Alpha,4,2'-trihydroxy-4'-O-geranyldihydrochalcone - Compound Card

Alpha,4,2'-trihydroxy-4'-O-geranyldihydrochalcone

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Alpha,4,2'-trihydroxy-4'-O-geranyldihydrochalcone

Structure
Zoomed Structure
  • Family: Leguminosae/Fabaceae
  • Kingdom: Plantae
  • Class: Chalcone
Canonical Smiles C/C(=C\COc1ccc(c(c1)O)C(=O)C(Cc1ccc(cc1)O)O)/CC=C(C)C
InChI InChI=1S/C24H28O5/c1-16(2)4-5-17(3)12-13-29-20-10-11-21(22(26)15-20)24(28)23(27)14-18-6-8-19(25)9-7-18/h4,6-12,15,23,25-27H,5,13-14H2,1-3H3/b17-12+
InChIKey VDTQLOASZLCFCY-SFQUDFHCSA-N
Formula C24H28O5
HBA 5
HBD 3
MW 396.48
Rotatable Bonds 9
TPSA 86.99
LogP 4.57
Number Rings 2
Number Aromatic Rings 2
Heavy Atom Count 29
Formal Charge 0
Fraction CSP3 0.29
Exact Mass 396.19
Number of Lipinski Rule Violations 0
# Species Family Kingdom NCBI Taxonomy ID
1 Millettia usaramensis usaramensis Leguminosae/Fabaceae Plantae 53625

Showing of synonyms

  • Yenesew A, Midiwo JO, et al. (1998). Rotenoids, isoflavones and chalcones from the stem bark of Millettia usaramensis subspecies usaramensis. Phytochemistry,1998,47(2),295-300. [View] [PubMed]
Pubchem: 42607723
Chebi: 184669
Nmrshiftdb2: 70080787

No compound-protein relationship available.

Structure

SMILES: c1ccccc1C(=O)CCc2ccccc2

Level: 1

Mol. Weight: 210.28 g/mol

Structure

SMILES: c1ccccc1

Level: 0

Mol. Weight: 78.11 g/mol

No bioactivities available.

Absorption

Caco-2 (logPapp)
-4.94
Human Oral Bioavailability 20%
Bioavailable
Human Intestinal Absorption
Absorbed
Madin-Darby Canine Kidney
-4.81
Human Oral Bioavailability 50%
Bioavailable
P-Glycoprotein Inhibitor
Inhibitor
P-Glycoprotein Substrate
Non-Substrate
Skin Permeability
-2.25

Distribution

Blood-Brain Barrier (CNS)
-
Blood-Brain Barrier
Non-Penetrable
Fraction Unbound (Human)
1.18
Plasma Protein Binding
54.43
Steady State Volume of Distribution
-

Metabolism

Breast Cancer Resistance Protein
Non-Inhibitor
CYP 1A2 Inhibitor
Inhibitor
CYP 1A2 Substrate
Non-Substrate
CYP 2C19 Inhibitor
Inhibitor
CYP 2C19 Substrate
Substrate
CYP 2C9 Inhibitor
Inhibitor
CYP 2C9 Substrate
Substrate
CYP 2D6 Inhibitor
Inhibitor
CYP 2D6 Substrate
Non-Substrate
CYP 3A4 Inhibitor
Inhibitor
CYP 3A4 Substrate
Non-Substrate
OATP1B1
Non-Inhibitor
OATP1B3
Non-Inhibitor

Excretion

Clearance
6.34
Organic Cation Transporter 2
Inhibitor
Half-Life of Drug
-

Toxicity

AMES Mutagenesis
Safe
Avian
Safe
Bee
Toxic
Bioconcentration Factor
0.15
Biodegradation
Safe
Carcinogenesis
Safe
Crustacean
Toxic
Liver Injury I (DILI)
Safe
Eye Corrosion
Safe
Eye Irritation
Safe
Maximum Tolerated Dose
0.63
Liver Injury II
Toxic
hERG Blockers
Safe
Daphnia Maga
6.37
Micronucleos
Toxic
NR-AhR
Safe
NR-AR
Safe
NR-AR-LBD
Safe
NR-Aromatase
Safe
NR-ER
Safe
NR-ER-LBD
Safe
NR-GR
Safe
NR-PPAR-gamma
Safe
NR-TR
Safe
T. Pyriformis
-6.42
Rat (Acute)
1.94
Rat (Chronic Oral)
2.82
Fathead Minnow
5.35
Respiratory Disease
Toxic
Skin Sensitisation
Safe
SR-ARE
Toxic
SR-ATAD5
Safe
SR-HSE
Safe
SR-MMP
Toxic
SR-p53
Safe

