5-[(5-acetoxymethyl-2-thienyl)-2-(but-3-en-1-ynyl)]-thiophene - Compound Card

5-[(5-acetoxymethyl-2-thienyl)-2-(but-3-en-1-ynyl)]-thiophene

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5-[(5-acetoxymethyl-2-thienyl)-2-(but-3-en-1-ynyl)]-thiophene

Structure
Zoomed Structure
  • Family: Plantae - Asteraceae
  • Kingdom: Plantae
  • Class: Monothiophene
Canonical Smiles C=CC#Cc1ccc(s1)c1ccc(s1)COC(=O)C
InChI InChI=1S/C15H12O2S2/c1-3-4-5-12-6-8-14(18-12)15-9-7-13(19-15)10-17-11(2)16/h3,6-9H,1,10H2,2H3
InChIKey SYEWLUATUDURPR-UHFFFAOYSA-N
Formula C15H12O2S2
HBA 4
HBD 0
MW 288.39
Rotatable Bonds 3
TPSA 26.3
LogP 4.08
Number Rings 2
Number Aromatic Rings 2
Heavy Atom Count 19
Formal Charge 0
Fraction CSP3 0.13
Exact Mass 288.03
Number of Lipinski Rule Violations 0
# Species Family Kingdom NCBI Taxonomy ID
1 Escinops ellenbeckii Asteraceae Plantae —

Showing of synonyms

  • Hymete A, Rohloff J, et al. (2005). Acetylenic thiophenes from the roots of Escinops ellenbeckii from Ethiopia. Natural Product Research,2005,19(8),755-761. [View] [PubMed]
Pubchem: 5315563
Chebi: 191930
Nmrshiftdb2: 60059037

No compound-protein relationship available.

Structure

SMILES: s1cccc1-c2cccs2

Level: 1

Mol. Weight: 288.39 g/mol

Structure

SMILES: c1ccsc1

Level: 0

Mol. Weight: 288.39 g/mol

No bioactivities available.

Absorption

Caco-2 (logPapp)
-4.62
Human Oral Bioavailability 20%
Bioavailable
Human Intestinal Absorption
Absorbed
Madin-Darby Canine Kidney
-4.03
Human Oral Bioavailability 50%
Bioavailable
P-Glycoprotein Inhibitor
Non-Inhibitor
P-Glycoprotein Substrate
Non-Substrate
Skin Permeability
-1.86

Distribution

Blood-Brain Barrier (CNS)
-
Blood-Brain Barrier
Penetrable
Fraction Unbound (Human)
1.76
Plasma Protein Binding
76.75
Steady State Volume of Distribution
-

Metabolism

Breast Cancer Resistance Protein
Inhibitor
CYP 1A2 Inhibitor
Inhibitor
CYP 1A2 Substrate
Non-Substrate
CYP 2C19 Inhibitor
Inhibitor
CYP 2C19 Substrate
Substrate
CYP 2C9 Inhibitor
Inhibitor
CYP 2C9 Substrate
Substrate
CYP 2D6 Inhibitor
Non-Inhibitor
CYP 2D6 Substrate
Non-Substrate
CYP 3A4 Inhibitor
Inhibitor
CYP 3A4 Substrate
Substrate
OATP1B1
Inhibitor
OATP1B3
Non-Inhibitor

Excretion

Clearance
2.69
Organic Cation Transporter 2
Non-Inhibitor
Half-Life of Drug
-

Toxicity

AMES Mutagenesis
Toxic
Avian
Safe
Bee
Safe
Bioconcentration Factor
2.62
Biodegradation
Safe
Carcinogenesis
Toxic
Crustacean
Toxic
Liver Injury I (DILI)
Toxic
Eye Corrosion
Safe
Eye Irritation
Toxic
Maximum Tolerated Dose
1.02
Liver Injury II
Toxic
hERG Blockers
Safe
Daphnia Maga
5.01
Micronucleos
Toxic
NR-AhR
Toxic
NR-AR
Safe
NR-AR-LBD
Safe
NR-Aromatase
Safe
NR-ER
Toxic
NR-ER-LBD
Safe
NR-GR
Toxic
NR-PPAR-gamma
Safe
NR-TR
Toxic
T. Pyriformis
5.39
Rat (Acute)
2.0
Rat (Chronic Oral)
1.14
Fathead Minnow
4.98
Respiratory Disease
Toxic
Skin Sensitisation
Toxic
SR-ARE
Toxic
SR-ATAD5
Toxic
SR-HSE
Safe
SR-MMP
Safe
SR-p53
Safe

