2',4'-dihydroxy-6'-methoxydihydrochalcone - Compound Card

2',4'-dihydroxy-6'-methoxydihydrochalcone

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2',4'-dihydroxy-6'-methoxydihydrochalcone

Structure
Zoomed Structure
  • Family: Plantae - Ptaeroxylaceae
  • Kingdom: Plantae
  • Class: Flavonoid
    • Subclass: Chalcone
Canonical Smiles COc1cc(O)cc(c1C(=O)CCc1ccccc1)O
InChI InChI=1S/C16H16O4/c1-20-15-10-12(17)9-14(19)16(15)13(18)8-7-11-5-3-2-4-6-11/h2-6,9-10,17,19H,7-8H2,1H3
InChIKey FYPYWIYWMVCNCS-UHFFFAOYSA-N
Formula C16H16O4
HBA 4
HBD 2
MW 272.3
Rotatable Bonds 5
TPSA 66.76
LogP 2.92
Number Rings 2
Number Aromatic Rings 2
Heavy Atom Count 20
Formal Charge 0
Fraction CSP3 0.19
Exact Mass 272.1
Number of Lipinski Rule Violations 0
# Species Family Kingdom NCBI Taxonomy ID
1 Polygonum senegalense Polygonaceae Plantae 471708
2 Monanthotaxis trichocarpa Annonaceae Plantae 1202425
3 Cedrelopsis grevei Ptaeroxylaceae Plantae 864332

Showing of synonyms

  • Koorbanally NA, Randrianarivelojosia M, et al. (2003). Chalcones from the seed of Cedrelopsis grevei (Ptaeroxylaceae). Phytochemistry, 2003, 62(8), 1225–1229. [View]
  • Midiwo JO, Gikonyo NK, et al. (1992). Flavonoids of Polygonum senegalense (Meisn) Part II: More surface and internal tissue flavonoid aglycones.. Bulletin of the Chemical Society of Ethiopia,1992,6(2),119-122. [View] [PubMed]
  • Maeda G, van der Wal J, et al. (2020). Oxygenated Cyclohexene Derivatives and Other Constituents from the Roots of Monanthotaxis trichocarpa. Journal of natural products,2020, 83(2), 210-215. [View] [PubMed]
Pubchem: 6483649
Chebi: 180160
Nmrshiftdb2: 60030587

No compound-protein relationship available.

Structure

SMILES: c1ccccc1C(=O)CCc2ccccc2

Level: 1

Mol. Weight: 272.3 g/mol

Structure

SMILES: c1ccccc1

Level: 0

Mol. Weight: 272.3 g/mol

No bioactivities available.

Absorption

Caco-2 (logPapp)
-4.51
Human Oral Bioavailability 20%
Bioavailable
Human Intestinal Absorption
Absorbed
Madin-Darby Canine Kidney
-4.560
Human Oral Bioavailability 50%
Bioavailable
P-Glycoprotein Inhibitor
Non-Inhibitor
P-Glycoprotein Substrate
Non-Substrate
Skin Permeability
-2.11

Distribution

Blood-Brain Barrier (CNS)
-
Blood-Brain Barrier
Penetrable
Fraction Unbound (Human)
1.150
Plasma Protein Binding
62.66
Steady State Volume of Distribution
-

Metabolism

Breast Cancer Resistance Protein
Non-Inhibitor
CYP 1A2 Inhibitor
Inhibitor
CYP 1A2 Substrate
Substrate
CYP 2C19 Inhibitor
Inhibitor
CYP 2C19 Substrate
Non-Substrate
CYP 2C9 Inhibitor
Inhibitor
CYP 2C9 Substrate
Substrate
CYP 2D6 Inhibitor
Non-Inhibitor
CYP 2D6 Substrate
Non-Substrate
CYP 3A4 Inhibitor
Inhibitor
CYP 3A4 Substrate
Non-Substrate
OATP1B1
Non-Inhibitor
OATP1B3
Non-Inhibitor

