Cleistenechlorohydrin A - Compound Card

Cleistenechlorohydrin A

Select a section from the left sidebar

Cleistenechlorohydrin A

Structure
Zoomed Structure
  • Family: Annonaceae
  • Kingdom: Plantae
  • Class: Cyclohexene Derivative
    • Subclass: Polyoxygenated Cyclohexene Derivative
Canonical Smiles CC(=O)O[C@@H]1C=C[C@H]([C@]([C@H]1O)(O)COC(=O)c1ccccc1)Cl
InChI InChI=1S/C16H17ClO6/c1-10(18)23-12-7-8-13(17)16(21,14(12)19)9-22-15(20)11-5-3-2-4-6-11/h2-8,12-14,19,21H,9H2,1H3/t12-,13-,14+,16-/m1/s1
InChIKey YEEMXVYHDPMVQJ-HGTKMLMNSA-N
Formula C16H17ClO6
HBA 6
HBD 2
MW 340.76
Rotatable Bonds 4
TPSA 93.06
LogP 1.04
Number Rings 2
Number Aromatic Rings 1
Heavy Atom Count 23
Formal Charge 0
Fraction CSP3 0.38
Exact Mass 340.07
Number of Lipinski Rule Violations 0
# Species Family Kingdom NCBI Taxonomy ID
1 Cleistochlamys kirkii Annonaceae Plantae 1237197

Showing of synonyms

  • Nyandoro SS, Munissi JJ, et al. (2017). Polyoxygenated cyclohexenes and other constituents of Cleistochlamys kirkii leaves. Journal of Natural Products,2017,80(1),114-125. [View] [PubMed]

No compound-protein relationship available.

Structure

SMILES: c1ccccc1C(=O)OCC2CC=CCC2

Level: 1

Mol. Weight: 216.28 g/mol

Structure

SMILES: C1=CCCCC1

Level: 0

Mol. Weight: 82.15 g/mol

Structure

SMILES: c1ccccc1

Level: 0

Mol. Weight: 78.11 g/mol

Anti-plasmodial
Cytotoxic

Absorption

Caco-2 (logPapp)
-5.09
Human Oral Bioavailability 20%
Bioavailable
Human Intestinal Absorption
Absorbed
Madin-Darby Canine Kidney
-4.66
Human Oral Bioavailability 50%
Non-Bioavailable
P-Glycoprotein Inhibitor
Non-Inhibitor
P-Glycoprotein Substrate
Non-Substrate
Skin Permeability
-2.49

Distribution

Blood-Brain Barrier (CNS)
-
Blood-Brain Barrier
Penetrable
Fraction Unbound (Human)
0.61
Plasma Protein Binding
49.48
Steady State Volume of Distribution
-

Metabolism

Breast Cancer Resistance Protein
Non-Inhibitor
CYP 1A2 Inhibitor
Inhibitor
CYP 1A2 Substrate
Non-Substrate
CYP 2C19 Inhibitor
Non-Inhibitor
CYP 2C19 Substrate
Non-Substrate
CYP 2C9 Inhibitor
Non-Inhibitor
CYP 2C9 Substrate
Non-Substrate
CYP 2D6 Inhibitor
Non-Inhibitor
CYP 2D6 Substrate
Non-Substrate
CYP 3A4 Inhibitor
Non-Inhibitor
CYP 3A4 Substrate
Non-Substrate
OATP1B1
Non-Inhibitor
OATP1B3
Non-Inhibitor

Excretion

Clearance
4.24
Organic Cation Transporter 2
Non-Inhibitor
Half-Life of Drug
-

Toxicity

AMES Mutagenesis
Toxic
Avian
Safe
Bee
Safe
Bioconcentration Factor
-0.05
Biodegradation
Toxic
Carcinogenesis
Safe
Crustacean
Safe
Liver Injury I (DILI)
Safe
Eye Corrosion
Safe
Eye Irritation
Safe
Maximum Tolerated Dose
1.17
Liver Injury II
Toxic
hERG Blockers
Safe
Daphnia Maga
5.67
Micronucleos
Toxic
NR-AhR
Safe
NR-AR
Safe
NR-AR-LBD
Safe
NR-Aromatase
Safe
NR-ER
Safe
NR-ER-LBD
Safe
NR-GR
Safe
NR-PPAR-gamma
Safe
NR-TR
Safe
T. Pyriformis
-0.09
Rat (Acute)
2.66
Rat (Chronic Oral)
2.69
Fathead Minnow
4.05
Respiratory Disease
Safe
Skin Sensitisation
Safe
SR-ARE
Safe
SR-ATAD5
Safe
SR-HSE
Safe
SR-MMP
Safe
SR-p53
Safe

