(-)-6-styryl-7,8-dihydroxy-4- methoxypyran-2-one - Compound Card

(-)-6-styryl-7,8-dihydroxy-4- methoxypyran-2-one

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(-)-6-styryl-7,8-dihydroxy-4- methoxypyran-2-one

Structure
Zoomed Structure
  • Family: Annonaceae
  • Kingdom: Plantae
  • Class: Phenanthrenoid
    • Subclass: Pyrone
Canonical Smiles COc1cc(oc(=O)c1)[C@H]([C@H](c1ccccc1)O)O
InChI InChI=1S/C14H14O5/c1-18-10-7-11(19-12(15)8-10)14(17)13(16)9-5-3-2-4-6-9/h2-8,13-14,16-17H,1H3/t13-,14+/m0/s1
InChIKey PLPIXLSRTIVHDP-UONOGXRCSA-N
Formula C14H14O5
HBA 5
HBD 2
MW 262.26
Rotatable Bonds 4
TPSA 79.9
LogP 1.42
Number Rings 2
Number Aromatic Rings 2
Heavy Atom Count 19
Formal Charge 0
Fraction CSP3 0.21
Exact Mass 262.08
Number of Lipinski Rule Violations 0
# Species Family Kingdom NCBI Taxonomy ID
1 Ophrypetalum odoratum Annonaceae Plantae 489344

Showing of synonyms

  • Malebo HM, Kihampa C, et al. (2014). Antifungal enantiomeric styrylpyrones from Sanrafaelia ruffonammari and Ophrypetalum odoratum. Natural Products and Bioprospecting,2014,4(2),129-133. [View] [PubMed]

No compound-protein relationship available.

Structure

SMILES: c1ccccc1CCc2cccc(=O)o2

Level: 1

Mol. Weight: 200.24 g/mol

Structure

SMILES: O=c1cccco1

Level: 0

Mol. Weight: 96.08 g/mol

Structure

SMILES: c1ccccc1

Level: 0

Mol. Weight: 78.11 g/mol

Antifungal

Absorption

Caco-2 (logPapp)
-4.89
Human Oral Bioavailability 20%
Bioavailable
Human Intestinal Absorption
Absorbed
Madin-Darby Canine Kidney
-3.780
Human Oral Bioavailability 50%
Bioavailable
P-Glycoprotein Inhibitor
Non-Inhibitor
P-Glycoprotein Substrate
Non-Substrate
Skin Permeability
-2.67

Distribution

Blood-Brain Barrier (CNS)
-
Blood-Brain Barrier
Penetrable
Fraction Unbound (Human)
0.780
Plasma Protein Binding
69.8
Steady State Volume of Distribution
-

Metabolism

Breast Cancer Resistance Protein
Non-Inhibitor
CYP 1A2 Inhibitor
Non-Inhibitor
CYP 1A2 Substrate
Non-Substrate
CYP 2C19 Inhibitor
Non-Inhibitor
CYP 2C19 Substrate
Non-Substrate
CYP 2C9 Inhibitor
Non-Inhibitor
CYP 2C9 Substrate
Substrate
CYP 2D6 Inhibitor
Non-Inhibitor
CYP 2D6 Substrate
Non-Substrate
CYP 3A4 Inhibitor
Non-Inhibitor
CYP 3A4 Substrate
Non-Substrate
OATP1B1
Non-Inhibitor
OATP1B3
Non-Inhibitor

Excretion

Clearance
2.940
Organic Cation Transporter 2
Non-Inhibitor
Half-Life of Drug
-

Toxicity

AMES Mutagenesis
Safe
Avian
Safe
Bee
Safe
Bioconcentration Factor
0.100
Biodegradation
Safe
Carcinogenesis
Safe
Crustacean
Safe
Liver Injury I (DILI)
Safe
Eye Corrosion
Safe
Eye Irritation
Safe
Maximum Tolerated Dose
0.660
Liver Injury II
Toxic
hERG Blockers
Safe
Daphnia Maga
3.920
Micronucleos
Toxic
NR-AhR
Safe
NR-AR
Safe
NR-AR-LBD
Safe
NR-Aromatase
Safe
NR-ER
Safe
NR-ER-LBD
Safe
NR-GR
Safe
NR-PPAR-gamma
Safe
NR-TR
Safe
T. Pyriformis
1.070
Rat (Acute)
2.000
Rat (Chronic Oral)
2.040
Fathead Minnow
4.050
Respiratory Disease
Safe
Skin Sensitisation
Safe
SR-ARE
Safe
SR-ATAD5
Safe
SR-HSE
Safe
SR-MMP
Safe
SR-p53
Safe

