Methyl phloroglucinol iV - Compound Card

Methyl phloroglucinol iV

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Methyl phloroglucinol iV

Structure
Zoomed Structure
  • Family: Plantae - Rosaceae
  • Kingdom: Plantae
  • Class: Phenolic
Canonical Smiles CC(CC(=O)c1c(O)cc(c(c1O)C)O)C
InChI InChI=1S/C12H16O4/c1-6(2)4-9(14)11-10(15)5-8(13)7(3)12(11)16/h5-6,13,15-16H,4H2,1-3H3
InChIKey AQGJJVVGIDQMHX-UHFFFAOYSA-N
Formula C12H16O4
HBA 4
HBD 3
MW 224.26
Rotatable Bonds 3
TPSA 77.76
LogP 2.34
Number Rings 1
Number Aromatic Rings 1
Heavy Atom Count 16
Formal Charge 0
Fraction CSP3 0.42
Exact Mass 224.1
Number of Lipinski Rule Violations 0
# Species Family Kingdom NCBI Taxonomy ID
1 Hagenia abyssinica Rosaceae Plantae 57921

Showing of synonyms

  • Gemech M, Dagne E. (2007). Chemical study of anti-termite extract of saw dust of Hagenia abyssinica. M.Sc. Thesis-4, Addis Ababa University, Ethiopia, 2007. [View] [PubMed]
Pubchem: 597639

No compound-protein relationship available.

Structure

SMILES: c1ccccc1

Level: 0

Mol. Weight: 224.26 g/mol

No bioactivities available.

Absorption

Caco-2 (logPapp)
-4.61
Human Oral Bioavailability 20%
Bioavailable
Human Intestinal Absorption
Absorbed
Madin-Darby Canine Kidney
-4.77
Human Oral Bioavailability 50%
Bioavailable
P-Glycoprotein Inhibitor
Non-Inhibitor
P-Glycoprotein Substrate
Non-Substrate
Skin Permeability
-1.54

Distribution

Blood-Brain Barrier (CNS)
-
Blood-Brain Barrier
Penetrable
Fraction Unbound (Human)
0.55
Plasma Protein Binding
37.74
Steady State Volume of Distribution
-

Metabolism

Breast Cancer Resistance Protein
Non-Inhibitor
CYP 1A2 Inhibitor
Inhibitor
CYP 1A2 Substrate
Substrate
CYP 2C19 Inhibitor
Inhibitor
CYP 2C19 Substrate
Substrate
CYP 2C9 Inhibitor
Non-Inhibitor
CYP 2C9 Substrate
Substrate
CYP 2D6 Inhibitor
Non-Inhibitor
CYP 2D6 Substrate
Non-Substrate
CYP 3A4 Inhibitor
Inhibitor
CYP 3A4 Substrate
Non-Substrate
OATP1B1
Non-Inhibitor
OATP1B3
Non-Inhibitor

Excretion

Clearance
13.82
Organic Cation Transporter 2
Non-Inhibitor
Half-Life of Drug
-

Toxicity

AMES Mutagenesis
Safe
Avian
Safe
Bee
Toxic
Bioconcentration Factor
0.5
Biodegradation
Safe
Carcinogenesis
Safe
Crustacean
Safe
Liver Injury I (DILI)
Safe
Eye Corrosion
Safe
Eye Irritation
Toxic
Maximum Tolerated Dose
-0.11
Liver Injury II
Safe
hERG Blockers
Safe
Daphnia Maga
4.86
Micronucleos
Toxic
NR-AhR
Safe
NR-AR
Safe
NR-AR-LBD
Safe
NR-Aromatase
Safe
NR-ER
Safe
NR-ER-LBD
Safe
NR-GR
Safe
NR-PPAR-gamma
Safe
NR-TR
Safe
T. Pyriformis
4.11
Rat (Acute)
2.21
Rat (Chronic Oral)
2.92
Fathead Minnow
4.03
Respiratory Disease
Toxic
Skin Sensitisation
Toxic
SR-ARE
Safe
SR-ATAD5
Safe
SR-HSE
Safe
SR-MMP
Toxic
SR-p53
Safe

