN Homo sapiens 2 0.7673
3-alpha-hydroxysteroid dehydrogenase P23457 DIDH_RAT Rattus norvegicus 2 0.7669
3-alpha-hydroxysteroid dehydrogenase P23457 DIDH_RAT Rattus norvegicus 2 0.7669
Steroid Delta-isomerase P07445 SDIS_PSEPU Pseudomonas putida 2 0.7668
Acetylcholinesterase P21836 ACES_MOUSE Mus musculus 3 0.7668
Steroid Delta-isomerase P07445 SDIS_PSEPU Pseudomonas putida 2 0.7668
Acetylcholinesterase P21836 ACES_MOUSE Mus musculus 3 0.7668
Ferrochelatase, mitochondrial P22830 HEMH_HUMAN Homo sapiens 3 0.7654
Ferrochelatase, mitochondrial P22830 HEMH_HUMAN Homo sapiens 3 0.7654
Aldo-keto reductase family 1 member D1 P51857 AK1D1_HUMAN Homo sapiens 2 0.7645
Aldo-keto reductase family 1 member D1 P51857 AK1D1_HUMAN Homo sapiens 2 0.7645
Pentaerythritol tetranitrate reductase P71278 P71278_ENTCL Enterobacter cloacae 3 0.7639
Pentaerythritol tetranitrate reductase P71278 P71278_ENTCL Enterobacter cloacae 3 0.7639
Aldo-keto reductase family 1 member C2 P52895 AK1C2_HUMAN Homo sapiens 2 0.7638
Aldo-keto reductase family 1 member C2 P52895 AK1C2_HUMAN Homo sapiens 2 0.7638
Beta-1 adrenergic receptor P07700 ADRB1_MELGA Meleagris gallopavo 3 0.7637
Beta-1 adrenergic receptor P07700 ADRB1_MELGA Meleagris gallopavo 3 0.7637
Sulfotransferase 2B1 O00204 ST2B1_HUMAN Homo sapiens 2 0.7619
Sulfotransferase 2B1 O00204 ST2B1_HUMAN Homo sapiens 2 0.7619
Beta-1 adrenergic receptor P07700 ADRB1_MELGA Meleagris gallopavo 2 0.7610
Beta-1 adrenergic receptor P07700 ADRB1_MELGA Meleagris gallopavo 2 0.7610
Steroid 21-hydroxylase P08686 CP21A_HUMAN Homo sapiens 2 0.7601
Steroid 21-hydroxylase P08686 CP21A_HUMAN Homo sapiens 2 0.7601
Sulfotransferase 2A1 Q06520 ST2A1_HUMAN Homo sapiens 2 0.7599
Sulfotransferase 2A1 Q06520 ST2A1_HUMAN Homo sapiens 2 0.7599
Nuclear receptor ROR-gamma P51449 RORG_HUMAN Homo sapiens 2 0.7563
Nuclear receptor ROR-gamma P51449 RORG_HUMAN Homo sapiens 2 0.7563
Pentaerythritol tetranitrate reductase P71278 P71278_ENTCL Enterobacter cloacae 3 0.7553
Pentaerythritol tetranitrate reductase P71278 P71278_ENTCL Enterobacter cloacae 3 0.7553
Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial Q0QF01 SDHA_PIG Sus scrofa 2 0.7536
Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial Q0QF01 SDHA_PIG Sus scrofa 2 0.7536
Androgen receptor P10275 ANDR_HUMAN Homo sapiens 4 0.7521
Androgen receptor P10275 ANDR_HUMAN Homo sapiens 4 0.7521
Aldo-keto reductase family 1 member D1 P51857 AK1D1_HUMAN Homo sapiens 2 0.7514
Aldo-keto reductase family 1 member D1 P51857 AK1D1_HUMAN Homo sapiens 2 0.7514
Phospholipase A2, major isoenzyme P00592 PA21B_PIG Sus scrofa 3 0.7498
Phospholipase A2, major isoenzyme P00592 PA21B_PIG Sus scrofa 3 0.7498
Sex hormone-binding globulin P04278 SHBG_HUMAN Homo sapiens 3 0.7490
Sex hormone-binding globulin P04278 SHBG_HUMAN Homo sapiens 3 0.7490
Neocarzinostatin P0A3R9 NCZS_STRCZ Streptomyces carzinostaticus 2 0.7477
Neocarzinostatin P0A3R9 NCZS_STRCZ Streptomyces carzinostaticus 2 0.7477
Fatty acid-binding protein, liver P80226 FABPL_CHICK Gallus gallus 2 0.7471
Fatty acid-binding protein, liver P80226 FABPL_CHICK Gallus gallus 2 0.7471
Androgen receptor P10275 ANDR_HUMAN Homo sapiens 3 0.7450
Androgen receptor P10275 ANDR_HUMAN Homo sapiens 3 0.7450
Steroid Delta-isomerase P00947 SDIS_COMTE Comamonas testosteroni 2 0.7431