General Properties

Boiling Point
360.020
Hydration Free Energy
-11.530
Log(D) at pH=7.4
0.860
Log(P)
0.14
Log S
-1.99
Log(Vapor Pressure)
-7.12
Melting Point
121.21
pKa Acid
7.93
pKa Basic
1.08
Protein Name UniProt ID Entry Name Species #Pharmacophore Points Probability (0.7 ≤ Tversky Score ≤ 1.0)
Ribosomal small subunit pseudouridine synthase A P0AA43 RSUA_ECOLI Escherichia coli 3 0.9824
Ribosomal small subunit pseudouridine synthase A P0AA43 RSUA_ECOLI Escherichia coli 3 0.9824
Acetolactate synthase, chloroplastic P17597 ILVB_ARATH Arabidopsis thaliana 3 0.9360
Acetolactate synthase, chloroplastic P17597 ILVB_ARATH Arabidopsis thaliana 3 0.9360
Mycocyclosin synthase P9WPP7 CP121_MYCTU Mycobacterium tuberculosis 3 0.9340
Mycocyclosin synthase P9WPP7 CP121_MYCTU Mycobacterium tuberculosis 3 0.9340
Riboflavin synthase P0AFU8 RISA_ECOLI Escherichia coli 4 0.9306
Riboflavin synthase P0AFU8 RISA_ECOLI Escherichia coli 4 0.9306
Abscisic acid receptor PYL2 O80992 PYL2_ARATH Arabidopsis thaliana 3 0.9232
Abscisic acid receptor PYL2 O80992 PYL2_ARATH Arabidopsis thaliana 3 0.9232
3',5'-cyclic-AMP phosphodiesterase 4D Q08499 PDE4D_HUMAN Homo sapiens 3 0.9181
3',5'-cyclic-AMP phosphodiesterase 4D Q08499 PDE4D_HUMAN Homo sapiens 3 0.9181
Lactoperoxidase P80025 PERL_BOVIN Bos taurus 3 0.9159
Lactoperoxidase P80025 PERL_BOVIN Bos taurus 3 0.9159
Beta-secretase 1 P56817 BACE1_HUMAN Homo sapiens 3 0.9130
Beta-secretase 1 P56817 BACE1_HUMAN Homo sapiens 3 0.9130
NAD-capped RNA hydrolase NudC P32664 NUDC_ECOLI Escherichia coli 3 0.9095
NAD-capped RNA hydrolase NudC P32664 NUDC_ECOLI Escherichia coli 3 0.9095
Lactotransferrin P24627 TRFL_BOVIN Bos taurus 3 0.9056
Lactotransferrin P24627 TRFL_BOVIN Bos taurus 3 0.9056
L-lactate dehydrogenase A chain P04642 LDHA_RAT Rattus norvegicus 3 0.9035
L-lactate dehydrogenase A chain P04642 LDHA_RAT Rattus norvegicus 3 0.9035
Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase Q9TQS6 DHDH_MACFA Macaca fascicularis 3 0.8981
Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase Q9TQS6 DHDH_MACFA Macaca fascicularis 3 0.8981
Putative HMP/thiamine-binding protein YkoF O34911 YKOF_BACSU Bacillus subtilis 3 0.8952
Putative HMP/thiamine-binding protein YkoF O34911 YKOF_BACSU Bacillus subtilis 3 0.8952
Chitinase A Q9AMP1 Q9AMP1_VIBHA Vibrio harveyi 3 0.8932
Chitinase A Q9AMP1 Q9AMP1_VIBHA Vibrio harveyi 3 0.8932
Proton-gated ion channel Q7NDN8 GLIC_GLOVI Gloeobacter violaceus 3 0.8919
Proton-gated ion channel Q7NDN8 GLIC_GLOVI Gloeobacter violaceus 3 0.8919
Rhodopsin kinase GRK1 P28327 GRK1_BOVIN Bos taurus 3 0.8881
Rhodopsin kinase GRK1 P28327 GRK1_BOVIN Bos taurus 3 0.8881
Mitogen-activated protein kinase 10 P53779 MK10_HUMAN Homo sapiens 3 0.8878
Mitogen-activated protein kinase 10 P53779 MK10_HUMAN Homo sapiens 3 0.8878
Norsolorinic acid synthase Q12053 AFLC_ASPPU Aspergillus parasiticus 3 0.8816
Norsolorinic acid synthase Q12053 AFLC_ASPPU Aspergillus parasiticus 3 0.8816
Mitogen-activated protein kinase 14 Q16539 MK14_HUMAN Homo sapiens 3 0.8810
Mitogen-activated protein kinase 14 Q16539 MK14_HUMAN Homo sapiens 3 0.8810
Beta-lactamase Q9L5C8 Q9L5C8_ECOLX Escherichia coli 3 0.8782
Beta-lactamase Q9L5C8 Q9L5C8_ECOLX Escherichia coli 3 0.8782
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A Q9Y233 PDE10_HUMAN Homo sapiens 3 0.8765
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A Q9Y233 PDE10_HUMAN Homo sapiens 3 0.8765
Pheromone-binding protein ASP1 Q9U9J6 Q9U9J6_APIME Apis mellifera 3 0.8753
Pheromone-binding protein ASP1 Q9U9J6 Q9U9J6_APIME Apis mellifera 3 0.8753
Abscisic acid receptor PYL1 Q8VZS8 PYL1_ARATH Arabidopsis thaliana 3 0.8750
Abscisic acid receptor PYL1 Q8VZS8 PYL1_ARATH Arabidopsis thaliana 3 0.8750
Acetolactate synthase, chloroplastic P17597 ILVB_ARATH Arabidopsis thaliana 3 0.8735
Acetolactate synthase, chloroplastic P17597 ILVB_ARATH Arabidopsis thaliana 3 0.8735
Heat shock protein HSP 90-alpha P07900 HS90A_HUMAN Homo sapiens 3 0.8733
Heat shock protein HSP 90-alpha P07900 HS90A_HUMAN Homo sapiens 3 0.8733
Toxoflavin degrading enzyme E3SET7 E3SET7_PAEPO Paenibacillus polymyxa 3 0.8679
Toxoflavin degrading enzyme E3SET7 E3SET7_PAEPO Paenibacillus polymyxa 3 0.8679
Prothrombin P00734 THRB_HUMAN Homo sapiens 3 0.8638
Prothrombin P00734 THRB_HUMAN Homo sapiens 3 0.8638
Succinate dehydrogenase flavoprotein subunit P0AC41 SDHA_ECOLI Escherichia coli 3 0.8636
Succinate dehydrogenase flavoprotein subunit P0AC41 SDHA_ECOLI Escherichia coli 3 0.8636
Tubulin alpha chain D0VWZ0 D0VWZ0_SHEEP Ovis aries 3 0.8611
Tubulin alpha chain D0VWZ0 D0VWZ0_SHEEP Ovis aries 3 0.8611
