Methyl phloroglucinol 2-MeB - Compound Card

Methyl phloroglucinol 2-MeB

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Methyl phloroglucinol 2-MeB

Structure
Zoomed Structure
  • Family: Plantae - Rosaceae
  • Kingdom: Plantae
  • Class: Phenolic
Canonical Smiles CCC(C(=O)c1c(O)cc(c(c1O)C)O)C
InChI InChI=1S/C12H16O4/c1-4-6(2)11(15)10-9(14)5-8(13)7(3)12(10)16/h5-6,13-14,16H,4H2,1-3H3
InChIKey XGJQNJPFHJCFDN-UHFFFAOYSA-N
Formula C12H16O4
HBA 4
HBD 3
MW 224.26
Rotatable Bonds 3
TPSA 77.76
LogP 2.34
Number Rings 1
Number Aromatic Rings 1
Heavy Atom Count 16
Formal Charge 0
Fraction CSP3 0.42
Exact Mass 224.1
Number of Lipinski Rule Violations 0
# Species Family Kingdom NCBI Taxonomy ID
1 Hagenia abyssinica Rosaceae Plantae 57921

Showing of synonyms

  • Gemech M, Dagne E. (2007). Chemical study of anti-termite extract of saw dust of Hagenia abyssinica. M.Sc. Thesis-4, Addis Ababa University, Ethiopia, 2007. [View] [PubMed]
Pubchem: 91825836

No compound-protein relationship available.

Structure

SMILES: c1ccccc1

Level: 0

Mol. Weight: 224.26 g/mol

No bioactivities available.

Absorption

Caco-2 (logPapp)
-4.67
Human Oral Bioavailability 20%
Bioavailable
Human Intestinal Absorption
Absorbed
Madin-Darby Canine Kidney
-4.79
Human Oral Bioavailability 50%
Bioavailable
P-Glycoprotein Inhibitor
Non-Inhibitor
P-Glycoprotein Substrate
Non-Substrate
Skin Permeability
-1.69

Distribution

Blood-Brain Barrier (CNS)
-
Blood-Brain Barrier
Penetrable
Fraction Unbound (Human)
0.54
Plasma Protein Binding
36.27
Steady State Volume of Distribution
-

Metabolism

Breast Cancer Resistance Protein
Non-Inhibitor
CYP 1A2 Inhibitor
Non-Inhibitor
CYP 1A2 Substrate
Substrate
CYP 2C19 Inhibitor
Inhibitor
CYP 2C19 Substrate
Substrate
CYP 2C9 Inhibitor
Inhibitor
CYP 2C9 Substrate
Substrate
CYP 2D6 Inhibitor
Non-Inhibitor
CYP 2D6 Substrate
Non-Substrate
CYP 3A4 Inhibitor
Inhibitor
CYP 3A4 Substrate
Non-Substrate
OATP1B1
Non-Inhibitor
OATP1B3
Non-Inhibitor

Excretion

Clearance
13.11
Organic Cation Transporter 2
Non-Inhibitor
Half-Life of Drug
-

Toxicity

AMES Mutagenesis
Safe
Avian
Safe
Bee
Toxic
Bioconcentration Factor
0.51
Biodegradation
Toxic
Carcinogenesis
Safe
Crustacean
Safe
Liver Injury I (DILI)
Safe
Eye Corrosion
Safe
Eye Irritation
Toxic
Maximum Tolerated Dose
-0.05
Liver Injury II
Safe
hERG Blockers
Safe
Daphnia Maga
4.32
Micronucleos
Toxic
NR-AhR
Toxic
NR-AR
Safe
NR-AR-LBD
Safe
NR-Aromatase
Safe
NR-ER
Safe
NR-ER-LBD
Safe
NR-GR
Safe
NR-PPAR-gamma
Safe
NR-TR
Safe
T. Pyriformis
4.38
Rat (Acute)
2.17
Rat (Chronic Oral)
2.87
Fathead Minnow
3.98
Respiratory Disease
Toxic
Skin Sensitisation
Toxic
SR-ARE
Safe
SR-ATAD5
Safe
SR-HSE
Safe
SR-MMP
Toxic
SR-p53
Safe

