1,4,6-trihydroxy-3-methoxy-2-(3-methyl-2-butenyl)-5-(1,1-dimethyl-prop-2-enyl)xanthone - Compound Card

1,4,6-trihydroxy-3-methoxy-2-(3-methyl-2-butenyl)-5-(1,1-dimethyl-prop-2-enyl)xanthone

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1,4,6-trihydroxy-3-methoxy-2-(3-methyl-2-butenyl)-5-(1,1-dimethyl-prop-2-enyl)xanthone

Structure
Zoomed Structure
  • Family: Plantae - Clusiaceae-Guttiferae
  • Kingdom: Plantae
  • Class: Xanthone
Canonical Smiles C=CC(c1c(O)ccc2c1oc1c(O)c(OC)c(c(c1c2=O)O)CC=C(C)C)(C)C
InChI InChI=1S/C24H26O6/c1-7-24(4,5)17-15(25)11-10-13-18(26)16-19(27)14(9-8-12(2)3)22(29-6)20(28)23(16)30-21(13)17/h7-8,10-11,25,27-28H,1,9H2,2-6H3
InChIKey RHYDKWXOGNKPQK-UHFFFAOYSA-N
Formula C24H26O6
HBA 6
HBD 3
MW 410.47
Rotatable Bonds 5
TPSA 100.13
LogP 5.04
Number Rings 3
Number Aromatic Rings 3
Heavy Atom Count 30
Formal Charge 0
Fraction CSP3 0.29
Exact Mass 410.17
Number of Lipinski Rule Violations 1
# Species Family Kingdom NCBI Taxonomy ID
1 Garcinia edulis Clusiaceae-Guttiferae Plantae 58227

Showing of synonyms

  • Magadula JJ. (2010). A bioactive isoprenylated xanthone and other constituents of Garcinia edulis. Fitoterapia,2010,81(5),420-423. [View] [PubMed]
Pubchem: 46894020
Nmrshiftdb2: 70078310
CPRiL: 105930
Structure

SMILES: c1cccc(c12)oc3c(c2=O)cccc3

Level: 0

Mol. Weight: 410.47 g/mol

Anti-hiv-1 protease
Cytotoxic

Absorption

Caco-2 (logPapp)
-5.34
Human Oral Bioavailability 20%
Bioavailable
Human Intestinal Absorption
Absorbed
Madin-Darby Canine Kidney
-4.91
Human Oral Bioavailability 50%
Bioavailable
P-Glycoprotein Inhibitor
Inhibitor
P-Glycoprotein Substrate
Non-Substrate
Skin Permeability
-1.09

Distribution

Blood-Brain Barrier (CNS)
-
Blood-Brain Barrier
Non-Penetrable
Fraction Unbound (Human)
1.21
Plasma Protein Binding
58.01
Steady State Volume of Distribution
-

Metabolism

Breast Cancer Resistance Protein
Inhibitor
CYP 1A2 Inhibitor
Inhibitor
CYP 1A2 Substrate
Non-Substrate
CYP 2C19 Inhibitor
Inhibitor
CYP 2C19 Substrate
Non-Substrate
CYP 2C9 Inhibitor
Inhibitor
CYP 2C9 Substrate
Substrate
CYP 2D6 Inhibitor
Inhibitor
CYP 2D6 Substrate
Non-Substrate
CYP 3A4 Inhibitor
Inhibitor
CYP 3A4 Substrate
Non-Substrate
OATP1B1
Inhibitor
OATP1B3
Non-Inhibitor

Excretion

Clearance
4.66
Organic Cation Transporter 2
Inhibitor
Half-Life of Drug
-

Toxicity

AMES Mutagenesis
Toxic
Avian
Safe
Bee
Toxic
Bioconcentration Factor
0.92
Biodegradation
Safe
Carcinogenesis
Safe
Crustacean
Toxic
Liver Injury I (DILI)
Toxic
Eye Corrosion
Safe
Eye Irritation
Safe
Maximum Tolerated Dose
0.5
Liver Injury II
Toxic
hERG Blockers
Safe
Daphnia Maga
6.55
Micronucleos
Toxic
NR-AhR
Toxic
NR-AR
Safe
NR-AR-LBD
Safe
NR-Aromatase
Safe
NR-ER
Safe
NR-ER-LBD
Safe
NR-GR
Safe
NR-PPAR-gamma
Safe
NR-TR
Safe
T. Pyriformis
-12.05
Rat (Acute)
2.33
Rat (Chronic Oral)
2.82
Fathead Minnow
5.35
Respiratory Disease
Toxic
Skin Sensitisation
Safe
SR-ARE
Toxic
SR-ATAD5
Safe
SR-HSE
Safe
SR-MMP
Toxic
SR-p53
Safe