Heat shock protein HSP 90-alpha P07900 HS90A_HUMAN Homo sapiens 3 0.8584
Heat shock protein HSP 90-alpha P07900 HS90A_HUMAN Homo sapiens 3 0.8584
Tubulin alpha-1B chain P81947 TBA1B_BOVIN Bos taurus 3 0.8552
Tubulin alpha-1B chain P81947 TBA1B_BOVIN Bos taurus 3 0.8552
Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial Q33862 Q33862_ASCSU Ascaris suum 3 0.8545
Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial Q33862 Q33862_ASCSU Ascaris suum 3 0.8545
Lactoperoxidase P80025 PERL_BOVIN Bos taurus 3 0.8536
Lactoperoxidase P80025 PERL_BOVIN Bos taurus 3 0.8536
Carbonic anhydrase 2 P00918 CAH2_HUMAN Homo sapiens 3 0.8532
Carbonic anhydrase 2 P00918 CAH2_HUMAN Homo sapiens 3 0.8532
Endothiapepsin P11838 CARP_CRYPA Cryphonectria parasitica 3 0.8514
Endothiapepsin P11838 CARP_CRYPA Cryphonectria parasitica 3 0.8514
Heat shock protein HSP 90-alpha P07900 HS90A_HUMAN Homo sapiens 3 0.8510
Heat shock protein HSP 90-alpha P07900 HS90A_HUMAN Homo sapiens 3 0.8510
Succinate dehydrogenase flavoprotein subunit P0AC41 SDHA_ECOLI Escherichia coli 3 0.8504
Succinate dehydrogenase flavoprotein subunit P0AC41 SDHA_ECOLI Escherichia coli 3 0.8504
Mitogen-activated protein kinase 14 Q16539 MK14_HUMAN Homo sapiens 3 0.8487
Mitogen-activated protein kinase 14 Q16539 MK14_HUMAN Homo sapiens 3 0.8487
Prothrombin P00734 THRB_HUMAN Homo sapiens 3 0.8480
Prothrombin P00734 THRB_HUMAN Homo sapiens 3 0.8480
11-beta-hydroxysteroid dehydrogenase 1 P28845 DHI1_HUMAN Homo sapiens 3 0.8445
11-beta-hydroxysteroid dehydrogenase 1 P28845 DHI1_HUMAN Homo sapiens 3 0.8445
Fibroblast growth factor receptor 1 P11362 FGFR1_HUMAN Homo sapiens 3 0.8418
Fibroblast growth factor receptor 1 P11362 FGFR1_HUMAN Homo sapiens 3 0.8418
Alpha-1-acid glycoprotein 2 P19652 A1AG2_HUMAN Homo sapiens 3 0.8390
Alpha-1-acid glycoprotein 2 P19652 A1AG2_HUMAN Homo sapiens 3 0.8390
Cathepsin S P25774 CATS_HUMAN Homo sapiens 3 0.8380
Cathepsin S P25774 CATS_HUMAN Homo sapiens 3 0.8380
Carbonic anhydrase 2 P00918 CAH2_HUMAN Homo sapiens 3 0.8377
Carbonic anhydrase 2 P00918 CAH2_HUMAN Homo sapiens 3 0.8377
Serine/threonine-protein kinase pim-1 P11309 PIM1_HUMAN Homo sapiens 3 0.8359
Serine/threonine-protein kinase pim-1 P11309 PIM1_HUMAN Homo sapiens 3 0.8359
Proliferating cell nuclear antigen P12004 PCNA_HUMAN Homo sapiens 3 0.8304
Proliferating cell nuclear antigen P12004 PCNA_HUMAN Homo sapiens 3 0.8304
Renin P00797 RENI_HUMAN Homo sapiens 3 0.8294
Renin P00797 RENI_HUMAN Homo sapiens 3 0.8294
Carbonic anhydrase 2 P00918 CAH2_HUMAN Homo sapiens 3 0.8276
Carbonic anhydrase 2 P00918 CAH2_HUMAN Homo sapiens 3 0.8276
Glycylpeptide N-tetradecanoyltransferase Q4Q5S8 Q4Q5S8_LEIMA Leishmania major 3 0.8216
Glycylpeptide N-tetradecanoyltransferase Q4Q5S8 Q4Q5S8_LEIMA Leishmania major 3 0.8216
Serine/threonine-protein kinase 24 Q9Y6E0 STK24_HUMAN Homo sapiens 3 0.8163
Serine/threonine-protein kinase 24 Q9Y6E0 STK24_HUMAN Homo sapiens 3 0.8163
Acetolactate synthase catalytic subunit, mitochondrial P07342 ILVB_YEAST Saccharomyces cerevisiae 3 0.8151
Acetolactate synthase catalytic subunit, mitochondrial P07342 ILVB_YEAST Saccharomyces cerevisiae 3 0.8151
Thymidylate synthase P00469 TYSY_LACCA Lacticaseibacillus casei 3 0.8130
Thymidylate synthase P00469 TYSY_LACCA Lacticaseibacillus casei 3 0.8130
Glycogen synthase kinase-3 beta P49841 GSK3B_HUMAN Homo sapiens 3 0.8079
Glycogen synthase kinase-3 beta P49841 GSK3B_HUMAN Homo sapiens 3 0.8079
Homoserine dehydrogenase P31116 DHOM_YEAST Saccharomyces cerevisiae 3 0.8061
Homoserine dehydrogenase P31116 DHOM_YEAST Saccharomyces cerevisiae 3 0.8061
Carbonic anhydrase 2 P00918 CAH2_HUMAN Homo sapiens 3 0.8034
Carbonic anhydrase 2 P00918 CAH2_HUMAN Homo sapiens 3 0.8034
Histidine kinase 4 Q9C5U0 AHK4_ARATH Arabidopsis thaliana 3 0.8022
Histidine kinase 4 Q9C5U0 AHK4_ARATH Arabidopsis thaliana 3 0.8022
3',5'-cyclic-AMP phosphodiesterase 4D Q08499 PDE4D_HUMAN Homo sapiens 3 0.8006
3',5'-cyclic-AMP phosphodiesterase 4D Q08499 PDE4D_HUMAN Homo sapiens 3 0.8006
Beta-secretase 1 P56817 BACE1_HUMAN Homo sapiens 3 0.7999
Beta-secretase 1 P56817 BACE1_HUMAN Homo sapiens 3 0.7999
Gag-Pol polyprotein P12497 POL_HV1N5 Human immunodeficiency virus type 1 group M subtype B 3 0.7994
Gag-Pol polyprotein P12497 POL_HV1N5 Human immunodeficiency virus type 1 group M subtype B 3 0.7994
Thymidylate synthase P0A886 TYSY_ECO57 Escherichia coli O157:H7 3 0.7985
Thymidylate synthase P0A886 TYSY_ECO57 Escherichia coli O157:H7 3 0.7985
Gag-Pol polyprotein P03367 POL_HV1BR Human immunodeficiency virus type 1 group M subtype B 3 0.7971
