4-O-geranylcinnamyl acetate - Compound Card

4-O-geranylcinnamyl acetate

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4-O-geranylcinnamyl acetate

Structure
Zoomed Structure
  • Family: Leguminosae/Fabaceae
  • Kingdom: Plantae
  • Class: Cinnamyl Alcohol Derivative
Canonical Smiles C/C(=C\COc1ccc(cc1)/C=C/COC(=O)C)/CC=C(C)C
InChI InChI=1S/C20H26O3/c1-16(2)7-8-17(3)13-15-23-20-11-9-19(10-12-20)6-5-14-22-18(4)21/h5-7,9-13H,8,14-15H2,1-4H3/b6-5+,17-13+
InChIKey OTMMVLLHBWKTRV-WDGODYKHSA-N
Formula C20H26O3
HBA 3
HBD 0
MW 314.43
Rotatable Bonds 8
TPSA 35.53
LogP 4.94
Number Rings 1
Number Aromatic Rings 1
Heavy Atom Count 23
Formal Charge 0
Fraction CSP3 0.35
Exact Mass 314.19
Number of Lipinski Rule Violations 0
# Species Family Kingdom NCBI Taxonomy ID
1 Millettia usaramensis usaramensis Leguminosae/Fabaceae Plantae 53625

Showing of synonyms

  • Yenesew A, Midiwo JO, et al. (1998). Rotenoids, isoflavones and chalcones from the stem bark of Millettia usaramensis subspecies usaramensis. Phytochemistry,1998,47(2),295-300. [View] [PubMed]

No compound-protein relationship available.

Structure

SMILES: c1ccccc1

Level: 0

Mol. Weight: 78.11 g/mol

No bioactivities available.

Absorption

Caco-2 (logPapp)
-4.66
Human Oral Bioavailability 20%
Bioavailable
Human Intestinal Absorption
Absorbed
Madin-Darby Canine Kidney
-4.19
Human Oral Bioavailability 50%
Bioavailable
P-Glycoprotein Inhibitor
Inhibitor
P-Glycoprotein Substrate
Non-Substrate
Skin Permeability
-2.6

Distribution

Blood-Brain Barrier (CNS)
-
Blood-Brain Barrier
Penetrable
Fraction Unbound (Human)
0.79
Plasma Protein Binding
47.61
Steady State Volume of Distribution
-

Metabolism

Breast Cancer Resistance Protein
Non-Inhibitor
CYP 1A2 Inhibitor
Inhibitor
CYP 1A2 Substrate
Non-Substrate
CYP 2C19 Inhibitor
Non-Inhibitor
CYP 2C19 Substrate
Substrate
CYP 2C9 Inhibitor
Non-Inhibitor
CYP 2C9 Substrate
Substrate
CYP 2D6 Inhibitor
Non-Inhibitor
CYP 2D6 Substrate
Substrate
CYP 3A4 Inhibitor
Non-Inhibitor
CYP 3A4 Substrate
Non-Substrate
OATP1B1
Non-Inhibitor
OATP1B3
Non-Inhibitor

Excretion

Clearance
6.25
Organic Cation Transporter 2
Non-Inhibitor
Half-Life of Drug
-

Toxicity

AMES Mutagenesis
Safe
Avian
Safe
Bee
Toxic
Bioconcentration Factor
1.69
Biodegradation
Safe
Carcinogenesis
Toxic
Crustacean
Toxic
Liver Injury I (DILI)
Safe
Eye Corrosion
Safe
Eye Irritation
Safe
Maximum Tolerated Dose
1.16
Liver Injury II
Safe
hERG Blockers
Safe
Daphnia Maga
7.33
Micronucleos
Safe
NR-AhR
Safe
NR-AR
Safe
NR-AR-LBD
Safe
NR-Aromatase
Safe
NR-ER
Safe
NR-ER-LBD
Safe
NR-GR
Safe
NR-PPAR-gamma
Safe
NR-TR
Safe
T. Pyriformis
3.35
Rat (Acute)
1.94
Rat (Chronic Oral)
2.18
Fathead Minnow
5.52
Respiratory Disease
Toxic
Skin Sensitisation
Toxic
SR-ARE
Toxic
SR-ATAD5
Safe
SR-HSE
Safe
SR-MMP
Safe
SR-p53
Safe