General Properties

Boiling Point
485.85
Hydration Free Energy
-6.99
Log(D) at pH=7.4
3.3
Log(P)
5.79
Log S
-6.3
Log(Vapor Pressure)
-8.53
Melting Point
164.54
pKa Acid
7.87
pKa Basic
6.2
Protein Name UniProt ID Entry Name Species #Pharmacophore Points Probability (0.7 ≤ Tversky Score ≤ 1.0)
Riboflavin synthase P0AFU8 RISA_ECOLI Escherichia coli 4 0.9074
Riboflavin synthase P0AFU8 RISA_ECOLI Escherichia coli 4 0.9074
Serine/threonine-protein kinase SKY1 Q03656 SKY1_YEAST Saccharomyces cerevisiae 3 0.9045
Serine/threonine-protein kinase SKY1 Q03656 SKY1_YEAST Saccharomyces cerevisiae 3 0.9045
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform O02697 PK3CG_PIG Sus scrofa 3 0.8991
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform O02697 PK3CG_PIG Sus scrofa 3 0.8991
Capsid protein Q9WBP8 Q9WBP8_9VIRU Adeno-associated virus - 1 3 0.8943
Capsid protein Q9WBP8 Q9WBP8_9VIRU Adeno-associated virus - 1 3 0.8943
Carbonic anhydrase 2 P00918 CAH2_HUMAN Homo sapiens 3 0.8802
Carbonic anhydrase 2 P00918 CAH2_HUMAN Homo sapiens 3 0.8802
3',5'-cyclic-AMP phosphodiesterase 4D Q08499 PDE4D_HUMAN Homo sapiens 3 0.8715
3',5'-cyclic-AMP phosphodiesterase 4D Q08499 PDE4D_HUMAN Homo sapiens 3 0.8715
Fibroblast growth factor receptor 1 P11362 FGFR1_HUMAN Homo sapiens 3 0.8624
Fibroblast growth factor receptor 1 P11362 FGFR1_HUMAN Homo sapiens 3 0.8624
Epidermal growth factor receptor P00533 EGFR_HUMAN Homo sapiens 3 0.8573
Epidermal growth factor receptor P00533 EGFR_HUMAN Homo sapiens 3 0.8573
Fibroblast growth factor receptor 2 P21802 FGFR2_HUMAN Homo sapiens 3 0.8471
Fibroblast growth factor receptor 2 P21802 FGFR2_HUMAN Homo sapiens 3 0.8471
Protein ppBat Q8A8A4 Q8A8A4_BACTN Bacteroides thetaiotaomicron VPI-5482 3 0.8460
Protein ppBat Q8A8A4 Q8A8A4_BACTN Bacteroides thetaiotaomicron VPI-5482 3 0.8460
Fibroblast growth factor receptor 2 P21802 FGFR2_HUMAN Homo sapiens 3 0.8430
Fibroblast growth factor receptor 2 P21802 FGFR2_HUMAN Homo sapiens 3 0.8430
Homoserine dehydrogenase P31116 DHOM_YEAST Saccharomyces cerevisiae 4 0.8324
Homoserine dehydrogenase P31116 DHOM_YEAST Saccharomyces cerevisiae 4 0.8324
LIM domain kinase 1 P53667 LIMK1_HUMAN Homo sapiens 3 0.8318
LIM domain kinase 1 P53667 LIMK1_HUMAN Homo sapiens 3 0.8318
TetR family transcriptional regulator Q58L87 Q58L87_MYCSM Mycolicibacterium smegmatis 3 0.8290
TetR family transcriptional regulator Q58L87 Q58L87_MYCSM Mycolicibacterium smegmatis 3 0.8290
MAP kinase-activated protein kinase 2 P49137 MAPK2_HUMAN Homo sapiens 3 0.8177
MAP kinase-activated protein kinase 2 P49137 MAPK2_HUMAN Homo sapiens 3 0.8177
Ribosyldihydronicotinamide dehydrogenase [quinone] P16083 NQO2_HUMAN Homo sapiens 3 0.8113
Ribosyldihydronicotinamide dehydrogenase [quinone] P16083 NQO2_HUMAN Homo sapiens 3 0.8113
Pheromone-binding protein ASP1 Q9U9J6 Q9U9J6_APIME Apis mellifera 3 0.8108
