2-methyl-5-(4'(S)-hydroxy-1'(R),5'-dimethylhex-5'-enyl)-phenol - Compound Card

2-methyl-5-(4'(S)-hydroxy-1'(R),5'-dimethylhex-5'-enyl)-phenol

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2-methyl-5-(4'(S)-hydroxy-1'(R),5'-dimethylhex-5'-enyl)-phenol

Structure
Zoomed Structure
  • Family: Plantae - Burseraceae
  • Kingdom: Plantae
  • Class: Monoaromatic
Canonical Smiles CC(=C)[C@H](CC[C@H](c1ccc(c(c1)O)C)C)O
InChI InChI=1S/C15H22O2/c1-10(2)14(16)8-6-11(3)13-7-5-12(4)15(17)9-13/h5,7,9,11,14,16-17H,1,6,8H2,2-4H3/t11-,14+/m1/s1
InChIKey CDFYSXHPCPFPAR-RISCZKNCSA-N
Formula C15H22O2
HBA 2
HBD 2
MW 234.34
Rotatable Bonds 5
TPSA 40.46
LogP 3.52
Number Rings 1
Number Aromatic Rings 1
Heavy Atom Count 17
Formal Charge 0
Fraction CSP3 0.47
Exact Mass 234.16
Number of Lipinski Rule Violations 0
# Species Family Kingdom NCBI Taxonomy ID
1 Commiphora kua Burseraceae Plantae 246356

Showing of synonyms

  • Manguro LO, Ugi I, et al. (2003). Further bisabolenes and dammarane triterpenes of Commiphora kua resin.. Chemical and Pharmaceutical Bulletin,2003,51(5),479-482. [View] [PubMed]
Pubchem: 90825601

No compound-protein relationship available.

Structure

SMILES: c1ccccc1

Level: 0

Mol. Weight: 234.34 g/mol

No bioactivities available.

Absorption

Caco-2 (logPapp)
-4.63
Human Oral Bioavailability 20%
Bioavailable
Human Intestinal Absorption
Absorbed
Madin-Darby Canine Kidney
-4.19
Human Oral Bioavailability 50%
Bioavailable
P-Glycoprotein Inhibitor
Non-Inhibitor
P-Glycoprotein Substrate
Non-Substrate
Skin Permeability
-2.77

Distribution

Blood-Brain Barrier (CNS)
-
Blood-Brain Barrier
Penetrable
Fraction Unbound (Human)
0.33
Plasma Protein Binding
58.56
Steady State Volume of Distribution
-

Metabolism

Breast Cancer Resistance Protein
Non-Inhibitor
CYP 1A2 Inhibitor
Inhibitor
CYP 1A2 Substrate
Substrate
CYP 2C19 Inhibitor
Non-Inhibitor
CYP 2C19 Substrate
Substrate
CYP 2C9 Inhibitor
Non-Inhibitor
CYP 2C9 Substrate
Substrate
CYP 2D6 Inhibitor
Non-Inhibitor
CYP 2D6 Substrate
Substrate
CYP 3A4 Inhibitor
Non-Inhibitor
CYP 3A4 Substrate
Substrate
OATP1B1
Non-Inhibitor
OATP1B3
Non-Inhibitor

Excretion

Clearance
10.9
Organic Cation Transporter 2
Non-Inhibitor
Half-Life of Drug
-

Toxicity

AMES Mutagenesis
Safe
Avian
Safe
Bee
Toxic
Bioconcentration Factor
0.84
Biodegradation
Safe
Carcinogenesis
Toxic
Crustacean
Safe
Liver Injury I (DILI)
Safe
Eye Corrosion
Safe
Eye Irritation
Safe
Maximum Tolerated Dose
-0.41
Liver Injury II
Safe
hERG Blockers
Safe
Daphnia Maga
4.91
Micronucleos
Safe
NR-AhR
Safe
NR-AR
Safe
NR-AR-LBD
Safe
NR-Aromatase
Safe
NR-ER
Safe
NR-ER-LBD
Safe
NR-GR
Safe
NR-PPAR-gamma
Safe
NR-TR
Safe
T. Pyriformis
0.72
Rat (Acute)
2.09
Rat (Chronic Oral)
1.92
Fathead Minnow
3.99
Respiratory Disease
Toxic
Skin Sensitisation
Toxic
SR-ARE
Safe
SR-ATAD5
Safe
SR-HSE
Safe
SR-MMP
Toxic
SR-p53
Safe

