4'-O-geranylisoliquiritigenin - Compound Card

4'-O-geranylisoliquiritigenin

Select a section from the left sidebar

4'-O-geranylisoliquiritigenin

Structure
Zoomed Structure
  • Family: Plantae - Leguminosae/Fabaceae
  • Kingdom: Plantae
  • Class: Flavonoid
    • Subclass: Chalcone
Canonical Smiles C/C(=C\COc1ccc(c(c1)O)C(=O)/C=C/c1ccc(cc1)O)/CCC=C(C)C
InChI InChI=1S/C25H28O4/c1-18(2)5-4-6-19(3)15-16-29-22-12-13-23(25(28)17-22)24(27)14-9-20-7-10-21(26)11-8-20/h5,7-15,17,26,28H,4,6,16H2,1-3H3/b14-9+,19-15+
InChIKey YGNHPWQWWZLUBY-UHGDPLQBSA-N
Formula C25H28O4
HBA 4
HBD 2
MW 392.5
Rotatable Bonds 9
TPSA 66.76
LogP 6.07
Number Rings 2
Number Aromatic Rings 2
Heavy Atom Count 29
Formal Charge 0
Fraction CSP3 0.24
Exact Mass 392.2
Number of Lipinski Rule Violations 1
# Species Family Kingdom NCBI Taxonomy ID
1 Millettia usaramensis usaramensis Leguminosae/Fabaceae Plantae 53625
2 Millettia usaramensis usaramensis Leguminosae/Fabaceae Plantae 53625

Showing of synonyms

  • Yenesew A, Derese S, et al. (2003). Anti-plasmodial activities and X-ray crystal structures of rotenoids from Millettia usaramensis subspecies usaramensis.. Phytochemistry,2003,64(3),773-779. [View] [PubMed]
  • Yenesew A, Midiwo JO, et al. (1998). Rotenoids, isoflavones and chalcones from the stem bark of Millettia usaramensis subspecies usaramensis. Phytochemistry,1998,47(2),295-300. [View] [PubMed]
Pubchem: 10318361
Nmrshiftdb2: 70057479

No compound-protein relationship available.

Structure

SMILES: c1ccccc1C(=O)C=Cc2ccccc2

Level: 1

Mol. Weight: 392.5 g/mol

Structure

SMILES: c1ccccc1

Level: 0

Mol. Weight: 392.5 g/mol

Anti-plasmodial

Absorption

Caco-2 (logPapp)
-4.63
Human Oral Bioavailability 20%
Bioavailable
Human Intestinal Absorption
Absorbed
Madin-Darby Canine Kidney
-4.69
Human Oral Bioavailability 50%
Bioavailable
P-Glycoprotein Inhibitor
Non-Inhibitor
P-Glycoprotein Substrate
Non-Substrate
Skin Permeability
-2.08

Distribution

Blood-Brain Barrier (CNS)
-
Blood-Brain Barrier
Penetrable
Fraction Unbound (Human)
1.22
Plasma Protein Binding
69.5
Steady State Volume of Distribution
-

Metabolism

Breast Cancer Resistance Protein
Inhibitor
CYP 1A2 Inhibitor
Inhibitor
CYP 1A2 Substrate
Non-Substrate
CYP 2C19 Inhibitor
Inhibitor
CYP 2C19 Substrate
Substrate
CYP 2C9 Inhibitor
Inhibitor
CYP 2C9 Substrate
Substrate
CYP 2D6 Inhibitor
Inhibitor
CYP 2D6 Substrate
Substrate
CYP 3A4 Inhibitor
Inhibitor
CYP 3A4 Substrate
Non-Substrate
OATP1B1
Inhibitor
OATP1B3
Non-Inhibitor

Excretion

Clearance
1.1
Organic Cation Transporter 2
Non-Inhibitor
Half-Life of Drug
-

Toxicity

AMES Mutagenesis
Safe
Avian
Safe
Bee
Toxic
Bioconcentration Factor
1.1
Biodegradation
Safe
Carcinogenesis
Safe
Crustacean
Toxic
Liver Injury I (DILI)
Safe
Eye Corrosion
Safe
Eye Irritation
Safe
Maximum Tolerated Dose
0.99
Liver Injury II
Toxic
hERG Blockers
Safe
Daphnia Maga
7.18
Micronucleos
Toxic
NR-AhR
Safe
NR-AR
Safe
NR-AR-LBD
Safe
NR-Aromatase
Safe
NR-ER
Toxic
NR-ER-LBD
Safe
NR-GR
Toxic
NR-PPAR-gamma
Safe
NR-TR
Toxic
T. Pyriformis
-6.08
Rat (Acute)
1.86
Rat (Chronic Oral)
2.62
Fathead Minnow
5.73
Respiratory Disease
Toxic
Skin Sensitisation
Toxic
SR-ARE
Toxic
SR-ATAD5
Safe
SR-HSE
Safe
SR-MMP
Toxic
SR-p53
Safe

