3,7-dihydroxy-5,8-dimethoxyflavanone - Compound Card

3,7-dihydroxy-5,8-dimethoxyflavanone

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3,7-dihydroxy-5,8-dimethoxyflavanone

Structure
Zoomed Structure
  • Family: Plantae - Polygonaceae
  • Kingdom: Plantae
  • Class: Flavonoid
Canonical Smiles COc1c(O)cc(c2c1OC(c1ccccc1)C(C2=O)O)OC
InChI InChI=1S/C17H16O6/c1-21-11-8-10(18)16(22-2)17-12(11)13(19)14(20)15(23-17)9-6-4-3-5-7-9/h3-8,14-15,18,20H,1-2H3
InChIKey HYJUDFUDRHMLNZ-UHFFFAOYSA-N
Formula C17H16O6
HBA 6
HBD 2
MW 316.31
Rotatable Bonds 3
TPSA 85.22
LogP 2.09
Number Rings 3
Number Aromatic Rings 2
Heavy Atom Count 23
Formal Charge 0
Fraction CSP3 0.24
Exact Mass 316.09
Number of Lipinski Rule Violations 0
# Species Family Kingdom NCBI Taxonomy ID
1 Polygonum senegalense Polygonaceae Plantae 471708

Showing of synonyms

  • Midiwo JO, Gikonyo NK, et al. (1992). Flavonoids of Polygonum senegalense (Meisn) Part II: More surface and internal tissue flavonoid aglycones.. Bulletin of the Chemical Society of Ethiopia,1992,6(2),119-122. [View] [PubMed]
Pubchem: 4984593

No compound-protein relationship available.

Structure

SMILES: c1cccc(c12)OC(CC2=O)c3ccccc3

Level: 1

Mol. Weight: 316.31 g/mol

Structure

SMILES: c1cccc(c12)OCCC2=O

Level: 0

Mol. Weight: 316.31 g/mol

Structure

SMILES: c1ccccc1

Level: 0

Mol. Weight: 316.31 g/mol

No bioactivities available.

Absorption

Caco-2 (logPapp)
-4.44
Human Oral Bioavailability 20%
Bioavailable
Human Intestinal Absorption
Absorbed
Madin-Darby Canine Kidney
-4.550
Human Oral Bioavailability 50%
Bioavailable
P-Glycoprotein Inhibitor
Inhibitor
P-Glycoprotein Substrate
Non-Substrate
Skin Permeability
-2.1

Distribution

Blood-Brain Barrier (CNS)
-
Blood-Brain Barrier
Non-Penetrable
Fraction Unbound (Human)
1.140
Plasma Protein Binding
50.88
Steady State Volume of Distribution
-

Metabolism

Breast Cancer Resistance Protein
Non-Inhibitor
CYP 1A2 Inhibitor
Non-Inhibitor
CYP 1A2 Substrate
Substrate
CYP 2C19 Inhibitor
Inhibitor
CYP 2C19 Substrate
Non-Substrate
CYP 2C9 Inhibitor
Non-Inhibitor
CYP 2C9 Substrate
Substrate
CYP 2D6 Inhibitor
Non-Inhibitor
CYP 2D6 Substrate
Non-Substrate
CYP 3A4 Inhibitor
Non-Inhibitor
CYP 3A4 Substrate
Non-Substrate
OATP1B1
Non-Inhibitor
OATP1B3
Non-Inhibitor

Excretion

Clearance
9.390
Organic Cation Transporter 2
Non-Inhibitor
Half-Life of Drug
-

Toxicity

AMES Mutagenesis
Safe
Avian
Safe
Bee
Toxic
Bioconcentration Factor
0.940
Biodegradation
Safe
Carcinogenesis
Safe
Crustacean
Toxic
Liver Injury I (DILI)
Safe
Eye Corrosion
Safe
Eye Irritation
Safe
Maximum Tolerated Dose
0.970
Liver Injury II
Toxic
hERG Blockers
Safe
Daphnia Maga
5.570
Micronucleos
Toxic
NR-AhR
Toxic
NR-AR
Safe
NR-AR-LBD
Safe
NR-Aromatase
Safe
NR-ER
Safe
NR-ER-LBD
Safe
NR-GR
Safe
NR-PPAR-gamma
Safe
NR-TR
Safe
T. Pyriformis
3.100
Rat (Acute)
2.080
Rat (Chronic Oral)
2.510
Fathead Minnow
4.490
Respiratory Disease
Safe
Skin Sensitisation
Safe
SR-ARE
Safe
SR-ATAD5
Safe
SR-HSE
Safe
SR-MMP
Safe
SR-p53
Safe