General Properties

Boiling Point
304.77
Hydration Free Energy
-7.45
Log(D) at pH=7.4
2.67
Log(P)
3.67
Log S
-3.26
Log(Vapor Pressure)
-4.8
Melting Point
88.16
pKa Acid
10.73
pKa Basic
5.08
Protein Name UniProt ID Entry Name Species #Pharmacophore Points Probability (0.7 ≤ Tversky Score ≤ 1.0)
Rhodopsin P02699 OPSD_BOVIN Bos taurus 3 0.9560
Rhodopsin P02699 OPSD_BOVIN Bos taurus 3 0.9560
Odorant-binding protein P81245 OBP_PIG Sus scrofa 3 0.9466
Odorant-binding protein P81245 OBP_PIG Sus scrofa 3 0.9466
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 P04191 AT2A1_RABIT Oryctolagus cuniculus 3 0.9312
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 P04191 AT2A1_RABIT Oryctolagus cuniculus 3 0.9312
Chitinase Q54276 Q54276_SERMA Serratia marcescens 3 0.9221
Chitinase Q54276 Q54276_SERMA Serratia marcescens 3 0.9221
3',5'-cyclic-AMP phosphodiesterase 4D Q08499 PDE4D_HUMAN Homo sapiens 3 0.9171
3',5'-cyclic-AMP phosphodiesterase 4D Q08499 PDE4D_HUMAN Homo sapiens 3 0.9171
Albumin P02768 ALBU_HUMAN Homo sapiens 3 0.9139
Albumin P02768 ALBU_HUMAN Homo sapiens 3 0.9139
CmeR Q7B8P6 Q7B8P6_CAMJU Campylobacter jejuni 3 0.9051
CmeR Q7B8P6 Q7B8P6_CAMJU Campylobacter jejuni 3 0.9051
Thiosulfate reductase Q72LA4 Q72LA4_THET2 Thermus thermophilus 4 0.8939
Thiosulfate reductase Q72LA4 Q72LA4_THET2 Thermus thermophilus 4 0.8939
3',5'-cyclic-AMP phosphodiesterase 4D Q08499 PDE4D_HUMAN Homo sapiens 3 0.8917
3',5'-cyclic-AMP phosphodiesterase 4D Q08499 PDE4D_HUMAN Homo sapiens 3 0.8917
Phytohormone-binding protein CSBP A0A1S3THR8 PHBP_VIGRR Vigna radiata var. radiata 3 0.8896
Phytohormone-binding protein CSBP A0A1S3THR8 PHBP_VIGRR Vigna radiata var. radiata 3 0.8896
Envelope glycoprotein gp160 Q0ED31 Q0ED31_9HIV1 Human immunodeficiency virus 1 3 0.8859
Envelope glycoprotein gp160 Q0ED31 Q0ED31_9HIV1 Human immunodeficiency virus 1 3 0.8859
Mycinamicin III 3''-O-methyltransferase Q49492 MYCF_MICGR Micromonospora griseorubida 2 0.8849
Mycinamicin III 3''-O-methyltransferase Q49492 MYCF_MICGR Micromonospora griseorubida 2 0.8849
cGMP-dependent 3',5'-cyclic phosphodiesterase O00408 PDE2A_HUMAN Homo sapiens 3 0.8785
cGMP-dependent 3',5'-cyclic phosphodiesterase O00408 PDE2A_HUMAN Homo sapiens 3 0.8785
3',5'-cyclic-AMP phosphodiesterase 4D Q08499 PDE4D_HUMAN Homo sapiens 3 0.8762
3',5'-cyclic-AMP phosphodiesterase 4D Q08499 PDE4D_HUMAN Homo sapiens 3 0.8762
Nitric oxide synthase, inducible P29477 NOS2_MOUSE Mus musculus 3 0.8751
Nitric oxide synthase, inducible P29477 NOS2_MOUSE Mus musculus 3 0.8751
Aldo-keto reductase family 1 member C3 P42330 AK1C3_HUMAN Homo sapiens 5 0.8703
Aldo-keto reductase family 1 member C3 P42330 AK1C3_HUMAN Homo sapiens 5 0.8703
NAD-capped RNA hydrolase NudC P32664 NUDC_ECOLI Escherichia coli 3 0.8681
NAD-capped RNA hydrolase NudC P32664 NUDC_ECOLI Escherichia coli 3 0.8681
Beta-secretase 1 P56817 BACE1_HUMAN Homo sapiens 3 0.8588
Beta-secretase 1 P56817 BACE1_HUMAN Homo sapiens 3 0.8588
Nuclear receptor subfamily 1 group I member 3 O35627 NR1I3_MOUSE Mus musculus 3 0.8549
Nuclear receptor subfamily 1 group I member 3 O35627 NR1I3_MOUSE Mus musculus 3 0.8549
Ferrochelatase, mitochondrial P22830 HEMH_HUMAN Homo sapiens 3 0.8520
Ferrochelatase, mitochondrial P22830 HEMH_HUMAN Homo sapiens 3 0.8520
Retinol dehydratase Q26490 Q26490_SPOFR Spodoptera frugiperda 3 0.8504
Retinol dehydratase Q26490 Q26490_SPOFR Spodoptera frugiperda 3 0.8504
Gastrotropin P51161 FABP6_HUMAN Homo sapiens 3 0.8499
Gastrotropin P51161 FABP6_HUMAN Homo sapiens 3 0.8499
Casein kinase II subunit alpha' P19784 CSK22_HUMAN Homo sapiens 3 0.8485
Casein kinase II subunit alpha' P19784 CSK22_HUMAN Homo sapiens 3 0.8485
Photosynthetic reaction center cytochrome c subunit P07173 CYCR_BLAVI Blastochloris viridis 3 0.8484
Photosynthetic reaction center cytochrome c subunit P07173 CYCR_BLAVI Blastochloris viridis 3 0.8484
Aldo-keto reductase family 1 member C3 P42330 AK1C3_HUMAN Homo sapiens 3 0.8479
Aldo-keto reductase family 1 member C3 P42330 AK1C3_HUMAN Homo sapiens 3 0.8479
Retinoic acid receptor RXR-alpha P19793 RXRA_HUMAN Homo sapiens 3 0.8466
Retinoic acid receptor RXR-alpha P19793 RXRA_HUMAN Homo sapiens 3 0.8466
Soluble acetylcholine receptor Q8WSF8 Q8WSF8_APLCA Aplysia californica 3 0.8412
Soluble acetylcholine receptor Q8WSF8 Q8WSF8_APLCA Aplysia californica 3 0.8412
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A Q9Y233 PDE10_HUMAN Homo sapiens 3 0.8408
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A Q9Y233 PDE10_HUMAN Homo sapiens 3 0.8408
Succinate dehydrogenase flavoprotein subunit P0AC41 SDHA_ECOLI Escherichia coli 3 0.8397
Succinate dehydrogenase flavoprotein subunit P0AC41 SDHA_ECOLI Escherichia coli 3 0.8397
Acetylcholinesterase P21836 ACES_MOUSE Mus musculus 3 0.8388
Acetylcholinesterase P21836 ACES_MOUSE Mus musculus 3 0.8388
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 P04191 AT2A1_RABIT Oryctolagus cuniculus 3 0.8385
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 P04191 AT2A1_RABIT Oryctolagus cuniculus 3 0.8385
Corticosteroid-binding globulin P08185 CBG_HUMAN Homo sapiens 3 0.8372
Corticosteroid-binding globulin P08185 CBG_HUMAN Homo sapiens 3 0.8372