General Properties

Boiling Point
446.49
Hydration Free Energy
-7.06
Log(D) at pH=7.4
3.91
Log(P)
5.29
Log S
-6.02
Log(Vapor Pressure)
-8.29
Melting Point
124.11
pKa Acid
7.9
pKa Basic
6.11
Protein Name UniProt ID Entry Name Species #Pharmacophore Points Probability (0.7 ≤ Tversky Score ≤ 1.0)
D-aminoacyl-tRNA deacylase Q8IIS0 DTD_PLAF7 Plasmodium falciparum 3 0.9614
D-aminoacyl-tRNA deacylase Q8IIS0 DTD_PLAF7 Plasmodium falciparum 3 0.9614
Chitinase A Q9AMP1 Q9AMP1_VIBHA Vibrio harveyi 3 0.9606
Chitinase A Q9AMP1 Q9AMP1_VIBHA Vibrio harveyi 3 0.9606
Carbonic anhydrase 2 P00918 CAH2_HUMAN Homo sapiens 3 0.9564
Carbonic anhydrase 2 P00918 CAH2_HUMAN Homo sapiens 3 0.9564
Corticosteroid-binding globulin P08185 CBG_HUMAN Homo sapiens 3 0.9526
Corticosteroid-binding globulin P08185 CBG_HUMAN Homo sapiens 3 0.9526
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 P04191 AT2A1_RABIT Oryctolagus cuniculus 3 0.9485
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 P04191 AT2A1_RABIT Oryctolagus cuniculus 3 0.9485
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A Q9Y233 PDE10_HUMAN Homo sapiens 3 0.9414
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A Q9Y233 PDE10_HUMAN Homo sapiens 3 0.9414
Neocarzinostatin P0A3R9 NCZS_STRCZ Streptomyces carzinostaticus 3 0.9411
Neocarzinostatin P0A3R9 NCZS_STRCZ Streptomyces carzinostaticus 3 0.9411
Histone deacetylase 4 P56524 HDAC4_HUMAN Homo sapiens 3 0.9407
Histone deacetylase 4 P56524 HDAC4_HUMAN Homo sapiens 3 0.9407
Retinoic acid receptor RXR-alpha P19793 RXRA_HUMAN Homo sapiens 3 0.9351
Retinoic acid receptor RXR-alpha P19793 RXRA_HUMAN Homo sapiens 3 0.9351
NADPH-dependent oxidoreductase 2-alkenal reductase Q39172 AER_ARATH Arabidopsis thaliana 3 0.9350
NADPH-dependent oxidoreductase 2-alkenal reductase Q39172 AER_ARATH Arabidopsis thaliana 3 0.9350
Lactotransferrin P24627 TRFL_BOVIN Bos taurus 3 0.9312
Lactotransferrin P24627 TRFL_BOVIN Bos taurus 3 0.9312
Aldo-keto reductase family 1 member C2 P52895 AK1C2_HUMAN Homo sapiens 3 0.9270
Aldo-keto reductase family 1 member C2 P52895 AK1C2_HUMAN Homo sapiens 3 0.9270
Carbonic anhydrase 2 P00918 CAH2_HUMAN Homo sapiens 3 0.9259
Carbonic anhydrase 2 P00918 CAH2_HUMAN Homo sapiens 3 0.9259
3',5'-cyclic-AMP phosphodiesterase 4D Q08499 PDE4D_HUMAN Homo sapiens 3 0.9249
3',5'-cyclic-AMP phosphodiesterase 4D Q08499 PDE4D_HUMAN Homo sapiens 3 0.9249
Norsolorinic acid synthase Q12053 AFLC_ASPPU Aspergillus parasiticus 3 0.9232
Norsolorinic acid synthase Q12053 AFLC_ASPPU Aspergillus parasiticus 3 0.9232
Chitinase Q54276 Q54276_SERMA Serratia marcescens 3 0.9219
Chitinase Q54276 Q54276_SERMA Serratia marcescens 3 0.9219
L-lactate dehydrogenase A chain P04642 LDHA_RAT Rattus norvegicus 3 0.9186
L-lactate dehydrogenase A chain P04642 LDHA_RAT Rattus norvegicus 3 0.9186
Serine/threonine-protein kinase 10 O94804 STK10_HUMAN Homo sapiens 3 0.9179
Serine/threonine-protein kinase 10 O94804 STK10_HUMAN Homo sapiens 3 0.9179
Dihydrofolate reductase P00378 DYR_CHICK Gallus gallus 3 0.9111
Dihydrofolate reductase P00378 DYR_CHICK Gallus gallus 3 0.9111
CmeR Q7B8P6 Q7B8P6_CAMJU Campylobacter jejuni 3 0.9100
CmeR Q7B8P6 Q7B8P6_CAMJU Campylobacter jejuni 3 0.9100
Thymidylate synthase P0A886 TYSY_ECO57 Escherichia coli O157:H7 3 0.9056
Thymidylate synthase P0A886 TYSY_ECO57 Escherichia coli O157:H7 3 0.9056
Phosphodiesterase Q8WQX9 Q8WQX9_9TRYP Trypanosoma brucei 4 0.9018
Phosphodiesterase Q8WQX9 Q8WQX9_9TRYP Trypanosoma brucei 4 0.9018
Stromelysin-1 P08254 MMP3_HUMAN Homo sapiens 3 0.9009
Stromelysin-1 P08254 MMP3_HUMAN Homo sapiens 3 0.9009
Endothiapepsin P11838 CARP_CRYPA Cryphonectria parasitica 3 0.9002
Endothiapepsin P11838 CARP_CRYPA Cryphonectria parasitica 3 0.9002
HTH-type transcriptional regulator TtgR Q9AIU0 TTGR_PSEPT Pseudomonas putida 3 0.8992
Carbonic anhydrase 2 P00918 CAH2_HUMAN Homo sapiens 3 0.8992
HTH-type transcriptional regulator TtgR Q9AIU0 TTGR_PSEPT Pseudomonas putida 3 0.8992
Carbonic anhydrase 2 P00918 CAH2_HUMAN Homo sapiens 3 0.8992
Cytohesin-2 Q99418 CYH2_HUMAN Homo sapiens 3 0.8944
Cytohesin-2 Q99418 CYH2_HUMAN Homo sapiens 3 0.8944
Endothiapepsin P11838 CARP_CRYPA Cryphonectria parasitica 3 0.8942
Endothiapepsin P11838 CARP_CRYPA Cryphonectria parasitica 3 0.8942
Mitogen-activated protein kinase 14 Q16539 MK14_HUMAN Homo sapiens 3 0.8922
Mitogen-activated protein kinase 14 Q16539 MK14_HUMAN Homo sapiens 3 0.8922
NAD-capped RNA hydrolase NudC P32664 NUDC_ECOLI Escherichia coli 3 0.8917
NAD-capped RNA hydrolase NudC P32664 NUDC_ECOLI Escherichia coli 3 0.8917
3',5'-cyclic-AMP phosphodiesterase 4D Q08499 PDE4D_HUMAN Homo sapiens 3 0.8915
3',5'-cyclic-AMP phosphodiesterase 4D Q08499 PDE4D_HUMAN Homo sapiens 3 0.8915
Serine/threonine-protein kinase SKY1 Q03656 SKY1_YEAST Saccharomyces cerevisiae 3 0.8905
Serine/threonine-protein kinase SKY1 Q03656 SKY1_YEAST Saccharomyces cerevisiae 3 0.8905
Heat shock protein HSP 90-alpha P07900 HS90A_HUMAN Homo sapiens 3 0.8905
Heat shock protein HSP 90-alpha P07900 HS90A_HUMAN Homo sapiens 3 0.8905
Bromodomain-containing protein 2 P25440 BRD2_HUMAN Homo sapiens 4 0.8877
Bromodomain-containing protein 2 P25440 BRD2_HUMAN Homo sapiens 4 0.8877
Probable NDP-rhamnosyltransferase Q9ALM8 Q9ALM8_SACSN Saccharopolyspora spinosa 3 0.8875
Probable NDP-rhamnosyltransferase Q9ALM8 Q9ALM8_SACSN Saccharopolyspora spinosa 3 0.8875
Proton-gated ion channel Q7NDN8 GLIC_GLOVI Gloeobacter violaceus 3 0.8874
Proton-gated ion channel Q7NDN8 GLIC_GLOVI Gloeobacter violaceus 3 0.8874
Purine nucleoside phosphorylase DeoD-type P0ABP9 DEOD_ECO57 Escherichia coli O157:H7 3 0.8871
Purine nucleoside phosphorylase DeoD-type P0ABP9 DEOD_ECO57 Escherichia coli O157:H7 3 0.8871
Purine nucleoside phosphorylase DeoD-type Q5EEL8 DEOD_BACCE Bacillus cereus 3 0.8836
Purine nucleoside phosphorylase DeoD-type Q5EEL8 DEOD_BACCE Bacillus cereus 3 0.8836
Phospholipase A2, major isoenzyme P00592 PA21B_PIG Sus scrofa 3 0.8828
Phospholipase A2, major isoenzyme P00592 PA21B_PIG Sus scrofa 3 0.8828
Thymidylate synthase P00469 TYSY_LACCA Lacticaseibacillus casei 3 0.8825
Thymidylate synthase P00469 TYSY_LACCA Lacticaseibacillus casei 3 0.8825
Purine nucleoside phosphorylase DeoD-type P0ABP9 DEOD_ECO57 Escherichia coli O157:H7 3 0.8803
Purine nucleoside phosphorylase DeoD-type P0ABP9 DEOD_ECO57 Escherichia coli O157:H7 3 0.8803
Pantothenate synthetase P9WIL5 PANC_MYCTU Mycobacterium tuberculosis 3 0.8801
Pantothenate synthetase P9WIL5 PANC_MYCTU Mycobacterium tuberculosis 3 0.8801
Purine nucleoside phosphorylase DeoD-type Q5EEL8 DEOD_BACCE Bacillus cereus 3 0.8792
Purine nucleoside phosphorylase DeoD-type Q5EEL8 DEOD_BACCE Bacillus cereus 3 0.8792
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A Q9QYJ6 PDE10_RAT Rattus norvegicus 3 0.8781
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A Q9QYJ6 PDE10_RAT Rattus norvegicus 3 0.8781
Prothrombin P00734 THRB_HUMAN Homo sapiens 3 0.8775
Prothrombin P00734 THRB_HUMAN Homo sapiens 3 0.8775
Sex hormone-binding globulin P04278 SHBG_HUMAN Homo sapiens 3 0.8772
Sex hormone-binding globulin P04278 SHBG_HUMAN Homo sapiens 3 0.8772
Aldo-keto reductase family 1 member C2 P52895 AK1C2_HUMAN Homo sapiens 3 0.8763
Aldo-keto reductase family 1 member C2 P52895 AK1C2_HUMAN Homo sapiens 3 0.8763
Integrin alpha-L P20701 ITAL_HUMAN Homo sapiens 3 0.8760
Integrin alpha-L P20701 ITAL_HUMAN Homo sapiens 3 0.8760
Na(+):neurotransmitter symporter (Snf family) O67854 O67854_AQUAE Aquifex aeolicus 3 0.8755
Na(+):neurotransmitter symporter (Snf family) O67854 O67854_AQUAE Aquifex aeolicus 3 0.8755
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A Q9Y233 PDE10_HUMAN Homo sapiens 3 0.8752
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A Q9Y233 PDE10_HUMAN Homo sapiens 3 0.8752
Tetracycline repressor protein class D P0ACT4 TETR4_ECOLX Escherichia coli 3 0.8745
Tetracycline repressor protein class D P0ACT4 TETR4_ECOLX Escherichia coli 3 0.8745
Urokinase-type plasminogen activator P00749 UROK_HUMAN Homo sapiens 3 0.8738
Urokinase-type plasminogen activator P00749 UROK_HUMAN Homo sapiens 3 0.8738
Death-associated protein kinase 1 P53355 DAPK1_HUMAN Homo sapiens 4 0.8732
Death-associated protein kinase 1 P53355 DAPK1_HUMAN Homo sapiens 4 0.8732
Mitogen-activated protein kinase 14 Q16539 MK14_HUMAN Homo sapiens 3 0.8725
Mitogen-activated protein kinase 14 Q16539 MK14_HUMAN Homo sapiens 3 0.8725
Cytohesin-2 Q99418 CYH2_HUMAN Homo sapiens 3 0.8721
Cytohesin-2 Q99418 CYH2_HUMAN Homo sapiens 3 0.8721
Purine nucleoside phosphorylase DeoD-type P0ABP8 DEOD_ECOLI Escherichia coli 3 0.8719
Purine nucleoside phosphorylase DeoD-type P0ABP8 DEOD_ECOLI Escherichia coli 3 0.8719
Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase Q9TQS6 DHDH_MACFA Macaca fascicularis 3 0.8668
Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase Q9TQS6 DHDH_MACFA Macaca fascicularis 3 0.8668
Nuclear receptor subfamily 4immunitygroup A member 1 P22736 NR4A1_HUMAN Homo sapiens 3 0.8655
Nuclear receptor subfamily 4immunitygroup A member 1 P22736 NR4A1_HUMAN Homo sapiens 3 0.8655
Mitogen-activated protein kinase 14 Q16539 MK14_HUMAN Homo sapiens 3 0.8604
Mitogen-activated protein kinase 14 Q16539 MK14_HUMAN Homo sapiens 3 0.8604
Mitogen-activated protein kinase 14 Q16539 MK14_HUMAN Homo sapiens 3 0.8589
Mitogen-activated protein kinase 14 Q16539 MK14_HUMAN Homo sapiens 3 0.8589
Lactoperoxidase P80025 PERL_BOVIN Bos taurus 3 0.8587
Lactoperoxidase P80025 PERL_BOVIN Bos taurus 3 0.8587
Mycocyclosin synthase P9WPP7 CP121_MYCTU Mycobacterium tuberculosis 3 0.8582
Mycocyclosin synthase P9WPP7 CP121_MYCTU Mycobacterium tuberculosis 3 0.8582
Steroid Delta-isomerase P00947 SDIS_COMTE Comamonas testosteroni 3 0.8536
Steroid Delta-isomerase P00947 SDIS_COMTE Comamonas testosteroni 3 0.8536