General Properties

Boiling Point
334.34
Hydration Free Energy
-11.37
Log(D) at pH=7.4
2.1
Log(P)
3.67
Log S
-3.32
Log(Vapor Pressure)
-4.64
Melting Point
113.54
pKa Acid
6.0
pKa Basic
8.6
Protein Name UniProt ID Entry Name Species #Pharmacophore Points Probability (0.7 ≤ Tversky Score ≤ 1.0)
3',5'-cyclic-AMP phosphodiesterase 4D Q08499 PDE4D_HUMAN Homo sapiens 3 0.9133
3',5'-cyclic-AMP phosphodiesterase 4D Q08499 PDE4D_HUMAN Homo sapiens 3 0.9133
HTH-type transcriptional repressor PurR P0ACP7 PURR_ECOLI Escherichia coli 3 0.9007
HTH-type transcriptional repressor PurR P0ACP7 PURR_ECOLI Escherichia coli 3 0.9007
Sex hormone-binding globulin P04278 SHBG_HUMAN Homo sapiens 3 0.8828
Sex hormone-binding globulin P04278 SHBG_HUMAN Homo sapiens 3 0.8828
Heat shock protein HSP 90-alpha P07900 HS90A_HUMAN Homo sapiens 3 0.8825
Heat shock protein HSP 90-alpha P07900 HS90A_HUMAN Homo sapiens 3 0.8825
Steroid Delta-isomerase P07445 SDIS_PSEPU Pseudomonas putida 3 0.8744
Steroid Delta-isomerase P07445 SDIS_PSEPU Pseudomonas putida 3 0.8744
Toxoflavin degrading enzyme E3SET7 E3SET7_PAEPO Paenibacillus polymyxa 3 0.8709
Toxoflavin degrading enzyme E3SET7 E3SET7_PAEPO Paenibacillus polymyxa 3 0.8709
Sex hormone-binding globulin P04278 SHBG_HUMAN Homo sapiens 3 0.8622
Sex hormone-binding globulin P04278 SHBG_HUMAN Homo sapiens 3 0.8622
cAMP-dependent protein kinase catalytic subunit alpha P17612 KAPCA_HUMAN Homo sapiens 3 0.8619
cAMP-dependent protein kinase catalytic subunit alpha P17612 KAPCA_HUMAN Homo sapiens 3 0.8619
Soluble acetylcholine receptor Q8WSF8 Q8WSF8_APLCA Aplysia californica 3 0.8579
Soluble acetylcholine receptor Q8WSF8 Q8WSF8_APLCA Aplysia californica 3 0.8579
ATP-dependent molecular chaperone HSP82 P02829 HSP82_YEAST Saccharomyces cerevisiae 3 0.8555
ATP-dependent molecular chaperone HSP82 P02829 HSP82_YEAST Saccharomyces cerevisiae 3 0.8555
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 P04191 AT2A1_RABIT Oryctolagus cuniculus 3 0.8554
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 P04191 AT2A1_RABIT Oryctolagus cuniculus 3 0.8554
Endoplasmin P41148 ENPL_CANLF Canis lupus familiaris 3 0.8549
Endoplasmin P41148 ENPL_CANLF Canis lupus familiaris 3 0.8549
Chitinase Q54276 Q54276_SERMA Serratia marcescens 3 0.8544
Chitinase Q54276 Q54276_SERMA Serratia marcescens 3 0.8544
Aldo-keto reductase family 1 member D1 P51857 AK1D1_HUMAN Homo sapiens 3 0.8537
Aldo-keto reductase family 1 member D1 P51857 AK1D1_HUMAN Homo sapiens 3 0.8537
Cyclin-dependent kinase 2 P24941 CDK2_HUMAN Homo sapiens 3 0.8500
Cyclin-dependent kinase 2 P24941 CDK2_HUMAN Homo sapiens 3 0.8500
Gastrotropin P51161 FABP6_HUMAN Homo sapiens 3 0.8434
Gastrotropin P51161 FABP6_HUMAN Homo sapiens 3 0.8434
Sulfide-quinone reductase B7JBP8 SQRD_ACIF2 Acidithiobacillus ferrooxidans) 3 0.8424