Nitric oxide synthase, inducible P29477 NOS2_MOUSE Mus musculus 3 0.8354
Nitric oxide synthase, inducible P29477 NOS2_MOUSE Mus musculus 3 0.8354
Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase F6MZ55 F6MZ55_9FIRM Sporomusa ovata 3 0.8284
Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase F6MZ55 F6MZ55_9FIRM Sporomusa ovata 3 0.8284
17-beta-hydroxysteroid dehydrogenase type 1 P14061 DHB1_HUMAN Homo sapiens 3 0.8275
17-beta-hydroxysteroid dehydrogenase type 1 P14061 DHB1_HUMAN Homo sapiens 3 0.8275
AGAP003309-PA A0A1U7F4W2 A0A1U7F4W2_ANOGA Anopheles gambiae 3 0.8273
AGAP003309-PA A0A1U7F4W2 A0A1U7F4W2_ANOGA Anopheles gambiae 3 0.8273
Sulfotransferase 2B1 O00204 ST2B1_HUMAN Homo sapiens 2 0.8222
Sulfotransferase 2B1 O00204 ST2B1_HUMAN Homo sapiens 2 0.8222
Bacteriorhodopsin P02945 BACR_HALSA Halobacterium salinarum 3 0.8216
Bacteriorhodopsin P02945 BACR_HALSA Halobacterium salinarum 3 0.8216
Probable NDP-rhamnosyltransferase Q9ALM8 Q9ALM8_SACSN Saccharopolyspora spinosa 3 0.8197
Probable NDP-rhamnosyltransferase Q9ALM8 Q9ALM8_SACSN Saccharopolyspora spinosa 3 0.8197
3-ketosteroid dehydrogenase Q9RA02 Q9RA02_RHOER Rhodococcus erythropolis 2 0.8194
3-ketosteroid dehydrogenase Q9RA02 Q9RA02_RHOER Rhodococcus erythropolis 2 0.8194
Beta-1 adrenergic receptor P07700 ADRB1_MELGA Meleagris gallopavo 3 0.8173
Beta-1 adrenergic receptor P07700 ADRB1_MELGA Meleagris gallopavo 3 0.8173
Bifunctional dihydrofolate reductase-thymidylate synthase P13922 DRTS_PLAFK Plasmodium falciparum 3 0.8172
Bifunctional dihydrofolate reductase-thymidylate synthase P13922 DRTS_PLAFK Plasmodium falciparum 3 0.8172
Sex hormone-binding globulin P04278 SHBG_HUMAN Homo sapiens 3 0.8142
Sex hormone-binding globulin P04278 SHBG_HUMAN Homo sapiens 3 0.8142
Japanin M1MR49 M1MR49_RHIAP Rhipicephalus appendiculatus 3 0.8087
Japanin M1MR49 M1MR49_RHIAP Rhipicephalus appendiculatus 3 0.8087
Nitric oxide synthase, inducible P29477 NOS2_MOUSE Mus musculus 3 0.8080
Nitric oxide synthase, inducible P29477 NOS2_MOUSE Mus musculus 3 0.8080
Soluble acetylcholine receptor Q8WSF8 Q8WSF8_APLCA Aplysia californica 3 0.8079
Soluble acetylcholine receptor Q8WSF8 Q8WSF8_APLCA Aplysia californica 3 0.8079
Beta-galactoside-specific lectin 1 P81446 ML1_VISAL Viscum album 3 0.8061
Beta-galactoside-specific lectin 1 P81446 ML1_VISAL Viscum album 3 0.8061
Aldo-keto reductase family 1 member C2 P52895 AK1C2_HUMAN Homo sapiens 3 0.8052
Aldo-keto reductase family 1 member C2 P52895 AK1C2_HUMAN Homo sapiens 3 0.8052
Heat shock protein HSP 90-alpha P07900 HS90A_HUMAN Homo sapiens 3 0.8051
Heat shock protein HSP 90-alpha P07900 HS90A_HUMAN Homo sapiens 3 0.8051
Gag-Pol polyprotein P03366 POL_HV1B1 Human immunodeficiency virus type 1 group M subtype B 3 0.8044
Gag-Pol polyprotein P03366 POL_HV1B1 Human immunodeficiency virus type 1 group M subtype B 3 0.8044
GCN5-related N-acetyltransferase B1YEL6 B1YEL6_EXIS2 Exiguobacterium sibiricum 3 0.8018
GCN5-related N-acetyltransferase B1YEL6 B1YEL6_EXIS2 Exiguobacterium sibiricum 3 0.8018
GCN5-related N-acetyltransferase B1YEL6 B1YEL6_EXIS2 Exiguobacterium sibiricum 3 0.7997
GCN5-related N-acetyltransferase B1YEL6 B1YEL6_EXIS2 Exiguobacterium sibiricum 3 0.7997
Cytochrome P450 Q93H81 Q93H81_STRAX Streptomyces avermitilis 3 0.7954
Cytochrome P450 Q93H81 Q93H81_STRAX Streptomyces avermitilis 3 0.7954
Nitric oxide synthase, inducible P29477 NOS2_MOUSE Mus musculus 3 0.7949
Nitric oxide synthase, inducible P29477 NOS2_MOUSE Mus musculus 3 0.7949
Peptidyl-prolyl cis-trans isomerase FKBP1A P62942 FKB1A_HUMAN Homo sapiens 2 0.7931
Peptidyl-prolyl cis-trans isomerase FKBP1A P62942 FKB1A_HUMAN Homo sapiens 2 0.7931
Sulfide-quinone reductase B7JBP8 SQRD_ACIF2 Acidithiobacillus ferrooxidans) 3 0.7925
Sulfide-quinone reductase B7JBP8 SQRD_ACIF2 Acidithiobacillus ferrooxidans) 3 0.7925
Retinol-binding protein 1 P09455 RET1_HUMAN Homo sapiens 3 0.7880
Retinol-binding protein 1 P09455 RET1_HUMAN Homo sapiens 3 0.7880
Bifunctional dihydrofolate reductase-thymidylate synthase Q27793 DRTS_TRYCR Trypanosoma cruzi 3 0.7873
Bifunctional dihydrofolate reductase-thymidylate synthase Q27793 DRTS_TRYCR Trypanosoma cruzi 3 0.7873
High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A O76083 PDE9A_HUMAN Homo sapiens 3 0.7861
High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A O76083 PDE9A_HUMAN Homo sapiens 3 0.7861
Estrogen receptor P03372 ESR1_HUMAN Homo sapiens 3 0.7846
Estrogen receptor P03372 ESR1_HUMAN Homo sapiens 3 0.7846
Aldo-keto reductase family 1 member D1 P51857 AK1D1_HUMAN Homo sapiens 2 0.7834
Aldo-keto reductase family 1 member D1 P51857 AK1D1_HUMAN Homo sapiens 2 0.7834
Carbonic anhydrase 2 P00918 CAH2_HUMAN Homo sapiens 3 0.7820
Carbonic anhydrase 2 P00918 CAH2_HUMAN Homo sapiens 3 0.7820
Serine/threonine-protein kinase Chk1 O14757 CHK1_HUMAN Homo sapiens 3 0.7819
Serine/threonine-protein kinase Chk1 O14757 CHK1_HUMAN Homo sapiens 3 0.7819
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 P04191 AT2A1_RABIT Oryctolagus cuniculus 3 0.7811
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 P04191 AT2A1_RABIT Oryctolagus cuniculus 3 0.7811
Histone deacetylase 8 Q9BY41 HDAC8_HUMAN Homo sapiens 2 0.7807