Epidermal growth factor receptor P00533 EGFR_HUMAN Homo sapiens 3 0.8534
Epidermal growth factor receptor P00533 EGFR_HUMAN Homo sapiens 3 0.8534
Bromodomain-containing protein 2 P25440 BRD2_HUMAN Homo sapiens 3 0.8528
Bromodomain-containing protein 2 P25440 BRD2_HUMAN Homo sapiens 3 0.8528
Abscisic acid receptor PYR1 O49686 PYR1_ARATH Arabidopsis thaliana 3 0.8525
Abscisic acid receptor PYR1 O49686 PYR1_ARATH Arabidopsis thaliana 3 0.8525
Chalcone--flavanone isomerase 1 P28012 CFI1_MEDSA Medicago sativa 3 0.8522
Chalcone--flavanone isomerase 1 P28012 CFI1_MEDSA Medicago sativa 3 0.8522
Prothrombin P00734 THRB_HUMAN Homo sapiens 3 0.8511
Prothrombin P00734 THRB_HUMAN Homo sapiens 3 0.8511
Abscisic acid receptor PYL2 O80992 PYL2_ARATH Arabidopsis thaliana 3 0.8491
Abscisic acid receptor PYL2 O80992 PYL2_ARATH Arabidopsis thaliana 3 0.8491
Acetolactate synthase, chloroplastic P17597 ILVB_ARATH Arabidopsis thaliana 3 0.8475
Acetolactate synthase, chloroplastic P17597 ILVB_ARATH Arabidopsis thaliana 3 0.8475
Beta-lactoglobulin P02754 LACB_BOVIN Bos taurus 3 0.8468
Beta-lactoglobulin P02754 LACB_BOVIN Bos taurus 3 0.8468
Carbonyl reductase [NADPH] 1 P16152 CBR1_HUMAN Homo sapiens 3 0.8460
Carbonyl reductase [NADPH] 1 P16152 CBR1_HUMAN Homo sapiens 3 0.8460
Basic phospholipase A2 VRV-PL-VIIIa P59071 PA2B8_DABRR Daboia russelii 3 0.8445
Basic phospholipase A2 VRV-PL-VIIIa P59071 PA2B8_DABRR Daboia russelii 3 0.8445
Purine nucleoside phosphorylase Q8I3X4 Q8I3X4_PLAF7 Plasmodium falciparum 3 0.8444
Purine nucleoside phosphorylase Q8I3X4 Q8I3X4_PLAF7 Plasmodium falciparum 3 0.8444
Cytidine and deoxycytidylate deaminase zinc-binding region Q82Y41 Q82Y41_NITEU Nitrosomonas europaea 4 0.8434
Cytidine and deoxycytidylate deaminase zinc-binding region Q82Y41 Q82Y41_NITEU Nitrosomonas europaea 4 0.8434
Pheromone-binding protein ASP1 Q9U9J6 Q9U9J6_APIME Apis mellifera 3 0.8432
Pheromone-binding protein ASP1 Q9U9J6 Q9U9J6_APIME Apis mellifera 3 0.8432
Serine/threonine-protein kinase 24 Q9Y6E0 STK24_HUMAN Homo sapiens 3 0.8427
Serine/threonine-protein kinase 24 Q9Y6E0 STK24_HUMAN Homo sapiens 3 0.8427
Mycocyclosin synthase P9WPP7 CP121_MYCTU Mycobacterium tuberculosis 3 0.8424
Mycocyclosin synthase P9WPP7 CP121_MYCTU Mycobacterium tuberculosis 3 0.8424
Rhodopsin kinase GRK1 P28327 GRK1_BOVIN Bos taurus 3 0.8416
Rhodopsin kinase GRK1 P28327 GRK1_BOVIN Bos taurus 3 0.8416
Gag-Pol polyprotein P12497 POL_HV1N5 Human immunodeficiency virus type 1 group M subtype B 3 0.8414
Gag-Pol polyprotein P12497 POL_HV1N5 Human immunodeficiency virus type 1 group M subtype B 3 0.8414
Endothiapepsin P11838 CARP_CRYPA Cryphonectria parasitica 3 0.8405
Endothiapepsin P11838 CARP_CRYPA Cryphonectria parasitica 3 0.8405
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial Q15119 PDK2_HUMAN Homo sapiens 3 0.8401
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial Q15119 PDK2_HUMAN Homo sapiens 3 0.8401
Replicase polyprotein 1ab P0C6X7 R1AB_CVHSA Human SARS coronavirus 4 0.8396
Replicase polyprotein 1ab P0C6X7 R1AB_CVHSA Human SARS coronavirus 4 0.8396
Beta-secretase 1 P56817 BACE1_HUMAN Homo sapiens 3 0.8393
Beta-secretase 1 P56817 BACE1_HUMAN Homo sapiens 3 0.8393
Basic phospholipase A2 VRV-PL-VIIIa P59071 PA2B8_DABRR Daboia russelii 3 0.8373
Basic phospholipase A2 VRV-PL-VIIIa P59071 PA2B8_DABRR Daboia russelii 3 0.8373
Cytohesin-2 Q99418 CYH2_HUMAN Homo sapiens 4 0.8370
Cytohesin-2 Q99418 CYH2_HUMAN Homo sapiens 4 0.8370
11-beta-hydroxysteroid dehydrogenase 1 P28845 DHI1_HUMAN Homo sapiens 4 0.8353
11-beta-hydroxysteroid dehydrogenase 1 P28845 DHI1_HUMAN Homo sapiens 4 0.8353
Mycocyclosin synthase P9WPP7 CP121_MYCTU Mycobacterium tuberculosis 3 0.8350
Mycocyclosin synthase P9WPP7 CP121_MYCTU Mycobacterium tuberculosis 3 0.8350
Carbonyl reductase [NADPH] 1 P16152 CBR1_HUMAN Homo sapiens 3 0.8349
Carbonyl reductase [NADPH] 1 P16152 CBR1_HUMAN Homo sapiens 3 0.8349
Heat shock protein HSP 90-alpha P07900 HS90A_HUMAN Homo sapiens 3 0.8333
Heat shock protein HSP 90-alpha P07900 HS90A_HUMAN Homo sapiens 3 0.8333
Basic phospholipase A2 VRV-PL-VIIIa P59071 PA2B8_DABRR Daboia russelii 4 0.8318
Basic phospholipase A2 VRV-PL-VIIIa P59071 PA2B8_DABRR Daboia russelii 4 0.8318
High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A O76083 PDE9A_HUMAN Homo sapiens 3 0.8306
High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A O76083 PDE9A_HUMAN Homo sapiens 3 0.8306
Heat shock protein HSP 90-alpha P07900 HS90A_HUMAN Homo sapiens 3 0.8303
Heat shock protein HSP 90-alpha P07900 HS90A_HUMAN Homo sapiens 3 0.8303
Heat shock protein HSP 90-alpha P07900 HS90A_HUMAN Homo sapiens 3 0.8299
Heat shock protein HSP 90-alpha P07900 HS90A_HUMAN Homo sapiens 3 0.8299
HTH-type transcriptional regulator EthR P9WMC1 ETHR_MYCTU Mycobacterium tuberculosis 3 0.8291
HTH-type transcriptional regulator EthR P9WMC1 ETHR_MYCTU Mycobacterium tuberculosis 3 0.8291
HTH-type transcriptional regulator EthR P9WMC1 ETHR_MYCTU Mycobacterium tuberculosis 4 0.8275
HTH-type transcriptional regulator EthR P9WMC1 ETHR_MYCTU Mycobacterium tuberculosis 4 0.8275
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial Q15119 PDK2_HUMAN Homo sapiens 3 0.8271
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial Q15119 PDK2_HUMAN Homo sapiens 3 0.8271
Acetolactate synthase, chloroplastic P17597 ILVB_ARATH Arabidopsis thaliana 3 0.8270
Acetolactate synthase, chloroplastic P17597 ILVB_ARATH Arabidopsis thaliana 3 0.8270
Purine nucleoside phosphorylase DeoD-type O34925 DEOD_BACSU Bacillus subtilis 3 0.8265
Purine nucleoside phosphorylase DeoD-type O34925 DEOD_BACSU Bacillus subtilis 3 0.8265
Prothrombin P00734 THRB_HUMAN Homo sapiens 3 0.8255
Prothrombin P00734 THRB_HUMAN Homo sapiens 3 0.8255
Cyclin-dependent kinase 2 P24941 CDK2_HUMAN Homo sapiens 3 0.8252
Cyclin-dependent kinase 2 P24941 CDK2_HUMAN Homo sapiens 3 0.8252
Cytochrome P450 monooxygenase Q5YNS8 Q5YNS8_NOCFA Nocardia farcinica 3 0.8238
Cytochrome P450 monooxygenase Q5YNS8 Q5YNS8_NOCFA Nocardia farcinica 3 0.8238
Mycinamicin III 3''-O-methyltransferase Q49492 MYCF_MICGR Micromonospora griseorubida 2 0.8215
Mycinamicin III 3''-O-methyltransferase Q49492 MYCF_MICGR Micromonospora griseorubida 2 0.8215
Transthyretin P02767 TTHY_RAT Rattus norvegicus 3 0.8213
Transthyretin P02767 TTHY_RAT Rattus norvegicus 3 0.8213
Aldo-keto reductase family 1 member C2 P52895 AK1C2_HUMAN Homo sapiens 3 0.8199
Aldo-keto reductase family 1 member C2 P52895 AK1C2_HUMAN Homo sapiens 3 0.8199
Retinol dehydratase Q26490 Q26490_SPOFR Spodoptera frugiperda 3 0.8192
Retinol dehydratase Q26490 Q26490_SPOFR Spodoptera frugiperda 3 0.8192
Beta-lactoglobulin P02754 LACB_BOVIN Bos taurus 3 0.8181
Beta-lactoglobulin P02754 LACB_BOVIN Bos taurus 3 0.8181
Prothrombin P00734 THRB_HUMAN Homo sapiens 3 0.8179
Prothrombin P00734 THRB_HUMAN Homo sapiens 3 0.8179
Cytochrome b6 P83791 CYB6_MASLA Mastigocladus laminosus 3 0.8174
Cytochrome b6 P83791 CYB6_MASLA Mastigocladus laminosus 3 0.8174
Protein S100-A13 Q99584 S10AD_HUMAN Homo sapiens 3 0.8169
Protein S100-A13 Q99584 S10AD_HUMAN Homo sapiens 3 0.8169
DNA topoisomerase 4 subunit B H7C794 PARE_ENTFA Enterococcus faecalis 3 0.8153
DNA topoisomerase 4 subunit B H7C794 PARE_ENTFA Enterococcus faecalis 3 0.8153
17-beta-hydroxysteroid dehydrogenase type 1 P14061 DHB1_HUMAN Homo sapiens 3 0.8148
17-beta-hydroxysteroid dehydrogenase type 1 P14061 DHB1_HUMAN Homo sapiens 3 0.8148
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial Q15119 PDK2_HUMAN Homo sapiens 3 0.8145
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial Q15119 PDK2_HUMAN Homo sapiens 3 0.8145
Mitogen-activated protein kinase 14 Q16539 MK14_HUMAN Homo sapiens 3 0.8140
Mitogen-activated protein kinase 14 Q16539 MK14_HUMAN Homo sapiens 3 0.8140
ATP-dependent molecular chaperone HSP82 P02829 HSP82_YEAST Saccharomyces cerevisiae 3 0.8128
ATP-dependent molecular chaperone HSP82 P02829 HSP82_YEAST Saccharomyces cerevisiae 3 0.8128
Fibroblast growth factor receptor 1 P11362 FGFR1_HUMAN Homo sapiens 3 0.8127
Fibroblast growth factor receptor 1 P11362 FGFR1_HUMAN Homo sapiens 3 0.8127
Abscisic acid receptor PYL1 Q8VZS8 PYL1_ARATH Arabidopsis thaliana 3 0.8126
Abscisic acid receptor PYL1 Q8VZS8 PYL1_ARATH Arabidopsis thaliana 3 0.8126
Matrilysin P09237 MMP7_HUMAN Homo sapiens 3 0.8122
Matrilysin P09237 MMP7_HUMAN Homo sapiens 3 0.8122
Cytidine and deoxycytidylate deaminase zinc-binding region Q82Y41 Q82Y41_NITEU Nitrosomonas europaea 3 0.8117
Cytidine and deoxycytidylate deaminase zinc-binding region Q82Y41 Q82Y41_NITEU Nitrosomonas europaea 3 0.8117
Carbonic anhydrase 2 P00918 CAH2_HUMAN Homo sapiens 3 0.8114
Carbonic anhydrase 2 P00918 CAH2_HUMAN Homo sapiens 3 0.8114
Chalcone--flavanone isomerase 1 P28012 CFI1_MEDSA Medicago sativa 3 0.8112
Chalcone--flavanone isomerase 1 P28012 CFI1_MEDSA Medicago sativa 3 0.8112
Acetolactate synthase catalytic subunit, mitochondrial P07342 ILVB_YEAST Saccharomyces cerevisiae 3 0.8109
Acetolactate synthase catalytic subunit, mitochondrial P07342 ILVB_YEAST Saccharomyces cerevisiae 3 0.8109
Beta-secretase 1 P56817 BACE1_HUMAN Homo sapiens 3 0.8107
Beta-secretase 1 P56817 BACE1_HUMAN Homo sapiens 3 0.8107
Lethal factor P15917 LEF_BACAN Bacillus anthracis 3 0.8090
Lethal factor P15917 LEF_BACAN Bacillus anthracis 3 0.8090
Prothrombin P00734 THRB_HUMAN Homo sapiens 3 0.8086
Prothrombin P00734 THRB_HUMAN Homo sapiens 3 0.8086
Carbonic anhydrase 2 P00918 CAH2_HUMAN Homo sapiens 3 0.8073
Carbonic anhydrase 2 P00918 CAH2_HUMAN Homo sapiens 3 0.8073
Prothrombin P00734 THRB_HUMAN Homo sapiens 3 0.8070
Beta-galactoside alpha-2,6-sialyltransferase 1 P15907 SIAT1_HUMAN Homo sapiens 4 0.8070
Prothrombin P00734 THRB_HUMAN Homo sapiens 3 0.8070
Beta-galactoside alpha-2,6-sialyltransferase 1 P15907 SIAT1_HUMAN Homo sapiens 4 0.8070