General Properties

Boiling Point
385.900
Hydration Free Energy
-7.550
Log(D) at pH=7.4
1.970
Log(P)
1.97
Log S
-3.87
Log(Vapor Pressure)
-7.16
Melting Point
156.58
pKa Acid
6.55
pKa Basic
1.04
Protein Name UniProt ID Entry Name Species #Pharmacophore Points Probability (0.7 ≤ Tversky Score ≤ 1.0)
Epidermal growth factor receptor P00533 EGFR_HUMAN Homo sapiens 3 0.9608
Epidermal growth factor receptor P00533 EGFR_HUMAN Homo sapiens 3 0.9608
Poly [ADP-ribose] polymerase tankyrase-2 Q9H2K2 TNKS2_HUMAN Homo sapiens 5 0.9441
Poly [ADP-ribose] polymerase tankyrase-2 Q9H2K2 TNKS2_HUMAN Homo sapiens 5 0.9441
Epidermal growth factor receptor P00533 EGFR_HUMAN Homo sapiens 3 0.9400
Epidermal growth factor receptor P00533 EGFR_HUMAN Homo sapiens 3 0.9400
Anthocyanidin 3-O-glucosyltransferase UFGT P51094 UFOG_VITVI Vitis vinifera 5 0.9362
Anthocyanidin 3-O-glucosyltransferase UFGT P51094 UFOG_VITVI Vitis vinifera 5 0.9362
Toxoflavin degrading enzyme E3SET7 E3SET7_PAEPO Paenibacillus polymyxa 3 0.9236
Toxoflavin degrading enzyme E3SET7 E3SET7_PAEPO Paenibacillus polymyxa 3 0.9236
D-aminoacyl-tRNA deacylase Q8IIS0 DTD_PLAF7 Plasmodium falciparum 3 0.9220
D-aminoacyl-tRNA deacylase Q8IIS0 DTD_PLAF7 Plasmodium falciparum 3 0.9220
Chitinase A Q9AMP1 Q9AMP1_VIBHA Vibrio harveyi 3 0.9201
Chitinase A Q9AMP1 Q9AMP1_VIBHA Vibrio harveyi 3 0.9201
Protein polybromo-1 Q86U86 PB1_HUMAN Homo sapiens 5 0.9185
Protein polybromo-1 Q86U86 PB1_HUMAN Homo sapiens 5 0.9185
Anthocyanidin 3-O-glucosyltransferase UFGT P51094 UFOG_VITVI Vitis vinifera 4 0.9165
Anthocyanidin 3-O-glucosyltransferase UFGT P51094 UFOG_VITVI Vitis vinifera 4 0.9165
Serine/threonine-protein kinase 24 Q9Y6E0 STK24_HUMAN Homo sapiens 3 0.9116
Serine/threonine-protein kinase 24 Q9Y6E0 STK24_HUMAN Homo sapiens 3 0.9116
Heat shock protein HSP 90-alpha P07900 HS90A_HUMAN Homo sapiens 3 0.9071
Heat shock protein HSP 90-alpha P07900 HS90A_HUMAN Homo sapiens 3 0.9071
Heat shock protein HSP 90-alpha P07900 HS90A_HUMAN Homo sapiens 3 0.9061
Heat shock protein HSP 90-alpha P07900 HS90A_HUMAN Homo sapiens 3 0.9061
Poly [ADP-ribose] polymerase tankyrase-2 Q9H2K2 TNKS2_HUMAN Homo sapiens 4 0.9034
Poly [ADP-ribose] polymerase tankyrase-2 Q9H2K2 TNKS2_HUMAN Homo sapiens 4 0.9034
Bromodomain-containing protein 2 P25440 BRD2_HUMAN Homo sapiens 4 0.9010
Bromodomain-containing protein 2 P25440 BRD2_HUMAN Homo sapiens 4 0.9010
Quercetin 2,3-dioxygenase Q7SIC2 QDOI_ASPJA Aspergillus japonicus 4 0.8898
Quercetin 2,3-dioxygenase Q7SIC2 QDOI_ASPJA Aspergillus japonicus 4 0.8898
Cytochrome P450 1A1 P04798 CP1A1_HUMAN Homo sapiens 3 0.8892
Cytochrome P450 1A1 P04798 CP1A1_HUMAN Homo sapiens 3 0.8892
Mitogen-activated protein kinase 14 Q16539 MK14_HUMAN Homo sapiens 4 0.8860
Mitogen-activated protein kinase 14 Q16539 MK14_HUMAN Homo sapiens 4 0.8860
Poly [ADP-ribose] polymerase tankyrase-2 Q9H2K2 TNKS2_HUMAN Homo sapiens 4 0.8824
Poly [ADP-ribose] polymerase tankyrase-2 Q9H2K2 TNKS2_HUMAN Homo sapiens 4 0.8824
Poly [ADP-ribose] polymerase tankyrase-2 Q9H2K2 TNKS2_HUMAN Homo sapiens 4 0.8824
Poly [ADP-ribose] polymerase tankyrase-2 Q9H2K2 TNKS2_HUMAN Homo sapiens 4 0.8824
Cytohesin-2 Q99418 CYH2_HUMAN Homo sapiens 3 0.8813
Cytohesin-2 Q99418 CYH2_HUMAN Homo sapiens 3 0.8813
Poly [ADP-ribose] polymerase tankyrase-2 Q9H2K2 TNKS2_HUMAN Homo sapiens 4 0.8804
Poly [ADP-ribose] polymerase tankyrase-2 Q9H2K2 TNKS2_HUMAN Homo sapiens 4 0.8804
Rhodopsin kinase GRK1 P28327 GRK1_BOVIN Bos taurus 3 0.8803
Rhodopsin kinase GRK1 P28327 GRK1_BOVIN Bos taurus 3 0.8803
Nodulin-13 P93330 NOD13_MEDTR Medicago truncatula 3 0.8799
Nodulin-13 P93330 NOD13_MEDTR Medicago truncatula 3 0.8799
Tyrosine-protein kinase SYK P43405 KSYK_HUMAN Homo sapiens 4 0.8735
Tyrosine-protein kinase SYK P43405 KSYK_HUMAN Homo sapiens 4 0.8735
Poly [ADP-ribose] polymerase tankyrase-2 Q9H2K2 TNKS2_HUMAN Homo sapiens 4 0.8733
Poly [ADP-ribose] polymerase tankyrase-2 Q9H2K2 TNKS2_HUMAN Homo sapiens 4 0.8733
Fibroblast growth factor receptor 2 P21802 FGFR2_HUMAN Homo sapiens 3 0.8721
Fibroblast growth factor receptor 2 P21802 FGFR2_HUMAN Homo sapiens 3 0.8721
Poly [ADP-ribose] polymerase tankyrase-2 Q9H2K2 TNKS2_HUMAN Homo sapiens 5 0.8718
Poly [ADP-ribose] polymerase tankyrase-2 Q9H2K2 TNKS2_HUMAN Homo sapiens 5 0.8718
Poly [ADP-ribose] polymerase tankyrase-2 Q9H2K2 TNKS2_HUMAN Homo sapiens 4 0.8715
Poly [ADP-ribose] polymerase tankyrase-2 Q9H2K2 TNKS2_HUMAN Homo sapiens 4 0.8715
Heat shock protein HSP 90-alpha P07900 HS90A_HUMAN Homo sapiens 3 0.8705
Heat shock protein HSP 90-alpha P07900 HS90A_HUMAN Homo sapiens 3 0.8705