Histone deacetylase 8 Q9BY41 HDAC8_HUMAN Homo sapiens 2 0.7807
Steroid Delta-isomerase P07445 SDIS_PSEPU Pseudomonas putida 3 0.7786
Steroid Delta-isomerase P07445 SDIS_PSEPU Pseudomonas putida 3 0.7786
Steroid Delta-isomerase P00947 SDIS_COMTE Comamonas testosteroni 2 0.7774
Steroid Delta-isomerase P00947 SDIS_COMTE Comamonas testosteroni 2 0.7774
cAMP-dependent protein kinase catalytic subunit alpha P17612 KAPCA_HUMAN Homo sapiens 3 0.7764
cAMP-dependent protein kinase catalytic subunit alpha P17612 KAPCA_HUMAN Homo sapiens 3 0.7764
Fatty acid-binding protein, liver P80226 FABPL_CHICK Gallus gallus 3 0.7756
Fatty acid-binding protein, liver P80226 FABPL_CHICK Gallus gallus 3 0.7756
Mycinamicin III 3''-O-methyltransferase Q49492 MYCF_MICGR Micromonospora griseorubida 2 0.7753
Mycinamicin III 3''-O-methyltransferase Q49492 MYCF_MICGR Micromonospora griseorubida 2 0.7753
TDP-4-oxo-6-deoxy-alpha-D-glucose-3,4-oxoisomerase Q6T1W8 FDTA_ANETH Aneurinibacillus thermoaerophilus 3 0.7750
TDP-4-oxo-6-deoxy-alpha-D-glucose-3,4-oxoisomerase Q6T1W8 FDTA_ANETH Aneurinibacillus thermoaerophilus 3 0.7750
Gag-Pol polyprotein P03366 POL_HV1B1 Human immunodeficiency virus type 1 group M subtype B 3 0.7741
Gag-Pol polyprotein P03366 POL_HV1B1 Human immunodeficiency virus type 1 group M subtype B 3 0.7741
3',5'-cyclic-AMP phosphodiesterase 4D Q08499 PDE4D_HUMAN Homo sapiens 2 0.7739
3',5'-cyclic-AMP phosphodiesterase 4D Q08499 PDE4D_HUMAN Homo sapiens 2 0.7739
Major pollen allergen Bet v 1-A P15494 BEV1A_BETPN Betula pendula 3 0.7717
Major pollen allergen Bet v 1-A P15494 BEV1A_BETPN Betula pendula 3 0.7717
Cytochrome P450 S6BVH1 S6BVH1_RHOER Rhodococcus erythropolis 3 0.7715
Cytochrome P450 S6BVH1 S6BVH1_RHOER Rhodococcus erythropolis 3 0.7715
Beta-elicitin cryptogein P15570 ELIB_PHYCR Phytophthora cryptogea 3 0.7702
Beta-elicitin cryptogein P15570 ELIB_PHYCR Phytophthora cryptogea 3 0.7702
Succinate dehydrogenase flavoprotein subunit P0AC41 SDHA_ECOLI Escherichia coli 3 0.7700
Succinate dehydrogenase flavoprotein subunit P0AC41 SDHA_ECOLI Escherichia coli 3 0.7700
Carbonic anhydrase 2 P00918 CAH2_HUMAN Homo sapiens 2 0.7693
Carbonic anhydrase 2 P00918 CAH2_HUMAN Homo sapiens 2 0.7693
Ferrochelatase, mitochondrial P22830 HEMH_HUMAN Homo sapiens 2 0.7676
Ferrochelatase, mitochondrial P22830 HEMH_HUMAN Homo sapiens 2 0.7676
Beta-secretase 1 P56817 BACE1_HUMAN Homo sapiens 2 0.7674
Beta-secretase 1 P56817 BACE1_HUMAN Homo sapiens 2 0.7674
Casein kinase II subunit alpha P68400 CSK21_HUMAN Homo sapiens 3 0.7670
Casein kinase II subunit alpha P68400 CSK21_HUMAN Homo sapiens 3 0.7670
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 P04191 AT2A1_RABIT Oryctolagus cuniculus 3 0.7649
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 P04191 AT2A1_RABIT Oryctolagus cuniculus 3 0.7649
Lethal(3)malignant brain tumor-like protein 1 Q9Y468 LMBL1_HUMAN Homo sapiens 3 0.7646
Aldo-keto reductase family 1 member C2 P52895 AK1C2_HUMAN Homo sapiens 2 0.7646
Lethal(3)malignant brain tumor-like protein 1 Q9Y468 LMBL1_HUMAN Homo sapiens 3 0.7646
Aldo-keto reductase family 1 member C2 P52895 AK1C2_HUMAN Homo sapiens 2 0.7646
Heat shock protein HSP 90-alpha P07900 HS90A_HUMAN Homo sapiens 3 0.7645
Heat shock protein HSP 90-alpha P07900 HS90A_HUMAN Homo sapiens 3 0.7645
Pentaerythritol tetranitrate reductase P71278 P71278_ENTCL Enterobacter cloacae 3 0.7644
Pentaerythritol tetranitrate reductase P71278 P71278_ENTCL Enterobacter cloacae 3 0.7644
Jasmonoyl--L-amino acid synthetase JAR1 Q9SKE2 JAR1_ARATH Arabidopsis thaliana 3 0.7644
Jasmonoyl--L-amino acid synthetase JAR1 Q9SKE2 JAR1_ARATH Arabidopsis thaliana 3 0.7644
ActVA 6 protein Q53908 Q53908_STRCH Streptomyces coelicolor 3 0.7643
Nuclear receptor subfamily 1 group I member 2 O75469 NR1I2_HUMAN Homo sapiens 3 0.7643
ActVA 6 protein Q53908 Q53908_STRCH Streptomyces coelicolor 3 0.7643
Nuclear receptor subfamily 1 group I member 2 O75469 NR1I2_HUMAN Homo sapiens 3 0.7643
Ribosyldihydronicotinamide dehydrogenase [quinone] P16083 NQO2_HUMAN Homo sapiens 3 0.7638
Ribosyldihydronicotinamide dehydrogenase [quinone] P16083 NQO2_HUMAN Homo sapiens 3 0.7638
Aldo-keto reductase family 1 member D1 P51857 AK1D1_HUMAN Homo sapiens 2 0.7633
Aldo-keto reductase family 1 member D1 P51857 AK1D1_HUMAN Homo sapiens 2 0.7633
Steroid Delta-isomerase P07445 SDIS_PSEPU Pseudomonas putida 2 0.7627
Steroid Delta-isomerase P07445 SDIS_PSEPU Pseudomonas putida 2 0.7627
High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A O76083 PDE9A_HUMAN Homo sapiens 3 0.7612
High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A O76083 PDE9A_HUMAN Homo sapiens 3 0.7612
CmeR Q7B8P6 Q7B8P6_CAMJU Campylobacter jejuni 2 0.7610
CmeR Q7B8P6 Q7B8P6_CAMJU Campylobacter jejuni 2 0.7610
Achbp I6L8L2 I6L8L2_CAPTE Capitella teleta 3 0.7594
Achbp I6L8L2 I6L8L2_CAPTE Capitella teleta 3 0.7594
Scytalone dehydratase P56221 SCYD_MAGO7 Pyricularia oryzae 3 0.7593
Scytalone dehydratase P56221 SCYD_MAGO7 Pyricularia oryzae 3 0.7593
Bromodomain adjacent to zinc finger domain protein 2B Q9UIF8 BAZ2B_HUMAN Homo sapiens 2 0.7587
Bromodomain adjacent to zinc finger domain protein 2B Q9UIF8 BAZ2B_HUMAN Homo sapiens 2 0.7587
