3'-O-methylpratensein - Compound Card

3'-O-methylpratensein

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3'-O-methylpratensein

Structure
Zoomed Structure
  • Family: Plantae - Leguminosae/Fabaceae
  • Kingdom: Plantae
  • Class: Flavonoid
Canonical Smiles COc1cc(ccc1OC)c1coc2c(c1=O)c(O)cc(c2)O
InChI InChI=1S/C17H14O6/c1-21-13-4-3-9(5-14(13)22-2)11-8-23-15-7-10(18)6-12(19)16(15)17(11)20/h3-8,18-19H,1-2H3
InChIKey KRJPWSDKKBLTLE-UHFFFAOYSA-N
Formula C17H14O6
HBA 6
HBD 2
MW 314.29
Rotatable Bonds 3
TPSA 89.13
LogP 2.89
Number Rings 3
Number Aromatic Rings 3
Heavy Atom Count 23
Formal Charge 0
Fraction CSP3 0.12
Exact Mass 314.08
Number of Lipinski Rule Violations 0
# Species Family Kingdom NCBI Taxonomy ID
1 Erythrina schliebenii Leguminosae/Fabaceae Plantae 2590720

Showing of synonyms

  • Nyandoro SS, Munissi JJ, et al. (2017). Flavonoids from Erythrina schliebenii.. Journal of Natural Products,2017,80(2),377-383. [View] [PubMed]
Pubchem: 5408543
Nmrshiftdb2: 70010903

No compound-protein relationship available.

Structure

SMILES: c1cccc(c12)occ(c2=O)-c3ccccc3

Level: 1

Mol. Weight: 314.29 g/mol

Structure

SMILES: c1cccc(c12)occc2=O

Level: 0

Mol. Weight: 314.29 g/mol

Structure

SMILES: c1ccccc1

Level: 0

Mol. Weight: 314.29 g/mol

No bioactivities available.

Absorption

Caco-2 (logPapp)
-4.65
Human Oral Bioavailability 20%
Bioavailable
Human Intestinal Absorption
Absorbed
Madin-Darby Canine Kidney
-4.810
Human Oral Bioavailability 50%
Bioavailable
P-Glycoprotein Inhibitor
Inhibitor
P-Glycoprotein Substrate
Non-Substrate
Skin Permeability
-1.01

Distribution

Blood-Brain Barrier (CNS)
-
Blood-Brain Barrier
Penetrable
Fraction Unbound (Human)
1.270
Plasma Protein Binding
83.95
Steady State Volume of Distribution
-

Metabolism

Breast Cancer Resistance Protein
Inhibitor
CYP 1A2 Inhibitor
Inhibitor
CYP 1A2 Substrate
Substrate
CYP 2C19 Inhibitor
Inhibitor
CYP 2C19 Substrate
Non-Substrate
CYP 2C9 Inhibitor
Non-Inhibitor
CYP 2C9 Substrate
Substrate
CYP 2D6 Inhibitor
Inhibitor
CYP 2D6 Substrate
Non-Substrate
CYP 3A4 Inhibitor
Inhibitor
CYP 3A4 Substrate
Non-Substrate
OATP1B1
Non-Inhibitor
OATP1B3
Non-Inhibitor

Excretion

Clearance
5.720
Organic Cation Transporter 2
Non-Inhibitor
Half-Life of Drug
-

Toxicity

AMES Mutagenesis
Safe
Avian
Safe
Bee
Toxic
Bioconcentration Factor
1.890
Biodegradation
Safe
Carcinogenesis
Safe
Crustacean
Toxic
Liver Injury I (DILI)
Toxic
Eye Corrosion
Safe
Eye Irritation
Toxic
Maximum Tolerated Dose
1.420
Liver Injury II
Toxic
hERG Blockers
Safe
Daphnia Maga
5.450
Micronucleos
Toxic
NR-AhR
Toxic
NR-AR
Safe
NR-AR-LBD
Safe
NR-Aromatase
Safe
NR-ER
Safe
NR-ER-LBD
Toxic
NR-GR
Toxic
NR-PPAR-gamma
Safe
NR-TR
Toxic
T. Pyriformis
3.200
Rat (Acute)
2.100
Rat (Chronic Oral)
2.570
Fathead Minnow
4.810
Respiratory Disease
Toxic
Skin Sensitisation
Safe
SR-ARE
Toxic
SR-ATAD5
Toxic
SR-HSE
Safe
SR-MMP
Toxic
SR-p53
Toxic

