Xanthorin - Compound Card

Xanthorin

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Xanthorin

Structure
Zoomed Structure
  • Family: Plantae - Polygonaceae
  • Kingdom: Plantae
  • Class: Quinone
    • Subclass: Anthraquinone
Canonical Smiles COc1cc(O)c2c(c1O)C(=O)c1c(C2=O)c(O)cc(c1)C
InChI InChI=1S/C16H12O6/c1-6-3-7-11(8(17)4-6)16(21)12-9(18)5-10(22-2)15(20)13(12)14(7)19/h3-5,17-18,20H,1-2H3
InChIKey GLLRIXZGBQOFLM-UHFFFAOYSA-N
Formula C16H12O6
HBA 6
HBD 3
MW 300.27
Rotatable Bonds 1
TPSA 104.06
LogP 1.9
Number Rings 3
Number Aromatic Rings 2
Heavy Atom Count 22
Formal Charge 0
Fraction CSP3 0.12
Exact Mass 300.06
Number of Lipinski Rule Violations 0
# Species Family Kingdom NCBI Taxonomy ID
1 Senna sophera Leguminosae/Fabaceae Plantae 948718
2 Rumex abysinicus Polygonaceae Plantae 273505

Showing of synonyms

  • Alemayehu G, Abegaz BM, et al. (1998). A 1,4-anthraquinone-dihydroanthracenone dimer from Senna sophera. Phytochemistry,1998,48(4),699-702. [View] [PubMed]
  • Bizuayehu Z, Ashebir F. (2012). Phytochemical investigation on the root of Rumex abyssinicus (Makmako). M.Sc. Thesis, Addis Ababa University, Ethiopia,2012. [View] [PubMed]
Pubchem: 12444971
Chebi: 144252
Nmrshiftdb2: 60067903

No compound-protein relationship available.

Structure

SMILES: c1cccc(c12)C(=O)c3c(C2=O)cccc3

Level: 0

Mol. Weight: 300.27 g/mol

No bioactivities available.

Absorption

Caco-2 (logPapp)
-4.8
Human Oral Bioavailability 20%
Non-Bioavailable
Human Intestinal Absorption
Absorbed
Madin-Darby Canine Kidney
-4.870
Human Oral Bioavailability 50%
Bioavailable
P-Glycoprotein Inhibitor
Non-Inhibitor
P-Glycoprotein Substrate
Non-Substrate
Skin Permeability
-1.5

Distribution

Blood-Brain Barrier (CNS)
-
Blood-Brain Barrier
Non-Penetrable
Fraction Unbound (Human)
0.940
Plasma Protein Binding
67.11
Steady State Volume of Distribution
-

Metabolism

Breast Cancer Resistance Protein
Inhibitor
CYP 1A2 Inhibitor
Inhibitor
CYP 1A2 Substrate
Substrate
CYP 2C19 Inhibitor
Inhibitor
CYP 2C19 Substrate
Non-Substrate
CYP 2C9 Inhibitor
Inhibitor
CYP 2C9 Substrate
Substrate
CYP 2D6 Inhibitor
Inhibitor
CYP 2D6 Substrate
Non-Substrate
CYP 3A4 Inhibitor
Non-Inhibitor
CYP 3A4 Substrate
Non-Substrate
OATP1B1
Non-Inhibitor
OATP1B3
Non-Inhibitor