Tetracycline repressor protein class D P0ACT4 TETR4_ECOLX Escherichia coli 3 0.7581
Serine/threonine-protein kinase Chk2 O96017 CHK2_HUMAN Homo sapiens 3 0.7581
Serine/threonine-protein kinase Chk2 O96017 CHK2_HUMAN Homo sapiens 3 0.7581
Tetracycline repressor protein class D P0ACT4 TETR4_ECOLX Escherichia coli 3 0.7581
Genome polyprotein P26663 POLG_HCVBK Hepatitis C virus genotype 1b 3 0.7578
Genome polyprotein P26663 POLG_HCVBK Hepatitis C virus genotype 1b 3 0.7578
Scytalone dehydratase P56221 SCYD_MAGO7 Pyricularia oryzae 3 0.7570
Scytalone dehydratase P56221 SCYD_MAGO7 Pyricularia oryzae 3 0.7570
2,7-dihydroxy-5-methyl-1-naphthoate 7-O-methyltransferase Q84HC8 NCSB1_STRCZ Streptomyces carzinostaticus 2 0.7564
2,7-dihydroxy-5-methyl-1-naphthoate 7-O-methyltransferase Q84HC8 NCSB1_STRCZ Streptomyces carzinostaticus 2 0.7564
Cyclin-dependent kinase 2 P24941 CDK2_HUMAN Homo sapiens 3 0.7557
Cyclin-dependent kinase 2 P24941 CDK2_HUMAN Homo sapiens 3 0.7557
Androgen receptor P10275 ANDR_HUMAN Homo sapiens 3 0.7556
Androgen receptor P10275 ANDR_HUMAN Homo sapiens 3 0.7556
Nitric oxide synthase, inducible P29477 NOS2_MOUSE Mus musculus 3 0.7547
Nitric oxide synthase, inducible P29477 NOS2_MOUSE Mus musculus 3 0.7547
Aldo-keto reductase family 1 member C2 P52895 AK1C2_HUMAN Homo sapiens 2 0.7546
Aldo-keto reductase family 1 member C2 P52895 AK1C2_HUMAN Homo sapiens 2 0.7546
Lactoylglutathione lyase Q9CPU0 LGUL_MOUSE Mus musculus 2 0.7545
Lactoylglutathione lyase Q9CPU0 LGUL_MOUSE Mus musculus 2 0.7545
Aldo-keto reductase family 1 member C2 P52895 AK1C2_HUMAN Homo sapiens 2 0.7542
Aldo-keto reductase family 1 member C2 P52895 AK1C2_HUMAN Homo sapiens 2 0.7542
Endothiapepsin P11838 CARP_CRYPA Cryphonectria parasitica 2 0.7531
Endothiapepsin P11838 CARP_CRYPA Cryphonectria parasitica 2 0.7531
Lanosterol synthase P48449 ERG7_HUMAN Homo sapiens 3 0.7529
Lanosterol synthase P48449 ERG7_HUMAN Homo sapiens 3 0.7529
Aldo-keto reductase family 1 member C2 P52895 AK1C2_HUMAN Homo sapiens 2 0.7523
Aldo-keto reductase family 1 member C2 P52895 AK1C2_HUMAN Homo sapiens 2 0.7523
Sulfotransferase 2A1 Q06520 ST2A1_HUMAN Homo sapiens 3 0.7509
Sulfotransferase 2A1 Q06520 ST2A1_HUMAN Homo sapiens 3 0.7509
Bromodomain-containing protein 4 O60885 BRD4_HUMAN Homo sapiens 3 0.7502
Bromodomain-containing protein 4 O60885 BRD4_HUMAN Homo sapiens 3 0.7502
Purine nucleoside phosphorylase DeoD-type Q5EEL8 DEOD_BACCE Bacillus cereus 3 0.7501
Purine nucleoside phosphorylase DeoD-type Q5EEL8 DEOD_BACCE Bacillus cereus 3 0.7501
Aldo-keto reductase family 1 member C2 P52895 AK1C2_HUMAN Homo sapiens 2 0.7497
Aldo-keto reductase family 1 member C2 P52895 AK1C2_HUMAN Homo sapiens 2 0.7497
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 P04191 AT2A1_RABIT Oryctolagus cuniculus 2 0.7490
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 P04191 AT2A1_RABIT Oryctolagus cuniculus 2 0.7490
Beta-1 adrenergic receptor P07700 ADRB1_MELGA Meleagris gallopavo 2 0.7485
Beta-1 adrenergic receptor P07700 ADRB1_MELGA Meleagris gallopavo 2 0.7485
Thiamine-phosphate synthase P39594 THIE_BACSU Bacillus subtilis 3 0.7480
Thiamine-phosphate synthase P39594 THIE_BACSU Bacillus subtilis 3 0.7480
Ferrochelatase, mitochondrial P22830 HEMH_HUMAN Homo sapiens 3 0.7478
Ferrochelatase, mitochondrial P22830 HEMH_HUMAN Homo sapiens 3 0.7478
Acetylcholinesterase P21836 ACES_MOUSE Mus musculus 3 0.7474
Acetylcholinesterase P21836 ACES_MOUSE Mus musculus 3 0.7474
Retinoic acid receptor RXR Q8T5C6 RXR_BIOGL Biomphalaria glabrata 3 0.7465
Retinoic acid receptor RXR Q8T5C6 RXR_BIOGL Biomphalaria glabrata 3 0.7465
Abscisic acid receptor PYL3 Q9SSM7 PYL3_ARATH Arabidopsis thaliana 3 0.7458
Abscisic acid receptor PYL3 Q9SSM7 PYL3_ARATH Arabidopsis thaliana 3 0.7458
Ribosyldihydronicotinamide dehydrogenase [quinone] P16083 NQO2_HUMAN Homo sapiens 3 0.7457
Ribosyldihydronicotinamide dehydrogenase [quinone] P16083 NQO2_HUMAN Homo sapiens 3 0.7457
Phospholipase A2, major isoenzyme P00592 PA21B_PIG Sus scrofa 4 0.7443
Phospholipase A2, major isoenzyme P00592 PA21B_PIG Sus scrofa 4 0.7443
3',5'-cyclic-AMP phosphodiesterase 4D Q08499 PDE4D_HUMAN Homo sapiens 3 0.7438
3',5'-cyclic-AMP phosphodiesterase 4D Q08499 PDE4D_HUMAN Homo sapiens 3 0.7438
Glutathione S-transferase A1 P08263 GSTA1_HUMAN Homo sapiens 2 0.7433
Glutathione S-transferase A1 P08263 GSTA1_HUMAN Homo sapiens 2 0.7433
Beta-1 adrenergic receptor P07700 ADRB1_MELGA Meleagris gallopavo 3 0.7430
Beta-1 adrenergic receptor P07700 ADRB1_MELGA Meleagris gallopavo 3 0.7430
Chitinase A Q9AMP1 Q9AMP1_VIBHA Vibrio harveyi 2 0.7429
Chitinase A Q9AMP1 Q9AMP1_VIBHA Vibrio harveyi 2 0.7429
Alcohol dehydrogenase E chain P00327 ADH1E_HORSE Equus caballus 3 0.7426
Alcohol dehydrogenase E chain P00327 ADH1E_HORSE Equus caballus 3 0.7426
Carbonic anhydrase 2 P00918 CAH2_HUMAN Homo sapiens 2 0.7425
Carbonic anhydrase 2 P00918 CAH2_HUMAN Homo sapiens 2 0.7425
Histone deacetylase-like amidohydrolase Q70I53 HDAH_ALCSD Alcaligenes sp.) 2 0.7423
Histone deacetylase-like amidohydrolase Q70I53 HDAH_ALCSD Alcaligenes sp.) 2 0.7423
Aldo-keto reductase family 1 member D1 P51857 AK1D1_HUMAN Homo sapiens 2 0.7421