General Properties

Boiling Point
451.780
Hydration Free Energy
-11.660
Log(D) at pH=7.4
2.890
Log(P)
3.17
Log S
-5.52
Log(Vapor Pressure)
-7.84
Melting Point
216.04
pKa Acid
7.65
pKa Basic
4.03
Protein Name UniProt ID Entry Name Species #Pharmacophore Points Probability (0.7 ≤ Tversky Score ≤ 1.0)
IOMT 3 Q06YR3 Q06YR3_MEDTR Medicago truncatula 4 0.9528
IOMT 3 Q06YR3 Q06YR3_MEDTR Medicago truncatula 4 0.9528
Bromodomain adjacent to zinc finger domain protein 2B Q9UIF8 BAZ2B_HUMAN Homo sapiens 3 0.9513
Bromodomain adjacent to zinc finger domain protein 2B Q9UIF8 BAZ2B_HUMAN Homo sapiens 3 0.9513
Serine/threonine-protein kinase 24 Q9Y6E0 STK24_HUMAN Homo sapiens 3 0.9481
Serine/threonine-protein kinase 24 Q9Y6E0 STK24_HUMAN Homo sapiens 3 0.9481
Heat shock protein HSP 90-alpha P07900 HS90A_HUMAN Homo sapiens 3 0.9448
Heat shock protein HSP 90-alpha P07900 HS90A_HUMAN Homo sapiens 3 0.9448
Chitinase A Q9AMP1 Q9AMP1_VIBHA Vibrio harveyi 3 0.9410
Chitinase A Q9AMP1 Q9AMP1_VIBHA Vibrio harveyi 3 0.9410
Serine/threonine-protein kinase 10 O94804 STK10_HUMAN Homo sapiens 3 0.9404
Serine/threonine-protein kinase 10 O94804 STK10_HUMAN Homo sapiens 3 0.9404
Estrogen receptor P03372 ESR1_HUMAN Homo sapiens 4 0.9404
Estrogen receptor P03372 ESR1_HUMAN Homo sapiens 4 0.9404
3',5'-cyclic-AMP phosphodiesterase 4D Q08499 PDE4D_HUMAN Homo sapiens 3 0.9386
3',5'-cyclic-AMP phosphodiesterase 4D Q08499 PDE4D_HUMAN Homo sapiens 3 0.9386
HTH-type transcriptional regulator TtgR Q9AIU0 TTGR_PSEPT Pseudomonas putida 3 0.9306
HTH-type transcriptional regulator TtgR Q9AIU0 TTGR_PSEPT Pseudomonas putida 3 0.9306
Thymidylate synthase P00469 TYSY_LACCA Lacticaseibacillus casei 3 0.9301
Thymidylate synthase P00469 TYSY_LACCA Lacticaseibacillus casei 3 0.9301
NAD-capped RNA hydrolase NudC P32664 NUDC_ECOLI Escherichia coli 3 0.9295
NAD-capped RNA hydrolase NudC P32664 NUDC_ECOLI Escherichia coli 3 0.9295
Biflaviolin synthase CYP158A1 Q9KZF5 C1581_STRCO Streptomyces coelicolor / M145) 3 0.9278
Biflaviolin synthase CYP158A1 Q9KZF5 C1581_STRCO Streptomyces coelicolor / M145) 3 0.9278
Estrogen receptor P03372 ESR1_HUMAN Homo sapiens 4 0.9258
Estrogen receptor P03372 ESR1_HUMAN Homo sapiens 4 0.9258
Aldo-keto reductase family 1 member B1 P15121 ALDR_HUMAN Homo sapiens 3 0.9237
Aldo-keto reductase family 1 member B1 P15121 ALDR_HUMAN Homo sapiens 3 0.9237
Toxoflavin degrading enzyme E3SET7 E3SET7_PAEPO Paenibacillus polymyxa 3 0.9189
Toxoflavin degrading enzyme E3SET7 E3SET7_PAEPO Paenibacillus polymyxa 3 0.9189
Transthyretin P02766 TTHY_HUMAN Homo sapiens 4 0.9168
Transthyretin P02766 TTHY_HUMAN Homo sapiens 4 0.9168
Dihydrofolate reductase P22906 DYR_CANAX Candida albicans 4 0.9140
Dihydrofolate reductase P22906 DYR_CANAX Candida albicans 4 0.9140
17beta-hydroxysteroid dehydrogenase O93874 O93874_COCLU Cochliobolus lunatus 4 0.9119
17beta-hydroxysteroid dehydrogenase O93874 O93874_COCLU Cochliobolus lunatus 4 0.9119
Epidermal growth factor receptor P00533 EGFR_HUMAN Homo sapiens 3 0.9102
Epidermal growth factor receptor P00533 EGFR_HUMAN Homo sapiens 3 0.9102
Nitric oxide synthase oxygenase O34453 NOSO_BACSU Bacillus subtilis 4 0.9060
Nitric oxide synthase oxygenase O34453 NOSO_BACSU Bacillus subtilis 4 0.9060
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A Q9Y233 PDE10_HUMAN Homo sapiens 3 0.9041
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A Q9Y233 PDE10_HUMAN Homo sapiens 3 0.9041
Basic phospholipase A2 VRV-PL-VIIIa P59071 PA2B8_DABRR Daboia russelii 3 0.9039
Basic phospholipase A2 VRV-PL-VIIIa P59071 PA2B8_DABRR Daboia russelii 3 0.9039
Epidermal growth factor receptor P00533 EGFR_HUMAN Homo sapiens 3 0.8972
Epidermal growth factor receptor P00533 EGFR_HUMAN Homo sapiens 3 0.8972
Steroid C26-monooxygenase P9WPP1 CP125_MYCTU Mycobacterium tuberculosis 3 0.8851
Steroid C26-monooxygenase P9WPP1 CP125_MYCTU Mycobacterium tuberculosis 3 0.8851
High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A O76083 PDE9A_HUMAN Homo sapiens 3 0.8824
High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A O76083 PDE9A_HUMAN Homo sapiens 3 0.8824
Bromodomain-containing protein 2 P25440 BRD2_HUMAN Homo sapiens 3 0.8813
Bromodomain-containing protein 2 P25440 BRD2_HUMAN Homo sapiens 3 0.8813
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase Q8DNV6 Q8DNV6_STRR6 Streptococcus pneumoniae 3 0.8776
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase Q8DNV6 Q8DNV6_STRR6 Streptococcus pneumoniae 3 0.8776
Cytochrome P450 1A1 P04798 CP1A1_HUMAN Homo sapiens 3 0.8775
Cytochrome P450 1A1 P04798 CP1A1_HUMAN Homo sapiens 3 0.8775
Biflaviolin synthase CYP158A2 Q9FCA6 C1582_STRCO Streptomyces coelicolor / M145) 3 0.8757
Biflaviolin synthase CYP158A2 Q9FCA6 C1582_STRCO Streptomyces coelicolor / M145) 3 0.8757
Steroid Delta-isomerase P00947 SDIS_COMTE Comamonas testosteroni 3 0.8749
Steroid Delta-isomerase P00947 SDIS_COMTE Comamonas testosteroni 3 0.8749
Steroid Delta-isomerase P00947 SDIS_COMTE Comamonas testosteroni 3 0.8734
Steroid Delta-isomerase P00947 SDIS_COMTE Comamonas testosteroni 3 0.8734
Histone deacetylase 4 P56524 HDAC4_HUMAN Homo sapiens 3 0.8701