General Properties

Boiling Point
468.23
Hydration Free Energy
-5.88
Log(D) at pH=7.4
4.86
Log(P)
7.07
Log S
-7.17
Log(Vapor Pressure)
-8.22
Melting Point
126.29
pKa Acid
9.74
pKa Basic
6.24
Protein Name UniProt ID Entry Name Species #Pharmacophore Points Probability (0.7 ≤ Tversky Score ≤ 1.0)
Mycocyclosin synthase P9WPP7 CP121_MYCTU Mycobacterium tuberculosis 3 0.9477
Mycocyclosin synthase P9WPP7 CP121_MYCTU Mycobacterium tuberculosis 3 0.9477
Histone deacetylase 4 P56524 HDAC4_HUMAN Homo sapiens 3 0.9459
Histone deacetylase 4 P56524 HDAC4_HUMAN Homo sapiens 3 0.9459
Stromelysin-1 P08254 MMP3_HUMAN Homo sapiens 3 0.9454
Stromelysin-1 P08254 MMP3_HUMAN Homo sapiens 3 0.9454
Neocarzinostatin P0A3R9 NCZS_STRCZ Streptomyces carzinostaticus 3 0.9451
Neocarzinostatin P0A3R9 NCZS_STRCZ Streptomyces carzinostaticus 3 0.9451
Heat shock protein HSP 90-alpha P07900 HS90A_HUMAN Homo sapiens 3 0.9395
Heat shock protein HSP 90-alpha P07900 HS90A_HUMAN Homo sapiens 3 0.9395
Dihydrofolate reductase P00378 DYR_CHICK Gallus gallus 3 0.9341
Dihydrofolate reductase P00378 DYR_CHICK Gallus gallus 3 0.9341
Aldo-keto reductase family 1 member D1 P51857 AK1D1_HUMAN Homo sapiens 3 0.9321
Aldo-keto reductase family 1 member D1 P51857 AK1D1_HUMAN Homo sapiens 3 0.9321
Pentaerythritol tetranitrate reductase P71278 P71278_ENTCL Enterobacter cloacae 3 0.9309
Pentaerythritol tetranitrate reductase P71278 P71278_ENTCL Enterobacter cloacae 3 0.9309
Prothrombin P00734 THRB_HUMAN Homo sapiens 3 0.9269
Prothrombin P00734 THRB_HUMAN Homo sapiens 3 0.9269
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform P48736 PK3CG_HUMAN Homo sapiens 3 0.9260
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform P48736 PK3CG_HUMAN Homo sapiens 3 0.9260
HTH-type transcriptional repressor PurR P0ACP7 PURR_ECOLI Escherichia coli 3 0.9255
HTH-type transcriptional repressor PurR P0ACP7 PURR_ECOLI Escherichia coli 3 0.9255
Retinol-binding protein 1 P02696 RET1_RAT Rattus norvegicus 3 0.9240
Retinol-binding protein 1 P02696 RET1_RAT Rattus norvegicus 3 0.9240
NADPH-dependent oxidoreductase 2-alkenal reductase Q39172 AER_ARATH Arabidopsis thaliana 3 0.9213
NADPH-dependent oxidoreductase 2-alkenal reductase Q39172 AER_ARATH Arabidopsis thaliana 3 0.9213
High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A O76083 PDE9A_HUMAN Homo sapiens 3 0.9163
High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A O76083 PDE9A_HUMAN Homo sapiens 3 0.9163
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase Q8DNV6 Q8DNV6_STRR6 Streptococcus pneumoniae 3 0.9163
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase Q8DNV6 Q8DNV6_STRR6 Streptococcus pneumoniae 3 0.9163
Valacyclovir hydrolase Q86WA6 BPHL_HUMAN Homo sapiens 3 0.9154
Valacyclovir hydrolase Q86WA6 BPHL_HUMAN Homo sapiens 3 0.9154
Corticosteroid-binding globulin P08185 CBG_HUMAN Homo sapiens 3 0.9142
CmeR Q7B8P6 Q7B8P6_CAMJU Campylobacter jejuni 3 0.9142
CmeR Q7B8P6 Q7B8P6_CAMJU Campylobacter jejuni 3 0.9142
Corticosteroid-binding globulin P08185 CBG_HUMAN Homo sapiens 3 0.9142
Aldo-keto reductase family 1 member C2 P52895 AK1C2_HUMAN Homo sapiens 3 0.9137
Aldo-keto reductase family 1 member C2 P52895 AK1C2_HUMAN Homo sapiens 3 0.9137
Pantothenate synthetase P9WIL5 PANC_MYCTU Mycobacterium tuberculosis 3 0.9133
Pantothenate synthetase P9WIL5 PANC_MYCTU Mycobacterium tuberculosis 3 0.9133
Probable NDP-rhamnosyltransferase Q9ALM8 Q9ALM8_SACSN Saccharopolyspora spinosa 3 0.9132
Probable NDP-rhamnosyltransferase Q9ALM8 Q9ALM8_SACSN Saccharopolyspora spinosa 3 0.9132
HTH-type transcriptional regulator EthR P9WMC1 ETHR_MYCTU Mycobacterium tuberculosis 4 0.9122
HTH-type transcriptional regulator EthR P9WMC1 ETHR_MYCTU Mycobacterium tuberculosis 4 0.9122
Bromodomain-containing protein 2 P25440 BRD2_HUMAN Homo sapiens 3 0.9118
Bromodomain-containing protein 2 P25440 BRD2_HUMAN Homo sapiens 3 0.9118
Vitamin D(3) 25-hydroxylase C4B644 CPVDH_PSEAH Pseudonocardia autotrophica 3 0.9112
Vitamin D(3) 25-hydroxylase C4B644 CPVDH_PSEAH Pseudonocardia autotrophica 3 0.9112
Beta-lactoglobulin P02754 LACB_BOVIN Bos taurus 3 0.9063
Beta-lactoglobulin P02754 LACB_BOVIN Bos taurus 3 0.9063
Aldo-keto reductase family 1 member C2 P52895 AK1C2_HUMAN Homo sapiens 3 0.9053
Aldo-keto reductase family 1 member C2 P52895 AK1C2_HUMAN Homo sapiens 3 0.9053
Urokinase-type plasminogen activator P00749 UROK_HUMAN Homo sapiens 3 0.9033
Urokinase-type plasminogen activator P00749 UROK_HUMAN Homo sapiens 3 0.9033
Steroid Delta-isomerase P00947 SDIS_COMTE Comamonas testosteroni 3 0.9029
Steroid Delta-isomerase P00947 SDIS_COMTE Comamonas testosteroni 3 0.9029
L-lactate dehydrogenase A chain P04642 LDHA_RAT Rattus norvegicus 3 0.8965
L-lactate dehydrogenase A chain P04642 LDHA_RAT Rattus norvegicus 3 0.8965
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial Q15119 PDK2_HUMAN Homo sapiens 3 0.8958
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial Q15119 PDK2_HUMAN Homo sapiens 3 0.8958
HTH-type transcriptional repressor PurR P0ACP7 PURR_ECOLI Escherichia coli 3 0.8932
HTH-type transcriptional repressor PurR P0ACP7 PURR_ECOLI Escherichia coli 3 0.8932
Pteridine reductase O76290 O76290_TRYBB Trypanosoma brucei brucei 3 0.8920
Pteridine reductase O76290 O76290_TRYBB Trypanosoma brucei brucei 3 0.8920
Death-associated protein kinase 1 P53355 DAPK1_HUMAN Homo sapiens 4 0.8901
Death-associated protein kinase 1 P53355 DAPK1_HUMAN Homo sapiens 4 0.8901
Genome polyprotein O92972 POLG_HCVJ4 Hepatitis C virus genotype 1b 3 0.8886
Genome polyprotein O92972 POLG_HCVJ4 Hepatitis C virus genotype 1b 3 0.8886
Chitinase A Q9AMP1 Q9AMP1_VIBHA Vibrio harveyi 3 0.8859
Chitinase A Q9AMP1 Q9AMP1_VIBHA Vibrio harveyi 3 0.8859
Nicotinamide phosphoribosyltransferase P43490 NAMPT_HUMAN Homo sapiens 3 0.8821
Nicotinamide phosphoribosyltransferase P43490 NAMPT_HUMAN Homo sapiens 3 0.8821
Serine/threonine-protein kinase 10 O94804 STK10_HUMAN Homo sapiens 3 0.8816
Serine/threonine-protein kinase 10 O94804 STK10_HUMAN Homo sapiens 3 0.8816
Peroxisome proliferator-activated receptor gamma P37231 PPARG_HUMAN Homo sapiens 4 0.8806
Peroxisome proliferator-activated receptor gamma P37231 PPARG_HUMAN Homo sapiens 4 0.8806
Purine nucleoside phosphorylase DeoD-type P0ABP9 DEOD_ECO57 Escherichia coli O157:H7 3 0.8753
Purine nucleoside phosphorylase DeoD-type P0ABP9 DEOD_ECO57 Escherichia coli O157:H7 3 0.8753
Purine nucleoside phosphorylase DeoD-type Q5EEL8 DEOD_BACCE Bacillus cereus 3 0.8739
Purine nucleoside phosphorylase DeoD-type Q5EEL8 DEOD_BACCE Bacillus cereus 3 0.8739
Mycinamicin III 3''-O-methyltransferase Q49492 MYCF_MICGR Micromonospora griseorubida 2 0.8735
Mycinamicin III 3''-O-methyltransferase Q49492 MYCF_MICGR Micromonospora griseorubida 2 0.8735
Cholesterol side-chain cleavage enzyme, mitochondrial P05108 CP11A_HUMAN Homo sapiens 3 0.8718
Cholesterol side-chain cleavage enzyme, mitochondrial P05108 CP11A_HUMAN Homo sapiens 3 0.8718
Purine nucleoside phosphorylase DeoD-type Q5EEL8 DEOD_BACCE Bacillus cereus 3 0.8712
Retinol-binding protein 4 P18902 RET4_BOVIN Bos taurus 3 0.8712
Purine nucleoside phosphorylase DeoD-type Q5EEL8 DEOD_BACCE Bacillus cereus 3 0.8712
Retinol-binding protein 4 P18902 RET4_BOVIN Bos taurus 3 0.8712
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A Q9QYJ6 PDE10_RAT Rattus norvegicus 3 0.8708
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A Q9QYJ6 PDE10_RAT Rattus norvegicus 3 0.8708
Cytochrome P450 monooxygenase Q5YNS8 Q5YNS8_NOCFA Nocardia farcinica 3 0.8701
Cytochrome P450 monooxygenase Q5YNS8 Q5YNS8_NOCFA Nocardia farcinica 3 0.8701
Purine nucleoside phosphorylase DeoD-type P0ABP9 DEOD_ECO57 Escherichia coli O157:H7 3 0.8692
Purine nucleoside phosphorylase DeoD-type P0ABP9 DEOD_ECO57 Escherichia coli O157:H7 3 0.8692
Heat shock protein HSP 90-alpha P07900 HS90A_HUMAN Homo sapiens 3 0.8659
Heat shock protein HSP 90-alpha P07900 HS90A_HUMAN Homo sapiens 3 0.8659
HTH-type transcriptional repressor PurR P0ACP7 PURR_ECOLI Escherichia coli 3 0.8651
HTH-type transcriptional repressor PurR P0ACP7 PURR_ECOLI Escherichia coli 3 0.8651
Mycinamicin III 3''-O-methyltransferase Q49492 MYCF_MICGR Micromonospora griseorubida 2 0.8648
Mycinamicin III 3''-O-methyltransferase Q49492 MYCF_MICGR Micromonospora griseorubida 2 0.8648
Queuine tRNA-ribosyltransferase P28720 TGT_ZYMMO Zymomonas mobilis subsp. mobilis 3 0.8646
Queuine tRNA-ribosyltransferase P28720 TGT_ZYMMO Zymomonas mobilis subsp. mobilis 3 0.8646
Purine nucleoside phosphorylase Q8I3X4 Q8I3X4_PLAF7 Plasmodium falciparum 3 0.8637
Purine nucleoside phosphorylase Q8I3X4 Q8I3X4_PLAF7 Plasmodium falciparum 3 0.8637
HTH-type transcriptional regulator TtgR Q9AIU0 TTGR_PSEPT Pseudomonas putida 3 0.8621
HTH-type transcriptional regulator TtgR Q9AIU0 TTGR_PSEPT Pseudomonas putida 3 0.8621
Purine nucleoside phosphorylase DeoD-type P0ABP8 DEOD_ECOLI Escherichia coli 3 0.8603
Purine nucleoside phosphorylase DeoD-type P0ABP8 DEOD_ECOLI Escherichia coli 3 0.8603
Methionine aminopeptidase 2 P50579 MAP2_HUMAN Homo sapiens 3 0.8586
Methionine aminopeptidase 2 P50579 MAP2_HUMAN Homo sapiens 3 0.8586
Cytochrome P450 monooxygenase Q5YNS8 Q5YNS8_NOCFA Nocardia farcinica 3 0.8571
Cytochrome P450 monooxygenase Q5YNS8 Q5YNS8_NOCFA Nocardia farcinica 3 0.8571
Transthyretin P02767 TTHY_RAT Rattus norvegicus 3 0.8559
Cytochrome P450 monooxygenase Q5YNS8 Q5YNS8_NOCFA Nocardia farcinica 3 0.8559
Transthyretin P02767 TTHY_RAT Rattus norvegicus 3 0.8559
Cytochrome P450 monooxygenase Q5YNS8 Q5YNS8_NOCFA Nocardia farcinica 3 0.8559
Retinol dehydratase Q26490 Q26490_SPOFR Spodoptera frugiperda 3 0.8558
Retinol dehydratase Q26490 Q26490_SPOFR Spodoptera frugiperda 3 0.8558
Cytochrome P450 monooxygenase Q5YNS8 Q5YNS8_NOCFA Nocardia farcinica 3 0.8553
Cytochrome P450 monooxygenase Q5YNS8 Q5YNS8_NOCFA Nocardia farcinica 3 0.8553
High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A O76083 PDE9A_HUMAN Homo sapiens 3 0.8533
High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A O76083 PDE9A_HUMAN Homo sapiens 3 0.8533
Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase Q9TQS6 DHDH_MACFA Macaca fascicularis 3 0.8527
Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase Q9TQS6 DHDH_MACFA Macaca fascicularis 3 0.8527
Carbonic anhydrase 2 P00918 CAH2_HUMAN Homo sapiens 3 0.8525
Carbonic anhydrase 2 P00918 CAH2_HUMAN Homo sapiens 3 0.8525
Serine/threonine-protein kinase 24 Q9Y6E0 STK24_HUMAN Homo sapiens 3 0.8511
Serine/threonine-protein kinase 24 Q9Y6E0 STK24_HUMAN Homo sapiens 3 0.8511
Chitinase Q54276 Q54276_SERMA Serratia marcescens 3 0.8478
Chitinase Q54276 Q54276_SERMA Serratia marcescens 3 0.8478
17beta-hydroxysteroid dehydrogenase O93874 O93874_COCLU Cochliobolus lunatus 3 0.8475
17beta-hydroxysteroid dehydrogenase O93874 O93874_COCLU Cochliobolus lunatus 3 0.8475
Toxoflavin degrading enzyme E3SET7 E3SET7_PAEPO Paenibacillus polymyxa 3 0.8467
Toxoflavin degrading enzyme E3SET7 E3SET7_PAEPO Paenibacillus polymyxa 3 0.8467
Integrin alpha-L P20701 ITAL_HUMAN Homo sapiens 3 0.8433
Integrin alpha-L P20701 ITAL_HUMAN Homo sapiens 3 0.8433
D-aminoacyl-tRNA deacylase Q8IIS0 DTD_PLAF7 Plasmodium falciparum 3 0.8417
D-aminoacyl-tRNA deacylase Q8IIS0 DTD_PLAF7 Plasmodium falciparum 3 0.8417
Chalcone--flavanone isomerase 1 P28012 CFI1_MEDSA Medicago sativa 3 0.8413
Chalcone--flavanone isomerase 1 P28012 CFI1_MEDSA Medicago sativa 3 0.8413
Cyclic dipeptide N-prenyltransferase D1D8L6 D1D8L6_ASPFM Neosartorya fumigata 3 0.8413
Cyclic dipeptide N-prenyltransferase D1D8L6 D1D8L6_ASPFM Neosartorya fumigata 3 0.8413
Phospholipase A2, major isoenzyme P00592 PA21B_PIG Sus scrofa 3 0.8410
Phospholipase A2, major isoenzyme P00592 PA21B_PIG Sus scrofa 3 0.8410
HTH-type transcriptional repressor PurR P0ACP7 PURR_ECOLI Escherichia coli 3 0.8406
HTH-type transcriptional repressor PurR P0ACP7 PURR_ECOLI Escherichia coli 3 0.8406
ATP-dependent molecular chaperone HSP82 P02829 HSP82_YEAST Saccharomyces cerevisiae 3 0.8396
ATP-dependent molecular chaperone HSP82 P02829 HSP82_YEAST Saccharomyces cerevisiae 3 0.8396
Enoyl-[acyl-carrier-protein] reductase [NADH] P9WGR1 INHA_MYCTU Mycobacterium tuberculosis 3 0.8395
Enoyl-[acyl-carrier-protein] reductase [NADH] P9WGR1 INHA_MYCTU Mycobacterium tuberculosis 3 0.8395
Poly [ADP-ribose] polymerase tankyrase-2 Q9H2K2 TNKS2_HUMAN Homo sapiens 3 0.8384
Poly [ADP-ribose] polymerase tankyrase-2 Q9H2K2 TNKS2_HUMAN Homo sapiens 3 0.8384
Thermolysin P00800 THER_BACTH Bacillus thermoproteolyticus 3 0.8381
Thermolysin P00800 THER_BACTH Bacillus thermoproteolyticus 3 0.8381
HTH-type transcriptional repressor PurR P0ACP7 PURR_ECOLI Escherichia coli 3 0.8377
HTH-type transcriptional repressor PurR P0ACP7 PURR_ECOLI Escherichia coli 3 0.8377
Mitogen-activated protein kinase 8 P45983 MK08_HUMAN Homo sapiens 3 0.8370
Mitogen-activated protein kinase 8 P45983 MK08_HUMAN Homo sapiens 3 0.8370
Proton-gated ion channel Q7NDN8 GLIC_GLOVI Gloeobacter violaceus 3 0.8334
Proton-gated ion channel Q7NDN8 GLIC_GLOVI Gloeobacter violaceus 3 0.8334
DNA gyrase subunit A P0AES5 GYRA_SHIFL Shigella flexneri 3 0.8328
DNA gyrase subunit A P0AES5 GYRA_SHIFL Shigella flexneri 3 0.8328
Ribosomal small subunit pseudouridine synthase A P0AA43 RSUA_ECOLI Escherichia coli 3 0.8320
17-beta-hydroxysteroid dehydrogenase type 1 P14061 DHB1_HUMAN Homo sapiens 3 0.8320
Ribosomal small subunit pseudouridine synthase A P0AA43 RSUA_ECOLI Escherichia coli 3 0.8320
17-beta-hydroxysteroid dehydrogenase type 1 P14061 DHB1_HUMAN Homo sapiens 3 0.8320
Basic phospholipase A2 VRV-PL-VIIIa P59071 PA2B8_DABRR Daboia russelii 4 0.8303
Basic phospholipase A2 VRV-PL-VIIIa P59071 PA2B8_DABRR Daboia russelii 4 0.8303
Sulfotransferase 2A1 Q06520 ST2A1_HUMAN Homo sapiens 3 0.8282
Sulfotransferase 2A1 Q06520 ST2A1_HUMAN Homo sapiens 3 0.8282
Endoplasmin P41148 ENPL_CANLF Canis lupus familiaris 3 0.8266
Endoplasmin P41148 ENPL_CANLF Canis lupus familiaris 3 0.8266
Major pollen allergen Bet v 1-A P15494 BEV1A_BETPN Betula pendula 3 0.8250
Major pollen allergen Bet v 1-A P15494 BEV1A_BETPN Betula pendula 3 0.8250
3',5'-cyclic-AMP phosphodiesterase 4D Q08499 PDE4D_HUMAN Homo sapiens 4 0.8245
3',5'-cyclic-AMP phosphodiesterase 4D Q08499 PDE4D_HUMAN Homo sapiens 4 0.8245
High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A O76083 PDE9A_HUMAN Homo sapiens 3 0.8243
High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A O76083 PDE9A_HUMAN Homo sapiens 3 0.8243
Sulfotransferase 2A1 Q06520 ST2A1_HUMAN Homo sapiens 3 0.8240
Sulfotransferase 2A1 Q06520 ST2A1_HUMAN Homo sapiens 3 0.8240
Purine nucleoside phosphorylase DeoD-type O34925 DEOD_BACSU Bacillus subtilis 3 0.8237
Purine nucleoside phosphorylase DeoD-type O34925 DEOD_BACSU Bacillus subtilis 3 0.8237
Isoliquiritigenin 2'-O-methyltransferase P93324 CHOMT_MEDSA Medicago sativa 3 0.8233
Isoliquiritigenin 2'-O-methyltransferase P93324 CHOMT_MEDSA Medicago sativa 3 0.8233
Tetracycline repressor protein class D P0ACT4 TETR4_ECOLX Escherichia coli 3 0.8232
Tetracycline repressor protein class D P0ACT4 TETR4_ECOLX Escherichia coli 3 0.8232
Heat shock protein HSP 90-alpha P07900 HS90A_HUMAN Homo sapiens 3 0.8217
Heat shock protein HSP 90-alpha P07900 HS90A_HUMAN Homo sapiens 3 0.8217
HTH-type transcriptional regulator EthR P9WMC1 ETHR_MYCTU Mycobacterium tuberculosis 3 0.8214
HTH-type transcriptional regulator EthR P9WMC1 ETHR_MYCTU Mycobacterium tuberculosis 3 0.8214
Sulfotransferase 2B1 O00204 ST2B1_HUMAN Homo sapiens 2 0.8199
Sulfotransferase 2B1 O00204 ST2B1_HUMAN Homo sapiens 2 0.8199
Heat shock protein HSP 90-alpha P07900 HS90A_HUMAN Homo sapiens 3 0.8194
Heat shock protein HSP 90-alpha P07900 HS90A_HUMAN Homo sapiens 3 0.8194
Matrilysin P09237 MMP7_HUMAN Homo sapiens 3 0.8177
Matrilysin P09237 MMP7_HUMAN Homo sapiens 3 0.8177
Rhodopsin P02699 OPSD_BOVIN Bos taurus 3 0.8150
Rhodopsin P02699 OPSD_BOVIN Bos taurus 3 0.8150
Beta-secretase 1 P56817 BACE1_HUMAN Homo sapiens 3 0.8132
Beta-secretase 1 P56817 BACE1_HUMAN Homo sapiens 3 0.8132
Mitogen-activated protein kinase 14 Q16539 MK14_HUMAN Homo sapiens 3 0.8124
Mitogen-activated protein kinase 14 Q16539 MK14_HUMAN Homo sapiens 3 0.8124
Pteridine reductase 1 Q01782 PTR1_LEIMA Leishmania major 3 0.8110
Pteridine reductase 1 Q01782 PTR1_LEIMA Leishmania major 3 0.8110
Gag-Pol polyprotein P12497 POL_HV1N5 Human immunodeficiency virus type 1 group M subtype B 3 0.8109
Gag-Pol polyprotein P12497 POL_HV1N5 Human immunodeficiency virus type 1 group M subtype B 3 0.8109
Beta-elicitin cryptogein P15570 ELIB_PHYCR Phytophthora cryptogea 4 0.8093
Beta-elicitin cryptogein P15570 ELIB_PHYCR Phytophthora cryptogea 4 0.8093
Japanin M1MR49 M1MR49_RHIAP Rhipicephalus appendiculatus 4 0.8081
Japanin M1MR49 M1MR49_RHIAP Rhipicephalus appendiculatus 4 0.8081
Acetylcholinesterase P21836 ACES_MOUSE Mus musculus 2 0.8061
Acetylcholinesterase P21836 ACES_MOUSE Mus musculus 2 0.8061
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial Q15119 PDK2_HUMAN Homo sapiens 3 0.8054
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial Q15119 PDK2_HUMAN Homo sapiens 3 0.8054
Beta-secretase 1 P56817 BACE1_HUMAN Homo sapiens 2 0.8032
Beta-secretase 1 P56817 BACE1_HUMAN Homo sapiens 2 0.8032
APH(2'')-Id O68183 O68183_ENTCA Enterococcus casseliflavus 4 0.8022
APH(2'')-Id O68183 O68183_ENTCA Enterococcus casseliflavus 4 0.8022
Epidermal growth factor receptor P00533 EGFR_HUMAN Homo sapiens 3 0.8020
Epidermal growth factor receptor P00533 EGFR_HUMAN Homo sapiens 3 0.8020
Anthocyanidin 3-O-glucosyltransferase UFGT P51094 UFOG_VITVI Vitis vinifera 4 0.8019
Anthocyanidin 3-O-glucosyltransferase UFGT P51094 UFOG_VITVI Vitis vinifera 4 0.8019
Lactoylglutathione lyase Q9CPU0 LGUL_MOUSE Mus musculus 2 0.8017
Beta-lactoglobulin P02754 LACB_BOVIN Bos taurus 3 0.8017
Aldo-keto reductase family 1 member C2 P52895 AK1C2_HUMAN Homo sapiens 2 0.8017
Beta-lactoglobulin P02754 LACB_BOVIN Bos taurus 3 0.8017
Aldo-keto reductase family 1 member C2 P52895 AK1C2_HUMAN Homo sapiens 2 0.8017
Lactoylglutathione lyase Q9CPU0 LGUL_MOUSE Mus musculus 2 0.8017
Decaprenylphosphoryl-beta-D-ribose oxidase I6X8C4 I6X8C4_MYCTU Mycobacterium tuberculosis 3 0.8016
Decaprenylphosphoryl-beta-D-ribose oxidase I6X8C4 I6X8C4_MYCTU Mycobacterium tuberculosis 3 0.8016
Basic phospholipase A2 VRV-PL-VIIIa P59071 PA2B8_DABRR Daboia russelii 2 0.8005
Basic phospholipase A2 VRV-PL-VIIIa P59071 PA2B8_DABRR Daboia russelii 2 0.8005
3-alpha-hydroxysteroid dehydrogenase P23457 DIDH_RAT Rattus norvegicus 2 0.8000
3-alpha-hydroxysteroid dehydrogenase P23457 DIDH_RAT Rattus norvegicus 2 0.8000
Aldo-keto reductase family 1 member D1 P51857 AK1D1_HUMAN Homo sapiens 3 0.7992
Aldo-keto reductase family 1 member D1 P51857 AK1D1_HUMAN Homo sapiens 3 0.7992
Gag-Pol polyprotein P03367 POL_HV1BR Human immunodeficiency virus type 1 group M subtype B 5 0.7992
Gag-Pol polyprotein P03367 POL_HV1BR Human immunodeficiency virus type 1 group M subtype B 5 0.7992
3',5'-cyclic-AMP phosphodiesterase 4D Q08499 PDE4D_HUMAN Homo sapiens 3 0.7976
3',5'-cyclic-AMP phosphodiesterase 4D Q08499 PDE4D_HUMAN Homo sapiens 3 0.7976
Cytochrome P450 1A1 P04798 CP1A1_HUMAN Homo sapiens 3 0.7972
Cytochrome P450 1A1 P04798 CP1A1_HUMAN Homo sapiens 3 0.7972
cGMP-dependent 3',5'-cyclic phosphodiesterase O00408 PDE2A_HUMAN Homo sapiens 3 0.7960
Steroid C26-monooxygenase P9WPP1 CP125_MYCTU Mycobacterium tuberculosis 3 0.7960
Steroid C26-monooxygenase P9WPP1 CP125_MYCTU Mycobacterium tuberculosis 3 0.7960
cGMP-dependent 3',5'-cyclic phosphodiesterase O00408 PDE2A_HUMAN Homo sapiens 3 0.7960
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial Q15119 PDK2_HUMAN Homo sapiens 3 0.7959
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial Q15119 PDK2_HUMAN Homo sapiens 3 0.7959
Disintegrin and metalloproteinase domain-containing protein 17 P78536 ADA17_HUMAN Homo sapiens 3 0.7958
Disintegrin and metalloproteinase domain-containing protein 17 P78536 ADA17_HUMAN Homo sapiens 3 0.7958
Heat shock protein HSP 90-beta P08238 HS90B_HUMAN Homo sapiens 3 0.7951
Heat shock protein HSP 90-beta P08238 HS90B_HUMAN Homo sapiens 3 0.7951
Cytochrome P450 S6BVH1 S6BVH1_RHOER Rhodococcus erythropolis 3 0.7948
Cytochrome P450 S6BVH1 S6BVH1_RHOER Rhodococcus erythropolis 3 0.7948
Rhodopsin P02699 OPSD_BOVIN Bos taurus 3 0.7947
Rhodopsin P02699 OPSD_BOVIN Bos taurus 3 0.7947