Fibroblast growth factor receptor 2 P21802 FGFR2_HUMAN Homo sapiens 3 0.8649
Fibroblast growth factor receptor 2 P21802 FGFR2_HUMAN Homo sapiens 3 0.8649
Poly [ADP-ribose] polymerase tankyrase-2 Q9H2K2 TNKS2_HUMAN Homo sapiens 4 0.8644
Poly [ADP-ribose] polymerase tankyrase-2 Q9H2K2 TNKS2_HUMAN Homo sapiens 4 0.8644
Mitogen-activated protein kinase 14 Q16539 MK14_HUMAN Homo sapiens 3 0.8628
Mitogen-activated protein kinase 14 Q16539 MK14_HUMAN Homo sapiens 3 0.8628
Poly [ADP-ribose] polymerase tankyrase-2 Q9H2K2 TNKS2_HUMAN Homo sapiens 4 0.8617
Poly [ADP-ribose] polymerase tankyrase-2 Q9H2K2 TNKS2_HUMAN Homo sapiens 4 0.8617
Poly [ADP-ribose] polymerase tankyrase-2 Q9H2K2 TNKS2_HUMAN Homo sapiens 4 0.8576
Poly [ADP-ribose] polymerase tankyrase-2 Q9H2K2 TNKS2_HUMAN Homo sapiens 4 0.8576
Lactoperoxidase P80025 PERL_BOVIN Bos taurus 3 0.8572
Lactoperoxidase P80025 PERL_BOVIN Bos taurus 3 0.8572
Serine/threonine-protein kinase 10 O94804 STK10_HUMAN Homo sapiens 3 0.8555
Serine/threonine-protein kinase 10 O94804 STK10_HUMAN Homo sapiens 3 0.8555
Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase Q9TQS6 DHDH_MACFA Macaca fascicularis 3 0.8548
Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase Q9TQS6 DHDH_MACFA Macaca fascicularis 3 0.8548
Mycocyclosin synthase P9WPP7 CP121_MYCTU Mycobacterium tuberculosis 3 0.8542
Mycocyclosin synthase P9WPP7 CP121_MYCTU Mycobacterium tuberculosis 3 0.8542
DNA topoisomerase 4 subunit B H7C794 PARE_ENTFA Enterococcus faecalis 3 0.8518
DNA topoisomerase 4 subunit B H7C794 PARE_ENTFA Enterococcus faecalis 3 0.8518
Capsid protein Q9WBP8 Q9WBP8_9VIRU Adeno-associated virus - 1 3 0.8502
Capsid protein Q9WBP8 Q9WBP8_9VIRU Adeno-associated virus - 1 3 0.8502
Serine/threonine-protein kinase Chk1 O14757 CHK1_HUMAN Homo sapiens 4 0.8499
Serine/threonine-protein kinase Chk1 O14757 CHK1_HUMAN Homo sapiens 4 0.8499
Poly [ADP-ribose] polymerase tankyrase-2 Q9H2K2 TNKS2_HUMAN Homo sapiens 4 0.8466
Poly [ADP-ribose] polymerase tankyrase-2 Q9H2K2 TNKS2_HUMAN Homo sapiens 4 0.8466
Poly [ADP-ribose] polymerase 1 P09874 PARP1_HUMAN Homo sapiens 3 0.8446
Poly [ADP-ribose] polymerase 1 P09874 PARP1_HUMAN Homo sapiens 3 0.8446
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform O02697 PK3CG_PIG Sus scrofa 4 0.8444
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform O02697 PK3CG_PIG Sus scrofa 4 0.8444
Glycogen synthase kinase-3 beta P49841 GSK3B_HUMAN Homo sapiens 3 0.8441
Glycogen synthase kinase-3 beta P49841 GSK3B_HUMAN Homo sapiens 3 0.8441
BMP-2-inducible protein kinase Q9NSY1 BMP2K_HUMAN Homo sapiens 3 0.8414
BMP-2-inducible protein kinase Q9NSY1 BMP2K_HUMAN Homo sapiens 3 0.8414
Diphtheria toxin P00588 DTX_CORBE Corynephage beta 3 0.8394
Diphtheria toxin P00588 DTX_CORBE Corynephage beta 3 0.8394
Poly [ADP-ribose] polymerase tankyrase-2 Q9H2K2 TNKS2_HUMAN Homo sapiens 4 0.8392
Poly [ADP-ribose] polymerase tankyrase-2 Q9H2K2 TNKS2_HUMAN Homo sapiens 4 0.8392
Serine hydroxymethyltransferase Q7SIB6 Q7SIB6_GEOSE Geobacillus stearothermophilus 4 0.8385
Serine hydroxymethyltransferase Q7SIB6 Q7SIB6_GEOSE Geobacillus stearothermophilus 4 0.8385
Adenosine kinase Q9TVW2 ADK_TOXGO Toxoplasma gondii 4 0.8366
Adenosine kinase Q9TVW2 ADK_TOXGO Toxoplasma gondii 4 0.8366
Chitinase Q54276 Q54276_SERMA Serratia marcescens 3 0.8358
Chitinase Q54276 Q54276_SERMA Serratia marcescens 3 0.8358
Mitogen-activated protein kinase kinase kinase 5 Q99683 M3K5_HUMAN Homo sapiens 3 0.8355
Mitogen-activated protein kinase kinase kinase 5 Q99683 M3K5_HUMAN Homo sapiens 3 0.8355
Poly [ADP-ribose] polymerase tankyrase-2 Q9H2K2 TNKS2_HUMAN Homo sapiens 4 0.8350
Poly [ADP-ribose] polymerase tankyrase-2 Q9H2K2 TNKS2_HUMAN Homo sapiens 4 0.8350
Serine/threonine-protein kinase 24 Q9Y6E0 STK24_HUMAN Homo sapiens 3 0.8349
Serine/threonine-protein kinase 24 Q9Y6E0 STK24_HUMAN Homo sapiens 3 0.8349
17beta-hydroxysteroid dehydrogenase O93874 O93874_COCLU Cochliobolus lunatus 3 0.8338
17beta-hydroxysteroid dehydrogenase O93874 O93874_COCLU Cochliobolus lunatus 3 0.8338
Leucoanthocyanidin dioxygenase Q96323 LDOX_ARATH Arabidopsis thaliana 4 0.8335
Leucoanthocyanidin dioxygenase Q96323 LDOX_ARATH Arabidopsis thaliana 4 0.8335
Mycocyclosin synthase P9WPP7 CP121_MYCTU Mycobacterium tuberculosis 3 0.8318
Mycocyclosin synthase P9WPP7 CP121_MYCTU Mycobacterium tuberculosis 3 0.8318
Mitogen-activated protein kinase 14 Q16539 MK14_HUMAN Homo sapiens 3 0.8318
Mitogen-activated protein kinase 14 Q16539 MK14_HUMAN Homo sapiens 3 0.8318
Mitogen-activated protein kinase 14 Q16539 MK14_HUMAN Homo sapiens 3 0.8292
