5,7-dihydroxy-2',4',5'-trimethoxyisoflavone - Compound Card

5,7-dihydroxy-2',4',5'-trimethoxyisoflavone

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5,7-dihydroxy-2',4',5'-trimethoxyisoflavone

Structure
Zoomed Structure
  • Family: Plantae - Leguminosae/Fabaceae
  • Kingdom: Plantae
  • Class: Flavonoid
    • Subclass: Isoflavone
Canonical Smiles COc1cc(OC)c(cc1c1coc2c(c1=O)c(O)cc(c2)O)OC
InChI InChI=1S/C18H16O7/c1-22-13-7-15(24-3)14(23-2)6-10(13)11-8-25-16-5-9(19)4-12(20)17(16)18(11)21/h4-8,19-20H,1-3H3
InChIKey JLYUMUHNYLUAKZ-UHFFFAOYSA-N
Formula C18H16O7
HBA 7
HBD 2
MW 344.32
Rotatable Bonds 4
TPSA 98.36
LogP 2.9
Number Rings 3
Number Aromatic Rings 3
Heavy Atom Count 25
Formal Charge 0
Fraction CSP3 0.17
Exact Mass 344.09
Number of Lipinski Rule Violations 0
# Species Family Kingdom NCBI Taxonomy ID
1 Erythrina sacleuxii Leguminosae/Fabaceae Plantae 1899109
2 Erythrina sacleuxii Leguminosae/Fabaceae Plantae 1899109

Showing of synonyms

  • Andayi AW, Yenesew A, et al. (2006). Antiplasmodial flavonoids from Erythrina sacleuxii.. Planta Medica,2006,72(2),187-189. [View] [PubMed]
  • Yenesew A, Midiwo JO, et al. (1998). Four isoflavones from the stem bark of erythrina sacleuxii. Phytochemistry,1998,49(1),247-249. [View] [PubMed]
Pubchem: 7330538
Nmrshiftdb2: 60068534

No compound-protein relationship available.

Structure

SMILES: c1cccc(c12)occ(c2=O)-c3ccccc3

Level: 1

Mol. Weight: 344.32 g/mol

Structure

SMILES: c1cccc(c12)occc2=O

Level: 0

Mol. Weight: 344.32 g/mol

Structure

SMILES: c1ccccc1

Level: 0

Mol. Weight: 344.32 g/mol

Anti-plasmodial

Absorption

Caco-2 (logPapp)
-4.54
Human Oral Bioavailability 20%
Bioavailable
Human Intestinal Absorption
Absorbed
Madin-Darby Canine Kidney
-4.840
Human Oral Bioavailability 50%
Bioavailable
P-Glycoprotein Inhibitor
Inhibitor
P-Glycoprotein Substrate
Non-Substrate
Skin Permeability
-1.02

Distribution

Blood-Brain Barrier (CNS)
-
Blood-Brain Barrier
Non-Penetrable
Fraction Unbound (Human)
1.300
Plasma Protein Binding
81.87
Steady State Volume of Distribution
-

Metabolism

Breast Cancer Resistance Protein
Inhibitor
CYP 1A2 Inhibitor
Inhibitor
CYP 1A2 Substrate
Substrate
CYP 2C19 Inhibitor
Inhibitor
CYP 2C19 Substrate
Non-Substrate
CYP 2C9 Inhibitor
Non-Inhibitor
CYP 2C9 Substrate
Substrate
CYP 2D6 Inhibitor
Inhibitor
CYP 2D6 Substrate
Non-Substrate
CYP 3A4 Inhibitor
Inhibitor
CYP 3A4 Substrate
Non-Substrate
OATP1B1
Non-Inhibitor
OATP1B3
Non-Inhibitor

Excretion

Clearance
7.020
Organic Cation Transporter 2
Inhibitor
Half-Life of Drug
-

Toxicity

AMES Mutagenesis
Safe
Avian
Safe
Bee
Toxic
Bioconcentration Factor
2.060
Biodegradation
Safe
Carcinogenesis
Safe
Crustacean
Toxic
Liver Injury I (DILI)
Toxic
Eye Corrosion
Safe
Eye Irritation
Toxic
Maximum Tolerated Dose
1.260
Liver Injury II
Toxic
hERG Blockers
Safe
Daphnia Maga
5.730
Micronucleos
Toxic
NR-AhR
Toxic
NR-AR
Safe
NR-AR-LBD
Safe
NR-Aromatase
Safe
NR-ER
Safe
NR-ER-LBD
Safe
NR-GR
Safe
NR-PPAR-gamma
Safe
NR-TR
Toxic
T. Pyriformis
1.870
Rat (Acute)
2.160
Rat (Chronic Oral)
2.540
Fathead Minnow
4.950
Respiratory Disease
Toxic
Skin Sensitisation
Safe
SR-ARE
Toxic
SR-ATAD5
Safe
SR-HSE
Safe
SR-MMP
Toxic
SR-p53
Toxic