General Properties

Boiling Point
335.25
Hydration Free Energy
-10.71
Log(D) at pH=7.4
2.05
Log(P)
3.81
Log S
-3.02
Log(Vapor Pressure)
-4.56
Melting Point
125.9
pKa Acid
5.64
pKa Basic
8.11
Protein Name UniProt ID Entry Name Species #Pharmacophore Points Probability (0.7 ≤ Tversky Score ≤ 1.0)
3',5'-cyclic-AMP phosphodiesterase 4D Q08499 PDE4D_HUMAN Homo sapiens 3 0.9071
3',5'-cyclic-AMP phosphodiesterase 4D Q08499 PDE4D_HUMAN Homo sapiens 3 0.9071
HTH-type transcriptional repressor PurR P0ACP7 PURR_ECOLI Escherichia coli 3 0.8830
HTH-type transcriptional repressor PurR P0ACP7 PURR_ECOLI Escherichia coli 3 0.8830
Steroid Delta-isomerase P07445 SDIS_PSEPU Pseudomonas putida 3 0.8763
Steroid Delta-isomerase P07445 SDIS_PSEPU Pseudomonas putida 3 0.8763
Steroid C26-monooxygenase P9WPP1 CP125_MYCTU Mycobacterium tuberculosis 3 0.8736
Steroid C26-monooxygenase P9WPP1 CP125_MYCTU Mycobacterium tuberculosis 3 0.8736
Toxoflavin degrading enzyme E3SET7 E3SET7_PAEPO Paenibacillus polymyxa 3 0.8719
Toxoflavin degrading enzyme E3SET7 E3SET7_PAEPO Paenibacillus polymyxa 3 0.8719
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 P04191 AT2A1_RABIT Oryctolagus cuniculus 3 0.8453
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 P04191 AT2A1_RABIT Oryctolagus cuniculus 3 0.8453
Steroid Delta-isomerase P00947 SDIS_COMTE Comamonas testosteroni 3 0.8404
Steroid Delta-isomerase P00947 SDIS_COMTE Comamonas testosteroni 3 0.8404
Sulfide-quinone reductase B7JBP8 SQRD_ACIF2 Acidithiobacillus ferrooxidans) 3 0.8361
Sulfide-quinone reductase B7JBP8 SQRD_ACIF2 Acidithiobacillus ferrooxidans) 3 0.8361
Flavoredoxin Q72HI0 Q72HI0_THET2 Thermus thermophilus 3 0.8339
Flavoredoxin Q72HI0 Q72HI0_THET2 Thermus thermophilus 3 0.8339
Achbp I6L8L2 I6L8L2_CAPTE Capitella teleta 3 0.8325
Achbp I6L8L2 I6L8L2_CAPTE Capitella teleta 3 0.8325
Pteridine reductase, putative Q581W1 Q581W1_TRYB2 Trypanosoma brucei brucei 4 0.8231
Pteridine reductase, putative Q581W1 Q581W1_TRYB2 Trypanosoma brucei brucei 4 0.8231
Carbonic anhydrase 2 P00918 CAH2_HUMAN Homo sapiens 3 0.8221
Carbonic anhydrase 2 P00918 CAH2_HUMAN Homo sapiens 3 0.8221
Succinate dehydrogenase flavoprotein subunit P0AC41 SDHA_ECOLI Escherichia coli 3 0.8149
Succinate dehydrogenase flavoprotein subunit P0AC41 SDHA_ECOLI Escherichia coli 3 0.8149
Ribosomal small subunit pseudouridine synthase A P0AA43 RSUA_ECOLI Escherichia coli 3 0.8126
Ribosomal small subunit pseudouridine synthase A P0AA43 RSUA_ECOLI Escherichia coli 3 0.8126
Succinate dehydrogenase flavoprotein subunit P0AC41 SDHA_ECOLI Escherichia coli 3 0.8099
Succinate dehydrogenase flavoprotein subunit P0AC41 SDHA_ECOLI Escherichia coli 3 0.8099
Heat shock protein HSP 90-alpha P07900 HS90A_HUMAN Homo sapiens 3 0.8089
Heat shock protein HSP 90-alpha P07900 HS90A_HUMAN Homo sapiens 3 0.8089
Soluble acetylcholine receptor Q8WSF8 Q8WSF8_APLCA Aplysia californica 3 0.8071