General Properties

Boiling Point
350.36
Hydration Free Energy
-11.66
Log(D) at pH=7.4
1.44
Log(P)
1.99
Log S
-2.66
Log(Vapor Pressure)
-7.69
Melting Point
136.56
pKa Acid
7.62
pKa Basic
1.56
Protein Name UniProt ID Entry Name Species #Pharmacophore Points Probability (0.7 ≤ Tversky Score ≤ 1.0)
Tetracycline repressor protein class D P0ACT4 TETR4_ECOLX Escherichia coli 3 0.9572
Tetracycline repressor protein class D P0ACT4 TETR4_ECOLX Escherichia coli 3 0.9572
Lactoperoxidase P80025 PERL_BOVIN Bos taurus 3 0.9545
Lactoperoxidase P80025 PERL_BOVIN Bos taurus 3 0.9545
Peptidyl-prolyl cis-trans isomerase FKBP1A P62942 FKB1A_HUMAN Homo sapiens 3 0.9422
Peptidyl-prolyl cis-trans isomerase FKBP1A P62942 FKB1A_HUMAN Homo sapiens 3 0.9422
Endothiapepsin P11838 CARP_CRYPA Cryphonectria parasitica 3 0.9211
Endothiapepsin P11838 CARP_CRYPA Cryphonectria parasitica 3 0.9211
Prothrombin P00734 THRB_HUMAN Homo sapiens 3 0.9167
Prothrombin P00734 THRB_HUMAN Homo sapiens 3 0.9167
Neocarzinostatin P0A3R9 NCZS_STRCZ Streptomyces carzinostaticus 3 0.8562
Neocarzinostatin P0A3R9 NCZS_STRCZ Streptomyces carzinostaticus 3 0.8562
Type IV / VI secretion system DotU domain-containing protein Q9KN50 Q9KN50_VIBCH Vibrio cholerae serotype O1 3 0.8498
Type IV / VI secretion system DotU domain-containing protein Q9KN50 Q9KN50_VIBCH Vibrio cholerae serotype O1 3 0.8498
Flavin-dependent monooxygenase Q93L51 TETX_BACT4 Bacteroides thetaiotaomicron 3 0.8476
Flavin-dependent monooxygenase Q93L51 TETX_BACT4 Bacteroides thetaiotaomicron 3 0.8476
Endothiapepsin P11838 CARP_CRYPA Cryphonectria parasitica 3 0.8173
Endothiapepsin P11838 CARP_CRYPA Cryphonectria parasitica 3 0.8173
Diphtheria toxin P00588 DTX_CORBE Corynephage beta 3 0.7967
Diphtheria toxin P00588 DTX_CORBE Corynephage beta 3 0.7967
Gag-Pol polyprotein P05896 POL_SIVM1 Simian immunodeficiency virus 4 0.7956
Gag-Pol polyprotein P05896 POL_SIVM1 Simian immunodeficiency virus 4 0.7956
Class B acid phosphatase Q540U1 APHA_SALTM Salmonella typhimurium 2 0.7934
Class B acid phosphatase Q540U1 APHA_SALTM Salmonella typhimurium 2 0.7934
Disintegrin and metalloproteinase domain-containing protein 17 P78536 ADA17_HUMAN Homo sapiens 3 0.7917
Disintegrin and metalloproteinase domain-containing protein 17 P78536 ADA17_HUMAN Homo sapiens 3 0.7917
Beta-secretase 1 P56817 BACE1_HUMAN Homo sapiens 2 0.7863
Beta-secretase 1 P56817 BACE1_HUMAN Homo sapiens 2 0.7863
GCN5-related N-acetyltransferase B1YEL6 B1YEL6_EXIS2 Exiguobacterium sibiricum 3 0.7848
GCN5-related N-acetyltransferase B1YEL6 B1YEL6_EXIS2 Exiguobacterium sibiricum 3 0.7848
GCN5-related N-acetyltransferase B1YEL6 B1YEL6_EXIS2 Exiguobacterium sibiricum 3 0.7844
GCN5-related N-acetyltransferase B1YEL6 B1YEL6_EXIS2 Exiguobacterium sibiricum 3 0.7844
3',5'-cyclic-AMP phosphodiesterase 4D Q08499 PDE4D_HUMAN Homo sapiens 3 0.7836