General Properties

Boiling Point
464.980
Hydration Free Energy
-10.660
Log(D) at pH=7.4
3.350
Log(P)
3.11
Log S
-5.9
Log(Vapor Pressure)
-7.84
Melting Point
205.62
pKa Acid
8.09
pKa Basic
3.34
Protein Name UniProt ID Entry Name Species #Pharmacophore Points Probability (0.7 ≤ Tversky Score ≤ 1.0)
Serine/threonine-protein kinase 24 Q9Y6E0 STK24_HUMAN Homo sapiens 3 0.9643
Serine/threonine-protein kinase 24 Q9Y6E0 STK24_HUMAN Homo sapiens 3 0.9643
IOMT 3 Q06YR3 Q06YR3_MEDTR Medicago truncatula 4 0.9487
IOMT 3 Q06YR3 Q06YR3_MEDTR Medicago truncatula 4 0.9487
Heat shock protein HSP 90-alpha P07900 HS90A_HUMAN Homo sapiens 3 0.9432
Heat shock protein HSP 90-alpha P07900 HS90A_HUMAN Homo sapiens 3 0.9432
Serine/threonine-protein kinase 10 O94804 STK10_HUMAN Homo sapiens 3 0.9375
Serine/threonine-protein kinase 10 O94804 STK10_HUMAN Homo sapiens 3 0.9375
3',5'-cyclic-AMP phosphodiesterase 4D Q08499 PDE4D_HUMAN Homo sapiens 3 0.9323
3',5'-cyclic-AMP phosphodiesterase 4D Q08499 PDE4D_HUMAN Homo sapiens 3 0.9323
NAD-capped RNA hydrolase NudC P32664 NUDC_ECOLI Escherichia coli 3 0.9245
NAD-capped RNA hydrolase NudC P32664 NUDC_ECOLI Escherichia coli 3 0.9245
Ribosomal small subunit pseudouridine synthase A P0AA43 RSUA_ECOLI Escherichia coli 3 0.9238
Ribosomal small subunit pseudouridine synthase A P0AA43 RSUA_ECOLI Escherichia coli 3 0.9238
Chitinase A Q9AMP1 Q9AMP1_VIBHA Vibrio harveyi 3 0.9216
Chitinase A Q9AMP1 Q9AMP1_VIBHA Vibrio harveyi 3 0.9216
Biflaviolin synthase CYP158A1 Q9KZF5 C1581_STRCO Streptomyces coelicolor / M145) 3 0.9195
Biflaviolin synthase CYP158A1 Q9KZF5 C1581_STRCO Streptomyces coelicolor / M145) 3 0.9195
Epidermal growth factor receptor P00533 EGFR_HUMAN Homo sapiens 3 0.9168
Epidermal growth factor receptor P00533 EGFR_HUMAN Homo sapiens 3 0.9168
Toxoflavin degrading enzyme E3SET7 E3SET7_PAEPO Paenibacillus polymyxa 3 0.9166
Toxoflavin degrading enzyme E3SET7 E3SET7_PAEPO Paenibacillus polymyxa 3 0.9166
Estrogen receptor P03372 ESR1_HUMAN Homo sapiens 4 0.9150
Estrogen receptor P03372 ESR1_HUMAN Homo sapiens 4 0.9150
HTH-type transcriptional regulator TtgR Q9AIU0 TTGR_PSEPT Pseudomonas putida 3 0.9117
HTH-type transcriptional regulator TtgR Q9AIU0 TTGR_PSEPT Pseudomonas putida 3 0.9117
Estrogen receptor P03372 ESR1_HUMAN Homo sapiens 4 0.9104
Estrogen receptor P03372 ESR1_HUMAN Homo sapiens 4 0.9104
Thymidylate synthase P00469 TYSY_LACCA Lacticaseibacillus casei 3 0.9050
Thymidylate synthase P00469 TYSY_LACCA Lacticaseibacillus casei 3 0.9050
Nitric oxide synthase oxygenase O34453 NOSO_BACSU Bacillus subtilis 4 0.9047
Nitric oxide synthase oxygenase O34453 NOSO_BACSU Bacillus subtilis 4 0.9047
Epidermal growth factor receptor P00533 EGFR_HUMAN Homo sapiens 3 0.9041
Epidermal growth factor receptor P00533 EGFR_HUMAN Homo sapiens 3 0.9041
Dihydrofolate reductase P22906 DYR_CANAX Candida albicans 4 0.9003
Dihydrofolate reductase P22906 DYR_CANAX Candida albicans 4 0.9003
Transthyretin P02766 TTHY_HUMAN Homo sapiens 4 0.8997
Transthyretin P02766 TTHY_HUMAN Homo sapiens 4 0.8997
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase Q8DNV6 Q8DNV6_STRR6 Streptococcus pneumoniae 3 0.8780
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase Q8DNV6 Q8DNV6_STRR6 Streptococcus pneumoniae 3 0.8780
Bromodomain-containing protein 2 P25440 BRD2_HUMAN Homo sapiens 3 0.8778
Bromodomain-containing protein 2 P25440 BRD2_HUMAN Homo sapiens 3 0.8778
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A Q9Y233 PDE10_HUMAN Homo sapiens 3 0.8753
Tetracycline repressor protein class H P51561 TETR8_PASMD Pasteurella multocida 3 0.8753
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A Q9Y233 PDE10_HUMAN Homo sapiens 3 0.8753
Tetracycline repressor protein class H P51561 TETR8_PASMD Pasteurella multocida 3 0.8753
Aldo-keto reductase family 1 member B1 P15121 ALDR_HUMAN Homo sapiens 3 0.8733
Aldo-keto reductase family 1 member B1 P15121 ALDR_HUMAN Homo sapiens 3 0.8733
Steroid Delta-isomerase P00947 SDIS_COMTE Comamonas testosteroni 3 0.8732
Steroid Delta-isomerase P00947 SDIS_COMTE Comamonas testosteroni 3 0.8732
Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase Q9TQS6 DHDH_MACFA Macaca fascicularis 3 0.8727
Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase Q9TQS6 DHDH_MACFA Macaca fascicularis 3 0.8727
Histone deacetylase 4 P56524 HDAC4_HUMAN Homo sapiens 3 0.8725
Histone deacetylase 4 P56524 HDAC4_HUMAN Homo sapiens 3 0.8725