General Properties

Boiling Point
354.43
Hydration Free Energy
-6.07
Log(D) at pH=7.4
4.44
Log(P)
5.74
Log S
-5.73
Log(Vapor Pressure)
-5.3
Melting Point
70.83
pKa Acid
12.44
pKa Basic
5.86
Protein Name UniProt ID Entry Name Species #Pharmacophore Points Probability (0.7 ≤ Tversky Score ≤ 1.0)
Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial Q33862 Q33862_ASCSU Ascaris suum 3 0.9424
Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial Q33862 Q33862_ASCSU Ascaris suum 3 0.9424
Vitamin D3 receptor P13053 VDR_RAT Rattus norvegicus 3 0.9284
Vitamin D3 receptor P13053 VDR_RAT Rattus norvegicus 3 0.9284
Heat shock protein HSP 90-alpha P07900 HS90A_HUMAN Homo sapiens 3 0.9160
Heat shock protein HSP 90-alpha P07900 HS90A_HUMAN Homo sapiens 3 0.9160
Corticosteroid-binding globulin P08185 CBG_HUMAN Homo sapiens 3 0.9128
Corticosteroid-binding globulin P08185 CBG_HUMAN Homo sapiens 3 0.9128
Sex hormone-binding globulin P04278 SHBG_HUMAN Homo sapiens 3 0.9068
Sex hormone-binding globulin P04278 SHBG_HUMAN Homo sapiens 3 0.9068
Pantothenate synthetase P9WIL5 PANC_MYCTU Mycobacterium tuberculosis 3 0.9056
Pantothenate synthetase P9WIL5 PANC_MYCTU Mycobacterium tuberculosis 3 0.9056
Rhodopsin P02699 OPSD_BOVIN Bos taurus 3 0.9035
Rhodopsin P02699 OPSD_BOVIN Bos taurus 3 0.9035
Hemolymph juvenile hormone binding protein Q9U556 Q9U556_BOMMO Bombyx mori 4 0.9009
Hemolymph juvenile hormone binding protein Q9U556 Q9U556_BOMMO Bombyx mori 4 0.9009
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A Q9Y233 PDE10_HUMAN Homo sapiens 3 0.9008
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A Q9Y233 PDE10_HUMAN Homo sapiens 3 0.9008
Retinoic acid receptor RXR-alpha P19793 RXRA_HUMAN Homo sapiens 3 0.8958
Retinoic acid receptor RXR-alpha P19793 RXRA_HUMAN Homo sapiens 3 0.8958
CmeR Q7B8P6 Q7B8P6_CAMJU Campylobacter jejuni 3 0.8884
CmeR Q7B8P6 Q7B8P6_CAMJU Campylobacter jejuni 3 0.8884
Methylketone synthase I E0YCS2 E0YCS2_SOLHA Solanum habrochaites 3 0.8849
Methylketone synthase I E0YCS2 E0YCS2_SOLHA Solanum habrochaites 3 0.8849
Beta-lactoglobulin P02754 LACB_BOVIN Bos taurus 3 0.8811
Beta-lactoglobulin P02754 LACB_BOVIN Bos taurus 3 0.8811
Mycinamicin III 3''-O-methyltransferase Q49492 MYCF_MICGR Micromonospora griseorubida 2 0.8804
Mycinamicin III 3''-O-methyltransferase Q49492 MYCF_MICGR Micromonospora griseorubida 2 0.8804
Glutamate receptor 2 P19491 GRIA2_RAT Rattus norvegicus 3 0.8732
Glutamate receptor 2 P19491 GRIA2_RAT Rattus norvegicus 3 0.8732
Mycinamicin III 3''-O-methyltransferase Q49492 MYCF_MICGR Micromonospora griseorubida 2 0.8688
Mycinamicin III 3''-O-methyltransferase Q49492 MYCF_MICGR Micromonospora griseorubida 2 0.8688
Retinol dehydratase Q26490 Q26490_SPOFR Spodoptera frugiperda 3 0.8588
Retinol dehydratase Q26490 Q26490_SPOFR Spodoptera frugiperda 3 0.8588
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 P04191 AT2A1_RABIT Oryctolagus cuniculus 3 0.8510
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 P04191 AT2A1_RABIT Oryctolagus cuniculus 3 0.8510
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 P04191 AT2A1_RABIT Oryctolagus cuniculus 3 0.8418
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 P04191 AT2A1_RABIT Oryctolagus cuniculus 3 0.8418
DNA gyrase subunit A P0AES5 GYRA_SHIFL Shigella flexneri 3 0.8323
DNA gyrase subunit A P0AES5 GYRA_SHIFL Shigella flexneri 3 0.8323
Glycogen synthase kinase-3 beta P49841 GSK3B_HUMAN Homo sapiens 3 0.8322
Glycogen synthase kinase-3 beta P49841 GSK3B_HUMAN Homo sapiens 3 0.8322
Progesterone receptor P06401 PRGR_HUMAN Homo sapiens 3 0.8167
Progesterone receptor P06401 PRGR_HUMAN Homo sapiens 3 0.8167
Progesterone receptor P06401 PRGR_HUMAN Homo sapiens 3 0.8138
Progesterone receptor P06401 PRGR_HUMAN Homo sapiens 3 0.8138
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial Q15119 PDK2_HUMAN Homo sapiens 3 0.8131
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial Q15119 PDK2_HUMAN Homo sapiens 3 0.8131
Beta-elicitin cryptogein P15570 ELIB_PHYCR Phytophthora cryptogea 3 0.8077
Beta-elicitin cryptogein P15570 ELIB_PHYCR Phytophthora cryptogea 3 0.8077
Ferrochelatase, mitochondrial P22830 HEMH_HUMAN Homo sapiens 2 0.8053
Ferrochelatase, mitochondrial P22830 HEMH_HUMAN Homo sapiens 2 0.8053
Aldo-keto reductase family 1 member C2 P52895 AK1C2_HUMAN Homo sapiens 2 0.8002
Aldo-keto reductase family 1 member C2 P52895 AK1C2_HUMAN Homo sapiens 2 0.8002
Lactoylglutathione lyase Q9CPU0 LGUL_MOUSE Mus musculus 2 0.7988
Lactoylglutathione lyase Q9CPU0 LGUL_MOUSE Mus musculus 2 0.7988
Beta-secretase 1 P56817 BACE1_HUMAN Homo sapiens 2 0.7974
Beta-secretase 1 P56817 BACE1_HUMAN Homo sapiens 2 0.7974
Aldo-keto reductase family 1 member C2 P52895 AK1C2_HUMAN Homo sapiens 2 0.7966
Aldo-keto reductase family 1 member C2 P52895 AK1C2_HUMAN Homo sapiens 2 0.7966
Peptidyl-prolyl cis-trans isomerase FKBP1A P62942 FKB1A_HUMAN Homo sapiens 2 0.7891
Peptidyl-prolyl cis-trans isomerase FKBP1A P62942 FKB1A_HUMAN Homo sapiens 2 0.7891
Beta-secretase 1 P56817 BACE1_HUMAN Homo sapiens 2 0.7890
Beta-secretase 1 P56817 BACE1_HUMAN Homo sapiens 2 0.7890
2-phospho-L-lactate transferase Q8PVT6 COFD_METMA Methanosarcina mazei 3 0.7870
2-phospho-L-lactate transferase Q8PVT6 COFD_METMA Methanosarcina mazei 3 0.7870
Retinol-binding protein 1 P02696 RET1_RAT Rattus norvegicus 3 0.7844
Retinol-binding protein 1 P02696 RET1_RAT Rattus norvegicus 3 0.7844