3',5'-cyclic-AMP phosphodiesterase 4D Q08499 PDE4D_HUMAN Homo sapiens 3 0.7836
Beta-secretase 1 P56817 BACE1_HUMAN Homo sapiens 2 0.7783
Beta-secretase 1 P56817 BACE1_HUMAN Homo sapiens 2 0.7783
Tetracycline repressor protein class H P51561 TETR8_PASMD Pasteurella multocida 3 0.7782
Tetracycline repressor protein class H P51561 TETR8_PASMD Pasteurella multocida 3 0.7782
Thermolysin P00800 THER_BACTH Bacillus thermoproteolyticus 3 0.7781
Thermolysin P00800 THER_BACTH Bacillus thermoproteolyticus 3 0.7781
Polyribonucleotide nucleotidyltransferase A7ZS61 PNP_ECO24 Escherichia coli O139:H28 3 0.7780
Polyribonucleotide nucleotidyltransferase A7ZS61 PNP_ECO24 Escherichia coli O139:H28 3 0.7780
Nuclear receptor subfamily 1 group I member 2 O75469 NR1I2_HUMAN Homo sapiens 3 0.7747
Adenylate cyclase type 5 P30803 ADCY5_CANLF Canis lupus familiaris 3 0.7747
Nuclear receptor subfamily 1 group I member 2 O75469 NR1I2_HUMAN Homo sapiens 3 0.7747
Adenylate cyclase type 5 P30803 ADCY5_CANLF Canis lupus familiaris 3 0.7747
Basic phospholipase A2 VRV-PL-VIIIa P59071 PA2B8_DABRR Daboia russelii 3 0.7733
Basic phospholipase A2 VRV-PL-VIIIa P59071 PA2B8_DABRR Daboia russelii 3 0.7733
Agglutinin alpha chain P18674 LECA_MACPO Maclura pomifera 3 0.7692
Agglutinin alpha chain P18674 LECA_MACPO Maclura pomifera 3 0.7692
HTH-type transcriptional regulator EthR P9WMC1 ETHR_MYCTU Mycobacterium tuberculosis 3 0.7678
HTH-type transcriptional regulator EthR P9WMC1 ETHR_MYCTU Mycobacterium tuberculosis 3 0.7678
Mitogen-activated protein kinase 14 Q16539 MK14_HUMAN Homo sapiens 3 0.7651
Mitogen-activated protein kinase 14 Q16539 MK14_HUMAN Homo sapiens 3 0.7651
Ferrochelatase, mitochondrial P22830 HEMH_HUMAN Homo sapiens 3 0.7637
Ferrochelatase, mitochondrial P22830 HEMH_HUMAN Homo sapiens 3 0.7637
5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase P0AF12 MTNN_ECOLI Escherichia coli 3 0.7608
5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase P0AF12 MTNN_ECOLI Escherichia coli 3 0.7608
11-beta-hydroxysteroid dehydrogenase 1 P28845 DHI1_HUMAN Homo sapiens 3 0.7592
11-beta-hydroxysteroid dehydrogenase 1 P28845 DHI1_HUMAN Homo sapiens 3 0.7592
Glucan 1,3-beta-glucosidase P29717 EXG1_CANAL Candida albicans 3 0.7578
Glucan 1,3-beta-glucosidase P29717 EXG1_CANAL Candida albicans 3 0.7578
Gag-Pol polyprotein P04584 POL_HV2RO Human immunodeficiency virus type 2 subtype A 3 0.7548
Gag-Pol polyprotein P04584 POL_HV2RO Human immunodeficiency virus type 2 subtype A 3 0.7548
Tetracycline repressor protein class D P0ACT4 TETR4_ECOLX Escherichia coli 3 0.7531
Tetracycline repressor protein class D P0ACT4 TETR4_ECOLX Escherichia coli 3 0.7531
Tetracycline repressor protein class D P0ACT4 TETR4_ECOLX Escherichia coli 3 0.7526
Tetracycline repressor protein class D P0ACT4 TETR4_ECOLX Escherichia coli 3 0.7526