Aldo-keto reductase family 1 member D1 P51857 AK1D1_HUMAN Homo sapiens 2 0.7421
Steroid Delta-isomerase P07445 SDIS_PSEPU Pseudomonas putida 2 0.7415
Steroid Delta-isomerase P07445 SDIS_PSEPU Pseudomonas putida 2 0.7415
Carbonic anhydrase 12 O43570 CAH12_HUMAN Homo sapiens 2 0.7405
Carbonic anhydrase 12 O43570 CAH12_HUMAN Homo sapiens 2 0.7405
Bromodomain-containing protein 4 O60885 BRD4_HUMAN Homo sapiens 2 0.7402
Bromodomain-containing protein 4 O60885 BRD4_HUMAN Homo sapiens 2 0.7402
3-phosphoinositide-dependent protein kinase 1 O15530 PDPK1_HUMAN Homo sapiens 3 0.7397
3-phosphoinositide-dependent protein kinase 1 O15530 PDPK1_HUMAN Homo sapiens 3 0.7397
Histone-lysine N-methyltransferase SETD7 Q8WTS6 SETD7_HUMAN Homo sapiens 3 0.7393
Histone-lysine N-methyltransferase SETD7 Q8WTS6 SETD7_HUMAN Homo sapiens 3 0.7393
Polyribonucleotide nucleotidyltransferase A7ZS61 PNP_ECO24 Escherichia coli O139:H28 3 0.7384
Polyribonucleotide nucleotidyltransferase A7ZS61 PNP_ECO24 Escherichia coli O139:H28 3 0.7384
Lanosterol 14-alpha-demethylase Q385E8 Q385E8_TRYB2 Trypanosoma brucei brucei 3 0.7383
Lanosterol 14-alpha-demethylase Q385E8 Q385E8_TRYB2 Trypanosoma brucei brucei 3 0.7383
Fatty acid-binding protein, liver P80226 FABPL_CHICK Gallus gallus 2 0.7380
Fatty acid-binding protein, liver P80226 FABPL_CHICK Gallus gallus 2 0.7380
Gastrotropin Q6IMW5 Q6IMW5_DANRE Danio rerio 2 0.7377
Gastrotropin Q6IMW5 Q6IMW5_DANRE Danio rerio 2 0.7377
Fibroblast growth factor receptor 1 P11362 FGFR1_HUMAN Homo sapiens 2 0.7375
Fibroblast growth factor receptor 1 P11362 FGFR1_HUMAN Homo sapiens 2 0.7375
Glutathione S-transferase P P09211 GSTP1_HUMAN Homo sapiens 2 0.7369
Glutathione S-transferase P P09211 GSTP1_HUMAN Homo sapiens 2 0.7369
Retinoic acid receptor RXR-alpha P19793 RXRA_HUMAN Homo sapiens 3 0.7359
Retinoic acid receptor RXR-alpha P19793 RXRA_HUMAN Homo sapiens 3 0.7359
Histone deacetylase 8 Q9BY41 HDAC8_HUMAN Homo sapiens 2 0.7355
Histone deacetylase 8 Q9BY41 HDAC8_HUMAN Homo sapiens 2 0.7355
Pentaerythritol tetranitrate reductase P71278 P71278_ENTCL Enterobacter cloacae 2 0.7350
Pentaerythritol tetranitrate reductase P71278 P71278_ENTCL Enterobacter cloacae 2 0.7350
Aldo-keto reductase family 1 member C2 P52895 AK1C2_HUMAN Homo sapiens 2 0.7346
Aldo-keto reductase family 1 member C2 P52895 AK1C2_HUMAN Homo sapiens 2 0.7346
Retinol-binding protein 1 P02696 RET1_RAT Rattus norvegicus 3 0.7327
Retinol-binding protein 1 P02696 RET1_RAT Rattus norvegicus 3 0.7327
Nuclear receptor ROR-alpha P35398 RORA_HUMAN Homo sapiens 3 0.7318
Nuclear receptor ROR-alpha P35398 RORA_HUMAN Homo sapiens 3 0.7318
Nuclear receptor subfamily 4immunitygroup A member 1 P22736 NR4A1_HUMAN Homo sapiens 3 0.7315
Nuclear receptor subfamily 4immunitygroup A member 1 P22736 NR4A1_HUMAN Homo sapiens 3 0.7315
Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase Q05603 COBT_SALTY Salmonella typhimurium 2 0.7308
Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase Q05603 COBT_SALTY Salmonella typhimurium 2 0.7308
Sulfide-quinone reductase B7JBP8 SQRD_ACIF2 Acidithiobacillus ferrooxidans) 4 0.7307
Sulfide-quinone reductase B7JBP8 SQRD_ACIF2 Acidithiobacillus ferrooxidans) 4 0.7307
Sulfotransferase 2A1 Q06520 ST2A1_HUMAN Homo sapiens 3 0.7306
Sulfotransferase 2A1 Q06520 ST2A1_HUMAN Homo sapiens 3 0.7306
Methylketone synthase I E0YCS2 E0YCS2_SOLHA Solanum habrochaites 2 0.7295
Methylketone synthase I E0YCS2 E0YCS2_SOLHA Solanum habrochaites 2 0.7295
Steroid C26-monooxygenase P9WPP1 CP125_MYCTU Mycobacterium tuberculosis 3 0.7282
Steroid C26-monooxygenase P9WPP1 CP125_MYCTU Mycobacterium tuberculosis 3 0.7282
Dicamba O-demethylase, oxygenase component Q5S3I3 DDMC_STEMA Stenotrophomonas maltophilia 3 0.7274
Dicamba O-demethylase, oxygenase component Q5S3I3 DDMC_STEMA Stenotrophomonas maltophilia 3 0.7274
Beta-1 adrenergic receptor P07700 ADRB1_MELGA Meleagris gallopavo 2 0.7262
Beta-1 adrenergic receptor P07700 ADRB1_MELGA Meleagris gallopavo 2 0.7262
Camphor 5-monooxygenase P00183 CPXA_PSEPU Pseudomonas putida 3 0.7260
Camphor 5-monooxygenase P00183 CPXA_PSEPU Pseudomonas putida 3 0.7260
Steroid Delta-isomerase P07445 SDIS_PSEPU Pseudomonas putida 2 0.7259
Steroid Delta-isomerase P07445 SDIS_PSEPU Pseudomonas putida 2 0.7259
Succinate dehydrogenase flavoprotein subunit P0AC41 SDHA_ECOLI Escherichia coli 3 0.7239
Succinate dehydrogenase flavoprotein subunit P0AC41 SDHA_ECOLI Escherichia coli 3 0.7239
Polyprotein Q80J95 Q80J95_9CALI Murine norovirus 1 2 0.7237
Polyprotein Q80J95 Q80J95_9CALI Murine norovirus 1 2 0.7237
Phospholipase A2, major isoenzyme P00592 PA21B_PIG Sus scrofa 3 0.7231
Phospholipase A2, major isoenzyme P00592 PA21B_PIG Sus scrofa 3 0.7231
Casein kinase II subunit alpha P68400 CSK21_HUMAN Homo sapiens 2 0.7223
Casein kinase II subunit alpha P68400 CSK21_HUMAN Homo sapiens 2 0.7223
ADP-ribosylation factor 1 P84080 ARF1_BOVIN Bos taurus 3 0.7222
ADP-ribosylation factor 1 P84080 ARF1_BOVIN Bos taurus 3 0.7222
Purine nucleoside phosphorylase DeoD-type O34925 DEOD_BACSU Bacillus subtilis 2 0.7218
Purine nucleoside phosphorylase DeoD-type O34925 DEOD_BACSU Bacillus subtilis 2 0.7218