DNA double-strand break repair protein Mre11 Q9X1X0 Q9X1X0_THEMA Thermotoga maritima MSB8 3 0.7815
DNA double-strand break repair protein Mre11 Q9X1X0 Q9X1X0_THEMA Thermotoga maritima MSB8 3 0.7815
Lanosterol 14-alpha-demethylase Q385E8 Q385E8_TRYB2 Trypanosoma brucei brucei 3 0.7813
Lanosterol 14-alpha-demethylase Q385E8 Q385E8_TRYB2 Trypanosoma brucei brucei 3 0.7813
Aldo-keto reductase family 1 member C2 P52895 AK1C2_HUMAN Homo sapiens 3 0.7797
Aldo-keto reductase family 1 member C2 P52895 AK1C2_HUMAN Homo sapiens 3 0.7797
Retinoic acid receptor RXR Q8T5C6 RXR_BIOGL Biomphalaria glabrata 3 0.7793
Retinoic acid receptor RXR Q8T5C6 RXR_BIOGL Biomphalaria glabrata 3 0.7793
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform P48736 PK3CG_HUMAN Homo sapiens 3 0.7788
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform P48736 PK3CG_HUMAN Homo sapiens 3 0.7788
Sulfotransferase 2B1 O00204 ST2B1_HUMAN Homo sapiens 2 0.7778
Bacteriorhodopsin P02945 BACR_HALSA Halobacterium salinarum 3 0.7778
Bacteriorhodopsin P02945 BACR_HALSA Halobacterium salinarum 3 0.7778
Sulfotransferase 2B1 O00204 ST2B1_HUMAN Homo sapiens 2 0.7778
prolyl oligopeptidase Q9X6R4 Q9X6R4_AERCA Aeromonas caviae 2 0.7762
prolyl oligopeptidase Q9X6R4 Q9X6R4_AERCA Aeromonas caviae 2 0.7762
3',5'-cyclic-AMP phosphodiesterase 4D Q08499 PDE4D_HUMAN Homo sapiens 2 0.7755
3',5'-cyclic-AMP phosphodiesterase 4D Q08499 PDE4D_HUMAN Homo sapiens 2 0.7755
Vitamin D3 receptor P13053 VDR_RAT Rattus norvegicus 3 0.7752
Vitamin D3 receptor P13053 VDR_RAT Rattus norvegicus 3 0.7752
Aldo-keto reductase family 1 member D1 P51857 AK1D1_HUMAN Homo sapiens 2 0.7750
Aldo-keto reductase family 1 member D1 P51857 AK1D1_HUMAN Homo sapiens 2 0.7750
Aldo-keto reductase family 1 member D1 P51857 AK1D1_HUMAN Homo sapiens 3 0.7743
Aldo-keto reductase family 1 member D1 P51857 AK1D1_HUMAN Homo sapiens 3 0.7743
Aldo-keto reductase family 1 member D1 P51857 AK1D1_HUMAN Homo sapiens 2 0.7740
Aldo-keto reductase family 1 member D1 P51857 AK1D1_HUMAN Homo sapiens 2 0.7740
Putative cytochrome P450 120 Q59990 CP120_SYNY3 Synechocystis sp 3 0.7736
Putative cytochrome P450 120 Q59990 CP120_SYNY3 Synechocystis sp 3 0.7736
Probable NDP-rhamnosyltransferase Q9ALM8 Q9ALM8_SACSN Saccharopolyspora spinosa 2 0.7732
Probable NDP-rhamnosyltransferase Q9ALM8 Q9ALM8_SACSN Saccharopolyspora spinosa 2 0.7732
Aldo-keto reductase family 1 member D1 P51857 AK1D1_HUMAN Homo sapiens 2 0.7730
Aldo-keto reductase family 1 member D1 P51857 AK1D1_HUMAN Homo sapiens 2 0.7730
Retinol-binding protein 4 P18902 RET4_BOVIN Bos taurus 3 0.7728
Retinol-binding protein 4 P18902 RET4_BOVIN Bos taurus 3 0.7728
Vitamin D3 receptor P13053 VDR_RAT Rattus norvegicus 3 0.7727
Vitamin D3 receptor P13053 VDR_RAT Rattus norvegicus 3 0.7727
Vitamin D3 receptor P13053 VDR_RAT Rattus norvegicus 3 0.7726
Vitamin D3 receptor P13053 VDR_RAT Rattus norvegicus 3 0.7726
Tetracycline repressor protein class D P0ACT4 TETR4_ECOLX Escherichia coli 2 0.7721
Tetracycline repressor protein class D P0ACT4 TETR4_ECOLX Escherichia coli 2 0.7721
Jasmonoyl--L-amino acid synthetase JAR1 Q9SKE2 JAR1_ARATH Arabidopsis thaliana 3 0.7706
Jasmonoyl--L-amino acid synthetase JAR1 Q9SKE2 JAR1_ARATH Arabidopsis thaliana 3 0.7706
Aldo-keto reductase family 1 member C2 P52895 AK1C2_HUMAN Homo sapiens 2 0.7690
Aldo-keto reductase family 1 member C2 P52895 AK1C2_HUMAN Homo sapiens 2 0.7690
Methylketone synthase I E0YCS2 E0YCS2_SOLHA Solanum habrochaites 2 0.7689
Methylketone synthase I E0YCS2 E0YCS2_SOLHA Solanum habrochaites 2 0.7689
3-ketosteroid dehydrogenase Q9RA02 Q9RA02_RHOER Rhodococcus erythropolis 2 0.7657
3-ketosteroid dehydrogenase Q9RA02 Q9RA02_RHOER Rhodococcus erythropolis 2 0.7657
Ferrochelatase, mitochondrial P22830 HEMH_HUMAN Homo sapiens 3 0.7655
Ferrochelatase, mitochondrial P22830 HEMH_HUMAN Homo sapiens 3 0.7655
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 P04191 AT2A1_RABIT Oryctolagus cuniculus 2 0.7650
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 P04191 AT2A1_RABIT Oryctolagus cuniculus 2 0.7650
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 P04191 AT2A1_RABIT Oryctolagus cuniculus 2 0.7637
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 P04191 AT2A1_RABIT Oryctolagus cuniculus 2 0.7637
Sex hormone-binding globulin P04278 SHBG_HUMAN Homo sapiens 3 0.7633
Sex hormone-binding globulin P04278 SHBG_HUMAN Homo sapiens 3 0.7633
Nuclear receptor ROR-gamma P51449 RORG_HUMAN Homo sapiens 2 0.7619
Nuclear receptor ROR-gamma P51449 RORG_HUMAN Homo sapiens 2 0.7619
Steroid Delta-isomerase P07445 SDIS_PSEPU Pseudomonas putida 2 0.7613
Steroid Delta-isomerase P07445 SDIS_PSEPU Pseudomonas putida 2 0.7613
Ferrochelatase, mitochondrial P22830 HEMH_HUMAN Homo sapiens 2 0.7610
Ferrochelatase, mitochondrial P22830 HEMH_HUMAN Homo sapiens 2 0.7610
Thymidylate synthase Q4JQW2 TYSY_VZVO Varicella-zoster virus 3 0.7608
Thymidylate synthase Q4JQW2 TYSY_VZVO Varicella-zoster virus 3 0.7608
Class B acid phosphatase Q540U1 APHA_SALTM Salmonella typhimurium 2 0.7608
Class B acid phosphatase Q540U1 APHA_SALTM Salmonella typhimurium 2 0.7608
Abscisic acid receptor PYL3 Q9SSM7 PYL3_ARATH Arabidopsis thaliana 2 0.7596
Abscisic acid receptor PYL3 Q9SSM7 PYL3_ARATH Arabidopsis thaliana 2 0.7596
Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 Q9Y3Z3 SAMH1_HUMAN Homo sapiens 3 0.7586
Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 Q9Y3Z3 SAMH1_HUMAN Homo sapiens 3 0.7586
Aldo-keto reductase family 1 member D1 P51857 AK1D1_HUMAN Homo sapiens 3 0.7568
Aldo-keto reductase family 1 member D1 P51857 AK1D1_HUMAN Homo sapiens 3 0.7568
Nuclear receptor ROR-gamma P51449 RORG_HUMAN Homo sapiens 3 0.7566
Nuclear receptor ROR-gamma P51449 RORG_HUMAN Homo sapiens 3 0.7566
Retinoic acid receptor RXR-alpha P19793 RXRA_HUMAN Homo sapiens 3 0.7566
Cartilage oligomeric matrix protein P35444 COMP_RAT Rattus norvegicus 3 0.7566
Cartilage oligomeric matrix protein P35444 COMP_RAT Rattus norvegicus 3 0.7566
Retinoic acid receptor RXR-alpha P19793 RXRA_HUMAN Homo sapiens 3 0.7566
ATP-dependent molecular chaperone HSP82 P02829 HSP82_YEAST Saccharomyces cerevisiae 3 0.7565
ATP-dependent molecular chaperone HSP82 P02829 HSP82_YEAST Saccharomyces cerevisiae 3 0.7565
CCA-adding enzyme O28126 CCA_ARCFU Archaeoglobus fulgidus 2 0.7562
Acetylcholinesterase P04058 ACES_TETCF Tetronarce californica 3 0.7562
CCA-adding enzyme O28126 CCA_ARCFU Archaeoglobus fulgidus 2 0.7562
Acetylcholinesterase P04058 ACES_TETCF Tetronarce californica 3 0.7562
3'-5' exoribonuclease Rv2179c P9WJ73 EXRBN_MYCTU Mycobacterium tuberculosis 2 0.7561
3'-5' exoribonuclease Rv2179c P9WJ73 EXRBN_MYCTU Mycobacterium tuberculosis 2 0.7561
3',5'-cyclic-AMP phosphodiesterase 4D Q08499 PDE4D_HUMAN Homo sapiens 2 0.7547
3',5'-cyclic-AMP phosphodiesterase 4D Q08499 PDE4D_HUMAN Homo sapiens 2 0.7547
Steroid Delta-isomerase P00947 SDIS_COMTE Comamonas testosteroni 2 0.7540
Steroid Delta-isomerase P00947 SDIS_COMTE Comamonas testosteroni 2 0.7540
Androgen receptor P10275 ANDR_HUMAN Homo sapiens 2 0.7516
Androgen receptor P10275 ANDR_HUMAN Homo sapiens 2 0.7516
Steroid Delta-isomerase P00947 SDIS_COMTE Comamonas testosteroni 2 0.7507
Steroid Delta-isomerase P00947 SDIS_COMTE Comamonas testosteroni 2 0.7507
Sulfotransferase 2A1 Q06520 ST2A1_HUMAN Homo sapiens 2 0.7501
Sulfotransferase 2A1 Q06520 ST2A1_HUMAN Homo sapiens 2 0.7501
NADPH-dependent oxidoreductase 2-alkenal reductase Q39172 AER_ARATH Arabidopsis thaliana 2 0.7496
NADPH-dependent oxidoreductase 2-alkenal reductase Q39172 AER_ARATH Arabidopsis thaliana 2 0.7496
Cyclic nucleotide-gated potassium channel mll3241 Q98GN8 CNGK1_RHILO Mesorhizobium japonicum) 2 0.7491
Cyclic nucleotide-gated potassium channel mll3241 Q98GN8 CNGK1_RHILO Mesorhizobium japonicum) 2 0.7491
2',3'-cyclic-nucleotide 3'-phosphodiesterase P16330 CN37_MOUSE Mus musculus 2 0.7486
2',3'-cyclic-nucleotide 3'-phosphodiesterase P16330 CN37_MOUSE Mus musculus 2 0.7486
NPC intracellular cholesterol transporter 1 O15118 NPC1_HUMAN Homo sapiens 3 0.7485
NPC intracellular cholesterol transporter 1 O15118 NPC1_HUMAN Homo sapiens 3 0.7485
cGMP-dependent protein kinase 1 Q13976 KGP1_HUMAN Homo sapiens 2 0.7482
cGMP-dependent protein kinase 1 Q13976 KGP1_HUMAN Homo sapiens 2 0.7482
Aldo-keto reductase family 1 member C1 Q04828 AK1C1_HUMAN Homo sapiens 2 0.7481
Aldo-keto reductase family 1 member C1 Q04828 AK1C1_HUMAN Homo sapiens 2 0.7481
17-beta-hydroxysteroid dehydrogenase type 1 P14061 DHB1_HUMAN Homo sapiens 2 0.7466
17-beta-hydroxysteroid dehydrogenase type 1 P14061 DHB1_HUMAN Homo sapiens 2 0.7466
cGMP-dependent protein kinase 1 Q13976 KGP1_HUMAN Homo sapiens 2 0.7451
cGMP-dependent protein kinase 1 Q13976 KGP1_HUMAN Homo sapiens 2 0.7451
Carbonic anhydrase 2 P00918 CAH2_HUMAN Homo sapiens 2 0.7451
Carbonic anhydrase 2 P00918 CAH2_HUMAN Homo sapiens 2 0.7451
Glucan 1,3-beta-glucosidase P29717 EXG1_CANAL Candida albicans 2 0.7448
Glucan 1,3-beta-glucosidase P29717 EXG1_CANAL Candida albicans 2 0.7448
Tyrosine-protein kinase JAK2 O60674 JAK2_HUMAN Homo sapiens 2 0.7447
Tyrosine-protein kinase JAK2 O60674 JAK2_HUMAN Homo sapiens 2 0.7447
3-alpha-hydroxysteroid dehydrogenase P23457 DIDH_RAT Rattus norvegicus 2 0.7442
3-alpha-hydroxysteroid dehydrogenase P23457 DIDH_RAT Rattus norvegicus 2 0.7442
cGMP-dependent protein kinase 1 Q13976 KGP1_HUMAN Homo sapiens 2 0.7440
cGMP-dependent protein kinase 1 Q13976 KGP1_HUMAN Homo sapiens 2 0.7440
Mitogen-activated protein kinase 8 P45983 MK08_HUMAN Homo sapiens 2 0.7439
Mitogen-activated protein kinase 8 P45983 MK08_HUMAN Homo sapiens 2 0.7439
Glucan 1,3-beta-glucosidase P29717 EXG1_CANAL Candida albicans 2 0.7435
Glucan 1,3-beta-glucosidase P29717 EXG1_CANAL Candida albicans 2 0.7435
Mitogen-activated protein kinase 8 P45983 MK08_HUMAN Homo sapiens 2 0.7435
Mitogen-activated protein kinase 8 P45983 MK08_HUMAN Homo sapiens 2 0.7435
CmeR Q7B8P6 Q7B8P6_CAMJU Campylobacter jejuni 2 0.7430
CmeR Q7B8P6 Q7B8P6_CAMJU Campylobacter jejuni 2 0.7430
cAMP-dependent protein kinase type I-alpha regulatory subunit P00514 KAP0_BOVIN Bos taurus 2 0.7425
cAMP-dependent protein kinase type I-alpha regulatory subunit P00514 KAP0_BOVIN Bos taurus 2 0.7425
Aldo-keto reductase family 1 member D1 P51857 AK1D1_HUMAN Homo sapiens 2 0.7421
Aldo-keto reductase family 1 member D1 P51857 AK1D1_HUMAN Homo sapiens 2 0.7421
Cyclic AMP receptor protein Q5SID7 CRP_THET8 Thermus thermophilus 2 0.7419
Cyclic AMP receptor protein Q5SID7 CRP_THET8 Thermus thermophilus 2 0.7419
Sulfide-quinone reductase B7JBP8 SQRD_ACIF2 Acidithiobacillus ferrooxidans) 2 0.7415
Sulfide-quinone reductase B7JBP8 SQRD_ACIF2 Acidithiobacillus ferrooxidans) 2 0.7415
Flavin-dependent monooxygenase Q93L51 TETX_BACT4 Bacteroides thetaiotaomicron 2 0.7409