Gag-Pol polyprotein P03367 POL_HV1BR Human immunodeficiency virus type 1 group M subtype B 3 0.7971
Activin receptor type-1 Q04771 ACVR1_HUMAN Homo sapiens 3 0.7967
Activin receptor type-1 Q04771 ACVR1_HUMAN Homo sapiens 3 0.7967
Prothrombin P00734 THRB_HUMAN Homo sapiens 3 0.7965
Prothrombin P00734 THRB_HUMAN Homo sapiens 3 0.7965
Acetylcholinesterase P22303 ACES_HUMAN Homo sapiens 3 0.7964
Acetylcholinesterase P22303 ACES_HUMAN Homo sapiens 3 0.7964
Major pollen allergen Bet v 1-A P15494 BEV1A_BETPN Betula pendula 3 0.7943
Major pollen allergen Bet v 1-A P15494 BEV1A_BETPN Betula pendula 3 0.7943
Odorant binding protein ASP1 Q8WRW5 Q8WRW5_APIME Apis mellifera 3 0.7932
Odorant binding protein ASP1 Q8WRW5 Q8WRW5_APIME Apis mellifera 3 0.7932
Poly [ADP-ribose] polymerase tankyrase-1 O95271 TNKS1_HUMAN Homo sapiens 3 0.7882
Poly [ADP-ribose] polymerase tankyrase-1 O95271 TNKS1_HUMAN Homo sapiens 3 0.7882
Pheromone-binding protein ASP1 Q9U9J6 Q9U9J6_APIME Apis mellifera 3 0.7833
Pheromone-binding protein ASP1 Q9U9J6 Q9U9J6_APIME Apis mellifera 3 0.7833
Gag-Pol polyprotein P12497 POL_HV1N5 Human immunodeficiency virus type 1 group M subtype B 3 0.7829
Gag-Pol polyprotein P12497 POL_HV1N5 Human immunodeficiency virus type 1 group M subtype B 3 0.7829
Basic phospholipase A2 VRV-PL-VIIIa P59071 PA2B8_DABRR Daboia russelii 3 0.7811
Basic phospholipase A2 VRV-PL-VIIIa P59071 PA2B8_DABRR Daboia russelii 3 0.7811
High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A O76083 PDE9A_HUMAN Homo sapiens 3 0.7797
High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A O76083 PDE9A_HUMAN Homo sapiens 3 0.7797
Cathepsin S P25774 CATS_HUMAN Homo sapiens 3 0.7790
Cathepsin S P25774 CATS_HUMAN Homo sapiens 3 0.7790
Serine/threonine-protein kinase Chk1 O14757 CHK1_HUMAN Homo sapiens 3 0.7775
Serine/threonine-protein kinase Chk1 O14757 CHK1_HUMAN Homo sapiens 3 0.7775
Phospholipase A2, major isoenzyme P00592 PA21B_PIG Sus scrofa 3 0.7761
Phospholipase A2, major isoenzyme P00592 PA21B_PIG Sus scrofa 3 0.7761
Peroxisome proliferator-activated receptor gamma P37231 PPARG_HUMAN Homo sapiens 3 0.7752
Peroxisome proliferator-activated receptor gamma P37231 PPARG_HUMAN Homo sapiens 3 0.7752
Gag-Pol polyprotein P12497 POL_HV1N5 Human immunodeficiency virus type 1 group M subtype B 3 0.7748
Gag-Pol polyprotein P12497 POL_HV1N5 Human immunodeficiency virus type 1 group M subtype B 3 0.7748
Putative S-adenosyl-L-methionine-dependent methyltransferase ML2640 Q9CCZ4 Y2640_MYCLE Mycobacterium leprae 3 0.7739
Putative S-adenosyl-L-methionine-dependent methyltransferase ML2640 Q9CCZ4 Y2640_MYCLE Mycobacterium leprae 3 0.7739
Tyrosine-protein kinase Lck P06239 LCK_HUMAN Homo sapiens 3 0.7698
Tyrosine-protein kinase Lck P06239 LCK_HUMAN Homo sapiens 3 0.7698
Ribosomal small subunit pseudouridine synthase A P0AA43 RSUA_ECOLI Escherichia coli 3 0.7693
Ribosomal small subunit pseudouridine synthase A P0AA43 RSUA_ECOLI Escherichia coli 3 0.7693
Heat shock protein HSP 90-alpha P07900 HS90A_HUMAN Homo sapiens 3 0.7693
Heat shock protein HSP 90-alpha P07900 HS90A_HUMAN Homo sapiens 3 0.7693
Gag-Pol polyprotein P05896 POL_SIVM1 Simian immunodeficiency virus 3 0.7691
Gag-Pol polyprotein P05896 POL_SIVM1 Simian immunodeficiency virus 3 0.7691
Carbonic anhydrase 2 P00918 CAH2_HUMAN Homo sapiens 3 0.7690
Carbonic anhydrase 2 P00918 CAH2_HUMAN Homo sapiens 3 0.7690
Nodulin-13 P93330 NOD13_MEDTR Medicago truncatula 3 0.7677
Nodulin-13 P93330 NOD13_MEDTR Medicago truncatula 3 0.7677
Mycocyclosin synthase P9WPP7 CP121_MYCTU Mycobacterium tuberculosis 3 0.7661
Mycocyclosin synthase P9WPP7 CP121_MYCTU Mycobacterium tuberculosis 3 0.7661
Lactotransferrin P24627 TRFL_BOVIN Bos taurus 2 0.7650
Lactotransferrin P24627 TRFL_BOVIN Bos taurus 2 0.7650
Gag-Pol polyprotein P12497 POL_HV1N5 Human immunodeficiency virus type 1 group M subtype B 3 0.7644
Gag-Pol polyprotein P12497 POL_HV1N5 Human immunodeficiency virus type 1 group M subtype B 3 0.7644
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform P48736 PK3CG_HUMAN Homo sapiens 3 0.7629
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform P48736 PK3CG_HUMAN Homo sapiens 3 0.7629
Beta-secretase 1 P56817 BACE1_HUMAN Homo sapiens 2 0.7627
Beta-secretase 1 P56817 BACE1_HUMAN Homo sapiens 2 0.7627
WxcM-like protein Q12KT8 Q12KT8_SHEDO Shewanella denitrificans 3 0.7621
WxcM-like protein Q12KT8 Q12KT8_SHEDO Shewanella denitrificans 3 0.7621
Beta-secretase 1 P56817 BACE1_HUMAN Homo sapiens 2 0.7605
Beta-secretase 1 P56817 BACE1_HUMAN Homo sapiens 2 0.7605
Serine/threonine-protein kinase SKY1 Q03656 SKY1_YEAST Saccharomyces cerevisiae 3 0.7597