Steroid Delta-isomerase P00947 SDIS_COMTE Comamonas testosteroni 3 0.8696
Steroid Delta-isomerase P00947 SDIS_COMTE Comamonas testosteroni 3 0.8696
Bromodomain-containing protein 4 O60885 BRD4_HUMAN Homo sapiens 4 0.8680
Bromodomain-containing protein 4 O60885 BRD4_HUMAN Homo sapiens 4 0.8680
Tetracycline repressor protein class D P0ACT4 TETR4_ECOLX Escherichia coli 3 0.8669
Tetracycline repressor protein class D P0ACT4 TETR4_ECOLX Escherichia coli 3 0.8669
Isoflavone-7-O-methyltransferase 8 O24529 7OMT8_MEDSA Medicago sativa 5 0.8621
Isoflavone-7-O-methyltransferase 8 O24529 7OMT8_MEDSA Medicago sativa 5 0.8621
Bromodomain adjacent to zinc finger domain protein 2B Q9UIF8 BAZ2B_HUMAN Homo sapiens 3 0.8617
Bromodomain adjacent to zinc finger domain protein 2B Q9UIF8 BAZ2B_HUMAN Homo sapiens 3 0.8617
Biotin carboxylase P24182 ACCC_ECOLI Escherichia coli 4 0.8544
Biotin carboxylase P24182 ACCC_ECOLI Escherichia coli 4 0.8544
Transthyretin P02767 TTHY_RAT Rattus norvegicus 3 0.8533
Transthyretin P02767 TTHY_RAT Rattus norvegicus 3 0.8533
Steroid C26-monooxygenase P9WPP1 CP125_MYCTU Mycobacterium tuberculosis 3 0.8513
Steroid C26-monooxygenase P9WPP1 CP125_MYCTU Mycobacterium tuberculosis 3 0.8513
Pteridine reductase, putative Q581W1 Q581W1_TRYB2 Trypanosoma brucei brucei 4 0.8481
Pteridine reductase, putative Q581W1 Q581W1_TRYB2 Trypanosoma brucei brucei 4 0.8481
Cyclin-dependent kinase 2 P24941 CDK2_HUMAN Homo sapiens 3 0.8476
Cyclin-dependent kinase 2 P24941 CDK2_HUMAN Homo sapiens 3 0.8476
Nodulin-13 P93330 NOD13_MEDTR Medicago truncatula 3 0.8474
Nodulin-13 P93330 NOD13_MEDTR Medicago truncatula 3 0.8474
Cytochrome P450 1A1 P04798 CP1A1_HUMAN Homo sapiens 3 0.8458
Cytochrome P450 1A1 P04798 CP1A1_HUMAN Homo sapiens 3 0.8458
High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A O76083 PDE9A_HUMAN Homo sapiens 3 0.8444
High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A O76083 PDE9A_HUMAN Homo sapiens 3 0.8444
Bromodomain-containing protein 4 O60885 BRD4_HUMAN Homo sapiens 4 0.8407
Bromodomain-containing protein 4 O60885 BRD4_HUMAN Homo sapiens 4 0.8407
Biphenyl-2,3-diol 1,2-dioxygenase P17297 BPHC_PSES1 Pseudomonas sp 3 0.8404
Biphenyl-2,3-diol 1,2-dioxygenase P17297 BPHC_PSES1 Pseudomonas sp 3 0.8404
Casein kinase II subunit alpha P68400 CSK21_HUMAN Homo sapiens 5 0.8396
Casein kinase II subunit alpha P68400 CSK21_HUMAN Homo sapiens 5 0.8396
Gag-Pol polyprotein P12497 POL_HV1N5 Human immunodeficiency virus type 1 group M subtype B 3 0.8389
Gag-Pol polyprotein P12497 POL_HV1N5 Human immunodeficiency virus type 1 group M subtype B 3 0.8389
17beta-hydroxysteroid dehydrogenase O93874 O93874_COCLU Cochliobolus lunatus 4 0.8369
17beta-hydroxysteroid dehydrogenase O93874 O93874_COCLU Cochliobolus lunatus 4 0.8369
Casein kinase II subunit alpha P68400 CSK21_HUMAN Homo sapiens 3 0.8359
Casein kinase II subunit alpha P68400 CSK21_HUMAN Homo sapiens 3 0.8359
D-aminoacyl-tRNA deacylase Q8IIS0 DTD_PLAF7 Plasmodium falciparum 3 0.8355
D-aminoacyl-tRNA deacylase Q8IIS0 DTD_PLAF7 Plasmodium falciparum 3 0.8355
ATP-dependent molecular chaperone HSP82 P02829 HSP82_YEAST Saccharomyces cerevisiae 3 0.8353
ATP-dependent molecular chaperone HSP82 P02829 HSP82_YEAST Saccharomyces cerevisiae 3 0.8353
Peroxisome proliferator-activated receptor gamma P37231 PPARG_HUMAN Homo sapiens 4 0.8349
Peroxisome proliferator-activated receptor gamma P37231 PPARG_HUMAN Homo sapiens 4 0.8349
Heat shock protein HSP 90-alpha P07900 HS90A_HUMAN Homo sapiens 3 0.8330
Heat shock protein HSP 90-alpha P07900 HS90A_HUMAN Homo sapiens 3 0.8330
Serine/threonine-protein kinase 24 Q9Y6E0 STK24_HUMAN Homo sapiens 3 0.8320
Serine/threonine-protein kinase 24 Q9Y6E0 STK24_HUMAN Homo sapiens 3 0.8320
Peroxisome proliferator-activated receptor gamma P37231 PPARG_HUMAN Homo sapiens 3 0.8315
Peroxisome proliferator-activated receptor gamma P37231 PPARG_HUMAN Homo sapiens 3 0.8315
Chalcone--flavanone isomerase 1 P28012 CFI1_MEDSA Medicago sativa 3 0.8296
Chalcone--flavanone isomerase 1 P28012 CFI1_MEDSA Medicago sativa 3 0.8296
Tetracycline repressor protein class D P0ACT4 TETR4_ECOLX Escherichia coli 3 0.8260
Tetracycline repressor protein class D P0ACT4 TETR4_ECOLX Escherichia coli 3 0.8260
Neocarzinostatin P0A3R9 NCZS_STRCZ Streptomyces carzinostaticus 3 0.8248
Neocarzinostatin P0A3R9 NCZS_STRCZ Streptomyces carzinostaticus 3 0.8248
Pteridine reductase O76290 O76290_TRYBB Trypanosoma brucei brucei 3 0.8236