Histone deacetylase 4 P56524 HDAC4_HUMAN Homo sapiens 3 0.8701
Bromodomain-containing protein 4 O60885 BRD4_HUMAN Homo sapiens 4 0.8684
Bromodomain-containing protein 4 O60885 BRD4_HUMAN Homo sapiens 4 0.8684
Casein kinase II subunit alpha P68400 CSK21_HUMAN Homo sapiens 5 0.8680
Casein kinase II subunit alpha P68400 CSK21_HUMAN Homo sapiens 5 0.8680
Tetracycline repressor protein class D P0ACT4 TETR4_ECOLX Escherichia coli 3 0.8666
Tetracycline repressor protein class D P0ACT4 TETR4_ECOLX Escherichia coli 3 0.8666
Bromodomain-containing protein 4 O60885 BRD4_HUMAN Homo sapiens 4 0.8639
Bromodomain-containing protein 4 O60885 BRD4_HUMAN Homo sapiens 4 0.8639
Succinate dehydrogenase flavoprotein subunit P0AC41 SDHA_ECOLI Escherichia coli 3 0.8634
Succinate dehydrogenase flavoprotein subunit P0AC41 SDHA_ECOLI Escherichia coli 3 0.8634
Biflaviolin synthase CYP158A2 Q9FCA6 C1582_STRCO Streptomyces coelicolor / M145) 3 0.8630
Biflaviolin synthase CYP158A2 Q9FCA6 C1582_STRCO Streptomyces coelicolor / M145) 3 0.8630
Pteridine reductase, putative Q581W1 Q581W1_TRYB2 Trypanosoma brucei brucei 4 0.8613
Pteridine reductase, putative Q581W1 Q581W1_TRYB2 Trypanosoma brucei brucei 4 0.8613
Cyclin-dependent kinase 2 P24941 CDK2_HUMAN Homo sapiens 3 0.8610
Cyclin-dependent kinase 2 P24941 CDK2_HUMAN Homo sapiens 3 0.8610
Heat shock protein HSP 90-alpha P07900 HS90A_HUMAN Homo sapiens 3 0.8574
Heat shock protein HSP 90-alpha P07900 HS90A_HUMAN Homo sapiens 3 0.8574
Transthyretin P02767 TTHY_RAT Rattus norvegicus 3 0.8565
Transthyretin P02767 TTHY_RAT Rattus norvegicus 3 0.8565
Nodulin-13 P93330 NOD13_MEDTR Medicago truncatula 3 0.8551
Nodulin-13 P93330 NOD13_MEDTR Medicago truncatula 3 0.8551
Biotin carboxylase P24182 ACCC_ECOLI Escherichia coli 4 0.8510
Biotin carboxylase P24182 ACCC_ECOLI Escherichia coli 4 0.8510
Tyrosine-protein kinase Lck P06239 LCK_HUMAN Homo sapiens 4 0.8506
Tyrosine-protein kinase Lck P06239 LCK_HUMAN Homo sapiens 4 0.8506
ATP-dependent molecular chaperone HSP82 P02829 HSP82_YEAST Saccharomyces cerevisiae 3 0.8496
ATP-dependent molecular chaperone HSP82 P02829 HSP82_YEAST Saccharomyces cerevisiae 3 0.8496
Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase Q9TQS6 DHDH_MACFA Macaca fascicularis 3 0.8488
Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase Q9TQS6 DHDH_MACFA Macaca fascicularis 3 0.8488
Phytohormone-binding protein CSBP A0A1S3THR8 PHBP_VIGRR Vigna radiata var. radiata 3 0.8485
Phytohormone-binding protein CSBP A0A1S3THR8 PHBP_VIGRR Vigna radiata var. radiata 3 0.8485
Mycocyclosin synthase P9WPP7 CP121_MYCTU Mycobacterium tuberculosis 3 0.8420
Mycocyclosin synthase P9WPP7 CP121_MYCTU Mycobacterium tuberculosis 3 0.8420
Sulfide-quinone reductase B7JBP8 SQRD_ACIF2 Acidithiobacillus ferrooxidans) 3 0.8401
Sulfide-quinone reductase B7JBP8 SQRD_ACIF2 Acidithiobacillus ferrooxidans) 3 0.8401
Fibroblast growth factor receptor 1 P11362 FGFR1_HUMAN Homo sapiens 3 0.8383
Fibroblast growth factor receptor 1 P11362 FGFR1_HUMAN Homo sapiens 3 0.8383
Chalcone--flavanone isomerase 1 P28012 CFI1_MEDSA Medicago sativa 3 0.8369
Chalcone--flavanone isomerase 1 P28012 CFI1_MEDSA Medicago sativa 3 0.8369
Casein kinase II subunit alpha P68400 CSK21_HUMAN Homo sapiens 3 0.8349
Casein kinase II subunit alpha P68400 CSK21_HUMAN Homo sapiens 3 0.8349
Gag-Pol polyprotein P12497 POL_HV1N5 Human immunodeficiency virus type 1 group M subtype B 3 0.8347
Gag-Pol polyprotein P12497 POL_HV1N5 Human immunodeficiency virus type 1 group M subtype B 3 0.8347
Pteridine reductase O76290 O76290_TRYBB Trypanosoma brucei brucei 3 0.8331
Pteridine reductase O76290 O76290_TRYBB Trypanosoma brucei brucei 3 0.8331
Glutathione S-transferase F2 P46422 GSTF2_ARATH Arabidopsis thaliana 3 0.8327
Glutathione S-transferase F2 P46422 GSTF2_ARATH Arabidopsis thaliana 3 0.8327
High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A O76083 PDE9A_HUMAN Homo sapiens 3 0.8289
High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A O76083 PDE9A_HUMAN Homo sapiens 3 0.8289
Tetracycline repressor protein class D P0ACT4 TETR4_ECOLX Escherichia coli 3 0.8229
Tetracycline repressor protein class D P0ACT4 TETR4_ECOLX Escherichia coli 3 0.8229
Tetracycline repressor protein class D P0ACT4 TETR4_ECOLX Escherichia coli 3 0.8197
Tetracycline repressor protein class D P0ACT4 TETR4_ECOLX Escherichia coli 3 0.8197
Serine/threonine-protein kinase Chk1 O14757 CHK1_HUMAN Homo sapiens 3 0.8196
Serine/threonine-protein kinase Chk1 O14757 CHK1_HUMAN Homo sapiens 3 0.8196
Reaction center protein L chain P0C0Y7 RCEH_RHOSH Rhodobacter sphaeroides 3 0.8180
Reaction center protein L chain P0C0Y7 RCEH_RHOSH Rhodobacter sphaeroides 3 0.8180
Succinate dehydrogenase flavoprotein subunit P0AC41 SDHA_ECOLI Escherichia coli 3 0.8169
Succinate dehydrogenase flavoprotein subunit P0AC41 SDHA_ECOLI Escherichia coli 3 0.8169
Soluble acetylcholine receptor Q8WSF8 Q8WSF8_APLCA Aplysia californica 3 0.8153
Soluble acetylcholine receptor Q8WSF8 Q8WSF8_APLCA Aplysia californica 3 0.8153
Serine/threonine-protein kinase 24 Q9Y6E0 STK24_HUMAN Homo sapiens 3 0.8137