Flavin-dependent monooxygenase Q93L51 TETX_BACT4 Bacteroides thetaiotaomicron 2 0.7409
Macrophage metalloelastase P39900 MMP12_HUMAN Homo sapiens 2 0.7403
Macrophage metalloelastase P39900 MMP12_HUMAN Homo sapiens 2 0.7403
Non-receptor tyrosine-protein kinase TYK2 P29597 TYK2_HUMAN Homo sapiens 2 0.7396
Non-receptor tyrosine-protein kinase TYK2 P29597 TYK2_HUMAN Homo sapiens 2 0.7396
Beta-lactoglobulin P02754 LACB_BOVIN Bos taurus 2 0.7391
Beta-lactoglobulin P02754 LACB_BOVIN Bos taurus 2 0.7391
Nuclear receptor ROR-beta P45446 RORB_RAT Rattus norvegicus 2 0.7388
Nuclear receptor ROR-beta P45446 RORB_RAT Rattus norvegicus 2 0.7388
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 O88703 HCN2_MOUSE Mus musculus 2 0.7379
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 O88703 HCN2_MOUSE Mus musculus 2 0.7379
Fatty acid-binding protein, liver P80226 FABPL_CHICK Gallus gallus 2 0.7378
Fatty acid-binding protein, liver P80226 FABPL_CHICK Gallus gallus 2 0.7378
2',3'-cyclic-nucleotide 3'-phosphodiesterase P16330 CN37_MOUSE Mus musculus 2 0.7373
2',3'-cyclic-nucleotide 3'-phosphodiesterase P16330 CN37_MOUSE Mus musculus 2 0.7373
Retinol-binding protein 2 P50120 RET2_HUMAN Homo sapiens 3 0.7369
Retinol-binding protein 2 P50120 RET2_HUMAN Homo sapiens 3 0.7369
Adenylate cyclase 2 A0A2U2H3Y1 A0A384LKY8_YERPE Yersinia pestis 2 0.7368
Adenylate cyclase 2 A0A2U2H3Y1 A0A384LKY8_YERPE Yersinia pestis 2 0.7368
Acetylcholinesterase P21836 ACES_MOUSE Mus musculus 3 0.7366
Acetylcholinesterase P21836 ACES_MOUSE Mus musculus 3 0.7366
cAMP-dependent protein kinase type I-alpha regulatory subunit P00514 KAP0_BOVIN Bos taurus 2 0.7365
cAMP-dependent protein kinase type I-alpha regulatory subunit P00514 KAP0_BOVIN Bos taurus 2 0.7365
Retinoic acid receptor RXR-alpha P19793 RXRA_HUMAN Homo sapiens 3 0.7363
Retinoic acid receptor RXR-alpha P19793 RXRA_HUMAN Homo sapiens 3 0.7363
Retinoic acid receptor beta P10826 RARB_HUMAN Homo sapiens 3 0.7362
Retinoic acid receptor beta P10826 RARB_HUMAN Homo sapiens 3 0.7362
Type IV / VI secretion system DotU domain-containing protein Q9KN50 Q9KN50_VIBCH Vibrio cholerae serotype O1 2 0.7361
Type IV / VI secretion system DotU domain-containing protein Q9KN50 Q9KN50_VIBCH Vibrio cholerae serotype O1 2 0.7361
Pentaerythritol tetranitrate reductase P71278 P71278_ENTCL Enterobacter cloacae 2 0.7360
Pentaerythritol tetranitrate reductase P71278 P71278_ENTCL Enterobacter cloacae 2 0.7360
Retinol-binding protein 1 P09455 RET1_HUMAN Homo sapiens 3 0.7350
Retinol-binding protein 1 P09455 RET1_HUMAN Homo sapiens 3 0.7350
Nucleoside 2-deoxyribosyltransferase Q8RLY5 Q8RLY5_LACHE Lactobacillus helveticus 2 0.7349
Nucleoside 2-deoxyribosyltransferase Q8RLY5 Q8RLY5_LACHE Lactobacillus helveticus 2 0.7349
Serine/threonine-protein kinase 24 Q9Y6E0 STK24_HUMAN Homo sapiens 2 0.7347
Serine/threonine-protein kinase 24 Q9Y6E0 STK24_HUMAN Homo sapiens 2 0.7347
Nucleoside diphosphate kinase Q5UQL3 NDK_MIMIV Acanthamoeba polyphaga mimivirus 2 0.7345
Nucleoside diphosphate kinase Q5UQL3 NDK_MIMIV Acanthamoeba polyphaga mimivirus 2 0.7345
Heat shock protein HSP 90-alpha P07900 HS90A_HUMAN Homo sapiens 2 0.7343
Heat shock protein HSP 90-alpha P07900 HS90A_HUMAN Homo sapiens 2 0.7343
Basic phospholipase A2 VRV-PL-VIIIa P59071 PA2B8_DABRR Daboia russelii 2 0.7342
Basic phospholipase A2 VRV-PL-VIIIa P59071 PA2B8_DABRR Daboia russelii 2 0.7342
Methionine aminopeptidase 2 P50579 MAP2_HUMAN Homo sapiens 2 0.7337
Methionine aminopeptidase 2 P50579 MAP2_HUMAN Homo sapiens 2 0.7337
Mitochondrial poly(A) polymerase F1NBW0 F1NBW0_CHICK Gallus gallus 2 0.7335
Mitochondrial poly(A) polymerase F1NBW0 F1NBW0_CHICK Gallus gallus 2 0.7335
Pantothenate synthetase P9WIL4 PANC_MYCTO Mycobacterium tuberculosis 2 0.7333
Pantothenate synthetase P9WIL4 PANC_MYCTO Mycobacterium tuberculosis 2 0.7333
Mitogen-activated protein kinase 8 P45983 MK08_HUMAN Homo sapiens 2 0.7328
Mitogen-activated protein kinase 8 P45983 MK08_HUMAN Homo sapiens 2 0.7328
Retinoic acid receptor gamma P13631 RARG_HUMAN Homo sapiens 3 0.7324
Retinoic acid receptor gamma P13631 RARG_HUMAN Homo sapiens 3 0.7324
Retinoic acid receptor RXR-alpha P19793 RXRA_HUMAN Homo sapiens 3 0.7322
Retinoic acid receptor RXR-alpha P19793 RXRA_HUMAN Homo sapiens 3 0.7322
Sulfotransferase 2B1 O00204 ST2B1_HUMAN Homo sapiens 2 0.7320
Sulfotransferase 2B1 O00204 ST2B1_HUMAN Homo sapiens 2 0.7320
Reaction center protein L chain P0C0Y7 RCEH_RHOSH Rhodobacter sphaeroides 2 0.7319
Reaction center protein L chain P0C0Y7 RCEH_RHOSH Rhodobacter sphaeroides 2 0.7319
Rhodopsin P02699 OPSD_BOVIN Bos taurus 2 0.7319
Rhodopsin P02699 OPSD_BOVIN Bos taurus 2 0.7319
5-methylthioadenosine/S-adenosylhomocysteine deaminase Q7NZ90 Q7NZ90_CHRVO Chromobacterium violaceum 2 0.7318
5-methylthioadenosine/S-adenosylhomocysteine deaminase Q7NZ90 Q7NZ90_CHRVO Chromobacterium violaceum 2 0.7318
N-terminal acetyltransferase A complex subunit NAT1 P12945 NAT1_YEAST Saccharomyces cerevisiae 2 0.7314
N-terminal acetyltransferase A complex subunit NAT1 P12945 NAT1_YEAST Saccharomyces cerevisiae 2 0.7314
Metallophosphoesterase A3DJ38 A3DJ38_HUNT2 Clostridium thermocellum 2 0.7310
Metallophosphoesterase A3DJ38 A3DJ38_HUNT2 Clostridium thermocellum 2 0.7310
17-beta-hydroxysteroid dehydrogenase type 1 P14061 DHB1_HUMAN Homo sapiens 2 0.7308
17-beta-hydroxysteroid dehydrogenase type 1 P14061 DHB1_HUMAN Homo sapiens 2 0.7308