High affinity 3',5'-cyclic-AMP phosphodiesterase 7A Q13946 PDE7A_HUMAN Homo sapiens 3 0.7217
High affinity 3',5'-cyclic-AMP phosphodiesterase 7A Q13946 PDE7A_HUMAN Homo sapiens 3 0.7217
Gag-Pol polyprotein P04585 POL_HV1H2 Human immunodeficiency virus type 1 group M subtype B 4 0.7216
Gag-Pol polyprotein P04585 POL_HV1H2 Human immunodeficiency virus type 1 group M subtype B 4 0.7216
Methylketone synthase I E0YCS2 E0YCS2_SOLHA Solanum habrochaites 3 0.7213
Methylketone synthase I E0YCS2 E0YCS2_SOLHA Solanum habrochaites 3 0.7213
Mitochondrial poly(A) polymerase F1NBW0 F1NBW0_CHICK Gallus gallus 2 0.7212
Mitochondrial poly(A) polymerase F1NBW0 F1NBW0_CHICK Gallus gallus 2 0.7212
17-beta-hydroxysteroid dehydrogenase type 1 P14061 DHB1_HUMAN Homo sapiens 2 0.7211
17-beta-hydroxysteroid dehydrogenase type 1 P14061 DHB1_HUMAN Homo sapiens 2 0.7211
Nuclear receptor ROR-gamma P51449 RORG_HUMAN Homo sapiens 2 0.7208
Nuclear receptor ROR-gamma P51449 RORG_HUMAN Homo sapiens 2 0.7208
Beta-2 adrenergic receptor P07550 ADRB2_HUMAN Homo sapiens 3 0.7208
Beta-2 adrenergic receptor P07550 ADRB2_HUMAN Homo sapiens 3 0.7208
Aldo-keto reductase family 1 member C1 Q04828 AK1C1_HUMAN Homo sapiens 2 0.7207
Aldo-keto reductase family 1 member C1 Q04828 AK1C1_HUMAN Homo sapiens 2 0.7207
Bile acid receptor Q62735 NR1H4_RAT Rattus norvegicus 4 0.7205
Bile acid receptor Q62735 NR1H4_RAT Rattus norvegicus 4 0.7205
Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase Q05603 COBT_SALTY Salmonella typhimurium 2 0.7202
Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase Q05603 COBT_SALTY Salmonella typhimurium 2 0.7202
LIM domain kinase 1 P53667 LIMK1_HUMAN Homo sapiens 2 0.7199
LIM domain kinase 1 P53667 LIMK1_HUMAN Homo sapiens 2 0.7199
Cartilage oligomeric matrix protein P35444 COMP_RAT Rattus norvegicus 3 0.7197
Cartilage oligomeric matrix protein P35444 COMP_RAT Rattus norvegicus 3 0.7197
Prolyl tripeptidyl peptidase Q7MUW6 PTP_PORGI Porphyromonas gingivalis 3 0.7195
Sulfotransferase 2A1 Q06520 ST2A1_HUMAN Homo sapiens 3 0.7195
Sulfotransferase 2A1 Q06520 ST2A1_HUMAN Homo sapiens 3 0.7195
Prolyl tripeptidyl peptidase Q7MUW6 PTP_PORGI Porphyromonas gingivalis 3 0.7195
D-aminoacyl-tRNA deacylase Q8IIS0 DTD_PLAF7 Plasmodium falciparum 3 0.7191
D-aminoacyl-tRNA deacylase Q8IIS0 DTD_PLAF7 Plasmodium falciparum 3 0.7191
Serine/threonine-protein kinase SKY1 Q03656 SKY1_YEAST Saccharomyces cerevisiae 2 0.7189
Serine/threonine-protein kinase SKY1 Q03656 SKY1_YEAST Saccharomyces cerevisiae 2 0.7189
Ribosyldihydronicotinamide dehydrogenase [quinone] P16083 NQO2_HUMAN Homo sapiens 3 0.7182
Ribosyldihydronicotinamide dehydrogenase [quinone] P16083 NQO2_HUMAN Homo sapiens 3 0.7182
Acetylcholinesterase P04058 ACES_TETCF Tetronarce californica 3 0.7179
Acetylcholinesterase P04058 ACES_TETCF Tetronarce californica 3 0.7179
Bromodomain-containing protein 2 P25440 BRD2_HUMAN Homo sapiens 2 0.7172
Bromodomain-containing protein 2 P25440 BRD2_HUMAN Homo sapiens 2 0.7172
Tetracycline repressor protein class D P0ACT4 TETR4_ECOLX Escherichia coli 2 0.7166
Tetracycline repressor protein class D P0ACT4 TETR4_ECOLX Escherichia coli 2 0.7166
Nuclear receptor coactivator 2 Q15596 NCOA2_HUMAN Homo sapiens 3 0.7166
Nuclear receptor coactivator 2 Q15596 NCOA2_HUMAN Homo sapiens 3 0.7166
Beta-1 adrenergic receptor P07700 ADRB1_MELGA Meleagris gallopavo 2 0.7163
Beta-1 adrenergic receptor P07700 ADRB1_MELGA Meleagris gallopavo 2 0.7163
17-beta-hydroxysteroid dehydrogenase type 1 P14061 DHB1_HUMAN Homo sapiens 3 0.7161
17-beta-hydroxysteroid dehydrogenase type 1 P14061 DHB1_HUMAN Homo sapiens 3 0.7161
Cartilage oligomeric matrix protein Q9R0G6 COMP_MOUSE Mus musculus 3 0.7154
Cartilage oligomeric matrix protein Q9R0G6 COMP_MOUSE Mus musculus 3 0.7154
3',5'-cyclic-AMP phosphodiesterase 4A P27815 PDE4A_HUMAN Homo sapiens 3 0.7151
3',5'-cyclic-AMP phosphodiesterase 4A P27815 PDE4A_HUMAN Homo sapiens 3 0.7151
Aldo-keto reductase family 1 member B1 P15121 ALDR_HUMAN Homo sapiens 3 0.7147
Aldo-keto reductase family 1 member B1 P15121 ALDR_HUMAN Homo sapiens 3 0.7147
Cyclin-dependent kinase 9 P50750 CDK9_HUMAN Homo sapiens 3 0.7146
Cyclin-dependent kinase 9 P50750 CDK9_HUMAN Homo sapiens 3 0.7146
Dihydropteroate synthase Q81VW8 Q81VW8_BACAN Bacillus anthracis 2 0.7145
Dihydropteroate synthase Q81VW8 Q81VW8_BACAN Bacillus anthracis 2 0.7145
Death-associated protein kinase 3 O43293 DAPK3_HUMAN Homo sapiens 2 0.7143
Death-associated protein kinase 3 O43293 DAPK3_HUMAN Homo sapiens 2 0.7143
Pancreatic alpha-amylase P04746 AMYP_HUMAN Homo sapiens 2 0.7138
Pancreatic alpha-amylase P04746 AMYP_HUMAN Homo sapiens 2 0.7138
Ribosyldihydronicotinamide dehydrogenase [quinone] P16083 NQO2_HUMAN Homo sapiens 3 0.7132
Ribosyldihydronicotinamide dehydrogenase [quinone] P16083 NQO2_HUMAN Homo sapiens 3 0.7132
Glycogen synthase kinase-3 beta P49841 GSK3B_HUMAN Homo sapiens 2 0.7125
Glycogen synthase kinase-3 beta P49841 GSK3B_HUMAN Homo sapiens 2 0.7125
N-alpha-acetyltransferase 50 Q9GZZ1 NAA50_HUMAN Homo sapiens 3 0.7120
N-alpha-acetyltransferase 50 Q9GZZ1 NAA50_HUMAN Homo sapiens 3 0.7120
Sphingosine 1-phosphate receptor 1 P21453 S1PR1_HUMAN Homo sapiens 3 0.7119