Sulfide-quinone reductase B7JBP8 SQRD_ACIF2 Acidithiobacillus ferrooxidans) 3 0.8424
3',5'-cyclic-AMP phosphodiesterase 4D Q08499 PDE4D_HUMAN Homo sapiens 3 0.8346
3',5'-cyclic-AMP phosphodiesterase 4D Q08499 PDE4D_HUMAN Homo sapiens 3 0.8346
ATP-dependent molecular chaperone HSP82 P02829 HSP82_YEAST Saccharomyces cerevisiae 3 0.8318
ATP-dependent molecular chaperone HSP82 P02829 HSP82_YEAST Saccharomyces cerevisiae 3 0.8318
Flavoredoxin Q72HI0 Q72HI0_THET2 Thermus thermophilus 3 0.8297
Flavoredoxin Q72HI0 Q72HI0_THET2 Thermus thermophilus 3 0.8297
Mycinamicin III 3''-O-methyltransferase Q49492 MYCF_MICGR Micromonospora griseorubida 2 0.8233
Mycinamicin III 3''-O-methyltransferase Q49492 MYCF_MICGR Micromonospora griseorubida 2 0.8233
HTH-type transcriptional repressor PurR P0ACP7 PURR_ECOLI Escherichia coli 3 0.8219
HTH-type transcriptional repressor PurR P0ACP7 PURR_ECOLI Escherichia coli 3 0.8219
Photosynthetic reaction center cytochrome c subunit P07173 CYCR_BLAVI Blastochloris viridis 3 0.8200
Photosynthetic reaction center cytochrome c subunit P07173 CYCR_BLAVI Blastochloris viridis 3 0.8200
Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial Q0QF01 SDHA_PIG Sus scrofa 3 0.8193
Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial Q0QF01 SDHA_PIG Sus scrofa 3 0.8193
HTH-type transcriptional repressor PurR P0ACP7 PURR_ECOLI Escherichia coli 3 0.8172
HTH-type transcriptional repressor PurR P0ACP7 PURR_ECOLI Escherichia coli 3 0.8172
HTH-type transcriptional repressor PurR P0ACP7 PURR_ECOLI Escherichia coli 3 0.8145
HTH-type transcriptional repressor PurR P0ACP7 PURR_ECOLI Escherichia coli 3 0.8145
Achbp I6L8L2 I6L8L2_CAPTE Capitella teleta 3 0.8133
Achbp I6L8L2 I6L8L2_CAPTE Capitella teleta 3 0.8133
ATP-dependent molecular chaperone HSP82 P02829 HSP82_YEAST Saccharomyces cerevisiae 3 0.8101
ATP-dependent molecular chaperone HSP82 P02829 HSP82_YEAST Saccharomyces cerevisiae 3 0.8101
Serine/threonine-protein kinase Chk1 O14757 CHK1_HUMAN Homo sapiens 3 0.8099
Serine/threonine-protein kinase Chk1 O14757 CHK1_HUMAN Homo sapiens 3 0.8099
Purine nucleoside phosphorylase DeoD-type P0ABP8 DEOD_ECOLI Escherichia coli 3 0.8052
Purine nucleoside phosphorylase DeoD-type P0ABP8 DEOD_ECOLI Escherichia coli 3 0.8052
Tryptophan synthase alpha chain P00929 TRPA_SALTY Salmonella typhimurium 4 0.8044
Tryptophan synthase alpha chain P00929 TRPA_SALTY Salmonella typhimurium 4 0.8044
Serine/threonine-protein kinase Chk2 O96017 CHK2_HUMAN Homo sapiens 3 0.8033
Serine/threonine-protein kinase Chk2 O96017 CHK2_HUMAN Homo sapiens 3 0.8033
Succinate dehydrogenase flavoprotein subunit P0AC41 SDHA_ECOLI Escherichia coli 3 0.8027
Succinate dehydrogenase flavoprotein subunit P0AC41 SDHA_ECOLI Escherichia coli 3 0.8027