Thymidine phosphorylase Q7CP66 TYPH_SALTY Salmonella typhimurium 3 0.7943
Thymidine phosphorylase Q7CP66 TYPH_SALTY Salmonella typhimurium 3 0.7943
CmeR Q7B8P6 Q7B8P6_CAMJU Campylobacter jejuni 2 0.7911
CmeR Q7B8P6 Q7B8P6_CAMJU Campylobacter jejuni 2 0.7911
Camphor 5-monooxygenase P00183 CPXA_PSEPU Pseudomonas putida 3 0.7910
Camphor 5-monooxygenase P00183 CPXA_PSEPU Pseudomonas putida 3 0.7910
Peroxisome proliferator-activated receptor gamma P37231 PPARG_HUMAN Homo sapiens 3 0.7882
Peroxisome proliferator-activated receptor gamma P37231 PPARG_HUMAN Homo sapiens 3 0.7882
Aldo-keto reductase family 1 member C1 Q04828 AK1C1_HUMAN Homo sapiens 2 0.7877
Aldo-keto reductase family 1 member C1 Q04828 AK1C1_HUMAN Homo sapiens 2 0.7877
Retinol-binding protein 4 P18902 RET4_BOVIN Bos taurus 4 0.7872
Retinol-binding protein 4 P18902 RET4_BOVIN Bos taurus 4 0.7872
Peptidyl-prolyl cis-trans isomerase FKBP1A P62942 FKB1A_HUMAN Homo sapiens 2 0.7868
Peptidyl-prolyl cis-trans isomerase FKBP1A P62942 FKB1A_HUMAN Homo sapiens 2 0.7868
Ferrochelatase, mitochondrial P22830 HEMH_HUMAN Homo sapiens 2 0.7867
Ferrochelatase, mitochondrial P22830 HEMH_HUMAN Homo sapiens 2 0.7867
Aldo-keto reductase family 1 member D1 P51857 AK1D1_HUMAN Homo sapiens 3 0.7856
Aldo-keto reductase family 1 member D1 P51857 AK1D1_HUMAN Homo sapiens 3 0.7856
Mitogen-activated protein kinase 14 Q16539 MK14_HUMAN Homo sapiens 3 0.7849
Mitogen-activated protein kinase 14 Q16539 MK14_HUMAN Homo sapiens 3 0.7849
Heat shock protein HSP 90-alpha P07900 HS90A_HUMAN Homo sapiens 3 0.7826
Heat shock protein HSP 90-alpha P07900 HS90A_HUMAN Homo sapiens 3 0.7826
High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A O76083 PDE9A_HUMAN Homo sapiens 3 0.7807
High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A O76083 PDE9A_HUMAN Homo sapiens 3 0.7807
17-beta-hydroxysteroid dehydrogenase type 1 P14061 DHB1_HUMAN Homo sapiens 2 0.7805
17-beta-hydroxysteroid dehydrogenase type 1 P14061 DHB1_HUMAN Homo sapiens 2 0.7805
Proto-oncogene tyrosine-protein kinase Src P00523 SRC_CHICK Gallus gallus 3 0.7791
Proto-oncogene tyrosine-protein kinase Src P00523 SRC_CHICK Gallus gallus 3 0.7791
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A Q9Y233 PDE10_HUMAN Homo sapiens 3 0.7785
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A Q9Y233 PDE10_HUMAN Homo sapiens 3 0.7785
Sulfide-quinone reductase B7JBP8 SQRD_ACIF2 Acidithiobacillus ferrooxidans) 3 0.7784
Sulfide-quinone reductase B7JBP8 SQRD_ACIF2 Acidithiobacillus ferrooxidans) 3 0.7784
Aldehyde dehydrogenase, mitochondrial P05091 ALDH2_HUMAN Homo sapiens 3 0.7773
Aldehyde dehydrogenase, mitochondrial P05091 ALDH2_HUMAN Homo sapiens 3 0.7773
Steroid Delta-isomerase P07445 SDIS_PSEPU Pseudomonas putida 2 0.7772
Steroid Delta-isomerase P07445 SDIS_PSEPU Pseudomonas putida 2 0.7772
Aldo-keto reductase family 1 member D1 P51857 AK1D1_HUMAN Homo sapiens 2 0.7771
Aldo-keto reductase family 1 member D1 P51857 AK1D1_HUMAN Homo sapiens 2 0.7771
Retinol-binding protein 4 P18902 RET4_BOVIN Bos taurus 4 0.7756
Retinol-binding protein 4 P18902 RET4_BOVIN Bos taurus 4 0.7756
Aldo-keto reductase family 1 member C2 P52895 AK1C2_HUMAN Homo sapiens 2 0.7755
Aldo-keto reductase family 1 member C2 P52895 AK1C2_HUMAN Homo sapiens 2 0.7755
Serine/threonine-protein kinase Chk1 O14757 CHK1_HUMAN Homo sapiens 3 0.7747
Serine/threonine-protein kinase Chk1 O14757 CHK1_HUMAN Homo sapiens 3 0.7747
Phosphodiesterase Q8WQX9 Q8WQX9_9TRYP Trypanosoma brucei 3 0.7739
Phosphodiesterase Q8WQX9 Q8WQX9_9TRYP Trypanosoma brucei 3 0.7739
Methionine aminopeptidase P0AE18 MAP1_ECOLI Escherichia coli 3 0.7737
Methionine aminopeptidase P0AE18 MAP1_ECOLI Escherichia coli 3 0.7737
Beta-1 adrenergic receptor P07700 ADRB1_MELGA Meleagris gallopavo 3 0.7733
Beta-1 adrenergic receptor P07700 ADRB1_MELGA Meleagris gallopavo 3 0.7733
Aldo-keto reductase family 1 member C2 P52895 AK1C2_HUMAN Homo sapiens 2 0.7719
Aldo-keto reductase family 1 member C2 P52895 AK1C2_HUMAN Homo sapiens 2 0.7719
Aurora kinase A O14965 AURKA_HUMAN Homo sapiens 3 0.7713
Aurora kinase A O14965 AURKA_HUMAN Homo sapiens 3 0.7713
Gastrotropin P51161 FABP6_HUMAN Homo sapiens 3 0.7712
Gastrotropin P51161 FABP6_HUMAN Homo sapiens 3 0.7712
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 P04191 AT2A1_RABIT Oryctolagus cuniculus 2 0.7712
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 P04191 AT2A1_RABIT Oryctolagus cuniculus 2 0.7712
Threonine--tRNA ligase P0A8M3 SYT_ECOLI Escherichia coli 3 0.7711
Threonine--tRNA ligase P0A8M3 SYT_ECOLI Escherichia coli 3 0.7711
Death-associated protein kinase 1 P53355 DAPK1_HUMAN Homo sapiens 3 0.7709
Death-associated protein kinase 1 P53355 DAPK1_HUMAN Homo sapiens 3 0.7709
Steroid Delta-isomerase P07445 SDIS_PSEPU Pseudomonas putida 2 0.7703
Steroid Delta-isomerase P07445 SDIS_PSEPU Pseudomonas putida 2 0.7703
Methylketone synthase I E0YCS2 E0YCS2_SOLHA Solanum habrochaites 2 0.7702
Methylketone synthase I E0YCS2 E0YCS2_SOLHA Solanum habrochaites 2 0.7702
Genome polyprotein P26663 POLG_HCVBK Hepatitis C virus genotype 1b 3 0.7695
Genome polyprotein P26663 POLG_HCVBK Hepatitis C virus genotype 1b 3 0.7695
NPC intracellular cholesterol transporter 1 O15118 NPC1_HUMAN Homo sapiens 4 0.7686
NPC intracellular cholesterol transporter 1 O15118 NPC1_HUMAN Homo sapiens 4 0.7686
Protein BRASSINOSTEROID INSENSITIVE 1 O22476 BRI1_ARATH Arabidopsis thaliana 3 0.7682
Protein BRASSINOSTEROID INSENSITIVE 1 O22476 BRI1_ARATH Arabidopsis thaliana 3 0.7682
Bromodomain-containing protein 2 P25440 BRD2_HUMAN Homo sapiens 3 0.7681
Bromodomain-containing protein 2 P25440 BRD2_HUMAN Homo sapiens 3 0.7681
Pentaerythritol tetranitrate reductase P71278 P71278_ENTCL Enterobacter cloacae 2 0.7674
Pentaerythritol tetranitrate reductase P71278 P71278_ENTCL Enterobacter cloacae 2 0.7674
Beta-glucuronidase P05804 BGLR_ECOLI Escherichia coli 3 0.7671
Beta-glucuronidase P05804 BGLR_ECOLI Escherichia coli 3 0.7671
Aldo-keto reductase family 1 member C3 P42330 AK1C3_HUMAN Homo sapiens 2 0.7662
Aldo-keto reductase family 1 member C3 P42330 AK1C3_HUMAN Homo sapiens 2 0.7662
Tetracycline repressor protein class H P51561 TETR8_PASMD Pasteurella multocida 2 0.7655
Tetracycline repressor protein class H P51561 TETR8_PASMD Pasteurella multocida 2 0.7655
Succinyl-CoA:acetate CoA-transferase B3EY95 SCACT_ACEAC Acetobacter aceti 3 0.7651
Succinyl-CoA:acetate CoA-transferase B3EY95 SCACT_ACEAC Acetobacter aceti 3 0.7651
Mitogen-activated protein kinase 14 Q16539 MK14_HUMAN Homo sapiens 3 0.7650
Gag-Pol polyprotein P12497 POL_HV1N5 Human immunodeficiency virus type 1 group M subtype B 3 0.7650
Gag-Pol polyprotein P12497 POL_HV1N5 Human immunodeficiency virus type 1 group M subtype B 3 0.7650
Mitogen-activated protein kinase 14 Q16539 MK14_HUMAN Homo sapiens 3 0.7650
Aldo-keto reductase family 1 member D1 P51857 AK1D1_HUMAN Homo sapiens 2 0.7648
Aldo-keto reductase family 1 member D1 P51857 AK1D1_HUMAN Homo sapiens 2 0.7648
Beta-secretase 1 P56817 BACE1_HUMAN Homo sapiens 2 0.7647
Beta-secretase 1 P56817 BACE1_HUMAN Homo sapiens 2 0.7647
Dihydrofolate reductase P00374 DYR_HUMAN Homo sapiens 3 0.7644
Dihydrofolate reductase P00374 DYR_HUMAN Homo sapiens 3 0.7644
Sulfotransferase 1A1 P50225 ST1A1_HUMAN Homo sapiens 3 0.7641
Sulfotransferase 1A1 P50225 ST1A1_HUMAN Homo sapiens 3 0.7641
Cytochrome b-c1 complex subunit 1, mitochondrial P31800 QCR1_BOVIN Bos taurus 4 0.7640
Cytochrome b-c1 complex subunit 1, mitochondrial P31800 QCR1_BOVIN Bos taurus 4 0.7640
Protein BRASSINOSTEROID INSENSITIVE 1 O22476 BRI1_ARATH Arabidopsis thaliana 3 0.7640
Protein BRASSINOSTEROID INSENSITIVE 1 O22476 BRI1_ARATH Arabidopsis thaliana 3 0.7640
Ephrin type-A receptor 2 P29317 EPHA2_HUMAN Homo sapiens 3 0.7639
Ephrin type-A receptor 2 P29317 EPHA2_HUMAN Homo sapiens 3 0.7639
HTH-type transcriptional repressor PurR P0ACP7 PURR_ECOLI Escherichia coli 3 0.7633
HTH-type transcriptional repressor PurR P0ACP7 PURR_ECOLI Escherichia coli 3 0.7633
Gag-Pol polyprotein P12497 POL_HV1N5 Human immunodeficiency virus type 1 group M subtype B 2 0.7631
Gag-Pol polyprotein P12497 POL_HV1N5 Human immunodeficiency virus type 1 group M subtype B 2 0.7631
11-beta-hydroxysteroid dehydrogenase 1 P50172 DHI1_MOUSE Mus musculus 2 0.7629
11-beta-hydroxysteroid dehydrogenase 1 P50172 DHI1_MOUSE Mus musculus 2 0.7629
NADPH dehydrogenase 1 Q02899 OYE1_SACPS Saccharomyces pastorianus 2 0.7624
NADPH dehydrogenase 1 Q02899 OYE1_SACPS Saccharomyces pastorianus 2 0.7624
Steroid Delta-isomerase P00947 SDIS_COMTE Comamonas testosteroni 2 0.7613
Steroid Delta-isomerase P00947 SDIS_COMTE Comamonas testosteroni 2 0.7613
Steroid Delta-isomerase P00947 SDIS_COMTE Comamonas testosteroni 2 0.7613
Steroid Delta-isomerase P00947 SDIS_COMTE Comamonas testosteroni 2 0.7613
Aldo-keto reductase family 1 member D1 P51857 AK1D1_HUMAN Homo sapiens 2 0.7606
Aldo-keto reductase family 1 member D1 P51857 AK1D1_HUMAN Homo sapiens 2 0.7606
4,4'-diapophytoene synthase A9JQL9 CRTM_STAAU Staphylococcus aureus 2 0.7604
4,4'-diapophytoene synthase A9JQL9 CRTM_STAAU Staphylococcus aureus 2 0.7604
Hexokinase-4 P35557 HXK4_HUMAN Homo sapiens 3 0.7602
Hexokinase-4 P35557 HXK4_HUMAN Homo sapiens 3 0.7602
Retinol-binding protein 4 P02753 RET4_HUMAN Homo sapiens 4 0.7595
Pteridine reductase O76290 O76290_TRYBB Trypanosoma brucei brucei 2 0.7595
Retinol-binding protein 4 P02753 RET4_HUMAN Homo sapiens 4 0.7595
Pteridine reductase O76290 O76290_TRYBB Trypanosoma brucei brucei 2 0.7595
Streptavidin P22629 SAV_STRAV Streptomyces avidinii 4 0.7583
Streptavidin P22629 SAV_STRAV Streptomyces avidinii 4 0.7583
Subunit alpha of sarocosine oxidase Q50LF0 Q50LF0_9CORY Corynebacterium sp. U-96 4 0.7582
Subunit alpha of sarocosine oxidase Q50LF0 Q50LF0_9CORY Corynebacterium sp. U-96 4 0.7582
Retinol-binding protein 4 P18902 RET4_BOVIN Bos taurus 4 0.7580
Retinol-binding protein 4 P18902 RET4_BOVIN Bos taurus 4 0.7580
Death-associated protein kinase 1 P53355 DAPK1_HUMAN Homo sapiens 3 0.7579
Death-associated protein kinase 1 P53355 DAPK1_HUMAN Homo sapiens 3 0.7579
Pancreatic alpha-amylase P04746 AMYP_HUMAN Homo sapiens 2 0.7571