General Properties

Boiling Point
362.52
Hydration Free Energy
-5.74
Log(D) at pH=7.4
4.26
Log(P)
4.77
Log S
-4.51
Log(Vapor Pressure)
-5.4
Melting Point
47.05
pKa Acid
8.59
pKa Basic
-0.3
Protein Name UniProt ID Entry Name Species #Pharmacophore Points Probability (0.7 ≤ Tversky Score ≤ 1.0)
Corticosteroid-binding globulin P08185 CBG_HUMAN Homo sapiens 3 0.9910
Corticosteroid-binding globulin P08185 CBG_HUMAN Homo sapiens 3 0.9910
Epidermal growth factor receptor P00533 EGFR_HUMAN Homo sapiens 3 0.9810
Epidermal growth factor receptor P00533 EGFR_HUMAN Homo sapiens 3 0.9810
Aldo-keto reductase family 1 member D1 P51857 AK1D1_HUMAN Homo sapiens 3 0.9790
Aldo-keto reductase family 1 member D1 P51857 AK1D1_HUMAN Homo sapiens 3 0.9790
Aldo-keto reductase family 1 member C2 P52895 AK1C2_HUMAN Homo sapiens 3 0.9788
Aldo-keto reductase family 1 member C2 P52895 AK1C2_HUMAN Homo sapiens 3 0.9788
Bromodomain adjacent to zinc finger domain protein 2B Q9UIF8 BAZ2B_HUMAN Homo sapiens 3 0.9770
Bromodomain adjacent to zinc finger domain protein 2B Q9UIF8 BAZ2B_HUMAN Homo sapiens 3 0.9770
Mineralocorticoid receptor P08235 MCR_HUMAN Homo sapiens 3 0.9733
Mineralocorticoid receptor P08235 MCR_HUMAN Homo sapiens 3 0.9733
Prostaglandin G/H synthase 1 P05979 PGH1_SHEEP Ovis aries 3 0.9730
Prostaglandin G/H synthase 1 P05979 PGH1_SHEEP Ovis aries 3 0.9730
Epidermal growth factor receptor P00533 EGFR_HUMAN Homo sapiens 3 0.9667
Epidermal growth factor receptor P00533 EGFR_HUMAN Homo sapiens 3 0.9667
Epidermal growth factor receptor P00533 EGFR_HUMAN Homo sapiens 3 0.9641
Epidermal growth factor receptor P00533 EGFR_HUMAN Homo sapiens 3 0.9641
Aldo-keto reductase family 1 member D1 P51857 AK1D1_HUMAN Homo sapiens 3 0.9636
Aldo-keto reductase family 1 member D1 P51857 AK1D1_HUMAN Homo sapiens 3 0.9636
Retinoic acid receptor RXR-alpha P19793 RXRA_HUMAN Homo sapiens 3 0.9627
Retinoic acid receptor RXR-alpha P19793 RXRA_HUMAN Homo sapiens 3 0.9627
Aldo-keto reductase family 1 member C2 P52895 AK1C2_HUMAN Homo sapiens 3 0.9602
Aldo-keto reductase family 1 member C2 P52895 AK1C2_HUMAN Homo sapiens 3 0.9602
Progesterone receptor P06401 PRGR_HUMAN Homo sapiens 3 0.9571
Progesterone receptor P06401 PRGR_HUMAN Homo sapiens 3 0.9571
Mineralocorticoid receptor P08235 MCR_HUMAN Homo sapiens 3 0.9566
Mineralocorticoid receptor P08235 MCR_HUMAN Homo sapiens 3 0.9566
Aldo-keto reductase family 1 member D1 P51857 AK1D1_HUMAN Homo sapiens 3 0.9527
Aldo-keto reductase family 1 member D1 P51857 AK1D1_HUMAN Homo sapiens 3 0.9527
Mineralocorticoid receptor P08235 MCR_HUMAN Homo sapiens 3 0.9523
Mineralocorticoid receptor P08235 MCR_HUMAN Homo sapiens 3 0.9523
Progesterone receptor P06401 PRGR_HUMAN Homo sapiens 3 0.9510
Progesterone receptor P06401 PRGR_HUMAN Homo sapiens 3 0.9510
NPC intracellular cholesterol transporter 1 O15118 NPC1_HUMAN Homo sapiens 3 0.9506
NPC intracellular cholesterol transporter 1 O15118 NPC1_HUMAN Homo sapiens 3 0.9506
Aldo-keto reductase family 1 member C2 P52895 AK1C2_HUMAN Homo sapiens 3 0.9475
Aldo-keto reductase family 1 member C2 P52895 AK1C2_HUMAN Homo sapiens 3 0.9475
Na(+):neurotransmitter symporter (Snf family) O67854 O67854_AQUAE Aquifex aeolicus 3 0.9448
Na(+):neurotransmitter symporter (Snf family) O67854 O67854_AQUAE Aquifex aeolicus 3 0.9448
Sulfotransferase 2A1 Q06520 ST2A1_HUMAN Homo sapiens 3 0.9413
Sulfotransferase 2A1 Q06520 ST2A1_HUMAN Homo sapiens 3 0.9413
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A Q9Y233 PDE10_HUMAN Homo sapiens 3 0.9405
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A Q9Y233 PDE10_HUMAN Homo sapiens 3 0.9405
Matrix metalloproteinase-9 P14780 MMP9_HUMAN Homo sapiens 3 0.9388
Matrix metalloproteinase-9 P14780 MMP9_HUMAN Homo sapiens 3 0.9388
Cathepsin S P25774 CATS_HUMAN Homo sapiens 3 0.9385
Cathepsin S P25774 CATS_HUMAN Homo sapiens 3 0.9385
Pentaerythritol tetranitrate reductase P71278 P71278_ENTCL Enterobacter cloacae 3 0.9373
Pentaerythritol tetranitrate reductase P71278 P71278_ENTCL Enterobacter cloacae 3 0.9373
Serine/threonine-protein kinase pim-1 P11309 PIM1_HUMAN Homo sapiens 3 0.9343
Serine/threonine-protein kinase pim-1 P11309 PIM1_HUMAN Homo sapiens 3 0.9343
High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A O76083 PDE9A_HUMAN Homo sapiens 3 0.9314
High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A O76083 PDE9A_HUMAN Homo sapiens 3 0.9314
Chitinase A Q9AMP1 Q9AMP1_VIBHA Vibrio harveyi 3 0.9303
Chitinase A Q9AMP1 Q9AMP1_VIBHA Vibrio harveyi 3 0.9303
Cytochrome P450 monooxygenase Q5YNS8 Q5YNS8_NOCFA Nocardia farcinica 3 0.9273
Cytochrome P450 monooxygenase Q5YNS8 Q5YNS8_NOCFA Nocardia farcinica 3 0.9273
Cytochrome P450 monooxygenase Q5YNS8 Q5YNS8_NOCFA Nocardia farcinica 3 0.9219
Cytochrome P450 monooxygenase Q5YNS8 Q5YNS8_NOCFA Nocardia farcinica 3 0.9219
Cytochrome P450 monooxygenase Q5YNS8 Q5YNS8_NOCFA Nocardia farcinica 3 0.9175
Cytochrome P450 monooxygenase Q5YNS8 Q5YNS8_NOCFA Nocardia farcinica 3 0.9175
Squalene synthase P37268 FDFT_HUMAN Homo sapiens 3 0.9174
Squalene synthase P37268 FDFT_HUMAN Homo sapiens 3 0.9174
HTH-type transcriptional regulator EthR P9WMC1 ETHR_MYCTU Mycobacterium tuberculosis 3 0.9170
HTH-type transcriptional regulator EthR P9WMC1 ETHR_MYCTU Mycobacterium tuberculosis 3 0.9170
Sex hormone-binding globulin P04278 SHBG_HUMAN Homo sapiens 3 0.9148
Sex hormone-binding globulin P04278 SHBG_HUMAN Homo sapiens 3 0.9148
Sulfotransferase 2A1 Q06520 ST2A1_HUMAN Homo sapiens 3 0.9071
Sulfotransferase 2A1 Q06520 ST2A1_HUMAN Homo sapiens 3 0.9071
Aromatase P11511 CP19A_HUMAN Homo sapiens 3 0.9068
Aromatase P11511 CP19A_HUMAN Homo sapiens 3 0.9068
Protoporphyrinogen oxidase P50336 PPOX_HUMAN Homo sapiens 3 0.9047
Protoporphyrinogen oxidase P50336 PPOX_HUMAN Homo sapiens 3 0.9047
Steroid Delta-isomerase P00947 SDIS_COMTE Comamonas testosteroni 3 0.9035
Steroid Delta-isomerase P00947 SDIS_COMTE Comamonas testosteroni 3 0.9035
Cathepsin S P25774 CATS_HUMAN Homo sapiens 3 0.9025
Cathepsin S P25774 CATS_HUMAN Homo sapiens 3 0.9025
Gag-Pol polyprotein P04585 POL_HV1H2 Human immunodeficiency virus type 1 group M subtype B 3 0.9001
Gag-Pol polyprotein P04585 POL_HV1H2 Human immunodeficiency virus type 1 group M subtype B 3 0.9001
Basic phospholipase A2 VRV-PL-VIIIa P59071 PA2B8_DABRR Daboia russelii 3 0.8998
Basic phospholipase A2 VRV-PL-VIIIa P59071 PA2B8_DABRR Daboia russelii 3 0.8998
Cytochrome P450 2A6 P11509 CP2A6_HUMAN Homo sapiens 3 0.8967
Cytochrome P450 2A6 P11509 CP2A6_HUMAN Homo sapiens 3 0.8967
Proliferating cell nuclear antigen P12004 PCNA_HUMAN Homo sapiens 3 0.8958
Proliferating cell nuclear antigen P12004 PCNA_HUMAN Homo sapiens 3 0.8958
Steroid Delta-isomerase P07445 SDIS_PSEPU Pseudomonas putida 2 0.8902
Steroid Delta-isomerase P07445 SDIS_PSEPU Pseudomonas putida 2 0.8902
3',5'-cyclic-AMP phosphodiesterase 4D Q08499 PDE4D_HUMAN Homo sapiens 3 0.8872
3',5'-cyclic-AMP phosphodiesterase 4D Q08499 PDE4D_HUMAN Homo sapiens 3 0.8872
Steroid Delta-isomerase P00947 SDIS_COMTE Comamonas testosteroni 3 0.8834
Steroid Delta-isomerase P00947 SDIS_COMTE Comamonas testosteroni 3 0.8834
Androgen receptor P10275 ANDR_HUMAN Homo sapiens 3 0.8832
Androgen receptor P10275 ANDR_HUMAN Homo sapiens 3 0.8832
Protoporphyrinogen oxidase P50336 PPOX_HUMAN Homo sapiens 3 0.8816
Protoporphyrinogen oxidase P50336 PPOX_HUMAN Homo sapiens 3 0.8816
Steroid Delta-isomerase P00947 SDIS_COMTE Comamonas testosteroni 3 0.8779
Steroid Delta-isomerase P00947 SDIS_COMTE Comamonas testosteroni 3 0.8779
Androgen receptor P10275 ANDR_HUMAN Homo sapiens 3 0.8753
Androgen receptor P10275 ANDR_HUMAN Homo sapiens 3 0.8753
3-alpha-hydroxysteroid dehydrogenase P23457 DIDH_RAT Rattus norvegicus 3 0.8734
3-alpha-hydroxysteroid dehydrogenase P23457 DIDH_RAT Rattus norvegicus 3 0.8734
Sulfotransferase 2B1 O00204 ST2B1_HUMAN Homo sapiens 2 0.8725
Sulfotransferase 2B1 O00204 ST2B1_HUMAN Homo sapiens 2 0.8725
Cytochrome P450 2A6 P11509 CP2A6_HUMAN Homo sapiens 3 0.8709
Cytochrome P450 2A6 P11509 CP2A6_HUMAN Homo sapiens 3 0.8709
Aldo-keto reductase family 1 member D1 P51857 AK1D1_HUMAN Homo sapiens 3 0.8709
Aldo-keto reductase family 1 member D1 P51857 AK1D1_HUMAN Homo sapiens 3 0.8709
Aldo-keto reductase family 1 member C1 Q04828 AK1C1_HUMAN Homo sapiens 3 0.8635
Aldo-keto reductase family 1 member C1 Q04828 AK1C1_HUMAN Homo sapiens 3 0.8635
Steroid 21-hydroxylase P08686 CP21A_HUMAN Homo sapiens 3 0.8612
Steroid 21-hydroxylase P08686 CP21A_HUMAN Homo sapiens 3 0.8612
Tubulin alpha chain D0VWZ0 D0VWZ0_SHEEP Ovis aries 3 0.8564
Tubulin alpha chain D0VWZ0 D0VWZ0_SHEEP Ovis aries 3 0.8564
Beta-2 adrenergic receptor P07550 ADRB2_HUMAN Homo sapiens 2 0.8553
Beta-2 adrenergic receptor P07550 ADRB2_HUMAN Homo sapiens 2 0.8553
Aldo-keto reductase family 1 member D1 P51857 AK1D1_HUMAN Homo sapiens 3 0.8536
Aldo-keto reductase family 1 member D1 P51857 AK1D1_HUMAN Homo sapiens 3 0.8536
Tubulin alpha-1B chain P81947 TBA1B_BOVIN Bos taurus 3 0.8528
Tubulin alpha-1B chain P81947 TBA1B_BOVIN Bos taurus 3 0.8528
Eugenol synthase 1 Q15GI4 EGS1_OCIBA Ocimum basilicum 3 0.8467
Eugenol synthase 1 Q15GI4 EGS1_OCIBA Ocimum basilicum 3 0.8467
Aldo-keto reductase family 1 member D1 P51857 AK1D1_HUMAN Homo sapiens 3 0.8464
Aldo-keto reductase family 1 member D1 P51857 AK1D1_HUMAN Homo sapiens 3 0.8464
Sex hormone-binding globulin P04278 SHBG_HUMAN Homo sapiens 3 0.8441
Sex hormone-binding globulin P04278 SHBG_HUMAN Homo sapiens 3 0.8441
Soluble acetylcholine receptor Q8WSF8 Q8WSF8_APLCA Aplysia californica 3 0.8423
Soluble acetylcholine receptor Q8WSF8 Q8WSF8_APLCA Aplysia californica 3 0.8423
Enoyl-ACP reductase Q9BJJ9 Q9BJJ9_PLAFA Plasmodium falciparum 2 0.8414
Enoyl-ACP reductase Q9BJJ9 Q9BJJ9_PLAFA Plasmodium falciparum 2 0.8414
Steroid Delta-isomerase P07445 SDIS_PSEPU Pseudomonas putida 3 0.8382
Steroid Delta-isomerase P07445 SDIS_PSEPU Pseudomonas putida 3 0.8382
Dipeptidyl peptidase 4 P27487 DPP4_HUMAN Homo sapiens 3 0.8357
Dipeptidyl peptidase 4 P27487 DPP4_HUMAN Homo sapiens 3 0.8357
Putative ketoacyl reductase P16544 ACT3_STRCO Streptomyces coelicolor / M145) 3 0.8344
Putative ketoacyl reductase P16544 ACT3_STRCO Streptomyces coelicolor / M145) 3 0.8344
ADP-ribosylation factor 1 P84080 ARF1_BOVIN Bos taurus 3 0.8332
ADP-ribosylation factor 1 P84080 ARF1_BOVIN Bos taurus 3 0.8332
ADP-ribosylation factor 1 P84077 ARF1_HUMAN Homo sapiens 2 0.8327
ADP-ribosylation factor 1 P84077 ARF1_HUMAN Homo sapiens 2 0.8327
Aldo-keto reductase family 1 member D1 P51857 AK1D1_HUMAN Homo sapiens 3 0.8312
Aldo-keto reductase family 1 member D1 P51857 AK1D1_HUMAN Homo sapiens 3 0.8312
cGMP-specific 3',5'-cyclic phosphodiesterase O76074 PDE5A_HUMAN Homo sapiens 3 0.8258
cGMP-specific 3',5'-cyclic phosphodiesterase O76074 PDE5A_HUMAN Homo sapiens 3 0.8258
4,4'-diapophytoene synthase A9JQL9 CRTM_STAAU Staphylococcus aureus 2 0.8256