Sphingosine 1-phosphate receptor 1 P21453 S1PR1_HUMAN Homo sapiens 3 0.7119
NADPH-dependent oxidoreductase 2-alkenal reductase Q39172 AER_ARATH Arabidopsis thaliana 2 0.7118
NADPH-dependent oxidoreductase 2-alkenal reductase Q39172 AER_ARATH Arabidopsis thaliana 2 0.7118
Dihydrofolate reductase P9WNX1 DYR_MYCTU Mycobacterium tuberculosis 3 0.7114
Dihydrofolate reductase P9WNX1 DYR_MYCTU Mycobacterium tuberculosis 3 0.7114
Cytochrome P450 monooxygenase Q5YNS8 Q5YNS8_NOCFA Nocardia farcinica 2 0.7111
Cytochrome P450 monooxygenase Q5YNS8 Q5YNS8_NOCFA Nocardia farcinica 2 0.7111
Aldo-keto reductase family 1 member D1 P51857 AK1D1_HUMAN Homo sapiens 2 0.7103
Bifunctional epoxide hydrolase 2 P34913 HYES_HUMAN Homo sapiens 2 0.7103
Bifunctional epoxide hydrolase 2 P34913 HYES_HUMAN Homo sapiens 2 0.7103
Aldo-keto reductase family 1 member D1 P51857 AK1D1_HUMAN Homo sapiens 2 0.7103
Purine nucleoside phosphorylase P00491 PNPH_HUMAN Homo sapiens 3 0.7094
Purine nucleoside phosphorylase P00491 PNPH_HUMAN Homo sapiens 3 0.7094
Putative S-adenosyl-L-methionine-dependent methyltransferase ML2640 Q9CCZ4 Y2640_MYCLE Mycobacterium leprae 3 0.7084
Putative S-adenosyl-L-methionine-dependent methyltransferase ML2640 Q9CCZ4 Y2640_MYCLE Mycobacterium leprae 3 0.7084
Ribosyldihydronicotinamide dehydrogenase [quinone] P16083 NQO2_HUMAN Homo sapiens 2 0.7083
Ribosyldihydronicotinamide dehydrogenase [quinone] P16083 NQO2_HUMAN Homo sapiens 2 0.7083
Thymidine kinase P0DTH5 KITH_HHV11 Human herpesvirus 1 3 0.7082
Thymidine kinase P0DTH5 KITH_HHV11 Human herpesvirus 1 3 0.7082
Acetylcholine-binding protein P58154 ACHP_LYMST Lymnaea stagnalis 3 0.7082
Acetylcholine-binding protein P58154 ACHP_LYMST Lymnaea stagnalis 3 0.7082
Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase F6MZ55 F6MZ55_9FIRM Sporomusa ovata 2 0.7079
Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase F6MZ55 F6MZ55_9FIRM Sporomusa ovata 2 0.7079
Peptidyl-prolyl cis-trans isomerase FKBP1A P62942 FKB1A_HUMAN Homo sapiens 3 0.7075
Uncharacterized protein YML079W Q03629 YMH9_YEAST Saccharomyces cerevisiae 2 0.7075
Peptidyl-prolyl cis-trans isomerase FKBP1A P62942 FKB1A_HUMAN Homo sapiens 3 0.7075
Uncharacterized protein YML079W Q03629 YMH9_YEAST Saccharomyces cerevisiae 2 0.7075
Androgen receptor P10275 ANDR_HUMAN Homo sapiens 3 0.7069
Androgen receptor P10275 ANDR_HUMAN Homo sapiens 3 0.7069
DNA polymerase III subunit epsilon P03007 DPO3E_ECOLI Escherichia coli 3 0.7067
DNA polymerase III subunit epsilon P03007 DPO3E_ECOLI Escherichia coli 3 0.7067
Peptidyl-prolyl cis-trans isomerase FKBP1A P62942 FKB1A_HUMAN Homo sapiens 3 0.7061
Peptidyl-prolyl cis-trans isomerase FKBP1A P62942 FKB1A_HUMAN Homo sapiens 3 0.7061
Bifunctional dihydrofolate reductase-thymidylate synthase Q27783 DRTS_TRYBB Trypanosoma brucei brucei 3 0.7060
Bifunctional dihydrofolate reductase-thymidylate synthase Q27783 DRTS_TRYBB Trypanosoma brucei brucei 3 0.7060
Type IV / VI secretion system DotU domain-containing protein Q9KN50 Q9KN50_VIBCH Vibrio cholerae serotype O1 2 0.7052
Type IV / VI secretion system DotU domain-containing protein Q9KN50 Q9KN50_VIBCH Vibrio cholerae serotype O1 2 0.7052
Retinaldehyde-binding protein 1 P12271 RLBP1_HUMAN Homo sapiens 3 0.7050
Retinaldehyde-binding protein 1 P12271 RLBP1_HUMAN Homo sapiens 3 0.7050
3',5'-cyclic-AMP phosphodiesterase 4D Q08499 PDE4D_HUMAN Homo sapiens 2 0.7042
3',5'-cyclic-AMP phosphodiesterase 4D Q08499 PDE4D_HUMAN Homo sapiens 2 0.7042
Peroxisome proliferator-activated receptor alpha Q07869 PPARA_HUMAN Homo sapiens 3 0.7032
Peroxisome proliferator-activated receptor alpha Q07869 PPARA_HUMAN Homo sapiens 3 0.7032
Protocatechuate 3,4-dioxygenase beta chain P00437 PCXB_PSEPU Pseudomonas putida 2 0.7031
Protocatechuate 3,4-dioxygenase beta chain P00437 PCXB_PSEPU Pseudomonas putida 2 0.7031
Histone deacetylase 8 Q9BY41 HDAC8_HUMAN Homo sapiens 2 0.7026
Androgen receptor P10275 ANDR_HUMAN Homo sapiens 3 0.7026
Histone deacetylase 8 Q9BY41 HDAC8_HUMAN Homo sapiens 2 0.7026
Androgen receptor P10275 ANDR_HUMAN Homo sapiens 3 0.7026
2,7-dihydroxy-5-methyl-1-naphthoate 7-O-methyltransferase Q84HC8 NCSB1_STRCZ Streptomyces carzinostaticus 3 0.7021
2,7-dihydroxy-5-methyl-1-naphthoate 7-O-methyltransferase Q84HC8 NCSB1_STRCZ Streptomyces carzinostaticus 3 0.7021
Tetracycline repressor protein class D P0ACT4 TETR4_ECOLX Escherichia coli 3 0.7020
Tetracycline repressor protein class D P0ACT4 TETR4_ECOLX Escherichia coli 3 0.7020
Protein BRASSINOSTEROID INSENSITIVE 1 O22476 BRI1_ARATH Arabidopsis thaliana 3 0.7013
Protein BRASSINOSTEROID INSENSITIVE 1 O22476 BRI1_ARATH Arabidopsis thaliana 3 0.7013
Sphingosine 1-phosphate receptor 1 P21453 S1PR1_HUMAN Homo sapiens 3 0.7010
Sphingosine 1-phosphate receptor 1 P21453 S1PR1_HUMAN Homo sapiens 3 0.7010
Acetolactate synthase, chloroplastic P17597 ILVB_ARATH Arabidopsis thaliana 2 0.7009
Acetolactate synthase, chloroplastic P17597 ILVB_ARATH Arabidopsis thaliana 2 0.7009
Steroid 17-alpha-hydroxylase/17,20 lyase P05093 CP17A_HUMAN Homo sapiens 3 0.7009
Steroid 17-alpha-hydroxylase/17,20 lyase P05093 CP17A_HUMAN Homo sapiens 3 0.7009

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