Pheromone-binding protein ASP1 Q9U9J6 Q9U9J6_APIME Apis mellifera 3 0.8108
Ribosyldihydronicotinamide dehydrogenase [quinone] P16083 NQO2_HUMAN Homo sapiens 3 0.8015
Ribosyldihydronicotinamide dehydrogenase [quinone] P16083 NQO2_HUMAN Homo sapiens 3 0.8015
prolyl oligopeptidase Q9X6R4 Q9X6R4_AERCA Aeromonas caviae 3 0.8013
prolyl oligopeptidase Q9X6R4 Q9X6R4_AERCA Aeromonas caviae 3 0.8013
Prolyl tripeptidyl peptidase Q7MUW6 PTP_PORGI Porphyromonas gingivalis 3 0.7991
Prolyl tripeptidyl peptidase Q7MUW6 PTP_PORGI Porphyromonas gingivalis 3 0.7991
Nitric oxide synthase oxygenase O34453 NOSO_BACSU Bacillus subtilis 4 0.7983
Nitric oxide synthase oxygenase O34453 NOSO_BACSU Bacillus subtilis 4 0.7983
ATP-dependent molecular chaperone HSP82 P02829 HSP82_YEAST Saccharomyces cerevisiae 3 0.7982
ATP-dependent molecular chaperone HSP82 P02829 HSP82_YEAST Saccharomyces cerevisiae 3 0.7982
Lactoylglutathione lyase Q9CPU0 LGUL_MOUSE Mus musculus 2 0.7953
Lactoylglutathione lyase Q9CPU0 LGUL_MOUSE Mus musculus 2 0.7953
Nuclear receptor ROR-gamma P51449 RORG_HUMAN Homo sapiens 3 0.7947
Nuclear receptor ROR-gamma P51449 RORG_HUMAN Homo sapiens 3 0.7947
Acetylcholinesterase P04058 ACES_TETCF Tetronarce californica 3 0.7935
Acetylcholinesterase P04058 ACES_TETCF Tetronarce californica 3 0.7935
Ribosyldihydronicotinamide dehydrogenase [quinone] P16083 NQO2_HUMAN Homo sapiens 3 0.7881
Ribosyldihydronicotinamide dehydrogenase [quinone] P16083 NQO2_HUMAN Homo sapiens 3 0.7881
3',5'-cyclic-AMP phosphodiesterase 4D Q08499 PDE4D_HUMAN Homo sapiens 3 0.7880
3',5'-cyclic-AMP phosphodiesterase 4D Q08499 PDE4D_HUMAN Homo sapiens 3 0.7880
Basic phospholipase A2 VRV-PL-VIIIa P59071 PA2B8_DABRR Daboia russelii 3 0.7878
Basic phospholipase A2 VRV-PL-VIIIa P59071 PA2B8_DABRR Daboia russelii 3 0.7878
Transcriptional regulator, PadR-like family A2RI36 A2RI36_LACLM Lactococcus lactis subsp. cremoris 2 0.7845
Transcriptional regulator, PadR-like family A2RI36 A2RI36_LACLM Lactococcus lactis subsp. cremoris 2 0.7845
Fatty acid-binding protein, liver P80226 FABPL_CHICK Gallus gallus 3 0.7829
Fatty acid-binding protein, liver P80226 FABPL_CHICK Gallus gallus 3 0.7829
2-phospho-L-lactate transferase Q8PVT6 COFD_METMA Methanosarcina mazei 3 0.7746
2-phospho-L-lactate transferase Q8PVT6 COFD_METMA Methanosarcina mazei 3 0.7746
High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A O76083 PDE9A_HUMAN Homo sapiens 4 0.7714
High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A O76083 PDE9A_HUMAN Homo sapiens 4 0.7714
Aldo-keto reductase family 1 member B1 P15121 ALDR_HUMAN Homo sapiens 2 0.7701
Aldo-keto reductase family 1 member B1 P15121 ALDR_HUMAN Homo sapiens 2 0.7701
HTH-type transcriptional repressor PurR P0ACP7 PURR_ECOLI Escherichia coli 4 0.7664