Steroid Delta-isomerase P00947 SDIS_COMTE Comamonas testosteroni 2 0.7431
Ferrochelatase, mitochondrial P22830 HEMH_HUMAN Homo sapiens 2 0.7424
Ferrochelatase, mitochondrial P22830 HEMH_HUMAN Homo sapiens 2 0.7424
Ferrochelatase, mitochondrial P22830 HEMH_HUMAN Homo sapiens 3 0.7410
Ferrochelatase, mitochondrial P22830 HEMH_HUMAN Homo sapiens 3 0.7410
Beta-1 adrenergic receptor P07700 ADRB1_MELGA Meleagris gallopavo 2 0.7401
Beta-1 adrenergic receptor P07700 ADRB1_MELGA Meleagris gallopavo 2 0.7401
Abscisic acid receptor PYL2 O80992 PYL2_ARATH Arabidopsis thaliana 2 0.7397
Abscisic acid receptor PYL2 O80992 PYL2_ARATH Arabidopsis thaliana 2 0.7397
17-beta-hydroxysteroid dehydrogenase type 1 P14061 DHB1_HUMAN Homo sapiens 2 0.7396
17-beta-hydroxysteroid dehydrogenase type 1 P14061 DHB1_HUMAN Homo sapiens 2 0.7396
Cytochrome P450 monooxygenase Q5YNS8 Q5YNS8_NOCFA Nocardia farcinica 2 0.7387
Cytochrome P450 monooxygenase Q5YNS8 Q5YNS8_NOCFA Nocardia farcinica 2 0.7387
Peroxisome proliferator-activated receptor gamma P37231 PPARG_HUMAN Homo sapiens 2 0.7380
Peroxisome proliferator-activated receptor gamma P37231 PPARG_HUMAN Homo sapiens 2 0.7380
Nuclear receptor subfamily 1 group I member 3 O35627 NR1I3_MOUSE Mus musculus 2 0.7349
Nuclear receptor subfamily 1 group I member 3 O35627 NR1I3_MOUSE Mus musculus 2 0.7349
Camphor 5-monooxygenase P00183 CPXA_PSEPU Pseudomonas putida 3 0.7345
Camphor 5-monooxygenase P00183 CPXA_PSEPU Pseudomonas putida 3 0.7345
Aldo-keto reductase family 1 member D1 P51857 AK1D1_HUMAN Homo sapiens 2 0.7331
Aldo-keto reductase family 1 member D1 P51857 AK1D1_HUMAN Homo sapiens 2 0.7331
Soluble cytochrome b562 P0ABE7 C562_ECOLX Escherichia coli 2 0.7326
Soluble cytochrome b562 P0ABE7 C562_ECOLX Escherichia coli 2 0.7326
Vitamin D-binding protein P02774 VTDB_HUMAN Homo sapiens 2 0.7305
Vitamin D-binding protein P02774 VTDB_HUMAN Homo sapiens 2 0.7305
Pentaerythritol tetranitrate reductase P71278 P71278_ENTCL Enterobacter cloacae 3 0.7273
Pentaerythritol tetranitrate reductase P71278 P71278_ENTCL Enterobacter cloacae 3 0.7273
Androgen receptor P10275 ANDR_HUMAN Homo sapiens 3 0.7270
Androgen receptor P10275 ANDR_HUMAN Homo sapiens 3 0.7270
Phospholipase A2, major isoenzyme P00592 PA21B_PIG Sus scrofa 3 0.7268
Phospholipase A2, major isoenzyme P00592 PA21B_PIG Sus scrofa 3 0.7268
Abscisic acid receptor PYL3 Q9SSM7 PYL3_ARATH Arabidopsis thaliana 2 0.7266
Abscisic acid receptor PYL3 Q9SSM7 PYL3_ARATH Arabidopsis thaliana 2 0.7266
Probable NDP-rhamnosyltransferase Q9ALM8 Q9ALM8_SACSN Saccharopolyspora spinosa 3 0.7265
Probable NDP-rhamnosyltransferase Q9ALM8 Q9ALM8_SACSN Saccharopolyspora spinosa 3 0.7265
Abscisic acid receptor PYL9 Q84MC7 PYL9_ARATH Arabidopsis thaliana 3 0.7259
Abscisic acid receptor PYL9 Q84MC7 PYL9_ARATH Arabidopsis thaliana 3 0.7259
Progesterone receptor P06401 PRGR_HUMAN Homo sapiens 2 0.7252
Progesterone receptor P06401 PRGR_HUMAN Homo sapiens 2 0.7252
Progesterone receptor P06401 PRGR_HUMAN Homo sapiens 3 0.7247
Progesterone receptor P06401 PRGR_HUMAN Homo sapiens 3 0.7247
4,4'-diapophytoene synthase A9JQL9 CRTM_STAAU Staphylococcus aureus 2 0.7237
4,4'-diapophytoene synthase A9JQL9 CRTM_STAAU Staphylococcus aureus 2 0.7237
Abscisic acid receptor PYL2 O80992 PYL2_ARATH Arabidopsis thaliana 3 0.7203
Abscisic acid receptor PYL2 O80992 PYL2_ARATH Arabidopsis thaliana 3 0.7203