Glutamate receptor 2 P19491 GRIA2_RAT Rattus norvegicus 3 0.8068
Glutamate receptor 2 P19491 GRIA2_RAT Rattus norvegicus 3 0.8068
Pteridine reductase O76290 O76290_TRYBB Trypanosoma brucei brucei 3 0.8064
Pteridine reductase O76290 O76290_TRYBB Trypanosoma brucei brucei 3 0.8064
Aldo-keto reductase family 1 member B1 P15121 ALDR_HUMAN Homo sapiens 3 0.8056
Aldo-keto reductase family 1 member B1 P15121 ALDR_HUMAN Homo sapiens 3 0.8056
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A Q9Y233 PDE10_HUMAN Homo sapiens 3 0.8055
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A Q9Y233 PDE10_HUMAN Homo sapiens 3 0.8055
Aldo-keto reductase family 1 member D1 P51857 AK1D1_HUMAN Homo sapiens 3 0.8045
Aldo-keto reductase family 1 member D1 P51857 AK1D1_HUMAN Homo sapiens 3 0.8045
FMN-dependent NAD(P)H:quinone oxidoreductase 1 Q9I5F3 AZOR1_PSEAE Pseudomonas aeruginosa 4 0.8034
FMN-dependent NAD(P)H:quinone oxidoreductase 1 Q9I5F3 AZOR1_PSEAE Pseudomonas aeruginosa 4 0.8034
Epidermal growth factor receptor P00533 EGFR_HUMAN Homo sapiens 3 0.8029
Epidermal growth factor receptor P00533 EGFR_HUMAN Homo sapiens 3 0.8029
5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase P0AF12 MTNN_ECOLI Escherichia coli 3 0.8017
5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase P0AF12 MTNN_ECOLI Escherichia coli 3 0.8017
Lactoperoxidase P80025 PERL_BOVIN Bos taurus 3 0.8004
Lactoperoxidase P80025 PERL_BOVIN Bos taurus 3 0.8004
Nicotinamide phosphoribosyltransferase P43490 NAMPT_HUMAN Homo sapiens 3 0.8003
Nicotinamide phosphoribosyltransferase P43490 NAMPT_HUMAN Homo sapiens 3 0.8003
Cytochrome P450 monooxygenase Q5YNS8 Q5YNS8_NOCFA Nocardia farcinica 3 0.7985
Cytochrome P450 monooxygenase Q5YNS8 Q5YNS8_NOCFA Nocardia farcinica 3 0.7985
Phytohormone-binding protein CSBP A0A1S3THR8 PHBP_VIGRR Vigna radiata var. radiata 3 0.7979
Phytohormone-binding protein CSBP A0A1S3THR8 PHBP_VIGRR Vigna radiata var. radiata 3 0.7979
High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A O76083 PDE9A_HUMAN Homo sapiens 3 0.7972
High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A O76083 PDE9A_HUMAN Homo sapiens 3 0.7972
Chalcone--flavanone isomerase 1 P28012 CFI1_MEDSA Medicago sativa 4 0.7960
Chalcone--flavanone isomerase 1 P28012 CFI1_MEDSA Medicago sativa 4 0.7960
Sulfotransferase 2A1 Q06520 ST2A1_HUMAN Homo sapiens 3 0.7955
Sulfotransferase 2A1 Q06520 ST2A1_HUMAN Homo sapiens 3 0.7955
Cyclin-dependent kinase 2 P24941 CDK2_HUMAN Homo sapiens 4 0.7913
Cyclin-dependent kinase 2 P24941 CDK2_HUMAN Homo sapiens 4 0.7913
Cyclin-dependent kinase 2 P24941 CDK2_HUMAN Homo sapiens 3 0.7909
Cyclin-dependent kinase 2 P24941 CDK2_HUMAN Homo sapiens 3 0.7909
3',5'-cyclic-AMP phosphodiesterase 4D Q08499 PDE4D_HUMAN Homo sapiens 3 0.7902
3',5'-cyclic-AMP phosphodiesterase 4D Q08499 PDE4D_HUMAN Homo sapiens 3 0.7902
Neocarzinostatin P0A3R9 NCZS_STRCZ Streptomyces carzinostaticus 3 0.7898
Neocarzinostatin P0A3R9 NCZS_STRCZ Streptomyces carzinostaticus 3 0.7898
3',5'-cyclic-AMP phosphodiesterase 4D Q08499 PDE4D_HUMAN Homo sapiens 3 0.7892
3',5'-cyclic-AMP phosphodiesterase 4D Q08499 PDE4D_HUMAN Homo sapiens 3 0.7892
Japanin M1MR49 M1MR49_RHIAP Rhipicephalus appendiculatus 4 0.7857
Japanin M1MR49 M1MR49_RHIAP Rhipicephalus appendiculatus 4 0.7857
Progesterone receptor P06401 PRGR_HUMAN Homo sapiens 3 0.7855
Progesterone receptor P06401 PRGR_HUMAN Homo sapiens 3 0.7855
Mitogen-activated protein kinase 8 P45983 MK08_HUMAN Homo sapiens 3 0.7854
Mitogen-activated protein kinase 8 P45983 MK08_HUMAN Homo sapiens 3 0.7854
Isoliquiritigenin 2'-O-methyltransferase P93324 CHOMT_MEDSA Medicago sativa 3 0.7835
Isoliquiritigenin 2'-O-methyltransferase P93324 CHOMT_MEDSA Medicago sativa 3 0.7835
Lethal(3)malignant brain tumor-like protein 1 Q9Y468 LMBL1_HUMAN Homo sapiens 3 0.7829
Aldos-2-ulose dehydratase P84193 AUD_PHACH Phanerodontia chrysosporium 3 0.7829
Lethal(3)malignant brain tumor-like protein 1 Q9Y468 LMBL1_HUMAN Homo sapiens 3 0.7829
Aldos-2-ulose dehydratase P84193 AUD_PHACH Phanerodontia chrysosporium 3 0.7829
Gag-Pol polyprotein P03367 POL_HV1BR Human immunodeficiency virus type 1 group M subtype B 3 0.7828
Gag-Pol polyprotein P03367 POL_HV1BR Human immunodeficiency virus type 1 group M subtype B 3 0.7828
Dihydrofolate reductase type 1 from Tn4003 P13955 DYRA_STAAU Staphylococcus aureus 4 0.7827
Dihydrofolate reductase type 1 from Tn4003 P13955 DYRA_STAAU Staphylococcus aureus 4 0.7827
Rhodopsin P02699 OPSD_BOVIN Bos taurus 3 0.7820
Rhodopsin P02699 OPSD_BOVIN Bos taurus 3 0.7820
Toxoflavin degrading enzyme E3SET7 E3SET7_PAEPO Paenibacillus polymyxa 3 0.7816
Histone-lysine N-methyltransferase SETD7 Q8WTS6 SETD7_HUMAN Homo sapiens 4 0.7816
Pteridine reductase O76290 O76290_TRYBB Trypanosoma brucei brucei 3 0.7816
Toxoflavin degrading enzyme E3SET7 E3SET7_PAEPO Paenibacillus polymyxa 3 0.7816
Pteridine reductase O76290 O76290_TRYBB Trypanosoma brucei brucei 3 0.7816
Histone-lysine N-methyltransferase SETD7 Q8WTS6 SETD7_HUMAN Homo sapiens 4 0.7816
Capsid protein Q9WBP8 Q9WBP8_9VIRU Adeno-associated virus - 1 3 0.7815
Capsid protein Q9WBP8 Q9WBP8_9VIRU Adeno-associated virus - 1 3 0.7815
Flavoredoxin Q72HI0 Q72HI0_THET2 Thermus thermophilus 3 0.7808
Flavoredoxin Q72HI0 Q72HI0_THET2 Thermus thermophilus 3 0.7808
Peptidyl-prolyl cis-trans isomerase FKBP1A P62942 FKB1A_HUMAN Homo sapiens 2 0.7803
Peptidyl-prolyl cis-trans isomerase FKBP1A P62942 FKB1A_HUMAN Homo sapiens 2 0.7803
Gag-Pol polyprotein P05896 POL_SIVM1 Simian immunodeficiency virus 3 0.7789
Gag-Pol polyprotein P05896 POL_SIVM1 Simian immunodeficiency virus 3 0.7789
17-beta-hydroxysteroid dehydrogenase type 1 P14061 DHB1_HUMAN Homo sapiens 3 0.7787
17-beta-hydroxysteroid dehydrogenase type 1 P14061 DHB1_HUMAN Homo sapiens 3 0.7787
Serine/threonine-protein kinase Chk1 O14757 CHK1_HUMAN Homo sapiens 3 0.7786
Serine/threonine-protein kinase Chk1 O14757 CHK1_HUMAN Homo sapiens 3 0.7786
Subunit alpha of sarocosine oxidase Q50LF0 Q50LF0_9CORY Corynebacterium sp. U-96 4 0.7783
Subunit alpha of sarocosine oxidase Q50LF0 Q50LF0_9CORY Corynebacterium sp. U-96 4 0.7783
Mitogen-activated protein kinase 14 Q16539 MK14_HUMAN Homo sapiens 3 0.7771
Mitogen-activated protein kinase 14 Q16539 MK14_HUMAN Homo sapiens 3 0.7771
Beta-secretase 1 P56817 BACE1_HUMAN Homo sapiens 2 0.7769
Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase Q05603 COBT_SALTY Salmonella typhimurium 3 0.7769
Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase Q05603 COBT_SALTY Salmonella typhimurium 3 0.7769
Beta-secretase 1 P56817 BACE1_HUMAN Homo sapiens 2 0.7769
Prothrombin P00734 THRB_HUMAN Homo sapiens 3 0.7768
Prothrombin P00734 THRB_HUMAN Homo sapiens 3 0.7768
CmeR Q7B8P6 Q7B8P6_CAMJU Campylobacter jejuni 2 0.7763
CmeR Q7B8P6 Q7B8P6_CAMJU Campylobacter jejuni 2 0.7763
Serine/threonine-protein kinase pim-1 P11309 PIM1_HUMAN Homo sapiens 4 0.7751
Serine/threonine-protein kinase pim-1 P11309 PIM1_HUMAN Homo sapiens 4 0.7751
cGMP-dependent protein kinase, putative A5K0N4 A5K0N4_PLAVS Plasmodium vivax 4 0.7744
cGMP-dependent protein kinase, putative A5K0N4 A5K0N4_PLAVS Plasmodium vivax 4 0.7744
Aurora kinase A O14965 AURKA_HUMAN Homo sapiens 3 0.7741
Aurora kinase A O14965 AURKA_HUMAN Homo sapiens 3 0.7741
Flavin-dependent thymidylate synthase Q9WYT0 THYX_THEMA Thermotoga maritima 3 0.7730
Flavin-dependent thymidylate synthase Q9WYT0 THYX_THEMA Thermotoga maritima 3 0.7730
Secoisolariciresinol dehydrogenase Q94KL8 SILD_PODPE Podophyllum peltatum 4 0.7730
Secoisolariciresinol dehydrogenase Q94KL8 SILD_PODPE Podophyllum peltatum 4 0.7730
HTH-type transcriptional repressor PurR P0ACP7 PURR_ECOLI Escherichia coli 3 0.7722
HTH-type transcriptional repressor PurR P0ACP7 PURR_ECOLI Escherichia coli 3 0.7722
Repressor protein Q7X0D9 Q7X0D9_ACIAD Acinetobacter baylyi 3 0.7721
Repressor protein Q7X0D9 Q7X0D9_ACIAD Acinetobacter baylyi 3 0.7721
Casein kinase II subunit alpha P68400 CSK21_HUMAN Homo sapiens 3 0.7721
Casein kinase II subunit alpha P68400 CSK21_HUMAN Homo sapiens 3 0.7721
Phenolphthiocerol/phthiocerol polyketide synthase subunit C P96202 PPSC_MYCTU Mycobacterium tuberculosis 3 0.7720
Phenolphthiocerol/phthiocerol polyketide synthase subunit C P96202 PPSC_MYCTU Mycobacterium tuberculosis 3 0.7720
Proto-oncogene tyrosine-protein kinase Src P00523 SRC_CHICK Gallus gallus 3 0.7719
Proto-oncogene tyrosine-protein kinase Src P00523 SRC_CHICK Gallus gallus 3 0.7719
cGMP-dependent 3',5'-cyclic phosphodiesterase O00408 PDE2A_HUMAN Homo sapiens 3 0.7715
cGMP-dependent 3',5'-cyclic phosphodiesterase O00408 PDE2A_HUMAN Homo sapiens 3 0.7715
Progesterone receptor P06401 PRGR_HUMAN Homo sapiens 3 0.7714
Progesterone receptor P06401 PRGR_HUMAN Homo sapiens 3 0.7714
Anthocyanidin 3-O-glucosyltransferase UFGT P51094 UFOG_VITVI Vitis vinifera 5 0.7708
Anthocyanidin 3-O-glucosyltransferase UFGT P51094 UFOG_VITVI Vitis vinifera 5 0.7708
Prothrombin P00734 THRB_HUMAN Homo sapiens 3 0.7705
Prothrombin P00734 THRB_HUMAN Homo sapiens 3 0.7705
Nodulin-13 P93330 NOD13_MEDTR Medicago truncatula 3 0.7698
Nodulin-13 P93330 NOD13_MEDTR Medicago truncatula 3 0.7698
Aldehyde dehydrogenase, mitochondrial P05091 ALDH2_HUMAN Homo sapiens 4 0.7693
Aldehyde dehydrogenase, mitochondrial P05091 ALDH2_HUMAN Homo sapiens 4 0.7693
S-adenosylmethionine decarboxylase proenzyme P17707 DCAM_HUMAN Homo sapiens 3 0.7691
S-adenosylmethionine decarboxylase proenzyme P17707 DCAM_HUMAN Homo sapiens 3 0.7691
Beta-glucuronidase P05804 BGLR_ECOLI Escherichia coli 3 0.7686
Beta-glucuronidase P05804 BGLR_ECOLI Escherichia coli 3 0.7686
Gag-Pol polyprotein P04584 POL_HV2RO Human immunodeficiency virus type 2 subtype A 3 0.7685
Gag-Pol polyprotein P04584 POL_HV2RO Human immunodeficiency virus type 2 subtype A 3 0.7685