HTH-type transcriptional repressor PurR P0ACP7 PURR_ECOLI Escherichia coli 4 0.7664
Carbonic anhydrase 2 P00918 CAH2_HUMAN Homo sapiens 3 0.7634
Carbonic anhydrase 2 P00918 CAH2_HUMAN Homo sapiens 3 0.7634
4-diphosphocytidyl-2-C-methyl-D-erythritol kinase O67060 ISPE_AQUAE Aquifex aeolicus 3 0.7627
4-diphosphocytidyl-2-C-methyl-D-erythritol kinase O67060 ISPE_AQUAE Aquifex aeolicus 3 0.7627
Basic phospholipase A2 VRV-PL-VIIIa P59071 PA2B8_DABRR Daboia russelii 2 0.7617
Basic phospholipase A2 VRV-PL-VIIIa P59071 PA2B8_DABRR Daboia russelii 2 0.7617
CmeR Q7B8P6 Q7B8P6_CAMJU Campylobacter jejuni 2 0.7607
CmeR Q7B8P6 Q7B8P6_CAMJU Campylobacter jejuni 2 0.7607
Ribosyldihydronicotinamide dehydrogenase [quinone] P16083 NQO2_HUMAN Homo sapiens 3 0.7585
Ribosyldihydronicotinamide dehydrogenase [quinone] P16083 NQO2_HUMAN Homo sapiens 3 0.7585
Polyprotein Q80J95 Q80J95_9CALI Murine norovirus 1 3 0.7573
Polyprotein Q80J95 Q80J95_9CALI Murine norovirus 1 3 0.7573
3',5'-cyclic-AMP phosphodiesterase 4D Q08499 PDE4D_HUMAN Homo sapiens 3 0.7565
3',5'-cyclic-AMP phosphodiesterase 4D Q08499 PDE4D_HUMAN Homo sapiens 3 0.7565
Protein S100-A13 Q99584 S10AD_HUMAN Homo sapiens 3 0.7528
Protein S100-A13 Q99584 S10AD_HUMAN Homo sapiens 3 0.7528
High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A O76083 PDE9A_HUMAN Homo sapiens 3 0.7505
High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A O76083 PDE9A_HUMAN Homo sapiens 3 0.7505
Cyclin-dependent kinase 2 P24941 CDK2_HUMAN Homo sapiens 4 0.7505
Cyclin-dependent kinase 2 P24941 CDK2_HUMAN Homo sapiens 4 0.7505
Casein kinase II subunit alpha P68400 CSK21_HUMAN Homo sapiens 3 0.7500
Casein kinase II subunit alpha P68400 CSK21_HUMAN Homo sapiens 3 0.7500
Lactotransferrin P24627 TRFL_BOVIN Bos taurus 2 0.7463
Lactotransferrin P24627 TRFL_BOVIN Bos taurus 2 0.7463
Basic phospholipase A2 VRV-PL-VIIIa P59071 PA2B8_DABRR Daboia russelii 2 0.7459
Basic phospholipase A2 VRV-PL-VIIIa P59071 PA2B8_DABRR Daboia russelii 2 0.7459
Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase Q9TQS6 DHDH_MACFA Macaca fascicularis 3 0.7450
Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase Q9TQS6 DHDH_MACFA Macaca fascicularis 3 0.7450
Polyribonucleotide nucleotidyltransferase A7ZS61 PNP_ECO24 Escherichia coli O139:H28 3 0.7448
Polyribonucleotide nucleotidyltransferase A7ZS61 PNP_ECO24 Escherichia coli O139:H28 3 0.7448
Tyrosine-protein kinase Lck P06239 LCK_HUMAN Homo sapiens 3 0.7443
Tyrosine-protein kinase Lck P06239 LCK_HUMAN Homo sapiens 3 0.7443
Ribosyldihydronicotinamide dehydrogenase [quinone] P16083 NQO2_HUMAN Homo sapiens 3 0.7436
Ribosyldihydronicotinamide dehydrogenase [quinone] P16083 NQO2_HUMAN Homo sapiens 3 0.7436
S-adenosylmethionine decarboxylase proenzyme P17707 DCAM_HUMAN Homo sapiens 3 0.7417
S-adenosylmethionine decarboxylase proenzyme P17707 DCAM_HUMAN Homo sapiens 3 0.7417