4,4'-diapophytoene synthase A9JQL9 CRTM_STAAU Staphylococcus aureus 2 0.8256
Steroid Delta-isomerase P07445 SDIS_PSEPU Pseudomonas putida 3 0.8252
Steroid Delta-isomerase P07445 SDIS_PSEPU Pseudomonas putida 3 0.8252
Mineralocorticoid receptor P08235 MCR_HUMAN Homo sapiens 3 0.8251
Mineralocorticoid receptor P08235 MCR_HUMAN Homo sapiens 3 0.8251
Ferrochelatase, mitochondrial P22830 HEMH_HUMAN Homo sapiens 2 0.8167
Ferrochelatase, mitochondrial P22830 HEMH_HUMAN Homo sapiens 2 0.8167
Serine/threonine-protein kinase Chk1 O14757 CHK1_HUMAN Homo sapiens 3 0.8160
Serine/threonine-protein kinase Chk1 O14757 CHK1_HUMAN Homo sapiens 3 0.8160
Dihydroorotate dehydrogenase (quinone), mitochondrial Q08210 PYRD_PLAF7 Plasmodium falciparum 3 0.8156
Dihydroorotate dehydrogenase (quinone), mitochondrial Q08210 PYRD_PLAF7 Plasmodium falciparum 3 0.8156
Mitogen-activated protein kinase 14 Q16539 MK14_HUMAN Homo sapiens 3 0.8147
Mitogen-activated protein kinase 14 Q16539 MK14_HUMAN Homo sapiens 3 0.8147
Putative ketoacyl reductase P16544 ACT3_STRCO Streptomyces coelicolor / M145) 2 0.8146
Putative ketoacyl reductase P16544 ACT3_STRCO Streptomyces coelicolor / M145) 2 0.8146
Androgen receptor P10275 ANDR_HUMAN Homo sapiens 3 0.8126
Androgen receptor P10275 ANDR_HUMAN Homo sapiens 3 0.8126
Androgen receptor P10275 ANDR_HUMAN Homo sapiens 3 0.8125
Androgen receptor P10275 ANDR_HUMAN Homo sapiens 3 0.8125
Androgen receptor P10275 ANDR_HUMAN Homo sapiens 3 0.8120
Androgen receptor P10275 ANDR_HUMAN Homo sapiens 3 0.8120
A disintegrin and metalloproteinase with thrombospondin motifs 5 Q9UNA0 ATS5_HUMAN Homo sapiens 3 0.8097
A disintegrin and metalloproteinase with thrombospondin motifs 5 Q9UNA0 ATS5_HUMAN Homo sapiens 3 0.8097
Serine/threonine-protein kinase Chk1 O14757 CHK1_HUMAN Homo sapiens 3 0.8095
Serine/threonine-protein kinase Chk1 O14757 CHK1_HUMAN Homo sapiens 3 0.8095
17-beta-hydroxysteroid dehydrogenase 14 Q9BPX1 DHB14_HUMAN Homo sapiens 2 0.8085
17-beta-hydroxysteroid dehydrogenase 14 Q9BPX1 DHB14_HUMAN Homo sapiens 2 0.8085
Androgen receptor P10275 ANDR_HUMAN Homo sapiens 3 0.8078
Androgen receptor P10275 ANDR_HUMAN Homo sapiens 3 0.8078
Sex hormone-binding globulin P04278 SHBG_HUMAN Homo sapiens 3 0.8076
Sex hormone-binding globulin P04278 SHBG_HUMAN Homo sapiens 3 0.8076
Androgen receptor O97775 ANDR_PANTR Pan troglodytes 3 0.8070
Androgen receptor O97775 ANDR_PANTR Pan troglodytes 3 0.8070
Androgen receptor P10275 ANDR_HUMAN Homo sapiens 3 0.8062
Androgen receptor P10275 ANDR_HUMAN Homo sapiens 3 0.8062
Androgen receptor O97775 ANDR_PANTR Pan troglodytes 3 0.8058
Androgen receptor O97775 ANDR_PANTR Pan troglodytes 3 0.8058
Androgen receptor P10275 ANDR_HUMAN Homo sapiens 3 0.8054
Androgen receptor P10275 ANDR_HUMAN Homo sapiens 3 0.8054
Androgen receptor P10275 ANDR_HUMAN Homo sapiens 3 0.8053
Androgen receptor P10275 ANDR_HUMAN Homo sapiens 3 0.8053
Androgen receptor P10275 ANDR_HUMAN Homo sapiens 3 0.8053
Androgen receptor P10275 ANDR_HUMAN Homo sapiens 3 0.8053
ATP synthase subunit alpha, mitochondrial P19483 ATPA_BOVIN Bos taurus 3 0.8051
ATP synthase subunit alpha, mitochondrial P19483 ATPA_BOVIN Bos taurus 3 0.8051
Androgen receptor O97775 ANDR_PANTR Pan troglodytes 3 0.8051
Androgen receptor O97775 ANDR_PANTR Pan troglodytes 3 0.8051
Androgen receptor O97775 ANDR_PANTR Pan troglodytes 3 0.8049
Androgen receptor P10275 ANDR_HUMAN Homo sapiens 3 0.8049
Androgen receptor O97775 ANDR_PANTR Pan troglodytes 3 0.8049
Androgen receptor P10275 ANDR_HUMAN Homo sapiens 3 0.8049
Androgen receptor P10275 ANDR_HUMAN Homo sapiens 3 0.8048
Androgen receptor P10275 ANDR_HUMAN Homo sapiens 3 0.8048
Androgen receptor P10275 ANDR_HUMAN Homo sapiens 3 0.8046
Androgen receptor P10275 ANDR_HUMAN Homo sapiens 3 0.8046
Androgen receptor O97775 ANDR_PANTR Pan troglodytes 3 0.8045
Androgen receptor O97775 ANDR_PANTR Pan troglodytes 3 0.8045
Androgen receptor P10275 ANDR_HUMAN Homo sapiens 3 0.8043
Androgen receptor P10275 ANDR_HUMAN Homo sapiens 3 0.8043
Mineralocorticoid receptor P08235 MCR_HUMAN Homo sapiens 3 0.8042
Mineralocorticoid receptor P08235 MCR_HUMAN Homo sapiens 3 0.8042
Sex hormone-binding globulin P04278 SHBG_HUMAN Homo sapiens 3 0.8042
Androgen receptor P10275 ANDR_HUMAN Homo sapiens 3 0.8042
Androgen receptor P10275 ANDR_HUMAN Homo sapiens 3 0.8042
Sex hormone-binding globulin P04278 SHBG_HUMAN Homo sapiens 3 0.8042
Androgen receptor P10275 ANDR_HUMAN Homo sapiens 3 0.8040
Androgen receptor P10275 ANDR_HUMAN Homo sapiens 3 0.8040
Fatty acid-binding protein, liver P80226 FABPL_CHICK Gallus gallus 2 0.8037
Fatty acid-binding protein, liver P80226 FABPL_CHICK Gallus gallus 2 0.8037
Gastrotropin Q6IMW5 Q6IMW5_DANRE Danio rerio 2 0.8036
Gastrotropin Q6IMW5 Q6IMW5_DANRE Danio rerio 2 0.8036
Basic phospholipase A2 VRV-PL-VIIIa P59071 PA2B8_DABRR Daboia russelii 2 0.8025
Basic phospholipase A2 VRV-PL-VIIIa P59071 PA2B8_DABRR Daboia russelii 2 0.8025
Androgen receptor P10275 ANDR_HUMAN Homo sapiens 3 0.8024
Androgen receptor P10275 ANDR_HUMAN Homo sapiens 3 0.8024
Androgen receptor O97775 ANDR_PANTR Pan troglodytes 3 0.8022
Androgen receptor O97775 ANDR_PANTR Pan troglodytes 3 0.8022
Androgen receptor P19091 ANDR_MOUSE Mus musculus 3 0.8021
Androgen receptor P19091 ANDR_MOUSE Mus musculus 3 0.8021
Androgen receptor P10275 ANDR_HUMAN Homo sapiens 3 0.8013
Androgen receptor P10275 ANDR_HUMAN Homo sapiens 3 0.8013
Hexokinase-4 P35557 HXK4_HUMAN Homo sapiens 3 0.8009
Hexokinase-4 P35557 HXK4_HUMAN Homo sapiens 3 0.8009
Proto-oncogene tyrosine-protein kinase receptor Ret P07949 RET_HUMAN Homo sapiens 3 0.8005
Androgen receptor O97775 ANDR_PANTR Pan troglodytes 3 0.8005
Proto-oncogene tyrosine-protein kinase receptor Ret P07949 RET_HUMAN Homo sapiens 3 0.8005
Androgen receptor O97775 ANDR_PANTR Pan troglodytes 3 0.8005
Androgen receptor P10275 ANDR_HUMAN Homo sapiens 3 0.8003
Androgen receptor P10275 ANDR_HUMAN Homo sapiens 3 0.8003
Lactoylglutathione lyase Q9CPU0 LGUL_MOUSE Mus musculus 2 0.8003
Lactoylglutathione lyase Q9CPU0 LGUL_MOUSE Mus musculus 2 0.8003
Androgen receptor P10275 ANDR_HUMAN Homo sapiens 3 0.8003
Androgen receptor P10275 ANDR_HUMAN Homo sapiens 3 0.8003
Androgen receptor O97775 ANDR_PANTR Pan troglodytes 3 0.7995
Androgen receptor O97775 ANDR_PANTR Pan troglodytes 3 0.7995
Androgen receptor P10275 ANDR_HUMAN Homo sapiens 3 0.7995
Androgen receptor P10275 ANDR_HUMAN Homo sapiens 3 0.7995
Androgen receptor P10275 ANDR_HUMAN Homo sapiens 3 0.7993
Androgen receptor P10275 ANDR_HUMAN Homo sapiens 3 0.7993
Heat shock protein HSP 90-alpha P07900 HS90A_HUMAN Homo sapiens 3 0.7989
Androgen receptor P10275 ANDR_HUMAN Homo sapiens 3 0.7989
Androgen receptor P10275 ANDR_HUMAN Homo sapiens 3 0.7989
Heat shock protein HSP 90-alpha P07900 HS90A_HUMAN Homo sapiens 3 0.7989
Androgen receptor P10275 ANDR_HUMAN Homo sapiens 3 0.7982
Androgen receptor P10275 ANDR_HUMAN Homo sapiens 3 0.7982
Cytochrome P450 monooxygenase Q5YNS8 Q5YNS8_NOCFA Nocardia farcinica 3 0.7977
Cytochrome P450 monooxygenase Q5YNS8 Q5YNS8_NOCFA Nocardia farcinica 3 0.7977
Mineralocorticoid receptor P08235 MCR_HUMAN Homo sapiens 3 0.7976
Mineralocorticoid receptor P08235 MCR_HUMAN Homo sapiens 3 0.7976
Androgen receptor P10275 ANDR_HUMAN Homo sapiens 3 0.7973
Androgen receptor P10275 ANDR_HUMAN Homo sapiens 3 0.7973
Androgen receptor P10275 ANDR_HUMAN Homo sapiens 3 0.7971
NAD(P)H dehydrogenase [quinone] 1 P15559 NQO1_HUMAN Homo sapiens 3 0.7971
Androgen receptor P10275 ANDR_HUMAN Homo sapiens 3 0.7971
NAD(P)H dehydrogenase [quinone] 1 P15559 NQO1_HUMAN Homo sapiens 3 0.7971
Androgen receptor P10275 ANDR_HUMAN Homo sapiens 3 0.7969
Androgen receptor P10275 ANDR_HUMAN Homo sapiens 3 0.7969
Focal adhesion kinase 1 Q00944 FAK1_CHICK Gallus gallus 3 0.7968
Focal adhesion kinase 1 Q00944 FAK1_CHICK Gallus gallus 3 0.7968
17-beta-hydroxysteroid dehydrogenase type 1 P14061 DHB1_HUMAN Homo sapiens 2 0.7964
17-beta-hydroxysteroid dehydrogenase type 1 P14061 DHB1_HUMAN Homo sapiens 2 0.7964
Mineralocorticoid receptor P08235 MCR_HUMAN Homo sapiens 3 0.7959
Mineralocorticoid receptor P08235 MCR_HUMAN Homo sapiens 3 0.7959
Farnesyl pyrophosphate synthase P14324 FPPS_HUMAN Homo sapiens 2 0.7956
Farnesyl pyrophosphate synthase P14324 FPPS_HUMAN Homo sapiens 2 0.7956
Progesterone receptor P06401 PRGR_HUMAN Homo sapiens 3 0.7955
Progesterone receptor P06401 PRGR_HUMAN Homo sapiens 3 0.7955
Aldo-keto reductase family 1 member D1 P51857 AK1D1_HUMAN Homo sapiens 3 0.7954
Aldo-keto reductase family 1 member D1 P51857 AK1D1_HUMAN Homo sapiens 3 0.7954
Androgen receptor P10275 ANDR_HUMAN Homo sapiens 3 0.7953
Androgen receptor P10275 ANDR_HUMAN Homo sapiens 3 0.7953
Focal adhesion kinase 1 Q00944 FAK1_CHICK Gallus gallus 3 0.7953
Focal adhesion kinase 1 Q00944 FAK1_CHICK Gallus gallus 3 0.7953
Androgen receptor P10275 ANDR_HUMAN Homo sapiens 3 0.7949
Androgen receptor P10275 ANDR_HUMAN Homo sapiens 3 0.7949
Cell division cycle 7-related protein kinase O00311 CDC7_HUMAN Homo sapiens 3 0.7939
Cell division cycle 7-related protein kinase O00311 CDC7_HUMAN Homo sapiens 3 0.7939
Steroid Delta-isomerase P00947 SDIS_COMTE Comamonas testosteroni 3 0.7935
Steroid Delta-isomerase P00947 SDIS_COMTE Comamonas testosteroni 3 0.7935
Aromatase P11511 CP19A_HUMAN Homo sapiens 2 0.7930
Aromatase P11511 CP19A_HUMAN Homo sapiens 2 0.7930
Androgen receptor P10275 ANDR_HUMAN Homo sapiens 3 0.7923
Androgen receptor P10275 ANDR_HUMAN Homo sapiens 3 0.7923
Androgen receptor P10275 ANDR_HUMAN Homo sapiens 3 0.7920
Androgen receptor P10275 ANDR_HUMAN Homo sapiens 3 0.7920
Aldo-keto reductase family 1 member C2 P52895 AK1C2_HUMAN Homo sapiens 2 0.7906
Aldo-keto reductase family 1 member C2 P52895 AK1C2_HUMAN Homo sapiens 2 0.7906
Class B acid phosphatase Q540U1 APHA_SALTM Salmonella typhimurium 2 0.7905
Class B acid phosphatase Q540U1 APHA_SALTM Salmonella typhimurium 2 0.7905
Nuclear receptor coactivator 2 Q15596 NCOA2_HUMAN Homo sapiens 3 0.7887
Nuclear receptor coactivator 2 Q15596 NCOA2_HUMAN Homo sapiens 3 0.7887
Focal adhesion kinase 1 Q00944 FAK1_CHICK Gallus gallus 3 0.7885
Focal adhesion kinase 1 Q00944 FAK1_CHICK Gallus gallus 3 0.7885
Androgen receptor P10275 ANDR_HUMAN Homo sapiens 3 0.7884
Androgen receptor P10275 ANDR_HUMAN Homo sapiens 3 0.7884
Sex hormone-binding globulin P04278 SHBG_HUMAN Homo sapiens 3 0.7880
Sex hormone-binding globulin P04278 SHBG_HUMAN Homo sapiens 3 0.7880
Androgen receptor P10275 ANDR_HUMAN Homo sapiens 3 0.7875
Androgen receptor P10275 ANDR_HUMAN Homo sapiens 3 0.7875
17-beta-hydroxysteroid dehydrogenase type 1 P14061 DHB1_HUMAN Homo sapiens 2 0.7869
Collagenase 3 P45452 MMP13_HUMAN Homo sapiens 3 0.7869
17-beta-hydroxysteroid dehydrogenase type 1 P14061 DHB1_HUMAN Homo sapiens 2 0.7869
Collagenase 3 P45452 MMP13_HUMAN Homo sapiens 3 0.7869