Lethal factor P15917 LEF_BACAN Bacillus anthracis 3 0.7500
Lethal factor P15917 LEF_BACAN Bacillus anthracis 3 0.7500
Tetracycline repressor protein class D P0ACT4 TETR4_ECOLX Escherichia coli 3 0.7489
Tetracycline repressor protein class D P0ACT4 TETR4_ECOLX Escherichia coli 3 0.7489
Beta-1 adrenergic receptor P07700 ADRB1_MELGA Meleagris gallopavo 2 0.7469
Beta-1 adrenergic receptor P07700 ADRB1_MELGA Meleagris gallopavo 2 0.7469
Pheromone-binding protein ASP1 Q9U9J6 Q9U9J6_APIME Apis mellifera 3 0.7443
Pheromone-binding protein ASP1 Q9U9J6 Q9U9J6_APIME Apis mellifera 3 0.7443
CCA-adding enzyme O28126 CCA_ARCFU Archaeoglobus fulgidus 2 0.7414
CCA-adding enzyme O28126 CCA_ARCFU Archaeoglobus fulgidus 2 0.7414
Caffeoyl-CoA O-methyltransferase Q40313 CAMT_MEDSA Medicago sativa 3 0.7413
Caffeoyl-CoA O-methyltransferase Q40313 CAMT_MEDSA Medicago sativa 3 0.7413
NADPH-dependent oxidoreductase 2-alkenal reductase Q39172 AER_ARATH Arabidopsis thaliana 2 0.7410
NADPH-dependent oxidoreductase 2-alkenal reductase Q39172 AER_ARATH Arabidopsis thaliana 2 0.7410
CmeR Q7B8P6 Q7B8P6_CAMJU Campylobacter jejuni 3 0.7408
CmeR Q7B8P6 Q7B8P6_CAMJU Campylobacter jejuni 3 0.7408
Tetracycline repressor protein class D P0ACT4 TETR4_ECOLX Escherichia coli 3 0.7406
Tetracycline repressor protein class D P0ACT4 TETR4_ECOLX Escherichia coli 3 0.7406
Mycocyclosin synthase P9WPP7 CP121_MYCTU Mycobacterium tuberculosis 2 0.7351
Mycocyclosin synthase P9WPP7 CP121_MYCTU Mycobacterium tuberculosis 2 0.7351
Flavoredoxin Q72HI0 Q72HI0_THET2 Thermus thermophilus 2 0.7350
Flavoredoxin Q72HI0 Q72HI0_THET2 Thermus thermophilus 2 0.7350
Mycinamicin III 3''-O-methyltransferase Q49492 MYCF_MICGR Micromonospora griseorubida 2 0.7335
Mycinamicin III 3''-O-methyltransferase Q49492 MYCF_MICGR Micromonospora griseorubida 2 0.7335
Nicotinamide phosphoribosyltransferase P43490 NAMPT_HUMAN Homo sapiens 3 0.7303
Nicotinamide phosphoribosyltransferase P43490 NAMPT_HUMAN Homo sapiens 3 0.7303
5-methylthioadenosine/S-adenosylhomocysteine deaminase Q7NZ90 Q7NZ90_CHRVO Chromobacterium violaceum 3 0.7300
5-methylthioadenosine/S-adenosylhomocysteine deaminase Q7NZ90 Q7NZ90_CHRVO Chromobacterium violaceum 3 0.7300
Tetracycline repressor protein class D P0ACT4 TETR4_ECOLX Escherichia coli 3 0.7296
Tetracycline repressor protein class D P0ACT4 TETR4_ECOLX Escherichia coli 3 0.7296
ABC-type polar amino acid transport system, ATPase component Q8RCC2 Q8RCC2_CALS4 Caldanaerobacter subterraneus subsp. tengcongensis 2 0.7288
ABC-type polar amino acid transport system, ATPase component Q8RCC2 Q8RCC2_CALS4 Caldanaerobacter subterraneus subsp. tengcongensis 2 0.7288
cAMP-dependent protein kinase type I-alpha regulatory subunit P00514 KAP0_BOVIN Bos taurus 2 0.7275