Mitogen-activated protein kinase 14 Q16539 MK14_HUMAN Homo sapiens 3 0.8292
Poly [ADP-ribose] polymerase tankyrase-2 Q9H2K2 TNKS2_HUMAN Homo sapiens 4 0.8291
Poly [ADP-ribose] polymerase tankyrase-2 Q9H2K2 TNKS2_HUMAN Homo sapiens 4 0.8291
Fibroblast growth factor receptor 1 P11362 FGFR1_HUMAN Homo sapiens 3 0.8265
Fibroblast growth factor receptor 1 P11362 FGFR1_HUMAN Homo sapiens 3 0.8265
Lactotransferrin P24627 TRFL_BOVIN Bos taurus 3 0.8245
Lactotransferrin P24627 TRFL_BOVIN Bos taurus 3 0.8245
ATP-dependent molecular chaperone HSP82 P02829 HSP82_YEAST Saccharomyces cerevisiae 3 0.8236
ATP-dependent molecular chaperone HSP82 P02829 HSP82_YEAST Saccharomyces cerevisiae 3 0.8236
Poly [ADP-ribose] polymerase 1 P09874 PARP1_HUMAN Homo sapiens 3 0.8215
Poly [ADP-ribose] polymerase 1 P09874 PARP1_HUMAN Homo sapiens 3 0.8215
Stromelysin-1 P08254 MMP3_HUMAN Homo sapiens 3 0.8156
Stromelysin-1 P08254 MMP3_HUMAN Homo sapiens 3 0.8156
Mitogen-activated protein kinase 14 Q16539 MK14_HUMAN Homo sapiens 3 0.8129
Mitogen-activated protein kinase 14 Q16539 MK14_HUMAN Homo sapiens 3 0.8129
Soluble cytochrome b562 P0ABE7 C562_ECOLX Escherichia coli 3 0.8102
Soluble cytochrome b562 P0ABE7 C562_ECOLX Escherichia coli 3 0.8102
Ribosomal protein S6 kinase alpha-3 P18654 KS6A3_MOUSE Mus musculus 5 0.8095
Ribosomal protein S6 kinase alpha-3 P18654 KS6A3_MOUSE Mus musculus 5 0.8095
Mitogen-activated protein kinase 1 P28482 MK01_HUMAN Homo sapiens 3 0.8090
Mitogen-activated protein kinase 1 P28482 MK01_HUMAN Homo sapiens 3 0.8090
Serine/threonine-protein kinase SKY1 Q03656 SKY1_YEAST Saccharomyces cerevisiae 3 0.8047
Serine/threonine-protein kinase SKY1 Q03656 SKY1_YEAST Saccharomyces cerevisiae 3 0.8047
Heat shock protein HSP 90-alpha P07900 HS90A_HUMAN Homo sapiens 3 0.8026
Heat shock protein HSP 90-alpha P07900 HS90A_HUMAN Homo sapiens 3 0.8026
Glycogen synthase kinase-3 beta P49841 GSK3B_HUMAN Homo sapiens 3 0.8005
Glycogen synthase kinase-3 beta P49841 GSK3B_HUMAN Homo sapiens 3 0.8005
ActVA 6 protein Q53908 Q53908_STRCH Streptomyces coelicolor 3 0.7981
ActVA 6 protein Q53908 Q53908_STRCH Streptomyces coelicolor 3 0.7981
5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase P0AF12 MTNN_ECOLI Escherichia coli 3 0.7969
5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase P0AF12 MTNN_ECOLI Escherichia coli 3 0.7969
Cyclin-dependent kinase 2 P24941 CDK2_HUMAN Homo sapiens 3 0.7966
Cyclin-dependent kinase 2 P24941 CDK2_HUMAN Homo sapiens 3 0.7966
Poly [ADP-ribose] polymerase tankyrase-2 Q9H2K2 TNKS2_HUMAN Homo sapiens 3 0.7960
Poly [ADP-ribose] polymerase tankyrase-2 Q9H2K2 TNKS2_HUMAN Homo sapiens 3 0.7960
Chalcone--flavanone isomerase 1 P28012 CFI1_MEDSA Medicago sativa 4 0.7958
Chalcone--flavanone isomerase 1 P28012 CFI1_MEDSA Medicago sativa 4 0.7958
Focal adhesion kinase 1 Q05397 FAK1_HUMAN Homo sapiens 4 0.7950
Focal adhesion kinase 1 Q05397 FAK1_HUMAN Homo sapiens 4 0.7950
Serine/threonine-protein kinase 24 Q9Y6E0 STK24_HUMAN Homo sapiens 3 0.7924
Serine/threonine-protein kinase 24 Q9Y6E0 STK24_HUMAN Homo sapiens 3 0.7924
Basic phospholipase A2 VRV-PL-VIIIa P59071 PA2B8_DABRR Daboia russelii 3 0.7917
Basic phospholipase A2 VRV-PL-VIIIa P59071 PA2B8_DABRR Daboia russelii 3 0.7917
Peroxisome proliferator-activated receptor gamma P37231 PPARG_HUMAN Homo sapiens 3 0.7911
Peroxisome proliferator-activated receptor gamma P37231 PPARG_HUMAN Homo sapiens 3 0.7911
Serine/threonine-protein kinase pim-1 P11309 PIM1_HUMAN Homo sapiens 4 0.7899
Serine/threonine-protein kinase pim-1 P11309 PIM1_HUMAN Homo sapiens 4 0.7899
4-diphosphocytidyl-2-C-methyl-D-erythritol kinase O67060 ISPE_AQUAE Aquifex aeolicus 3 0.7899
4-diphosphocytidyl-2-C-methyl-D-erythritol kinase O67060 ISPE_AQUAE Aquifex aeolicus 3 0.7899
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform O02697 PK3CG_PIG Sus scrofa 5 0.7890
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform O02697 PK3CG_PIG Sus scrofa 5 0.7890
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase Q8DNV6 Q8DNV6_STRR6 Streptococcus pneumoniae 3 0.7874
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase Q8DNV6 Q8DNV6_STRR6 Streptococcus pneumoniae 3 0.7874
Glycogen synthase kinase-3 beta P49841 GSK3B_HUMAN Homo sapiens 3 0.7845
Glycogen synthase kinase-3 beta P49841 GSK3B_HUMAN Homo sapiens 3 0.7845
Tyrosine-protein kinase JAK2 O60674 JAK2_HUMAN Homo sapiens 3 0.7837
Tyrosine-protein kinase JAK2 O60674 JAK2_HUMAN Homo sapiens 3 0.7837
Abscisic acid receptor PYL2 O80992 PYL2_ARATH Arabidopsis thaliana 3 0.7829