Mineralocorticoid receptor P08235 MCR_HUMAN Homo sapiens 3 0.7865
Mineralocorticoid receptor P08235 MCR_HUMAN Homo sapiens 3 0.7865
17-beta-hydroxysteroid dehydrogenase type 1 P14061 DHB1_HUMAN Homo sapiens 2 0.7860
17-beta-hydroxysteroid dehydrogenase type 1 P14061 DHB1_HUMAN Homo sapiens 2 0.7860
3',5'-cyclic-AMP phosphodiesterase 4D Q08499 PDE4D_HUMAN Homo sapiens 3 0.7849
3',5'-cyclic-AMP phosphodiesterase 4D Q08499 PDE4D_HUMAN Homo sapiens 3 0.7849
Interleukin-2 P60568 IL2_HUMAN Homo sapiens 2 0.7847
Interleukin-2 P60568 IL2_HUMAN Homo sapiens 2 0.7847
Steroid Delta-isomerase P07445 SDIS_PSEPU Pseudomonas putida 2 0.7841
Steroid Delta-isomerase P07445 SDIS_PSEPU Pseudomonas putida 2 0.7841
Renin P00797 RENI_HUMAN Homo sapiens 2 0.7831
Renin P00797 RENI_HUMAN Homo sapiens 2 0.7831
Androgen receptor P10275 ANDR_HUMAN Homo sapiens 3 0.7823
Androgen receptor P10275 ANDR_HUMAN Homo sapiens 3 0.7823
Prostaglandin reductase 2 Q8N8N7 PTGR2_HUMAN Homo sapiens 2 0.7822
Prostaglandin reductase 2 Q8N8N7 PTGR2_HUMAN Homo sapiens 2 0.7822
Serine/threonine-protein kinase Chk2 O96017 CHK2_HUMAN Homo sapiens 2 0.7822
Serine/threonine-protein kinase Chk2 O96017 CHK2_HUMAN Homo sapiens 2 0.7822
Avidin P02701 AVID_CHICK Gallus gallus 3 0.7813
Avidin P02701 AVID_CHICK Gallus gallus 3 0.7813
4,4'-diapophytoene synthase A9JQL9 CRTM_STAAU Staphylococcus aureus 2 0.7811
4,4'-diapophytoene synthase A9JQL9 CRTM_STAAU Staphylococcus aureus 2 0.7811
Glycogen phosphorylase, muscle form P00489 PYGM_RABIT Oryctolagus cuniculus 3 0.7808
Glycogen phosphorylase, muscle form P00489 PYGM_RABIT Oryctolagus cuniculus 3 0.7808
Lactoylglutathione lyase Q04760 LGUL_HUMAN Homo sapiens 2 0.7804
Cyclin-dependent kinase 2 P24941 CDK2_HUMAN Homo sapiens 2 0.7804
Cyclin-dependent kinase 2 P24941 CDK2_HUMAN Homo sapiens 2 0.7804
Lactoylglutathione lyase Q04760 LGUL_HUMAN Homo sapiens 2 0.7804
CmeR Q7B8P6 Q7B8P6_CAMJU Campylobacter jejuni 2 0.7800
CmeR Q7B8P6 Q7B8P6_CAMJU Campylobacter jejuni 2 0.7800
Nuclear receptor ROR-gamma P51449 RORG_HUMAN Homo sapiens 2 0.7796
Nuclear receptor ROR-gamma P51449 RORG_HUMAN Homo sapiens 2 0.7796
Soluble cytochrome b562 P0ABE7 C562_ECOLX Escherichia coli 2 0.7795
Soluble cytochrome b562 P0ABE7 C562_ECOLX Escherichia coli 2 0.7795
Macrophage metalloelastase P39900 MMP12_HUMAN Homo sapiens 2 0.7791
Macrophage metalloelastase P39900 MMP12_HUMAN Homo sapiens 2 0.7791
Catalase-peroxidase 2 O59651 KATG2_HALMA Haloarcula marismortui 2 0.7789
Cyclin-dependent kinase 2 P24941 CDK2_HUMAN Homo sapiens 2 0.7789
Catalase-peroxidase 2 O59651 KATG2_HALMA Haloarcula marismortui 2 0.7789
Cyclin-dependent kinase 2 P24941 CDK2_HUMAN Homo sapiens 2 0.7789
Casein kinase II subunit alpha P68400 CSK21_HUMAN Homo sapiens 3 0.7788
Casein kinase II subunit alpha P68400 CSK21_HUMAN Homo sapiens 3 0.7788
Serine/threonine-protein kinase pim-1 P11309 PIM1_HUMAN Homo sapiens 3 0.7782
Serine/threonine-protein kinase pim-1 P11309 PIM1_HUMAN Homo sapiens 3 0.7782
17-beta-hydroxysteroid dehydrogenase type 1 P14061 DHB1_HUMAN Homo sapiens 2 0.7781
17-beta-hydroxysteroid dehydrogenase type 1 P14061 DHB1_HUMAN Homo sapiens 2 0.7781
Acetylcholinesterase P22303 ACES_HUMAN Homo sapiens 2 0.7771
Acetylcholinesterase P22303 ACES_HUMAN Homo sapiens 2 0.7771
cGMP-dependent 3',5'-cyclic phosphodiesterase O00408 PDE2A_HUMAN Homo sapiens 2 0.7766
cGMP-dependent 3',5'-cyclic phosphodiesterase O00408 PDE2A_HUMAN Homo sapiens 2 0.7766
Beta-secretase 1 P56817 BACE1_HUMAN Homo sapiens 2 0.7764
Beta-secretase 1 P56817 BACE1_HUMAN Homo sapiens 2 0.7764
Aldo-keto reductase family 1 member D1 P51857 AK1D1_HUMAN Homo sapiens 2 0.7745
Aldo-keto reductase family 1 member D1 P51857 AK1D1_HUMAN Homo sapiens 2 0.7745
Retinol-binding protein 4 P18902 RET4_BOVIN Bos taurus 2 0.7744
Retinol-binding protein 4 P18902 RET4_BOVIN Bos taurus 2 0.7744
Androgen receptor P10275 ANDR_HUMAN Homo sapiens 3 0.7744
Androgen receptor P10275 ANDR_HUMAN Homo sapiens 3 0.7744
Biphenyl-2,3-diol 1,2-dioxygenase P17297 BPHC_PSES1 Pseudomonas sp 2 0.7738
Biphenyl-2,3-diol 1,2-dioxygenase P17297 BPHC_PSES1 Pseudomonas sp 2 0.7738
Aldo-keto reductase family 1 member C2 P52895 AK1C2_HUMAN Homo sapiens 2 0.7731
Aldo-keto reductase family 1 member C2 P52895 AK1C2_HUMAN Homo sapiens 2 0.7731
Mitogen-activated protein kinase 14 Q16539 MK14_HUMAN Homo sapiens 2 0.7730
Mitogen-activated protein kinase 14 Q16539 MK14_HUMAN Homo sapiens 2 0.7730
Casein kinase II subunit alpha P68400 CSK21_HUMAN Homo sapiens 2 0.7726
Casein kinase II subunit alpha P68400 CSK21_HUMAN Homo sapiens 2 0.7726
RNA-dependent RNA polymerase Q6A562 Q6A562_9VIRU Thosea asigna virus 2 0.7724
RNA-dependent RNA polymerase Q6A562 Q6A562_9VIRU Thosea asigna virus 2 0.7724
Lactotransferrin P24627 TRFL_BOVIN Bos taurus 2 0.7723
Lactotransferrin P24627 TRFL_BOVIN Bos taurus 2 0.7723
Beta-secretase 1 P56817 BACE1_HUMAN Homo sapiens 2 0.7721
Beta-secretase 1 P56817 BACE1_HUMAN Homo sapiens 2 0.7721
11-beta-hydroxysteroid dehydrogenase 1 P50172 DHI1_MOUSE Mus musculus 2 0.7721
11-beta-hydroxysteroid dehydrogenase 1 P50172 DHI1_MOUSE Mus musculus 2 0.7721
High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A O76083 PDE9A_HUMAN Homo sapiens 2 0.7720
High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A O76083 PDE9A_HUMAN Homo sapiens 2 0.7720
Beta sliding clamp P0A988 DPO3B_ECOLI Escherichia coli 2 0.7707
Beta sliding clamp P0A988 DPO3B_ECOLI Escherichia coli 2 0.7707
Casein kinase II subunit alpha P68400 CSK21_HUMAN Homo sapiens 3 0.7705
Casein kinase II subunit alpha P68400 CSK21_HUMAN Homo sapiens 3 0.7705
Fatty acid-binding protein, adipocyte P04117 FABP4_MOUSE Mus musculus 2 0.7702
Fatty acid-binding protein, adipocyte P04117 FABP4_MOUSE Mus musculus 2 0.7702
High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A O76083 PDE9A_HUMAN Homo sapiens 2 0.7701
Enoyl-[acyl-carrier-protein] reductase [NADH] P9WGR1 INHA_MYCTU Mycobacterium tuberculosis 2 0.7701
Enoyl-[acyl-carrier-protein] reductase [NADH] P9WGR1 INHA_MYCTU Mycobacterium tuberculosis 2 0.7701
High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A O76083 PDE9A_HUMAN Homo sapiens 2 0.7701
Mycocyclosin synthase P9WPP7 CP121_MYCTU Mycobacterium tuberculosis 2 0.7701
Mycocyclosin synthase P9WPP7 CP121_MYCTU Mycobacterium tuberculosis 2 0.7701
Cis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase Q46381 BPHB_COMTE Comamonas testosteroni 3 0.7684
Cis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase Q46381 BPHB_COMTE Comamonas testosteroni 3 0.7684
Terminal oxygenase component of carbazole Q84II6 Q84II6_JANS3 Janthinobacterium sp 2 0.7683
Terminal oxygenase component of carbazole Q84II6 Q84II6_JANS3 Janthinobacterium sp 2 0.7683
Androgen receptor P10275 ANDR_HUMAN Homo sapiens 3 0.7683
Androgen receptor P10275 ANDR_HUMAN Homo sapiens 3 0.7683
CmeR Q7B8P6 Q7B8P6_CAMJU Campylobacter jejuni 2 0.7682
CmeR Q7B8P6 Q7B8P6_CAMJU Campylobacter jejuni 2 0.7682
Glucan 1,3-beta-glucosidase P29717 EXG1_CANAL Candida albicans 2 0.7681
Glucan 1,3-beta-glucosidase P29717 EXG1_CANAL Candida albicans 2 0.7681
Tetracycline repressor protein class D P0ACT4 TETR4_ECOLX Escherichia coli 2 0.7677
Tetracycline repressor protein class D P0ACT4 TETR4_ECOLX Escherichia coli 2 0.7677
Neocarzinostatin P0A3R9 NCZS_STRCZ Streptomyces carzinostaticus 2 0.7664
ADP-ribosylation factor 1 P84080 ARF1_BOVIN Bos taurus 2 0.7664
ADP-ribosylation factor 1 P84080 ARF1_BOVIN Bos taurus 2 0.7664
Neocarzinostatin P0A3R9 NCZS_STRCZ Streptomyces carzinostaticus 2 0.7664
Glucocorticoid receptor P04150 GCR_HUMAN Homo sapiens 3 0.7658
Glucocorticoid receptor P04150 GCR_HUMAN Homo sapiens 3 0.7658
1-deoxy-D-xylulose 5-phosphate reductoisomerase P45568 DXR_ECOLI Escherichia coli 2 0.7654
1-deoxy-D-xylulose 5-phosphate reductoisomerase P45568 DXR_ECOLI Escherichia coli 2 0.7654
Thymidylate synthase P00469 TYSY_LACCA Lacticaseibacillus casei 2 0.7652
Thymidylate synthase P00469 TYSY_LACCA Lacticaseibacillus casei 2 0.7652
cAMP-dependent protein kinase catalytic subunit alpha P00517 KAPCA_BOVIN Bos taurus 2 0.7649
cAMP-dependent protein kinase catalytic subunit alpha P00517 KAPCA_BOVIN Bos taurus 2 0.7649
Collagenase 3 P45452 MMP13_HUMAN Homo sapiens 2 0.7646
Biphenyl-2,3-diol 1,2-dioxygenase P17297 BPHC_PSES1 Pseudomonas sp 2 0.7646
Collagenase 3 P45452 MMP13_HUMAN Homo sapiens 2 0.7646
Biphenyl-2,3-diol 1,2-dioxygenase P17297 BPHC_PSES1 Pseudomonas sp 2 0.7646
Serine/threonine-protein kinase pim-1 P11309 PIM1_HUMAN Homo sapiens 3 0.7644
Macrophage metalloelastase P39900 MMP12_HUMAN Homo sapiens 3 0.7644
Serine/threonine-protein kinase pim-1 P11309 PIM1_HUMAN Homo sapiens 3 0.7644
Macrophage metalloelastase P39900 MMP12_HUMAN Homo sapiens 3 0.7644
Rhodopsin P02699 OPSD_BOVIN Bos taurus 2 0.7640
Chitinase A Q9AMP1 Q9AMP1_VIBHA Vibrio harveyi 2 0.7640
Chitinase A Q9AMP1 Q9AMP1_VIBHA Vibrio harveyi 2 0.7640
Rhodopsin P02699 OPSD_BOVIN Bos taurus 2 0.7640
Carbonic anhydrase 2 P00918 CAH2_HUMAN Homo sapiens 3 0.7638
Carbonic anhydrase 2 P00918 CAH2_HUMAN Homo sapiens 3 0.7638
Neutrophil collagenase P22894 MMP8_HUMAN Homo sapiens 2 0.7637
Neutrophil collagenase P22894 MMP8_HUMAN Homo sapiens 2 0.7637
Heat shock protein HSP 90-alpha P07900 HS90A_HUMAN Homo sapiens 2 0.7633
Heat shock protein HSP 90-alpha P07900 HS90A_HUMAN Homo sapiens 2 0.7633
Cytohesin-2 Q99418 CYH2_HUMAN Homo sapiens 2 0.7631
Cytohesin-2 Q99418 CYH2_HUMAN Homo sapiens 2 0.7631
UDP-3-O-acyl-N-acetylglucosamine deacetylase P47205 LPXC_PSEAE Pseudomonas aeruginosa 3 0.7628
UDP-3-O-acyl-N-acetylglucosamine deacetylase P47205 LPXC_PSEAE Pseudomonas aeruginosa 3 0.7628
Beta-secretase 1 P56817 BACE1_HUMAN Homo sapiens 2 0.7627
Aldo-keto reductase family 1 member C2 P52895 AK1C2_HUMAN Homo sapiens 2 0.7627
Beta-secretase 1 P56817 BACE1_HUMAN Homo sapiens 2 0.7627
Aldo-keto reductase family 1 member C2 P52895 AK1C2_HUMAN Homo sapiens 2 0.7627
Sepiapterin reductase Q64105 SPRE_MOUSE Mus musculus 3 0.7625
Sepiapterin reductase Q64105 SPRE_MOUSE Mus musculus 3 0.7625
Angiopoietin-1 receptor Q02763 TIE2_HUMAN Homo sapiens 3 0.7624
Angiopoietin-1 receptor Q02763 TIE2_HUMAN Homo sapiens 3 0.7624
Aurora kinase A O14965 AURKA_HUMAN Homo sapiens 2 0.7613
Aurora kinase A O14965 AURKA_HUMAN Homo sapiens 2 0.7613
Casein kinase II subunit alpha P68400 CSK21_HUMAN Homo sapiens 3 0.7609
Casein kinase II subunit alpha P68400 CSK21_HUMAN Homo sapiens 3 0.7609
ATP-dependent molecular chaperone HSP82 P02829 HSP82_YEAST Saccharomyces cerevisiae 2 0.7608
ATP-dependent molecular chaperone HSP82 P02829 HSP82_YEAST Saccharomyces cerevisiae 2 0.7608
Serine/threonine-protein kinase pim-1 P11309 PIM1_HUMAN Homo sapiens 2 0.7602
Serine/threonine-protein kinase pim-1 P11309 PIM1_HUMAN Homo sapiens 2 0.7602
LIM domain kinase 1 P53667 LIMK1_HUMAN Homo sapiens 2 0.7598