Aminopeptidase N P15145 AMPN_PIG Sus scrofa 2 0.7304
Aminopeptidase N P15145 AMPN_PIG Sus scrofa 2 0.7304
Queuine tRNA-ribosyltransferase P28720 TGT_ZYMMO Zymomonas mobilis subsp. mobilis 2 0.7303
Queuine tRNA-ribosyltransferase P28720 TGT_ZYMMO Zymomonas mobilis subsp. mobilis 2 0.7303
Purine nucleoside phosphorylase DeoD-type P0ABP9 DEOD_ECO57 Escherichia coli O157:H7 2 0.7301
Purine nucleoside phosphorylase DeoD-type P0ABP9 DEOD_ECO57 Escherichia coli O157:H7 2 0.7301
4,4'-diapophytoene synthase A9JQL9 CRTM_STAAU Staphylococcus aureus 2 0.7297
BMP-2-inducible protein kinase Q9NSY1 BMP2K_HUMAN Homo sapiens 2 0.7297
4,4'-diapophytoene synthase A9JQL9 CRTM_STAAU Staphylococcus aureus 2 0.7297
BMP-2-inducible protein kinase Q9NSY1 BMP2K_HUMAN Homo sapiens 2 0.7297
2',3'-cyclic-nucleotide 3'-phosphodiesterase P16330 CN37_MOUSE Mus musculus 2 0.7290
2',3'-cyclic-nucleotide 3'-phosphodiesterase P16330 CN37_MOUSE Mus musculus 2 0.7290
Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 Q9Y3Z3 SAMH1_HUMAN Homo sapiens 2 0.7289
Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 Q9Y3Z3 SAMH1_HUMAN Homo sapiens 2 0.7289
Retinoic acid receptor RXR-alpha P28700 RXRA_MOUSE Mus musculus 3 0.7280
Retinoic acid receptor RXR-alpha P28700 RXRA_MOUSE Mus musculus 3 0.7280
Non-receptor tyrosine-protein kinase TYK2 P29597 TYK2_HUMAN Homo sapiens 2 0.7277
Non-receptor tyrosine-protein kinase TYK2 P29597 TYK2_HUMAN Homo sapiens 2 0.7277
11-beta-hydroxysteroid dehydrogenase 1 P28845 DHI1_HUMAN Homo sapiens 2 0.7271
11-beta-hydroxysteroid dehydrogenase 1 P28845 DHI1_HUMAN Homo sapiens 2 0.7271
Non-receptor tyrosine-protein kinase TYK2 P29597 TYK2_HUMAN Homo sapiens 2 0.7270
Non-receptor tyrosine-protein kinase TYK2 P29597 TYK2_HUMAN Homo sapiens 2 0.7270
2',3'-cyclic-nucleotide 3'-phosphodiesterase P16330 CN37_MOUSE Mus musculus 2 0.7261
2',3'-cyclic-nucleotide 3'-phosphodiesterase P16330 CN37_MOUSE Mus musculus 2 0.7261
Histone deacetylase-like amidohydrolase Q70I53 HDAH_ALCSD Alcaligenes sp.) 2 0.7258
Histone deacetylase-like amidohydrolase Q70I53 HDAH_ALCSD Alcaligenes sp.) 2 0.7258
Enoyl-[acyl-carrier-protein] reductase [NADH] P9WGR1 INHA_MYCTU Mycobacterium tuberculosis 2 0.7258
Enoyl-[acyl-carrier-protein] reductase [NADH] P9WGR1 INHA_MYCTU Mycobacterium tuberculosis 2 0.7258
HTH-type transcriptional repressor PurR P0ACP7 PURR_ECOLI Escherichia coli 2 0.7254
HTH-type transcriptional repressor PurR P0ACP7 PURR_ECOLI Escherichia coli 2 0.7254
Acetylcholinesterase P21836 ACES_MOUSE Mus musculus 2 0.7253
Acetylcholinesterase P21836 ACES_MOUSE Mus musculus 2 0.7253
Prostaglandin reductase 2 Q8N8N7 PTGR2_HUMAN Homo sapiens 2 0.7252
Prostaglandin reductase 2 Q8N8N7 PTGR2_HUMAN Homo sapiens 2 0.7252
2',3'-cyclic-nucleotide 3'-phosphodiesterase P16330 CN37_MOUSE Mus musculus 2 0.7246
2',3'-cyclic-nucleotide 3'-phosphodiesterase P16330 CN37_MOUSE Mus musculus 2 0.7246
Aldo-keto reductase family 1 member C3 P42330 AK1C3_HUMAN Homo sapiens 2 0.7245
Aldo-keto reductase family 1 member C3 P42330 AK1C3_HUMAN Homo sapiens 2 0.7245
Aldo-keto reductase family 1 member C3 P42330 AK1C3_HUMAN Homo sapiens 2 0.7245
2',3'-cyclic-nucleotide 3'-phosphodiesterase P16330 CN37_MOUSE Mus musculus 2 0.7245
Aldo-keto reductase family 1 member C3 P42330 AK1C3_HUMAN Homo sapiens 2 0.7245
2',3'-cyclic-nucleotide 3'-phosphodiesterase P16330 CN37_MOUSE Mus musculus 2 0.7245
Retinol-binding protein 4 P18902 RET4_BOVIN Bos taurus 3 0.7244
Retinol-binding protein 4 P18902 RET4_BOVIN Bos taurus 3 0.7244
Beta-1 adrenergic receptor P07700 ADRB1_MELGA Meleagris gallopavo 2 0.7243
Beta-1 adrenergic receptor P07700 ADRB1_MELGA Meleagris gallopavo 2 0.7243
Purine nucleoside phosphorylase DeoD-type Q5EEL8 DEOD_BACCE Bacillus cereus 2 0.7239
Purine nucleoside phosphorylase DeoD-type Q5EEL8 DEOD_BACCE Bacillus cereus 2 0.7239
cAMP-dependent protein kinase type II-beta regulatory subunit P12369 KAP3_RAT Rattus norvegicus 2 0.7239
cAMP-dependent protein kinase type II-beta regulatory subunit P12369 KAP3_RAT Rattus norvegicus 2 0.7239
Sex hormone-binding globulin P04278 SHBG_HUMAN Homo sapiens 3 0.7238
Sex hormone-binding globulin P04278 SHBG_HUMAN Homo sapiens 3 0.7238
Serine/threonine-protein kinase PLK1 P53350 PLK1_HUMAN Homo sapiens 3 0.7234
Serine/threonine-protein kinase PLK1 P53350 PLK1_HUMAN Homo sapiens 3 0.7234
Nuclear receptor subfamily 1 group I member 2 O75469 NR1I2_HUMAN Homo sapiens 3 0.7233
Nuclear receptor subfamily 1 group I member 2 O75469 NR1I2_HUMAN Homo sapiens 3 0.7233
Purine nucleoside phosphorylase P00491 PNPH_HUMAN Homo sapiens 2 0.7228
Purine nucleoside phosphorylase P00491 PNPH_HUMAN Homo sapiens 2 0.7228
Single-stranded-DNA-specific exonuclease RecJ D0EM60 D0EM60_DEIRD Deinococcus radiodurans 2 0.7226
Single-stranded-DNA-specific exonuclease RecJ D0EM60 D0EM60_DEIRD Deinococcus radiodurans 2 0.7226
Phenazine biosynthesis protein A/B Q396C9 Q396C9_BURL3 Burkholderia lata 2 0.7225
Phenazine biosynthesis protein A/B Q396C9 Q396C9_BURL3 Burkholderia lata 2 0.7225
Polymerase acidic protein C3W5S0 C3W5S0_I09A0 Influenza A virus 2 0.7223
2',3'-cyclic-nucleotide 3'-phosphodiesterase P16330 CN37_MOUSE Mus musculus 2 0.7223
Polymerase acidic protein C3W5S0 C3W5S0_I09A0 Influenza A virus 2 0.7223
2',3'-cyclic-nucleotide 3'-phosphodiesterase P16330 CN37_MOUSE Mus musculus 2 0.7223
Tetracycline repressor protein class D P0ACT4 TETR4_ECOLX Escherichia coli 3 0.7219