Serine/threonine-protein kinase 24 Q9Y6E0 STK24_HUMAN Homo sapiens 3 0.8137
Tetracycline repressor protein class H P51561 TETR8_PASMD Pasteurella multocida 3 0.8125
Tetracycline repressor protein class H P51561 TETR8_PASMD Pasteurella multocida 3 0.8125
Capsid protein Q9WBP8 Q9WBP8_9VIRU Adeno-associated virus - 1 3 0.8109
Capsid protein Q9WBP8 Q9WBP8_9VIRU Adeno-associated virus - 1 3 0.8109
Peroxisome proliferator-activated receptor gamma P37231 PPARG_HUMAN Homo sapiens 4 0.8086
Peroxisome proliferator-activated receptor gamma P37231 PPARG_HUMAN Homo sapiens 4 0.8086
Tubulin alpha chain D0VWZ0 D0VWZ0_SHEEP Ovis aries 3 0.8085
Tubulin alpha chain D0VWZ0 D0VWZ0_SHEEP Ovis aries 3 0.8085
Death-associated protein kinase 1 P53355 DAPK1_HUMAN Homo sapiens 4 0.8082
Death-associated protein kinase 1 P53355 DAPK1_HUMAN Homo sapiens 4 0.8082
Bromodomain-containing protein 4 O60885 BRD4_HUMAN Homo sapiens 3 0.8081
Bromodomain-containing protein 4 O60885 BRD4_HUMAN Homo sapiens 3 0.8081
Major pollen allergen Bet v 1-A P15494 BEV1A_BETPN Betula pendula 3 0.8061
Major pollen allergen Bet v 1-A P15494 BEV1A_BETPN Betula pendula 3 0.8061
Proto-oncogene tyrosine-protein kinase Src P00523 SRC_CHICK Gallus gallus 3 0.8060
Proto-oncogene tyrosine-protein kinase Src P00523 SRC_CHICK Gallus gallus 3 0.8060
Dipeptidyl peptidase 4 P27487 DPP4_HUMAN Homo sapiens 3 0.8020
Dipeptidyl peptidase 4 P27487 DPP4_HUMAN Homo sapiens 3 0.8020
Death-associated protein kinase 1 P53355 DAPK1_HUMAN Homo sapiens 4 0.8018
Death-associated protein kinase 1 P53355 DAPK1_HUMAN Homo sapiens 4 0.8018
Aldehyde dehydrogenase, mitochondrial P05091 ALDH2_HUMAN Homo sapiens 4 0.8011
Aldehyde dehydrogenase, mitochondrial P05091 ALDH2_HUMAN Homo sapiens 4 0.8011
Isoflavone-7-O-methyltransferase 8 O24529 7OMT8_MEDSA Medicago sativa 4 0.8006
Isoflavone-7-O-methyltransferase 8 O24529 7OMT8_MEDSA Medicago sativa 4 0.8006
Mitogen-activated protein kinase 14 Q16539 MK14_HUMAN Homo sapiens 3 0.7962
Mitogen-activated protein kinase 14 Q16539 MK14_HUMAN Homo sapiens 3 0.7962
Soluble cytochrome b562 P0ABE7 C562_ECOLX Escherichia coli 3 0.7924
Soluble cytochrome b562 P0ABE7 C562_ECOLX Escherichia coli 3 0.7924
Neocarzinostatin P0A3R9 NCZS_STRCZ Streptomyces carzinostaticus 3 0.7910
Neocarzinostatin P0A3R9 NCZS_STRCZ Streptomyces carzinostaticus 3 0.7910
Genome polyprotein Q2YHF0 POLG_DEN4T Dengue virus type 4 3 0.7871
Genome polyprotein Q2YHF0 POLG_DEN4T Dengue virus type 4 3 0.7871
Heat shock protein HSP 90-alpha P07900 HS90A_HUMAN Homo sapiens 3 0.7858
Heat shock protein HSP 90-alpha P07900 HS90A_HUMAN Homo sapiens 3 0.7858
Serine/threonine-protein kinase Chk1 O14757 CHK1_HUMAN Homo sapiens 4 0.7855
Serine/threonine-protein kinase Chk1 O14757 CHK1_HUMAN Homo sapiens 4 0.7855
Carbonyl reductase [NADPH] 1 P16152 CBR1_HUMAN Homo sapiens 3 0.7848
Carbonyl reductase [NADPH] 1 P16152 CBR1_HUMAN Homo sapiens 3 0.7848
Albumin P02768 ALBU_HUMAN Homo sapiens 3 0.7837
Albumin P02768 ALBU_HUMAN Homo sapiens 3 0.7837
Poly [ADP-ribose] polymerase tankyrase-2 Q9H2K2 TNKS2_HUMAN Homo sapiens 3 0.7833
Poly [ADP-ribose] polymerase tankyrase-2 Q9H2K2 TNKS2_HUMAN Homo sapiens 3 0.7833
Biotin carboxylase P24182 ACCC_ECOLI Escherichia coli 4 0.7824
Biotin carboxylase P24182 ACCC_ECOLI Escherichia coli 4 0.7824
Tetracycline repressor protein class D P0ACT4 TETR4_ECOLX Escherichia coli 3 0.7822
Tetracycline repressor protein class D P0ACT4 TETR4_ECOLX Escherichia coli 3 0.7822
Protoporphyrinogen oxidase P50336 PPOX_HUMAN Homo sapiens 3 0.7820
Protoporphyrinogen oxidase P50336 PPOX_HUMAN Homo sapiens 3 0.7820
Mitogen-activated protein kinase 14 Q16539 MK14_HUMAN Homo sapiens 3 0.7813
Mitogen-activated protein kinase 14 Q16539 MK14_HUMAN Homo sapiens 3 0.7813
Flavonoid 3-O-glucosyltransferase A6XNC6 UGFGT_MEDTR Medicago truncatula 3 0.7805
Flavonoid 3-O-glucosyltransferase A6XNC6 UGFGT_MEDTR Medicago truncatula 3 0.7805
Acetolactate synthase, chloroplastic P17597 ILVB_ARATH Arabidopsis thaliana 3 0.7797
Acetolactate synthase, chloroplastic P17597 ILVB_ARATH Arabidopsis thaliana 3 0.7797
Chalcone--flavanone isomerase 1 P28012 CFI1_MEDSA Medicago sativa 3 0.7792
Chalcone--flavanone isomerase 1 P28012 CFI1_MEDSA Medicago sativa 3 0.7792
3-ketosteroid dehydrogenase Q9RA02 Q9RA02_RHOER Rhodococcus erythropolis 3 0.7791
3-ketosteroid dehydrogenase Q9RA02 Q9RA02_RHOER Rhodococcus erythropolis 3 0.7791
Beta-secretase 1 P56817 BACE1_HUMAN Homo sapiens 3 0.7789
Beta-secretase 1 P56817 BACE1_HUMAN Homo sapiens 3 0.7789
Gag-Pol polyprotein P03367 POL_HV1BR Human immunodeficiency virus type 1 group M subtype B 3 0.7781
Gag-Pol polyprotein P03367 POL_HV1BR Human immunodeficiency virus type 1 group M subtype B 3 0.7781
Lactotransferrin P24627 TRFL_BOVIN Bos taurus 2 0.7773
Lactotransferrin P24627 TRFL_BOVIN Bos taurus 2 0.7773
Tau-tubulin kinase 1 Q5TCY1 TTBK1_HUMAN Homo sapiens 3 0.7767
Tau-tubulin kinase 1 Q5TCY1 TTBK1_HUMAN Homo sapiens 3 0.7767
Beta-lactamase Q9L5C8 Q9L5C8_ECOLX Escherichia coli 3 0.7766
Beta-lactamase Q9L5C8 Q9L5C8_ECOLX Escherichia coli 3 0.7766
Cytochrome P450 Q93H81 Q93H81_STRAX Streptomyces avermitilis 3 0.7761