Pancreatic alpha-amylase P04746 AMYP_HUMAN Homo sapiens 2 0.7571
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial Q15119 PDK2_HUMAN Homo sapiens 3 0.7569
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial Q15119 PDK2_HUMAN Homo sapiens 3 0.7569
Uracil phosphoribosyltransferase Q26998 UPP_TOXGO Toxoplasma gondii 3 0.7566
Uracil phosphoribosyltransferase Q26998 UPP_TOXGO Toxoplasma gondii 3 0.7566
Retinol-binding protein 4 P18902 RET4_BOVIN Bos taurus 4 0.7563
Retinol-binding protein 4 P18902 RET4_BOVIN Bos taurus 4 0.7563
Epidermal growth factor receptor P00533 EGFR_HUMAN Homo sapiens 3 0.7558
Epidermal growth factor receptor P00533 EGFR_HUMAN Homo sapiens 3 0.7558
Aldehyde dehydrogenase, mitochondrial P05091 ALDH2_HUMAN Homo sapiens 3 0.7555
Aldehyde dehydrogenase, mitochondrial P05091 ALDH2_HUMAN Homo sapiens 3 0.7555
Gag-Pol polyprotein P12497 POL_HV1N5 Human immunodeficiency virus type 1 group M subtype B 2 0.7554
Gag-Pol polyprotein P12497 POL_HV1N5 Human immunodeficiency virus type 1 group M subtype B 2 0.7554
3-ketosteroid dehydrogenase Q9RA02 Q9RA02_RHOER Rhodococcus erythropolis 2 0.7554
3-ketosteroid dehydrogenase Q9RA02 Q9RA02_RHOER Rhodococcus erythropolis 2 0.7554
Aurora kinase A O14965 AURKA_HUMAN Homo sapiens 3 0.7552
Aurora kinase A O14965 AURKA_HUMAN Homo sapiens 3 0.7552
histone deacetylase A5H660 A5H660_SCHMA Schistosoma mansoni 3 0.7546
histone deacetylase A5H660 A5H660_SCHMA Schistosoma mansoni 3 0.7546
Hypoxanthine phosphoribosyltransferase Q4DRC4 Q4DRC4_TRYCC Trypanosoma cruzi 3 0.7539
Hypoxanthine phosphoribosyltransferase Q4DRC4 Q4DRC4_TRYCC Trypanosoma cruzi 3 0.7539
Nicotinamide phosphoribosyltransferase P43490 NAMPT_HUMAN Homo sapiens 2 0.7538
Nicotinamide phosphoribosyltransferase P43490 NAMPT_HUMAN Homo sapiens 2 0.7538
Aldo-keto reductase family 1 member D1 P51857 AK1D1_HUMAN Homo sapiens 2 0.7534
RNA-dependent RNA polymerase Q6A562 Q6A562_9VIRU Thosea asigna virus 2 0.7534
Aldo-keto reductase family 1 member D1 P51857 AK1D1_HUMAN Homo sapiens 2 0.7534
RNA-dependent RNA polymerase Q6A562 Q6A562_9VIRU Thosea asigna virus 2 0.7534
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial Q15119 PDK2_HUMAN Homo sapiens 3 0.7533
ALK tyrosine kinase receptor Q9UM73 ALK_HUMAN Homo sapiens 3 0.7533
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial Q15119 PDK2_HUMAN Homo sapiens 3 0.7533
ALK tyrosine kinase receptor Q9UM73 ALK_HUMAN Homo sapiens 3 0.7533
Soluble acetylcholine receptor Q8WSF8 Q8WSF8_APLCA Aplysia californica 3 0.7529
Soluble acetylcholine receptor Q8WSF8 Q8WSF8_APLCA Aplysia californica 3 0.7529
Chalcone--flavanone isomerase 1 P28012 CFI1_MEDSA Medicago sativa 3 0.7517
Chalcone--flavanone isomerase 1 P28012 CFI1_MEDSA Medicago sativa 3 0.7517
Gag-Pol polyprotein P03367 POL_HV1BR Human immunodeficiency virus type 1 group M subtype B 3 0.7516
Gag-Pol polyprotein P03367 POL_HV1BR Human immunodeficiency virus type 1 group M subtype B 3 0.7516
Carbonic anhydrase 2 P00918 CAH2_HUMAN Homo sapiens 2 0.7513
Methylketone synthase I E0YCS2 E0YCS2_SOLHA Solanum habrochaites 2 0.7513
Methylketone synthase I E0YCS2 E0YCS2_SOLHA Solanum habrochaites 2 0.7513
Carbonic anhydrase 2 P00918 CAH2_HUMAN Homo sapiens 2 0.7513
Aldo-keto reductase family 1 member D1 P51857 AK1D1_HUMAN Homo sapiens 2 0.7496
Aldo-keto reductase family 1 member D1 P51857 AK1D1_HUMAN Homo sapiens 2 0.7496
GTPase KRas P01116 RASK_HUMAN Homo sapiens 3 0.7492
GTPase KRas P01116 RASK_HUMAN Homo sapiens 3 0.7492
Heat shock protein HSP 90-alpha P07900 HS90A_HUMAN Homo sapiens 3 0.7487
Heat shock protein HSP 90-alpha P07900 HS90A_HUMAN Homo sapiens 3 0.7487
DNA topoisomerase 1 P06612 TOP1_ECOLI Escherichia coli 3 0.7486
DNA topoisomerase 1 P06612 TOP1_ECOLI Escherichia coli 3 0.7486
Botulinum neurotoxin type B P10844 BXB_CLOBO Clostridium botulinum 3 0.7482
Botulinum neurotoxin type B P10844 BXB_CLOBO Clostridium botulinum 3 0.7482
Gag-Pol polyprotein P03367 POL_HV1BR Human immunodeficiency virus type 1 group M subtype B 3 0.7481
Gag-Pol polyprotein P03367 POL_HV1BR Human immunodeficiency virus type 1 group M subtype B 3 0.7481
Dihydrofolate reductase P0ABQ4 DYR_ECOLI Escherichia coli 4 0.7479
Dihydrofolate reductase P0ABQ4 DYR_ECOLI Escherichia coli 4 0.7479
Fatty acid-binding protein, liver P80226 FABPL_CHICK Gallus gallus 2 0.7476
Fatty acid-binding protein, liver P80226 FABPL_CHICK Gallus gallus 2 0.7476
Death-associated protein kinase 1 P53355 DAPK1_HUMAN Homo sapiens 3 0.7473
Death-associated protein kinase 1 P53355 DAPK1_HUMAN Homo sapiens 3 0.7473
Thymidylate synthase P00469 TYSY_LACCA Lacticaseibacillus casei 3 0.7472
Thymidylate synthase P00469 TYSY_LACCA Lacticaseibacillus casei 3 0.7472
Gag-Pol polyprotein P04584 POL_HV2RO Human immunodeficiency virus type 2 subtype A 3 0.7466
Gag-Pol polyprotein P04584 POL_HV2RO Human immunodeficiency virus type 2 subtype A 3 0.7466
prolyl oligopeptidase Q9X6R4 Q9X6R4_AERCA Aeromonas caviae 2 0.7465
prolyl oligopeptidase Q9X6R4 Q9X6R4_AERCA Aeromonas caviae 2 0.7465
Retinol-binding protein 2 P50120 RET2_HUMAN Homo sapiens 3 0.7461
Retinol-binding protein 2 P50120 RET2_HUMAN Homo sapiens 3 0.7461
Endothiapepsin P11838 CARP_CRYPA Cryphonectria parasitica 2 0.7458
Endothiapepsin P11838 CARP_CRYPA Cryphonectria parasitica 2 0.7458
Putative pteridine reductase 2 Q8I814 Q8I814_TRYCR Trypanosoma cruzi 4 0.7457
Putative pteridine reductase 2 Q8I814 Q8I814_TRYCR Trypanosoma cruzi 4 0.7457
Methylmalonyl-CoA decarboxylase P52045 SCPB_ECOLI Escherichia coli 3 0.7457
Methylmalonyl-CoA decarboxylase P52045 SCPB_ECOLI Escherichia coli 3 0.7457
Dipeptidyl peptidase 4 P27487 DPP4_HUMAN Homo sapiens 2 0.7455
Dipeptidyl peptidase 4 P27487 DPP4_HUMAN Homo sapiens 2 0.7455
Lethal(3)malignant brain tumor-like protein 1 Q9Y468 LMBL1_HUMAN Homo sapiens 3 0.7452
Lethal(3)malignant brain tumor-like protein 1 Q9Y468 LMBL1_HUMAN Homo sapiens 3 0.7452
Cyclin-dependent kinase 9 P50750 CDK9_HUMAN Homo sapiens 3 0.7451
Cyclin-dependent kinase 9 P50750 CDK9_HUMAN Homo sapiens 3 0.7451
Dihydrofolate reductase P22906 DYR_CANAX Candida albicans 3 0.7450
Dihydrofolate reductase P22906 DYR_CANAX Candida albicans 3 0.7450
Tetracycline repressor protein class D P0ACT4 TETR4_ECOLX Escherichia coli 3 0.7448
Tetracycline repressor protein class D P0ACT4 TETR4_ECOLX Escherichia coli 3 0.7448
3-phosphoinositide-dependent protein kinase 1 O15530 PDPK1_HUMAN Homo sapiens 3 0.7446
3-phosphoinositide-dependent protein kinase 1 O15530 PDPK1_HUMAN Homo sapiens 3 0.7446
Dihydrofolate reductase P00374 DYR_HUMAN Homo sapiens 3 0.7441
Dihydrofolate reductase P00374 DYR_HUMAN Homo sapiens 3 0.7441
Heat shock protein HSP 90-alpha P07900 HS90A_HUMAN Homo sapiens 3 0.7440
Heat shock protein HSP 90-alpha P07900 HS90A_HUMAN Homo sapiens 3 0.7440
Adenosine monophosphate-protein transferase Q8ZVF7 Q8ZVF7_PYRAE Pyrobaculum aerophilum 3 0.7439
Adenosine monophosphate-protein transferase Q8ZVF7 Q8ZVF7_PYRAE Pyrobaculum aerophilum 3 0.7439
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform P48736 PK3CG_HUMAN Homo sapiens 3 0.7422
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform P48736 PK3CG_HUMAN Homo sapiens 3 0.7422
Acetylcholinesterase P04058 ACES_TETCF Tetronarce californica 3 0.7421
Acetylcholinesterase P04058 ACES_TETCF Tetronarce californica 3 0.7421
Retinol-binding protein 4 P18902 RET4_BOVIN Bos taurus 4 0.7418
Retinol-binding protein 4 P18902 RET4_BOVIN Bos taurus 4 0.7418
Fatty acid-binding protein 10-A, liver basic Q9I8L5 FA10A_DANRE Danio rerio 2 0.7414
Fatty acid-binding protein 10-A, liver basic Q9I8L5 FA10A_DANRE Danio rerio 2 0.7414
Gag-Pol polyprotein P03367 POL_HV1BR Human immunodeficiency virus type 1 group M subtype B 4 0.7412
Gag-Pol polyprotein P03367 POL_HV1BR Human immunodeficiency virus type 1 group M subtype B 4 0.7412
2',3'-cyclic-nucleotide 3'-phosphodiesterase P16330 CN37_MOUSE Mus musculus 2 0.7407
2',3'-cyclic-nucleotide 3'-phosphodiesterase P16330 CN37_MOUSE Mus musculus 2 0.7407
Glycogen synthase kinase-3 beta P49841 GSK3B_HUMAN Homo sapiens 3 0.7401
Glycogen synthase kinase-3 beta P49841 GSK3B_HUMAN Homo sapiens 3 0.7401
Fumarate reductase subunit D P0A8Q3 FRDD_ECOLI Escherichia coli 2 0.7400
Fumarate reductase subunit D P0A8Q3 FRDD_ECOLI Escherichia coli 2 0.7400
3-hydroxyanthranilate 3,4-dioxygenase Q1LCS4 3HAO_CUPMC Cupriavidus metallidurans 2 0.7398
3-hydroxyanthranilate 3,4-dioxygenase Q1LCS4 3HAO_CUPMC Cupriavidus metallidurans 2 0.7398
3',5'-cyclic-AMP phosphodiesterase 4D Q08499 PDE4D_HUMAN Homo sapiens 2 0.7396
3',5'-cyclic-AMP phosphodiesterase 4D Q08499 PDE4D_HUMAN Homo sapiens 2 0.7396
Glycogen synthase kinase-3 beta P49841 GSK3B_HUMAN Homo sapiens 2 0.7393
Glycogen synthase kinase-3 beta P49841 GSK3B_HUMAN Homo sapiens 2 0.7393
Pheromone-binding protein ASP1 Q9U9J6 Q9U9J6_APIME Apis mellifera 2 0.7390
Pheromone-binding protein ASP1 Q9U9J6 Q9U9J6_APIME Apis mellifera 2 0.7390
CCA-adding enzyme O28126 CCA_ARCFU Archaeoglobus fulgidus 2 0.7389
CCA-adding enzyme O28126 CCA_ARCFU Archaeoglobus fulgidus 2 0.7389
Heat shock protein HSP 90-alpha P07900 HS90A_HUMAN Homo sapiens 2 0.7385
Heat shock protein HSP 90-alpha P07900 HS90A_HUMAN Homo sapiens 2 0.7385
Lactotransferrin P24627 TRFL_BOVIN Bos taurus 2 0.7383
Lactotransferrin P24627 TRFL_BOVIN Bos taurus 2 0.7383
Biotin carboxylase P24182 ACCC_ECOLI Escherichia coli 3 0.7383
Biotin carboxylase P24182 ACCC_ECOLI Escherichia coli 3 0.7383
Neocarzinostatin P0A3R9 NCZS_STRCZ Streptomyces carzinostaticus 3 0.7378
Neocarzinostatin P0A3R9 NCZS_STRCZ Streptomyces carzinostaticus 3 0.7378
Ribonuclease TTHA0252 Q5SLP1 RNSE_THET8 Thermus thermophilus 3 0.7375
Ribonuclease TTHA0252 Q5SLP1 RNSE_THET8 Thermus thermophilus 3 0.7375
Protein BRASSINOSTEROID INSENSITIVE 1 O22476 BRI1_ARATH Arabidopsis thaliana 3 0.7374
Protein BRASSINOSTEROID INSENSITIVE 1 O22476 BRI1_ARATH Arabidopsis thaliana 3 0.7374
Activin receptor type-1 Q04771 ACVR1_HUMAN Homo sapiens 2 0.7374
Activin receptor type-1 Q04771 ACVR1_HUMAN Homo sapiens 2 0.7374
Death-associated protein kinase 1 P53355 DAPK1_HUMAN Homo sapiens 3 0.7371
Death-associated protein kinase 1 P53355 DAPK1_HUMAN Homo sapiens 3 0.7371