Excretion

Clearance
7.090
Organic Cation Transporter 2
Non-Inhibitor
Half-Life of Drug
-

Toxicity

AMES Mutagenesis
Safe
Avian
Safe
Bee
Toxic
Bioconcentration Factor
1.160
Biodegradation
Safe
Carcinogenesis
Safe
Crustacean
Safe
Liver Injury I (DILI)
Toxic
Eye Corrosion
Safe
Eye Irritation
Safe
Maximum Tolerated Dose
0.870
Liver Injury II
Toxic
hERG Blockers
Safe
Daphnia Maga
5.840
Micronucleos
Toxic
NR-AhR
Toxic
NR-AR
Safe
NR-AR-LBD
Safe
NR-Aromatase
Safe
NR-ER
Safe
NR-ER-LBD
Safe
NR-GR
Safe
NR-PPAR-gamma
Safe
NR-TR
Safe
T. Pyriformis
3.840
Rat (Acute)
2.080
Rat (Chronic Oral)
2.810
Fathead Minnow
4.380
Respiratory Disease
Safe
Skin Sensitisation
Safe
SR-ARE
Safe
SR-ATAD5
Safe
SR-HSE
Safe
SR-MMP
Toxic
SR-p53
Safe

General Properties

Boiling Point
366.520
Hydration Free Energy
-9.240
Log(D) at pH=7.4
2.810
Log(P)
3.07
Log S
-4.75
Log(Vapor Pressure)
-6.64
Melting Point
108.43
pKa Acid
7.95
pKa Basic
6.69
Protein Name UniProt ID Entry Name Species #Pharmacophore Points Probability (0.7 ≤ Tversky Score ≤ 1.0)
Chitinase A Q9AMP1 Q9AMP1_VIBHA Vibrio harveyi 3 0.9656
Chitinase A Q9AMP1 Q9AMP1_VIBHA Vibrio harveyi 3 0.9656
Serine/threonine-protein kinase 10 O94804 STK10_HUMAN Homo sapiens 3 0.9528
Serine/threonine-protein kinase 10 O94804 STK10_HUMAN Homo sapiens 3 0.9528
Cytohesin-2 Q99418 CYH2_HUMAN Homo sapiens 3 0.9527
Cytohesin-2 Q99418 CYH2_HUMAN Homo sapiens 3 0.9527
Carbonic anhydrase 2 P00918 CAH2_HUMAN Homo sapiens 3 0.9469
Carbonic anhydrase 2 P00918 CAH2_HUMAN Homo sapiens 3 0.9469
Glycogen synthase kinase-3 beta P49841 GSK3B_HUMAN Homo sapiens 3 0.9467
Glycogen synthase kinase-3 beta P49841 GSK3B_HUMAN Homo sapiens 3 0.9467
Thymidylate synthase P00469 TYSY_LACCA Lacticaseibacillus casei 3 0.9457
Thymidylate synthase P00469 TYSY_LACCA Lacticaseibacillus casei 3 0.9457
Heat shock protein HSP 90-alpha P07900 HS90A_HUMAN Homo sapiens 3 0.9445
Heat shock protein HSP 90-alpha P07900 HS90A_HUMAN Homo sapiens 3 0.9445
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A Q9Y233 PDE10_HUMAN Homo sapiens 3 0.9411
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A Q9Y233 PDE10_HUMAN Homo sapiens 3 0.9411
Flavoredoxin Q72HI0 Q72HI0_THET2 Thermus thermophilus 3 0.9408
Flavoredoxin Q72HI0 Q72HI0_THET2 Thermus thermophilus 3 0.9408
Rhodopsin kinase GRK1 P28327 GRK1_BOVIN Bos taurus 3 0.9383
Rhodopsin kinase GRK1 P28327 GRK1_BOVIN Bos taurus 3 0.9383
Carbonic anhydrase 2 P00918 CAH2_HUMAN Homo sapiens 3 0.9372
Carbonic anhydrase 2 P00918 CAH2_HUMAN Homo sapiens 3 0.9372
HTH-type transcriptional repressor PurR P0ACP7 PURR_ECOLI Escherichia coli 3 0.9349
HTH-type transcriptional repressor PurR P0ACP7 PURR_ECOLI Escherichia coli 3 0.9349
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase Q8DNV6 Q8DNV6_STRR6 Streptococcus pneumoniae 3 0.9331