Cytochrome P450 Q93H81 Q93H81_STRAX Streptomyces avermitilis 3 0.7761
Heat shock protein HSP 90-alpha P07900 HS90A_HUMAN Homo sapiens 3 0.7761
Heat shock protein HSP 90-alpha P07900 HS90A_HUMAN Homo sapiens 3 0.7761
Serine/threonine-protein kinase pim-1 P11309 PIM1_HUMAN Homo sapiens 3 0.7754
Serine/threonine-protein kinase pim-1 P11309 PIM1_HUMAN Homo sapiens 3 0.7754
Ribosyldihydronicotinamide dehydrogenase [quinone] P16083 NQO2_HUMAN Homo sapiens 4 0.7753
Ribosyldihydronicotinamide dehydrogenase [quinone] P16083 NQO2_HUMAN Homo sapiens 4 0.7753
Death-associated protein kinase 1 P53355 DAPK1_HUMAN Homo sapiens 4 0.7753
Death-associated protein kinase 1 P53355 DAPK1_HUMAN Homo sapiens 4 0.7753
Carbonic anhydrase 2 P00918 CAH2_HUMAN Homo sapiens 3 0.7751
Carbonic anhydrase 2 P00918 CAH2_HUMAN Homo sapiens 3 0.7751
Peroxisome proliferator-activated receptor gamma P37231 PPARG_HUMAN Homo sapiens 3 0.7747
Peroxisome proliferator-activated receptor gamma P37231 PPARG_HUMAN Homo sapiens 3 0.7747
Gag-Pol polyprotein P12497 POL_HV1N5 Human immunodeficiency virus type 1 group M subtype B 3 0.7725
Gag-Pol polyprotein P12497 POL_HV1N5 Human immunodeficiency virus type 1 group M subtype B 3 0.7725
Heat shock protein HSP 90-alpha P07900 HS90A_HUMAN Homo sapiens 3 0.7718
Heat shock protein HSP 90-alpha P07900 HS90A_HUMAN Homo sapiens 3 0.7718
Riboflavin synthase P0AFU8 RISA_ECOLI Escherichia coli 3 0.7716
Riboflavin synthase P0AFU8 RISA_ECOLI Escherichia coli 3 0.7716
Rhodopsin kinase GRK1 P28327 GRK1_BOVIN Bos taurus 3 0.7664
Rhodopsin kinase GRK1 P28327 GRK1_BOVIN Bos taurus 3 0.7664
Transcriptional regulator, PadR-like family A2RI36 A2RI36_LACLM Lactococcus lactis subsp. cremoris 2 0.7641
Transcriptional regulator, PadR-like family A2RI36 A2RI36_LACLM Lactococcus lactis subsp. cremoris 2 0.7641
Serine/threonine-protein kinase pim-1 P11309 PIM1_HUMAN Homo sapiens 3 0.7640
Serine/threonine-protein kinase pim-1 P11309 PIM1_HUMAN Homo sapiens 3 0.7640
Epidermal growth factor receptor P00533 EGFR_HUMAN Homo sapiens 3 0.7632
Epidermal growth factor receptor P00533 EGFR_HUMAN Homo sapiens 3 0.7632
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial Q15119 PDK2_HUMAN Homo sapiens 3 0.7631
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial Q15119 PDK2_HUMAN Homo sapiens 3 0.7631
Alpha-ketoglutarate-dependent dioxygenase FTO Q9C0B1 FTO_HUMAN Homo sapiens 3 0.7615
Alpha-ketoglutarate-dependent dioxygenase FTO Q9C0B1 FTO_HUMAN Homo sapiens 3 0.7615
HTH-type transcriptional repressor PurR P0ACP7 PURR_ECOLI Escherichia coli 3 0.7607
HTH-type transcriptional repressor PurR P0ACP7 PURR_ECOLI Escherichia coli 3 0.7607
Glucan 1,3-beta-glucosidase P29717 EXG1_CANAL Candida albicans 2 0.7602
Glucan 1,3-beta-glucosidase P29717 EXG1_CANAL Candida albicans 2 0.7602
Ephrin type-A receptor 4 Q03137 EPHA4_MOUSE Mus musculus 4 0.7597
Ephrin type-A receptor 4 Q03137 EPHA4_MOUSE Mus musculus 4 0.7597
Beta sliding clamp P0A988 DPO3B_ECOLI Escherichia coli 2 0.7589
Beta sliding clamp P0A988 DPO3B_ECOLI Escherichia coli 2 0.7589
Estrogen receptor beta Q92731 ESR2_HUMAN Homo sapiens 3 0.7575
Estrogen receptor beta Q92731 ESR2_HUMAN Homo sapiens 3 0.7575
Mitogen-activated protein kinase 14 Q16539 MK14_HUMAN Homo sapiens 3 0.7568
Mitogen-activated protein kinase 14 Q16539 MK14_HUMAN Homo sapiens 3 0.7568
CREB-binding protein Q92793 CBP_HUMAN Homo sapiens 3 0.7565
CREB-binding protein Q92793 CBP_HUMAN Homo sapiens 3 0.7565
Tyrosine-protein kinase JAK2 O60674 JAK2_HUMAN Homo sapiens 3 0.7554
Tyrosine-protein kinase JAK2 O60674 JAK2_HUMAN Homo sapiens 3 0.7554
Caspase-3 P42574 CASP3_HUMAN Homo sapiens 2 0.7540
Caspase-3 P42574 CASP3_HUMAN Homo sapiens 2 0.7540
ActVA 6 protein Q53908 Q53908_STRCH Streptomyces coelicolor 3 0.7536
ActVA 6 protein Q53908 Q53908_STRCH Streptomyces coelicolor 3 0.7536
Mitogen-activated protein kinase 14 Q16539 MK14_HUMAN Homo sapiens 3 0.7532
Mitogen-activated protein kinase 14 Q16539 MK14_HUMAN Homo sapiens 3 0.7532
cGMP-specific 3',5'-cyclic phosphodiesterase O76074 PDE5A_HUMAN Homo sapiens 3 0.7514
cGMP-specific 3',5'-cyclic phosphodiesterase O76074 PDE5A_HUMAN Homo sapiens 3 0.7514
Estrogen receptor beta Q92731 ESR2_HUMAN Homo sapiens 3 0.7511
Estrogen receptor beta Q92731 ESR2_HUMAN Homo sapiens 3 0.7511
Acetolactate synthase, chloroplastic P17597 ILVB_ARATH Arabidopsis thaliana 3 0.7503
Acetolactate synthase, chloroplastic P17597 ILVB_ARATH Arabidopsis thaliana 3 0.7503
HTH-type transcriptional repressor PurR P0ACP7 PURR_ECOLI Escherichia coli 3 0.7500
HTH-type transcriptional repressor PurR P0ACP7 PURR_ECOLI Escherichia coli 3 0.7500
Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase Q05603 COBT_SALTY Salmonella typhimurium 2 0.7498
Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase Q05603 COBT_SALTY Salmonella typhimurium 2 0.7498
Casein kinase II subunit alpha P68400 CSK21_HUMAN Homo sapiens 3 0.7494
Casein kinase II subunit alpha P68400 CSK21_HUMAN Homo sapiens 3 0.7494
Nuclear receptor subfamily 1 group I member 2 O75469 NR1I2_HUMAN Homo sapiens 3 0.7483
Nuclear receptor subfamily 1 group I member 2 O75469 NR1I2_HUMAN Homo sapiens 3 0.7483