Cyclic dipeptide N-prenyltransferase D1D8L6 D1D8L6_ASPFM Neosartorya fumigata 3 0.7684
Cyclic dipeptide N-prenyltransferase D1D8L6 D1D8L6_ASPFM Neosartorya fumigata 3 0.7684
Seed lectin subunit I P05045 LEC1_VIGUC Vigna unguiculata subsp. cylindrica 3 0.7679
Seed lectin subunit I P05045 LEC1_VIGUC Vigna unguiculata subsp. cylindrica 3 0.7679
Cholesterol side-chain cleavage enzyme, mitochondrial P05108 CP11A_HUMAN Homo sapiens 3 0.7673
Cholesterol side-chain cleavage enzyme, mitochondrial P05108 CP11A_HUMAN Homo sapiens 3 0.7673
Aminoglycoside 3'-phosphotransferase AphA1-IAB B0VD92 B0VD92_ACIBY Acinetobacter baumannii 3 0.7670
Aminoglycoside 3'-phosphotransferase AphA1-IAB B0VD92 B0VD92_ACIBY Acinetobacter baumannii 3 0.7670
Aurora kinase A O14965 AURKA_HUMAN Homo sapiens 3 0.7665
Cyclin-dependent kinase 2 P24941 CDK2_HUMAN Homo sapiens 3 0.7665
Cyclin-dependent kinase 2 P24941 CDK2_HUMAN Homo sapiens 3 0.7665
Aurora kinase A O14965 AURKA_HUMAN Homo sapiens 3 0.7665
Cytochrome P450 S6BVH1 S6BVH1_RHOER Rhodococcus erythropolis 3 0.7664
Cytochrome P450 S6BVH1 S6BVH1_RHOER Rhodococcus erythropolis 3 0.7664
Albumin P02768 ALBU_HUMAN Homo sapiens 4 0.7656
Ephrin type-A receptor 2 P29317 EPHA2_HUMAN Homo sapiens 3 0.7656
Ephrin type-A receptor 2 P29317 EPHA2_HUMAN Homo sapiens 3 0.7656
Albumin P02768 ALBU_HUMAN Homo sapiens 4 0.7656
Decaprenylphosphoryl-beta-D-ribose oxidase I6X8C4 I6X8C4_MYCTU Mycobacterium tuberculosis 3 0.7654
Decaprenylphosphoryl-beta-D-ribose oxidase I6X8C4 I6X8C4_MYCTU Mycobacterium tuberculosis 3 0.7654
Aldo-keto reductase family 1 member D1 P51857 AK1D1_HUMAN Homo sapiens 2 0.7652
Aldo-keto reductase family 1 member D1 P51857 AK1D1_HUMAN Homo sapiens 2 0.7652
Beta-secretase 1 P56817 BACE1_HUMAN Homo sapiens 4 0.7649
Beta-secretase 1 P56817 BACE1_HUMAN Homo sapiens 4 0.7649
Prothrombin P00734 THRB_HUMAN Homo sapiens 3 0.7640
Prothrombin P00734 THRB_HUMAN Homo sapiens 3 0.7640
cGMP-dependent 3',5'-cyclic phosphodiesterase O00408 PDE2A_HUMAN Homo sapiens 3 0.7638
cGMP-dependent 3',5'-cyclic phosphodiesterase O00408 PDE2A_HUMAN Homo sapiens 3 0.7638
Serine/threonine-protein kinase pim-1 P11309 PIM1_HUMAN Homo sapiens 3 0.7636
Serine/threonine-protein kinase pim-1 P11309 PIM1_HUMAN Homo sapiens 3 0.7636
Putative S-adenosyl-L-methionine-dependent methyltransferase ML2640 Q9CCZ4 Y2640_MYCLE Mycobacterium leprae 3 0.7632
Putative S-adenosyl-L-methionine-dependent methyltransferase ML2640 Q9CCZ4 Y2640_MYCLE Mycobacterium leprae 3 0.7632
Aldo-keto reductase family 1 member C2 P52895 AK1C2_HUMAN Homo sapiens 2 0.7631
Aldo-keto reductase family 1 member C2 P52895 AK1C2_HUMAN Homo sapiens 2 0.7631
Chemotaxis protein CheA Q56310 CHEA_THEMA Thermotoga maritima 4 0.7630
Chemotaxis protein CheA Q56310 CHEA_THEMA Thermotoga maritima 4 0.7630
Pancreatic alpha-amylase P04746 AMYP_HUMAN Homo sapiens 3 0.7624
Pancreatic alpha-amylase P04746 AMYP_HUMAN Homo sapiens 3 0.7624
Beta-lactoglobulin P02754 LACB_BOVIN Bos taurus 3 0.7623
Beta-lactoglobulin P02754 LACB_BOVIN Bos taurus 3 0.7623
Thermolysin P00800 THER_BACTH Bacillus thermoproteolyticus 3 0.7608
Thermolysin P00800 THER_BACTH Bacillus thermoproteolyticus 3 0.7608
Stromelysin-1 P08254 MMP3_HUMAN Homo sapiens 3 0.7606
Stromelysin-1 P08254 MMP3_HUMAN Homo sapiens 3 0.7606
Phospholipase A2, major isoenzyme P00592 PA21B_PIG Sus scrofa 4 0.7604
Carbonyl reductase [NADPH] 1 P16152 CBR1_HUMAN Homo sapiens 3 0.7604
Phospholipase A2, major isoenzyme P00592 PA21B_PIG Sus scrofa 4 0.7604
Carbonyl reductase [NADPH] 1 P16152 CBR1_HUMAN Homo sapiens 3 0.7604
Thymidylate synthase P00469 TYSY_LACCA Lacticaseibacillus casei 3 0.7597
Thymidylate synthase P00469 TYSY_LACCA Lacticaseibacillus casei 3 0.7597
Aldo-keto reductase family 1 member D1 P51857 AK1D1_HUMAN Homo sapiens 2 0.7593
Aldo-keto reductase family 1 member D1 P51857 AK1D1_HUMAN Homo sapiens 2 0.7593
Soluble acetylcholine receptor Q8WSF8 Q8WSF8_APLCA Aplysia californica 3 0.7592
Soluble acetylcholine receptor Q8WSF8 Q8WSF8_APLCA Aplysia californica 3 0.7592
Enoyl-[acyl-carrier-protein] reductase [NADH] P9WGR1 INHA_MYCTU Mycobacterium tuberculosis 3 0.7590
Enoyl-[acyl-carrier-protein] reductase [NADH] P9WGR1 INHA_MYCTU Mycobacterium tuberculosis 3 0.7590
Aldo-keto reductase family 1 member C2 P52895 AK1C2_HUMAN Homo sapiens 2 0.7585
Aldo-keto reductase family 1 member C2 P52895 AK1C2_HUMAN Homo sapiens 2 0.7585
Tetracycline repressor protein class H P51561 TETR8_PASMD Pasteurella multocida 3 0.7583
Tetracycline repressor protein class H P51561 TETR8_PASMD Pasteurella multocida 3 0.7583
Glycogen synthase kinase-3 beta P49841 GSK3B_HUMAN Homo sapiens 3 0.7577
Glycogen synthase kinase-3 beta P49841 GSK3B_HUMAN Homo sapiens 3 0.7577
Methylmalonyl-CoA decarboxylase P52045 SCPB_ECOLI Escherichia coli 3 0.7570
Methylmalonyl-CoA decarboxylase P52045 SCPB_ECOLI Escherichia coli 3 0.7570
Endoplasmin P41148 ENPL_CANLF Canis lupus familiaris 3 0.7564
Endoplasmin P41148 ENPL_CANLF Canis lupus familiaris 3 0.7564
Dihydrofolate reductase P0ABQ4 DYR_ECOLI Escherichia coli 4 0.7563
Dihydrofolate reductase P0ABQ4 DYR_ECOLI Escherichia coli 4 0.7563
Soluble acetylcholine receptor Q8WSF8 Q8WSF8_APLCA Aplysia californica 3 0.7561
Soluble acetylcholine receptor Q8WSF8 Q8WSF8_APLCA Aplysia californica 3 0.7561
Diphtheria toxin P00588 DTX_CORBE Corynephage beta 3 0.7551
Diphtheria toxin P00588 DTX_CORBE Corynephage beta 3 0.7551
Queuine tRNA-ribosyltransferase P28720 TGT_ZYMMO Zymomonas mobilis subsp. mobilis 3 0.7548
Queuine tRNA-ribosyltransferase P28720 TGT_ZYMMO Zymomonas mobilis subsp. mobilis 3 0.7548
Fatty acid-binding protein, liver P80226 FABPL_CHICK Gallus gallus 3 0.7541
Fatty acid-binding protein, liver P80226 FABPL_CHICK Gallus gallus 3 0.7541
Aldo-keto reductase family 1 member C1 Q04828 AK1C1_HUMAN Homo sapiens 2 0.7533
Aldo-keto reductase family 1 member C1 Q04828 AK1C1_HUMAN Homo sapiens 2 0.7533
Steroid Delta-isomerase P07445 SDIS_PSEPU Pseudomonas putida 2 0.7527
Steroid Delta-isomerase P07445 SDIS_PSEPU Pseudomonas putida 2 0.7527
Bromodomain-containing protein 2 P25440 BRD2_HUMAN Homo sapiens 4 0.7524
Bromodomain-containing protein 2 P25440 BRD2_HUMAN Homo sapiens 4 0.7524
Queuine tRNA-ribosyltransferase P28720 TGT_ZYMMO Zymomonas mobilis subsp. mobilis 3 0.7523
Queuine tRNA-ribosyltransferase P28720 TGT_ZYMMO Zymomonas mobilis subsp. mobilis 3 0.7523
Cyclin-dependent kinase 9 P50750 CDK9_HUMAN Homo sapiens 3 0.7514
Cyclin-dependent kinase 9 P50750 CDK9_HUMAN Homo sapiens 3 0.7514
Epidermal growth factor receptor P00533 EGFR_HUMAN Homo sapiens 3 0.7513
Epidermal growth factor receptor P00533 EGFR_HUMAN Homo sapiens 3 0.7513
Dihydrofolate reductase P00374 DYR_HUMAN Homo sapiens 3 0.7511
Vitamin D(3) 25-hydroxylase C4B644 CPVDH_PSEAH Pseudonocardia autotrophica 3 0.7511
Dihydrofolate reductase P00374 DYR_HUMAN Homo sapiens 3 0.7511
Vitamin D(3) 25-hydroxylase C4B644 CPVDH_PSEAH Pseudonocardia autotrophica 3 0.7511
tyrosine--tRNA ligase Q4QFJ7 Q4QFJ7_LEIMA Leishmania major 3 0.7506
tyrosine--tRNA ligase Q4QFJ7 Q4QFJ7_LEIMA Leishmania major 3 0.7506
Retinol-binding protein 4 P18902 RET4_BOVIN Bos taurus 4 0.7497
Retinol-binding protein 4 P18902 RET4_BOVIN Bos taurus 4 0.7497
Poly [ADP-ribose] polymerase 1 P09874 PARP1_HUMAN Homo sapiens 3 0.7494
Poly [ADP-ribose] polymerase 1 P09874 PARP1_HUMAN Homo sapiens 3 0.7494
Endoplasmin P41148 ENPL_CANLF Canis lupus familiaris 3 0.7492
Endoplasmin P41148 ENPL_CANLF Canis lupus familiaris 3 0.7492
Phenylalanine-4-hydroxylase P00439 PH4H_HUMAN Homo sapiens 3 0.7490
Phenylalanine-4-hydroxylase P00439 PH4H_HUMAN Homo sapiens 3 0.7490
Heat shock protein HSP 90-beta P08238 HS90B_HUMAN Homo sapiens 3 0.7487
Heat shock protein HSP 90-beta P08238 HS90B_HUMAN Homo sapiens 3 0.7487
Mitogen-activated protein kinase 14 Q16539 MK14_HUMAN Homo sapiens 4 0.7482
Mitogen-activated protein kinase 14 Q16539 MK14_HUMAN Homo sapiens 4 0.7482
Dihydrofolate reductase P00374 DYR_HUMAN Homo sapiens 3 0.7472
Dihydrofolate reductase P00374 DYR_HUMAN Homo sapiens 3 0.7472
Cytosolic purine 5'-nucleotidase P49902 5NTC_HUMAN Homo sapiens 2 0.7471
Cytosolic purine 5'-nucleotidase P49902 5NTC_HUMAN Homo sapiens 2 0.7471
Mitogen-activated protein kinase 1 P28482 MK01_HUMAN Homo sapiens 3 0.7465
Nuclear receptor subfamily 1 group I member 2 O75469 NR1I2_HUMAN Homo sapiens 3 0.7465
Mycinamicin III 3''-O-methyltransferase Q49492 MYCF_MICGR Micromonospora griseorubida 3 0.7465
Mitogen-activated protein kinase 1 P28482 MK01_HUMAN Homo sapiens 3 0.7465
Mycinamicin III 3''-O-methyltransferase Q49492 MYCF_MICGR Micromonospora griseorubida 3 0.7465
Nuclear receptor subfamily 1 group I member 2 O75469 NR1I2_HUMAN Homo sapiens 3 0.7465
Beta-lactamase Q9L5C8 Q9L5C8_ECOLX Escherichia coli 3 0.7463
Beta-lactamase Q9L5C8 Q9L5C8_ECOLX Escherichia coli 3 0.7463
HLA class I histocompatibility antigen, B alpha chain P01889 HLAB_HUMAN Homo sapiens 3 0.7454
HLA class I histocompatibility antigen, B alpha chain P01889 HLAB_HUMAN Homo sapiens 3 0.7454
Genome polyprotein Q2YHF0 POLG_DEN4T Dengue virus type 4 3 0.7448
Genome polyprotein Q2YHF0 POLG_DEN4T Dengue virus type 4 3 0.7448
3',5'-cyclic-AMP phosphodiesterase 4D Q08499 PDE4D_HUMAN Homo sapiens 3 0.7448
3',5'-cyclic-AMP phosphodiesterase 4D Q08499 PDE4D_HUMAN Homo sapiens 3 0.7448
Riboflavin synthase P0AFU8 RISA_ECOLI Escherichia coli 3 0.7443
Riboflavin synthase P0AFU8 RISA_ECOLI Escherichia coli 3 0.7443
Bromodomain-containing protein 4 O60885 BRD4_HUMAN Homo sapiens 4 0.7443
Bromodomain-containing protein 4 O60885 BRD4_HUMAN Homo sapiens 4 0.7443
Nitric oxide synthase, inducible P29477 NOS2_MOUSE Mus musculus 3 0.7441
Nitric oxide synthase, inducible P29477 NOS2_MOUSE Mus musculus 3 0.7441
Acetylcholinesterase P21836 ACES_MOUSE Mus musculus 2 0.7440