Serine/threonine-protein kinase SKY1 Q03656 SKY1_YEAST Saccharomyces cerevisiae 3 0.7597
Mycocyclosin synthase P9WPP7 CP121_MYCTU Mycobacterium tuberculosis 3 0.7593
Mycocyclosin synthase P9WPP7 CP121_MYCTU Mycobacterium tuberculosis 3 0.7593
Basic phospholipase A2 VRV-PL-VIIIa P59071 PA2B8_DABRR Daboia russelii 2 0.7590
Basic phospholipase A2 VRV-PL-VIIIa P59071 PA2B8_DABRR Daboia russelii 2 0.7590
Beta-secretase 1 P56817 BACE1_HUMAN Homo sapiens 2 0.7576
Beta-secretase 1 P56817 BACE1_HUMAN Homo sapiens 2 0.7576
Type IV / VI secretion system DotU domain-containing protein Q9KN50 Q9KN50_VIBCH Vibrio cholerae serotype O1 3 0.7573
Type IV / VI secretion system DotU domain-containing protein Q9KN50 Q9KN50_VIBCH Vibrio cholerae serotype O1 3 0.7573
Glutamate receptor 2 P19491 GRIA2_RAT Rattus norvegicus 3 0.7565
Glutamate receptor 2 P19491 GRIA2_RAT Rattus norvegicus 3 0.7565
Carbonic anhydrase 2 P00918 CAH2_HUMAN Homo sapiens 3 0.7557
Epidermal growth factor receptor P00533 EGFR_HUMAN Homo sapiens 3 0.7557
Carbonic anhydrase 2 P00918 CAH2_HUMAN Homo sapiens 3 0.7557
Epidermal growth factor receptor P00533 EGFR_HUMAN Homo sapiens 3 0.7557
Heat shock protein HSP 90-alpha P07900 HS90A_HUMAN Homo sapiens 3 0.7544
Heat shock protein HSP 90-alpha P07900 HS90A_HUMAN Homo sapiens 3 0.7544
Riboflavin biosynthesis protein Q9WZW1 Q9WZW1_THEMA Thermotoga maritima 3 0.7527
Riboflavin biosynthesis protein Q9WZW1 Q9WZW1_THEMA Thermotoga maritima 3 0.7527
Beta-secretase 1 P56817 BACE1_HUMAN Homo sapiens 2 0.7525
Beta-secretase 1 P56817 BACE1_HUMAN Homo sapiens 2 0.7525
Gag-Pol polyprotein P12497 POL_HV1N5 Human immunodeficiency virus type 1 group M subtype B 3 0.7523
Gag-Pol polyprotein P12497 POL_HV1N5 Human immunodeficiency virus type 1 group M subtype B 3 0.7523
Nitric oxide synthase, inducible P29477 NOS2_MOUSE Mus musculus 3 0.7504
Macrophage metalloelastase P39900 MMP12_HUMAN Homo sapiens 3 0.7504
Nitric oxide synthase, inducible P29477 NOS2_MOUSE Mus musculus 3 0.7504
Macrophage metalloelastase P39900 MMP12_HUMAN Homo sapiens 3 0.7504
Thymidylate synthase P00469 TYSY_LACCA Lacticaseibacillus casei 2 0.7503
Thymidylate synthase P00469 TYSY_LACCA Lacticaseibacillus casei 2 0.7503
Putative cytochrome P450 Q70AS3 Q70AS3_STRPE Streptomyces peucetius 3 0.7495
Putative cytochrome P450 Q70AS3 Q70AS3_STRPE Streptomyces peucetius 3 0.7495
Thiamine-phosphate synthase P39594 THIE_BACSU Bacillus subtilis 3 0.7478
Thiamine-phosphate synthase P39594 THIE_BACSU Bacillus subtilis 3 0.7478
17-beta-hydroxysteroid dehydrogenase type 1 P14061 DHB1_HUMAN Homo sapiens 2 0.7476
17-beta-hydroxysteroid dehydrogenase type 1 P14061 DHB1_HUMAN Homo sapiens 2 0.7476
Nitric oxide synthase, inducible P29477 NOS2_MOUSE Mus musculus 3 0.7473
Nitric oxide synthase, inducible P29477 NOS2_MOUSE Mus musculus 3 0.7473
Cholinesterase P06276 CHLE_HUMAN Homo sapiens 2 0.7467
Cholinesterase P06276 CHLE_HUMAN Homo sapiens 2 0.7467
Aminoglycoside 3'-phosphotransferase AphA1-IAB B0VD92 B0VD92_ACIBY Acinetobacter baumannii 3 0.7458
Aminoglycoside 3'-phosphotransferase AphA1-IAB B0VD92 B0VD92_ACIBY Acinetobacter baumannii 3 0.7458
Soluble acetylcholine receptor Q8WSF8 Q8WSF8_APLCA Aplysia californica 2 0.7429
Soluble acetylcholine receptor Q8WSF8 Q8WSF8_APLCA Aplysia californica 2 0.7429
Albumin P02768 ALBU_HUMAN Homo sapiens 3 0.7425
FMN-dependent NAD(P)H:quinone oxidoreductase 1 Q9I5F3 AZOR1_PSEAE Pseudomonas aeruginosa 3 0.7425
Albumin P02768 ALBU_HUMAN Homo sapiens 3 0.7425
FMN-dependent NAD(P)H:quinone oxidoreductase 1 Q9I5F3 AZOR1_PSEAE Pseudomonas aeruginosa 3 0.7425
Metallo-beta-lactamase type 2 P52699 BLAB_SERMA Serratia marcescens 3 0.7424
Metallo-beta-lactamase type 2 P52699 BLAB_SERMA Serratia marcescens 3 0.7424
Mitogen-activated protein kinase 14 Q16539 MK14_HUMAN Homo sapiens 3 0.7421
Mitogen-activated protein kinase 14 Q16539 MK14_HUMAN Homo sapiens 3 0.7421
4-hydroxyphenylacetate 3-monooxygenase Q8YHT7 Q8YHT7_BRUME Brucella melitensis biotype 1 2 0.7418
4-hydroxyphenylacetate 3-monooxygenase Q8YHT7 Q8YHT7_BRUME Brucella melitensis biotype 1 2 0.7418
Prostaglandin G/H synthase 1 P05979 PGH1_SHEEP Ovis aries 3 0.7417
Prostaglandin G/H synthase 1 P05979 PGH1_SHEEP Ovis aries 3 0.7417
Serine/threonine-protein kinase pim-1 P11309 PIM1_HUMAN Homo sapiens 2 0.7414
Serine/threonine-protein kinase pim-1 P11309 PIM1_HUMAN Homo sapiens 2 0.7414
Cytosolic purine 5'-nucleotidase P49902 5NTC_HUMAN Homo sapiens 2 0.7410
Cytosolic purine 5'-nucleotidase P49902 5NTC_HUMAN Homo sapiens 2 0.7410
Lethal(3)malignant brain tumor-like protein 1 Q9Y468 LMBL1_HUMAN Homo sapiens 3 0.7409