Abscisic acid receptor PYL1 Q8VZS8 PYL1_ARATH Arabidopsis thaliana 2 0.7598
High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A O76083 PDE9A_HUMAN Homo sapiens 2 0.7598
11-beta-hydroxysteroid dehydrogenase 1 P28845 DHI1_HUMAN Homo sapiens 2 0.7598
11-beta-hydroxysteroid dehydrogenase 1 P28845 DHI1_HUMAN Homo sapiens 2 0.7598
LIM domain kinase 1 P53667 LIMK1_HUMAN Homo sapiens 2 0.7598
High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A O76083 PDE9A_HUMAN Homo sapiens 2 0.7598
Abscisic acid receptor PYL1 Q8VZS8 PYL1_ARATH Arabidopsis thaliana 2 0.7598
Peptidyl-prolyl cis-trans isomerase FKBP1A P62942 FKB1A_HUMAN Homo sapiens 2 0.7596
Peptidyl-prolyl cis-trans isomerase FKBP1A P62942 FKB1A_HUMAN Homo sapiens 2 0.7596
Macrophage metalloelastase P39900 MMP12_HUMAN Homo sapiens 3 0.7592
Serine/threonine-protein kinase pim-1 P11309 PIM1_HUMAN Homo sapiens 2 0.7592
Macrophage metalloelastase P39900 MMP12_HUMAN Homo sapiens 3 0.7592
Serine/threonine-protein kinase pim-1 P11309 PIM1_HUMAN Homo sapiens 2 0.7592
Transcriptional regulator, PadR-like family A2RI36 A2RI36_LACLM Lactococcus lactis subsp. cremoris 2 0.7590
Biphenyl-2,3-diol 1,2-dioxygenase P47228 BPHC_PARXL Paraburkholderia xenovorans 2 0.7590
Genome polyprotein P26663 POLG_HCVBK Hepatitis C virus genotype 1b 3 0.7590
Transcriptional regulator, PadR-like family A2RI36 A2RI36_LACLM Lactococcus lactis subsp. cremoris 2 0.7590
Biphenyl-2,3-diol 1,2-dioxygenase P47228 BPHC_PARXL Paraburkholderia xenovorans 2 0.7590
Genome polyprotein P26663 POLG_HCVBK Hepatitis C virus genotype 1b 3 0.7590
3'-5' exoribonuclease Rv2179c P9WJ73 EXRBN_MYCTU Mycobacterium tuberculosis 2 0.7579
3'-5' exoribonuclease Rv2179c P9WJ73 EXRBN_MYCTU Mycobacterium tuberculosis 2 0.7579
Alpha-1-acid glycoprotein 2 P19652 A1AG2_HUMAN Homo sapiens 2 0.7579
Alpha-1-acid glycoprotein 2 P19652 A1AG2_HUMAN Homo sapiens 2 0.7579
Sulfotransferase 2B1 O00204 ST2B1_HUMAN Homo sapiens 2 0.7576
Sulfotransferase 2B1 O00204 ST2B1_HUMAN Homo sapiens 2 0.7576
Dipeptidyl peptidase 4 P27487 DPP4_HUMAN Homo sapiens 2 0.7574
Dipeptidyl peptidase 4 P27487 DPP4_HUMAN Homo sapiens 2 0.7574
Methylketone synthase I E0YCS2 E0YCS2_SOLHA Solanum habrochaites 2 0.7573
Methylketone synthase I E0YCS2 E0YCS2_SOLHA Solanum habrochaites 2 0.7573
cGMP-dependent protein kinase 1 Q13976 KGP1_HUMAN Homo sapiens 2 0.7566
17-beta-hydroxysteroid dehydrogenase type 1 P14061 DHB1_HUMAN Homo sapiens 2 0.7566
17-beta-hydroxysteroid dehydrogenase type 1 P14061 DHB1_HUMAN Homo sapiens 2 0.7566
cGMP-dependent protein kinase 1 Q13976 KGP1_HUMAN Homo sapiens 2 0.7566
cAMP-dependent protein kinase type I-alpha regulatory subunit P00514 KAP0_BOVIN Bos taurus 2 0.7558
cAMP-dependent protein kinase type I-alpha regulatory subunit P00514 KAP0_BOVIN Bos taurus 2 0.7558
Bromodomain-containing protein 4 O60885 BRD4_HUMAN Homo sapiens 3 0.7556
Bromodomain-containing protein 4 O60885 BRD4_HUMAN Homo sapiens 3 0.7556
Enoyl-ACP reductase Q9BJJ9 Q9BJJ9_PLAFA Plasmodium falciparum 2 0.7551
Glutamate receptor 2 P42262 GRIA2_HUMAN Homo sapiens 2 0.7551
Glutamate receptor 2 P42262 GRIA2_HUMAN Homo sapiens 2 0.7551
Enoyl-ACP reductase Q9BJJ9 Q9BJJ9_PLAFA Plasmodium falciparum 2 0.7551
Steroid Delta-isomerase P00947 SDIS_COMTE Comamonas testosteroni 3 0.7548
Steroid Delta-isomerase P00947 SDIS_COMTE Comamonas testosteroni 3 0.7548
Tyrosine-protein kinase SYK P43405 KSYK_HUMAN Homo sapiens 2 0.7546
Hematopoietic prostaglandin D synthase O60760 HPGDS_HUMAN Homo sapiens 2 0.7546
Hematopoietic prostaglandin D synthase O60760 HPGDS_HUMAN Homo sapiens 2 0.7546
Tyrosine-protein kinase SYK P43405 KSYK_HUMAN Homo sapiens 2 0.7546
Death-associated protein kinase 1 P53355 DAPK1_HUMAN Homo sapiens 2 0.7544
Death-associated protein kinase 1 P53355 DAPK1_HUMAN Homo sapiens 2 0.7544
4,4'-diapophytoene synthase A9JQL9 CRTM_STAAU Staphylococcus aureus 2 0.7539
4,4'-diapophytoene synthase A9JQL9 CRTM_STAAU Staphylococcus aureus 2 0.7539
Putative HMP/thiamine-binding protein YkoF O34911 YKOF_BACSU Bacillus subtilis 2 0.7537
Putative HMP/thiamine-binding protein YkoF O34911 YKOF_BACSU Bacillus subtilis 2 0.7537
Pancreatic alpha-amylase P04746 AMYP_HUMAN Homo sapiens 2 0.7534
Pancreatic alpha-amylase P04746 AMYP_HUMAN Homo sapiens 2 0.7534
Prostaglandin G/H synthase 1 P05979 PGH1_SHEEP Ovis aries 2 0.7533
Prostaglandin G/H synthase 1 P05979 PGH1_SHEEP Ovis aries 2 0.7533
Mycocyclosin synthase P9WPP7 CP121_MYCTU Mycobacterium tuberculosis 2 0.7532
Mycocyclosin synthase P9WPP7 CP121_MYCTU Mycobacterium tuberculosis 2 0.7532
Terminal oxygenase component of carbazole Q84II6 Q84II6_JANS3 Janthinobacterium sp 2 0.7532
Terminal oxygenase component of carbazole Q84II6 Q84II6_JANS3 Janthinobacterium sp 2 0.7532
Anthranilate phosphoribosyltransferase P9WFX5 TRPD_MYCTU Mycobacterium tuberculosis 2 0.7530
Anthranilate phosphoribosyltransferase P9WFX5 TRPD_MYCTU Mycobacterium tuberculosis 2 0.7530
Tetracycline repressor protein class H P51561 TETR8_PASMD Pasteurella multocida 2 0.7529
Serine/threonine-protein kinase pim-1 P11309 PIM1_HUMAN Homo sapiens 3 0.7529
Serine/threonine-protein kinase pim-1 P11309 PIM1_HUMAN Homo sapiens 3 0.7529
Tetracycline repressor protein class H P51561 TETR8_PASMD Pasteurella multocida 2 0.7529
Tetracycline repressor protein class D P0ACT4 TETR4_ECOLX Escherichia coli 2 0.7528
Tetracycline repressor protein class D P0ACT4 TETR4_ECOLX Escherichia coli 2 0.7528
Enoyl-ACP reductase Q9BJJ9 Q9BJJ9_PLAFA Plasmodium falciparum 2 0.7521
Enoyl-ACP reductase Q9BJJ9 Q9BJJ9_PLAFA Plasmodium falciparum 2 0.7521
Cholinesterase P06276 CHLE_HUMAN Homo sapiens 2 0.7519
Cholinesterase P06276 CHLE_HUMAN Homo sapiens 2 0.7519
Glucan 1,3-beta-glucosidase P29717 EXG1_CANAL Candida albicans 2 0.7517
Glucan 1,3-beta-glucosidase P29717 EXG1_CANAL Candida albicans 2 0.7517
Pheromone-binding protein ASP1 Q9U9J6 Q9U9J6_APIME Apis mellifera 2 0.7514
cGMP-dependent protein kinase 1 Q13976 KGP1_HUMAN Homo sapiens 2 0.7514
cGMP-dependent protein kinase 1 Q13976 KGP1_HUMAN Homo sapiens 2 0.7514
Pheromone-binding protein ASP1 Q9U9J6 Q9U9J6_APIME Apis mellifera 2 0.7514
Beta-lactoglobulin P02754 LACB_BOVIN Bos taurus 2 0.7512
Alcohol dehydrogenase 1C P00326 ADH1G_HUMAN Homo sapiens 2 0.7512
Beta-lactoglobulin P02754 LACB_BOVIN Bos taurus 2 0.7512
Alcohol dehydrogenase 1C P00326 ADH1G_HUMAN Homo sapiens 2 0.7512
Glutamate receptor 2 P19491 GRIA2_RAT Rattus norvegicus 2 0.7511
Glutamate receptor 2 P19491 GRIA2_RAT Rattus norvegicus 2 0.7511
Sulfotransferase 2A1 Q06520 ST2A1_HUMAN Homo sapiens 3 0.7511
Sulfotransferase 2A1 Q06520 ST2A1_HUMAN Homo sapiens 3 0.7511
Protoporphyrinogen oxidase, mitochondrial O24164 PPOM_TOBAC Nicotiana tabacum 2 0.7501
Protoporphyrinogen oxidase, mitochondrial O24164 PPOM_TOBAC Nicotiana tabacum 2 0.7501
Lactoperoxidase A0A452E9Y6 PERL_CAPHI Capra hircus 2 0.7500
Lactoperoxidase A0A452E9Y6 PERL_CAPHI Capra hircus 2 0.7500
Bromodomain-containing protein 4 O60885 BRD4_HUMAN Homo sapiens 3 0.7498
Bromodomain-containing protein 4 O60885 BRD4_HUMAN Homo sapiens 3 0.7498
Nuclear receptor subfamily 4immunitygroup A member 1 P22736 NR4A1_HUMAN Homo sapiens 2 0.7497
Nuclear receptor subfamily 4immunitygroup A member 1 P22736 NR4A1_HUMAN Homo sapiens 2 0.7497
Mitogen-activated protein kinase 14 Q16539 MK14_HUMAN Homo sapiens 2 0.7496
Mitogen-activated protein kinase 14 Q16539 MK14_HUMAN Homo sapiens 2 0.7496
Heat shock protein HSP 90-alpha P07900 HS90A_HUMAN Homo sapiens 2 0.7493
Putative protease I Q8A8A4 Q8A8A4_BACTN Bacteroides thetaiotaomicron 2 0.7493
Heat shock protein HSP 90-alpha P07900 HS90A_HUMAN Homo sapiens 2 0.7493
Putative protease I Q8A8A4 Q8A8A4_BACTN Bacteroides thetaiotaomicron 2 0.7493
Endoplasmin P14625 ENPL_HUMAN Homo sapiens 3 0.7491
Endoplasmin P14625 ENPL_HUMAN Homo sapiens 3 0.7491
Pheromone-binding protein ASP1 Q9U9J6 Q9U9J6_APIME Apis mellifera 2 0.7488
Pheromone-binding protein ASP1 Q9U9J6 Q9U9J6_APIME Apis mellifera 2 0.7488
Methionine aminopeptidase P0AE18 MAP1_ECOLI Escherichia coli 2 0.7486
Methionine aminopeptidase P0AE18 MAP1_ECOLI Escherichia coli 2 0.7486
Alpha-ketoglutarate-dependent dioxygenase FTO Q9C0B1 FTO_HUMAN Homo sapiens 2 0.7483
Alpha-ketoglutarate-dependent dioxygenase FTO Q9C0B1 FTO_HUMAN Homo sapiens 2 0.7483
High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A O76083 PDE9A_HUMAN Homo sapiens 3 0.7477
High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A O76083 PDE9A_HUMAN Homo sapiens 3 0.7477
Pentaerythritol tetranitrate reductase P71278 P71278_ENTCL Enterobacter cloacae 2 0.7468
Pentaerythritol tetranitrate reductase P71278 P71278_ENTCL Enterobacter cloacae 2 0.7468
Tetracycline repressor protein class D P0ACT4 TETR4_ECOLX Escherichia coli 2 0.7467
Tetracycline repressor protein class D P0ACT4 TETR4_ECOLX Escherichia coli 2 0.7467
TetR family transcriptional regulator Q58L87 Q58L87_MYCSM Mycolicibacterium smegmatis 2 0.7461
TetR family transcriptional regulator Q58L87 Q58L87_MYCSM Mycolicibacterium smegmatis 2 0.7461
Bifunctional dihydrofolate reductase-thymidylate synthase P13922 DRTS_PLAFK Plasmodium falciparum 2 0.7460
Bifunctional dihydrofolate reductase-thymidylate synthase P13922 DRTS_PLAFK Plasmodium falciparum 2 0.7460
Beta-secretase 1 P56817 BACE1_HUMAN Homo sapiens 2 0.7460
Beta-secretase 1 P56817 BACE1_HUMAN Homo sapiens 2 0.7460
Aldo-keto reductase family 1 member B1 P15121 ALDR_HUMAN Homo sapiens 2 0.7458
Aldo-keto reductase family 1 member B1 P15121 ALDR_HUMAN Homo sapiens 2 0.7458
Flavin-dependent monooxygenase Q93L51 TETX_BACT4 Bacteroides thetaiotaomicron 2 0.7456
Chitinase A Q9AMP1 Q9AMP1_VIBHA Vibrio harveyi 2 0.7456
Flavin-dependent monooxygenase Q93L51 TETX_BACT4 Bacteroides thetaiotaomicron 2 0.7456
Chitinase A Q9AMP1 Q9AMP1_VIBHA Vibrio harveyi 2 0.7456
cAMP-dependent protein kinase type II-beta regulatory subunit P12369 KAP3_RAT Rattus norvegicus 2 0.7455
cAMP-dependent protein kinase type II-beta regulatory subunit P12369 KAP3_RAT Rattus norvegicus 2 0.7455
Glucose-1-phosphate thymidylyltransferase Q9HU22 Q9HU22_PSEAE Pseudomonas aeruginosa 3 0.7449
Protein ppBat Q8A8A4 Q8A8A4_BACTN Bacteroides thetaiotaomicron VPI-5482 2 0.7449
Glucose-1-phosphate thymidylyltransferase Q9HU22 Q9HU22_PSEAE Pseudomonas aeruginosa 3 0.7449
Protein ppBat Q8A8A4 Q8A8A4_BACTN Bacteroides thetaiotaomicron VPI-5482 2 0.7449
Dihydroorotate dehydrogenase (quinone), mitochondrial Q08210 PYRD_PLAF7 Plasmodium falciparum 3 0.7448
Dihydroorotate dehydrogenase (quinone), mitochondrial Q08210 PYRD_PLAF7 Plasmodium falciparum 3 0.7448
Mitogen-activated protein kinase 14 Q16539 MK14_HUMAN Homo sapiens 2 0.7446
Mitogen-activated protein kinase 14 Q16539 MK14_HUMAN Homo sapiens 2 0.7446
Genome polyprotein O92972 POLG_HCVJ4 Hepatitis C virus genotype 1b 2 0.7446
Genome polyprotein O92972 POLG_HCVJ4 Hepatitis C virus genotype 1b 2 0.7446