Soluble acetylcholine receptor Q8WSF8 Q8WSF8_APLCA Aplysia californica 3 0.8071
ActVA 6 protein Q53908 Q53908_STRCH Streptomyces coelicolor 3 0.8066
ActVA 6 protein Q53908 Q53908_STRCH Streptomyces coelicolor 3 0.8066
Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase F6MZ55 F6MZ55_9FIRM Sporomusa ovata 3 0.8063
Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase F6MZ55 F6MZ55_9FIRM Sporomusa ovata 3 0.8063
Heat shock protein HSP 90-alpha P07900 HS90A_HUMAN Homo sapiens 3 0.8054
Heat shock protein HSP 90-alpha P07900 HS90A_HUMAN Homo sapiens 3 0.8054
Purine nucleoside phosphorylase DeoD-type P0ABP8 DEOD_ECOLI Escherichia coli 3 0.8048
Purine nucleoside phosphorylase DeoD-type P0ABP8 DEOD_ECOLI Escherichia coli 3 0.8048
Serine/threonine-protein kinase Chk2 O96017 CHK2_HUMAN Homo sapiens 3 0.8034
Serine/threonine-protein kinase Chk2 O96017 CHK2_HUMAN Homo sapiens 3 0.8034
Aldo-keto reductase family 1 member D1 P51857 AK1D1_HUMAN Homo sapiens 3 0.7999
Aldo-keto reductase family 1 member D1 P51857 AK1D1_HUMAN Homo sapiens 3 0.7999
Aldo-keto reductase family 1 member D1 P51857 AK1D1_HUMAN Homo sapiens 3 0.7943
Aldo-keto reductase family 1 member D1 P51857 AK1D1_HUMAN Homo sapiens 3 0.7943
Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial Q0QF01 SDHA_PIG Sus scrofa 3 0.7933
Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial Q0QF01 SDHA_PIG Sus scrofa 3 0.7933
Soluble cytochrome b562 P0ABE7 C562_ECOLX Escherichia coli 3 0.7924
Soluble cytochrome b562 P0ABE7 C562_ECOLX Escherichia coli 3 0.7924
ATP-dependent molecular chaperone HSP82 P02829 HSP82_YEAST Saccharomyces cerevisiae 3 0.7904
ATP-dependent molecular chaperone HSP82 P02829 HSP82_YEAST Saccharomyces cerevisiae 3 0.7904
Fibroblast growth factor receptor 1 P11362 FGFR1_HUMAN Homo sapiens 3 0.7902
Fibroblast growth factor receptor 1 P11362 FGFR1_HUMAN Homo sapiens 3 0.7902
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 P04191 AT2A1_RABIT Oryctolagus cuniculus 4 0.7895
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 P04191 AT2A1_RABIT Oryctolagus cuniculus 4 0.7895
Proton-gated ion channel Q7NDN8 GLIC_GLOVI Gloeobacter violaceus 3 0.7887
Proton-gated ion channel Q7NDN8 GLIC_GLOVI Gloeobacter violaceus 3 0.7887
Glutamate receptor 2 P19491 GRIA2_RAT Rattus norvegicus 3 0.7879
Glutamate receptor 2 P19491 GRIA2_RAT Rattus norvegicus 3 0.7879
Carbonic anhydrase 2 P00918 CAH2_HUMAN Homo sapiens 2 0.7863
Carbonic anhydrase 2 P00918 CAH2_HUMAN Homo sapiens 2 0.7863
Nitric oxide synthase oxygenase O34453 NOSO_BACSU Bacillus subtilis 4 0.7853
Nitric oxide synthase oxygenase O34453 NOSO_BACSU Bacillus subtilis 4 0.7853
CmeR Q7B8P6 Q7B8P6_CAMJU Campylobacter jejuni 3 0.7847
CmeR Q7B8P6 Q7B8P6_CAMJU Campylobacter jejuni 3 0.7847
Aldo-keto reductase family 1 member D1 P51857 AK1D1_HUMAN Homo sapiens 3 0.7841