Cyclic nucleotide-binding domain-containing protein E0RR11 E0RR11_SPITD Spirochaeta thermophila 2 0.7219
Cyclic nucleotide-binding domain-containing protein E0RR11 E0RR11_SPITD Spirochaeta thermophila 2 0.7219
Tetracycline repressor protein class D P0ACT4 TETR4_ECOLX Escherichia coli 3 0.7219
Beta-galactoside-specific lectin 4 Q6ITZ3 ML4_VISAL Viscum album 2 0.7218
Beta-galactoside-specific lectin 4 Q6ITZ3 ML4_VISAL Viscum album 2 0.7218
Fibroblast growth factor receptor 1 P11362 FGFR1_HUMAN Homo sapiens 2 0.7213
Fibroblast growth factor receptor 1 P11362 FGFR1_HUMAN Homo sapiens 2 0.7213
Aldo-keto reductase family 1 member D1 P51857 AK1D1_HUMAN Homo sapiens 2 0.7209
Aldo-keto reductase family 1 member D1 P51857 AK1D1_HUMAN Homo sapiens 2 0.7209
ADP-ribosylation factor 1 P84077 ARF1_HUMAN Homo sapiens 2 0.7207
ADP-ribosylation factor 1 P84077 ARF1_HUMAN Homo sapiens 2 0.7207
Pentaerythritol tetranitrate reductase P71278 P71278_ENTCL Enterobacter cloacae 2 0.7204
Pentaerythritol tetranitrate reductase P71278 P71278_ENTCL Enterobacter cloacae 2 0.7204
Fatty acid-binding protein, liver P80226 FABPL_CHICK Gallus gallus 2 0.7199
Fatty acid-binding protein, liver P80226 FABPL_CHICK Gallus gallus 2 0.7199
Integrin alpha-L P20701 ITAL_HUMAN Homo sapiens 2 0.7196
Integrin alpha-L P20701 ITAL_HUMAN Homo sapiens 2 0.7196
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 Q9Y3Q4 HCN4_HUMAN Homo sapiens 2 0.7195
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 Q9Y3Q4 HCN4_HUMAN Homo sapiens 2 0.7195
Endothiapepsin P11838 CARP_CRYPA Cryphonectria parasitica 2 0.7185
Photosynthetic reaction center cytochrome c subunit P07173 CYCR_BLAVI Blastochloris viridis 2 0.7185
Photosynthetic reaction center cytochrome c subunit P07173 CYCR_BLAVI Blastochloris viridis 2 0.7185
Endothiapepsin P11838 CARP_CRYPA Cryphonectria parasitica 2 0.7185
Purine nucleoside phosphorylase DeoD-type P0ABP8 DEOD_ECOLI Escherichia coli 2 0.7181
Purine nucleoside phosphorylase DeoD-type P0ABP8 DEOD_ECOLI Escherichia coli 2 0.7181
Uncharacterized protein YML079W Q03629 YMH9_YEAST Saccharomyces cerevisiae 2 0.7177
Uncharacterized protein YML079W Q03629 YMH9_YEAST Saccharomyces cerevisiae 2 0.7177
Steroid C26-monooxygenase P9WPP1 CP125_MYCTU Mycobacterium tuberculosis 2 0.7174
Steroid C26-monooxygenase P9WPP1 CP125_MYCTU Mycobacterium tuberculosis 2 0.7174
LL-diaminopimelate aminotransferase, chloroplastic Q93ZN9 DAPAT_ARATH Arabidopsis thaliana 2 0.7172
LL-diaminopimelate aminotransferase, chloroplastic Q93ZN9 DAPAT_ARATH Arabidopsis thaliana 2 0.7172
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 O88703 HCN2_MOUSE Mus musculus 2 0.7166
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 O88703 HCN2_MOUSE Mus musculus 2 0.7166
Soluble cytochrome b562 P0ABE7 C562_ECOLX Escherichia coli 2 0.7156
Soluble cytochrome b562 P0ABE7 C562_ECOLX Escherichia coli 2 0.7156
HTH-type transcriptional regulator EthR P9WMC1 ETHR_MYCTU Mycobacterium tuberculosis 3 0.7152
HTH-type transcriptional regulator EthR P9WMC1 ETHR_MYCTU Mycobacterium tuberculosis 3 0.7152
HTH-type transcriptional repressor PurR P0ACP7 PURR_ECOLI Escherichia coli 2 0.7150
HTH-type transcriptional repressor PurR P0ACP7 PURR_ECOLI Escherichia coli 2 0.7150
Steroid Delta-isomerase P00947 SDIS_COMTE Comamonas testosteroni 2 0.7150
Steroid Delta-isomerase P00947 SDIS_COMTE Comamonas testosteroni 2 0.7150
Retinaldehyde-binding protein 1 P12271 RLBP1_HUMAN Homo sapiens 3 0.7148
Retinaldehyde-binding protein 1 P12271 RLBP1_HUMAN Homo sapiens 3 0.7148
Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 Q9Y3Z3 SAMH1_HUMAN Homo sapiens 2 0.7147
Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 Q9Y3Z3 SAMH1_HUMAN Homo sapiens 2 0.7147
Steroid 17-alpha-hydroxylase/17,20 lyase P05093 CP17A_HUMAN Homo sapiens 3 0.7144
Steroid 17-alpha-hydroxylase/17,20 lyase P05093 CP17A_HUMAN Homo sapiens 3 0.7144
DNA-directed DNA polymerase Q38087 DPOL_BPR69 Escherichia phage RB69 2 0.7141
DNA-directed DNA polymerase Q38087 DPOL_BPR69 Escherichia phage RB69 2 0.7141
Thymidylate synthase P0A884 TYSY_ECOLI Escherichia coli 2 0.7138
Thymidylate synthase P0A884 TYSY_ECOLI Escherichia coli 2 0.7138
cAMP-dependent protein kinase type II-beta regulatory subunit P12369 KAP3_RAT Rattus norvegicus 2 0.7135
cAMP-dependent protein kinase type II-beta regulatory subunit P12369 KAP3_RAT Rattus norvegicus 2 0.7135
cGMP-dependent protein kinase 2 Q13237 KGP2_HUMAN Homo sapiens 2 0.7135
cGMP-dependent protein kinase 2 Q13237 KGP2_HUMAN Homo sapiens 2 0.7135
4,4'-diapophytoene synthase A9JQL9 CRTM_STAAU Staphylococcus aureus 3 0.7134
4,4'-diapophytoene synthase A9JQL9 CRTM_STAAU Staphylococcus aureus 3 0.7134
Nucleoside diphosphate kinase A5J299 A5J299_PENVA Penaeus vannamei 2 0.7123
Nucleoside diphosphate kinase A5J299 A5J299_PENVA Penaeus vannamei 2 0.7123
Fatty acid-binding protein 10-A, liver basic Q9I8L5 FA10A_DANRE Danio rerio 2 0.7121
Fatty acid-binding protein 10-A, liver basic Q9I8L5 FA10A_DANRE Danio rerio 2 0.7121
Neocarzinostatin P0A3R9 NCZS_STRCZ Streptomyces carzinostaticus 2 0.7119
Neocarzinostatin P0A3R9 NCZS_STRCZ Streptomyces carzinostaticus 2 0.7119
Abscisic acid receptor PYL2 O80992 PYL2_ARATH Arabidopsis thaliana 2 0.7117
Abscisic acid receptor PYL2 O80992 PYL2_ARATH Arabidopsis thaliana 2 0.7117
Plasma membrane ATPase Q42932 Q42932_NICPL Nicotiana plumbaginifolia 2 0.7114