Phosphotriesterase Q5KZU5 Q5KZU5_GEOKA Geobacillus kaustophilus 2 0.7445
Phosphotriesterase Q5KZU5 Q5KZU5_GEOKA Geobacillus kaustophilus 2 0.7445
Steroid Delta-isomerase P07445 SDIS_PSEPU Pseudomonas putida 3 0.7443
Steroid Delta-isomerase P07445 SDIS_PSEPU Pseudomonas putida 3 0.7443
Serine/threonine-protein kinase 24 Q9Y6E0 STK24_HUMAN Homo sapiens 3 0.7435
Serine/threonine-protein kinase 24 Q9Y6E0 STK24_HUMAN Homo sapiens 3 0.7435
Beta-secretase 1 P56817 BACE1_HUMAN Homo sapiens 2 0.7432
Beta-secretase 1 P56817 BACE1_HUMAN Homo sapiens 2 0.7432
CCA-adding enzyme O28126 CCA_ARCFU Archaeoglobus fulgidus 2 0.7431
CCA-adding enzyme O28126 CCA_ARCFU Archaeoglobus fulgidus 2 0.7431
Riboflavin synthase P0AFU8 RISA_ECOLI Escherichia coli 3 0.7425
Riboflavin synthase P0AFU8 RISA_ECOLI Escherichia coli 3 0.7425
Angiotensin-converting enzyme 2 Q9BYF1 ACE2_HUMAN Homo sapiens 2 0.7422
Angiotensin-converting enzyme 2 Q9BYF1 ACE2_HUMAN Homo sapiens 2 0.7422
Gag-Pol polyprotein P12497 POL_HV1N5 Human immunodeficiency virus type 1 group M subtype B 3 0.7419
Cyclic AMP receptor protein Q5SID7 CRP_THET8 Thermus thermophilus 2 0.7419
Cyclic AMP receptor protein Q5SID7 CRP_THET8 Thermus thermophilus 2 0.7419
Gag-Pol polyprotein P12497 POL_HV1N5 Human immunodeficiency virus type 1 group M subtype B 3 0.7419
Gag-Pol polyprotein P12497 POL_HV1N5 Human immunodeficiency virus type 1 group M subtype B 3 0.7409
Gag-Pol polyprotein P12497 POL_HV1N5 Human immunodeficiency virus type 1 group M subtype B 3 0.7409
Nuclear receptor ROR-beta P45446 RORB_RAT Rattus norvegicus 2 0.7407
Nuclear receptor ROR-beta P45446 RORB_RAT Rattus norvegicus 2 0.7407
Lactotransferrin P24627 TRFL_BOVIN Bos taurus 2 0.7406
Lactotransferrin P24627 TRFL_BOVIN Bos taurus 2 0.7406
Retinol dehydratase Q26490 Q26490_SPOFR Spodoptera frugiperda 3 0.7405
Retinol dehydratase Q26490 Q26490_SPOFR Spodoptera frugiperda 3 0.7405
Ribosyldihydronicotinamide dehydrogenase [quinone] P16083 NQO2_HUMAN Homo sapiens 2 0.7403
Ribosyldihydronicotinamide dehydrogenase [quinone] P16083 NQO2_HUMAN Homo sapiens 2 0.7403
Ceramide transfer protein Q9Y5P4 CERT_HUMAN Homo sapiens 2 0.7398
Ceramide transfer protein Q9Y5P4 CERT_HUMAN Homo sapiens 2 0.7398
Nitric oxide synthase, inducible P35228 NOS2_HUMAN Homo sapiens 2 0.7398
Nitric oxide synthase, inducible P35228 NOS2_HUMAN Homo sapiens 2 0.7398
Corticosteroid-binding globulin P08185 CBG_HUMAN Homo sapiens 3 0.7396
Corticosteroid-binding globulin P08185 CBG_HUMAN Homo sapiens 3 0.7396
Cytochrome P450 2C9 P11712 CP2C9_HUMAN Homo sapiens 2 0.7390
Cytochrome P450 2C9 P11712 CP2C9_HUMAN Homo sapiens 2 0.7390
Cyclin-dependent kinase 2 P24941 CDK2_HUMAN Homo sapiens 2 0.7387
Cyclin-dependent kinase 2 P24941 CDK2_HUMAN Homo sapiens 2 0.7387
Succinate dehydrogenase flavoprotein subunit P0AC41 SDHA_ECOLI Escherichia coli 2 0.7381
Succinate dehydrogenase flavoprotein subunit P0AC41 SDHA_ECOLI Escherichia coli 2 0.7381
Endothiapepsin P11838 CARP_CRYPA Cryphonectria parasitica 2 0.7371
Endothiapepsin P11838 CARP_CRYPA Cryphonectria parasitica 2 0.7371
3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase O33877 FABA_PSEAE Pseudomonas aeruginosa 2 0.7370
3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase O33877 FABA_PSEAE Pseudomonas aeruginosa 2 0.7370
Glycogen synthase kinase-3 beta P49841 GSK3B_HUMAN Homo sapiens 2 0.7370
Glycogen synthase kinase-3 beta P49841 GSK3B_HUMAN Homo sapiens 2 0.7370
Ribosome-inactivating protein 3 P25891 RIP3_MAIZE Zea mays 2 0.7368
Ribosome-inactivating protein 3 P25891 RIP3_MAIZE Zea mays 2 0.7368
Photosynthetic reaction center cytochrome c subunit P07173 CYCR_BLAVI Blastochloris viridis 2 0.7367
Photosynthetic reaction center cytochrome c subunit P07173 CYCR_BLAVI Blastochloris viridis 2 0.7367
Lactotransferrin P24627 TRFL_BOVIN Bos taurus 2 0.7364
Lactotransferrin P24627 TRFL_BOVIN Bos taurus 2 0.7364
ABC-type polar amino acid transport system, ATPase component Q8RCC2 Q8RCC2_CALS4 Caldanaerobacter subterraneus subsp. tengcongensis 2 0.7363
ABC-type polar amino acid transport system, ATPase component Q8RCC2 Q8RCC2_CALS4 Caldanaerobacter subterraneus subsp. tengcongensis 2 0.7363
Purine nucleoside phosphorylase DeoD-type P0ABP8 DEOD_ECOLI Escherichia coli 2 0.7361
Purine nucleoside phosphorylase DeoD-type P0ABP8 DEOD_ECOLI Escherichia coli 2 0.7361
Acetylcholinesterase P04058 ACES_TETCF Tetronarce californica 2 0.7360
Acetylcholinesterase P04058 ACES_TETCF Tetronarce californica 2 0.7360
CCA-adding enzyme O28126 CCA_ARCFU Archaeoglobus fulgidus 2 0.7357
CCA-adding enzyme O28126 CCA_ARCFU Archaeoglobus fulgidus 2 0.7357
Eugenol synthase 1 Q15GI4 EGS1_OCIBA Ocimum basilicum 3 0.7356
Eugenol synthase 1 Q15GI4 EGS1_OCIBA Ocimum basilicum 3 0.7356
Capsid protein Q9WBP8 Q9WBP8_9VIRU Adeno-associated virus - 1 2 0.7355
Prostaglandin G/H synthase 1 P05979 PGH1_SHEEP Ovis aries 2 0.7355
Protein UshA P07024 USHA_ECOLI Escherichia coli 2 0.7355
Prostaglandin G/H synthase 1 P05979 PGH1_SHEEP Ovis aries 2 0.7355
Capsid protein Q9WBP8 Q9WBP8_9VIRU Adeno-associated virus - 1 2 0.7355
Protein UshA P07024 USHA_ECOLI Escherichia coli 2 0.7355
(RS)-norcoclaurine 6-O-methyltransferase Q5C9L7 6OMT_THLFG Thalictrum flavum subsp. glaucum 3 0.7348
(RS)-norcoclaurine 6-O-methyltransferase Q5C9L7 6OMT_THLFG Thalictrum flavum subsp. glaucum 3 0.7348
Proto-oncogene tyrosine-protein kinase Src P00523 SRC_CHICK Gallus gallus 3 0.7346
Proto-oncogene tyrosine-protein kinase Src P00523 SRC_CHICK Gallus gallus 3 0.7346
Adenylate cyclase 2 A0A2U2H3Y1 A0A384LKY8_YERPE Yersinia pestis 2 0.7343
Adenylate cyclase 2 A0A2U2H3Y1 A0A384LKY8_YERPE Yersinia pestis 2 0.7343
DNA polymerase III subunit epsilon P03007 DPO3E_ECOLI Escherichia coli 2 0.7342
DNA polymerase III subunit epsilon P03007 DPO3E_ECOLI Escherichia coli 2 0.7342
Casein kinase I isoform gamma-3 Q9Y6M4 KC1G3_HUMAN Homo sapiens 3 0.7340
Casein kinase I isoform gamma-3 Q9Y6M4 KC1G3_HUMAN Homo sapiens 3 0.7340
Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial Q8N5Z0 AADAT_HUMAN Homo sapiens 2 0.7338
Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial Q8N5Z0 AADAT_HUMAN Homo sapiens 2 0.7338
Glycogen synthase kinase-3 beta P49841 GSK3B_HUMAN Homo sapiens 2 0.7337
Glycogen synthase kinase-3 beta P49841 GSK3B_HUMAN Homo sapiens 2 0.7337
Peroxidase C1A P00433 PER1A_ARMRU Armoracia rusticana 2 0.7332
Peroxidase C1A P00433 PER1A_ARMRU Armoracia rusticana 2 0.7332
Protein S100-A13 Q99584 S10AD_HUMAN Homo sapiens 2 0.7329
Protein S100-A13 Q99584 S10AD_HUMAN Homo sapiens 2 0.7329
NTPase P4 Q94M05 Q94M05_9VIRU Pseudomonas phage phi12 2 0.7328
NTPase P4 Q94M05 Q94M05_9VIRU Pseudomonas phage phi12 2 0.7328
Liver carboxylesterase 1 P23141 EST1_HUMAN Homo sapiens 2 0.7318
Liver carboxylesterase 1 P23141 EST1_HUMAN Homo sapiens 2 0.7318
Methionine aminopeptidase 1 P53582 MAP11_HUMAN Homo sapiens 2 0.7308
Methionine aminopeptidase 1 P53582 MAP11_HUMAN Homo sapiens 2 0.7308
Cytochrome P450 2D6 P10635 CP2D6_HUMAN Homo sapiens 2 0.7307
Putative cytochrome P450 Q70AS3 Q70AS3_STRPE Streptomyces peucetius 3 0.7307
Cytochrome P450 2D6 P10635 CP2D6_HUMAN Homo sapiens 2 0.7307
Putative cytochrome P450 Q70AS3 Q70AS3_STRPE Streptomyces peucetius 3 0.7307
Queuine tRNA-ribosyltransferase P28720 TGT_ZYMMO Zymomonas mobilis subsp. mobilis 2 0.7305
Queuine tRNA-ribosyltransferase P28720 TGT_ZYMMO Zymomonas mobilis subsp. mobilis 2 0.7305
High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A O76083 PDE9A_HUMAN Homo sapiens 3 0.7302
High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A O76083 PDE9A_HUMAN Homo sapiens 3 0.7302
Queuine tRNA-ribosyltransferase P28720 TGT_ZYMMO Zymomonas mobilis subsp. mobilis 2 0.7301
Queuine tRNA-ribosyltransferase P28720 TGT_ZYMMO Zymomonas mobilis subsp. mobilis 2 0.7301
Aldo-keto reductase family 1 member D1 P51857 AK1D1_HUMAN Homo sapiens 3 0.7300
Aldo-keto reductase family 1 member D1 P51857 AK1D1_HUMAN Homo sapiens 3 0.7300
Homoserine dehydrogenase P31116 DHOM_YEAST Saccharomyces cerevisiae 3 0.7294
Homoserine dehydrogenase P31116 DHOM_YEAST Saccharomyces cerevisiae 3 0.7294
4-hydroxyphenylacetate 3-monooxygenase Q8YHT7 Q8YHT7_BRUME Brucella melitensis biotype 1 2 0.7293
4-hydroxyphenylacetate 3-monooxygenase Q8YHT7 Q8YHT7_BRUME Brucella melitensis biotype 1 2 0.7293
Cyclin-dependent kinase 2 P24941 CDK2_HUMAN Homo sapiens 2 0.7292
Cyclin-dependent kinase 2 P24941 CDK2_HUMAN Homo sapiens 2 0.7292
Prostaglandin reductase 3 Q8N4Q0 PTGR3_HUMAN Homo sapiens 2 0.7290
2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate hydrolase P47229 BPHD_PARXL Paraburkholderia xenovorans 2 0.7290
2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate hydrolase P47229 BPHD_PARXL Paraburkholderia xenovorans 2 0.7290
Prostaglandin reductase 3 Q8N4Q0 PTGR3_HUMAN Homo sapiens 2 0.7290
cGMP-specific 3',5'-cyclic phosphodiesterase O76074 PDE5A_HUMAN Homo sapiens 3 0.7289
cGMP-specific 3',5'-cyclic phosphodiesterase O76074 PDE5A_HUMAN Homo sapiens 3 0.7289
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 O88703 HCN2_MOUSE Mus musculus 2 0.7287
Serine/threonine-protein kinase Chk1 O14757 CHK1_HUMAN Homo sapiens 3 0.7287
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 O88703 HCN2_MOUSE Mus musculus 2 0.7287
Tetracycline repressor protein class D P0ACT4 TETR4_ECOLX Escherichia coli 2 0.7287
Serine/threonine-protein kinase Chk1 O14757 CHK1_HUMAN Homo sapiens 3 0.7287
Tetracycline repressor protein class D P0ACT4 TETR4_ECOLX Escherichia coli 2 0.7287
Nuclear receptor subfamily 1 group I member 3 O35627 NR1I3_MOUSE Mus musculus 2 0.7286
Nuclear receptor subfamily 1 group I member 3 O35627 NR1I3_MOUSE Mus musculus 2 0.7286
Serine/threonine-protein kinase SKY1 Q03656 SKY1_YEAST Saccharomyces cerevisiae 2 0.7285
Serine/threonine-protein kinase SKY1 Q03656 SKY1_YEAST Saccharomyces cerevisiae 2 0.7285
Ephrin type-B receptor 2 P54763 EPHB2_MOUSE Mus musculus 2 0.7283
Ephrin type-B receptor 2 P54763 EPHB2_MOUSE Mus musculus 2 0.7283
Sulfotransferase 1A1 P50225 ST1A1_HUMAN Homo sapiens 2 0.7283
Sulfotransferase 1A1 P50225 ST1A1_HUMAN Homo sapiens 2 0.7283
Bifunctional epoxide hydrolase 2 P34913 HYES_HUMAN Homo sapiens 2 0.7278
Bifunctional epoxide hydrolase 2 P34913 HYES_HUMAN Homo sapiens 2 0.7278
Diamine acetyltransferase 1 P21673 SAT1_HUMAN Homo sapiens 2 0.7273
Casein kinase II subunit alpha P68400 CSK21_HUMAN Homo sapiens 2 0.7273
Diamine acetyltransferase 1 P21673 SAT1_HUMAN Homo sapiens 2 0.7273
Casein kinase II subunit alpha P68400 CSK21_HUMAN Homo sapiens 2 0.7273
Endothiapepsin P11838 CARP_CRYPA Cryphonectria parasitica 2 0.7270
Endothiapepsin P11838 CARP_CRYPA Cryphonectria parasitica 2 0.7270
Steroid 17-alpha-hydroxylase/17,20 lyase P05093 CP17A_HUMAN Homo sapiens 2 0.7269
Steroid 17-alpha-hydroxylase/17,20 lyase P05093 CP17A_HUMAN Homo sapiens 2 0.7269