Lethal(3)malignant brain tumor-like protein 1 Q9Y468 LMBL1_HUMAN Homo sapiens 3 0.7409
Mitochondrial poly(A) polymerase F1NBW0 F1NBW0_CHICK Gallus gallus 2 0.7406
Mitochondrial poly(A) polymerase F1NBW0 F1NBW0_CHICK Gallus gallus 2 0.7406
Pancreatic alpha-amylase P04746 AMYP_HUMAN Homo sapiens 2 0.7403
Pancreatic alpha-amylase P04746 AMYP_HUMAN Homo sapiens 2 0.7403
Histidine kinase 4 Q9C5U0 AHK4_ARATH Arabidopsis thaliana 3 0.7395
Histidine kinase 4 Q9C5U0 AHK4_ARATH Arabidopsis thaliana 3 0.7395
Genome polyprotein O92972 POLG_HCVJ4 Hepatitis C virus genotype 1b 3 0.7392
Genome polyprotein O92972 POLG_HCVJ4 Hepatitis C virus genotype 1b 3 0.7392
Matrix metalloproteinase-20 O60882 MMP20_HUMAN Homo sapiens 3 0.7389
Matrix metalloproteinase-20 O60882 MMP20_HUMAN Homo sapiens 3 0.7389
HLA class I histocompatibility antigen, B alpha chain P01889 HLAB_HUMAN Homo sapiens 3 0.7388
HLA class I histocompatibility antigen, B alpha chain P01889 HLAB_HUMAN Homo sapiens 3 0.7388
Peptidyl-prolyl cis-trans isomerase FKBP1A P62942 FKB1A_HUMAN Homo sapiens 2 0.7372
Peptidyl-prolyl cis-trans isomerase FKBP1A P62942 FKB1A_HUMAN Homo sapiens 2 0.7372
Acetylcholinesterase P04058 ACES_TETCF Tetronarce californica 3 0.7365
Acetylcholinesterase P04058 ACES_TETCF Tetronarce californica 3 0.7365
Thymidylate synthase P00469 TYSY_LACCA Lacticaseibacillus casei 2 0.7353
Thymidylate synthase P00469 TYSY_LACCA Lacticaseibacillus casei 2 0.7353
L-lactate dehydrogenase Q5SJA1 LDH_THET8 Thermus thermophilus 3 0.7346
L-lactate dehydrogenase Q5SJA1 LDH_THET8 Thermus thermophilus 3 0.7346
Flavin-dependent monooxygenase Q93L51 TETX_BACT4 Bacteroides thetaiotaomicron 2 0.7344
Flavin-dependent monooxygenase Q93L51 TETX_BACT4 Bacteroides thetaiotaomicron 2 0.7344
Polymerase acidic protein C3W5S0 C3W5S0_I09A0 Influenza A virus 2 0.7336
Polymerase acidic protein C3W5S0 C3W5S0_I09A0 Influenza A virus 2 0.7336
Gag-Pol polyprotein P04584 POL_HV2RO Human immunodeficiency virus type 2 subtype A 3 0.7328
Gag-Pol polyprotein P04584 POL_HV2RO Human immunodeficiency virus type 2 subtype A 3 0.7328
Adenylate cyclase type 5 P30803 ADCY5_CANLF Canis lupus familiaris 3 0.7326
Adenylate cyclase type 5 P30803 ADCY5_CANLF Canis lupus familiaris 3 0.7326
High affinity 3',5'-cyclic-AMP phosphodiesterase 7A Q13946 PDE7A_HUMAN Homo sapiens 3 0.7324
Uncharacterized protein Q3F0V8 Q3F0V8_BACTI Bacillus thuringiensis serovar israelensis ATCC 35646 3 0.7324
High affinity 3',5'-cyclic-AMP phosphodiesterase 7A Q13946 PDE7A_HUMAN Homo sapiens 3 0.7324
Uncharacterized protein Q3F0V8 Q3F0V8_BACTI Bacillus thuringiensis serovar israelensis ATCC 35646 3 0.7324
histone deacetylase A5H660 A5H660_SCHMA Schistosoma mansoni 3 0.7312
histone deacetylase A5H660 A5H660_SCHMA Schistosoma mansoni 3 0.7312
Basic phospholipase A2 VRV-PL-VIIIa P59071 PA2B8_DABRR Daboia russelii 2 0.7307
Basic phospholipase A2 VRV-PL-VIIIa P59071 PA2B8_DABRR Daboia russelii 2 0.7307
Nitric oxide synthase, inducible P29477 NOS2_MOUSE Mus musculus 3 0.7305
Nitric oxide synthase, inducible P29477 NOS2_MOUSE Mus musculus 3 0.7305
Lactotransferrin P24627 TRFL_BOVIN Bos taurus 3 0.7297
Lactotransferrin P24627 TRFL_BOVIN Bos taurus 3 0.7297
Protein S100-A13 Q99584 S10AD_HUMAN Homo sapiens 2 0.7288
Protein S100-A13 Q99584 S10AD_HUMAN Homo sapiens 2 0.7288
NAD(P)H dehydrogenase [quinone] 1 P15559 NQO1_HUMAN Homo sapiens 3 0.7280
NAD(P)H dehydrogenase [quinone] 1 P15559 NQO1_HUMAN Homo sapiens 3 0.7280
Pentalenic acid synthase Q825I8 CYP28_STRAW Streptomyces avermitilis 2 0.7278
Pentalenic acid synthase Q825I8 CYP28_STRAW Streptomyces avermitilis 2 0.7278
L-lactate dehydrogenase A chain P04642 LDHA_RAT Rattus norvegicus 3 0.7274
L-lactate dehydrogenase A chain P04642 LDHA_RAT Rattus norvegicus 3 0.7274
Glycogen synthase kinase-3 beta P49841 GSK3B_HUMAN Homo sapiens 3 0.7272
Glycogen synthase kinase-3 beta P49841 GSK3B_HUMAN Homo sapiens 3 0.7272
Mitogen-activated protein kinase 14 Q16539 MK14_HUMAN Homo sapiens 4 0.7266
Mitogen-activated protein kinase 14 Q16539 MK14_HUMAN Homo sapiens 4 0.7266
Urokinase-type plasminogen activator P00749 UROK_HUMAN Homo sapiens 2 0.7255
Aldo-keto reductase family 1 member B1 P15121 ALDR_HUMAN Homo sapiens 3 0.7255
Urokinase-type plasminogen activator P00749 UROK_HUMAN Homo sapiens 2 0.7255
Aldo-keto reductase family 1 member B1 P15121 ALDR_HUMAN Homo sapiens 3 0.7255
Protein ppBat Q8A8A4 Q8A8A4_BACTN Bacteroides thetaiotaomicron VPI-5482 3 0.7245
Protein ppBat Q8A8A4 Q8A8A4_BACTN Bacteroides thetaiotaomicron VPI-5482 3 0.7245
Beta-galactoside-specific lectin 4 Q6ITZ3 ML4_VISAL Viscum album 2 0.7234