cAMP-dependent protein kinase type I-alpha regulatory subunit P00514 KAP0_BOVIN Bos taurus 2 0.7275
NAD(P) transhydrogenase subunit alpha part 1 Q2RSB2 PNTAA_RHORT Rhodospirillum rubrum 3 0.7269
NAD(P) transhydrogenase subunit alpha part 1 Q2RSB2 PNTAA_RHORT Rhodospirillum rubrum 3 0.7269
Multidrug efflux pump subunit AcrB P31224 ACRB_ECOLI Escherichia coli 3 0.7243
Multidrug efflux pump subunit AcrB P31224 ACRB_ECOLI Escherichia coli 3 0.7243
Oxygen-insensitive NAD(P)H nitroreductase P38489 NFSB_ECOLI Escherichia coli 4 0.7236
Oxygen-insensitive NAD(P)H nitroreductase P38489 NFSB_ECOLI Escherichia coli 4 0.7236
Tetracycline repressor protein class D P0ACT4 TETR4_ECOLX Escherichia coli 2 0.7233
Tetracycline repressor protein class D P0ACT4 TETR4_ECOLX Escherichia coli 2 0.7233
Carbonic anhydrase 1 P00915 CAH1_HUMAN Homo sapiens 2 0.7221
Carbonic anhydrase 1 P00915 CAH1_HUMAN Homo sapiens 2 0.7221
Chymotrypsinogen A P00766 CTRA_BOVIN Bos taurus 3 0.7220
Chymotrypsinogen A P00766 CTRA_BOVIN Bos taurus 3 0.7220
Bifunctional epoxide hydrolase 2 P34913 HYES_HUMAN Homo sapiens 2 0.7218
Bifunctional epoxide hydrolase 2 P34913 HYES_HUMAN Homo sapiens 2 0.7218
Carbonic anhydrase 4 Q64444 CAH4_MOUSE Mus musculus 2 0.7215
Carbonic anhydrase 4 Q64444 CAH4_MOUSE Mus musculus 2 0.7215
Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial Q33862 Q33862_ASCSU Ascaris suum 3 0.7206
Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial Q33862 Q33862_ASCSU Ascaris suum 3 0.7206
11-beta-hydroxysteroid dehydrogenase 1 P28845 DHI1_HUMAN Homo sapiens 3 0.7183
11-beta-hydroxysteroid dehydrogenase 1 P28845 DHI1_HUMAN Homo sapiens 3 0.7183
Tetracycline repressor protein class D P0ACT4 TETR4_ECOLX Escherichia coli 2 0.7181
Tetracycline repressor protein class D P0ACT4 TETR4_ECOLX Escherichia coli 2 0.7181
3',5'-cyclic-AMP phosphodiesterase 4D Q08499 PDE4D_HUMAN Homo sapiens 3 0.7176
3',5'-cyclic-AMP phosphodiesterase 4D Q08499 PDE4D_HUMAN Homo sapiens 3 0.7176
Methionine--tRNA ligase P00959 SYM_ECOLI Escherichia coli 3 0.7174
Methionine--tRNA ligase P00959 SYM_ECOLI Escherichia coli 3 0.7174
Dihydrofolate reductase P00378 DYR_CHICK Gallus gallus 2 0.7161
Dihydrofolate reductase P00378 DYR_CHICK Gallus gallus 2 0.7161
Photosynthetic reaction center cytochrome c subunit P07173 CYCR_BLAVI Blastochloris viridis 2 0.7155
Photosynthetic reaction center cytochrome c subunit P07173 CYCR_BLAVI Blastochloris viridis 2 0.7155
Acetylcholinesterase P04058 ACES_TETCF Tetronarce californica 3 0.7151
Coagulation factor X P00742 FA10_HUMAN Homo sapiens 2 0.7151
Acetylcholinesterase P04058 ACES_TETCF Tetronarce californica 3 0.7151
Coagulation factor X P00742 FA10_HUMAN Homo sapiens 2 0.7151
Tetracycline repressor protein class D P0ACT4 TETR4_ECOLX Escherichia coli 3 0.7150
Tetracycline repressor protein class D P0ACT4 TETR4_ECOLX Escherichia coli 3 0.7150