Aklanonic acid methyl ester cyclase AcmA O52646 DNRD_STRGJ Streptomyces galilaeus 3 0.7264
Aklanonic acid methyl ester cyclase AcmA O52646 DNRD_STRGJ Streptomyces galilaeus 3 0.7264
2',3'-cyclic-nucleotide 3'-phosphodiesterase P16330 CN37_MOUSE Mus musculus 2 0.7262
2',3'-cyclic-nucleotide 3'-phosphodiesterase P16330 CN37_MOUSE Mus musculus 2 0.7262
2',3'-cyclic-nucleotide 3'-phosphodiesterase P16330 CN37_MOUSE Mus musculus 2 0.7261
2',3'-cyclic-nucleotide 3'-phosphodiesterase P16330 CN37_MOUSE Mus musculus 2 0.7261
Beta-secretase 1 P56817 BACE1_HUMAN Homo sapiens 2 0.7257
Beta-secretase 1 P56817 BACE1_HUMAN Homo sapiens 2 0.7257
Genome polyprotein P26663 POLG_HCVBK Hepatitis C virus genotype 1b 2 0.7255
Genome polyprotein P26663 POLG_HCVBK Hepatitis C virus genotype 1b 2 0.7255
ATP synthase subunit alpha, mitochondrial P19483 ATPA_BOVIN Bos taurus 2 0.7254
ATP synthase subunit alpha, mitochondrial P19483 ATPA_BOVIN Bos taurus 2 0.7254
Beta-glucosidase 12 B8AVF0 BGL12_ORYSI Oryza sativa subsp. indica 2 0.7253
Beta-glucosidase 12 B8AVF0 BGL12_ORYSI Oryza sativa subsp. indica 2 0.7253
Casein kinase II subunit alpha P68400 CSK21_HUMAN Homo sapiens 2 0.7253
Casein kinase II subunit alpha P68400 CSK21_HUMAN Homo sapiens 2 0.7253
cGMP-dependent protein kinase, putative A5K0N4 A5K0N4_PLAVS Plasmodium vivax 3 0.7251
cGMP-dependent protein kinase, putative A5K0N4 A5K0N4_PLAVS Plasmodium vivax 3 0.7251
Lactotransferrin P24627 TRFL_BOVIN Bos taurus 2 0.7250
Lactotransferrin P24627 TRFL_BOVIN Bos taurus 2 0.7250
Protein S100-A4 P26447 S10A4_HUMAN Homo sapiens 2 0.7249
Protein S100-A4 P26447 S10A4_HUMAN Homo sapiens 2 0.7249
Tyrosine-protein kinase Lck P06239 LCK_HUMAN Homo sapiens 3 0.7249
Tyrosine-protein kinase Lck P06239 LCK_HUMAN Homo sapiens 3 0.7249
cGMP-dependent protein kinase 1 Q13976 KGP1_HUMAN Homo sapiens 2 0.7248
cGMP-dependent protein kinase 1 Q13976 KGP1_HUMAN Homo sapiens 2 0.7248
N-terminal acetyltransferase A complex subunit NAT1 P12945 NAT1_YEAST Saccharomyces cerevisiae 2 0.7247
N-terminal acetyltransferase A complex subunit NAT1 P12945 NAT1_YEAST Saccharomyces cerevisiae 2 0.7247
Serine/threonine-protein kinase Chk1 O14757 CHK1_HUMAN Homo sapiens 3 0.7245
Serine/threonine-protein kinase Chk1 O14757 CHK1_HUMAN Homo sapiens 3 0.7245
Dihydroorotate dehydrogenase (quinone), mitochondrial Q02127 PYRD_HUMAN Homo sapiens 3 0.7230
Basic phospholipase A2 VRV-PL-VIIIa P59071 PA2B8_DABRR Daboia russelii 2 0.7230
Dihydroorotate dehydrogenase (quinone), mitochondrial Q02127 PYRD_HUMAN Homo sapiens 3 0.7230
Basic phospholipase A2 VRV-PL-VIIIa P59071 PA2B8_DABRR Daboia russelii 2 0.7230
Thymidylate synthase P45352 TYSY_RAT Rattus norvegicus 2 0.7228
Thymidylate synthase P45352 TYSY_RAT Rattus norvegicus 2 0.7228
ATP-dependent molecular chaperone HSP82 P02829 HSP82_YEAST Saccharomyces cerevisiae 2 0.7227
ATP-dependent molecular chaperone HSP82 P02829 HSP82_YEAST Saccharomyces cerevisiae 2 0.7227
Endothiapepsin P11838 CARP_CRYPA Cryphonectria parasitica 2 0.7226
Endothiapepsin P11838 CARP_CRYPA Cryphonectria parasitica 2 0.7226
Fibroblast growth factor receptor 2 P21802 FGFR2_HUMAN Homo sapiens 2 0.7225
L-lactate dehydrogenase A chain P13491 LDHA_RABIT Oryctolagus cuniculus 2 0.7225
Fibroblast growth factor receptor 2 P21802 FGFR2_HUMAN Homo sapiens 2 0.7225
L-lactate dehydrogenase A chain P13491 LDHA_RABIT Oryctolagus cuniculus 2 0.7225
Alpha/beta hydrolase fold A5VAT9 A5VAT9_SPHWW Sphingomonas wittichii 2 0.7222
Alpha/beta hydrolase fold A5VAT9 A5VAT9_SPHWW Sphingomonas wittichii 2 0.7222
DNA-directed DNA polymerase Q38087 DPOL_BPR69 Escherichia phage RB69 2 0.7219
DNA-directed DNA polymerase Q38087 DPOL_BPR69 Escherichia phage RB69 2 0.7219
2',3'-cyclic-nucleotide 3'-phosphodiesterase P16330 CN37_MOUSE Mus musculus 2 0.7216
2',3'-cyclic-nucleotide 3'-phosphodiesterase P16330 CN37_MOUSE Mus musculus 2 0.7216
D-alanyl-D-alanine carboxypeptidase P15555 DAC_STRSR Streptomyces sp 2 0.7215
D-alanyl-D-alanine carboxypeptidase P15555 DAC_STRSR Streptomyces sp 2 0.7215
Transcriptional regulator, PadR-like family A2RI36 A2RI36_LACLM Lactococcus lactis subsp. cremoris 2 0.7214
Transcriptional regulator, PadR-like family A2RI36 A2RI36_LACLM Lactococcus lactis subsp. cremoris 2 0.7214
Acetylcholinesterase P21836 ACES_MOUSE Mus musculus 2 0.7212
Acetylcholinesterase P21836 ACES_MOUSE Mus musculus 2 0.7212
Catalase-peroxidase Q3JNW6 KATG_BURP1 Burkholderia pseudomallei 2 0.7211
Catalase-peroxidase Q3JNW6 KATG_BURP1 Burkholderia pseudomallei 2 0.7211
Carbonic anhydrase 4 Q64444 CAH4_MOUSE Mus musculus 2 0.7208
Carbonic anhydrase 4 Q64444 CAH4_MOUSE Mus musculus 2 0.7208
Biotin carboxylase P43873 ACCC_HAEIN Haemophilus influenzae 2 0.7207
Biotin carboxylase P43873 ACCC_HAEIN Haemophilus influenzae 2 0.7207
Urokinase-type plasminogen activator P00749 UROK_HUMAN Homo sapiens 2 0.7205
Urokinase-type plasminogen activator P00749 UROK_HUMAN Homo sapiens 2 0.7205
High affinity 3',5'-cyclic-AMP phosphodiesterase 7A Q13946 PDE7A_HUMAN Homo sapiens 3 0.7204
High affinity 3',5'-cyclic-AMP phosphodiesterase 7A Q13946 PDE7A_HUMAN Homo sapiens 3 0.7204
Casein kinase II subunit alpha P68400 CSK21_HUMAN Homo sapiens 2 0.7200
Casein kinase II subunit alpha P68400 CSK21_HUMAN Homo sapiens 2 0.7200
Pyridoxal kinase O00764 PDXK_HUMAN Homo sapiens 2 0.7198
Pyridoxal kinase O00764 PDXK_HUMAN Homo sapiens 2 0.7198
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase Q3JRA0 ISPF_BURP1 Burkholderia pseudomallei 3 0.7196
Odorant binding protein ASP1 Q8WRW5 Q8WRW5_APIME Apis mellifera 2 0.7196
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase Q3JRA0 ISPF_BURP1 Burkholderia pseudomallei 3 0.7196
Odorant binding protein ASP1 Q8WRW5 Q8WRW5_APIME Apis mellifera 2 0.7196
Fatty acid-binding protein, intestinal P12104 FABPI_HUMAN Homo sapiens 2 0.7191
Fatty acid-binding protein, intestinal P12104 FABPI_HUMAN Homo sapiens 2 0.7191
Cytochrome P450 2D6 P10635 CP2D6_HUMAN Homo sapiens 2 0.7190
Cytochrome P450 2D6 P10635 CP2D6_HUMAN Homo sapiens 2 0.7190
Nicotinamide phosphoribosyltransferase P43490 NAMPT_HUMAN Homo sapiens 2 0.7189
Nicotinamide phosphoribosyltransferase P43490 NAMPT_HUMAN Homo sapiens 2 0.7189
Nucleoside diphosphate kinase A5J299 A5J299_PENVA Penaeus vannamei 2 0.7188
Aminoglycoside 3'-phosphotransferase AphA1-IAB B0VD92 B0VD92_ACIBY Acinetobacter baumannii 3 0.7188
Aminoglycoside 3'-phosphotransferase AphA1-IAB B0VD92 B0VD92_ACIBY Acinetobacter baumannii 3 0.7188
Nucleoside diphosphate kinase A5J299 A5J299_PENVA Penaeus vannamei 2 0.7188
Queuine tRNA-ribosyltransferase P28720 TGT_ZYMMO Zymomonas mobilis subsp. mobilis 2 0.7187
Queuine tRNA-ribosyltransferase P28720 TGT_ZYMMO Zymomonas mobilis subsp. mobilis 2 0.7187
Non-receptor tyrosine-protein kinase TYK2 P29597 TYK2_HUMAN Homo sapiens 2 0.7184
Non-receptor tyrosine-protein kinase TYK2 P29597 TYK2_HUMAN Homo sapiens 2 0.7184
2',3'-cyclic-nucleotide 3'-phosphodiesterase P16330 CN37_MOUSE Mus musculus 2 0.7180
2',3'-cyclic-nucleotide 3'-phosphodiesterase P16330 CN37_MOUSE Mus musculus 2 0.7180
DNA ligase P43813 DNLJ_HAEIN Haemophilus influenzae 2 0.7179
DNA ligase P43813 DNLJ_HAEIN Haemophilus influenzae 2 0.7179
Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 Q9Y3Z3 SAMH1_HUMAN Homo sapiens 2 0.7177
Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 Q9Y3Z3 SAMH1_HUMAN Homo sapiens 2 0.7177
Carbonic anhydrase 2 P00918 CAH2_HUMAN Homo sapiens 2 0.7176
Carbonic anhydrase 2 P00918 CAH2_HUMAN Homo sapiens 2 0.7176
Enoyl-ACP reductase Q9BH77 Q9BH77_PLAFA Plasmodium falciparum 2 0.7173
Enoyl-ACP reductase Q9BH77 Q9BH77_PLAFA Plasmodium falciparum 2 0.7173
Tetracycline repressor protein class B from transposon Tn10 P04483 TETR2_ECOLX Escherichia coli 2 0.7172
Tetracycline repressor protein class B from transposon Tn10 P04483 TETR2_ECOLX Escherichia coli 2 0.7172
Lactoperoxidase P80025 PERL_BOVIN Bos taurus 2 0.7171
Lactoperoxidase P80025 PERL_BOVIN Bos taurus 2 0.7171
Acyl-coenzyme A synthetase ACSM2A, mitochondrial Q08AH3 ACS2A_HUMAN Homo sapiens 2 0.7166
Acyl-coenzyme A synthetase ACSM2A, mitochondrial Q08AH3 ACS2A_HUMAN Homo sapiens 2 0.7166
5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase P0AF12 MTNN_ECOLI Escherichia coli 2 0.7161
5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase P0AF12 MTNN_ECOLI Escherichia coli 2 0.7161
Single-stranded-DNA-specific exonuclease RecJ D0EM60 D0EM60_DEIRD Deinococcus radiodurans 2 0.7157
NADPH-dependent oxidoreductase 2-alkenal reductase Q39172 AER_ARATH Arabidopsis thaliana 2 0.7157
Single-stranded-DNA-specific exonuclease RecJ D0EM60 D0EM60_DEIRD Deinococcus radiodurans 2 0.7157
NADPH-dependent oxidoreductase 2-alkenal reductase Q39172 AER_ARATH Arabidopsis thaliana 2 0.7157
Ribosyldihydronicotinamide dehydrogenase [quinone] P16083 NQO2_HUMAN Homo sapiens 2 0.7156
Ribosyldihydronicotinamide dehydrogenase [quinone] P16083 NQO2_HUMAN Homo sapiens 2 0.7156
Purine nucleoside phosphorylase DeoD-type Q5EEL8 DEOD_BACCE Bacillus cereus 2 0.7156
Purine nucleoside phosphorylase DeoD-type Q5EEL8 DEOD_BACCE Bacillus cereus 2 0.7156
ADP compounds hydrolase NudE P45799 NUDE_ECOLI Escherichia coli 2 0.7155
ADP compounds hydrolase NudE P45799 NUDE_ECOLI Escherichia coli 2 0.7155
EbrA repressor Q79SH7 Q79SH7_STRLI Streptomyces lividans 2 0.7154
EbrA repressor Q79SH7 Q79SH7_STRLI Streptomyces lividans 2 0.7154
Androgen receptor P10275 ANDR_HUMAN Homo sapiens 2 0.7153
Proline iminopeptidase O32449 PIP_SERMA Serratia marcescens 2 0.7153
Androgen receptor P10275 ANDR_HUMAN Homo sapiens 2 0.7153
Proline iminopeptidase O32449 PIP_SERMA Serratia marcescens 2 0.7153
Disintegrin and metalloproteinase domain-containing protein 17 P78536 ADA17_HUMAN Homo sapiens 2 0.7152
Disintegrin and metalloproteinase domain-containing protein 17 P78536 ADA17_HUMAN Homo sapiens 2 0.7152
Queuine tRNA-ribosyltransferase P28720 TGT_ZYMMO Zymomonas mobilis subsp. mobilis 2 0.7149
Queuine tRNA-ribosyltransferase P28720 TGT_ZYMMO Zymomonas mobilis subsp. mobilis 2 0.7149
F420-dependent NADP reductase O29370 FNO_ARCFU Archaeoglobus fulgidus 3 0.7148
Tetracycline repressor protein class D P0ACT4 TETR4_ECOLX Escherichia coli 2 0.7148
F420-dependent NADP reductase O29370 FNO_ARCFU Archaeoglobus fulgidus 3 0.7148
Tetracycline repressor protein class D P0ACT4 TETR4_ECOLX Escherichia coli 2 0.7148
Stromelysin-1 P08254 MMP3_HUMAN Homo sapiens 2 0.7147
Stromelysin-1 P08254 MMP3_HUMAN Homo sapiens 2 0.7147
Enoyl-ACP reductase Q9BH77 Q9BH77_PLAFA Plasmodium falciparum 2 0.7145
Enoyl-ACP reductase Q9BH77 Q9BH77_PLAFA Plasmodium falciparum 2 0.7145
Epoxide hydrolase Q41415 Q41415_SOLTU Solanum tuberosum 2 0.7144
Epoxide hydrolase Q41415 Q41415_SOLTU Solanum tuberosum 2 0.7144
Ketimine reductase mu-crystallin O54983 CRYM_MOUSE Mus musculus 2 0.7140
Ketimine reductase mu-crystallin O54983 CRYM_MOUSE Mus musculus 2 0.7140