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase Q8DNV6 Q8DNV6_STRR6 Streptococcus pneumoniae 3 0.9331
3',5'-cyclic-AMP phosphodiesterase 4D Q08499 PDE4D_HUMAN Homo sapiens 3 0.9324
3',5'-cyclic-AMP phosphodiesterase 4D Q08499 PDE4D_HUMAN Homo sapiens 3 0.9324
Mycocyclosin synthase P9WPP7 CP121_MYCTU Mycobacterium tuberculosis 3 0.9314
Mycocyclosin synthase P9WPP7 CP121_MYCTU Mycobacterium tuberculosis 3 0.9314
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A Q9QYJ6 PDE10_RAT Rattus norvegicus 3 0.9302
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A Q9QYJ6 PDE10_RAT Rattus norvegicus 3 0.9302
Chalcone--flavanone isomerase 1 P28012 CFI1_MEDSA Medicago sativa 3 0.9301
Chalcone--flavanone isomerase 1 P28012 CFI1_MEDSA Medicago sativa 3 0.9301
Chalcone--flavanone isomerase 1 P28012 CFI1_MEDSA Medicago sativa 3 0.9301
Chalcone--flavanone isomerase 1 P28012 CFI1_MEDSA Medicago sativa 3 0.9301
Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial Q33862 Q33862_ASCSU Ascaris suum 3 0.9299
Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial Q33862 Q33862_ASCSU Ascaris suum 3 0.9299
Acetolactate synthase, chloroplastic P17597 ILVB_ARATH Arabidopsis thaliana 3 0.9288
Acetolactate synthase, chloroplastic P17597 ILVB_ARATH Arabidopsis thaliana 3 0.9288
Queuine tRNA-ribosyltransferase P28720 TGT_ZYMMO Zymomonas mobilis subsp. mobilis 3 0.9280
Queuine tRNA-ribosyltransferase P28720 TGT_ZYMMO Zymomonas mobilis subsp. mobilis 3 0.9280
Serine/threonine-protein kinase 24 Q9Y6E0 STK24_HUMAN Homo sapiens 3 0.9266
Serine/threonine-protein kinase 24 Q9Y6E0 STK24_HUMAN Homo sapiens 3 0.9266
Heat shock protein HSP 90-alpha P07900 HS90A_HUMAN Homo sapiens 3 0.9261
Heat shock protein HSP 90-alpha P07900 HS90A_HUMAN Homo sapiens 3 0.9261
Serine/threonine-protein kinase 24 Q9Y6E0 STK24_HUMAN Homo sapiens 3 0.9245
Serine/threonine-protein kinase 24 Q9Y6E0 STK24_HUMAN Homo sapiens 3 0.9245
17beta-hydroxysteroid dehydrogenase O93874 O93874_COCLU Cochliobolus lunatus 3 0.9234
17beta-hydroxysteroid dehydrogenase O93874 O93874_COCLU Cochliobolus lunatus 3 0.9234
Lactoperoxidase P80025 PERL_BOVIN Bos taurus 3 0.9225
Lactoperoxidase P80025 PERL_BOVIN Bos taurus 3 0.9225
Thermolysin P00800 THER_BACTH Bacillus thermoproteolyticus 3 0.9207
Thermolysin P00800 THER_BACTH Bacillus thermoproteolyticus 3 0.9207
Flavonoid 3-O-glucosyltransferase A6XNC6 UGFGT_MEDTR Medicago truncatula 3 0.9199
Flavonoid 3-O-glucosyltransferase A6XNC6 UGFGT_MEDTR Medicago truncatula 3 0.9199
Queuine tRNA-ribosyltransferase P28720 TGT_ZYMMO Zymomonas mobilis subsp. mobilis 3 0.9183
Queuine tRNA-ribosyltransferase P28720 TGT_ZYMMO Zymomonas mobilis subsp. mobilis 3 0.9183
Pheromone-binding protein ASP1 Q9U9J6 Q9U9J6_APIME Apis mellifera 3 0.9181
Pheromone-binding protein ASP1 Q9U9J6 Q9U9J6_APIME Apis mellifera 3 0.9181
Beta-secretase 1 P56817 BACE1_HUMAN Homo sapiens 3 0.9155