Methionine aminopeptidase P0AE18 MAP1_ECOLI Escherichia coli 3 0.7149
Methionine aminopeptidase P0AE18 MAP1_ECOLI Escherichia coli 3 0.7149
Vitamin D-binding protein P02774 VTDB_HUMAN Homo sapiens 2 0.7149
Vitamin D-binding protein P02774 VTDB_HUMAN Homo sapiens 2 0.7149
Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase Q9TQS6 DHDH_MACFA Macaca fascicularis 2 0.7132
Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase Q9TQS6 DHDH_MACFA Macaca fascicularis 2 0.7132
Bifunctional epoxide hydrolase 2 P34913 HYES_HUMAN Homo sapiens 4 0.7128
Bifunctional epoxide hydrolase 2 P34913 HYES_HUMAN Homo sapiens 4 0.7128
Adenosine kinase Q9TVW2 ADK_TOXGO Toxoplasma gondii 3 0.7124
Adenosine kinase Q9TVW2 ADK_TOXGO Toxoplasma gondii 3 0.7124
Tetracycline repressor protein class B from transposon Tn10 P04483 TETR2_ECOLX Escherichia coli 2 0.7112
Tetracycline repressor protein class B from transposon Tn10 P04483 TETR2_ECOLX Escherichia coli 2 0.7112
MAP kinase-activated protein kinase 2 P49137 MAPK2_HUMAN Homo sapiens 3 0.7105
MAP kinase-activated protein kinase 2 P49137 MAPK2_HUMAN Homo sapiens 3 0.7105
Cytochrome P450 S6BVH1 S6BVH1_RHOER Rhodococcus erythropolis 3 0.7082
Cytochrome P450 S6BVH1 S6BVH1_RHOER Rhodococcus erythropolis 3 0.7082
Tetracycline repressor protein class D P0ACT4 TETR4_ECOLX Escherichia coli 2 0.7073
Tetracycline repressor protein class D P0ACT4 TETR4_ECOLX Escherichia coli 2 0.7073
Chloramphenicol 3-O phosphotransferase Q56148 CPT_STRVP Streptomyces venezuelae 3 0.7068
Chloramphenicol 3-O phosphotransferase Q56148 CPT_STRVP Streptomyces venezuelae 3 0.7068
Avidin P02701 AVID_CHICK Gallus gallus 2 0.7061
Avidin P02701 AVID_CHICK Gallus gallus 2 0.7061
Retinoic acid receptor RXR-alpha P19793 RXRA_HUMAN Homo sapiens 2 0.7055
Retinoic acid receptor RXR-alpha P19793 RXRA_HUMAN Homo sapiens 2 0.7055
Tetracycline repressor protein class D P0ACT4 TETR4_ECOLX Escherichia coli 2 0.7048
Tetracycline repressor protein class D P0ACT4 TETR4_ECOLX Escherichia coli 2 0.7048
Pantothenate kinase P9WPA7 COAA_MYCTU Mycobacterium tuberculosis 3 0.7047
Pantothenate kinase P9WPA7 COAA_MYCTU Mycobacterium tuberculosis 3 0.7047
Multidrug efflux pump subunit AcrB P31224 ACRB_ECOLI Escherichia coli 3 0.7045
Multidrug efflux pump subunit AcrB P31224 ACRB_ECOLI Escherichia coli 3 0.7045
Ras-related protein Ral-B P11234 RALB_HUMAN Homo sapiens 2 0.7029
Ras-related protein Ral-B P11234 RALB_HUMAN Homo sapiens 2 0.7029
Carbonic anhydrase 2 P00918 CAH2_HUMAN Homo sapiens 2 0.7021
Carbonic anhydrase 2 P00918 CAH2_HUMAN Homo sapiens 2 0.7021
F420-dependent methylenetetrahydromethanopterin dehydrogenase P94951 MTD_METKA Methanopyrus kandleri 2 0.7001
F420-dependent methylenetetrahydromethanopterin dehydrogenase P94951 MTD_METKA Methanopyrus kandleri 2 0.7001

Download SDF