Excretion

Clearance
8.880
Organic Cation Transporter 2
Non-Inhibitor
Half-Life of Drug
-

Toxicity

AMES Mutagenesis
Toxic
Avian
Safe
Bee
Toxic
Bioconcentration Factor
1.260
Biodegradation
Safe
Carcinogenesis
Safe
Crustacean
Toxic
Liver Injury I (DILI)
Toxic
Eye Corrosion
Safe
Eye Irritation
Toxic
Maximum Tolerated Dose
1.180
Liver Injury II
Toxic
hERG Blockers
Safe
Daphnia Maga
5.480
Micronucleos
Toxic
NR-AhR
Toxic
NR-AR
Safe
NR-AR-LBD
Safe
NR-Aromatase
Safe
NR-ER
Safe
NR-ER-LBD
Safe
NR-GR
Safe
NR-PPAR-gamma
Safe
NR-TR
Safe
T. Pyriformis
4.140
Rat (Acute)
2.540
Rat (Chronic Oral)
3.370
Fathead Minnow
4.220
Respiratory Disease
Safe
Skin Sensitisation
Safe
SR-ARE
Toxic
SR-ATAD5
Safe
SR-HSE
Safe
SR-MMP
Toxic
SR-p53
Toxic

General Properties

Boiling Point
434.090
Hydration Free Energy
-8.350
Log(D) at pH=7.4
2.680
Log(P)
3.69
Log S
-6.51
Log(Vapor Pressure)
-6.9
Melting Point
213.18
pKa Acid
6.32
pKa Basic
3.73
Protein Name UniProt ID Entry Name Species #Pharmacophore Points Probability (0.7 ≤ Tversky Score ≤ 1.0)
rRNA N-glycosylase D9J2T9 D9J2T9_MOMBA Momordica balsamina 3 0.9496
rRNA N-glycosylase D9J2T9 D9J2T9_MOMBA Momordica balsamina 3 0.9496
Flavin reductase (NADPH) P30043 BLVRB_HUMAN Homo sapiens 3 0.9470
Flavin reductase (NADPH) P30043 BLVRB_HUMAN Homo sapiens 3 0.9470
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A Q9Y233 PDE10_HUMAN Homo sapiens 3 0.9304
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A Q9Y233 PDE10_HUMAN Homo sapiens 3 0.9304
HTH-type transcriptional repressor PurR P0ACP7 PURR_ECOLI Escherichia coli 3 0.9043
HTH-type transcriptional repressor PurR P0ACP7 PURR_ECOLI Escherichia coli 3 0.9043
Epidermal growth factor receptor P00533 EGFR_HUMAN Homo sapiens 3 0.9022
Epidermal growth factor receptor P00533 EGFR_HUMAN Homo sapiens 3 0.9022
Epidermal growth factor receptor P00533 EGFR_HUMAN Homo sapiens 3 0.8964
Epidermal growth factor receptor P00533 EGFR_HUMAN Homo sapiens 3 0.8964
Riboflavin synthase P0AFU8 RISA_ECOLI Escherichia coli 4 0.8925
Riboflavin synthase P0AFU8 RISA_ECOLI Escherichia coli 4 0.8925
HTH-type transcriptional repressor PurR P0ACP7 PURR_ECOLI Escherichia coli 3 0.8902
HTH-type transcriptional repressor PurR P0ACP7 PURR_ECOLI Escherichia coli 3 0.8902
HTH-type transcriptional repressor PurR P0ACP7 PURR_ECOLI Escherichia coli 3 0.8703
HTH-type transcriptional repressor PurR P0ACP7 PURR_ECOLI Escherichia coli 3 0.8703
E3 ubiquitin-protein ligase Mdm2 P56273 MDM2_XENLA Xenopus laevis 3 0.8655
E3 ubiquitin-protein ligase Mdm2 P56273 MDM2_XENLA Xenopus laevis 3 0.8655
Fibroblast growth factor receptor 1 P11362 FGFR1_HUMAN Homo sapiens 3 0.8569