Abscisic acid receptor PYL2 O80992 PYL2_ARATH Arabidopsis thaliana 3 0.7829
Poly [ADP-ribose] polymerase tankyrase-2 Q9H2K2 TNKS2_HUMAN Homo sapiens 5 0.7828
Poly [ADP-ribose] polymerase tankyrase-2 Q9H2K2 TNKS2_HUMAN Homo sapiens 5 0.7828
Cyclin-dependent kinase 2 P24941 CDK2_HUMAN Homo sapiens 3 0.7827
Cyclin-dependent kinase 2 P24941 CDK2_HUMAN Homo sapiens 3 0.7827
Hypoxanthine phosphoribosyltransferase Q4DRC4 Q4DRC4_TRYCC Trypanosoma cruzi 3 0.7824
Hypoxanthine phosphoribosyltransferase Q4DRC4 Q4DRC4_TRYCC Trypanosoma cruzi 3 0.7824
Poly [ADP-ribose] polymerase tankyrase-2 Q9H2K2 TNKS2_HUMAN Homo sapiens 5 0.7822
Poly [ADP-ribose] polymerase tankyrase-2 Q9H2K2 TNKS2_HUMAN Homo sapiens 5 0.7822
Carbonic anhydrase 2 P00918 CAH2_HUMAN Homo sapiens 2 0.7796
Carbonic anhydrase 2 P00918 CAH2_HUMAN Homo sapiens 2 0.7796
Leucoanthocyanidin dioxygenase Q96323 LDOX_ARATH Arabidopsis thaliana 4 0.7794
Leucoanthocyanidin dioxygenase Q96323 LDOX_ARATH Arabidopsis thaliana 4 0.7794
Poly [ADP-ribose] polymerase tankyrase-2 Q9H2K2 TNKS2_HUMAN Homo sapiens 4 0.7772
Poly [ADP-ribose] polymerase tankyrase-2 Q9H2K2 TNKS2_HUMAN Homo sapiens 4 0.7772
Epidermal growth factor receptor P00533 EGFR_HUMAN Homo sapiens 3 0.7755
Epidermal growth factor receptor P00533 EGFR_HUMAN Homo sapiens 3 0.7755
APH(2'')-Id O68183 O68183_ENTCA Enterococcus casseliflavus 4 0.7748
APH(2'')-Id O68183 O68183_ENTCA Enterococcus casseliflavus 4 0.7748
17beta-hydroxysteroid dehydrogenase O93874 O93874_COCLU Cochliobolus lunatus 3 0.7740
17beta-hydroxysteroid dehydrogenase O93874 O93874_COCLU Cochliobolus lunatus 3 0.7740
Heat shock protein HSP 90-alpha P07900 HS90A_HUMAN Homo sapiens 3 0.7733
Heat shock protein HSP 90-alpha P07900 HS90A_HUMAN Homo sapiens 3 0.7733
Uracil phosphoribosyltransferase Q26998 UPP_TOXGO Toxoplasma gondii 3 0.7699
Uracil phosphoribosyltransferase Q26998 UPP_TOXGO Toxoplasma gondii 3 0.7699
Thymidylate synthase P00469 TYSY_LACCA Lacticaseibacillus casei 3 0.7698
Thymidylate synthase P00469 TYSY_LACCA Lacticaseibacillus casei 3 0.7698
Bromodomain-containing protein 2 P25440 BRD2_HUMAN Homo sapiens 4 0.7683
Bromodomain-containing protein 2 P25440 BRD2_HUMAN Homo sapiens 4 0.7683
Glycogen synthase Q9V2J8 Q9V2J8_PYRAB Pyrococcus abyssi 3 0.7673
Glycogen synthase Q9V2J8 Q9V2J8_PYRAB Pyrococcus abyssi 3 0.7673
Cyclin-dependent kinase 9 P50750 CDK9_HUMAN Homo sapiens 3 0.7645
Cyclin-dependent kinase 9 P50750 CDK9_HUMAN Homo sapiens 3 0.7645
Basic phospholipase A2 VRV-PL-VIIIa P59071 PA2B8_DABRR Daboia russelii 2 0.7642
Basic phospholipase A2 VRV-PL-VIIIa P59071 PA2B8_DABRR Daboia russelii 2 0.7642
Mycocyclosin synthase P9WPP7 CP121_MYCTU Mycobacterium tuberculosis 3 0.7636
Mycocyclosin synthase P9WPP7 CP121_MYCTU Mycobacterium tuberculosis 3 0.7636
Cytohesin-2 Q99418 CYH2_HUMAN Homo sapiens 4 0.7632
Cytohesin-2 Q99418 CYH2_HUMAN Homo sapiens 4 0.7632
Ribonuclease J H9CZL7 H9CZL7_DEIRD Deinococcus radiodurans 3 0.7622
Ribonuclease J H9CZL7 H9CZL7_DEIRD Deinococcus radiodurans 3 0.7622
Genome polyprotein O92972 POLG_HCVJ4 Hepatitis C virus genotype 1b 3 0.7611
Genome polyprotein O92972 POLG_HCVJ4 Hepatitis C virus genotype 1b 3 0.7611
Chymotrypsinogen A P00766 CTRA_BOVIN Bos taurus 3 0.7587
Chymotrypsinogen A P00766 CTRA_BOVIN Bos taurus 3 0.7587
11-beta-hydroxysteroid dehydrogenase 1 P28845 DHI1_HUMAN Homo sapiens 3 0.7579
11-beta-hydroxysteroid dehydrogenase 1 P28845 DHI1_HUMAN Homo sapiens 3 0.7579
Prothrombin P00734 THRB_HUMAN Homo sapiens 3 0.7572
Prothrombin P00734 THRB_HUMAN Homo sapiens 3 0.7572
Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplastic Q43088 RBCMT_PEA Pisum sativum 3 0.7553
Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplastic Q43088 RBCMT_PEA Pisum sativum 3 0.7553
Nuclear receptor subfamily 4immunitygroup A member 1 P22736 NR4A1_HUMAN Homo sapiens 3 0.7538
Nuclear receptor subfamily 4immunitygroup A member 1 P22736 NR4A1_HUMAN Homo sapiens 3 0.7538
O-methyltransferase family 2 D5STZ7 D5STZ7_PLAL2 Planctopirus limnophila 4 0.7526
O-methyltransferase family 2 D5STZ7 D5STZ7_PLAL2 Planctopirus limnophila 4 0.7526
Poly [ADP-ribose] polymerase tankyrase-2 Q9H2K2 TNKS2_HUMAN Homo sapiens 3 0.7522
Poly [ADP-ribose] polymerase tankyrase-2 Q9H2K2 TNKS2_HUMAN Homo sapiens 3 0.7522
Bromodomain-containing protein 4 O60885 BRD4_HUMAN Homo sapiens 4 0.7518
Bromodomain-containing protein 4 O60885 BRD4_HUMAN Homo sapiens 4 0.7518
3',5'-cyclic-AMP phosphodiesterase 4D Q08499 PDE4D_HUMAN Homo sapiens 3 0.7515
3',5'-cyclic-AMP phosphodiesterase 4D Q08499 PDE4D_HUMAN Homo sapiens 3 0.7515