HTH-type transcriptional regulator TtgR Q9AIU0 TTGR_PSEPT Pseudomonas putida 3 0.7471
HTH-type transcriptional regulator TtgR Q9AIU0 TTGR_PSEPT Pseudomonas putida 3 0.7471
Aldo-keto reductase family 1 member B1 P15121 ALDR_HUMAN Homo sapiens 2 0.7455
Aldo-keto reductase family 1 member B1 P15121 ALDR_HUMAN Homo sapiens 2 0.7455
Liver carboxylesterase 1 P23141 EST1_HUMAN Homo sapiens 3 0.7445
Liver carboxylesterase 1 P23141 EST1_HUMAN Homo sapiens 3 0.7445
Gag-Pol polyprotein O12158 POL_HV192 Human immunodeficiency virus type 1 group M subtype C 3 0.7440
Gag-Pol polyprotein O12158 POL_HV192 Human immunodeficiency virus type 1 group M subtype C 3 0.7440
Chalcone--flavanone isomerase 1 P28012 CFI1_MEDSA Medicago sativa 3 0.7439
4-hydroxyphenylacetate 3-monooxygenase Q8YHT7 Q8YHT7_BRUME Brucella melitensis biotype 1 2 0.7439
Chalcone--flavanone isomerase 1 P28012 CFI1_MEDSA Medicago sativa 3 0.7439
4-hydroxyphenylacetate 3-monooxygenase Q8YHT7 Q8YHT7_BRUME Brucella melitensis biotype 1 2 0.7439
Basic phospholipase A2 VRV-PL-VIIIa P59071 PA2B8_DABRR Daboia russelii 2 0.7434
Basic phospholipase A2 VRV-PL-VIIIa P59071 PA2B8_DABRR Daboia russelii 2 0.7434
Cyclin-dependent kinase 9 P50750 CDK9_HUMAN Homo sapiens 3 0.7421
Cyclin-dependent kinase 9 P50750 CDK9_HUMAN Homo sapiens 3 0.7421
Pantothenate synthetase P9WIL5 PANC_MYCTU Mycobacterium tuberculosis 3 0.7420
Pantothenate synthetase P9WIL5 PANC_MYCTU Mycobacterium tuberculosis 3 0.7420
Serine/threonine-protein kinase pim-1 P11309 PIM1_HUMAN Homo sapiens 3 0.7410
Serine/threonine-protein kinase pim-1 P11309 PIM1_HUMAN Homo sapiens 3 0.7410
Glycogen synthase kinase-3 beta P49841 GSK3B_HUMAN Homo sapiens 3 0.7408
Glycogen synthase kinase-3 beta P49841 GSK3B_HUMAN Homo sapiens 3 0.7408
TetR family transcriptional regulator Q58L87 Q58L87_MYCSM Mycolicibacterium smegmatis 2 0.7405
Homoserine dehydrogenase P31116 DHOM_YEAST Saccharomyces cerevisiae 3 0.7405
TetR family transcriptional regulator Q58L87 Q58L87_MYCSM Mycolicibacterium smegmatis 2 0.7405
Homoserine dehydrogenase P31116 DHOM_YEAST Saccharomyces cerevisiae 3 0.7405
Glucose-1-phosphate thymidylyltransferase Q9HU22 Q9HU22_PSEAE Pseudomonas aeruginosa 3 0.7382
Glucose-1-phosphate thymidylyltransferase Q9HU22 Q9HU22_PSEAE Pseudomonas aeruginosa 3 0.7382
Ephrin type-B receptor 2 P54763 EPHB2_MOUSE Mus musculus 3 0.7379
Ephrin type-B receptor 2 P54763 EPHB2_MOUSE Mus musculus 3 0.7379
Phosphatidylinositol 5-phosphate 4-kinase type-2 beta P78356 PI42B_HUMAN Homo sapiens 3 0.7370
Phosphatidylinositol 5-phosphate 4-kinase type-2 beta P78356 PI42B_HUMAN Homo sapiens 3 0.7370
FMN-dependent NAD(P)H:quinone oxidoreductase 1 Q9I5F3 AZOR1_PSEAE Pseudomonas aeruginosa 2 0.7362
FMN-dependent NAD(P)H:quinone oxidoreductase 1 Q9I5F3 AZOR1_PSEAE Pseudomonas aeruginosa 2 0.7362
S-adenosylmethionine decarboxylase proenzyme P17707 DCAM_HUMAN Homo sapiens 3 0.7357
S-adenosylmethionine decarboxylase proenzyme P17707 DCAM_HUMAN Homo sapiens 3 0.7357
Calmodulin-like domain protein kinase isoenzyme gamma, related F0V9W9 F0V9W9_NEOCL Neospora caninum 3 0.7353
Calmodulin-like domain protein kinase isoenzyme gamma, related F0V9W9 F0V9W9_NEOCL Neospora caninum 3 0.7353
Estrogen receptor beta Q92731 ESR2_HUMAN Homo sapiens 3 0.7350
Estrogen receptor beta Q92731 ESR2_HUMAN Homo sapiens 3 0.7350
Bromodomain protein, putative Q8I240 Q8I240_PLAF7 Plasmodium falciparum 4 0.7347
Bromodomain protein, putative Q8I240 Q8I240_PLAF7 Plasmodium falciparum 4 0.7347
NTPase P4 Q94M05 Q94M05_9VIRU Pseudomonas phage phi12 3 0.7346
NTPase P4 Q94M05 Q94M05_9VIRU Pseudomonas phage phi12 3 0.7346
Mitogen-activated protein kinase 14 Q16539 MK14_HUMAN Homo sapiens 3 0.7344
Mitogen-activated protein kinase 14 Q16539 MK14_HUMAN Homo sapiens 3 0.7344
Phosphodiesterase Q8WQX9 Q8WQX9_9TRYP Trypanosoma brucei 3 0.7340
Phosphodiesterase Q8WQX9 Q8WQX9_9TRYP Trypanosoma brucei 3 0.7340
Casein kinase II subunit alpha P68400 CSK21_HUMAN Homo sapiens 3 0.7337
Casein kinase II subunit alpha P68400 CSK21_HUMAN Homo sapiens 3 0.7337
Carbonic anhydrase 2 P00918 CAH2_HUMAN Homo sapiens 2 0.7319
Basic phospholipase A2 VRV-PL-VIIIa P59071 PA2B8_DABRR Daboia russelii 3 0.7319
Carbonic anhydrase 2 P00918 CAH2_HUMAN Homo sapiens 2 0.7319
Basic phospholipase A2 VRV-PL-VIIIa P59071 PA2B8_DABRR Daboia russelii 3 0.7319
Pheromone-binding protein ASP1 Q9U9J6 Q9U9J6_APIME Apis mellifera 2 0.7318
Pheromone-binding protein ASP1 Q9U9J6 Q9U9J6_APIME Apis mellifera 2 0.7318
2',3'-cyclic-nucleotide 3'-phosphodiesterase P16330 CN37_MOUSE Mus musculus 2 0.7313
2',3'-cyclic-nucleotide 3'-phosphodiesterase P16330 CN37_MOUSE Mus musculus 2 0.7313
Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplastic Q43088 RBCMT_PEA Pisum sativum 4 0.7307
Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplastic Q43088 RBCMT_PEA Pisum sativum 4 0.7307
Beta-secretase 1 P56817 BACE1_HUMAN Homo sapiens 3 0.7306
Beta-secretase 1 P56817 BACE1_HUMAN Homo sapiens 3 0.7306
Secoisolariciresinol dehydrogenase Q94KL8 SILD_PODPE Podophyllum peltatum 4 0.7305
Secoisolariciresinol dehydrogenase Q94KL8 SILD_PODPE Podophyllum peltatum 4 0.7305