Pteridine reductase O76290 O76290_TRYBB Trypanosoma brucei brucei 3 0.8236
Tetracycline repressor protein class D P0ACT4 TETR4_ECOLX Escherichia coli 3 0.8229
Tetracycline repressor protein class D P0ACT4 TETR4_ECOLX Escherichia coli 3 0.8229
Proliferating cell nuclear antigen P12004 PCNA_HUMAN Homo sapiens 3 0.8180
Proliferating cell nuclear antigen P12004 PCNA_HUMAN Homo sapiens 3 0.8180
Tyrosine-protein kinase Lck P06239 LCK_HUMAN Homo sapiens 4 0.8180
Tyrosine-protein kinase Lck P06239 LCK_HUMAN Homo sapiens 4 0.8180
Sulfide-quinone reductase B7JBP8 SQRD_ACIF2 Acidithiobacillus ferrooxidans) 3 0.8173
Sulfide-quinone reductase B7JBP8 SQRD_ACIF2 Acidithiobacillus ferrooxidans) 3 0.8173
Mitogen-activated protein kinase 8 P45983 MK08_HUMAN Homo sapiens 3 0.8141
Mitogen-activated protein kinase 8 P45983 MK08_HUMAN Homo sapiens 3 0.8141
Mycocyclosin synthase P9WPP7 CP121_MYCTU Mycobacterium tuberculosis 3 0.8112
Mycocyclosin synthase P9WPP7 CP121_MYCTU Mycobacterium tuberculosis 3 0.8112
Death-associated protein kinase 1 P53355 DAPK1_HUMAN Homo sapiens 4 0.8101
Death-associated protein kinase 1 P53355 DAPK1_HUMAN Homo sapiens 4 0.8101
Cis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase Q46381 BPHB_COMTE Comamonas testosteroni 3 0.8036
Cis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase Q46381 BPHB_COMTE Comamonas testosteroni 3 0.8036
Pantothenate synthetase P9WIL5 PANC_MYCTU Mycobacterium tuberculosis 3 0.7996
Pantothenate synthetase P9WIL5 PANC_MYCTU Mycobacterium tuberculosis 3 0.7996
DNA gyrase subunit A P0AES5 GYRA_SHIFL Shigella flexneri 3 0.7982
DNA gyrase subunit A P0AES5 GYRA_SHIFL Shigella flexneri 3 0.7982
Biflaviolin synthase CYP158A2 Q9FCA6 C1582_STRCO Streptomyces coelicolor / M145) 3 0.7968
Biflaviolin synthase CYP158A2 Q9FCA6 C1582_STRCO Streptomyces coelicolor / M145) 3 0.7968
Glutathione S-transferase F2 P46422 GSTF2_ARATH Arabidopsis thaliana 3 0.7960
Dipeptidyl peptidase 4 P27487 DPP4_HUMAN Homo sapiens 3 0.7960
Glutathione S-transferase F2 P46422 GSTF2_ARATH Arabidopsis thaliana 3 0.7960
Dipeptidyl peptidase 4 P27487 DPP4_HUMAN Homo sapiens 3 0.7960
Capsid protein Q9WBP8 Q9WBP8_9VIRU Adeno-associated virus - 1 3 0.7927
Capsid protein Q9WBP8 Q9WBP8_9VIRU Adeno-associated virus - 1 3 0.7927
Aldehyde dehydrogenase, mitochondrial P05091 ALDH2_HUMAN Homo sapiens 4 0.7881
Aldehyde dehydrogenase, mitochondrial P05091 ALDH2_HUMAN Homo sapiens 4 0.7881
Major pollen allergen Bet v 1-A P15494 BEV1A_BETPN Betula pendula 3 0.7877
Major pollen allergen Bet v 1-A P15494 BEV1A_BETPN Betula pendula 3 0.7877
Carbonic anhydrase 2 P00918 CAH2_HUMAN Homo sapiens 3 0.7875
Carbonic anhydrase 2 P00918 CAH2_HUMAN Homo sapiens 3 0.7875
Genome polyprotein Q2YHF0 POLG_DEN4T Dengue virus type 4 3 0.7872
Genome polyprotein Q2YHF0 POLG_DEN4T Dengue virus type 4 3 0.7872
Isoleucine--tRNA ligase P56690 SYI_THET8 Thermus thermophilus 3 0.7855
Isoleucine--tRNA ligase P56690 SYI_THET8 Thermus thermophilus 3 0.7855
Heat shock protein HSP 90-alpha P07900 HS90A_HUMAN Homo sapiens 3 0.7849
Heat shock protein HSP 90-alpha P07900 HS90A_HUMAN Homo sapiens 3 0.7849
Protoporphyrinogen oxidase P50336 PPOX_HUMAN Homo sapiens 3 0.7825
Protoporphyrinogen oxidase P50336 PPOX_HUMAN Homo sapiens 3 0.7825
Biotin carboxylase P24182 ACCC_ECOLI Escherichia coli 4 0.7823
Biotin carboxylase P24182 ACCC_ECOLI Escherichia coli 4 0.7823
Reaction center protein L chain P0C0Y7 RCEH_RHOSH Rhodobacter sphaeroides 3 0.7811
Reaction center protein L chain P0C0Y7 RCEH_RHOSH Rhodobacter sphaeroides 3 0.7811
Acetolactate synthase, chloroplastic P17597 ILVB_ARATH Arabidopsis thaliana 3 0.7787
Acetolactate synthase, chloroplastic P17597 ILVB_ARATH Arabidopsis thaliana 3 0.7787
Gag-Pol polyprotein P03367 POL_HV1BR Human immunodeficiency virus type 1 group M subtype B 3 0.7775
Gag-Pol polyprotein P03367 POL_HV1BR Human immunodeficiency virus type 1 group M subtype B 3 0.7775
Serine/threonine-protein kinase Chk1 O14757 CHK1_HUMAN Homo sapiens 3 0.7764
Serine/threonine-protein kinase Chk1 O14757 CHK1_HUMAN Homo sapiens 3 0.7764
Polyprotein Q80J95 Q80J95_9CALI Murine norovirus 1 3 0.7758
Polyprotein Q80J95 Q80J95_9CALI Murine norovirus 1 3 0.7758
Beta-secretase 1 P56817 BACE1_HUMAN Homo sapiens 3 0.7756
Beta-secretase 1 P56817 BACE1_HUMAN Homo sapiens 3 0.7756
Nuclear receptor subfamily 1 group I member 2 O75469 NR1I2_HUMAN Homo sapiens 3 0.7751
Nuclear receptor subfamily 1 group I member 2 O75469 NR1I2_HUMAN Homo sapiens 3 0.7751