Beta-galactoside-specific lectin 4 Q6ITZ3 ML4_VISAL Viscum album 2 0.7234
Casein kinase I isoform gamma-3 Q9Y6M4 KC1G3_HUMAN Homo sapiens 3 0.7230
Casein kinase I isoform gamma-3 Q9Y6M4 KC1G3_HUMAN Homo sapiens 3 0.7230
Aklavinone 12-hydroxylase RdmE Q54530 DNRF_STREF Streptomyces purpurascens 4 0.7227
Aklavinone 12-hydroxylase RdmE Q54530 DNRF_STREF Streptomyces purpurascens 4 0.7227
Prothrombin P00734 THRB_HUMAN Homo sapiens 3 0.7223
Prothrombin P00734 THRB_HUMAN Homo sapiens 3 0.7223
Xylose isomerase P24300 XYLA_STRRU Streptomyces rubiginosus 3 0.7220
Xylose isomerase P24300 XYLA_STRRU Streptomyces rubiginosus 3 0.7220
Beta-lactamase Q9L5C8 Q9L5C8_ECOLX Escherichia coli 3 0.7215
Beta-lactamase Q9L5C8 Q9L5C8_ECOLX Escherichia coli 3 0.7215
Tannase B3Y018 B3Y018_LACPN Lactiplantibacillus plantarum 3 0.7213
Tannase B3Y018 B3Y018_LACPN Lactiplantibacillus plantarum 3 0.7213
Pyridoxal kinase P82197 PDXK_SHEEP Ovis aries 3 0.7205
Pyridoxal kinase P82197 PDXK_SHEEP Ovis aries 3 0.7205
Nitric oxide synthase, inducible P29477 NOS2_MOUSE Mus musculus 3 0.7200
Nitric oxide synthase, inducible P29477 NOS2_MOUSE Mus musculus 3 0.7200
Prothrombin P00734 THRB_HUMAN Homo sapiens 3 0.7196
Prothrombin P00734 THRB_HUMAN Homo sapiens 3 0.7196
Eukaryotic translation initiation factor 4E type 3 Q9DBB5 IF4E3_MOUSE Mus musculus 3 0.7195
Eukaryotic translation initiation factor 4E type 3 Q9DBB5 IF4E3_MOUSE Mus musculus 3 0.7195
FMN-dependent NAD(P)H:quinone oxidoreductase 1 Q9I5F3 AZOR1_PSEAE Pseudomonas aeruginosa 2 0.7194
FMN-dependent NAD(P)H:quinone oxidoreductase 1 Q9I5F3 AZOR1_PSEAE Pseudomonas aeruginosa 2 0.7194
Serine/threonine-protein kinase PLK1 P53350 PLK1_HUMAN Homo sapiens 3 0.7189
Serine/threonine-protein kinase PLK1 P53350 PLK1_HUMAN Homo sapiens 3 0.7189
Histamine N-methyltransferase P50135 HNMT_HUMAN Homo sapiens 2 0.7185
Histamine N-methyltransferase P50135 HNMT_HUMAN Homo sapiens 2 0.7185
Gentisate 1,2-dioxygenase Q67FT0 Q67FT0_PSESE Pseudaminobacter salicylatoxidans 2 0.7172
Gentisate 1,2-dioxygenase Q67FT0 Q67FT0_PSESE Pseudaminobacter salicylatoxidans 2 0.7172
Lactotransferrin P24627 TRFL_BOVIN Bos taurus 2 0.7170
Lactotransferrin P24627 TRFL_BOVIN Bos taurus 2 0.7170
Aldo-keto reductase family 1 member C3 P42330 AK1C3_HUMAN Homo sapiens 2 0.7168
Hypoxanthine phosphoribosyltransferase Q4DRC4 Q4DRC4_TRYCC Trypanosoma cruzi 2 0.7168
Hypoxanthine phosphoribosyltransferase Q4DRC4 Q4DRC4_TRYCC Trypanosoma cruzi 2 0.7168
Aldo-keto reductase family 1 member C3 P42330 AK1C3_HUMAN Homo sapiens 2 0.7168
Gag-Pol polyprotein P03367 POL_HV1BR Human immunodeficiency virus type 1 group M subtype B 3 0.7162
Gag-Pol polyprotein P03367 POL_HV1BR Human immunodeficiency virus type 1 group M subtype B 3 0.7162
Uracil phosphoribosyltransferase Q26998 UPP_TOXGO Toxoplasma gondii 2 0.7162
Uracil phosphoribosyltransferase Q26998 UPP_TOXGO Toxoplasma gondii 2 0.7162
Nitric oxide synthase oxygenase O34453 NOSO_BACSU Bacillus subtilis 3 0.7158
Nitric oxide synthase oxygenase O34453 NOSO_BACSU Bacillus subtilis 3 0.7158
Capsid protein Q9WBP8 Q9WBP8_9VIRU Adeno-associated virus - 1 3 0.7154
Capsid protein Q9WBP8 Q9WBP8_9VIRU Adeno-associated virus - 1 3 0.7154
Tyrosine-protein kinase JAK2 O60674 JAK2_HUMAN Homo sapiens 3 0.7150
Tyrosine-protein kinase JAK2 O60674 JAK2_HUMAN Homo sapiens 3 0.7150
Macrophage colony-stimulating factor 1 receptor P07333 CSF1R_HUMAN Homo sapiens 3 0.7122
Macrophage colony-stimulating factor 1 receptor P07333 CSF1R_HUMAN Homo sapiens 3 0.7122
Gag-Pol polyprotein P12497 POL_HV1N5 Human immunodeficiency virus type 1 group M subtype B 2 0.7118
Gag-Pol polyprotein P12497 POL_HV1N5 Human immunodeficiency virus type 1 group M subtype B 2 0.7118
CCA-adding enzyme O28126 CCA_ARCFU Archaeoglobus fulgidus 2 0.7113
Cystathionine gamma-synthase P56069 METB_HELPY Helicobacter pylori 3 0.7113
Beta-lactamase P00811 AMPC_ECOLI Escherichia coli 3 0.7113
Beta-lactamase P00811 AMPC_ECOLI Escherichia coli 3 0.7113
cAMP-dependent protein kinase type I-alpha regulatory subunit P00514 KAP0_BOVIN Bos taurus 2 0.7113
Cystathionine gamma-synthase P56069 METB_HELPY Helicobacter pylori 3 0.7113
cAMP-dependent protein kinase type I-alpha regulatory subunit P00514 KAP0_BOVIN Bos taurus 2 0.7113
CCA-adding enzyme O28126 CCA_ARCFU Archaeoglobus fulgidus 2 0.7113
Pentaerythritol tetranitrate reductase P71278 P71278_ENTCL Enterobacter cloacae 2 0.7110
Pentaerythritol tetranitrate reductase P71278 P71278_ENTCL Enterobacter cloacae 2 0.7110
Heat shock protein 75 kDa, mitochondrial Q12931 TRAP1_HUMAN Homo sapiens 3 0.7108