Thymidylate synthase P0A886 TYSY_ECO57 Escherichia coli O157:H7 3 0.7514
Thymidylate synthase P0A886 TYSY_ECO57 Escherichia coli O157:H7 3 0.7514
Gag-Pol polyprotein P04585 POL_HV1H2 Human immunodeficiency virus type 1 group M subtype B 3 0.7511
Gag-Pol polyprotein P04585 POL_HV1H2 Human immunodeficiency virus type 1 group M subtype B 3 0.7511
Heat shock protein HSP 90-beta P08238 HS90B_HUMAN Homo sapiens 3 0.7487
Heat shock protein HSP 90-beta P08238 HS90B_HUMAN Homo sapiens 3 0.7487
Bromodomain-containing protein 2 P25440 BRD2_HUMAN Homo sapiens 4 0.7485
Bromodomain-containing protein 2 P25440 BRD2_HUMAN Homo sapiens 4 0.7485
Pyruvate kinase PKM P14618 KPYM_HUMAN Homo sapiens 3 0.7471
Pyruvate kinase PKM P14618 KPYM_HUMAN Homo sapiens 3 0.7471
Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplastic Q43088 RBCMT_PEA Pisum sativum 3 0.7468
Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplastic Q43088 RBCMT_PEA Pisum sativum 3 0.7468
Chalcone--flavanone isomerase 1 P28012 CFI1_MEDSA Medicago sativa 4 0.7461
Chalcone--flavanone isomerase 1 P28012 CFI1_MEDSA Medicago sativa 4 0.7461
3-hydroxyisobutyryl-CoA hydrolase, mitochondrial Q6NVY1 HIBCH_HUMAN Homo sapiens 3 0.7460
3-hydroxyisobutyryl-CoA hydrolase, mitochondrial Q6NVY1 HIBCH_HUMAN Homo sapiens 3 0.7460
Serine/threonine-protein kinase pim-1 P11309 PIM1_HUMAN Homo sapiens 4 0.7458
Serine/threonine-protein kinase pim-1 P11309 PIM1_HUMAN Homo sapiens 4 0.7458
Poly [ADP-ribose] polymerase 1 P09874 PARP1_HUMAN Homo sapiens 3 0.7439
Glutathione S-transferase F2 P46422 GSTF2_ARATH Arabidopsis thaliana 3 0.7439
Poly [ADP-ribose] polymerase 1 P09874 PARP1_HUMAN Homo sapiens 3 0.7439
Glutathione S-transferase F2 P46422 GSTF2_ARATH Arabidopsis thaliana 3 0.7439
Basic phospholipase A2 VRV-PL-VIIIa P59071 PA2B8_DABRR Daboia russelii 3 0.7429
Basic phospholipase A2 VRV-PL-VIIIa P59071 PA2B8_DABRR Daboia russelii 3 0.7429
Single-strand selective monofunctional uracil DNA glycosylase Q9YGN6 SMUG1_XENLA Xenopus laevis 4 0.7402
Single-strand selective monofunctional uracil DNA glycosylase Q9YGN6 SMUG1_XENLA Xenopus laevis 4 0.7402
Aminoglycoside 3'-phosphotransferase AphA1-IAB B0VD92 B0VD92_ACIBY Acinetobacter baumannii 3 0.7394
Aminoglycoside 3'-phosphotransferase AphA1-IAB B0VD92 B0VD92_ACIBY Acinetobacter baumannii 3 0.7394
Tyrosine-protein kinase JAK1 P23458 JAK1_HUMAN Homo sapiens 4 0.7386
Tyrosine-protein kinase JAK1 P23458 JAK1_HUMAN Homo sapiens 4 0.7386
Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplastic Q43088 RBCMT_PEA Pisum sativum 3 0.7382
Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplastic Q43088 RBCMT_PEA Pisum sativum 3 0.7382
Carbonic anhydrase 2 P00918 CAH2_HUMAN Homo sapiens 3 0.7381
Carbonic anhydrase 2 P00918 CAH2_HUMAN Homo sapiens 3 0.7381
Vascular endothelial growth factor receptor 2 P35968 VGFR2_HUMAN Homo sapiens 3 0.7376
Vascular endothelial growth factor receptor 2 P35968 VGFR2_HUMAN Homo sapiens 3 0.7376
Poly [ADP-ribose] polymerase tankyrase-2 Q9H2K2 TNKS2_HUMAN Homo sapiens 4 0.7375
Poly [ADP-ribose] polymerase tankyrase-2 Q9H2K2 TNKS2_HUMAN Homo sapiens 4 0.7375
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform P48736 PK3CG_HUMAN Homo sapiens 3 0.7370
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform P48736 PK3CG_HUMAN Homo sapiens 3 0.7370
Histone-lysine N-methyltransferase SETD7 Q8WTS6 SETD7_HUMAN Homo sapiens 3 0.7363
Histone-lysine N-methyltransferase SETD7 Q8WTS6 SETD7_HUMAN Homo sapiens 3 0.7363
Glycogen synthase kinase-3 beta P49841 GSK3B_HUMAN Homo sapiens 3 0.7357
Glycogen synthase kinase-3 beta P49841 GSK3B_HUMAN Homo sapiens 3 0.7357
Poly [ADP-ribose] polymerase tankyrase-2 Q9H2K2 TNKS2_HUMAN Homo sapiens 4 0.7340
Poly [ADP-ribose] polymerase tankyrase-2 Q9H2K2 TNKS2_HUMAN Homo sapiens 4 0.7340
Ribosyldihydronicotinamide dehydrogenase [quinone] P16083 NQO2_HUMAN Homo sapiens 3 0.7334
Poly [ADP-ribose] polymerase tankyrase-2 Q9H2K2 TNKS2_HUMAN Homo sapiens 4 0.7334
Poly [ADP-ribose] polymerase tankyrase-2 Q9H2K2 TNKS2_HUMAN Homo sapiens 4 0.7334
Ribosyldihydronicotinamide dehydrogenase [quinone] P16083 NQO2_HUMAN Homo sapiens 3 0.7334
Protein ppBat Q8A8A4 Q8A8A4_BACTN Bacteroides thetaiotaomicron VPI-5482 3 0.7327
Protein ppBat Q8A8A4 Q8A8A4_BACTN Bacteroides thetaiotaomicron VPI-5482 3 0.7327
Glycogen synthase kinase-3 beta P49841 GSK3B_HUMAN Homo sapiens 3 0.7326
Glycogen synthase kinase-3 beta P49841 GSK3B_HUMAN Homo sapiens 3 0.7326
Lactotransferrin P24627 TRFL_BOVIN Bos taurus 2 0.7322
Lactotransferrin P24627 TRFL_BOVIN Bos taurus 2 0.7322