Aldo-keto reductase family 1 member D1 P51857 AK1D1_HUMAN Homo sapiens 3 0.7841
Estrogen receptor P03372 ESR1_HUMAN Homo sapiens 3 0.7820
Estrogen receptor P03372 ESR1_HUMAN Homo sapiens 3 0.7820
Adenylate cyclase type 5 P30803 ADCY5_CANLF Canis lupus familiaris 4 0.7787
Adenylate cyclase type 5 P30803 ADCY5_CANLF Canis lupus familiaris 4 0.7787
Aldo-keto reductase family 1 member D1 P51857 AK1D1_HUMAN Homo sapiens 3 0.7753
Aldo-keto reductase family 1 member D1 P51857 AK1D1_HUMAN Homo sapiens 3 0.7753
Cyclin-dependent kinase 2 P24941 CDK2_HUMAN Homo sapiens 3 0.7744
Cyclin-dependent kinase 2 P24941 CDK2_HUMAN Homo sapiens 3 0.7744
Queuine tRNA-ribosyltransferase P28720 TGT_ZYMMO Zymomonas mobilis subsp. mobilis 3 0.7734
Queuine tRNA-ribosyltransferase P28720 TGT_ZYMMO Zymomonas mobilis subsp. mobilis 3 0.7734
HTH-type transcriptional repressor PurR P0ACP7 PURR_ECOLI Escherichia coli 3 0.7713
HTH-type transcriptional repressor PurR P0ACP7 PURR_ECOLI Escherichia coli 3 0.7713
High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A O76083 PDE9A_HUMAN Homo sapiens 3 0.7707
High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A O76083 PDE9A_HUMAN Homo sapiens 3 0.7707
High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A O76083 PDE9A_HUMAN Homo sapiens 3 0.7706
High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A O76083 PDE9A_HUMAN Homo sapiens 3 0.7706
Chitinase Q54276 Q54276_SERMA Serratia marcescens 3 0.7695
Chitinase Q54276 Q54276_SERMA Serratia marcescens 3 0.7695
Steroid Delta-isomerase P00947 SDIS_COMTE Comamonas testosteroni 3 0.7638
Steroid Delta-isomerase P00947 SDIS_COMTE Comamonas testosteroni 3 0.7638
Sex hormone-binding globulin P04278 SHBG_HUMAN Homo sapiens 3 0.7632
Sex hormone-binding globulin P04278 SHBG_HUMAN Homo sapiens 3 0.7632
Pteridine reductase, putative Q581W1 Q581W1_TRYB2 Trypanosoma brucei brucei 3 0.7626
Pteridine reductase, putative Q581W1 Q581W1_TRYB2 Trypanosoma brucei brucei 3 0.7626
Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial Q33862 Q33862_ASCSU Ascaris suum 3 0.7625
Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial Q33862 Q33862_ASCSU Ascaris suum 3 0.7625
cAMP-dependent protein kinase catalytic subunit alpha P17612 KAPCA_HUMAN Homo sapiens 3 0.7624
cAMP-dependent protein kinase catalytic subunit alpha P17612 KAPCA_HUMAN Homo sapiens 3 0.7624
Nuclear receptor subfamily 1 group I member 2 O75469 NR1I2_HUMAN Homo sapiens 3 0.7617
Nuclear receptor subfamily 1 group I member 2 O75469 NR1I2_HUMAN Homo sapiens 3 0.7617
Photosynthetic reaction center cytochrome c subunit P07173 CYCR_BLAVI Blastochloris viridis 3 0.7612
Photosynthetic reaction center cytochrome c subunit P07173 CYCR_BLAVI Blastochloris viridis 3 0.7612
3',5'-cyclic-AMP phosphodiesterase 4D Q08499 PDE4D_HUMAN Homo sapiens 3 0.7592
3',5'-cyclic-AMP phosphodiesterase 4D Q08499 PDE4D_HUMAN Homo sapiens 3 0.7592