Proto-oncogene tyrosine-protein kinase Src P00523 SRC_CHICK Gallus gallus 3 0.7747
Proto-oncogene tyrosine-protein kinase Src P00523 SRC_CHICK Gallus gallus 3 0.7747
Tetracycline repressor protein class D P0ACT4 TETR4_ECOLX Escherichia coli 3 0.7742
Tetracycline repressor protein class D P0ACT4 TETR4_ECOLX Escherichia coli 3 0.7742
Fibroblast growth factor receptor 1 P11362 FGFR1_HUMAN Homo sapiens 3 0.7730
Fibroblast growth factor receptor 1 P11362 FGFR1_HUMAN Homo sapiens 3 0.7730
Gag-Pol polyprotein P12497 POL_HV1N5 Human immunodeficiency virus type 1 group M subtype B 3 0.7696
Gag-Pol polyprotein P12497 POL_HV1N5 Human immunodeficiency virus type 1 group M subtype B 3 0.7696
Heat shock protein HSP 90-alpha P07900 HS90A_HUMAN Homo sapiens 3 0.7693
Heat shock protein HSP 90-alpha P07900 HS90A_HUMAN Homo sapiens 3 0.7693
Chalcone--flavanone isomerase 1 P28012 CFI1_MEDSA Medicago sativa 3 0.7673
Chalcone--flavanone isomerase 1 P28012 CFI1_MEDSA Medicago sativa 3 0.7673
Chalcone--flavanone isomerase 1 P28012 CFI1_MEDSA Medicago sativa 3 0.7673
Serine/threonine-protein kinase Chk1 O14757 CHK1_HUMAN Homo sapiens 4 0.7673
Serine/threonine-protein kinase Chk1 O14757 CHK1_HUMAN Homo sapiens 4 0.7673
Chalcone--flavanone isomerase 1 P28012 CFI1_MEDSA Medicago sativa 3 0.7673
Carbonic anhydrase 2 P00918 CAH2_HUMAN Homo sapiens 2 0.7669
Carbonic anhydrase 2 P00918 CAH2_HUMAN Homo sapiens 2 0.7669
Heat shock protein HSP 90-alpha P07900 HS90A_HUMAN Homo sapiens 3 0.7646
Heat shock protein HSP 90-alpha P07900 HS90A_HUMAN Homo sapiens 3 0.7646
Lethal(3)malignant brain tumor-like protein 1 Q9Y468 LMBL1_HUMAN Homo sapiens 3 0.7640
Lethal(3)malignant brain tumor-like protein 1 Q9Y468 LMBL1_HUMAN Homo sapiens 3 0.7640
Soluble cytochrome b562 P0ABE7 C562_ECOLX Escherichia coli 3 0.7635
Soluble cytochrome b562 P0ABE7 C562_ECOLX Escherichia coli 3 0.7635
Succinate dehydrogenase flavoprotein subunit P0AC41 SDHA_ECOLI Escherichia coli 3 0.7629
Succinate dehydrogenase flavoprotein subunit P0AC41 SDHA_ECOLI Escherichia coli 3 0.7629
Death-associated protein kinase 1 P53355 DAPK1_HUMAN Homo sapiens 4 0.7628
Death-associated protein kinase 1 P53355 DAPK1_HUMAN Homo sapiens 4 0.7628
High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A O76083 PDE9A_HUMAN Homo sapiens 3 0.7624
High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A O76083 PDE9A_HUMAN Homo sapiens 3 0.7624
Lactotransferrin P24627 TRFL_BOVIN Bos taurus 2 0.7621
Lactotransferrin P24627 TRFL_BOVIN Bos taurus 2 0.7621
Carbonic anhydrase 2 P00918 CAH2_HUMAN Homo sapiens 2 0.7608
Carbonic anhydrase 2 P00918 CAH2_HUMAN Homo sapiens 2 0.7608
Tubulin alpha chain D0VWZ0 D0VWZ0_SHEEP Ovis aries 3 0.7585
Tubulin alpha chain D0VWZ0 D0VWZ0_SHEEP Ovis aries 3 0.7585
Tau-tubulin kinase 1 Q5TCY1 TTBK1_HUMAN Homo sapiens 3 0.7553
Tau-tubulin kinase 1 Q5TCY1 TTBK1_HUMAN Homo sapiens 3 0.7553
Acetolactate synthase, chloroplastic P17597 ILVB_ARATH Arabidopsis thaliana 3 0.7535
Acetolactate synthase, chloroplastic P17597 ILVB_ARATH Arabidopsis thaliana 3 0.7535
HTH-type transcriptional regulator TtgR Q9AIU0 TTGR_PSEPT Pseudomonas putida 3 0.7534
HTH-type transcriptional regulator TtgR Q9AIU0 TTGR_PSEPT Pseudomonas putida 3 0.7534
Ephrin type-A receptor 4 Q03137 EPHA4_MOUSE Mus musculus 4 0.7514
Ephrin type-A receptor 4 Q03137 EPHA4_MOUSE Mus musculus 4 0.7514
Succinate dehydrogenase flavoprotein subunit P0AC41 SDHA_ECOLI Escherichia coli 3 0.7504
Succinate dehydrogenase flavoprotein subunit P0AC41 SDHA_ECOLI Escherichia coli 3 0.7504
Death-associated protein kinase 1 P53355 DAPK1_HUMAN Homo sapiens 4 0.7496
Death-associated protein kinase 1 P53355 DAPK1_HUMAN Homo sapiens 4 0.7496
Rhodopsin kinase GRK1 P28327 GRK1_BOVIN Bos taurus 3 0.7495
Rhodopsin kinase GRK1 P28327 GRK1_BOVIN Bos taurus 3 0.7495
Streptavidin P22629 SAV_STRAV Streptomyces avidinii 4 0.7494
Streptavidin P22629 SAV_STRAV Streptomyces avidinii 4 0.7494
Mitogen-activated protein kinase 14 Q16539 MK14_HUMAN Homo sapiens 3 0.7490
Mitogen-activated protein kinase 14 Q16539 MK14_HUMAN Homo sapiens 3 0.7490
Valacyclovir hydrolase Q86WA6 BPHL_HUMAN Homo sapiens 3 0.7488
Valacyclovir hydrolase Q86WA6 BPHL_HUMAN Homo sapiens 3 0.7488
Bromodomain-containing protein 4 O60885 BRD4_HUMAN Homo sapiens 3 0.7485
Bromodomain-containing protein 4 O60885 BRD4_HUMAN Homo sapiens 3 0.7485
Biflaviolin synthase CYP158A2 Q9FCA6 C1582_STRCO Streptomyces coelicolor / M145) 3 0.7479