Soluble cytochrome b562 P0ABE7 C562_ECOLX Escherichia coli 3 0.8007
Soluble cytochrome b562 P0ABE7 C562_ECOLX Escherichia coli 3 0.8007
Mycinamicin III 3''-O-methyltransferase Q49492 MYCF_MICGR Micromonospora griseorubida 2 0.7989
Mycinamicin III 3''-O-methyltransferase Q49492 MYCF_MICGR Micromonospora griseorubida 2 0.7989
3',5'-cyclic-AMP phosphodiesterase 4D Q08499 PDE4D_HUMAN Homo sapiens 3 0.7969
3',5'-cyclic-AMP phosphodiesterase 4D Q08499 PDE4D_HUMAN Homo sapiens 3 0.7969
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 P04191 AT2A1_RABIT Oryctolagus cuniculus 3 0.7961
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 P04191 AT2A1_RABIT Oryctolagus cuniculus 3 0.7961
Lethal(3)malignant brain tumor-like protein 1 Q9Y468 LMBL1_HUMAN Homo sapiens 3 0.7948
Lethal(3)malignant brain tumor-like protein 1 Q9Y468 LMBL1_HUMAN Homo sapiens 3 0.7948
ATP-dependent molecular chaperone HSP82 P02829 HSP82_YEAST Saccharomyces cerevisiae 3 0.7946
ATP-dependent molecular chaperone HSP82 P02829 HSP82_YEAST Saccharomyces cerevisiae 3 0.7946
Carbonic anhydrase 2 P00918 CAH2_HUMAN Homo sapiens 3 0.7941
Carbonic anhydrase 2 P00918 CAH2_HUMAN Homo sapiens 3 0.7941
Tryptophan synthase alpha chain P00929 TRPA_SALTY Salmonella typhimurium 4 0.7924
Pteridine reductase, putative Q581W1 Q581W1_TRYB2 Trypanosoma brucei brucei 3 0.7924
Pteridine reductase, putative Q581W1 Q581W1_TRYB2 Trypanosoma brucei brucei 3 0.7924
Tryptophan synthase alpha chain P00929 TRPA_SALTY Salmonella typhimurium 4 0.7924
Steroid Delta-isomerase P07445 SDIS_PSEPU Pseudomonas putida 2 0.7914
Steroid Delta-isomerase P07445 SDIS_PSEPU Pseudomonas putida 2 0.7914
Nitric oxide synthase oxygenase O34453 NOSO_BACSU Bacillus subtilis 4 0.7894
Nitric oxide synthase oxygenase O34453 NOSO_BACSU Bacillus subtilis 4 0.7894
AGAP003309-PA A0A1U7F4W2 A0A1U7F4W2_ANOGA Anopheles gambiae 3 0.7872
AGAP003309-PA A0A1U7F4W2 A0A1U7F4W2_ANOGA Anopheles gambiae 3 0.7872
Trichothecene 15-O-acetyltransferase TRI3 Q9C1B7 TRI3_FUSSP Fusarium sporotrichioides 3 0.7865
Trichothecene 15-O-acetyltransferase TRI3 Q9C1B7 TRI3_FUSSP Fusarium sporotrichioides 3 0.7865
11-beta-hydroxysteroid dehydrogenase 1 P50172 DHI1_MOUSE Mus musculus 3 0.7804
11-beta-hydroxysteroid dehydrogenase 1 P50172 DHI1_MOUSE Mus musculus 3 0.7804
Ribosomal small subunit pseudouridine synthase A P0AA43 RSUA_ECOLI Escherichia coli 3 0.7796
Ribosomal small subunit pseudouridine synthase A P0AA43 RSUA_ECOLI Escherichia coli 3 0.7796
Photosynthetic reaction center cytochrome c subunit P07173 CYCR_BLAVI Blastochloris viridis 3 0.7795
Photosynthetic reaction center cytochrome c subunit P07173 CYCR_BLAVI Blastochloris viridis 3 0.7795
Carbonic anhydrase 2 P00918 CAH2_HUMAN Homo sapiens 2 0.7773
Carbonic anhydrase 2 P00918 CAH2_HUMAN Homo sapiens 2 0.7773