Dihydrofolate reductase P0A017 DYR_STAAU Staphylococcus aureus 3 0.7321
Dihydrofolate reductase P0A017 DYR_STAAU Staphylococcus aureus 3 0.7321
Major strawberry allergen Fra a 1-3 D0E0C7 FRA13_FRAAN Fragaria ananassa 4 0.7318
Major strawberry allergen Fra a 1-3 D0E0C7 FRA13_FRAAN Fragaria ananassa 4 0.7318
Endothiapepsin P11838 CARP_CRYPA Cryphonectria parasitica 3 0.7313
Endothiapepsin P11838 CARP_CRYPA Cryphonectria parasitica 3 0.7313
Large structural protein Q91L20 Q91L20_9MONO Human metapneumovirus 3 0.7312
Large structural protein Q91L20 Q91L20_9MONO Human metapneumovirus 3 0.7312
Bromodomain-containing protein 4 O60885 BRD4_HUMAN Homo sapiens 4 0.7304
Death-associated protein kinase 1 P53355 DAPK1_HUMAN Homo sapiens 3 0.7304
Bromodomain-containing protein 4 O60885 BRD4_HUMAN Homo sapiens 4 0.7304
Death-associated protein kinase 1 P53355 DAPK1_HUMAN Homo sapiens 3 0.7304
Heat shock protein HSP 90-alpha P07900 HS90A_HUMAN Homo sapiens 2 0.7291
Heat shock protein HSP 90-alpha P07900 HS90A_HUMAN Homo sapiens 2 0.7291
L-lactate dehydrogenase A chain P13491 LDHA_RABIT Oryctolagus cuniculus 2 0.7288
L-lactate dehydrogenase A chain P13491 LDHA_RABIT Oryctolagus cuniculus 2 0.7288
Poly [ADP-ribose] polymerase tankyrase-2 Q9H2K2 TNKS2_HUMAN Homo sapiens 4 0.7283
Poly [ADP-ribose] polymerase tankyrase-2 Q9H2K2 TNKS2_HUMAN Homo sapiens 4 0.7283
Protein mono-ADP-ribosyltransferase PARP3 Q9Y6F1 PARP3_HUMAN Homo sapiens 3 0.7280
Protein mono-ADP-ribosyltransferase PARP3 Q9Y6F1 PARP3_HUMAN Homo sapiens 3 0.7280
Protein mono-ADP-ribosyltransferase PARP15 Q460N3 PAR15_HUMAN Homo sapiens 3 0.7269
Protein mono-ADP-ribosyltransferase PARP15 Q460N3 PAR15_HUMAN Homo sapiens 3 0.7269
Glycogen synthase Q9V2J8 Q9V2J8_PYRAB Pyrococcus abyssi 3 0.7260
Glycogen synthase Q9V2J8 Q9V2J8_PYRAB Pyrococcus abyssi 3 0.7260
Casein kinase II subunit alpha P68400 CSK21_HUMAN Homo sapiens 3 0.7250
Casein kinase II subunit alpha P68400 CSK21_HUMAN Homo sapiens 3 0.7250
Quercetin 2,3-dioxygenase Q7SIC2 QDOI_ASPJA Aspergillus japonicus 4 0.7250
Quercetin 2,3-dioxygenase Q7SIC2 QDOI_ASPJA Aspergillus japonicus 4 0.7250
3',5'-cyclic-AMP phosphodiesterase 4B Q07343 PDE4B_HUMAN Homo sapiens 3 0.7246
3',5'-cyclic-AMP phosphodiesterase 4B Q07343 PDE4B_HUMAN Homo sapiens 3 0.7246
Nitric oxide synthase, inducible P29477 NOS2_MOUSE Mus musculus 3 0.7229
Nitric oxide synthase, inducible P29477 NOS2_MOUSE Mus musculus 3 0.7229
Tyrosine-protein kinase JAK3 P52333 JAK3_HUMAN Homo sapiens 4 0.7223
Tyrosine-protein kinase JAK3 P52333 JAK3_HUMAN Homo sapiens 4 0.7223
Poly [ADP-ribose] polymerase tankyrase-2 Q9H2K2 TNKS2_HUMAN Homo sapiens 4 0.7190
Poly [ADP-ribose] polymerase tankyrase-2 Q9H2K2 TNKS2_HUMAN Homo sapiens 4 0.7190
Histone-lysine N-methyltransferase 2C Q8NEZ4 KMT2C_HUMAN Homo sapiens 3 0.7187
Histone-lysine N-methyltransferase 2C Q8NEZ4 KMT2C_HUMAN Homo sapiens 3 0.7187
Endothiapepsin P11838 CARP_CRYPA Cryphonectria parasitica 3 0.7181
Endothiapepsin P11838 CARP_CRYPA Cryphonectria parasitica 3 0.7181
Carbonic anhydrase 2 P00918 CAH2_HUMAN Homo sapiens 3 0.7158
Carbonic anhydrase 2 P00918 CAH2_HUMAN Homo sapiens 3 0.7158
Prothrombin P00734 THRB_HUMAN Homo sapiens 3 0.7154
Chalcone--flavanone isomerase 1 P28012 CFI1_MEDSA Medicago sativa 3 0.7154
Prothrombin P00734 THRB_HUMAN Homo sapiens 3 0.7154
Chalcone--flavanone isomerase 1 P28012 CFI1_MEDSA Medicago sativa 3 0.7154
Peripheral plasma membrane protein CASK O14936 CSKP_HUMAN Homo sapiens 3 0.7150
Peripheral plasma membrane protein CASK O14936 CSKP_HUMAN Homo sapiens 3 0.7150
Glucan 1,3-beta-glucosidase P29717 EXG1_CANAL Candida albicans 2 0.7142
Glucan 1,3-beta-glucosidase P29717 EXG1_CANAL Candida albicans 2 0.7142
Poly [ADP-ribose] polymerase tankyrase-2 Q9H2K2 TNKS2_HUMAN Homo sapiens 4 0.7137
Poly [ADP-ribose] polymerase tankyrase-2 Q9H2K2 TNKS2_HUMAN Homo sapiens 4 0.7137
Estrogen receptor beta Q92731 ESR2_HUMAN Homo sapiens 4 0.7135
Estrogen receptor beta Q92731 ESR2_HUMAN Homo sapiens 4 0.7135
Poly [ADP-ribose] polymerase 1 P09874 PARP1_HUMAN Homo sapiens 3 0.7129
Poly [ADP-ribose] polymerase 1 P09874 PARP1_HUMAN Homo sapiens 3 0.7129
Beta-glucosidase 1A Q25BW5 BGL1A_PHACH Phanerodontia chrysosporium 3 0.7124
Beta-glucosidase 1A Q25BW5 BGL1A_PHACH Phanerodontia chrysosporium 3 0.7124
Ribosomal small subunit pseudouridine synthase A P0AA43 RSUA_ECOLI Escherichia coli 3 0.7113
Ribosomal small subunit pseudouridine synthase A P0AA43 RSUA_ECOLI Escherichia coli 3 0.7113
Mitogen-activated protein kinase 14 Q16539 MK14_HUMAN Homo sapiens 3 0.7108