Biflaviolin synthase CYP158A2 Q9FCA6 C1582_STRCO Streptomyces coelicolor / M145) 3 0.7479
Basic phospholipase A2 VRV-PL-VIIIa P59071 PA2B8_DABRR Daboia russelii 2 0.7473
Basic phospholipase A2 VRV-PL-VIIIa P59071 PA2B8_DABRR Daboia russelii 2 0.7473
Poly [ADP-ribose] polymerase tankyrase-2 Q9H2K2 TNKS2_HUMAN Homo sapiens 3 0.7468
Poly [ADP-ribose] polymerase tankyrase-2 Q9H2K2 TNKS2_HUMAN Homo sapiens 3 0.7468
NTPase P4 Q94M05 Q94M05_9VIRU Pseudomonas phage phi12 3 0.7464
NTPase P4 Q94M05 Q94M05_9VIRU Pseudomonas phage phi12 3 0.7464
Estrogen receptor beta Q92731 ESR2_HUMAN Homo sapiens 3 0.7458
Estrogen receptor beta Q92731 ESR2_HUMAN Homo sapiens 3 0.7458
Biphenyl-2,3-diol 1,2-dioxygenase P17297 BPHC_PSES1 Pseudomonas sp 3 0.7449
Estrogen receptor beta Q92731 ESR2_HUMAN Homo sapiens 3 0.7449
Estrogen receptor beta Q92731 ESR2_HUMAN Homo sapiens 3 0.7449
Biphenyl-2,3-diol 1,2-dioxygenase P17297 BPHC_PSES1 Pseudomonas sp 3 0.7449
Gag-Pol polyprotein O12158 POL_HV192 Human immunodeficiency virus type 1 group M subtype C 3 0.7438
Gag-Pol polyprotein O12158 POL_HV192 Human immunodeficiency virus type 1 group M subtype C 3 0.7438
Serine/threonine-protein kinase pim-1 P11309 PIM1_HUMAN Homo sapiens 3 0.7426
Serine/threonine-protein kinase pim-1 P11309 PIM1_HUMAN Homo sapiens 3 0.7426
Glycogen synthase kinase-3 beta P49841 GSK3B_HUMAN Homo sapiens 3 0.7424
Glycogen synthase kinase-3 beta P49841 GSK3B_HUMAN Homo sapiens 3 0.7424
Transcriptional regulator, PadR-like family A2RI36 A2RI36_LACLM Lactococcus lactis subsp. cremoris 2 0.7418
Anthocyanidin 3-O-glucosyltransferase UFGT P51094 UFOG_VITVI Vitis vinifera 4 0.7418
Transcriptional regulator, PadR-like family A2RI36 A2RI36_LACLM Lactococcus lactis subsp. cremoris 2 0.7418
Anthocyanidin 3-O-glucosyltransferase UFGT P51094 UFOG_VITVI Vitis vinifera 4 0.7418
Homoserine dehydrogenase P31116 DHOM_YEAST Saccharomyces cerevisiae 3 0.7414
Homoserine dehydrogenase P31116 DHOM_YEAST Saccharomyces cerevisiae 3 0.7414
Gag-Pol polyprotein P04584 POL_HV2RO Human immunodeficiency virus type 2 subtype A 3 0.7409
Gag-Pol polyprotein P04584 POL_HV2RO Human immunodeficiency virus type 2 subtype A 3 0.7409
Biphenyl dioxygenase subunit alpha P37333 BPHA_PARXL Paraburkholderia xenovorans 3 0.7405
Biphenyl dioxygenase subunit alpha P37333 BPHA_PARXL Paraburkholderia xenovorans 3 0.7405
Beta-lactamase Q9L5C8 Q9L5C8_ECOLX Escherichia coli 3 0.7397
Beta-lactamase Q9L5C8 Q9L5C8_ECOLX Escherichia coli 3 0.7397
S-adenosylmethionine decarboxylase proenzyme P17707 DCAM_HUMAN Homo sapiens 3 0.7383
S-adenosylmethionine decarboxylase proenzyme P17707 DCAM_HUMAN Homo sapiens 3 0.7383
CREB-binding protein Q92793 CBP_HUMAN Homo sapiens 3 0.7382
CREB-binding protein Q92793 CBP_HUMAN Homo sapiens 3 0.7382
Bromodomain-containing protein 4 O60885 BRD4_HUMAN Homo sapiens 3 0.7380
Bromodomain-containing protein 4 O60885 BRD4_HUMAN Homo sapiens 3 0.7380
4-hydroxyphenylacetate 3-monooxygenase Q8YHT7 Q8YHT7_BRUME Brucella melitensis biotype 1 2 0.7378
4-hydroxyphenylacetate 3-monooxygenase Q8YHT7 Q8YHT7_BRUME Brucella melitensis biotype 1 2 0.7378
cGMP-specific 3',5'-cyclic phosphodiesterase O76074 PDE5A_HUMAN Homo sapiens 3 0.7364
cGMP-specific 3',5'-cyclic phosphodiesterase O76074 PDE5A_HUMAN Homo sapiens 3 0.7364
Albumin P02768 ALBU_HUMAN Homo sapiens 3 0.7334
Albumin P02768 ALBU_HUMAN Homo sapiens 3 0.7334
Gag-Pol polyprotein P04584 POL_HV2RO Human immunodeficiency virus type 2 subtype A 3 0.7330
Gag-Pol polyprotein P04584 POL_HV2RO Human immunodeficiency virus type 2 subtype A 3 0.7330
Basic phospholipase A2 VRV-PL-VIIIa P59071 PA2B8_DABRR Daboia russelii 2 0.7329
Basic phospholipase A2 VRV-PL-VIIIa P59071 PA2B8_DABRR Daboia russelii 2 0.7329
Calmodulin-like domain protein kinase isoenzyme gamma, related F0V9W9 F0V9W9_NEOCL Neospora caninum 3 0.7320
Calmodulin-like domain protein kinase isoenzyme gamma, related F0V9W9 F0V9W9_NEOCL Neospora caninum 3 0.7320
Bromodomain protein, putative Q8I240 Q8I240_PLAF7 Plasmodium falciparum 4 0.7319
Bromodomain protein, putative Q8I240 Q8I240_PLAF7 Plasmodium falciparum 4 0.7319
Basic phospholipase A2 VRV-PL-VIIIa P59071 PA2B8_DABRR Daboia russelii 3 0.7308
Basic phospholipase A2 VRV-PL-VIIIa P59071 PA2B8_DABRR Daboia russelii 3 0.7308
Cyclin-dependent kinase 9 P50750 CDK9_HUMAN Homo sapiens 3 0.7301
Cyclin-dependent kinase 9 P50750 CDK9_HUMAN Homo sapiens 3 0.7301
Carbonyl reductase [NADPH] 1 P16152 CBR1_HUMAN Homo sapiens 3 0.7299