5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase Q81LL4 MTNN_BACAN Bacillus anthracis 3 0.7761
5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase Q81LL4 MTNN_BACAN Bacillus anthracis 3 0.7761
Adenylate cyclase type 5 P30803 ADCY5_CANLF Canis lupus familiaris 4 0.7759
Adenylate cyclase type 5 P30803 ADCY5_CANLF Canis lupus familiaris 4 0.7759
Queuine tRNA-ribosyltransferase P28720 TGT_ZYMMO Zymomonas mobilis subsp. mobilis 3 0.7743
Queuine tRNA-ribosyltransferase P28720 TGT_ZYMMO Zymomonas mobilis subsp. mobilis 3 0.7743
Aldo-keto reductase family 1 member B1 P15121 ALDR_HUMAN Homo sapiens 3 0.7712
Aldo-keto reductase family 1 member B1 P15121 ALDR_HUMAN Homo sapiens 3 0.7712
Phenylalanine-4-hydroxylase P00439 PH4H_HUMAN Homo sapiens 3 0.7644
Phenylalanine-4-hydroxylase P00439 PH4H_HUMAN Homo sapiens 3 0.7644
Nitric oxide synthase, inducible P29477 NOS2_MOUSE Mus musculus 4 0.7633
Nitric oxide synthase, inducible P29477 NOS2_MOUSE Mus musculus 4 0.7633
Tetracycline repressor protein class H P51561 TETR8_PASMD Pasteurella multocida 2 0.7627
Tetracycline repressor protein class H P51561 TETR8_PASMD Pasteurella multocida 2 0.7627
Nuclear receptor subfamily 1 group I member 2 O75469 NR1I2_HUMAN Homo sapiens 3 0.7614
Nuclear receptor subfamily 1 group I member 2 O75469 NR1I2_HUMAN Homo sapiens 3 0.7614
HTH-type transcriptional repressor PurR P0ACP7 PURR_ECOLI Escherichia coli 3 0.7597
HTH-type transcriptional repressor PurR P0ACP7 PURR_ECOLI Escherichia coli 3 0.7597
Proton-gated ion channel Q7NDN8 GLIC_GLOVI Gloeobacter violaceus 3 0.7592
Proton-gated ion channel Q7NDN8 GLIC_GLOVI Gloeobacter violaceus 3 0.7592
Abscisic acid receptor PYR1 O49686 PYR1_ARATH Arabidopsis thaliana 3 0.7568
Abscisic acid receptor PYR1 O49686 PYR1_ARATH Arabidopsis thaliana 3 0.7568
TDP-4-oxo-6-deoxy-alpha-D-glucose-3,4-oxoisomerase Q6T1W8 FDTA_ANETH Aneurinibacillus thermoaerophilus 3 0.7560
TDP-4-oxo-6-deoxy-alpha-D-glucose-3,4-oxoisomerase Q6T1W8 FDTA_ANETH Aneurinibacillus thermoaerophilus 3 0.7560
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 P04191 AT2A1_RABIT Oryctolagus cuniculus 4 0.7557
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 P04191 AT2A1_RABIT Oryctolagus cuniculus 4 0.7557
HTH-type transcriptional repressor PurR P0ACP7 PURR_ECOLI Escherichia coli 4 0.7546
HTH-type transcriptional repressor PurR P0ACP7 PURR_ECOLI Escherichia coli 4 0.7546
Gag-Pol polyprotein P04585 POL_HV1H2 Human immunodeficiency virus type 1 group M subtype B 3 0.7539
Gag-Pol polyprotein P04585 POL_HV1H2 Human immunodeficiency virus type 1 group M subtype B 3 0.7539
Heat shock protein HSP 90-alpha P07900 HS90A_HUMAN Homo sapiens 3 0.7494
Heat shock protein HSP 90-alpha P07900 HS90A_HUMAN Homo sapiens 3 0.7494
Na(+):neurotransmitter symporter (Snf family) O67854 O67854_AQUAE Aquifex aeolicus 3 0.7491