Fibroblast growth factor receptor 1 P11362 FGFR1_HUMAN Homo sapiens 3 0.8569
HTH-type transcriptional repressor PurR P0ACP7 PURR_ECOLI Escherichia coli 3 0.8565
HTH-type transcriptional repressor PurR P0ACP7 PURR_ECOLI Escherichia coli 3 0.8565
Tyrosine-protein kinase JAK2 O60674 JAK2_HUMAN Homo sapiens 3 0.8532
Tyrosine-protein kinase JAK2 O60674 JAK2_HUMAN Homo sapiens 3 0.8532
Carbonic anhydrase 2 P00918 CAH2_HUMAN Homo sapiens 3 0.8516
Carbonic anhydrase 2 P00918 CAH2_HUMAN Homo sapiens 3 0.8516
HTH-type transcriptional repressor PurR P0ACP7 PURR_ECOLI Escherichia coli 3 0.8515
HTH-type transcriptional repressor PurR P0ACP7 PURR_ECOLI Escherichia coli 3 0.8515
Glycogen synthase kinase-3 beta P49841 GSK3B_HUMAN Homo sapiens 3 0.8495
Glycogen synthase kinase-3 beta P49841 GSK3B_HUMAN Homo sapiens 3 0.8495
3',5'-cyclic-AMP phosphodiesterase 4D Q08499 PDE4D_HUMAN Homo sapiens 3 0.8490
3',5'-cyclic-AMP phosphodiesterase 4D Q08499 PDE4D_HUMAN Homo sapiens 3 0.8490
Cell division cycle 7-related protein kinase O00311 CDC7_HUMAN Homo sapiens 4 0.8397
Cell division cycle 7-related protein kinase O00311 CDC7_HUMAN Homo sapiens 4 0.8397
Putative ketoacyl reductase P16544 ACT3_STRCO Streptomyces coelicolor / M145) 3 0.8395
Putative ketoacyl reductase P16544 ACT3_STRCO Streptomyces coelicolor / M145) 3 0.8395
3',5'-cyclic-AMP phosphodiesterase 4D Q08499 PDE4D_HUMAN Homo sapiens 3 0.8335
3',5'-cyclic-AMP phosphodiesterase 4D Q08499 PDE4D_HUMAN Homo sapiens 3 0.8335
HTH-type transcriptional repressor PurR P0ACP7 PURR_ECOLI Escherichia coli 3 0.8333
HTH-type transcriptional repressor PurR P0ACP7 PURR_ECOLI Escherichia coli 3 0.8333
Ribosomal small subunit pseudouridine synthase A P0AA43 RSUA_ECOLI Escherichia coli 3 0.8314
Ribosomal small subunit pseudouridine synthase A P0AA43 RSUA_ECOLI Escherichia coli 3 0.8314
Basic phospholipase A2 VRV-PL-VIIIa P59071 PA2B8_DABRR Daboia russelii 3 0.8308
Basic phospholipase A2 VRV-PL-VIIIa P59071 PA2B8_DABRR Daboia russelii 3 0.8308
Nitric oxide synthase 1 P29476 NOS1_RAT Rattus norvegicus 5 0.8284
Nitric oxide synthase 1 P29476 NOS1_RAT Rattus norvegicus 5 0.8284
Serine/threonine-protein kinase Chk1 O14757 CHK1_HUMAN Homo sapiens 3 0.8270
Serine/threonine-protein kinase Chk1 O14757 CHK1_HUMAN Homo sapiens 3 0.8270
Protein mono-ADP-ribosyltransferase PARP3 Q9Y6F1 PARP3_HUMAN Homo sapiens 3 0.8212
Protein mono-ADP-ribosyltransferase PARP3 Q9Y6F1 PARP3_HUMAN Homo sapiens 3 0.8212
Heat shock protein HSP 90-alpha P07900 HS90A_HUMAN Homo sapiens 3 0.8143
Heat shock protein HSP 90-alpha P07900 HS90A_HUMAN Homo sapiens 3 0.8143
Sulfotransferase 1E1 P49888 ST1E1_HUMAN Homo sapiens 3 0.8130