Acetylcholinesterase P21836 ACES_MOUSE Mus musculus 2 0.7440
Cellular retinol-binding protein type II Q8UVG6 Q8UVG6_DANRE Danio rerio 3 0.7439
Cellular retinol-binding protein type II Q8UVG6 Q8UVG6_DANRE Danio rerio 3 0.7439
Tetracycline repressor protein class D P0ACT4 TETR4_ECOLX Escherichia coli 3 0.7438
Gag-Pol polyprotein P12497 POL_HV1N5 Human immunodeficiency virus type 1 group M subtype B 3 0.7438
Tetracycline repressor protein class D P0ACT4 TETR4_ECOLX Escherichia coli 3 0.7438
Gag-Pol polyprotein P12497 POL_HV1N5 Human immunodeficiency virus type 1 group M subtype B 3 0.7438
Calmodulin-domain protein kinase 1, putative A3FQ16 A3FQ16_CRYPI Cryptosporidium parvum 3 0.7436
Lactotransferrin P24627 TRFL_BOVIN Bos taurus 2 0.7436
Lactotransferrin P24627 TRFL_BOVIN Bos taurus 2 0.7436
Calmodulin-domain protein kinase 1, putative A3FQ16 A3FQ16_CRYPI Cryptosporidium parvum 3 0.7436
Purine nucleoside phosphorylase DeoD-type O34925 DEOD_BACSU Bacillus subtilis 3 0.7435
Serpin domain-containing protein H0ZQY2 H0ZQY2_TAEGU Taeniopygia guttata 3 0.7435
Purine nucleoside phosphorylase DeoD-type O34925 DEOD_BACSU Bacillus subtilis 3 0.7435
Serpin domain-containing protein H0ZQY2 H0ZQY2_TAEGU Taeniopygia guttata 3 0.7435
Protein BRASSINOSTEROID INSENSITIVE 1 O22476 BRI1_ARATH Arabidopsis thaliana 3 0.7432
Protein BRASSINOSTEROID INSENSITIVE 1 O22476 BRI1_ARATH Arabidopsis thaliana 3 0.7432
Thymidylate synthase P00469 TYSY_LACCA Lacticaseibacillus casei 4 0.7428
Thymidylate synthase P00469 TYSY_LACCA Lacticaseibacillus casei 4 0.7428
Putative pteridine reductase 2 Q8I814 Q8I814_TRYCR Trypanosoma cruzi 4 0.7425
Putative pteridine reductase 2 Q8I814 Q8I814_TRYCR Trypanosoma cruzi 4 0.7425
Endoplasmin P41148 ENPL_CANLF Canis lupus familiaris 3 0.7424
Endoplasmin P41148 ENPL_CANLF Canis lupus familiaris 3 0.7424
Flavin reductase like domain-containing protein Q4UKE8 Q4UKE8_RICFE Rickettsia felis 3 0.7423
Flavin reductase like domain-containing protein Q4UKE8 Q4UKE8_RICFE Rickettsia felis 3 0.7423
Major pollen allergen Bet v 1-A P15494 BEV1A_BETPN Betula pendula 3 0.7415
Major pollen allergen Bet v 1-A P15494 BEV1A_BETPN Betula pendula 3 0.7415
Beta-secretase 1 P56817 BACE1_HUMAN Homo sapiens 3 0.7415
Beta-secretase 1 P56817 BACE1_HUMAN Homo sapiens 3 0.7415
MAP kinase-activated protein kinase 2 P49137 MAPK2_HUMAN Homo sapiens 4 0.7410
MAP kinase-activated protein kinase 2 P49137 MAPK2_HUMAN Homo sapiens 4 0.7410
Aurora kinase A O14965 AURKA_HUMAN Homo sapiens 3 0.7407
Gag-Pol polyprotein P04584 POL_HV2RO Human immunodeficiency virus type 2 subtype A 3 0.7407
Gag-Pol polyprotein P04584 POL_HV2RO Human immunodeficiency virus type 2 subtype A 3 0.7407
Aurora kinase A O14965 AURKA_HUMAN Homo sapiens 3 0.7407
Beta-galactoside-specific lectin 1 P81446 ML1_VISAL Viscum album 3 0.7406
Beta-galactoside-specific lectin 1 P81446 ML1_VISAL Viscum album 3 0.7406
Pentaerythritol tetranitrate reductase P71278 P71278_ENTCL Enterobacter cloacae 2 0.7405
Steroid 17-alpha-hydroxylase/17,20 lyase P05093 CP17A_HUMAN Homo sapiens 3 0.7405
Pentaerythritol tetranitrate reductase P71278 P71278_ENTCL Enterobacter cloacae 2 0.7405
Steroid 17-alpha-hydroxylase/17,20 lyase P05093 CP17A_HUMAN Homo sapiens 3 0.7405
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 P04191 AT2A1_RABIT Oryctolagus cuniculus 3 0.7404
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 P04191 AT2A1_RABIT Oryctolagus cuniculus 3 0.7404
UDP-galactopyranose mutase Q48485 GLF1_KLEPN Klebsiella pneumoniae 3 0.7403
UDP-galactopyranose mutase Q48485 GLF1_KLEPN Klebsiella pneumoniae 3 0.7403
3-hydroxyanthranilate 3,4-dioxygenase Q1LCS4 3HAO_CUPMC Cupriavidus metallidurans 2 0.7396
3-hydroxyanthranilate 3,4-dioxygenase Q1LCS4 3HAO_CUPMC Cupriavidus metallidurans 2 0.7396
Aldo-keto reductase family 1 member D1 P51857 AK1D1_HUMAN Homo sapiens 2 0.7396
Aldo-keto reductase family 1 member D1 P51857 AK1D1_HUMAN Homo sapiens 2 0.7396
Iron-uptake system-binding protein P40409 FEUA_BACSU Bacillus subtilis 4 0.7395
Iron-uptake system-binding protein P40409 FEUA_BACSU Bacillus subtilis 4 0.7395
Bromodomain-containing protein 2 P25440 BRD2_HUMAN Homo sapiens 4 0.7393
Bromodomain-containing protein 2 P25440 BRD2_HUMAN Homo sapiens 4 0.7393
Ras-related protein Ral-B P11234 RALB_HUMAN Homo sapiens 3 0.7391
Ras-related protein Ral-B P11234 RALB_HUMAN Homo sapiens 3 0.7391
HTH-type transcriptional repressor PurR P0ACP7 PURR_ECOLI Escherichia coli 3 0.7383
HTH-type transcriptional repressor PurR P0ACP7 PURR_ECOLI Escherichia coli 3 0.7383
Glucose-1-phosphate thymidylyltransferase Q9HU22 Q9HU22_PSEAE Pseudomonas aeruginosa 3 0.7382
Glucose-1-phosphate thymidylyltransferase Q9HU22 Q9HU22_PSEAE Pseudomonas aeruginosa 3 0.7382
Thymidylate synthase P00469 TYSY_LACCA Lacticaseibacillus casei 2 0.7381
Thymidylate synthase P00469 TYSY_LACCA Lacticaseibacillus casei 2 0.7381
Proto-oncogene tyrosine-protein kinase receptor Ret P07949 RET_HUMAN Homo sapiens 3 0.7380
Proto-oncogene tyrosine-protein kinase receptor Ret P07949 RET_HUMAN Homo sapiens 3 0.7380
Cyclin-dependent kinase 2 P24941 CDK2_HUMAN Homo sapiens 3 0.7378
Cyclin-dependent kinase 2 P24941 CDK2_HUMAN Homo sapiens 3 0.7378
Heat shock protein HSP 90-alpha P07900 HS90A_HUMAN Homo sapiens 3 0.7375
Heat shock protein HSP 90-alpha P07900 HS90A_HUMAN Homo sapiens 3 0.7375
ATP-dependent molecular chaperone HSP82 P02829 HSP82_YEAST Saccharomyces cerevisiae 3 0.7359
ATP-dependent molecular chaperone HSP82 P02829 HSP82_YEAST Saccharomyces cerevisiae 3 0.7359
Aldo-keto reductase family 1 member D1 P51857 AK1D1_HUMAN Homo sapiens 2 0.7352
Aldo-keto reductase family 1 member D1 P51857 AK1D1_HUMAN Homo sapiens 2 0.7352
Tyrosine-protein kinase JAK2 O60674 JAK2_HUMAN Homo sapiens 3 0.7348
Threonine--tRNA ligase P0A8M3 SYT_ECOLI Escherichia coli 3 0.7348
Tyrosine-protein kinase JAK2 O60674 JAK2_HUMAN Homo sapiens 3 0.7348
Threonine--tRNA ligase P0A8M3 SYT_ECOLI Escherichia coli 3 0.7348
Endothiapepsin P11838 CARP_CRYPA Cryphonectria parasitica 4 0.7347
Endothiapepsin P11838 CARP_CRYPA Cryphonectria parasitica 4 0.7347
Isoflavone-7-O-methyltransferase 8 O24529 7OMT8_MEDSA Medicago sativa 5 0.7340
Mitochondrial poly(A) polymerase F1NBW0 F1NBW0_CHICK Gallus gallus 2 0.7340
Mitochondrial poly(A) polymerase F1NBW0 F1NBW0_CHICK Gallus gallus 2 0.7340
Isoflavone-7-O-methyltransferase 8 O24529 7OMT8_MEDSA Medicago sativa 5 0.7340
Thymidylate synthase P0A884 TYSY_ECOLI Escherichia coli 4 0.7335
Thymidylate synthase P0A884 TYSY_ECOLI Escherichia coli 4 0.7335
Casein kinase II subunit alpha P68400 CSK21_HUMAN Homo sapiens 3 0.7332
Casein kinase II subunit alpha P68400 CSK21_HUMAN Homo sapiens 3 0.7332
Proto-oncogene tyrosine-protein kinase Src P00523 SRC_CHICK Gallus gallus 3 0.7331
Proto-oncogene tyrosine-protein kinase Src P00523 SRC_CHICK Gallus gallus 3 0.7331
TGF-beta-activated kinase 1 and MAP3K7-binding protein 1 Q15750 TAB1_HUMAN Homo sapiens 3 0.7329
Poly [ADP-ribose] polymerase tankyrase-2 Q9H2K2 TNKS2_HUMAN Homo sapiens 3 0.7329
Poly [ADP-ribose] polymerase tankyrase-2 Q9H2K2 TNKS2_HUMAN Homo sapiens 3 0.7329
TGF-beta-activated kinase 1 and MAP3K7-binding protein 1 Q15750 TAB1_HUMAN Homo sapiens 3 0.7329
Acetylcholinesterase P04058 ACES_TETCF Tetronarce californica 3 0.7327
Acetylcholinesterase P04058 ACES_TETCF Tetronarce californica 3 0.7327
High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A O76083 PDE9A_HUMAN Homo sapiens 3 0.7324
Mitogen-activated protein kinase 1 P63086 MK01_RAT Rattus norvegicus 3 0.7324
Mitogen-activated protein kinase 1 P63086 MK01_RAT Rattus norvegicus 3 0.7324
High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A O76083 PDE9A_HUMAN Homo sapiens 3 0.7324
Photosynthetic reaction center cytochrome c subunit P07173 CYCR_BLAVI Blastochloris viridis 2 0.7323
Photosynthetic reaction center cytochrome c subunit P07173 CYCR_BLAVI Blastochloris viridis 2 0.7323
DNA gyrase subunit A P0AES5 GYRA_SHIFL Shigella flexneri 3 0.7322
HTH-type transcriptional repressor PurR P0ACP7 PURR_ECOLI Escherichia coli 3 0.7322
DNA gyrase subunit A P0AES5 GYRA_SHIFL Shigella flexneri 3 0.7322
HTH-type transcriptional repressor PurR P0ACP7 PURR_ECOLI Escherichia coli 3 0.7322
Death-associated protein kinase 1 P53355 DAPK1_HUMAN Homo sapiens 3 0.7321
Death-associated protein kinase 1 P53355 DAPK1_HUMAN Homo sapiens 3 0.7321
Adenosine monophosphate-protein transferase Q8ZVF7 Q8ZVF7_PYRAE Pyrobaculum aerophilum 3 0.7311
Adenosine monophosphate-protein transferase Q8ZVF7 Q8ZVF7_PYRAE Pyrobaculum aerophilum 3 0.7311
Thymidylate synthase P0A884 TYSY_ECOLI Escherichia coli 3 0.7309
Thymidylate synthase P0A884 TYSY_ECOLI Escherichia coli 3 0.7309
Retinol-binding protein 1 P02696 RET1_RAT Rattus norvegicus 3 0.7306
Retinol-binding protein 1 P02696 RET1_RAT Rattus norvegicus 3 0.7306
Beta-1 adrenergic receptor P07700 ADRB1_MELGA Meleagris gallopavo 3 0.7305
Beta-1 adrenergic receptor P07700 ADRB1_MELGA Meleagris gallopavo 3 0.7305
Basic phospholipase A2 VRV-PL-VIIIa P59071 PA2B8_DABRR Daboia russelii 2 0.7303
Basic phospholipase A2 VRV-PL-VIIIa P59071 PA2B8_DABRR Daboia russelii 2 0.7303
Cathepsin S P25774 CATS_HUMAN Homo sapiens 3 0.7298
Cathepsin S P25774 CATS_HUMAN Homo sapiens 3 0.7298
Acyl-CoA:acyl-CoA alkyltransferase Q8PDX2 OLEA_XANCP Xanthomonas campestris pv. campestris 3 0.7295
Acyl-CoA:acyl-CoA alkyltransferase Q8PDX2 OLEA_XANCP Xanthomonas campestris pv. campestris 3 0.7295
Heat shock protein HSP 90-alpha P07900 HS90A_HUMAN Homo sapiens 3 0.7294
Heat shock protein HSP 90-alpha P07900 HS90A_HUMAN Homo sapiens 3 0.7294
Cytochrome P450 monooxygenase Q5YNS8 Q5YNS8_NOCFA Nocardia farcinica 2 0.7289
Cytochrome P450 monooxygenase Q5YNS8 Q5YNS8_NOCFA Nocardia farcinica 2 0.7289
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 Q9Y3Q4 HCN4_HUMAN Homo sapiens 3 0.7288