Na(+):neurotransmitter symporter (Snf family) O67854 O67854_AQUAE Aquifex aeolicus 3 0.7491
Abscisic acid receptor PYL3 Q9SSM7 PYL3_ARATH Arabidopsis thaliana 3 0.7479
Abscisic acid receptor PYL3 Q9SSM7 PYL3_ARATH Arabidopsis thaliana 3 0.7479
Polyprotein Q80J95 Q80J95_9CALI Murine norovirus 1 3 0.7431
Polyprotein Q80J95 Q80J95_9CALI Murine norovirus 1 3 0.7431
rRNA N-glycosylase D9J2T9 D9J2T9_MOMBA Momordica balsamina 3 0.7413
rRNA N-glycosylase D9J2T9 D9J2T9_MOMBA Momordica balsamina 3 0.7413
Adenylate cyclase type 5 P30803 ADCY5_CANLF Canis lupus familiaris 3 0.7400
Adenylate cyclase type 5 P30803 ADCY5_CANLF Canis lupus familiaris 3 0.7400
Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase Q9TQS6 DHDH_MACFA Macaca fascicularis 3 0.7395
Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase Q9TQS6 DHDH_MACFA Macaca fascicularis 3 0.7395
Retinoic acid receptor RXR-alpha P19793 RXRA_HUMAN Homo sapiens 3 0.7374
Retinoic acid receptor RXR-alpha P19793 RXRA_HUMAN Homo sapiens 3 0.7374
Prothrombin P00734 THRB_HUMAN Homo sapiens 3 0.7352
Prothrombin P00734 THRB_HUMAN Homo sapiens 3 0.7352
Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase F6MZ55 F6MZ55_9FIRM Sporomusa ovata 3 0.7338
Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase F6MZ55 F6MZ55_9FIRM Sporomusa ovata 3 0.7338
Chloramphenicol acetyltransferase P62577 CAT_ECOLX Escherichia coli 2 0.7319
Chloramphenicol acetyltransferase P62577 CAT_ECOLX Escherichia coli 2 0.7319
Bacteriorhodopsin P02945 BACR_HALSA Halobacterium salinarum 3 0.7315
Bacteriorhodopsin P02945 BACR_HALSA Halobacterium salinarum 3 0.7315
Peptidyl-prolyl cis-trans isomerase FKBP5 Q13451 FKBP5_HUMAN Homo sapiens 3 0.7313
Peptidyl-prolyl cis-trans isomerase FKBP5 Q13451 FKBP5_HUMAN Homo sapiens 3 0.7313
Gag-Pol polyprotein P03366 POL_HV1B1 Human immunodeficiency virus type 1 group M subtype B 3 0.7310
Gag-Pol polyprotein P03366 POL_HV1B1 Human immunodeficiency virus type 1 group M subtype B 3 0.7310
Pteridine reductase, putative Q581W1 Q581W1_TRYB2 Trypanosoma brucei brucei 4 0.7309
Pteridine reductase, putative Q581W1 Q581W1_TRYB2 Trypanosoma brucei brucei 4 0.7309
3',5'-cyclic-AMP phosphodiesterase 4D Q08499 PDE4D_HUMAN Homo sapiens 3 0.7279
3',5'-cyclic-AMP phosphodiesterase 4D Q08499 PDE4D_HUMAN Homo sapiens 3 0.7279
Adenylate cyclase type 5 P30803 ADCY5_CANLF Canis lupus familiaris 4 0.7274
Adenylate cyclase type 5 P30803 ADCY5_CANLF Canis lupus familiaris 4 0.7274
Serine/threonine-protein kinase Chk1 O14757 CHK1_HUMAN Homo sapiens 3 0.7272
Serine/threonine-protein kinase Chk1 O14757 CHK1_HUMAN Homo sapiens 3 0.7272
Peptidyl-prolyl cis-trans isomerase FKBP1A P62942 FKB1A_HUMAN Homo sapiens 3 0.7269
Peptidyl-prolyl cis-trans isomerase FKBP1A P62942 FKB1A_HUMAN Homo sapiens 3 0.7269