17-beta-hydroxysteroid dehydrogenase type 1 P14061 DHB1_HUMAN Homo sapiens 3 0.7583
17-beta-hydroxysteroid dehydrogenase type 1 P14061 DHB1_HUMAN Homo sapiens 3 0.7583
Aldo-keto reductase family 1 member D1 P51857 AK1D1_HUMAN Homo sapiens 3 0.7578
Aldo-keto reductase family 1 member D1 P51857 AK1D1_HUMAN Homo sapiens 3 0.7578
Heat shock protein HSP 90-alpha P07900 HS90A_HUMAN Homo sapiens 3 0.7571
Heat shock protein HSP 90-alpha P07900 HS90A_HUMAN Homo sapiens 3 0.7571
Gastrotropin P51161 FABP6_HUMAN Homo sapiens 3 0.7567
Gastrotropin P51161 FABP6_HUMAN Homo sapiens 3 0.7567
Sulfotransferase 2A1 Q06520 ST2A1_HUMAN Homo sapiens 3 0.7561
Sulfotransferase 2A1 Q06520 ST2A1_HUMAN Homo sapiens 3 0.7561
Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase Q9TQS6 DHDH_MACFA Macaca fascicularis 3 0.7559
Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase Q9TQS6 DHDH_MACFA Macaca fascicularis 3 0.7559
5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase Q81LL4 MTNN_BACAN Bacillus anthracis 3 0.7548
5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase Q81LL4 MTNN_BACAN Bacillus anthracis 3 0.7548
Photosynthetic reaction center cytochrome c subunit P07173 CYCR_BLAVI Blastochloris viridis 3 0.7537
Photosynthetic reaction center cytochrome c subunit P07173 CYCR_BLAVI Blastochloris viridis 3 0.7537
HTH-type transcriptional repressor PurR P0ACP7 PURR_ECOLI Escherichia coli 3 0.7535
HTH-type transcriptional repressor PurR P0ACP7 PURR_ECOLI Escherichia coli 3 0.7535
Ferrochelatase, mitochondrial P22830 HEMH_HUMAN Homo sapiens 3 0.7522
Ferrochelatase, mitochondrial P22830 HEMH_HUMAN Homo sapiens 3 0.7522
Steroid Delta-isomerase P00947 SDIS_COMTE Comamonas testosteroni 3 0.7514
Steroid Delta-isomerase P00947 SDIS_COMTE Comamonas testosteroni 3 0.7514
Dihydropteroate synthase Q81VW8 Q81VW8_BACAN Bacillus anthracis 4 0.7497
Dihydropteroate synthase Q81VW8 Q81VW8_BACAN Bacillus anthracis 4 0.7497
Endoplasmin P41148 ENPL_CANLF Canis lupus familiaris 4 0.7459
Endoplasmin P41148 ENPL_CANLF Canis lupus familiaris 4 0.7459
HTH-type transcriptional repressor PurR P0ACP7 PURR_ECOLI Escherichia coli 3 0.7454
HTH-type transcriptional repressor PurR P0ACP7 PURR_ECOLI Escherichia coli 3 0.7454
APH(2'')-Id O68183 O68183_ENTCA Enterococcus casseliflavus 4 0.7451
APH(2'')-Id O68183 O68183_ENTCA Enterococcus casseliflavus 4 0.7451
Beta-1 adrenergic receptor P07700 ADRB1_MELGA Meleagris gallopavo 3 0.7424
Beta-1 adrenergic receptor P07700 ADRB1_MELGA Meleagris gallopavo 3 0.7424
Serine/threonine-protein kinase Chk1 O14757 CHK1_HUMAN Homo sapiens 3 0.7388
Serine/threonine-protein kinase Chk1 O14757 CHK1_HUMAN Homo sapiens 3 0.7388
TDP-4-oxo-6-deoxy-alpha-D-glucose-3,4-oxoisomerase Q6T1W8 FDTA_ANETH Aneurinibacillus thermoaerophilus 3 0.7387
TDP-4-oxo-6-deoxy-alpha-D-glucose-3,4-oxoisomerase Q6T1W8 FDTA_ANETH Aneurinibacillus thermoaerophilus 3 0.7387