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 Q9Y3Q4 HCN4_HUMAN Homo sapiens 3 0.7288
Formylmethanofuran--tetrahydromethanopterin formyltransferase Q49610 FTR_METKA Methanopyrus kandleri 3 0.7285
Formylmethanofuran--tetrahydromethanopterin formyltransferase Q49610 FTR_METKA Methanopyrus kandleri 3 0.7285
Protein ppBat Q8A8A4 Q8A8A4_BACTN Bacteroides thetaiotaomicron VPI-5482 3 0.7279
Protein ppBat Q8A8A4 Q8A8A4_BACTN Bacteroides thetaiotaomicron VPI-5482 3 0.7279
Camphor 5-monooxygenase P00183 CPXA_PSEPU Pseudomonas putida 3 0.7276
Camphor 5-monooxygenase P00183 CPXA_PSEPU Pseudomonas putida 3 0.7276
UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--LD-lysine ligase Q9WY79 MURE_THEMA Thermotoga maritima 3 0.7275
UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--LD-lysine ligase Q9WY79 MURE_THEMA Thermotoga maritima 3 0.7275
Isoflavone 4'-O-methyltransferase Q29U70 I4OMT_MEDTR Medicago truncatula 3 0.7271
Isoflavone 4'-O-methyltransferase Q29U70 I4OMT_MEDTR Medicago truncatula 3 0.7271
Lactoylglutathione lyase Q9CPU0 LGUL_MOUSE Mus musculus 2 0.7269
Lactoylglutathione lyase Q9CPU0 LGUL_MOUSE Mus musculus 2 0.7269
Thymidylate synthase P00469 TYSY_LACCA Lacticaseibacillus casei 3 0.7260
Thymidylate synthase P00469 TYSY_LACCA Lacticaseibacillus casei 3 0.7260
Serine hydroxymethyltransferase Q7SIB6 Q7SIB6_GEOSE Geobacillus stearothermophilus 3 0.7260
Serine hydroxymethyltransferase Q7SIB6 Q7SIB6_GEOSE Geobacillus stearothermophilus 3 0.7260
Fibroblast growth factor receptor 2 P21802 FGFR2_HUMAN Homo sapiens 3 0.7257
Fibroblast growth factor receptor 2 P21802 FGFR2_HUMAN Homo sapiens 3 0.7257
Serine/threonine-protein kinase VRK1 Q99986 VRK1_HUMAN Homo sapiens 3 0.7254
Serine/threonine-protein kinase VRK1 Q99986 VRK1_HUMAN Homo sapiens 3 0.7254
Acetyl-CoA carboxylase Q00955 ACAC_YEAST Saccharomyces cerevisiae 3 0.7252
Acetyl-CoA carboxylase Q00955 ACAC_YEAST Saccharomyces cerevisiae 3 0.7252
Beta-elicitin cryptogein P15570 ELIB_PHYCR Phytophthora cryptogea 3 0.7248
Lactotransferrin P24627 TRFL_BOVIN Bos taurus 3 0.7248
Beta-elicitin cryptogein P15570 ELIB_PHYCR Phytophthora cryptogea 3 0.7248
Lactotransferrin P24627 TRFL_BOVIN Bos taurus 3 0.7248
DNA topoisomerase 1 P06612 TOP1_ECOLI Escherichia coli 3 0.7245
DNA topoisomerase 1 P06612 TOP1_ECOLI Escherichia coli 3 0.7245
Bromodomain adjacent to zinc finger domain protein 2B Q9UIF8 BAZ2B_HUMAN Homo sapiens 3 0.7244
Bromodomain adjacent to zinc finger domain protein 2B Q9UIF8 BAZ2B_HUMAN Homo sapiens 3 0.7244
Dihydrofolate reductase P0A017 DYR_STAAU Staphylococcus aureus 4 0.7243
Dihydrofolate reductase P0A017 DYR_STAAU Staphylococcus aureus 4 0.7243
Mitogen-activated protein kinase kinase kinase 7 O43318 M3K7_HUMAN Homo sapiens 3 0.7241
Mitogen-activated protein kinase kinase kinase 7 O43318 M3K7_HUMAN Homo sapiens 3 0.7241
Retinol-binding protein 4 P18902 RET4_BOVIN Bos taurus 4 0.7241
Retinol-binding protein 4 P18902 RET4_BOVIN Bos taurus 4 0.7241
Cyclin-dependent kinase 9 P50750 CDK9_HUMAN Homo sapiens 3 0.7238
Cyclin-dependent kinase 9 P50750 CDK9_HUMAN Homo sapiens 3 0.7238
Endoplasmin P41148 ENPL_CANLF Canis lupus familiaris 3 0.7237
Endoplasmin P41148 ENPL_CANLF Canis lupus familiaris 3 0.7237
Heat shock protein HSP 90-alpha P07900 HS90A_HUMAN Homo sapiens 3 0.7234
Heat shock protein HSP 90-alpha P07900 HS90A_HUMAN Homo sapiens 3 0.7234
Ethylene receptor 1 P49333 ETR1_ARATH Arabidopsis thaliana 3 0.7233
Ethylene receptor 1 P49333 ETR1_ARATH Arabidopsis thaliana 3 0.7233
3',5'-cyclic-AMP phosphodiesterase 4D Q08499 PDE4D_HUMAN Homo sapiens 4 0.7226
3',5'-cyclic-AMP phosphodiesterase 4D Q08499 PDE4D_HUMAN Homo sapiens 4 0.7226
Camphor 5-monooxygenase P00183 CPXA_PSEPU Pseudomonas putida 4 0.7225
Camphor 5-monooxygenase P00183 CPXA_PSEPU Pseudomonas putida 4 0.7225
Heat shock protein HSP 90-alpha P07900 HS90A_HUMAN Homo sapiens 3 0.7221
Heat shock protein HSP 90-alpha P07900 HS90A_HUMAN Homo sapiens 3 0.7221
Ribonuclease TTHA0252 Q5SLP1 RNSE_THET8 Thermus thermophilus 3 0.7221
Ribonuclease TTHA0252 Q5SLP1 RNSE_THET8 Thermus thermophilus 3 0.7221
4-hydroxyphenylacetate 3-monooxygenase Q8YHT7 Q8YHT7_BRUME Brucella melitensis biotype 1 2 0.7208
Vitamin D3 dihydroxylase P18326 CPXE_STRGO Streptomyces griseolus 3 0.7208
Vitamin D3 dihydroxylase P18326 CPXE_STRGO Streptomyces griseolus 3 0.7208
4-hydroxyphenylacetate 3-monooxygenase Q8YHT7 Q8YHT7_BRUME Brucella melitensis biotype 1 2 0.7208
Beta-1 adrenergic receptor P07700 ADRB1_MELGA Meleagris gallopavo 3 0.7207
Beta-1 adrenergic receptor P07700 ADRB1_MELGA Meleagris gallopavo 3 0.7207
Chloramphenicol 3-O phosphotransferase Q56148 CPT_STRVP Streptomyces venezuelae 3 0.7205
Chloramphenicol 3-O phosphotransferase Q56148 CPT_STRVP Streptomyces venezuelae 3 0.7205
Metallo-beta-lactamase type 2 C7C422 BLAN1_KLEPN Klebsiella pneumoniae 2 0.7205
Metallo-beta-lactamase type 2 C7C422 BLAN1_KLEPN Klebsiella pneumoniae 2 0.7205
cGMP-specific 3',5'-cyclic phosphodiesterase O76074 PDE5A_HUMAN Homo sapiens 3 0.7201
cGMP-specific 3',5'-cyclic phosphodiesterase O76074 PDE5A_HUMAN Homo sapiens 3 0.7201
Mitogen-activated protein kinase 14 Q16539 MK14_HUMAN Homo sapiens 4 0.7199
Mitogen-activated protein kinase 14 Q16539 MK14_HUMAN Homo sapiens 4 0.7199
Bifunctional dihydrofolate reductase-thymidylate synthase Q27793 DRTS_TRYCR Trypanosoma cruzi 3 0.7197
Bifunctional dihydrofolate reductase-thymidylate synthase Q27793 DRTS_TRYCR Trypanosoma cruzi 3 0.7197
Cyclic GMP-AMP synthase Q8C6L5 CGAS_MOUSE Mus musculus 3 0.7196
Cyclic GMP-AMP synthase Q8C6L5 CGAS_MOUSE Mus musculus 3 0.7196
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform O02697 PK3CG_PIG Sus scrofa 4 0.7192
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform O02697 PK3CG_PIG Sus scrofa 4 0.7192
Fibroblast growth factor receptor 2 P21802 FGFR2_HUMAN Homo sapiens 3 0.7191
Fibroblast growth factor receptor 2 P21802 FGFR2_HUMAN Homo sapiens 3 0.7191
Methionine aminopeptidase P0AE18 MAP1_ECOLI Escherichia coli 3 0.7186
Methionine aminopeptidase P0AE18 MAP1_ECOLI Escherichia coli 3 0.7186
Sulfotransferase 2A1 Q06520 ST2A1_HUMAN Homo sapiens 2 0.7181
Sulfotransferase 2A1 Q06520 ST2A1_HUMAN Homo sapiens 2 0.7181
Gag-Pol polyprotein P04584 POL_HV2RO Human immunodeficiency virus type 2 subtype A 3 0.7180
Gag-Pol polyprotein P04584 POL_HV2RO Human immunodeficiency virus type 2 subtype A 3 0.7180
Nitric oxide synthase, inducible P29477 NOS2_MOUSE Mus musculus 3 0.7179
Ephrin type-B receptor 2 P54763 EPHB2_MOUSE Mus musculus 3 0.7179
Nitric oxide synthase, inducible P29477 NOS2_MOUSE Mus musculus 3 0.7179
Ephrin type-B receptor 2 P54763 EPHB2_MOUSE Mus musculus 3 0.7179
Gag-Pol polyprotein P03367 POL_HV1BR Human immunodeficiency virus type 1 group M subtype B 3 0.7170
Gag-Pol polyprotein P03367 POL_HV1BR Human immunodeficiency virus type 1 group M subtype B 3 0.7170
Methionine aminopeptidase 2 P50579 MAP2_HUMAN Homo sapiens 3 0.7168
Methionine aminopeptidase 2 P50579 MAP2_HUMAN Homo sapiens 3 0.7168
Seminal ribonuclease P00669 RNS_BOVIN Bos taurus 3 0.7164
Beta-galactoside-specific lectin 4 Q6ITZ3 ML4_VISAL Viscum album 2 0.7164
Seminal ribonuclease P00669 RNS_BOVIN Bos taurus 3 0.7164
Beta-galactoside-specific lectin 4 Q6ITZ3 ML4_VISAL Viscum album 2 0.7164
Integrin alpha-IIb P08514 ITA2B_HUMAN Homo sapiens 3 0.7161
Integrin alpha-IIb P08514 ITA2B_HUMAN Homo sapiens 3 0.7161
Bifunctional epoxide hydrolase 2 P34913 HYES_HUMAN Homo sapiens 4 0.7155
Bifunctional epoxide hydrolase 2 P34913 HYES_HUMAN Homo sapiens 4 0.7155
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase Q8DNV6 Q8DNV6_STRR6 Streptococcus pneumoniae 3 0.7148
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase Q8DNV6 Q8DNV6_STRR6 Streptococcus pneumoniae 3 0.7148
1-deoxy-D-xylulose 5-phosphate reductoisomerase P45568 DXR_ECOLI Escherichia coli 2 0.7146
1-deoxy-D-xylulose 5-phosphate reductoisomerase P45568 DXR_ECOLI Escherichia coli 2 0.7146
Bifunctional epoxide hydrolase 2 P34913 HYES_HUMAN Homo sapiens 2 0.7144
Bifunctional epoxide hydrolase 2 P34913 HYES_HUMAN Homo sapiens 2 0.7144
Glycogen phosphorylase, liver form P06737 PYGL_HUMAN Homo sapiens 3 0.7141
Glycogen phosphorylase, liver form P06737 PYGL_HUMAN Homo sapiens 3 0.7141
Bromodomain-containing protein 4 O60885 BRD4_HUMAN Homo sapiens 4 0.7138
Bromodomain-containing protein 4 O60885 BRD4_HUMAN Homo sapiens 4 0.7138
Pheromone-binding protein ASP1 Q9U9J6 Q9U9J6_APIME Apis mellifera 3 0.7137
Protein RecA Q59560 RECA_MYCS2 Mycolicibacterium smegmatis155) 3 0.7137
Protein RecA Q59560 RECA_MYCS2 Mycolicibacterium smegmatis155) 3 0.7137
Pheromone-binding protein ASP1 Q9U9J6 Q9U9J6_APIME Apis mellifera 3 0.7137
Valacyclovir hydrolase Q86WA6 BPHL_HUMAN Homo sapiens 3 0.7135
Valacyclovir hydrolase Q86WA6 BPHL_HUMAN Homo sapiens 3 0.7135
cGMP-dependent protein kinase 1 P00516 KGP1_BOVIN Bos taurus 3 0.7134
cGMP-dependent protein kinase 1 P00516 KGP1_BOVIN Bos taurus 3 0.7134
Heat shock protein HSP 90-alpha P07900 HS90A_HUMAN Homo sapiens 3 0.7130
Heat shock protein HSP 90-alpha P07900 HS90A_HUMAN Homo sapiens 3 0.7130
Pheromone-binding protein ASP1 Q9U9J6 Q9U9J6_APIME Apis mellifera 3 0.7130
Pheromone-binding protein ASP1 Q9U9J6 Q9U9J6_APIME Apis mellifera 3 0.7130
Endothiapepsin P11838 CARP_CRYPA Cryphonectria parasitica 3 0.7125
Endothiapepsin P11838 CARP_CRYPA Cryphonectria parasitica 3 0.7125
Heat shock protein HSP 90-alpha P07900 HS90A_HUMAN Homo sapiens 3 0.7122
Heat shock protein HSP 90-alpha P07900 HS90A_HUMAN Homo sapiens 3 0.7122
APH(2'')-Id O68183 O68183_ENTCA Enterococcus casseliflavus 3 0.7121
APH(2'')-Id O68183 O68183_ENTCA Enterococcus casseliflavus 3 0.7121
Pyruvate:ferredoxin oxidoreductase P94692 PFOR_DESAF Desulfocurvibacter africanus 3 0.7117