Beta-1 adrenergic receptor P07700 ADRB1_MELGA Meleagris gallopavo 3 0.7267
Beta-1 adrenergic receptor P07700 ADRB1_MELGA Meleagris gallopavo 3 0.7267
Cellular retinol-binding protein type II Q8UVG6 Q8UVG6_DANRE Danio rerio 3 0.7250
Cellular retinol-binding protein type II Q8UVG6 Q8UVG6_DANRE Danio rerio 3 0.7250
Bifunctional dihydrofolate reductase-thymidylate synthase P13922 DRTS_PLAFK Plasmodium falciparum 2 0.7249
Bifunctional dihydrofolate reductase-thymidylate synthase P13922 DRTS_PLAFK Plasmodium falciparum 2 0.7249
ActVA 6 protein Q53908 Q53908_STRCH Streptomyces coelicolor 3 0.7244
ActVA 6 protein Q53908 Q53908_STRCH Streptomyces coelicolor 3 0.7244
Retinoic acid receptor RXR-alpha P19793 RXRA_HUMAN Homo sapiens 3 0.7243
Retinoic acid receptor RXR-alpha P19793 RXRA_HUMAN Homo sapiens 3 0.7243
Gag-Pol polyprotein P03366 POL_HV1B1 Human immunodeficiency virus type 1 group M subtype B 3 0.7237
Gag-Pol polyprotein P03366 POL_HV1B1 Human immunodeficiency virus type 1 group M subtype B 3 0.7237
Steroid Delta-isomerase P00947 SDIS_COMTE Comamonas testosteroni 3 0.7233
Steroid Delta-isomerase P00947 SDIS_COMTE Comamonas testosteroni 3 0.7233
Tryptophan synthase alpha chain P00929 TRPA_SALTY Salmonella typhimurium 3 0.7232
Tryptophan synthase alpha chain P00929 TRPA_SALTY Salmonella typhimurium 3 0.7232
Steroid Delta-isomerase P00947 SDIS_COMTE Comamonas testosteroni 2 0.7230
Steroid Delta-isomerase P00947 SDIS_COMTE Comamonas testosteroni 2 0.7230
Steroid Delta-isomerase P00947 SDIS_COMTE Comamonas testosteroni 3 0.7230
Steroid Delta-isomerase P00947 SDIS_COMTE Comamonas testosteroni 3 0.7230
Androgen receptor P10275 ANDR_HUMAN Homo sapiens 2 0.7207
Androgen receptor P10275 ANDR_HUMAN Homo sapiens 2 0.7207
Casein kinase II subunit alpha' P19784 CSK22_HUMAN Homo sapiens 2 0.7201
Casein kinase II subunit alpha' P19784 CSK22_HUMAN Homo sapiens 2 0.7201
Sex hormone-binding globulin P04278 SHBG_HUMAN Homo sapiens 3 0.7189
Sex hormone-binding globulin P04278 SHBG_HUMAN Homo sapiens 3 0.7189
High affinity 3',5'-cyclic-AMP phosphodiesterase 7A Q13946 PDE7A_HUMAN Homo sapiens 3 0.7188
High affinity 3',5'-cyclic-AMP phosphodiesterase 7A Q13946 PDE7A_HUMAN Homo sapiens 3 0.7188
Bromodomain-containing protein 4 O60885 BRD4_HUMAN Homo sapiens 3 0.7187
Bromodomain-containing protein 4 O60885 BRD4_HUMAN Homo sapiens 3 0.7187
Delta-type opioid receptor P41143 OPRD_HUMAN Homo sapiens 4 0.7163
Delta-type opioid receptor P41143 OPRD_HUMAN Homo sapiens 4 0.7163
Cyclic nucleotide-binding protein B8FW11 B8FW11_DESHD Desulfitobacterium hafniense 3 0.7162
Cyclic nucleotide-binding protein B8FW11 B8FW11_DESHD Desulfitobacterium hafniense 3 0.7162
Adenylate cyclase type 5 P30803 ADCY5_CANLF Canis lupus familiaris 3 0.7160