Protease O38896 O38896_9HIV1 Human immunodeficiency virus 1 2 0.7367
Protease O38896 O38896_9HIV1 Human immunodeficiency virus 1 2 0.7367
Vitamin D3 dihydroxylase P18326 CPXE_STRGO Streptomyces griseolus 3 0.7364
Vitamin D3 dihydroxylase P18326 CPXE_STRGO Streptomyces griseolus 3 0.7364
Aldo-keto reductase family 1 member C3 P42330 AK1C3_HUMAN Homo sapiens 2 0.7362
Aldo-keto reductase family 1 member C3 P42330 AK1C3_HUMAN Homo sapiens 2 0.7362
Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial Q8N5Z0 AADAT_HUMAN Homo sapiens 2 0.7358
Prothrombin P00734 THRB_HUMAN Homo sapiens 3 0.7358
Proto-oncogene tyrosine-protein kinase receptor Ret P07949 RET_HUMAN Homo sapiens 3 0.7358
Prothrombin P00734 THRB_HUMAN Homo sapiens 3 0.7358
Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial Q8N5Z0 AADAT_HUMAN Homo sapiens 2 0.7358
Proto-oncogene tyrosine-protein kinase receptor Ret P07949 RET_HUMAN Homo sapiens 3 0.7358
Thymidylate synthase P00469 TYSY_LACCA Lacticaseibacillus casei 2 0.7357
Thymidylate synthase P00469 TYSY_LACCA Lacticaseibacillus casei 2 0.7357
Na(+):neurotransmitter symporter (Snf family) O67854 O67854_AQUAE Aquifex aeolicus 3 0.7353
Na(+):neurotransmitter symporter (Snf family) O67854 O67854_AQUAE Aquifex aeolicus 3 0.7353
Isoflavone-7-O-methyltransferase 8 O24529 7OMT8_MEDSA Medicago sativa 5 0.7353
Isoflavone-7-O-methyltransferase 8 O24529 7OMT8_MEDSA Medicago sativa 5 0.7353
Trichodiene synthase P13513 TRI5_FUSSP Fusarium sporotrichioides 2 0.7352
Trichodiene synthase P13513 TRI5_FUSSP Fusarium sporotrichioides 2 0.7352
Aldo-keto reductase family 1 member D1 P51857 AK1D1_HUMAN Homo sapiens 2 0.7349
Aldo-keto reductase family 1 member D1 P51857 AK1D1_HUMAN Homo sapiens 2 0.7349
Disintegrin and metalloproteinase domain-containing protein 17 P78536 ADA17_HUMAN Homo sapiens 4 0.7343
Disintegrin and metalloproteinase domain-containing protein 17 P78536 ADA17_HUMAN Homo sapiens 4 0.7343
Basic phospholipase A2 VRV-PL-VIIIa P59071 PA2B8_DABRR Daboia russelii 2 0.7341
Basic phospholipase A2 VRV-PL-VIIIa P59071 PA2B8_DABRR Daboia russelii 2 0.7341
Endoplasmic reticulum aminopeptidase 2 Q6P179 ERAP2_HUMAN Homo sapiens 2 0.7340
Endoplasmic reticulum aminopeptidase 2 Q6P179 ERAP2_HUMAN Homo sapiens 2 0.7340
Reaction center protein L chain P0C0Y7 RCEH_RHOSH Rhodobacter sphaeroides 3 0.7337
Reaction center protein L chain P0C0Y7 RCEH_RHOSH Rhodobacter sphaeroides 3 0.7337
Beta-1 adrenergic receptor P07700 ADRB1_MELGA Meleagris gallopavo 3 0.7336
Beta-1 adrenergic receptor P07700 ADRB1_MELGA Meleagris gallopavo 3 0.7336
Poly [ADP-ribose] polymerase tankyrase-2 Q9H2K2 TNKS2_HUMAN Homo sapiens 3 0.7334
Poly [ADP-ribose] polymerase tankyrase-2 Q9H2K2 TNKS2_HUMAN Homo sapiens 3 0.7334
2-aminohexano-6-lactam racemase Q7M181 ACLR_ACHOB Achromobacter obae 2 0.7332
2-aminohexano-6-lactam racemase Q7M181 ACLR_ACHOB Achromobacter obae 2 0.7332
IOMT 3 Q06YR3 Q06YR3_MEDTR Medicago truncatula 3 0.7330
IOMT 3 Q06YR3 Q06YR3_MEDTR Medicago truncatula 3 0.7330
Mitogen-activated protein kinase 14 Q16539 MK14_HUMAN Homo sapiens 3 0.7329
Mitogen-activated protein kinase 14 Q16539 MK14_HUMAN Homo sapiens 3 0.7329
Oxysterols receptor LXR-beta P55055 NR1H2_HUMAN Homo sapiens 3 0.7322
Oxysterols receptor LXR-beta P55055 NR1H2_HUMAN Homo sapiens 3 0.7322
Tetracycline repressor protein class D P0ACT4 TETR4_ECOLX Escherichia coli 2 0.7320
Tetracycline repressor protein class D P0ACT4 TETR4_ECOLX Escherichia coli 2 0.7320
FMN-dependent NAD(P)H:quinone oxidoreductase 1 Q9I5F3 AZOR1_PSEAE Pseudomonas aeruginosa 3 0.7314
FMN-dependent NAD(P)H:quinone oxidoreductase 1 Q9I5F3 AZOR1_PSEAE Pseudomonas aeruginosa 3 0.7314
MAP kinase-activated protein kinase 2 P49137 MAPK2_HUMAN Homo sapiens 3 0.7313
MAP kinase-activated protein kinase 2 P49137 MAPK2_HUMAN Homo sapiens 3 0.7313
Endoplasmin P41148 ENPL_CANLF Canis lupus familiaris 3 0.7313
Endoplasmin P41148 ENPL_CANLF Canis lupus familiaris 3 0.7313
Acyl-CoA:acyl-CoA alkyltransferase Q8PDX2 OLEA_XANCP Xanthomonas campestris pv. campestris 3 0.7301
Acyl-CoA:acyl-CoA alkyltransferase Q8PDX2 OLEA_XANCP Xanthomonas campestris pv. campestris 3 0.7301
Nodulin-13 P93330 NOD13_MEDTR Medicago truncatula 3 0.7300
DNA double-strand break repair protein Mre11 Q9X1X0 Q9X1X0_THEMA Thermotoga maritima MSB8 4 0.7300
Nodulin-13 P93330 NOD13_MEDTR Medicago truncatula 3 0.7300
DNA double-strand break repair protein Mre11 Q9X1X0 Q9X1X0_THEMA Thermotoga maritima MSB8 4 0.7300
17-beta-hydroxysteroid dehydrogenase type 1 P14061 DHB1_HUMAN Homo sapiens 2 0.7295
Protein LlR18A P52778 L18A_LUPLU Lupinus luteus 2 0.7295
17-beta-hydroxysteroid dehydrogenase type 1 P14061 DHB1_HUMAN Homo sapiens 2 0.7295
Protein LlR18A P52778 L18A_LUPLU Lupinus luteus 2 0.7295
Mitogen-activated protein kinase 14 Q16539 MK14_HUMAN Homo sapiens 3 0.7292
Mitogen-activated protein kinase 14 Q16539 MK14_HUMAN Homo sapiens 3 0.7292
Thymidylate synthase P00469 TYSY_LACCA Lacticaseibacillus casei 2 0.7290
Thymidylate synthase P00469 TYSY_LACCA Lacticaseibacillus casei 2 0.7290
High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A O76083 PDE9A_HUMAN Homo sapiens 3 0.7285
High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A O76083 PDE9A_HUMAN Homo sapiens 3 0.7285
Glycogen synthase kinase-3 beta P49841 GSK3B_HUMAN Homo sapiens 3 0.7280
Glycogen synthase kinase-3 beta P49841 GSK3B_HUMAN Homo sapiens 3 0.7280
Endothiapepsin P11838 CARP_CRYPA Cryphonectria parasitica 3 0.7279
Endothiapepsin P11838 CARP_CRYPA Cryphonectria parasitica 3 0.7279
Heat shock protein HSP 90-alpha P07900 HS90A_HUMAN Homo sapiens 2 0.7271
Nuclear receptor ROR-beta P45446 RORB_RAT Rattus norvegicus 2 0.7271
Nuclear receptor ROR-beta P45446 RORB_RAT Rattus norvegicus 2 0.7271
Heat shock protein HSP 90-alpha P07900 HS90A_HUMAN Homo sapiens 2 0.7271
Gag-Pol polyprotein O12158 POL_HV192 Human immunodeficiency virus type 1 group M subtype C 3 0.7263
Gag-Pol polyprotein O12158 POL_HV192 Human immunodeficiency virus type 1 group M subtype C 3 0.7263
2',3'-cyclic-nucleotide 3'-phosphodiesterase P16330 CN37_MOUSE Mus musculus 2 0.7260
2',3'-cyclic-nucleotide 3'-phosphodiesterase P16330 CN37_MOUSE Mus musculus 2 0.7260
Death-associated protein kinase 1 P53355 DAPK1_HUMAN Homo sapiens 3 0.7256
Death-associated protein kinase 1 P53355 DAPK1_HUMAN Homo sapiens 3 0.7256
Actin-related protein 3 P61157 ARP3_BOVIN Bos taurus 3 0.7255
Glutathione S-transferase F2 P46422 GSTF2_ARATH Arabidopsis thaliana 3 0.7255
Glutathione S-transferase F2 P46422 GSTF2_ARATH Arabidopsis thaliana 3 0.7255
Actin-related protein 3 P61157 ARP3_BOVIN Bos taurus 3 0.7255
ADP-ribosylation factor 1 P84080 ARF1_BOVIN Bos taurus 3 0.7251
ADP-ribosylation factor 1 P84080 ARF1_BOVIN Bos taurus 3 0.7251
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial Q15119 PDK2_HUMAN Homo sapiens 3 0.7251
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial Q15119 PDK2_HUMAN Homo sapiens 3 0.7251
Nitric oxide synthase, inducible P29477 NOS2_MOUSE Mus musculus 3 0.7248
Jasmonoyl--L-amino acid synthetase JAR1 Q9SKE2 JAR1_ARATH Arabidopsis thaliana 3 0.7248
Nitric oxide synthase, inducible P29477 NOS2_MOUSE Mus musculus 3 0.7248
Jasmonoyl--L-amino acid synthetase JAR1 Q9SKE2 JAR1_ARATH Arabidopsis thaliana 3 0.7248
High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A O76083 PDE9A_HUMAN Homo sapiens 3 0.7247
High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A O76083 PDE9A_HUMAN Homo sapiens 3 0.7247
Glucan 1,3-beta-glucosidase P29717 EXG1_CANAL Candida albicans 2 0.7246
Glucan 1,3-beta-glucosidase P29717 EXG1_CANAL Candida albicans 2 0.7246
Camphor 5-monooxygenase P00183 CPXA_PSEPU Pseudomonas putida 3 0.7246
Camphor 5-monooxygenase P00183 CPXA_PSEPU Pseudomonas putida 3 0.7246
Lanosterol 14-alpha-demethylase Q385E8 Q385E8_TRYB2 Trypanosoma brucei brucei 3 0.7245
cGMP-dependent 3',5'-cyclic phosphodiesterase O00408 PDE2A_HUMAN Homo sapiens 3 0.7245
Lanosterol 14-alpha-demethylase Q385E8 Q385E8_TRYB2 Trypanosoma brucei brucei 3 0.7245
cGMP-dependent 3',5'-cyclic phosphodiesterase O00408 PDE2A_HUMAN Homo sapiens 3 0.7245
Chalcone--flavanone isomerase 1 P28012 CFI1_MEDSA Medicago sativa 3 0.7237
Chalcone--flavanone isomerase 1 P28012 CFI1_MEDSA Medicago sativa 3 0.7237
2',3'-cyclic-nucleotide 3'-phosphodiesterase P16330 CN37_MOUSE Mus musculus 2 0.7233
2',3'-cyclic-nucleotide 3'-phosphodiesterase P16330 CN37_MOUSE Mus musculus 2 0.7233
Endothiapepsin P11838 CARP_CRYPA Cryphonectria parasitica 3 0.7229
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 P04191 AT2A1_RABIT Oryctolagus cuniculus 3 0.7229
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 P04191 AT2A1_RABIT Oryctolagus cuniculus 3 0.7229
Endothiapepsin P11838 CARP_CRYPA Cryphonectria parasitica 3 0.7229
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform O02697 PK3CG_PIG Sus scrofa 4 0.7227
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform O02697 PK3CG_PIG Sus scrofa 4 0.7227
UDP-3-O-acyl-N-acetylglucosamine deacetylase O67648 LPXC_AQUAE Aquifex aeolicus 3 0.7226
UDP-3-O-acyl-N-acetylglucosamine deacetylase O67648 LPXC_AQUAE Aquifex aeolicus 3 0.7226
Retinoic acid receptor RXR-alpha P19793 RXRA_HUMAN Homo sapiens 2 0.7225
Retinoic acid receptor RXR-alpha P19793 RXRA_HUMAN Homo sapiens 2 0.7225
Histone deacetylase 8 Q9BY41 HDAC8_HUMAN Homo sapiens 3 0.7223
Histone deacetylase 8 Q9BY41 HDAC8_HUMAN Homo sapiens 3 0.7223
Formate--tetrahydrofolate ligase Q2RM91 FTHS_MOOTA Moorella thermoacetica 2 0.7222
Formate--tetrahydrofolate ligase Q2RM91 FTHS_MOOTA Moorella thermoacetica 2 0.7222
Sulfide-quinone reductase B7JBP8 SQRD_ACIF2 Acidithiobacillus ferrooxidans) 4 0.7219
Sulfide-quinone reductase B7JBP8 SQRD_ACIF2 Acidithiobacillus ferrooxidans) 4 0.7219
D-alanyl-D-alanine carboxypeptidase P15555 DAC_STRSR Streptomyces sp 2 0.7212
D-alanyl-D-alanine carboxypeptidase P15555 DAC_STRSR Streptomyces sp 2 0.7212
Serine/threonine-protein kinase pim-1 P11309 PIM1_HUMAN Homo sapiens 3 0.7211
Serine/threonine-protein kinase pim-1 P11309 PIM1_HUMAN Homo sapiens 3 0.7211
Glycogen phosphorylase, liver form P06737 PYGL_HUMAN Homo sapiens 3 0.7208