11-beta-hydroxysteroid dehydrogenase 1 P50172 DHI1_MOUSE Mus musculus 3 0.7364
11-beta-hydroxysteroid dehydrogenase 1 P50172 DHI1_MOUSE Mus musculus 3 0.7364
Retinoic acid receptor RXR-alpha P19793 RXRA_HUMAN Homo sapiens 3 0.7353
Retinoic acid receptor RXR-alpha P19793 RXRA_HUMAN Homo sapiens 3 0.7353
Heat shock protein HSP 90-alpha P07900 HS90A_HUMAN Homo sapiens 3 0.7342
Adenylate cyclase type 5 P30803 ADCY5_CANLF Canis lupus familiaris 4 0.7342
Heat shock protein HSP 90-alpha P07900 HS90A_HUMAN Homo sapiens 3 0.7342
Adenylate cyclase type 5 P30803 ADCY5_CANLF Canis lupus familiaris 4 0.7342
Sex hormone-binding globulin P04278 SHBG_HUMAN Homo sapiens 3 0.7326
Sex hormone-binding globulin P04278 SHBG_HUMAN Homo sapiens 3 0.7326
LIM domain kinase 1 P53667 LIMK1_HUMAN Homo sapiens 2 0.7321
LIM domain kinase 1 P53667 LIMK1_HUMAN Homo sapiens 2 0.7321
Bromodomain-containing protein 4 O60885 BRD4_HUMAN Homo sapiens 3 0.7320
Bromodomain-containing protein 4 O60885 BRD4_HUMAN Homo sapiens 3 0.7320
Na(+):neurotransmitter symporter (Snf family) O67854 O67854_AQUAE Aquifex aeolicus 3 0.7295
Na(+):neurotransmitter symporter (Snf family) O67854 O67854_AQUAE Aquifex aeolicus 3 0.7295
Pheromone-binding protein ASP1 Q9U9J6 Q9U9J6_APIME Apis mellifera 2 0.7269
Pheromone-binding protein ASP1 Q9U9J6 Q9U9J6_APIME Apis mellifera 2 0.7269
Steroid Delta-isomerase P07445 SDIS_PSEPU Pseudomonas putida 3 0.7262
Steroid Delta-isomerase P07445 SDIS_PSEPU Pseudomonas putida 3 0.7262
3',5'-cyclic-AMP phosphodiesterase 4D Q08499 PDE4D_HUMAN Homo sapiens 3 0.7257
3',5'-cyclic-AMP phosphodiesterase 4D Q08499 PDE4D_HUMAN Homo sapiens 3 0.7257
11-beta-hydroxysteroid dehydrogenase 1 P28845 DHI1_HUMAN Homo sapiens 3 0.7233
11-beta-hydroxysteroid dehydrogenase 1 P28845 DHI1_HUMAN Homo sapiens 3 0.7233
HTH-type transcriptional repressor PurR P0ACP7 PURR_ECOLI Escherichia coli 4 0.7223
HTH-type transcriptional repressor PurR P0ACP7 PURR_ECOLI Escherichia coli 4 0.7223
Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase Q05603 COBT_SALTY Salmonella typhimurium 3 0.7208
Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase Q05603 COBT_SALTY Salmonella typhimurium 3 0.7208
Prothrombin P00734 THRB_HUMAN Homo sapiens 3 0.7206
Prothrombin P00734 THRB_HUMAN Homo sapiens 3 0.7206
Lethal(3)malignant brain tumor-like protein 1 Q9Y468 LMBL1_HUMAN Homo sapiens 3 0.7197
Lethal(3)malignant brain tumor-like protein 1 Q9Y468 LMBL1_HUMAN Homo sapiens 3 0.7197
Serine/threonine-protein kinase Chk1 O14757 CHK1_HUMAN Homo sapiens 3 0.7191
Serine/threonine-protein kinase Chk1 O14757 CHK1_HUMAN Homo sapiens 3 0.7191
Tryptophan synthase alpha chain P00929 TRPA_SALTY Salmonella typhimurium 4 0.7163
Peptidyl-prolyl cis-trans isomerase FKBP5 Q13451 FKBP5_HUMAN Homo sapiens 3 0.7163
Tryptophan synthase alpha chain P00929 TRPA_SALTY Salmonella typhimurium 4 0.7163