Carbonyl reductase [NADPH] 1 P16152 CBR1_HUMAN Homo sapiens 3 0.7299
Phosphodiesterase Q8WQX9 Q8WQX9_9TRYP Trypanosoma brucei 3 0.7298
Phosphodiesterase Q8WQX9 Q8WQX9_9TRYP Trypanosoma brucei 3 0.7298
tyrosine--tRNA ligase Q4QFJ7 Q4QFJ7_LEIMA Leishmania major 3 0.7298
tyrosine--tRNA ligase Q4QFJ7 Q4QFJ7_LEIMA Leishmania major 3 0.7298
Gag-Pol polyprotein P03367 POL_HV1BR Human immunodeficiency virus type 1 group M subtype B 3 0.7292
Gag-Pol polyprotein P03367 POL_HV1BR Human immunodeficiency virus type 1 group M subtype B 3 0.7292
Serine/threonine-protein kinase PLK1 P53350 PLK1_HUMAN Homo sapiens 3 0.7290
Serine/threonine-protein kinase PLK1 P53350 PLK1_HUMAN Homo sapiens 3 0.7290
Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplastic Q43088 RBCMT_PEA Pisum sativum 4 0.7288
Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplastic Q43088 RBCMT_PEA Pisum sativum 4 0.7288
Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase Q05603 COBT_SALTY Salmonella typhimurium 2 0.7285
Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase Q05603 COBT_SALTY Salmonella typhimurium 2 0.7285
Epidermal growth factor receptor P00533 EGFR_HUMAN Homo sapiens 3 0.7281
Epidermal growth factor receptor P00533 EGFR_HUMAN Homo sapiens 3 0.7281
Retinoic acid receptor RXR-alpha P19793 RXRA_HUMAN Homo sapiens 4 0.7280
Retinoic acid receptor RXR-alpha P19793 RXRA_HUMAN Homo sapiens 4 0.7280
Riboflavin synthase P0AFU8 RISA_ECOLI Escherichia coli 3 0.7278
Riboflavin synthase P0AFU8 RISA_ECOLI Escherichia coli 3 0.7278
Nitric oxide synthase oxygenase O34453 NOSO_BACSU Bacillus subtilis 3 0.7262
Nitric oxide synthase oxygenase O34453 NOSO_BACSU Bacillus subtilis 3 0.7262
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial Q15119 PDK2_HUMAN Homo sapiens 3 0.7253
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial Q15119 PDK2_HUMAN Homo sapiens 3 0.7253
Polymerase acidic protein C3W5S0 C3W5S0_I09A0 Influenza A virus 2 0.7251
Polymerase acidic protein C3W5S0 C3W5S0_I09A0 Influenza A virus 2 0.7251
Methionine adenosyltransferase 2 subunit beta Q9NZL9 MAT2B_HUMAN Homo sapiens 4 0.7235
Methionine adenosyltransferase 2 subunit beta Q9NZL9 MAT2B_HUMAN Homo sapiens 4 0.7235
Ephrin type-B receptor 2 P54763 EPHB2_MOUSE Mus musculus 3 0.7234
Ephrin type-B receptor 2 P54763 EPHB2_MOUSE Mus musculus 3 0.7234
Tyrosine-protein kinase JAK2 O60674 JAK2_HUMAN Homo sapiens 3 0.7232
Tyrosine-protein kinase JAK2 O60674 JAK2_HUMAN Homo sapiens 3 0.7232
CDP-alcohol phosphatidyltransferase AF-2299-like N-terminal domain-containing protein O27985 O27985_ARCFU Archaeoglobus fulgidus 4 0.7229
CDP-alcohol phosphatidyltransferase AF-2299-like N-terminal domain-containing protein O27985 O27985_ARCFU Archaeoglobus fulgidus 4 0.7229
Bromodomain-containing protein 4 O60885 BRD4_HUMAN Homo sapiens 3 0.7227
Bromodomain-containing protein 4 O60885 BRD4_HUMAN Homo sapiens 3 0.7227
Uridine phosphorylase Q5XA29 Q5XA29_STRP6 Streptococcus pyogenes serotype M6 3 0.7222
Uridine phosphorylase Q5XA29 Q5XA29_STRP6 Streptococcus pyogenes serotype M6 3 0.7222
FMN-dependent NAD(P)H:quinone oxidoreductase 1 Q9I5F3 AZOR1_PSEAE Pseudomonas aeruginosa 2 0.7213
FMN-dependent NAD(P)H:quinone oxidoreductase 1 Q9I5F3 AZOR1_PSEAE Pseudomonas aeruginosa 2 0.7213
Flavonoid 3-O-glucosyltransferase A6XNC6 UGFGT_MEDTR Medicago truncatula 3 0.7212
Flavonoid 3-O-glucosyltransferase A6XNC6 UGFGT_MEDTR Medicago truncatula 3 0.7212
Cytidylate kinase B1MB31 B1MB31_MYCA9 Mycobacteroides abscessus 4 0.7206
Cytidylate kinase B1MB31 B1MB31_MYCA9 Mycobacteroides abscessus 4 0.7206
Glycogen synthase kinase-3 beta P49841 GSK3B_HUMAN Homo sapiens 3 0.7205
Glycogen synthase kinase-3 beta P49841 GSK3B_HUMAN Homo sapiens 3 0.7205
APH(2'')-Id O68183 O68183_ENTCA Enterococcus casseliflavus 4 0.7200
APH(2'')-Id O68183 O68183_ENTCA Enterococcus casseliflavus 4 0.7200
Beta-galactoside-specific lectin 4 Q6ITZ3 ML4_VISAL Viscum album 2 0.7181
Beta-galactoside-specific lectin 4 Q6ITZ3 ML4_VISAL Viscum album 2 0.7181
Aminoglycoside N(3)-acetyltransferase A0A3P1UCA6 Q81P86_BACAN Bacillus anthracis 3 0.7163
Aminoglycoside N(3)-acetyltransferase A0A3P1UCA6 Q81P86_BACAN Bacillus anthracis 3 0.7163
Estrogen receptor beta Q92731 ESR2_HUMAN Homo sapiens 3 0.7161
Estrogen receptor beta Q92731 ESR2_HUMAN Homo sapiens 3 0.7161
Mitogen-activated protein kinase 14 Q16539 MK14_HUMAN Homo sapiens 3 0.7158
Mitogen-activated protein kinase 14 Q16539 MK14_HUMAN Homo sapiens 3 0.7158
Beta-secretase 1 P56817 BACE1_HUMAN Homo sapiens 3 0.7151