Plasma membrane ATPase Q42932 Q42932_NICPL Nicotiana plumbaginifolia 2 0.7114
Steroid Delta-isomerase P07445 SDIS_PSEPU Pseudomonas putida 2 0.7113
Steroid Delta-isomerase P07445 SDIS_PSEPU Pseudomonas putida 2 0.7113
HTH-type transcriptional repressor PurR P0ACP7 PURR_ECOLI Escherichia coli 2 0.7110
HTH-type transcriptional repressor PurR P0ACP7 PURR_ECOLI Escherichia coli 2 0.7110
Pheromone-binding protein ASP1 Q9U9J6 Q9U9J6_APIME Apis mellifera 2 0.7109
Pheromone-binding protein ASP1 Q9U9J6 Q9U9J6_APIME Apis mellifera 2 0.7109
Steroid 17-alpha-hydroxylase/17,20 lyase P05093 CP17A_HUMAN Homo sapiens 2 0.7103
Steroid 17-alpha-hydroxylase/17,20 lyase P05093 CP17A_HUMAN Homo sapiens 2 0.7103
Cyclin-dependent kinase 2 P24941 CDK2_HUMAN Homo sapiens 2 0.7101
Cyclin-dependent kinase 2 P24941 CDK2_HUMAN Homo sapiens 2 0.7101
Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase Q9TQS6 DHDH_MACFA Macaca fascicularis 2 0.7100
Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase Q9TQS6 DHDH_MACFA Macaca fascicularis 2 0.7100
L-seryl-tRNA(Sec) kinase Q58933 PSTK_METJA Methanocaldococcus jannaschii 2 0.7082
L-seryl-tRNA(Sec) kinase Q58933 PSTK_METJA Methanocaldococcus jannaschii 2 0.7082
cAMP-dependent protein kinase type I-alpha regulatory subunit P00514 KAP0_BOVIN Bos taurus 2 0.7081
cAMP-dependent protein kinase type I-alpha regulatory subunit P00514 KAP0_BOVIN Bos taurus 2 0.7081
Flavin-dependent thymidylate synthase Q9WYT0 THYX_THEMA Thermotoga maritima 2 0.7077
Flavin-dependent thymidylate synthase Q9WYT0 THYX_THEMA Thermotoga maritima 2 0.7077
DNA polymerase III subunit epsilon P03007 DPO3E_ECOLI Escherichia coli 2 0.7076
DNA polymerase III subunit epsilon P03007 DPO3E_ECOLI Escherichia coli 2 0.7076
17-beta-hydroxysteroid dehydrogenase type 1 P14061 DHB1_HUMAN Homo sapiens 2 0.7076
17-beta-hydroxysteroid dehydrogenase type 1 P14061 DHB1_HUMAN Homo sapiens 2 0.7076
Cytochrome P450 monooxygenase Q5YNS8 Q5YNS8_NOCFA Nocardia farcinica 2 0.7073
Cytochrome P450 monooxygenase Q5YNS8 Q5YNS8_NOCFA Nocardia farcinica 2 0.7073
Retinoic acid receptor RXR-alpha P19793 RXRA_HUMAN Homo sapiens 3 0.7064
Retinoic acid receptor RXR-alpha P19793 RXRA_HUMAN Homo sapiens 3 0.7064
Aldo-keto reductase family 1 member D1 P51857 AK1D1_HUMAN Homo sapiens 2 0.7062
Aldo-keto reductase family 1 member D1 P51857 AK1D1_HUMAN Homo sapiens 2 0.7062
Photosynthetic reaction center cytochrome c subunit P07173 CYCR_BLAVI Blastochloris viridis 2 0.7061
Photosynthetic reaction center cytochrome c subunit P07173 CYCR_BLAVI Blastochloris viridis 2 0.7061
Beta-glucosidase 12 B8AVF0 BGL12_ORYSI Oryza sativa subsp. indica 2 0.7057
Beta-glucosidase 12 B8AVF0 BGL12_ORYSI Oryza sativa subsp. indica 2 0.7057
Nuclear receptor subfamily 1 group I member 3 O35627 NR1I3_MOUSE Mus musculus 2 0.7048
Nuclear receptor subfamily 1 group I member 3 O35627 NR1I3_MOUSE Mus musculus 2 0.7048
Retinol-binding protein 4 P18902 RET4_BOVIN Bos taurus 3 0.7047
Retinol-binding protein 4 P18902 RET4_BOVIN Bos taurus 3 0.7047
cAMP-dependent protein kinase type I-alpha regulatory subunit P00514 KAP0_BOVIN Bos taurus 2 0.7038
cAMP-dependent protein kinase type I-alpha regulatory subunit P00514 KAP0_BOVIN Bos taurus 2 0.7038
High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A O76083 PDE9A_HUMAN Homo sapiens 2 0.7037
High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A O76083 PDE9A_HUMAN Homo sapiens 2 0.7037
Albumin P02768 ALBU_HUMAN Homo sapiens 2 0.7034
Albumin P02768 ALBU_HUMAN Homo sapiens 2 0.7034
Cytochrome P450 monooxygenase Q5YNS8 Q5YNS8_NOCFA Nocardia farcinica 2 0.7032
Cytochrome P450 monooxygenase Q5YNS8 Q5YNS8_NOCFA Nocardia farcinica 2 0.7032
Retinoic acid receptor RXR-alpha P19793 RXRA_HUMAN Homo sapiens 3 0.7030
Retinoic acid receptor RXR-alpha P19793 RXRA_HUMAN Homo sapiens 3 0.7030
Pancreatic alpha-amylase P04746 AMYP_HUMAN Homo sapiens 2 0.7024
Pancreatic alpha-amylase P04746 AMYP_HUMAN Homo sapiens 2 0.7024
Purine nucleoside phosphorylase P00491 PNPH_HUMAN Homo sapiens 2 0.7020
Purine nucleoside phosphorylase P00491 PNPH_HUMAN Homo sapiens 2 0.7020
HTH-type transcriptional repressor PurR P0ACP7 PURR_ECOLI Escherichia coli 2 0.7017
HTH-type transcriptional repressor PurR P0ACP7 PURR_ECOLI Escherichia coli 2 0.7017
Thyroid hormone receptor alpha P04625 THA_CHICK Gallus gallus 3 0.7006
Thyroid hormone receptor alpha P04625 THA_CHICK Gallus gallus 3 0.7006
Genome polyprotein O92972 POLG_HCVJ4 Hepatitis C virus genotype 1b 2 0.7005
Genome polyprotein O92972 POLG_HCVJ4 Hepatitis C virus genotype 1b 2 0.7005
ActVA 6 protein Q53908 Q53908_STRCH Streptomyces coelicolor 2 0.7005
ActVA 6 protein Q53908 Q53908_STRCH Streptomyces coelicolor 2 0.7005
Retinol-binding protein 1 P02696 RET1_RAT Rattus norvegicus 3 0.7004
Retinol-binding protein 1 P02696 RET1_RAT Rattus norvegicus 3 0.7004
Photosynthetic reaction center cytochrome c subunit P07173 CYCR_BLAVI Blastochloris viridis 2 0.7003
Photosynthetic reaction center cytochrome c subunit P07173 CYCR_BLAVI Blastochloris viridis 2 0.7003
Heat shock protein HSP 90-alpha P07900 HS90A_HUMAN Homo sapiens 2 0.7002
Heat shock protein HSP 90-alpha P07900 HS90A_HUMAN Homo sapiens 2 0.7002
Glycogen synthase kinase-3 beta P49841 GSK3B_HUMAN Homo sapiens 2 0.7001
Glycogen synthase kinase-3 beta P49841 GSK3B_HUMAN Homo sapiens 2 0.7001

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