Beta-secretase 1 P56817 BACE1_HUMAN Homo sapiens 3 0.9155
Gag-Pol polyprotein P04584 POL_HV2RO Human immunodeficiency virus type 2 subtype A 4 0.9148
Gag-Pol polyprotein P04584 POL_HV2RO Human immunodeficiency virus type 2 subtype A 4 0.9148
Nitric oxide synthase oxygenase O34453 NOSO_BACSU Bacillus subtilis 4 0.9145
Nitric oxide synthase oxygenase O34453 NOSO_BACSU Bacillus subtilis 4 0.9145
Transthyretin P02767 TTHY_RAT Rattus norvegicus 3 0.9143
Transthyretin P02767 TTHY_RAT Rattus norvegicus 3 0.9143
Bromodomain-containing protein 2 P25440 BRD2_HUMAN Homo sapiens 3 0.9117
Bromodomain-containing protein 2 P25440 BRD2_HUMAN Homo sapiens 3 0.9117
GTPase KRas P01116 RASK_HUMAN Homo sapiens 3 0.9116
GTPase KRas P01116 RASK_HUMAN Homo sapiens 3 0.9116
Glutathione S-transferase F2 P46422 GSTF2_ARATH Arabidopsis thaliana 3 0.9113
Glutathione S-transferase F2 P46422 GSTF2_ARATH Arabidopsis thaliana 3 0.9113
3',5'-cyclic-AMP phosphodiesterase 4D Q08499 PDE4D_HUMAN Homo sapiens 3 0.9112
3',5'-cyclic-AMP phosphodiesterase 4D Q08499 PDE4D_HUMAN Homo sapiens 3 0.9112
HTH-type transcriptional regulator TtgR Q9AIU0 TTGR_PSEPT Pseudomonas putida 3 0.9110
HTH-type transcriptional regulator TtgR Q9AIU0 TTGR_PSEPT Pseudomonas putida 3 0.9110
HTH-type transcriptional repressor PurR P0ACP7 PURR_ECOLI Escherichia coli 3 0.9108
HTH-type transcriptional repressor PurR P0ACP7 PURR_ECOLI Escherichia coli 3 0.9108
Mitogen-activated protein kinase 8 P45983 MK08_HUMAN Homo sapiens 3 0.9106
Mitogen-activated protein kinase 8 P45983 MK08_HUMAN Homo sapiens 3 0.9106
Mitogen-activated protein kinase 14 Q16539 MK14_HUMAN Homo sapiens 3 0.9066
Mitogen-activated protein kinase 14 Q16539 MK14_HUMAN Homo sapiens 3 0.9066
Beta-lactamase Q9L5C8 Q9L5C8_ECOLX Escherichia coli 3 0.9064
Beta-lactamase Q9L5C8 Q9L5C8_ECOLX Escherichia coli 3 0.9064
Prothrombin P00734 THRB_HUMAN Homo sapiens 3 0.9057
Prothrombin P00734 THRB_HUMAN Homo sapiens 3 0.9057
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial Q15119 PDK2_HUMAN Homo sapiens 3 0.9048
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial Q15119 PDK2_HUMAN Homo sapiens 3 0.9048
Nitric oxide synthase, inducible P35228 NOS2_HUMAN Homo sapiens 3 0.9044
Nitric oxide synthase, inducible P35228 NOS2_HUMAN Homo sapiens 3 0.9044
Pteridine reductase O76290 O76290_TRYBB Trypanosoma brucei brucei 3 0.9031
Pteridine reductase O76290 O76290_TRYBB Trypanosoma brucei brucei 3 0.9031
TGF-beta-activated kinase 1 and MAP3K7-binding protein 1 Q15750 TAB1_HUMAN Homo sapiens 3 0.9020
TGF-beta-activated kinase 1 and MAP3K7-binding protein 1 Q15750 TAB1_HUMAN Homo sapiens 3 0.9020
Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase Q9TQS6 DHDH_MACFA Macaca fascicularis 3 0.9017
Alpha-ketoglutarate-dependent dioxygenase FTO Q9C0B1 FTO_HUMAN Homo sapiens 3 0.9017
Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase Q9TQS6 DHDH_MACFA Macaca fascicularis 3 0.9017
Alpha-ketoglutarate-dependent dioxygenase FTO Q9C0B1 FTO_HUMAN Homo sapiens 3 0.9017
Ribosomal small subunit pseudouridine synthase A P0AA43 RSUA_ECOLI Escherichia coli 3 0.9015
Ribosomal small subunit pseudouridine synthase A P0AA43 RSUA_ECOLI Escherichia coli 3 0.9015
Dihydropteroate synthase Q81VW8 Q81VW8_BACAN Bacillus anthracis 4 0.9010
Dihydropteroate synthase Q81VW8 Q81VW8_BACAN Bacillus anthracis 4 0.9010
Epidermal growth factor receptor P00533 EGFR_HUMAN Homo sapiens 3 0.9004
Epidermal growth factor receptor P00533 EGFR_HUMAN Homo sapiens 3 0.9004
Steroid C26-monooxygenase P9WPP1 CP125_MYCTU Mycobacterium tuberculosis 3 0.9000
Steroid C26-monooxygenase P9WPP1 CP125_MYCTU Mycobacterium tuberculosis 3 0.9000
Heat shock protein HSP 90-alpha P07900 HS90A_HUMAN Homo sapiens 3 0.8994
Heat shock protein HSP 90-alpha P07900 HS90A_HUMAN Homo sapiens 3 0.8994
Phospholipase A2, major isoenzyme P00592 PA21B_PIG Sus scrofa 3 0.8982
Phospholipase A2, major isoenzyme P00592 PA21B_PIG Sus scrofa 3 0.8982
Prothrombin P00734 THRB_HUMAN Homo sapiens 3 0.8974
Prothrombin P00734 THRB_HUMAN Homo sapiens 3 0.8974
Dihydrofolate reductase P16184 DYR_PNECA Pneumocystis carinii 4 0.8963
Dihydrofolate reductase P16184 DYR_PNECA Pneumocystis carinii 4 0.8963
Tetracycline repressor protein class D P0ACT4 TETR4_ECOLX Escherichia coli 3 0.8962
Tetracycline repressor protein class D P0ACT4 TETR4_ECOLX Escherichia coli 3 0.8962
Chitinase Q54276 Q54276_SERMA Serratia marcescens 3 0.8958
Chitinase Q54276 Q54276_SERMA Serratia marcescens 3 0.8958
Endoplasmin P41148 ENPL_CANLF Canis lupus familiaris 3 0.8955
Endoplasmin P41148 ENPL_CANLF Canis lupus familiaris 3 0.8955
Nitric oxide synthase, inducible P29477 NOS2_MOUSE Mus musculus 4 0.8947
Nitric oxide synthase, inducible P29477 NOS2_MOUSE Mus musculus 4 0.8947
Dihydrofolate reductase P00381 DYR_LACCA Lacticaseibacillus casei 4 0.8942
Dihydrofolate reductase P00381 DYR_LACCA Lacticaseibacillus casei 4 0.8942
Dihydrofolate reductase P0A017 DYR_STAAU Staphylococcus aureus 4 0.8930
Dihydrofolate reductase P0A017 DYR_STAAU Staphylococcus aureus 4 0.8930
Fibroblast growth factor receptor 1 P11362 FGFR1_HUMAN Homo sapiens 3 0.8929
Dihydrofolate reductase O30463 O30463_MYCAV Mycobacterium avium 4 0.8929
Fibroblast growth factor receptor 1 P11362 FGFR1_HUMAN Homo sapiens 3 0.8929
Dihydrofolate reductase O30463 O30463_MYCAV Mycobacterium avium 4 0.8929
Histone deacetylase 4 P56524 HDAC4_HUMAN Homo sapiens 3 0.8926
Histone deacetylase 4 P56524 HDAC4_HUMAN Homo sapiens 3 0.8926
NADPH-dependent 7-cyano-7-deazaguanine reductase Q9KTK0 QUEF_VIBCH Vibrio cholerae serotype O1 3 0.8923
NADPH-dependent 7-cyano-7-deazaguanine reductase Q9KTK0 QUEF_VIBCH Vibrio cholerae serotype O1 3 0.8923