Heat shock protein 75 kDa, mitochondrial Q12931 TRAP1_HUMAN Homo sapiens 3 0.7108
Carbonic anhydrase 2 P00918 CAH2_HUMAN Homo sapiens 2 0.7103
Carbonic anhydrase 2 P00918 CAH2_HUMAN Homo sapiens 2 0.7103
Uracil phosphoribosyltransferase Q26998 UPP_TOXGO Toxoplasma gondii 2 0.7101
Uracil phosphoribosyltransferase Q26998 UPP_TOXGO Toxoplasma gondii 2 0.7101
Cytochrome P450 130 P9WPN5 CP130_MYCTU Mycobacterium tuberculosis 2 0.7096
Cytochrome P450 130 P9WPN5 CP130_MYCTU Mycobacterium tuberculosis 2 0.7096
cGMP-dependent protein kinase 1 Q13976 KGP1_HUMAN Homo sapiens 2 0.7091
Nitric oxide synthase, inducible P29477 NOS2_MOUSE Mus musculus 3 0.7091
Nitric oxide synthase, inducible P29477 NOS2_MOUSE Mus musculus 3 0.7091
cGMP-dependent protein kinase 1 Q13976 KGP1_HUMAN Homo sapiens 2 0.7091
Calmodulin-domain protein kinase 1, putative A3FQ16 A3FQ16_CRYPI Cryptosporidium parvum 3 0.7089
Nitric oxide synthase, inducible P29477 NOS2_MOUSE Mus musculus 3 0.7089
Calmodulin-domain protein kinase 1, putative A3FQ16 A3FQ16_CRYPI Cryptosporidium parvum 3 0.7089
Nitric oxide synthase, inducible P29477 NOS2_MOUSE Mus musculus 3 0.7089
DNA topoisomerase 4 subunit B H7C794 PARE_ENTFA Enterococcus faecalis 2 0.7088
DNA topoisomerase 4 subunit B H7C794 PARE_ENTFA Enterococcus faecalis 2 0.7088
DNA-directed DNA polymerase Q38087 DPOL_BPR69 Escherichia phage RB69 2 0.7087
DNA-directed DNA polymerase Q38087 DPOL_BPR69 Escherichia phage RB69 2 0.7087
Cyclic nucleotide-gated potassium channel mll3241 Q98GN8 CNGK1_RHILO Mesorhizobium japonicum) 2 0.7083
Cyclic nucleotide-gated potassium channel mll3241 Q98GN8 CNGK1_RHILO Mesorhizobium japonicum) 2 0.7083
Metallo-beta-lactamase type 2 P25910 BLAB_BACFG Bacteroides fragilis 3 0.7075
Metallo-beta-lactamase type 2 P25910 BLAB_BACFG Bacteroides fragilis 3 0.7075
Tyrosine-protein kinase Lck P06239 LCK_HUMAN Homo sapiens 3 0.7069
Tyrosine-protein kinase Lck P06239 LCK_HUMAN Homo sapiens 3 0.7069
Beta-secretase 1 P56817 BACE1_HUMAN Homo sapiens 4 0.7065
Beta-secretase 1 P56817 BACE1_HUMAN Homo sapiens 4 0.7065
HTH-type transcriptional regulator QacR P0A0N4 QACR_STAAU Staphylococcus aureus 2 0.7056
HTH-type transcriptional regulator QacR P0A0N4 QACR_STAAU Staphylococcus aureus 2 0.7056
Muscarinic acetylcholine receptor M3 P08483 ACM3_RAT Rattus norvegicus 4 0.7050
Muscarinic acetylcholine receptor M3 P08483 ACM3_RAT Rattus norvegicus 4 0.7050
Angiotensin-converting enzyme 2 Q9BYF1 ACE2_HUMAN Homo sapiens 2 0.7049
Angiotensin-converting enzyme 2 Q9BYF1 ACE2_HUMAN Homo sapiens 2 0.7049
Aldo-keto reductase family 1 member C3 P42330 AK1C3_HUMAN Homo sapiens 2 0.7048
Aldo-keto reductase family 1 member C3 P42330 AK1C3_HUMAN Homo sapiens 2 0.7048
Tyrosine-protein kinase HCK P08631 HCK_HUMAN Homo sapiens 3 0.7041
Tyrosine-protein kinase HCK P08631 HCK_HUMAN Homo sapiens 3 0.7041
L-lactate dehydrogenase A chain P13491 LDHA_RABIT Oryctolagus cuniculus 2 0.7040
L-lactate dehydrogenase A chain P13491 LDHA_RABIT Oryctolagus cuniculus 2 0.7040
Adenylate cyclase type 5 P30803 ADCY5_CANLF Canis lupus familiaris 3 0.7035
Adenylate cyclase type 5 P30803 ADCY5_CANLF Canis lupus familiaris 3 0.7035
Muscarinic acetylcholine receptor M3 P08483 ACM3_RAT Rattus norvegicus 4 0.7034
Muscarinic acetylcholine receptor M3 P08483 ACM3_RAT Rattus norvegicus 4 0.7034
Mycocyclosin synthase P9WPP7 CP121_MYCTU Mycobacterium tuberculosis 2 0.7025
Purine nucleoside phosphorylase DeoD-type P0ABP9 DEOD_ECO57 Escherichia coli O157:H7 3 0.7025
Cis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase Q46381 BPHB_COMTE Comamonas testosteroni 3 0.7025
Purine nucleoside phosphorylase DeoD-type P0ABP9 DEOD_ECO57 Escherichia coli O157:H7 3 0.7025
Mycocyclosin synthase P9WPP7 CP121_MYCTU Mycobacterium tuberculosis 2 0.7025
Cis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase Q46381 BPHB_COMTE Comamonas testosteroni 3 0.7025
Lethal factor P15917 LEF_BACAN Bacillus anthracis 3 0.7015
Lethal factor P15917 LEF_BACAN Bacillus anthracis 3 0.7015
Glucose-1-phosphate thymidylyltransferase Q9HU22 Q9HU22_PSEAE Pseudomonas aeruginosa 3 0.7009
Glucose-1-phosphate thymidylyltransferase Q9HU22 Q9HU22_PSEAE Pseudomonas aeruginosa 3 0.7009
Pheromone-binding protein ASP1 Q9U9J6 Q9U9J6_APIME Apis mellifera 3 0.7006
Pheromone-binding protein ASP1 Q9U9J6 Q9U9J6_APIME Apis mellifera 3 0.7006
Tubulin alpha-1B chain P81947 TBA1B_BOVIN Bos taurus 3 0.7001
Tubulin alpha-1B chain P81947 TBA1B_BOVIN Bos taurus 3 0.7001
Cyclin-dependent kinase 2 P24941 CDK2_HUMAN Homo sapiens 3 0.7001
Cyclin-dependent kinase 2 P24941 CDK2_HUMAN Homo sapiens 3 0.7001

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