Glycogen phosphorylase, liver form P06737 PYGL_HUMAN Homo sapiens 3 0.7208
Pyruvate:ferredoxin oxidoreductase P94692 PFOR_DESAF Desulfocurvibacter africanus 3 0.7203
Pyruvate:ferredoxin oxidoreductase P94692 PFOR_DESAF Desulfocurvibacter africanus 3 0.7203
Queuine tRNA-ribosyltransferase P28720 TGT_ZYMMO Zymomonas mobilis subsp. mobilis 2 0.7202
Queuine tRNA-ribosyltransferase P28720 TGT_ZYMMO Zymomonas mobilis subsp. mobilis 2 0.7202
Sodium-dependent dopamine transporter Q7K4Y6 DAT_DROME Drosophila melanogaster 2 0.7200
Sodium-dependent dopamine transporter Q7K4Y6 DAT_DROME Drosophila melanogaster 2 0.7200
Methionine adenosyltransferase 2 subunit beta Q9NZL9 MAT2B_HUMAN Homo sapiens 4 0.7199
Methionine adenosyltransferase 2 subunit beta Q9NZL9 MAT2B_HUMAN Homo sapiens 4 0.7199
Beta-galactoside-specific lectin 4 Q6ITZ3 ML4_VISAL Viscum album 2 0.7198
Beta-galactoside-specific lectin 4 Q6ITZ3 ML4_VISAL Viscum album 2 0.7198
Nuclear receptor subfamily 1 group I member 2 O75469 NR1I2_HUMAN Homo sapiens 3 0.7198
Nuclear receptor subfamily 1 group I member 2 O75469 NR1I2_HUMAN Homo sapiens 3 0.7198
Aldo-keto reductase family 1 member B1 P15121 ALDR_HUMAN Homo sapiens 3 0.7197
Aldo-keto reductase family 1 member B1 P15121 ALDR_HUMAN Homo sapiens 3 0.7197
Cytidine and deoxycytidylate deaminase zinc-binding region Q82Y41 Q82Y41_NITEU Nitrosomonas europaea 3 0.7196
Cytidine and deoxycytidylate deaminase zinc-binding region Q82Y41 Q82Y41_NITEU Nitrosomonas europaea 3 0.7196
2',3'-cyclic-nucleotide 3'-phosphodiesterase P16330 CN37_MOUSE Mus musculus 2 0.7194
2',3'-cyclic-nucleotide 3'-phosphodiesterase P16330 CN37_MOUSE Mus musculus 2 0.7194
Steroid 17-alpha-hydroxylase/17,20 lyase P05093 CP17A_HUMAN Homo sapiens 2 0.7188
Steroid 17-alpha-hydroxylase/17,20 lyase P05093 CP17A_HUMAN Homo sapiens 2 0.7188
Endoplasmin P41148 ENPL_CANLF Canis lupus familiaris 3 0.7185
Endoplasmin P41148 ENPL_CANLF Canis lupus familiaris 3 0.7185
Guanylate kinase P15454 KGUA_YEAST Saccharomyces cerevisiae 3 0.7182
Guanylate kinase P15454 KGUA_YEAST Saccharomyces cerevisiae 3 0.7182
LIM domain kinase 1 P53667 LIMK1_HUMAN Homo sapiens 2 0.7174
LIM domain kinase 1 P53667 LIMK1_HUMAN Homo sapiens 2 0.7174
Fibroblast growth factor receptor 1 P11362 FGFR1_HUMAN Homo sapiens 2 0.7168
Fibroblast growth factor receptor 1 P11362 FGFR1_HUMAN Homo sapiens 2 0.7168
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A Q9Y233 PDE10_HUMAN Homo sapiens 2 0.7166
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A Q9Y233 PDE10_HUMAN Homo sapiens 2 0.7166
2',3'-cyclic-nucleotide 3'-phosphodiesterase P16330 CN37_MOUSE Mus musculus 3 0.7163
2',3'-cyclic-nucleotide 3'-phosphodiesterase P16330 CN37_MOUSE Mus musculus 3 0.7163
Beta-lactoglobulin P02754 LACB_BOVIN Bos taurus 3 0.7162
Beta-lactoglobulin P02754 LACB_BOVIN Bos taurus 3 0.7162
Sulfotransferase 2A1 Q06520 ST2A1_HUMAN Homo sapiens 3 0.7161
Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase Q05603 COBT_SALTY Salmonella typhimurium 2 0.7161
Sulfotransferase 2A1 Q06520 ST2A1_HUMAN Homo sapiens 3 0.7161
Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase Q05603 COBT_SALTY Salmonella typhimurium 2 0.7161
Mitochondrial poly(A) polymerase F1NBW0 F1NBW0_CHICK Gallus gallus 2 0.7159
Prothrombin P00734 THRB_HUMAN Homo sapiens 2 0.7159
Mitochondrial poly(A) polymerase F1NBW0 F1NBW0_CHICK Gallus gallus 2 0.7159
Prothrombin P00734 THRB_HUMAN Homo sapiens 2 0.7159
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 Q9Y3Q4 HCN4_HUMAN Homo sapiens 3 0.7158
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 Q9Y3Q4 HCN4_HUMAN Homo sapiens 3 0.7158
Transcriptional activator protein LasR P25084 LASR_PSEAE Pseudomonas aeruginosa 4 0.7157
Transcriptional activator protein LasR P25084 LASR_PSEAE Pseudomonas aeruginosa 4 0.7157
Cyclin-G-associated kinase O14976 GAK_HUMAN Homo sapiens 4 0.7156
Cyclin-G-associated kinase O14976 GAK_HUMAN Homo sapiens 4 0.7156
Thymidylate synthase P00469 TYSY_LACCA Lacticaseibacillus casei 3 0.7153
Thymidylate synthase P00469 TYSY_LACCA Lacticaseibacillus casei 3 0.7153
Endothiapepsin P11838 CARP_CRYPA Cryphonectria parasitica 3 0.7152
Endothiapepsin P11838 CARP_CRYPA Cryphonectria parasitica 3 0.7152
Beta-galactoside-specific lectin 1 P81446 ML1_VISAL Viscum album 3 0.7151
Beta-galactoside-specific lectin 1 P81446 ML1_VISAL Viscum album 3 0.7151
ADP compounds hydrolase NudE P45799 NUDE_ECOLI Escherichia coli 2 0.7145
ADP compounds hydrolase NudE P45799 NUDE_ECOLI Escherichia coli 2 0.7145
17-beta-hydroxysteroid dehydrogenase type 1 P14061 DHB1_HUMAN Homo sapiens 2 0.7143
17-beta-hydroxysteroid dehydrogenase type 1 P14061 DHB1_HUMAN Homo sapiens 2 0.7143
Aminoglycoside N(3)-acetyltransferase A0A3P1UCA6 Q81P86_BACAN Bacillus anthracis 3 0.7140
Aminoglycoside N(3)-acetyltransferase A0A3P1UCA6 Q81P86_BACAN Bacillus anthracis 3 0.7140
Retinol-binding protein 1 P09455 RET1_HUMAN Homo sapiens 3 0.7139
Retinol-binding protein 1 P09455 RET1_HUMAN Homo sapiens 3 0.7139
Seminal ribonuclease P00669 RNS_BOVIN Bos taurus 3 0.7137
Seminal ribonuclease P00669 RNS_BOVIN Bos taurus 3 0.7137
Abscisic acid receptor PYL2 O80992 PYL2_ARATH Arabidopsis thaliana 2 0.7137
Abscisic acid receptor PYL2 O80992 PYL2_ARATH Arabidopsis thaliana 2 0.7137
Mitogen-activated protein kinase 14 Q16539 MK14_HUMAN Homo sapiens 4 0.7133
Mitogen-activated protein kinase 14 Q16539 MK14_HUMAN Homo sapiens 4 0.7133
Sulfotransferase 2B1 O00204 ST2B1_HUMAN Homo sapiens 2 0.7132
Sulfotransferase 2B1 O00204 ST2B1_HUMAN Homo sapiens 2 0.7132
GCN5-related N-acetyltransferase B1YEL6 B1YEL6_EXIS2 Exiguobacterium sibiricum 3 0.7128
Heat shock protein HSP 90-alpha P07900 HS90A_HUMAN Homo sapiens 2 0.7128
GCN5-related N-acetyltransferase B1YEL6 B1YEL6_EXIS2 Exiguobacterium sibiricum 3 0.7128
Heat shock protein HSP 90-alpha P07900 HS90A_HUMAN Homo sapiens 2 0.7128
Polymerase acidic protein C3W5S0 C3W5S0_I09A0 Influenza A virus 2 0.7126
Polymerase acidic protein C3W5S0 C3W5S0_I09A0 Influenza A virus 2 0.7126
Endothiapepsin P11838 CARP_CRYPA Cryphonectria parasitica 3 0.7124
Endothiapepsin P11838 CARP_CRYPA Cryphonectria parasitica 3 0.7124
Nitrogenase iron protein 1 P00459 NIFH1_AZOVI Azotobacter vinelandii 3 0.7123
Nitrogenase iron protein 1 P00459 NIFH1_AZOVI Azotobacter vinelandii 3 0.7123
Bacteriorhodopsin P02945 BACR_HALSA Halobacterium salinarum 3 0.7121
Bacteriorhodopsin P02945 BACR_HALSA Halobacterium salinarum 3 0.7121
Sex hormone-binding globulin P04278 SHBG_HUMAN Homo sapiens 3 0.7120
Sex hormone-binding globulin P04278 SHBG_HUMAN Homo sapiens 3 0.7120
Nitric oxide synthase, inducible P29477 NOS2_MOUSE Mus musculus 3 0.7119
Macrophage metalloelastase P39900 MMP12_HUMAN Homo sapiens 2 0.7119
Nitric oxide synthase, inducible P29477 NOS2_MOUSE Mus musculus 3 0.7119
Macrophage metalloelastase P39900 MMP12_HUMAN Homo sapiens 2 0.7119
Purine nucleoside phosphorylase DeoD-type O34925 DEOD_BACSU Bacillus subtilis 2 0.7116
Purine nucleoside phosphorylase DeoD-type O34925 DEOD_BACSU Bacillus subtilis 2 0.7116
Chalcone--flavanone isomerase 1 P28012 CFI1_MEDSA Medicago sativa 3 0.7112
Chalcone--flavanone isomerase 1 P28012 CFI1_MEDSA Medicago sativa 3 0.7112
Ethylene receptor 1 P49333 ETR1_ARATH Arabidopsis thaliana 3 0.7111
Ethylene receptor 1 P49333 ETR1_ARATH Arabidopsis thaliana 3 0.7111
Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) P60472 UPPS_ECOLI Escherichia coli 4 0.7110
Dihydroorotate dehydrogenase (quinone), mitochondrial Q08210 PYRD_PLAF7 Plasmodium falciparum 3 0.7110
Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) P60472 UPPS_ECOLI Escherichia coli 4 0.7110
Dihydroorotate dehydrogenase (quinone), mitochondrial Q08210 PYRD_PLAF7 Plasmodium falciparum 3 0.7110
Queuine tRNA-ribosyltransferase P28720 TGT_ZYMMO Zymomonas mobilis subsp. mobilis 2 0.7109
Queuine tRNA-ribosyltransferase P28720 TGT_ZYMMO Zymomonas mobilis subsp. mobilis 2 0.7109
Anthranilate phosphoribosyltransferase P00500 TRPD_ACIAD Acinetobacter baylyi 2 0.7108
Anthranilate phosphoribosyltransferase P00500 TRPD_ACIAD Acinetobacter baylyi 2 0.7108
Protein RecA Q59560 RECA_MYCS2 Mycolicibacterium smegmatis155) 3 0.7106
Protein RecA Q59560 RECA_MYCS2 Mycolicibacterium smegmatis155) 3 0.7106
Progesterone receptor P06401 PRGR_HUMAN Homo sapiens 3 0.7105
Progesterone receptor P06401 PRGR_HUMAN Homo sapiens 3 0.7105
Purine nucleoside phosphorylase P00491 PNPH_HUMAN Homo sapiens 3 0.7104
Purine nucleoside phosphorylase P00491 PNPH_HUMAN Homo sapiens 3 0.7104
Heat shock protein HSP 90-alpha P07900 HS90A_HUMAN Homo sapiens 3 0.7101
Heat shock protein HSP 90-alpha P07900 HS90A_HUMAN Homo sapiens 3 0.7101
Nitric oxide synthase, inducible P29477 NOS2_MOUSE Mus musculus 3 0.7101
Nitric oxide synthase, inducible P29477 NOS2_MOUSE Mus musculus 3 0.7101
Poly [ADP-ribose] polymerase tankyrase-2 Q9H2K2 TNKS2_HUMAN Homo sapiens 3 0.7095
Poly [ADP-ribose] polymerase tankyrase-2 Q9H2K2 TNKS2_HUMAN Homo sapiens 3 0.7095
Hemolymph juvenile hormone binding protein Q9U556 Q9U556_BOMMO Bombyx mori 3 0.7095
Hemolymph juvenile hormone binding protein Q9U556 Q9U556_BOMMO Bombyx mori 3 0.7095
Heat shock protein HSP 90-alpha P07900 HS90A_HUMAN Homo sapiens 3 0.7094
Serine/threonine-protein kinase SKY1 Q03656 SKY1_YEAST Saccharomyces cerevisiae 2 0.7094
Serine/threonine-protein kinase SKY1 Q03656 SKY1_YEAST Saccharomyces cerevisiae 2 0.7094
Heat shock protein HSP 90-alpha P07900 HS90A_HUMAN Homo sapiens 3 0.7094
Poly [ADP-ribose] polymerase tankyrase-2 Q9H2K2 TNKS2_HUMAN Homo sapiens 3 0.7093
S-adenosylmethionine decarboxylase proenzyme P17707 DCAM_HUMAN Homo sapiens 3 0.7093
Poly [ADP-ribose] polymerase tankyrase-2 Q9H2K2 TNKS2_HUMAN Homo sapiens 3 0.7093
S-adenosylmethionine decarboxylase proenzyme P17707 DCAM_HUMAN Homo sapiens 3 0.7093
Dihydrofolate reductase P0ABQ4 DYR_ECOLI Escherichia coli 4 0.7092
Dihydrofolate reductase P0ABQ4 DYR_ECOLI Escherichia coli 4 0.7092
Glycogen phosphorylase, liver form P06737 PYGL_HUMAN Homo sapiens 3 0.7089
Glycogen phosphorylase, liver form P06737 PYGL_HUMAN Homo sapiens 3 0.7089
Single-stranded-DNA-specific exonuclease RecJ D0EM60 D0EM60_DEIRD Deinococcus radiodurans 2 0.7089