Sulfotransferase 1E1 P49888 ST1E1_HUMAN Homo sapiens 3 0.8130
ActVA 6 protein Q53908 Q53908_STRCH Streptomyces coelicolor 4 0.8102
ActVA 6 protein Q53908 Q53908_STRCH Streptomyces coelicolor 4 0.8102
E3 ubiquitin-protein ligase Mdm2 Q00987 MDM2_HUMAN Homo sapiens 3 0.8094
E3 ubiquitin-protein ligase Mdm2 Q00987 MDM2_HUMAN Homo sapiens 3 0.8094
Alpha-ketoglutarate-dependent dioxygenase FTO Q9C0B1 FTO_HUMAN Homo sapiens 3 0.8076
Alpha-ketoglutarate-dependent dioxygenase FTO Q9C0B1 FTO_HUMAN Homo sapiens 3 0.8076
HTH-type transcriptional repressor PurR P0ACP7 PURR_ECOLI Escherichia coli 3 0.8045
HTH-type transcriptional repressor PurR P0ACP7 PURR_ECOLI Escherichia coli 3 0.8045
Nitric oxide synthase oxygenase O34453 NOSO_BACSU Bacillus subtilis 4 0.8027
Nitric oxide synthase oxygenase O34453 NOSO_BACSU Bacillus subtilis 4 0.8027
Serine/threonine-protein kinase PLK1 P53350 PLK1_HUMAN Homo sapiens 4 0.8026
Serine/threonine-protein kinase PLK1 P53350 PLK1_HUMAN Homo sapiens 4 0.8026
Nuclear receptor subfamily 4immunitygroup A member 1 P22736 NR4A1_HUMAN Homo sapiens 3 0.7977
Nuclear receptor subfamily 4immunitygroup A member 1 P22736 NR4A1_HUMAN Homo sapiens 3 0.7977
Toxoflavin degrading enzyme E3SET7 E3SET7_PAEPO Paenibacillus polymyxa 3 0.7906
Toxoflavin degrading enzyme E3SET7 E3SET7_PAEPO Paenibacillus polymyxa 3 0.7906
Prostaglandin E synthase 2 Q9N0A4 PGES2_MACFA Macaca fascicularis 3 0.7852
Prostaglandin E synthase 2 Q9N0A4 PGES2_MACFA Macaca fascicularis 3 0.7852
Ribonuclease J H9CZL7 H9CZL7_DEIRD Deinococcus radiodurans 3 0.7801
Ribonuclease J H9CZL7 H9CZL7_DEIRD Deinococcus radiodurans 3 0.7801
Protein ppBat Q8A8A4 Q8A8A4_BACTN Bacteroides thetaiotaomicron VPI-5482 3 0.7785
Protein ppBat Q8A8A4 Q8A8A4_BACTN Bacteroides thetaiotaomicron VPI-5482 3 0.7785
beta-glucosidase Q92AS9 Q92AS9_LISIN Listeria innocua serovar 6a 3 0.7761
beta-glucosidase Q92AS9 Q92AS9_LISIN Listeria innocua serovar 6a 3 0.7761
Vascular endothelial growth factor receptor 2 P35968 VGFR2_HUMAN Homo sapiens 3 0.7753
Vascular endothelial growth factor receptor 2 P35968 VGFR2_HUMAN Homo sapiens 3 0.7753
Ribosyldihydronicotinamide dehydrogenase [quinone] P16083 NQO2_HUMAN Homo sapiens 3 0.7750
Ribosyldihydronicotinamide dehydrogenase [quinone] P16083 NQO2_HUMAN Homo sapiens 3 0.7750
Casein kinase II subunit alpha P28523 CSK2A_MAIZE Zea mays 4 0.7723
Casein kinase II subunit alpha P28523 CSK2A_MAIZE Zea mays 4 0.7723
Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase F6MZ55 F6MZ55_9FIRM Sporomusa ovata 3 0.7706
Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase F6MZ55 F6MZ55_9FIRM Sporomusa ovata 3 0.7706
Casein kinase II subunit alpha P28523 CSK2A_MAIZE Zea mays 4 0.7659