Serine/threonine-protein kinase PLK1 P53350 PLK1_HUMAN Homo sapiens 3 0.7304
Serine/threonine-protein kinase PLK1 P53350 PLK1_HUMAN Homo sapiens 3 0.7304
APH(2'')-Id O68183 O68183_ENTCA Enterococcus casseliflavus 4 0.7296
APH(2'')-Id O68183 O68183_ENTCA Enterococcus casseliflavus 4 0.7296
Casein kinase II subunit alpha P68400 CSK21_HUMAN Homo sapiens 4 0.7282
Casein kinase II subunit alpha P68400 CSK21_HUMAN Homo sapiens 4 0.7282
Nitric oxide synthase oxygenase O34453 NOSO_BACSU Bacillus subtilis 3 0.7262
Nitric oxide synthase oxygenase O34453 NOSO_BACSU Bacillus subtilis 3 0.7262
Methionine adenosyltransferase 2 subunit beta Q9NZL9 MAT2B_HUMAN Homo sapiens 4 0.7260
Methionine adenosyltransferase 2 subunit beta Q9NZL9 MAT2B_HUMAN Homo sapiens 4 0.7260
Bromodomain-containing protein 4 O60885 BRD4_HUMAN Homo sapiens 3 0.7255
Bromodomain-containing protein 4 O60885 BRD4_HUMAN Homo sapiens 3 0.7255
Mitogen-activated protein kinase 8 P45983 MK08_HUMAN Homo sapiens 3 0.7253
Mitogen-activated protein kinase 8 P45983 MK08_HUMAN Homo sapiens 3 0.7253
tyrosine--tRNA ligase Q4QFJ7 Q4QFJ7_LEIMA Leishmania major 3 0.7252
tyrosine--tRNA ligase Q4QFJ7 Q4QFJ7_LEIMA Leishmania major 3 0.7252
Mitogen-activated protein kinase 14 Q16539 MK14_HUMAN Homo sapiens 3 0.7244
Mitogen-activated protein kinase 14 Q16539 MK14_HUMAN Homo sapiens 3 0.7244
Carbonic anhydrase 2 P00918 CAH2_HUMAN Homo sapiens 2 0.7243
Carbonic anhydrase 2 P00918 CAH2_HUMAN Homo sapiens 2 0.7243
Estrogen receptor P03372 ESR1_HUMAN Homo sapiens 3 0.7232
Estrogen receptor P03372 ESR1_HUMAN Homo sapiens 3 0.7232
High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A O76083 PDE9A_HUMAN Homo sapiens 3 0.7229
High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A O76083 PDE9A_HUMAN Homo sapiens 3 0.7229
Protein S100-A13 Q99584 S10AD_HUMAN Homo sapiens 3 0.7228
Protein S100-A13 Q99584 S10AD_HUMAN Homo sapiens 3 0.7228
Tetracycline repressor protein class D P0ACT4 TETR4_ECOLX Escherichia coli 3 0.7227
Tetracycline repressor protein class D P0ACT4 TETR4_ECOLX Escherichia coli 3 0.7227
Urokinase-type plasminogen activator P00749 UROK_HUMAN Homo sapiens 2 0.7225
Urokinase-type plasminogen activator P00749 UROK_HUMAN Homo sapiens 2 0.7225
Serine/threonine-protein kinase Chk1 O14757 CHK1_HUMAN Homo sapiens 3 0.7223
Serine/threonine-protein kinase Chk1 O14757 CHK1_HUMAN Homo sapiens 3 0.7223
Chalcone synthase 2 P30074 CHS2_MEDSA Medicago sativa 3 0.7222
Chalcone synthase 2 P30074 CHS2_MEDSA Medicago sativa 3 0.7222
Basic phospholipase A2 VRV-PL-VIIIa P59071 PA2B8_DABRR Daboia russelii 2 0.7220
Basic phospholipase A2 VRV-PL-VIIIa P59071 PA2B8_DABRR Daboia russelii 2 0.7220
DNA topoisomerase 4 subunit B H7C794 PARE_ENTFA Enterococcus faecalis 2 0.7202
DNA topoisomerase 4 subunit B H7C794 PARE_ENTFA Enterococcus faecalis 2 0.7202
Beta-1 adrenergic receptor P07700 ADRB1_MELGA Meleagris gallopavo 2 0.7197
Beta-1 adrenergic receptor P07700 ADRB1_MELGA Meleagris gallopavo 2 0.7197
ABC-type polar amino acid transport system, ATPase component Q8RCC2 Q8RCC2_CALS4 Caldanaerobacter subterraneus subsp. tengcongensis 2 0.7193
ABC-type polar amino acid transport system, ATPase component Q8RCC2 Q8RCC2_CALS4 Caldanaerobacter subterraneus subsp. tengcongensis 2 0.7193
Enoyl-[acyl-carrier-protein] reductase [NADH], chloroplastic P80030 FABI_BRANA Brassica napus 4 0.7184
Enoyl-[acyl-carrier-protein] reductase [NADH], chloroplastic P80030 FABI_BRANA Brassica napus 4 0.7184
Polymerase acidic protein C3W5S0 C3W5S0_I09A0 Influenza A virus 2 0.7178
Polymerase acidic protein C3W5S0 C3W5S0_I09A0 Influenza A virus 2 0.7178
Gag-Pol polyprotein P03367 POL_HV1BR Human immunodeficiency virus type 1 group M subtype B 3 0.7171
Gag-Pol polyprotein P03367 POL_HV1BR Human immunodeficiency virus type 1 group M subtype B 3 0.7171
Serine/threonine-protein kinase pim-1 P11309 PIM1_HUMAN Homo sapiens 3 0.7167
Serine/threonine-protein kinase pim-1 P11309 PIM1_HUMAN Homo sapiens 3 0.7167
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform P48736 PK3CG_HUMAN Homo sapiens 4 0.7155
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform P48736 PK3CG_HUMAN Homo sapiens 4 0.7155
Aminoglycoside N(3)-acetyltransferase A0A3P1UCA6 Q81P86_BACAN Bacillus anthracis 3 0.7150
Aminoglycoside N(3)-acetyltransferase A0A3P1UCA6 Q81P86_BACAN Bacillus anthracis 3 0.7150
2',3'-cyclic-nucleotide 3'-phosphodiesterase P16330 CN37_MOUSE Mus musculus 2 0.7143
2',3'-cyclic-nucleotide 3'-phosphodiesterase P16330 CN37_MOUSE Mus musculus 2 0.7143
Glycogen phosphorylase, muscle form P00489 PYGM_RABIT Oryctolagus cuniculus 3 0.7138
Glycogen phosphorylase, muscle form P00489 PYGM_RABIT Oryctolagus cuniculus 3 0.7138
Ribonuclease TTHA0252 Q5SLP1 RNSE_THET8 Thermus thermophilus 3 0.7126
Ribonuclease TTHA0252 Q5SLP1 RNSE_THET8 Thermus thermophilus 3 0.7126
Non-receptor tyrosine-protein kinase TYK2 P29597 TYK2_HUMAN Homo sapiens 3 0.7120
Non-receptor tyrosine-protein kinase TYK2 P29597 TYK2_HUMAN Homo sapiens 3 0.7120
Carbonic anhydrase 2 P00918 CAH2_HUMAN Homo sapiens 3 0.7118
Carbonic anhydrase 2 P00918 CAH2_HUMAN Homo sapiens 3 0.7118