Adenylate cyclase type 5 P30803 ADCY5_CANLF Canis lupus familiaris 3 0.7160
Vitamin D3 dihydroxylase P18326 CPXE_STRGO Streptomyces griseolus 3 0.7155
Vitamin D3 dihydroxylase P18326 CPXE_STRGO Streptomyces griseolus 3 0.7155
17-beta-hydroxysteroid dehydrogenase type 1 P14061 DHB1_HUMAN Homo sapiens 3 0.7145
17-beta-hydroxysteroid dehydrogenase type 1 P14061 DHB1_HUMAN Homo sapiens 3 0.7145
Androgen receptor P10275 ANDR_HUMAN Homo sapiens 2 0.7141
Androgen receptor P10275 ANDR_HUMAN Homo sapiens 2 0.7141
Adenylate cyclase type 5 P30803 ADCY5_CANLF Canis lupus familiaris 4 0.7140
Adenylate cyclase type 5 P30803 ADCY5_CANLF Canis lupus familiaris 4 0.7140
Endoplasmin P41148 ENPL_CANLF Canis lupus familiaris 4 0.7138
Endoplasmin P41148 ENPL_CANLF Canis lupus familiaris 4 0.7138
Retinoic acid receptor RXR-alpha P19793 RXRA_HUMAN Homo sapiens 3 0.7136
Retinoic acid receptor RXR-alpha P19793 RXRA_HUMAN Homo sapiens 3 0.7136
Bromodomain-containing protein 2 P25440 BRD2_HUMAN Homo sapiens 2 0.7129
Bromodomain-containing protein 2 P25440 BRD2_HUMAN Homo sapiens 2 0.7129
cGMP-specific 3',5'-cyclic phosphodiesterase O76074 PDE5A_HUMAN Homo sapiens 3 0.7117
cGMP-specific 3',5'-cyclic phosphodiesterase O76074 PDE5A_HUMAN Homo sapiens 3 0.7117
Dihydropteroate synthase Q81VW8 Q81VW8_BACAN Bacillus anthracis 4 0.7110
Dihydropteroate synthase Q81VW8 Q81VW8_BACAN Bacillus anthracis 4 0.7110
Adenylate cyclase type 5 P30803 ADCY5_CANLF Canis lupus familiaris 4 0.7099
Adenylate cyclase type 5 P30803 ADCY5_CANLF Canis lupus familiaris 4 0.7099
p-hydroxyphenylacetate 3-hydroxylase, oxygenase component Q6Q272 HPAH_ACIBA Acinetobacter baumannii 4 0.7099
p-hydroxyphenylacetate 3-hydroxylase, oxygenase component Q6Q272 HPAH_ACIBA Acinetobacter baumannii 4 0.7099
histone deacetylase A5H660 A5H660_SCHMA Schistosoma mansoni 3 0.7073
histone deacetylase A5H660 A5H660_SCHMA Schistosoma mansoni 3 0.7073
Endothiapepsin P11838 CARP_CRYPA Cryphonectria parasitica 3 0.7057
Endothiapepsin P11838 CARP_CRYPA Cryphonectria parasitica 3 0.7057
Beta-1 adrenergic receptor P07700 ADRB1_MELGA Meleagris gallopavo 2 0.7056
Beta-1 adrenergic receptor P07700 ADRB1_MELGA Meleagris gallopavo 2 0.7056
Queuine tRNA-ribosyltransferase P28720 TGT_ZYMMO Zymomonas mobilis subsp. mobilis 3 0.7052
Queuine tRNA-ribosyltransferase P28720 TGT_ZYMMO Zymomonas mobilis subsp. mobilis 3 0.7052
Mitochondrial poly(A) polymerase F1NBW0 F1NBW0_CHICK Gallus gallus 2 0.7047
Mitochondrial poly(A) polymerase F1NBW0 F1NBW0_CHICK Gallus gallus 2 0.7047
Ribonuclease J H9CZL7 H9CZL7_DEIRD Deinococcus radiodurans 3 0.7046
Ribonuclease J H9CZL7 H9CZL7_DEIRD Deinococcus radiodurans 3 0.7046
Albumin P02768 ALBU_HUMAN Homo sapiens 3 0.7032
Albumin P02768 ALBU_HUMAN Homo sapiens 3 0.7032

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