Peptidyl-prolyl cis-trans isomerase FKBP5 Q13451 FKBP5_HUMAN Homo sapiens 3 0.7163
3-alpha-hydroxysteroid dehydrogenase P23457 DIDH_RAT Rattus norvegicus 3 0.7160
3-alpha-hydroxysteroid dehydrogenase P23457 DIDH_RAT Rattus norvegicus 3 0.7160
Gag-Pol polyprotein P04585 POL_HV1H2 Human immunodeficiency virus type 1 group M subtype B 4 0.7132
Gag-Pol polyprotein P04585 POL_HV1H2 Human immunodeficiency virus type 1 group M subtype B 4 0.7132
Lactoylglutathione lyase Q9CPU0 LGUL_MOUSE Mus musculus 2 0.7132
Lactoylglutathione lyase Q9CPU0 LGUL_MOUSE Mus musculus 2 0.7132
Steroid Delta-isomerase P00947 SDIS_COMTE Comamonas testosteroni 3 0.7101
Steroid Delta-isomerase P00947 SDIS_COMTE Comamonas testosteroni 3 0.7101
Retinoic acid receptor RXR-alpha P19793 RXRA_HUMAN Homo sapiens 3 0.7098
Retinoic acid receptor RXR-alpha P19793 RXRA_HUMAN Homo sapiens 3 0.7098
L-lactate dehydrogenase A chain P04642 LDHA_RAT Rattus norvegicus 3 0.7094
L-lactate dehydrogenase A chain P04642 LDHA_RAT Rattus norvegicus 3 0.7094
Beta-1 adrenergic receptor P07700 ADRB1_MELGA Meleagris gallopavo 2 0.7091
Beta-1 adrenergic receptor P07700 ADRB1_MELGA Meleagris gallopavo 2 0.7091
Methionine aminopeptidase 2 P9WK19 MAP12_MYCTU Mycobacterium tuberculosis 3 0.7071
Methionine aminopeptidase 2 P9WK19 MAP12_MYCTU Mycobacterium tuberculosis 3 0.7071
Dihydropteroate synthase Q81VW8 Q81VW8_BACAN Bacillus anthracis 4 0.7064
Dihydropteroate synthase Q81VW8 Q81VW8_BACAN Bacillus anthracis 4 0.7064
Androgen receptor P10275 ANDR_HUMAN Homo sapiens 3 0.7062
Androgen receptor P10275 ANDR_HUMAN Homo sapiens 3 0.7062
3-hydroxyanthranilate 3,4-dioxygenase Q1LCS4 3HAO_CUPMC Cupriavidus metallidurans 2 0.7055
Liver carboxylesterase 1 P23141 EST1_HUMAN Homo sapiens 3 0.7055
Liver carboxylesterase 1 P23141 EST1_HUMAN Homo sapiens 3 0.7055
3-hydroxyanthranilate 3,4-dioxygenase Q1LCS4 3HAO_CUPMC Cupriavidus metallidurans 2 0.7055
UDP-galactopyranose mutase Q48485 GLF1_KLEPN Klebsiella pneumoniae 3 0.7044
UDP-galactopyranose mutase Q48485 GLF1_KLEPN Klebsiella pneumoniae 3 0.7044
Mitochondrial poly(A) polymerase F1NBW0 F1NBW0_CHICK Gallus gallus 2 0.7035
Mitochondrial poly(A) polymerase F1NBW0 F1NBW0_CHICK Gallus gallus 2 0.7035
Retinoic acid receptor RXR-alpha P19793 RXRA_HUMAN Homo sapiens 3 0.7031
Retinoic acid receptor RXR-alpha P19793 RXRA_HUMAN Homo sapiens 3 0.7031
High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A O76083 PDE9A_HUMAN Homo sapiens 3 0.7025
High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A O76083 PDE9A_HUMAN Homo sapiens 3 0.7025
Tryptophan synthase alpha chain P00929 TRPA_SALTY Salmonella typhimurium 4 0.7021
Tryptophan synthase alpha chain P00929 TRPA_SALTY Salmonella typhimurium 4 0.7021
Androgen receptor P10275 ANDR_HUMAN Homo sapiens 3 0.7006
Androgen receptor P10275 ANDR_HUMAN Homo sapiens 3 0.7006

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