EbrA repressor Q79SH7 Q79SH7_STRLI Streptomyces lividans 3 0.7411
EbrA repressor Q79SH7 Q79SH7_STRLI Streptomyces lividans 3 0.7411
Basic phospholipase A2 VRV-PL-VIIIa P59071 PA2B8_DABRR Daboia russelii 4 0.7403
Basic phospholipase A2 VRV-PL-VIIIa P59071 PA2B8_DABRR Daboia russelii 4 0.7403
CmeR Q7B8P6 Q7B8P6_CAMJU Campylobacter jejuni 2 0.7396
CmeR Q7B8P6 Q7B8P6_CAMJU Campylobacter jejuni 2 0.7396
High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A O76083 PDE9A_HUMAN Homo sapiens 3 0.7370
High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A O76083 PDE9A_HUMAN Homo sapiens 3 0.7370
Cyclin-dependent kinase 9 P50750 CDK9_HUMAN Homo sapiens 3 0.7361
Cyclin-dependent kinase 9 P50750 CDK9_HUMAN Homo sapiens 3 0.7361
HTH-type transcriptional repressor PurR P0ACP7 PURR_ECOLI Escherichia coli 3 0.7336
HTH-type transcriptional repressor PurR P0ACP7 PURR_ECOLI Escherichia coli 3 0.7336
Cyclin-dependent kinase 9 P50750 CDK9_HUMAN Homo sapiens 3 0.7302
Cyclin-dependent kinase 9 P50750 CDK9_HUMAN Homo sapiens 3 0.7302
Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplastic Q43088 RBCMT_PEA Pisum sativum 3 0.7288
Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplastic Q43088 RBCMT_PEA Pisum sativum 3 0.7288
Soluble acetylcholine receptor Q8WSF8 Q8WSF8_APLCA Aplysia californica 3 0.7287
Soluble acetylcholine receptor Q8WSF8 Q8WSF8_APLCA Aplysia californica 3 0.7287
Serine/threonine-protein kinase pim-1 P11309 PIM1_HUMAN Homo sapiens 3 0.7279
Serine/threonine-protein kinase pim-1 P11309 PIM1_HUMAN Homo sapiens 3 0.7279
Sepiapterin reductase Q64105 SPRE_MOUSE Mus musculus 3 0.7278
Sepiapterin reductase Q64105 SPRE_MOUSE Mus musculus 3 0.7278
Phosphatidylinositol 5-phosphate 4-kinase type-2 beta P78356 PI42B_HUMAN Homo sapiens 3 0.7266
Phosphatidylinositol 5-phosphate 4-kinase type-2 beta P78356 PI42B_HUMAN Homo sapiens 3 0.7266
Cyclin-dependent kinase 2 P24941 CDK2_HUMAN Homo sapiens 3 0.7262
Cyclin-dependent kinase 2 P24941 CDK2_HUMAN Homo sapiens 3 0.7262
Serine/threonine-protein kinase pim-1 P11309 PIM1_HUMAN Homo sapiens 3 0.7258
Serine/threonine-protein kinase pim-1 P11309 PIM1_HUMAN Homo sapiens 3 0.7258
Putative protease I Q8A8A4 Q8A8A4_BACTN Bacteroides thetaiotaomicron 2 0.7250
Putative protease I Q8A8A4 Q8A8A4_BACTN Bacteroides thetaiotaomicron 2 0.7250
Casein kinase II subunit alpha P68400 CSK21_HUMAN Homo sapiens 3 0.7248
Casein kinase II subunit alpha P68400 CSK21_HUMAN Homo sapiens 3 0.7248
Focal adhesion kinase 1 Q05397 FAK1_HUMAN Homo sapiens 3 0.7243
Focal adhesion kinase 1 Q05397 FAK1_HUMAN Homo sapiens 3 0.7243
Pteridine reductase, putative Q581W1 Q581W1_TRYB2 Trypanosoma brucei brucei 3 0.7232
Pteridine reductase, putative Q581W1 Q581W1_TRYB2 Trypanosoma brucei brucei 3 0.7232
Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase Q05603 COBT_SALTY Salmonella typhimurium 2 0.7229
Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase Q05603 COBT_SALTY Salmonella typhimurium 2 0.7229
Nitroreductase domain-containing protein Q8DW21 Q8DW21_STRMU Streptococcus mutans serotype c 3 0.7227
Nitroreductase domain-containing protein Q8DW21 Q8DW21_STRMU Streptococcus mutans serotype c 3 0.7227
Lactotransferrin P24627 TRFL_BOVIN Bos taurus 2 0.7202
Lactotransferrin P24627 TRFL_BOVIN Bos taurus 2 0.7202
Heat shock protein HSP 90-alpha P07900 HS90A_HUMAN Homo sapiens 3 0.7199
Heat shock protein HSP 90-alpha P07900 HS90A_HUMAN Homo sapiens 3 0.7199
Nucleoside diphosphate kinase A 2 P52175 NDKA2_BOVIN Bos taurus 3 0.7190
Nucleoside diphosphate kinase A 2 P52175 NDKA2_BOVIN Bos taurus 3 0.7190
Soluble cytochrome b562 P0ABE7 C562_ECOLX Escherichia coli 2 0.7186
Soluble cytochrome b562 P0ABE7 C562_ECOLX Escherichia coli 2 0.7186
HTH-type transcriptional repressor PurR P0ACP7 PURR_ECOLI Escherichia coli 3 0.7180
HTH-type transcriptional repressor PurR P0ACP7 PURR_ECOLI Escherichia coli 3 0.7180
Epidermal growth factor receptor P00533 EGFR_HUMAN Homo sapiens 3 0.7167
Epidermal growth factor receptor P00533 EGFR_HUMAN Homo sapiens 3 0.7167
Aldo-keto reductase family 1 member D1 P51857 AK1D1_HUMAN Homo sapiens 2 0.7166
Aldo-keto reductase family 1 member D1 P51857 AK1D1_HUMAN Homo sapiens 2 0.7166
GCN5-related N-acetyltransferase B1YEL6 B1YEL6_EXIS2 Exiguobacterium sibiricum 3 0.7161
GCN5-related N-acetyltransferase B1YEL6 B1YEL6_EXIS2 Exiguobacterium sibiricum 3 0.7161
Cyclin-dependent kinase 6 Q00534 CDK6_HUMAN Homo sapiens 3 0.7154
Cyclin-dependent kinase 6 Q00534 CDK6_HUMAN Homo sapiens 3 0.7154
GCN5-related N-acetyltransferase B1YEL6 B1YEL6_EXIS2 Exiguobacterium sibiricum 3 0.7121
GCN5-related N-acetyltransferase B1YEL6 B1YEL6_EXIS2 Exiguobacterium sibiricum 3 0.7121
Lethal(3)malignant brain tumor-like protein 1 Q9Y468 LMBL1_HUMAN Homo sapiens 3 0.7105
Lethal(3)malignant brain tumor-like protein 1 Q9Y468 LMBL1_HUMAN Homo sapiens 3 0.7105
Genome polyprotein P26663 POLG_HCVBK Hepatitis C virus genotype 1b 4 0.7098
Genome polyprotein P26663 POLG_HCVBK Hepatitis C virus genotype 1b 4 0.7098
Beta-secretase 1 P56817 BACE1_HUMAN Homo sapiens 2 0.7096
Beta-secretase 1 P56817 BACE1_HUMAN Homo sapiens 2 0.7096
Phosphodiesterase Q53I60 Q53I60_TRYCR Trypanosoma cruzi 3 0.7062
Phosphodiesterase Q53I60 Q53I60_TRYCR Trypanosoma cruzi 3 0.7062
Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplastic Q43088 RBCMT_PEA Pisum sativum 3 0.7005
Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplastic Q43088 RBCMT_PEA Pisum sativum 3 0.7005
Nuclear receptor subfamily 4immunitygroup A member 1 P22736 NR4A1_HUMAN Homo sapiens 3 0.7002
Nuclear receptor subfamily 4immunitygroup A member 1 P22736 NR4A1_HUMAN Homo sapiens 3 0.7002

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