Retinoic acid receptor RXR-alpha P19793 RXRA_HUMAN Homo sapiens 2 0.7192
Retinoic acid receptor RXR-alpha P19793 RXRA_HUMAN Homo sapiens 2 0.7192
Abscisic acid receptor PYL3 Q9SSM7 PYL3_ARATH Arabidopsis thaliana 3 0.7184
Abscisic acid receptor PYL3 Q9SSM7 PYL3_ARATH Arabidopsis thaliana 3 0.7184
Type IV / VI secretion system DotU domain-containing protein Q9KN50 Q9KN50_VIBCH Vibrio cholerae serotype O1 2 0.7158
Type IV / VI secretion system DotU domain-containing protein Q9KN50 Q9KN50_VIBCH Vibrio cholerae serotype O1 2 0.7158
Trichodiene synthase P13513 TRI5_FUSSP Fusarium sporotrichioides 2 0.7147
Trichodiene synthase P13513 TRI5_FUSSP Fusarium sporotrichioides 2 0.7147
Multidrug transporter MdfA P0AEY8 MDFA_ECOLI Escherichia coli 3 0.7142
Multidrug transporter MdfA P0AEY8 MDFA_ECOLI Escherichia coli 3 0.7142
Abscisic acid receptor PYL2 O80992 PYL2_ARATH Arabidopsis thaliana 3 0.7134
Abscisic acid receptor PYL2 O80992 PYL2_ARATH Arabidopsis thaliana 3 0.7134
Adenylate cyclase type 5 P30803 ADCY5_CANLF Canis lupus familiaris 4 0.7130
Adenylate cyclase type 5 P30803 ADCY5_CANLF Canis lupus familiaris 4 0.7130
Cytochrome P450 monooxygenase Q5YNS8 Q5YNS8_NOCFA Nocardia farcinica 2 0.7129
Cytochrome P450 monooxygenase Q5YNS8 Q5YNS8_NOCFA Nocardia farcinica 2 0.7129
Alcohol dehydrogenase 1C P00326 ADH1G_HUMAN Homo sapiens 3 0.7123
Alcohol dehydrogenase 1C P00326 ADH1G_HUMAN Homo sapiens 3 0.7123
Corticosteroid-binding globulin P31211 CBG_RAT Rattus norvegicus 3 0.7110
Corticosteroid-binding globulin P31211 CBG_RAT Rattus norvegicus 3 0.7110
Gastrotropin P51161 FABP6_HUMAN Homo sapiens 3 0.7105
Gastrotropin P51161 FABP6_HUMAN Homo sapiens 3 0.7105
Adenylate cyclase type 5 P30803 ADCY5_CANLF Canis lupus familiaris 3 0.7098
Adenylate cyclase type 5 P30803 ADCY5_CANLF Canis lupus familiaris 3 0.7098
Progesterone receptor P06401 PRGR_HUMAN Homo sapiens 4 0.7094
Progesterone receptor P06401 PRGR_HUMAN Homo sapiens 4 0.7094
Adenylate cyclase type 5 P30803 ADCY5_CANLF Canis lupus familiaris 4 0.7086
Adenylate cyclase type 5 P30803 ADCY5_CANLF Canis lupus familiaris 4 0.7086
Prolyl tripeptidyl peptidase Q7MUW6 PTP_PORGI Porphyromonas gingivalis 2 0.7043
Prolyl tripeptidyl peptidase Q7MUW6 PTP_PORGI Porphyromonas gingivalis 2 0.7043
Abscisic acid receptor PYL9 Q5Z8S0 PYL9_ORYSJ Oryza sativa subsp. japonica 3 0.7024
Abscisic acid receptor PYL9 Q5Z8S0 PYL9_ORYSJ Oryza sativa subsp. japonica 3 0.7024
Adenylate cyclase type 5 P30803 ADCY5_CANLF Canis lupus familiaris 4 0.7019
Adenylate cyclase type 5 P30803 ADCY5_CANLF Canis lupus familiaris 4 0.7019
Aromatase P11511 CP19A_HUMAN Homo sapiens 2 0.7018
Aromatase P11511 CP19A_HUMAN Homo sapiens 2 0.7018
NPC intracellular cholesterol transporter 1 O15118 NPC1_HUMAN Homo sapiens 2 0.7015
Phospholipase A2, major isoenzyme P00592 PA21B_PIG Sus scrofa 3 0.7015
NPC intracellular cholesterol transporter 1 O15118 NPC1_HUMAN Homo sapiens 2 0.7015
Phospholipase A2, major isoenzyme P00592 PA21B_PIG Sus scrofa 3 0.7015
17-beta-hydroxysteroid dehydrogenase type 1 P14061 DHB1_HUMAN Homo sapiens 3 0.7014
17-beta-hydroxysteroid dehydrogenase type 1 P14061 DHB1_HUMAN Homo sapiens 3 0.7014
Retinol dehydratase Q26490 Q26490_SPOFR Spodoptera frugiperda 3 0.7004
Retinol dehydratase Q26490 Q26490_SPOFR Spodoptera frugiperda 3 0.7004

Download SDF