Casein kinase II subunit alpha P28523 CSK2A_MAIZE Zea mays 4 0.7659
Casein kinase II subunit alpha P28523 CSK2A_MAIZE Zea mays 4 0.7655
Casein kinase II subunit alpha P28523 CSK2A_MAIZE Zea mays 4 0.7655
Transcriptional regulator, PadR-like family A2RI36 A2RI36_LACLM Lactococcus lactis subsp. cremoris 2 0.7641
Transcriptional regulator, PadR-like family A2RI36 A2RI36_LACLM Lactococcus lactis subsp. cremoris 2 0.7641
MAP kinase-activated protein kinase 2 P49137 MAPK2_HUMAN Homo sapiens 3 0.7637
MAP kinase-activated protein kinase 2 P49137 MAPK2_HUMAN Homo sapiens 3 0.7637
Epidermal growth factor receptor P00533 EGFR_HUMAN Homo sapiens 3 0.7635
Epidermal growth factor receptor P00533 EGFR_HUMAN Homo sapiens 3 0.7635
Methionine aminopeptidase 2 P50579 MAP2_HUMAN Homo sapiens 3 0.7623
Methionine aminopeptidase 2 P50579 MAP2_HUMAN Homo sapiens 3 0.7623
NAD(P)H-hydrate epimerase Q8K4Z3 NNRE_MOUSE Mus musculus 3 0.7587
NAD(P)H-hydrate epimerase Q8K4Z3 NNRE_MOUSE Mus musculus 3 0.7587
Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplastic Q43088 RBCMT_PEA Pisum sativum 3 0.7484
Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplastic Q43088 RBCMT_PEA Pisum sativum 3 0.7484
Polyprotein Q80J95 Q80J95_9CALI Murine norovirus 1 3 0.7470
Polyprotein Q80J95 Q80J95_9CALI Murine norovirus 1 3 0.7470
Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplastic Q43088 RBCMT_PEA Pisum sativum 3 0.7461
Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplastic Q43088 RBCMT_PEA Pisum sativum 3 0.7461
Tyrosine-protein kinase Lck P06239 LCK_HUMAN Homo sapiens 3 0.7456
Tyrosine-protein kinase Lck P06239 LCK_HUMAN Homo sapiens 3 0.7456
APH(2'')-Id O68183 O68183_ENTCA Enterococcus casseliflavus 4 0.7453
APH(2'')-Id O68183 O68183_ENTCA Enterococcus casseliflavus 4 0.7453
Cyclin-dependent kinase 9 P50750 CDK9_HUMAN Homo sapiens 3 0.7445
Cyclin-dependent kinase 9 P50750 CDK9_HUMAN Homo sapiens 3 0.7445
Catechol O-methyltransferase P22734 COMT_RAT Rattus norvegicus 3 0.7443
Aklavinone 12-hydroxylase RdmE Q54530 DNRF_STREF Streptomyces purpurascens 4 0.7443
Aklavinone 12-hydroxylase RdmE Q54530 DNRF_STREF Streptomyces purpurascens 4 0.7443
Catechol O-methyltransferase P22734 COMT_RAT Rattus norvegicus 3 0.7443
Mitogen-activated protein kinase 1 P28482 MK01_HUMAN Homo sapiens 3 0.7428
Mitogen-activated protein kinase 1 P28482 MK01_HUMAN Homo sapiens 3 0.7428
Nitric oxide synthase 1 P29476 NOS1_RAT Rattus norvegicus 5 0.7422
Nitric oxide synthase 1 P29476 NOS1_RAT Rattus norvegicus 5 0.7422
Orotidine 5'-phosphate decarboxylase O58462 PYRF_PYRHO Pyrococcus horikoshii 3 0.7397