Biphenyl-2,3-diol 1,2-dioxygenase P17297 BPHC_PSES1 Pseudomonas sp 2 0.7133
Biphenyl-2,3-diol 1,2-dioxygenase P17297 BPHC_PSES1 Pseudomonas sp 2 0.7133
Three-prime repair exonuclease 1 Q91XB0 TREX1_MOUSE Mus musculus 2 0.7132
Ribosyldihydronicotinamide dehydrogenase [quinone] P16083 NQO2_HUMAN Homo sapiens 2 0.7132
Ribosyldihydronicotinamide dehydrogenase [quinone] P16083 NQO2_HUMAN Homo sapiens 2 0.7132
Three-prime repair exonuclease 1 Q91XB0 TREX1_MOUSE Mus musculus 2 0.7132
Thymidylate kinase Q9HZN8 KTHY_PSEAE Pseudomonas aeruginosa 3 0.7124
Thymidylate kinase Q9HZN8 KTHY_PSEAE Pseudomonas aeruginosa 3 0.7124
Mitogen-activated protein kinase 1 P28482 MK01_HUMAN Homo sapiens 2 0.7122
Mitogen-activated protein kinase 1 P28482 MK01_HUMAN Homo sapiens 2 0.7122
Endothiapepsin P11838 CARP_CRYPA Cryphonectria parasitica 2 0.7122
Endothiapepsin P11838 CARP_CRYPA Cryphonectria parasitica 2 0.7122
Myosin heavy chain kinase A P42527 MHCKA_DICDI Dictyostelium discoideum 2 0.7121
Myosin heavy chain kinase A P42527 MHCKA_DICDI Dictyostelium discoideum 2 0.7121
Purine nucleoside phosphorylase DeoD-type Q5EEL8 DEOD_BACCE Bacillus cereus 2 0.7120
Collagenase 3 P45452 MMP13_HUMAN Homo sapiens 3 0.7120
Beta-2 adrenergic receptor P07550 ADRB2_HUMAN Homo sapiens 2 0.7120
Purine nucleoside phosphorylase DeoD-type Q5EEL8 DEOD_BACCE Bacillus cereus 2 0.7120
Collagenase 3 P45452 MMP13_HUMAN Homo sapiens 3 0.7120
Beta-2 adrenergic receptor P07550 ADRB2_HUMAN Homo sapiens 2 0.7120
Sex hormone-binding globulin P04278 SHBG_HUMAN Homo sapiens 2 0.7118
L-lactate dehydrogenase A chain P04642 LDHA_RAT Rattus norvegicus 2 0.7118
Serine/threonine-protein kinase toxin HipA P23874 HIPA_ECOLI Escherichia coli 2 0.7118
L-lactate dehydrogenase A chain P04642 LDHA_RAT Rattus norvegicus 2 0.7118
Sex hormone-binding globulin P04278 SHBG_HUMAN Homo sapiens 2 0.7118
Serine/threonine-protein kinase toxin HipA P23874 HIPA_ECOLI Escherichia coli 2 0.7118
Tetracycline repressor protein class D P0ACT4 TETR4_ECOLX Escherichia coli 2 0.7116
Tetracycline repressor protein class D P0ACT4 TETR4_ECOLX Escherichia coli 2 0.7116
Fibroblast growth factor receptor 2 P21802 FGFR2_HUMAN Homo sapiens 2 0.7114
Fibroblast growth factor receptor 2 P21802 FGFR2_HUMAN Homo sapiens 2 0.7114
Albumin P02768 ALBU_HUMAN Homo sapiens 3 0.7113
Albumin P02768 ALBU_HUMAN Homo sapiens 3 0.7113
Metallophosphoesterase A3DJ38 A3DJ38_HUNT2 Clostridium thermocellum 2 0.7110
Metallophosphoesterase A3DJ38 A3DJ38_HUNT2 Clostridium thermocellum 2 0.7110
Tyrosine-protein kinase JAK2 O60674 JAK2_HUMAN Homo sapiens 3 0.7105
Tyrosine-protein kinase JAK2 O60674 JAK2_HUMAN Homo sapiens 3 0.7105
Ribosyldihydronicotinamide dehydrogenase [quinone] P16083 NQO2_HUMAN Homo sapiens 2 0.7104
cGMP-inhibited 3',5'-cyclic phosphodiesterase 3B Q13370 PDE3B_HUMAN Homo sapiens 3 0.7104
cGMP-inhibited 3',5'-cyclic phosphodiesterase 3B Q13370 PDE3B_HUMAN Homo sapiens 3 0.7104
Ribosyldihydronicotinamide dehydrogenase [quinone] P16083 NQO2_HUMAN Homo sapiens 2 0.7104
Transthyretin P02767 TTHY_RAT Rattus norvegicus 2 0.7103
Cyclic nucleotide-gated potassium channel mll3241 Q98GN8 CNGK1_RHILO Mesorhizobium japonicum) 2 0.7103
Transthyretin P02767 TTHY_RAT Rattus norvegicus 2 0.7103
Cyclic nucleotide-gated potassium channel mll3241 Q98GN8 CNGK1_RHILO Mesorhizobium japonicum) 2 0.7103
Prostaglandin G/H synthase 2 Q05769 PGH2_MOUSE Mus musculus 2 0.7102
Prostaglandin G/H synthase 2 Q05769 PGH2_MOUSE Mus musculus 2 0.7102
Purine nucleoside phosphorylase DeoD-type O34925 DEOD_BACSU Bacillus subtilis 2 0.7101
Purine nucleoside phosphorylase DeoD-type O34925 DEOD_BACSU Bacillus subtilis 2 0.7101
Kinesin-like protein KIF11 P52732 KIF11_HUMAN Homo sapiens 2 0.7100
Kinesin-like protein KIF11 P52732 KIF11_HUMAN Homo sapiens 2 0.7100
4,5:9,10-diseco-3-hydroxy-5,9,17-trioxoandrosta-1(10),2-diene-4-oate hydrolase P9WNH5 HSAD_MYCTU Mycobacterium tuberculosis 2 0.7094
4,5:9,10-diseco-3-hydroxy-5,9,17-trioxoandrosta-1(10),2-diene-4-oate hydrolase P9WNH5 HSAD_MYCTU Mycobacterium tuberculosis 2 0.7094
Nucleoside diphosphate kinase Q5UQL3 NDK_MIMIV Acanthamoeba polyphaga mimivirus 2 0.7089
Nucleoside diphosphate kinase Q5UQL3 NDK_MIMIV Acanthamoeba polyphaga mimivirus 2 0.7089
Type IV / VI secretion system DotU domain-containing protein Q9KN50 Q9KN50_VIBCH Vibrio cholerae serotype O1 2 0.7084
Cytosolic purine 5'-nucleotidase P49902 5NTC_HUMAN Homo sapiens 2 0.7084
Type IV / VI secretion system DotU domain-containing protein Q9KN50 Q9KN50_VIBCH Vibrio cholerae serotype O1 2 0.7084
Cytosolic purine 5'-nucleotidase P49902 5NTC_HUMAN Homo sapiens 2 0.7084
NADH:flavin oxidoreductase Sye1 Q8EEC8 Q8EEC8_SHEON Shewanella oneidensis 2 0.7082
NADH:flavin oxidoreductase Sye1 Q8EEC8 Q8EEC8_SHEON Shewanella oneidensis 2 0.7082
Carminomycin 4-O-methyltransferase DnrK Q06528 DNRK_STRPE Streptomyces peucetius 2 0.7077
Non-receptor tyrosine-protein kinase TYK2 P29597 TYK2_HUMAN Homo sapiens 2 0.7077
Carminomycin 4-O-methyltransferase DnrK Q06528 DNRK_STRPE Streptomyces peucetius 2 0.7077
Non-receptor tyrosine-protein kinase TYK2 P29597 TYK2_HUMAN Homo sapiens 2 0.7077
BMP-2-inducible protein kinase Q9NSY1 BMP2K_HUMAN Homo sapiens 2 0.7075
Ribosyldihydronicotinamide dehydrogenase [quinone] P16083 NQO2_HUMAN Homo sapiens 2 0.7075
BMP-2-inducible protein kinase Q9NSY1 BMP2K_HUMAN Homo sapiens 2 0.7075
Ribosyldihydronicotinamide dehydrogenase [quinone] P16083 NQO2_HUMAN Homo sapiens 2 0.7075
Aminopeptidase N P15145 AMPN_PIG Sus scrofa 2 0.7074
Aminopeptidase N P15145 AMPN_PIG Sus scrofa 2 0.7074
D-aminoacyl-tRNA deacylase Q8IIS0 DTD_PLAF7 Plasmodium falciparum 2 0.7072
D-aminoacyl-tRNA deacylase Q8IIS0 DTD_PLAF7 Plasmodium falciparum 2 0.7072
Sex hormone-binding globulin P04278 SHBG_HUMAN Homo sapiens 3 0.7069
Sex hormone-binding globulin P04278 SHBG_HUMAN Homo sapiens 3 0.7069
Ribosyldihydronicotinamide dehydrogenase [quinone] P16083 NQO2_HUMAN Homo sapiens 2 0.7064
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 Q9Y3Q4 HCN4_HUMAN Homo sapiens 2 0.7064
Ribosyldihydronicotinamide dehydrogenase [quinone] P16083 NQO2_HUMAN Homo sapiens 2 0.7064
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 Q9Y3Q4 HCN4_HUMAN Homo sapiens 2 0.7064
Gag-Pol polyprotein P03366 POL_HV1B1 Human immunodeficiency virus type 1 group M subtype B 3 0.7060
Gag-Pol polyprotein P03366 POL_HV1B1 Human immunodeficiency virus type 1 group M subtype B 3 0.7060
Protein claret segregational P20480 NCD_DROME Drosophila melanogaster 2 0.7059
Protein claret segregational P20480 NCD_DROME Drosophila melanogaster 2 0.7059
Pentalenic acid synthase Q825I8 CYP28_STRAW Streptomyces avermitilis 2 0.7058
Pentalenic acid synthase Q825I8 CYP28_STRAW Streptomyces avermitilis 2 0.7058
Purine nucleoside phosphorylase P00491 PNPH_HUMAN Homo sapiens 2 0.7056
Purine nucleoside phosphorylase P00491 PNPH_HUMAN Homo sapiens 2 0.7056
Tetracycline repressor protein class D P0ACT4 TETR4_ECOLX Escherichia coli 2 0.7052
Tetracycline repressor protein class D P0ACT4 TETR4_ECOLX Escherichia coli 2 0.7052
Transthyretin P02767 TTHY_RAT Rattus norvegicus 2 0.7051
Transthyretin P02767 TTHY_RAT Rattus norvegicus 2 0.7051
Phospholipase A2, membrane associated P14555 PA2GA_HUMAN Homo sapiens 2 0.7049
Phospholipase A2, membrane associated P14555 PA2GA_HUMAN Homo sapiens 2 0.7049
1-deoxy-D-xylulose 5-phosphate reductoisomerase P45568 DXR_ECOLI Escherichia coli 2 0.7047
1-deoxy-D-xylulose 5-phosphate reductoisomerase P45568 DXR_ECOLI Escherichia coli 2 0.7047
Purine nucleoside phosphorylase DeoD-type P0ABP9 DEOD_ECO57 Escherichia coli O157:H7 2 0.7046
Purine nucleoside phosphorylase DeoD-type P0ABP9 DEOD_ECO57 Escherichia coli O157:H7 2 0.7046
Proline--tRNA ligase Q8I5R7 SYP_PLAF7 Plasmodium falciparum 2 0.7042
Proline--tRNA ligase Q8I5R7 SYP_PLAF7 Plasmodium falciparum 2 0.7042
Inosine-5'-monophosphate dehydrogenase P50097 IMDH_TRIFO Tritrichomonas foetus 2 0.7037
Inosine-5'-monophosphate dehydrogenase P50097 IMDH_TRIFO Tritrichomonas foetus 2 0.7037
11-beta-hydroxysteroid dehydrogenase 1 P28845 DHI1_HUMAN Homo sapiens 2 0.7036
11-beta-hydroxysteroid dehydrogenase 1 P28845 DHI1_HUMAN Homo sapiens 2 0.7036
Heat shock protein HSP 90-alpha P07900 HS90A_HUMAN Homo sapiens 2 0.7029
Heat shock protein HSP 90-alpha P07900 HS90A_HUMAN Homo sapiens 2 0.7029
Tetracycline repressor protein class D P0ACT4 TETR4_ECOLX Escherichia coli 2 0.7027
Tetracycline repressor protein class D P0ACT4 TETR4_ECOLX Escherichia coli 2 0.7027
Stromelysin-1 P08254 MMP3_HUMAN Homo sapiens 3 0.7026
Stromelysin-1 P08254 MMP3_HUMAN Homo sapiens 3 0.7026
Cyclin-dependent kinase 2 P24941 CDK2_HUMAN Homo sapiens 2 0.7025
Cyclin-dependent kinase 2 P24941 CDK2_HUMAN Homo sapiens 2 0.7025
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A Q9Y233 PDE10_HUMAN Homo sapiens 3 0.7024
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A Q9Y233 PDE10_HUMAN Homo sapiens 3 0.7024
Stromelysin-1 P08254 MMP3_HUMAN Homo sapiens 2 0.7020
Stromelysin-1 P08254 MMP3_HUMAN Homo sapiens 2 0.7020
4-diphosphocytidyl-2-C-methyl-D-erythritol kinase O67060 ISPE_AQUAE Aquifex aeolicus 2 0.7019
4-diphosphocytidyl-2-C-methyl-D-erythritol kinase O67060 ISPE_AQUAE Aquifex aeolicus 2 0.7019
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform P48736 PK3CG_HUMAN Homo sapiens 3 0.7019
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform P48736 PK3CG_HUMAN Homo sapiens 3 0.7019
NADPH dehydrogenase 1 Q02899 OYE1_SACPS Saccharomyces pastorianus 2 0.7010
NADPH dehydrogenase 1 Q02899 OYE1_SACPS Saccharomyces pastorianus 2 0.7010
Albumin P02768 ALBU_HUMAN Homo sapiens 2 0.7008
Stimulator of interferon genes protein Q86WV6 STING_HUMAN Homo sapiens 2 0.7008
Queuine tRNA-ribosyltransferase P28720 TGT_ZYMMO Zymomonas mobilis subsp. mobilis 2 0.7008
Albumin P02768 ALBU_HUMAN Homo sapiens 2 0.7008
Stimulator of interferon genes protein Q86WV6 STING_HUMAN Homo sapiens 2 0.7008
Queuine tRNA-ribosyltransferase P28720 TGT_ZYMMO Zymomonas mobilis subsp. mobilis 2 0.7008
Carbonic anhydrase 2 P00918 CAH2_HUMAN Homo sapiens 2 0.7006
Carbonic anhydrase 2 P00918 CAH2_HUMAN Homo sapiens 2 0.7006
Calmodulin-1 P0DP29 CALM1_RAT Rattus norvegicus 2 0.7005
Calmodulin-1 P0DP29 CALM1_RAT Rattus norvegicus 2 0.7005
cAMP-dependent protein kinase type I-alpha regulatory subunit P00514 KAP0_BOVIN Bos taurus 2 0.7004
cAMP-dependent protein kinase type I-alpha regulatory subunit P00514 KAP0_BOVIN Bos taurus 2 0.7004
2-phospho-L-lactate transferase Q8PVT6 COFD_METMA Methanosarcina mazei 2 0.7003
Genome polyprotein O92972 POLG_HCVJ4 Hepatitis C virus genotype 1b 3 0.7003
2-phospho-L-lactate transferase Q8PVT6 COFD_METMA Methanosarcina mazei 2 0.7003
Genome polyprotein O92972 POLG_HCVJ4 Hepatitis C virus genotype 1b 3 0.7003

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