Beta-secretase 1 P56817 BACE1_HUMAN Homo sapiens 3 0.7151
Chalcone synthase 2 P30074 CHS2_MEDSA Medicago sativa 3 0.7150
Chalcone synthase 2 P30074 CHS2_MEDSA Medicago sativa 3 0.7150
Secoisolariciresinol dehydrogenase Q94KL8 SILD_PODPE Podophyllum peltatum 4 0.7145
Secoisolariciresinol dehydrogenase Q94KL8 SILD_PODPE Podophyllum peltatum 4 0.7145
Fibroblast growth factor receptor 1 P11362 FGFR1_HUMAN Homo sapiens 4 0.7140
Fibroblast growth factor receptor 1 P11362 FGFR1_HUMAN Homo sapiens 4 0.7140
Phytohormone-binding protein CSBP A0A1S3THR8 PHBP_VIGRR Vigna radiata var. radiata 3 0.7139
Phytohormone-binding protein CSBP A0A1S3THR8 PHBP_VIGRR Vigna radiata var. radiata 3 0.7139
Angiotensin-converting enzyme 2 Q9BYF1 ACE2_HUMAN Homo sapiens 2 0.7138
Mitogen-activated protein kinase 14 Q16539 MK14_HUMAN Homo sapiens 4 0.7138
Angiotensin-converting enzyme 2 Q9BYF1 ACE2_HUMAN Homo sapiens 2 0.7138
Casein kinase II subunit alpha P68400 CSK21_HUMAN Homo sapiens 4 0.7138
Mitogen-activated protein kinase 14 Q16539 MK14_HUMAN Homo sapiens 4 0.7138
Casein kinase II subunit alpha P68400 CSK21_HUMAN Homo sapiens 4 0.7138
HTH-type transcriptional repressor PurR P0ACP7 PURR_ECOLI Escherichia coli 3 0.7135
HTH-type transcriptional repressor PurR P0ACP7 PURR_ECOLI Escherichia coli 3 0.7135
Glucan 1,3-beta-glucosidase P29717 EXG1_CANAL Candida albicans 2 0.7132
Glucan 1,3-beta-glucosidase P29717 EXG1_CANAL Candida albicans 2 0.7132
Phosphatidylinositol 5-phosphate 4-kinase type-2 beta P78356 PI42B_HUMAN Homo sapiens 3 0.7127
Phosphatidylinositol 5-phosphate 4-kinase type-2 beta P78356 PI42B_HUMAN Homo sapiens 3 0.7127
Tetracycline repressor protein class D P0ACT4 TETR4_ECOLX Escherichia coli 3 0.7127
Tetracycline repressor protein class D P0ACT4 TETR4_ECOLX Escherichia coli 3 0.7127
Bromodomain-containing protein 4 O60885 BRD4_HUMAN Homo sapiens 3 0.7120
Bromodomain-containing protein 4 O60885 BRD4_HUMAN Homo sapiens 3 0.7120
Carbonic anhydrase 2 P00918 CAH2_HUMAN Homo sapiens 3 0.7119
Carbonic anhydrase 2 P00918 CAH2_HUMAN Homo sapiens 3 0.7119
Tetracycline repressor protein class D P0ACT4 TETR4_ECOLX Escherichia coli 3 0.7098
Tetracycline repressor protein class D P0ACT4 TETR4_ECOLX Escherichia coli 3 0.7098
4,4'-diapophytoene synthase A9JQL9 CRTM_STAAU Staphylococcus aureus 2 0.7093
4,4'-diapophytoene synthase A9JQL9 CRTM_STAAU Staphylococcus aureus 2 0.7093
cGMP-dependent protein kinase 1 Q13976 KGP1_HUMAN Homo sapiens 3 0.7092
cGMP-dependent protein kinase 1 Q13976 KGP1_HUMAN Homo sapiens 3 0.7092
Retinoic acid receptor RXR-alpha P19793 RXRA_HUMAN Homo sapiens 4 0.7090
Retinoic acid receptor RXR-alpha P19793 RXRA_HUMAN Homo sapiens 4 0.7090
Neuropilin-1 O14786 NRP1_HUMAN Homo sapiens 3 0.7076
Neuropilin-1 O14786 NRP1_HUMAN Homo sapiens 3 0.7076
Mitogen-activated protein kinase 14 Q16539 MK14_HUMAN Homo sapiens 3 0.7062
Mitogen-activated protein kinase 14 Q16539 MK14_HUMAN Homo sapiens 3 0.7062
Avidin P02701 AVID_CHICK Gallus gallus 2 0.7056
Avidin P02701 AVID_CHICK Gallus gallus 2 0.7056
Casein kinase II subunit alpha P68400 CSK21_HUMAN Homo sapiens 3 0.7046
Casein kinase II subunit alpha P68400 CSK21_HUMAN Homo sapiens 3 0.7046
Aldo-keto reductase family 1 member C3 P42330 AK1C3_HUMAN Homo sapiens 2 0.7044
Aldo-keto reductase family 1 member C3 P42330 AK1C3_HUMAN Homo sapiens 2 0.7044
Cyclin-dependent kinase 9 P50750 CDK9_HUMAN Homo sapiens 3 0.7043
Cyclin-dependent kinase 9 P50750 CDK9_HUMAN Homo sapiens 3 0.7043
Aurora kinase A O14965 AURKA_HUMAN Homo sapiens 3 0.7036
Aurora kinase A O14965 AURKA_HUMAN Homo sapiens 3 0.7036
Leucoanthocyanidin dioxygenase Q96323 LDOX_ARATH Arabidopsis thaliana 4 0.7032
Leucoanthocyanidin dioxygenase Q96323 LDOX_ARATH Arabidopsis thaliana 4 0.7032
2-phospho-L-lactate transferase Q8PVT6 COFD_METMA Methanosarcina mazei 3 0.7027
2-phospho-L-lactate transferase Q8PVT6 COFD_METMA Methanosarcina mazei 3 0.7027
Acetyl-CoA carboxylase Q00955 ACAC_YEAST Saccharomyces cerevisiae 4 0.7013
Acetyl-CoA carboxylase Q00955 ACAC_YEAST Saccharomyces cerevisiae 4 0.7013
NAD(P) transhydrogenase subunit alpha part 1 Q2RSB2 PNTAA_RHORT Rhodospirillum rubrum 3 0.7008
NAD(P) transhydrogenase subunit alpha part 1 Q2RSB2 PNTAA_RHORT Rhodospirillum rubrum 3 0.7008
Ephrin type-B receptor 4 P54760 EPHB4_HUMAN Homo sapiens 3 0.7003
Ephrin type-B receptor 4 P54760 EPHB4_HUMAN Homo sapiens 3 0.7003

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