Dihydrofolate reductase P0A017 DYR_STAAU Staphylococcus aureus 3 0.7108
Dihydrofolate reductase P0A017 DYR_STAAU Staphylococcus aureus 3 0.7108
Mitogen-activated protein kinase 14 Q16539 MK14_HUMAN Homo sapiens 3 0.7108
Serine/threonine-protein kinase PLK1 P53350 PLK1_HUMAN Homo sapiens 3 0.7105
Serine/threonine-protein kinase PLK1 P53350 PLK1_HUMAN Homo sapiens 3 0.7105
Histone-lysine N-methyltransferase EHMT1 Q9H9B1 EHMT1_HUMAN Homo sapiens 3 0.7099
Histone-lysine N-methyltransferase EHMT1 Q9H9B1 EHMT1_HUMAN Homo sapiens 3 0.7099
Metallo-beta-lactamase type 2 P25910 BLAB_BACFG Bacteroides fragilis 3 0.7096
Metallo-beta-lactamase type 2 P25910 BLAB_BACFG Bacteroides fragilis 3 0.7096
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform P48736 PK3CG_HUMAN Homo sapiens 3 0.7093
Aklavinone 12-hydroxylase RdmE Q54530 DNRF_STREF Streptomyces purpurascens 4 0.7093
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform P48736 PK3CG_HUMAN Homo sapiens 3 0.7093
Aklavinone 12-hydroxylase RdmE Q54530 DNRF_STREF Streptomyces purpurascens 4 0.7093
Histone-lysine N-methyltransferase EHMT2 Q96KQ7 EHMT2_HUMAN Homo sapiens 3 0.7091
Histone-lysine N-methyltransferase EHMT2 Q96KQ7 EHMT2_HUMAN Homo sapiens 3 0.7091
Chalcone--flavanone isomerase 1 P28012 CFI1_MEDSA Medicago sativa 3 0.7089
Chalcone--flavanone isomerase 1 P28012 CFI1_MEDSA Medicago sativa 3 0.7089
Poly [ADP-ribose] polymerase tankyrase-2 Q9H2K2 TNKS2_HUMAN Homo sapiens 4 0.7086
Poly [ADP-ribose] polymerase tankyrase-2 Q9H2K2 TNKS2_HUMAN Homo sapiens 4 0.7086
Multidrug transporter MdfA P0AEY8 MDFA_ECOLI Escherichia coli 3 0.7080
Multidrug transporter MdfA P0AEY8 MDFA_ECOLI Escherichia coli 3 0.7080
Glucose-1-phosphate thymidylyltransferase Q9HU22 Q9HU22_PSEAE Pseudomonas aeruginosa 3 0.7078
Glucose-1-phosphate thymidylyltransferase Q9HU22 Q9HU22_PSEAE Pseudomonas aeruginosa 3 0.7078
Poly [ADP-ribose] polymerase tankyrase-2 Q9H2K2 TNKS2_HUMAN Homo sapiens 4 0.7064
Poly [ADP-ribose] polymerase tankyrase-2 Q9H2K2 TNKS2_HUMAN Homo sapiens 4 0.7064
Chalcone--flavanone isomerase 1 P28012 CFI1_MEDSA Medicago sativa 3 0.7061
Chalcone--flavanone isomerase 1 P28012 CFI1_MEDSA Medicago sativa 3 0.7061
Secoisolariciresinol dehydrogenase Q94KL8 SILD_PODPE Podophyllum peltatum 3 0.7042
Secoisolariciresinol dehydrogenase Q94KL8 SILD_PODPE Podophyllum peltatum 3 0.7042
Thymidylate synthase P04818 TYSY_HUMAN Homo sapiens 4 0.7040
Thymidylate synthase P04818 TYSY_HUMAN Homo sapiens 4 0.7040
Dihydrofolate reductase P00374 DYR_HUMAN Homo sapiens 3 0.7035
Dihydrofolate reductase P00374 DYR_HUMAN Homo sapiens 3 0.7035
Histone-lysine N-methyltransferase 2A Q03164 KMT2A_HUMAN Homo sapiens 3 0.7029
Histone-lysine N-methyltransferase 2A Q03164 KMT2A_HUMAN Homo sapiens 3 0.7029
Pentalenic acid synthase Q825I8 CYP28_STRAW Streptomyces avermitilis 2 0.7027
Pentalenic acid synthase Q825I8 CYP28_STRAW Streptomyces avermitilis 2 0.7027
Cyclin-dependent kinase 2 P24941 CDK2_HUMAN Homo sapiens 4 0.7026
Cyclin-dependent kinase 2 P24941 CDK2_HUMAN Homo sapiens 4 0.7026
Poly [ADP-ribose] polymerase tankyrase-2 Q9H2K2 TNKS2_HUMAN Homo sapiens 4 0.7018
Poly [ADP-ribose] polymerase tankyrase-2 Q9H2K2 TNKS2_HUMAN Homo sapiens 4 0.7018
Poly [ADP-ribose] polymerase tankyrase-2 Q9H2K2 TNKS2_HUMAN Homo sapiens 5 0.7016
Flavin-dependent thymidylate synthase Q9WYT0 THYX_THEMA Thermotoga maritima 3 0.7016
Flavin-dependent thymidylate synthase Q9WYT0 THYX_THEMA Thermotoga maritima 3 0.7016
Poly [ADP-ribose] polymerase tankyrase-2 Q9H2K2 TNKS2_HUMAN Homo sapiens 5 0.7016
dTDP-4-dehydro-6-deoxyglucose 3-epimerase Q5SFD1 CHMJ_STRBI Streptomyces bikiniensis 3 0.7015
dTDP-4-dehydro-6-deoxyglucose 3-epimerase Q5SFD1 CHMJ_STRBI Streptomyces bikiniensis 3 0.7015
dTDP-4-dehydrorhamnose 3,5-epimerase A0A6L7H6N0 A0A1S0QLH9_BACAN Bacillus anthracis 3 0.7012
dTDP-4-dehydrorhamnose 3,5-epimerase A0A6L7H6N0 A0A1S0QLH9_BACAN Bacillus anthracis 3 0.7012
Abscisic acid receptor PYR1 O49686 PYR1_ARATH Arabidopsis thaliana 3 0.7011
Abscisic acid receptor PYR1 O49686 PYR1_ARATH Arabidopsis thaliana 3 0.7011
Death-associated protein kinase 1 P53355 DAPK1_HUMAN Homo sapiens 3 0.7005
Death-associated protein kinase 1 P53355 DAPK1_HUMAN Homo sapiens 3 0.7005
Soluble acetylcholine receptor Q8WSF8 Q8WSF8_APLCA Aplysia californica 2 0.7001
Soluble acetylcholine receptor Q8WSF8 Q8WSF8_APLCA Aplysia californica 2 0.7001
MAP kinase-activated protein kinase 2 P49137 MAPK2_HUMAN Homo sapiens 3 0.7000
MAP kinase-activated protein kinase 2 P49137 MAPK2_HUMAN Homo sapiens 3 0.7000

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