Single-stranded-DNA-specific exonuclease RecJ D0EM60 D0EM60_DEIRD Deinococcus radiodurans 2 0.7089
Mycinamicin III 3''-O-methyltransferase Q49492 MYCF_MICGR Micromonospora griseorubida 3 0.7081
Replicase polyprotein 1ab P0C6X7 R1AB_CVHSA Human SARS coronavirus 3 0.7081
SKP1-like protein 1A Q39255 SKP1A_ARATH Arabidopsis thaliana 3 0.7081
Mycinamicin III 3''-O-methyltransferase Q49492 MYCF_MICGR Micromonospora griseorubida 3 0.7081
Replicase polyprotein 1ab P0C6X7 R1AB_CVHSA Human SARS coronavirus 3 0.7081
SKP1-like protein 1A Q39255 SKP1A_ARATH Arabidopsis thaliana 3 0.7081
Peroxisome proliferator-activated receptor gamma P37231 PPARG_HUMAN Homo sapiens 2 0.7070
Peroxisome proliferator-activated receptor gamma P37231 PPARG_HUMAN Homo sapiens 2 0.7070
Histone deacetylase-like amidohydrolase Q70I53 HDAH_ALCSD Alcaligenes sp.) 3 0.7069
Histone deacetylase-like amidohydrolase Q70I53 HDAH_ALCSD Alcaligenes sp.) 3 0.7069
Histone deacetylase 8 Q9BY41 HDAC8_HUMAN Homo sapiens 2 0.7068
Histone deacetylase 8 Q9BY41 HDAC8_HUMAN Homo sapiens 2 0.7068
DNA topoisomerase 4 subunit B H7C794 PARE_ENTFA Enterococcus faecalis 2 0.7067
DNA topoisomerase 4 subunit B H7C794 PARE_ENTFA Enterococcus faecalis 2 0.7067
L-lactate dehydrogenase A chain P13491 LDHA_RABIT Oryctolagus cuniculus 2 0.7066
L-lactate dehydrogenase A chain P13491 LDHA_RABIT Oryctolagus cuniculus 2 0.7066
Beta-lactamase Q79MP6 Q79MP6_PSEAI Pseudomonas aeruginosa 2 0.7065
Dihydropteroate synthase Q81VW8 Q81VW8_BACAN Bacillus anthracis 2 0.7065
Dihydropteroate synthase Q81VW8 Q81VW8_BACAN Bacillus anthracis 2 0.7065
Beta-lactamase Q79MP6 Q79MP6_PSEAI Pseudomonas aeruginosa 2 0.7065
Endoplasmin P41148 ENPL_CANLF Canis lupus familiaris 3 0.7064
Endoplasmin P41148 ENPL_CANLF Canis lupus familiaris 3 0.7064
3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase P19992 HSD_STREX Streptomyces exfoliatus 2 0.7063
3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase P19992 HSD_STREX Streptomyces exfoliatus 2 0.7063
ABC-type polar amino acid transport system, ATPase component Q8RCC2 Q8RCC2_CALS4 Caldanaerobacter subterraneus subsp. tengcongensis 2 0.7062
Myosin heavy chain, striated muscle P24733 MYS_ARGIR Argopecten irradians 3 0.7062
ABC-type polar amino acid transport system, ATPase component Q8RCC2 Q8RCC2_CALS4 Caldanaerobacter subterraneus subsp. tengcongensis 2 0.7062
Adenosine 5'-monophosphoramidase HINT1 P80912 HINT1_RABIT Oryctolagus cuniculus 2 0.7062
Adenosine 5'-monophosphoramidase HINT1 P80912 HINT1_RABIT Oryctolagus cuniculus 2 0.7062
Myosin heavy chain, striated muscle P24733 MYS_ARGIR Argopecten irradians 3 0.7062
Fructose-1,6-bisphosphatase 1 P09467 F16P1_HUMAN Homo sapiens 3 0.7060
Aldo-keto reductase family 1 member D1 P51857 AK1D1_HUMAN Homo sapiens 2 0.7060
Beta-secretase 1 P56817 BACE1_HUMAN Homo sapiens 2 0.7060
Fructose-1,6-bisphosphatase 1 P09467 F16P1_HUMAN Homo sapiens 3 0.7060
Aldo-keto reductase family 1 member D1 P51857 AK1D1_HUMAN Homo sapiens 2 0.7060
Beta-secretase 1 P56817 BACE1_HUMAN Homo sapiens 2 0.7060
Rhodopsin kinase GRK1 P28327 GRK1_BOVIN Bos taurus 3 0.7059
Peroxisome proliferator-activated receptor gamma P37231 PPARG_HUMAN Homo sapiens 3 0.7059
Rhodopsin kinase GRK1 P28327 GRK1_BOVIN Bos taurus 3 0.7059
Peroxisome proliferator-activated receptor gamma P37231 PPARG_HUMAN Homo sapiens 3 0.7059
Acetolactate synthase, chloroplastic P17597 ILVB_ARATH Arabidopsis thaliana 2 0.7058
Acetolactate synthase, chloroplastic P17597 ILVB_ARATH Arabidopsis thaliana 2 0.7058
Bifunctional dihydrofolate reductase-thymidylate synthase Q27793 DRTS_TRYCR Trypanosoma cruzi 3 0.7057
Bifunctional dihydrofolate reductase-thymidylate synthase Q27793 DRTS_TRYCR Trypanosoma cruzi 3 0.7057
GCN5-related N-acetyltransferase B1YEL6 B1YEL6_EXIS2 Exiguobacterium sibiricum 3 0.7054
Actin-related protein 3 P61157 ARP3_BOVIN Bos taurus 3 0.7054
GCN5-related N-acetyltransferase B1YEL6 B1YEL6_EXIS2 Exiguobacterium sibiricum 3 0.7054
Actin-related protein 3 P61157 ARP3_BOVIN Bos taurus 3 0.7054
HTH-type transcriptional regulator TtgR Q9AIU0 TTGR_PSEPT Pseudomonas putida 3 0.7053
HTH-type transcriptional regulator TtgR Q9AIU0 TTGR_PSEPT Pseudomonas putida 3 0.7053
Capsid protein Q9WBP8 Q9WBP8_9VIRU Adeno-associated virus - 1 2 0.7051
Acetolactate synthase, chloroplastic P17597 ILVB_ARATH Arabidopsis thaliana 2 0.7051
Acetolactate synthase, chloroplastic P17597 ILVB_ARATH Arabidopsis thaliana 2 0.7051
Capsid protein Q9WBP8 Q9WBP8_9VIRU Adeno-associated virus - 1 2 0.7051
Nitric oxide synthase oxygenase O34453 NOSO_BACSU Bacillus subtilis 3 0.7050
Nitric oxide synthase oxygenase O34453 NOSO_BACSU Bacillus subtilis 3 0.7050
3',5'-cyclic-AMP phosphodiesterase 4D Q08499 PDE4D_HUMAN Homo sapiens 3 0.7049
3',5'-cyclic-AMP phosphodiesterase 4D Q08499 PDE4D_HUMAN Homo sapiens 3 0.7049
Fructose-1,6-bisphosphatase 1 P09467 F16P1_HUMAN Homo sapiens 2 0.7044
Retinol dehydratase Q26490 Q26490_SPOFR Spodoptera frugiperda 3 0.7044
Fructose-1,6-bisphosphatase 1 P09467 F16P1_HUMAN Homo sapiens 2 0.7044
Retinol dehydratase Q26490 Q26490_SPOFR Spodoptera frugiperda 3 0.7044
Glycogen phosphorylase, muscle form P00489 PYGM_RABIT Oryctolagus cuniculus 3 0.7039
Glycogen phosphorylase, muscle form P00489 PYGM_RABIT Oryctolagus cuniculus 3 0.7039
Prothrombin P00734 THRB_HUMAN Homo sapiens 2 0.7037
Prothrombin P00734 THRB_HUMAN Homo sapiens 2 0.7037
Sodium/potassium-transporting ATPase subunit alpha Q4H132 Q4H132_SQUAC Squalus acanthias 3 0.7036
Sodium/potassium-transporting ATPase subunit alpha Q4H132 Q4H132_SQUAC Squalus acanthias 3 0.7036
Serine/threonine-protein kinase Chk1 O14757 CHK1_HUMAN Homo sapiens 3 0.7035
Serine/threonine-protein kinase Chk1 O14757 CHK1_HUMAN Homo sapiens 3 0.7035
Poly [ADP-ribose] polymerase tankyrase-2 Q9H2K2 TNKS2_HUMAN Homo sapiens 3 0.7035
Poly [ADP-ribose] polymerase tankyrase-2 Q9H2K2 TNKS2_HUMAN Homo sapiens 3 0.7035
Queuine tRNA-ribosyltransferase P28720 TGT_ZYMMO Zymomonas mobilis subsp. mobilis 3 0.7033
Nitric oxide synthase 3 P29474 NOS3_HUMAN Homo sapiens 3 0.7033
Queuine tRNA-ribosyltransferase P28720 TGT_ZYMMO Zymomonas mobilis subsp. mobilis 3 0.7033
Nitric oxide synthase 3 P29474 NOS3_HUMAN Homo sapiens 3 0.7033
Metallophosphoesterase A3DJ38 A3DJ38_HUNT2 Clostridium thermocellum 2 0.7032
Purine nucleoside phosphorylase DeoD-type B1JL34 DEOD_YERPY Yersinia pseudotuberculosis serotype O:3 2 0.7032
Metallophosphoesterase A3DJ38 A3DJ38_HUNT2 Clostridium thermocellum 2 0.7032
Cyclin-dependent kinase 9 P50750 CDK9_HUMAN Homo sapiens 3 0.7032
Purine nucleoside phosphorylase DeoD-type B1JL34 DEOD_YERPY Yersinia pseudotuberculosis serotype O:3 2 0.7032
Cyclin-dependent kinase 9 P50750 CDK9_HUMAN Homo sapiens 3 0.7032
Genome polyprotein P26663 POLG_HCVBK Hepatitis C virus genotype 1b 2 0.7031
Genome polyprotein P26663 POLG_HCVBK Hepatitis C virus genotype 1b 2 0.7031
N-acetylhexosamine 1-kinase E8MF12 NAHK_BIFL2 Bifidobacterium longum subsp. longum 3 0.7030
N-acetylhexosamine 1-kinase E8MF12 NAHK_BIFL2 Bifidobacterium longum subsp. longum 3 0.7030
Coagulation factor X P00742 FA10_HUMAN Homo sapiens 3 0.7026
Coagulation factor X P00742 FA10_HUMAN Homo sapiens 3 0.7026
Poly [ADP-ribose] polymerase tankyrase-2 Q9H2K2 TNKS2_HUMAN Homo sapiens 3 0.7025
Poly [ADP-ribose] polymerase tankyrase-2 Q9H2K2 TNKS2_HUMAN Homo sapiens 3 0.7025
Protocatechuate 3,4-dioxygenase beta chain P00437 PCXB_PSEPU Pseudomonas putida 2 0.7025
Protocatechuate 3,4-dioxygenase beta chain P00437 PCXB_PSEPU Pseudomonas putida 2 0.7025
Chloramphenicol 3-O phosphotransferase Q56148 CPT_STRVP Streptomyces venezuelae 2 0.7024
Chloramphenicol 3-O phosphotransferase Q56148 CPT_STRVP Streptomyces venezuelae 2 0.7024
Serine/threonine-protein kinase pim-1 P11309 PIM1_HUMAN Homo sapiens 3 0.7023
Serine/threonine-protein kinase pim-1 P11309 PIM1_HUMAN Homo sapiens 3 0.7023
2',3'-cyclic-nucleotide 3'-phosphodiesterase P16330 CN37_MOUSE Mus musculus 2 0.7021
Ephrin type-B receptor 2 P54763 EPHB2_MOUSE Mus musculus 2 0.7021
2',3'-cyclic-nucleotide 3'-phosphodiesterase P16330 CN37_MOUSE Mus musculus 2 0.7021
Ephrin type-B receptor 2 P54763 EPHB2_MOUSE Mus musculus 2 0.7021
Poly [ADP-ribose] polymerase tankyrase-2 Q9H2K2 TNKS2_HUMAN Homo sapiens 3 0.7020
Poly [ADP-ribose] polymerase tankyrase-2 Q9H2K2 TNKS2_HUMAN Homo sapiens 3 0.7020
Multidrug efflux pump subunit AcrB P31224 ACRB_ECOLI Escherichia coli 3 0.7019
Multidrug efflux pump subunit AcrB P31224 ACRB_ECOLI Escherichia coli 3 0.7019
Peptidyl-prolyl cis-trans isomerase FKBP1A P62942 FKB1A_HUMAN Homo sapiens 3 0.7017
Peptidyl-prolyl cis-trans isomerase FKBP1A P62942 FKB1A_HUMAN Homo sapiens 3 0.7017
L-lactate dehydrogenase A chain P13491 LDHA_RABIT Oryctolagus cuniculus 2 0.7013
L-lactate dehydrogenase A chain P13491 LDHA_RABIT Oryctolagus cuniculus 2 0.7013
Bifunctional dihydrofolate reductase-thymidylate synthase Q07422 DRTS_TOXGO Toxoplasma gondii 3 0.7012
Bifunctional dihydrofolate reductase-thymidylate synthase Q07422 DRTS_TOXGO Toxoplasma gondii 3 0.7012
Formate--tetrahydrofolate ligase P21164 FTHS_MOOTH Moorella thermoacetica 2 0.7011
Formate--tetrahydrofolate ligase P21164 FTHS_MOOTH Moorella thermoacetica 2 0.7011
Endothiapepsin P11838 CARP_CRYPA Cryphonectria parasitica 2 0.7009
Tetracycline repressor protein class D P0ACT4 TETR4_ECOLX Escherichia coli 3 0.7009
Endothiapepsin P11838 CARP_CRYPA Cryphonectria parasitica 2 0.7009
Tetracycline repressor protein class D P0ACT4 TETR4_ECOLX Escherichia coli 3 0.7009
Cellular retinol-binding protein type II Q8UVG6 Q8UVG6_DANRE Danio rerio 3 0.7007
Cellular retinol-binding protein type II Q8UVG6 Q8UVG6_DANRE Danio rerio 3 0.7007
S-methyl-5'-thioadenosine phosphorylase Q13126 MTAP_HUMAN Homo sapiens 3 0.7006
S-methyl-5'-thioadenosine phosphorylase Q13126 MTAP_HUMAN Homo sapiens 3 0.7006
Poly [ADP-ribose] polymerase tankyrase-2 Q9H2K2 TNKS2_HUMAN Homo sapiens 4 0.7005
Poly [ADP-ribose] polymerase tankyrase-2 Q9H2K2 TNKS2_HUMAN Homo sapiens 4 0.7005
RNA polymerase sigma factor SigA Q5SKW1 Q5SKW1_THET8 Thermus thermophilus 2 0.7004
RNA polymerase sigma factor SigA Q5SKW1 Q5SKW1_THET8 Thermus thermophilus 2 0.7004

Download SDF