Orotidine 5'-phosphate decarboxylase O58462 PYRF_PYRHO Pyrococcus horikoshii 3 0.7397
Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplastic Q43088 RBCMT_PEA Pisum sativum 3 0.7386
Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplastic Q43088 RBCMT_PEA Pisum sativum 3 0.7386
Glycogen synthase kinase-3 beta P49841 GSK3B_HUMAN Homo sapiens 3 0.7378
Glycogen synthase kinase-3 beta P49841 GSK3B_HUMAN Homo sapiens 3 0.7378
Glucan 1,3-beta-glucosidase P29717 EXG1_CANAL Candida albicans 2 0.7370
Glucan 1,3-beta-glucosidase P29717 EXG1_CANAL Candida albicans 2 0.7370
3-phosphoinositide-dependent protein kinase 1 O15530 PDPK1_HUMAN Homo sapiens 4 0.7366
3-phosphoinositide-dependent protein kinase 1 O15530 PDPK1_HUMAN Homo sapiens 4 0.7366
HTH-type transcriptional repressor PurR P0ACP7 PURR_ECOLI Escherichia coli 3 0.7353
HTH-type transcriptional repressor PurR P0ACP7 PURR_ECOLI Escherichia coli 3 0.7353
Carbonic anhydrase 2 P00918 CAH2_HUMAN Homo sapiens 2 0.7338
Carbonic anhydrase 2 P00918 CAH2_HUMAN Homo sapiens 2 0.7338
Thymidylate synthase P00469 TYSY_LACCA Lacticaseibacillus casei 4 0.7332
Thymidylate synthase P00469 TYSY_LACCA Lacticaseibacillus casei 4 0.7332
4-hydroxyphenylacetate 3-monooxygenase Q8YHT7 Q8YHT7_BRUME Brucella melitensis biotype 1 2 0.7330
4-hydroxyphenylacetate 3-monooxygenase Q8YHT7 Q8YHT7_BRUME Brucella melitensis biotype 1 2 0.7330
Tyrosine-protein kinase Lyn P25911 LYN_MOUSE Mus musculus 4 0.7317
Tyrosine-protein kinase Lyn P25911 LYN_MOUSE Mus musculus 4 0.7317
Basic phospholipase A2 VRV-PL-VIIIa P59071 PA2B8_DABRR Daboia russelii 4 0.7308
Basic phospholipase A2 VRV-PL-VIIIa P59071 PA2B8_DABRR Daboia russelii 4 0.7308
Fructose-1,6-bisphosphatase 1 P00636 F16P1_PIG Sus scrofa 3 0.7264
Fructose-1,6-bisphosphatase 1 P00636 F16P1_PIG Sus scrofa 3 0.7264
Histone-lysine N-methyltransferase SETD7 Q8WTS6 SETD7_HUMAN Homo sapiens 3 0.7224
Histone-lysine N-methyltransferase SETD7 Q8WTS6 SETD7_HUMAN Homo sapiens 3 0.7224
Aldo-keto reductase family 1 member C3 P42330 AK1C3_HUMAN Homo sapiens 3 0.7207
Aldo-keto reductase family 1 member C3 P42330 AK1C3_HUMAN Homo sapiens 3 0.7207
Tubulin alpha-1B chain P81947 TBA1B_BOVIN Bos taurus 3 0.7180
Tubulin alpha-1B chain P81947 TBA1B_BOVIN Bos taurus 3 0.7180
Enoyl-[acyl-carrier-protein] reductase [NADH] P9WGR1 INHA_MYCTU Mycobacterium tuberculosis 3 0.7171
Enoyl-[acyl-carrier-protein] reductase [NADH] P9WGR1 INHA_MYCTU Mycobacterium tuberculosis 3 0.7171
APH(2'')-Id O68183 O68183_ENTCA Enterococcus casseliflavus 3 0.7156
APH(2'')-Id O68183 O68183_ENTCA Enterococcus casseliflavus 3 0.7156
Deoxycytidine kinase P27707 DCK_HUMAN Homo sapiens 4 0.7151