Homoserine dehydrogenase P31116 DHOM_YEAST Saccharomyces cerevisiae 4 0.7117
Homoserine dehydrogenase P31116 DHOM_YEAST Saccharomyces cerevisiae 4 0.7117
Pyruvate:ferredoxin oxidoreductase P94692 PFOR_DESAF Desulfocurvibacter africanus 3 0.7117
Mitogen-activated protein kinase 14 Q16539 MK14_HUMAN Homo sapiens 3 0.7116
Mitogen-activated protein kinase 14 Q16539 MK14_HUMAN Homo sapiens 3 0.7116
2',3'-cyclic-nucleotide 3'-phosphodiesterase P16330 CN37_MOUSE Mus musculus 3 0.7115
2',3'-cyclic-nucleotide 3'-phosphodiesterase P16330 CN37_MOUSE Mus musculus 3 0.7115
GCN5-related N-acetyltransferase B1YEL6 B1YEL6_EXIS2 Exiguobacterium sibiricum 3 0.7114
GCN5-related N-acetyltransferase B1YEL6 B1YEL6_EXIS2 Exiguobacterium sibiricum 3 0.7114
Cyclic GMP-AMP phosphodiesterase SMPDL3A Q92484 ASM3A_HUMAN Homo sapiens 2 0.7111
Cyclic GMP-AMP phosphodiesterase SMPDL3A Q92484 ASM3A_HUMAN Homo sapiens 2 0.7111
F420-dependent methylenetetrahydromethanopterin dehydrogenase P94951 MTD_METKA Methanopyrus kandleri 2 0.7101
F420-dependent methylenetetrahydromethanopterin dehydrogenase P94951 MTD_METKA Methanopyrus kandleri 2 0.7101
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 P04191 AT2A1_RABIT Oryctolagus cuniculus 3 0.7099
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 P04191 AT2A1_RABIT Oryctolagus cuniculus 3 0.7099
CCA-adding enzyme O28126 CCA_ARCFU Archaeoglobus fulgidus 2 0.7097
CCA-adding enzyme O28126 CCA_ARCFU Archaeoglobus fulgidus 2 0.7097
Chloramphenicol 3-O phosphotransferase Q56148 CPT_STRVP Streptomyces venezuelae 3 0.7096
Chloramphenicol 3-O phosphotransferase Q56148 CPT_STRVP Streptomyces venezuelae 3 0.7096
Queuine tRNA-ribosyltransferase P28720 TGT_ZYMMO Zymomonas mobilis subsp. mobilis 3 0.7095
Queuine tRNA-ribosyltransferase P28720 TGT_ZYMMO Zymomonas mobilis subsp. mobilis 3 0.7095
Vitamin D3 receptor P13053 VDR_RAT Rattus norvegicus 3 0.7093
Vitamin D3 receptor P13053 VDR_RAT Rattus norvegicus 3 0.7093
Genome polyprotein Q9Q6P4 POLG_WNV9 West Nile virus) 3 0.7092
Genome polyprotein Q9Q6P4 POLG_WNV9 West Nile virus) 3 0.7092
Cyclin-dependent kinase 2 P24941 CDK2_HUMAN Homo sapiens 4 0.7091
Cyclin-dependent kinase 2 P24941 CDK2_HUMAN Homo sapiens 4 0.7091
Polyribonucleotide nucleotidyltransferase A7ZS61 PNP_ECO24 Escherichia coli O139:H28 3 0.7087
Polyribonucleotide nucleotidyltransferase A7ZS61 PNP_ECO24 Escherichia coli O139:H28 3 0.7087
Tryptophan synthase alpha chain P00929 TRPA_SALTY Salmonella typhimurium 2 0.7085
Tryptophan synthase alpha chain P00929 TRPA_SALTY Salmonella typhimurium 2 0.7085
Beta-adrenergic receptor kinase 1 P25098 ARBK1_HUMAN Homo sapiens 3 0.7083
Tannase B3Y018 B3Y018_LACPN Lactiplantibacillus plantarum 3 0.7083
Beta-adrenergic receptor kinase 1 P25098 ARBK1_HUMAN Homo sapiens 3 0.7083
Tannase B3Y018 B3Y018_LACPN Lactiplantibacillus plantarum 3 0.7083
Cytosolic heat shock protein 90 Q7XJ80 Q7XJ80_HORVU Hordeum vulgare 3 0.7076
Cytosolic heat shock protein 90 Q7XJ80 Q7XJ80_HORVU Hordeum vulgare 3 0.7076
Jasmonoyl--L-amino acid synthetase JAR1 Q9SKE2 JAR1_ARATH Arabidopsis thaliana 3 0.7076
Jasmonoyl--L-amino acid synthetase JAR1 Q9SKE2 JAR1_ARATH Arabidopsis thaliana 3 0.7076
Dihydrofolate reductase P0A017 DYR_STAAU Staphylococcus aureus 3 0.7075
Dihydrofolate reductase P0A017 DYR_STAAU Staphylococcus aureus 3 0.7075
Endothiapepsin P11838 CARP_CRYPA Cryphonectria parasitica 3 0.7074
Endothiapepsin P11838 CARP_CRYPA Cryphonectria parasitica 3 0.7074
Protein BRASSINOSTEROID INSENSITIVE 1 O22476 BRI1_ARATH Arabidopsis thaliana 3 0.7073
Protein BRASSINOSTEROID INSENSITIVE 1 O22476 BRI1_ARATH Arabidopsis thaliana 3 0.7073
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 P04191 AT2A1_RABIT Oryctolagus cuniculus 3 0.7068
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 P04191 AT2A1_RABIT Oryctolagus cuniculus 3 0.7068
Actin-related protein 3 P61157 ARP3_BOVIN Bos taurus 3 0.7067
Actin-related protein 3 P61157 ARP3_BOVIN Bos taurus 3 0.7067
Flavin-dependent monooxygenase Q93L51 TETX_BACT4 Bacteroides thetaiotaomicron 4 0.7064
Flavin-dependent monooxygenase Q93L51 TETX_BACT4 Bacteroides thetaiotaomicron 4 0.7064
Eukaryotic translation initiation factor 4E type 3 Q9DBB5 IF4E3_MOUSE Mus musculus 3 0.7059
Eukaryotic translation initiation factor 4E type 3 Q9DBB5 IF4E3_MOUSE Mus musculus 3 0.7059
Prothrombin P00734 THRB_HUMAN Homo sapiens 3 0.7059
Prothrombin P00734 THRB_HUMAN Homo sapiens 3 0.7059
Chloramphenicol 3-O phosphotransferase Q56148 CPT_STRVP Streptomyces venezuelae 3 0.7057
Chloramphenicol 3-O phosphotransferase Q56148 CPT_STRVP Streptomyces venezuelae 3 0.7057
cAMP-dependent protein kinase catalytic subunit alpha P00517 KAPCA_BOVIN Bos taurus 3 0.7057
cAMP-dependent protein kinase catalytic subunit alpha P00517 KAPCA_BOVIN Bos taurus 3 0.7057
Thymidylate synthase P00469 TYSY_LACCA Lacticaseibacillus casei 3 0.7056
Uncharacterized protein Q3F0V8 Q3F0V8_BACTI Bacillus thuringiensis serovar israelensis ATCC 35646 3 0.7056
Uncharacterized protein Q3F0V8 Q3F0V8_BACTI Bacillus thuringiensis serovar israelensis ATCC 35646 3 0.7056
Thymidylate synthase P00469 TYSY_LACCA Lacticaseibacillus casei 3 0.7056
Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial Q33862 Q33862_ASCSU Ascaris suum 3 0.7054
Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial Q33862 Q33862_ASCSU Ascaris suum 3 0.7054
Calmodulin-like domain protein kinase isoenzyme gamma, related F0V9W9 F0V9W9_NEOCL Neospora caninum 3 0.7053
Calmodulin-like domain protein kinase isoenzyme gamma, related F0V9W9 F0V9W9_NEOCL Neospora caninum 3 0.7053
Retinol-binding protein 4 P18902 RET4_BOVIN Bos taurus 4 0.7051
2',3'-cyclic-nucleotide 3'-phosphodiesterase P16330 CN37_MOUSE Mus musculus 2 0.7051
2',3'-cyclic-nucleotide 3'-phosphodiesterase P16330 CN37_MOUSE Mus musculus 2 0.7051
Epidermal growth factor receptor P00533 EGFR_HUMAN Homo sapiens 3 0.7051
Retinol-binding protein 4 P18902 RET4_BOVIN Bos taurus 4 0.7051
Epidermal growth factor receptor P00533 EGFR_HUMAN Homo sapiens 3 0.7051
Genome polyprotein O92972 POLG_HCVJ4 Hepatitis C virus genotype 1b 3 0.7049
Genome polyprotein O92972 POLG_HCVJ4 Hepatitis C virus genotype 1b 3 0.7049
Beta-1 adrenergic receptor P07700 ADRB1_MELGA Meleagris gallopavo 2 0.7048
Beta-1 adrenergic receptor P07700 ADRB1_MELGA Meleagris gallopavo 2 0.7048
Renin P00797 RENI_HUMAN Homo sapiens 3 0.7047
Renin P00797 RENI_HUMAN Homo sapiens 3 0.7047
Peroxisome proliferator-activated receptor gamma P37231 PPARG_HUMAN Homo sapiens 2 0.7047
Peroxisome proliferator-activated receptor gamma P37231 PPARG_HUMAN Homo sapiens 2 0.7047
Cyclin-dependent kinase 6 Q00534 CDK6_HUMAN Homo sapiens 5 0.7046
Cyclin-dependent kinase 6 Q00534 CDK6_HUMAN Homo sapiens 5 0.7046
Histidine kinase 4 Q9C5U0 AHK4_ARATH Arabidopsis thaliana 4 0.7045
Histidine kinase 4 Q9C5U0 AHK4_ARATH Arabidopsis thaliana 4 0.7045
Acetolactate synthase, chloroplastic P17597 ILVB_ARATH Arabidopsis thaliana 2 0.7040
Acetolactate synthase, chloroplastic P17597 ILVB_ARATH Arabidopsis thaliana 2 0.7040
FMN-dependent NAD(P)H:quinone oxidoreductase 1 Q9I5F3 AZOR1_PSEAE Pseudomonas aeruginosa 2 0.7038
FMN-dependent NAD(P)H:quinone oxidoreductase 1 Q9I5F3 AZOR1_PSEAE Pseudomonas aeruginosa 2 0.7038
Carbonic anhydrase 2 P00918 CAH2_HUMAN Homo sapiens 3 0.7036
Carbonic anhydrase 2 P00918 CAH2_HUMAN Homo sapiens 3 0.7036
N-acetyltransferase domain-containing protein Q9HV14 Q9HV14_PSEAE Pseudomonas aeruginosa 3 0.7032
N-acetyltransferase domain-containing protein Q9HV14 Q9HV14_PSEAE Pseudomonas aeruginosa 3 0.7032
Thymidine kinase P0DTH5 KITH_HHV11 Human herpesvirus 1 2 0.7030
Thymidine kinase P0DTH5 KITH_HHV11 Human herpesvirus 1 2 0.7030
GCN5-related N-acetyltransferase B1YEL6 B1YEL6_EXIS2 Exiguobacterium sibiricum 3 0.7026
GCN5-related N-acetyltransferase B1YEL6 B1YEL6_EXIS2 Exiguobacterium sibiricum 3 0.7026
Phospholipase A2, major isoenzyme P00592 PA21B_PIG Sus scrofa 3 0.7020
Phospholipase A2, major isoenzyme P00592 PA21B_PIG Sus scrofa 3 0.7020
Activin receptor type-1 Q04771 ACVR1_HUMAN Homo sapiens 2 0.7018
Activin receptor type-1 Q04771 ACVR1_HUMAN Homo sapiens 2 0.7018
Streptogramin A acetyltransferase P50870 VATD_ENTFC Enterococcus faecium 3 0.7018
Streptogramin A acetyltransferase P50870 VATD_ENTFC Enterococcus faecium 3 0.7018
APH(2'')-Id O68183 O68183_ENTCA Enterococcus casseliflavus 4 0.7017
APH(2'')-Id O68183 O68183_ENTCA Enterococcus casseliflavus 4 0.7017
Aldehyde dehydrogenase, mitochondrial P05091 ALDH2_HUMAN Homo sapiens 4 0.7015
Aldehyde dehydrogenase, mitochondrial P05091 ALDH2_HUMAN Homo sapiens 4 0.7015
Beta-secretase 1 P56817 BACE1_HUMAN Homo sapiens 2 0.7014
Beta-secretase 1 P56817 BACE1_HUMAN Homo sapiens 2 0.7014
Mitogen-activated protein kinase 14 Q16539 MK14_HUMAN Homo sapiens 4 0.7012
Mitogen-activated protein kinase 14 Q16539 MK14_HUMAN Homo sapiens 4 0.7012
2',3'-cyclic-nucleotide 3'-phosphodiesterase P16330 CN37_MOUSE Mus musculus 2 0.7007
2',3'-cyclic-nucleotide 3'-phosphodiesterase P16330 CN37_MOUSE Mus musculus 2 0.7007
Nitric oxide synthase, inducible P29477 NOS2_MOUSE Mus musculus 3 0.7006
Glycoside Hydrolase Family 13 Q65MI2 Q65MI2_BACLD Bacillus licheniformis 2 0.7006
Nitric oxide synthase, inducible P29477 NOS2_MOUSE Mus musculus 3 0.7006
Glycoside Hydrolase Family 13 Q65MI2 Q65MI2_BACLD Bacillus licheniformis 2 0.7006
Retinol-binding protein 4 P18902 RET4_BOVIN Bos taurus 4 0.7005
Retinol-binding protein 4 P18902 RET4_BOVIN Bos taurus 4 0.7005
Tetracycline repressor protein class D P0ACT4 TETR4_ECOLX Escherichia coli 3 0.7002
Tetracycline repressor protein class D P0ACT4 TETR4_ECOLX Escherichia coli 3 0.7002
Chalcone--flavanone isomerase 1 P28012 CFI1_MEDSA Medicago sativa 3 0.7001
Chalcone--flavanone isomerase 1 P28012 CFI1_MEDSA Medicago sativa 3 0.7001

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