Carbonyl reductase [NADPH] 1 P16152 CBR1_HUMAN Homo sapiens 3 0.7110
Beta-secretase 2 Q9Y5Z0 BACE2_HUMAN Homo sapiens 2 0.7110
Carbonyl reductase [NADPH] 1 P16152 CBR1_HUMAN Homo sapiens 3 0.7110
Beta-secretase 2 Q9Y5Z0 BACE2_HUMAN Homo sapiens 2 0.7110
Carbonic anhydrase 2 P00918 CAH2_HUMAN Homo sapiens 2 0.7105
Carbonic anhydrase 2 P00918 CAH2_HUMAN Homo sapiens 2 0.7105
Cytochrome P450 2D6 P10635 CP2D6_HUMAN Homo sapiens 3 0.7101
Serine/threonine-protein kinase Chk1 O14757 CHK1_HUMAN Homo sapiens 3 0.7101
Cytochrome P450 2D6 P10635 CP2D6_HUMAN Homo sapiens 3 0.7101
Serine/threonine-protein kinase Chk1 O14757 CHK1_HUMAN Homo sapiens 3 0.7101
Mitogen-activated protein kinase 1 P28482 MK01_HUMAN Homo sapiens 3 0.7100
Mitogen-activated protein kinase 1 P28482 MK01_HUMAN Homo sapiens 3 0.7100
Enoyl-[acyl-carrier-protein] reductase [NADH] P9WGR1 INHA_MYCTU Mycobacterium tuberculosis 3 0.7092
Enoyl-[acyl-carrier-protein] reductase [NADH] P9WGR1 INHA_MYCTU Mycobacterium tuberculosis 3 0.7092
Neuropilin-1 O14786 NRP1_HUMAN Homo sapiens 3 0.7090
Neuropilin-1 O14786 NRP1_HUMAN Homo sapiens 3 0.7090
Peroxisome proliferator-activated receptor gamma P37231 PPARG_HUMAN Homo sapiens 2 0.7071
Peroxisome proliferator-activated receptor gamma P37231 PPARG_HUMAN Homo sapiens 2 0.7071
Steroid Delta-isomerase P00947 SDIS_COMTE Comamonas testosteroni 3 0.7063
Steroid Delta-isomerase P00947 SDIS_COMTE Comamonas testosteroni 3 0.7063
Beta-secretase 1 P56817 BACE1_HUMAN Homo sapiens 2 0.7063
ATP synthase subunit alpha, mitochondrial P19483 ATPA_BOVIN Bos taurus 3 0.7063
ATP synthase subunit alpha, mitochondrial P19483 ATPA_BOVIN Bos taurus 3 0.7063
Beta-secretase 1 P56817 BACE1_HUMAN Homo sapiens 2 0.7063
Serine/threonine-protein kinase Chk2 O96017 CHK2_HUMAN Homo sapiens 2 0.7057
Serine/threonine-protein kinase Chk2 O96017 CHK2_HUMAN Homo sapiens 2 0.7057
Pantothenate kinase P9WPA7 COAA_MYCTU Mycobacterium tuberculosis 3 0.7057
Pantothenate kinase P9WPA7 COAA_MYCTU Mycobacterium tuberculosis 3 0.7057
Fibroblast growth factor receptor 2 P21802 FGFR2_HUMAN Homo sapiens 3 0.7053
Fibroblast growth factor receptor 2 P21802 FGFR2_HUMAN Homo sapiens 3 0.7053
NADPH-dependent oxidoreductase 2-alkenal reductase Q39172 AER_ARATH Arabidopsis thaliana 2 0.7038
NADPH-dependent oxidoreductase 2-alkenal reductase Q39172 AER_ARATH Arabidopsis thaliana 2 0.7038
Leucoanthocyanidin dioxygenase Q96323 LDOX_ARATH Arabidopsis thaliana 4 0.7036
Leucoanthocyanidin dioxygenase Q96323 LDOX_ARATH Arabidopsis thaliana 4 0.7036
Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplastic Q43088 RBCMT_PEA Pisum sativum 4 0.7035
Mitogen-activated protein kinase 14 Q16539 MK14_HUMAN Homo sapiens 3 0.7035
Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplastic Q43088 RBCMT_PEA Pisum sativum 4 0.7035
Mitogen-activated protein kinase 14 Q16539 MK14_HUMAN Homo sapiens 3 0.7035
Thymidylate synthase P00469 TYSY_LACCA Lacticaseibacillus casei 2 0.7034
Thymidylate synthase P00469 TYSY_LACCA Lacticaseibacillus casei 2 0.7034
Aldo-keto reductase family 1 member C3 P42330 AK1C3_HUMAN Homo sapiens 2 0.7032
Aldo-keto reductase family 1 member C3 P42330 AK1C3_HUMAN Homo sapiens 2 0.7032
Focal adhesion kinase 1 Q00944 FAK1_CHICK Gallus gallus 3 0.7028
Bromodomain-containing protein 2 P25440 BRD2_HUMAN Homo sapiens 3 0.7028
Bromodomain-containing protein 2 P25440 BRD2_HUMAN Homo sapiens 3 0.7028
Focal adhesion kinase 1 Q00944 FAK1_CHICK Gallus gallus 3 0.7028
Chalcone synthase 2 P30074 CHS2_MEDSA Medicago sativa 4 0.7027
Chalcone synthase 2 P30074 CHS2_MEDSA Medicago sativa 4 0.7027
Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplastic Q43088 RBCMT_PEA Pisum sativum 3 0.7024
Photosynthetic reaction center cytochrome c subunit P07173 CYCR_BLAVI Blastochloris viridis 2 0.7024
Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplastic Q43088 RBCMT_PEA Pisum sativum 3 0.7024
Photosynthetic reaction center cytochrome c subunit P07173 CYCR_BLAVI Blastochloris viridis 2 0.7024
Serine/threonine-protein kinase Chk1 O14757 CHK1_HUMAN Homo sapiens 3 0.7019
Serine/threonine-protein kinase Chk1 O14757 CHK1_HUMAN Homo sapiens 3 0.7019
Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial Q33862 Q33862_ASCSU Ascaris suum 3 0.7018
Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial Q33862 Q33862_ASCSU Ascaris suum 3 0.7018
Proto-oncogene tyrosine-protein kinase receptor Ret P07949 RET_HUMAN Homo sapiens 3 0.7016
Proto-oncogene tyrosine-protein kinase receptor Ret P07949 RET_HUMAN Homo sapiens 3 0.7016
Chalcone--flavanone isomerase 1 P28012 CFI1_MEDSA Medicago sativa 3 0.7013
Chalcone--flavanone isomerase 1 P28012 CFI1_MEDSA Medicago sativa 3 0.7013
Avidin P02701 AVID_CHICK Gallus gallus 2 0.7008
Avidin P02701 AVID_CHICK Gallus gallus 2 0.7008
Maltokinase A1TH50 MAK_MYCVP Mycolicibacterium vanbaalenii 3 0.7003
Maltokinase A1TH50 MAK_MYCVP Mycolicibacterium vanbaalenii 3 0.7003
Hygromycin-B 4-O-kinase P00557 KHYB_ECOLX Escherichia coli 3 0.7001
Hygromycin-B 4-O-kinase P00557 KHYB_ECOLX Escherichia coli 3 0.7001

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