Deoxycytidine kinase P27707 DCK_HUMAN Homo sapiens 4 0.7151
GCN5-related N-acetyltransferase B1YEL6 B1YEL6_EXIS2 Exiguobacterium sibiricum 3 0.7121
GCN5-related N-acetyltransferase B1YEL6 B1YEL6_EXIS2 Exiguobacterium sibiricum 3 0.7121
Cyclin-dependent kinase 2 P24941 CDK2_HUMAN Homo sapiens 3 0.7120
Cyclin-dependent kinase 2 P24941 CDK2_HUMAN Homo sapiens 3 0.7120
Cyclin-dependent kinase 2 P24941 CDK2_HUMAN Homo sapiens 3 0.7118
Cyclin-dependent kinase 2 P24941 CDK2_HUMAN Homo sapiens 3 0.7118
Serine/threonine-protein kinase pim-1 P11309 PIM1_HUMAN Homo sapiens 3 0.7112
Serine/threonine-protein kinase pim-1 P11309 PIM1_HUMAN Homo sapiens 3 0.7112
Casein kinase II subunit alpha P28523 CSK2A_MAIZE Zea mays 4 0.7101
Casein kinase II subunit alpha P28523 CSK2A_MAIZE Zea mays 4 0.7101
Methionine aminopeptidase 2 P50579 MAP2_HUMAN Homo sapiens 3 0.7100
Methionine aminopeptidase 2 P50579 MAP2_HUMAN Homo sapiens 3 0.7100
Casein kinase II subunit alpha P68400 CSK21_HUMAN Homo sapiens 2 0.7085
Casein kinase II subunit alpha P68400 CSK21_HUMAN Homo sapiens 2 0.7085
E3 ubiquitin-protein ligase Mdm2 Q00987 MDM2_HUMAN Homo sapiens 3 0.7083
E3 ubiquitin-protein ligase Mdm2 Q00987 MDM2_HUMAN Homo sapiens 3 0.7083
Cyclin-dependent kinase 2 P24941 CDK2_HUMAN Homo sapiens 3 0.7081
Cyclin-dependent kinase 2 P24941 CDK2_HUMAN Homo sapiens 3 0.7081
GCN5-related N-acetyltransferase B1YEL6 B1YEL6_EXIS2 Exiguobacterium sibiricum 3 0.7070
GCN5-related N-acetyltransferase B1YEL6 B1YEL6_EXIS2 Exiguobacterium sibiricum 3 0.7070
Tubulin alpha chain D0VWZ0 D0VWZ0_SHEEP Ovis aries 3 0.7063
Tubulin alpha chain D0VWZ0 D0VWZ0_SHEEP Ovis aries 3 0.7063
dTDP-4-dehydrorhamnose 3,5-epimerase A0A6L7H6N0 A0A1S0QLH9_BACAN Bacillus anthracis 3 0.7046
dTDP-4-dehydrorhamnose 3,5-epimerase A0A6L7H6N0 A0A1S0QLH9_BACAN Bacillus anthracis 3 0.7046
Ribosomal small subunit pseudouridine synthase A P0AA43 RSUA_ECOLI Escherichia coli 4 0.7040
Ribosomal small subunit pseudouridine synthase A P0AA43 RSUA_ECOLI Escherichia coli 4 0.7040
Pteridine reductase 1 Q01782 PTR1_LEIMA Leishmania major 3 0.7025
Beta-secretase 1 P56817 BACE1_HUMAN Homo sapiens 3 0.7025
Beta-secretase 1 P56817 BACE1_HUMAN Homo sapiens 3 0.7025
Pteridine reductase 1 Q01782 PTR1_LEIMA Leishmania major 3 0.7025
Tetracycline repressor protein class H P51561 TETR8_PASMD Pasteurella multocida 3 0.7010
D-mycarose 3-C-methyltransferase Q194Q4 Q194Q4_STRAA Streptomyces argillaceus 4 0.7010
D-mycarose 3-C-methyltransferase Q194Q4 Q194Q4_STRAA Streptomyces argillaceus 4 0.7010
Tetracycline repressor protein class H P51561 TETR8_PASMD Pasteurella multocida 3 0.7010

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