Mycocyclosin synthase P9WPP7 CP121_MYCTU Mycobacterium tuberculosis 3 0.8922
Mycocyclosin synthase P9WPP7 CP121_MYCTU Mycobacterium tuberculosis 3 0.8922
Mitogen-activated protein kinase 14 Q16539 MK14_HUMAN Homo sapiens 3 0.8920
Mitogen-activated protein kinase 14 Q16539 MK14_HUMAN Homo sapiens 3 0.8920
Dihydrofolate reductase P16184 DYR_PNECA Pneumocystis carinii 4 0.8914
Dihydrofolate reductase P16184 DYR_PNECA Pneumocystis carinii 4 0.8914
Prothrombin P00734 THRB_HUMAN Homo sapiens 3 0.8911
Prothrombin P00734 THRB_HUMAN Homo sapiens 3 0.8911
Glycogen synthase Q9V2J8 Q9V2J8_PYRAB Pyrococcus abyssi 3 0.8905
Glycogen synthase Q9V2J8 Q9V2J8_PYRAB Pyrococcus abyssi 3 0.8905
ATP-dependent molecular chaperone HSP82 P02829 HSP82_YEAST Saccharomyces cerevisiae 3 0.8903
ATP-dependent molecular chaperone HSP82 P02829 HSP82_YEAST Saccharomyces cerevisiae 3 0.8903
Steroid Delta-isomerase P00947 SDIS_COMTE Comamonas testosteroni 3 0.8900
Steroid Delta-isomerase P00947 SDIS_COMTE Comamonas testosteroni 3 0.8900
Epidermal growth factor receptor P00533 EGFR_HUMAN Homo sapiens 3 0.8899
Epidermal growth factor receptor P00533 EGFR_HUMAN Homo sapiens 3 0.8899
Glutamate receptor 2 P19491 GRIA2_RAT Rattus norvegicus 3 0.8898
Glutamate receptor 2 P19491 GRIA2_RAT Rattus norvegicus 3 0.8898
Dihydrofolate reductase P0A017 DYR_STAAU Staphylococcus aureus 4 0.8886
Dihydrofolate reductase P0A017 DYR_STAAU Staphylococcus aureus 4 0.8886
HTH-type transcriptional repressor PurR P0ACP7 PURR_ECOLI Escherichia coli 3 0.8870
HTH-type transcriptional repressor PurR P0ACP7 PURR_ECOLI Escherichia coli 3 0.8870
Cyclin-dependent kinase 2 P24941 CDK2_HUMAN Homo sapiens 4 0.8863
Cyclin-dependent kinase 2 P24941 CDK2_HUMAN Homo sapiens 4 0.8863
Beta-secretase 1 P56817 BACE1_HUMAN Homo sapiens 3 0.8861
Beta-secretase 1 P56817 BACE1_HUMAN Homo sapiens 3 0.8861
APH(2'')-Id O68183 O68183_ENTCA Enterococcus casseliflavus 4 0.8842
APH(2'')-Id O68183 O68183_ENTCA Enterococcus casseliflavus 4 0.8842
Thymidylate synthase P0A886 TYSY_ECO57 Escherichia coli O157:H7 3 0.8830
Thymidylate synthase P0A886 TYSY_ECO57 Escherichia coli O157:H7 3 0.8830
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 P04191 AT2A1_RABIT Oryctolagus cuniculus 3 0.8827
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 P04191 AT2A1_RABIT Oryctolagus cuniculus 3 0.8827
Proto-oncogene tyrosine-protein kinase Src P00523 SRC_CHICK Gallus gallus 3 0.8818
Proto-oncogene tyrosine-protein kinase Src P00523 SRC_CHICK Gallus gallus 3 0.8818
ATP-dependent molecular chaperone HSP82 P02829 HSP82_YEAST Saccharomyces cerevisiae 3 0.8812
ATP-dependent molecular chaperone HSP82 P02829 HSP82_YEAST Saccharomyces cerevisiae 3 0.8812
Glycogen synthase Q9V2J8 Q9V2J8_PYRAB Pyrococcus abyssi 3 0.8811
Glycogen synthase Q9V2J8 Q9V2J8_PYRAB Pyrococcus abyssi 3 0.8811
Cytohesin-2 Q99418 CYH2_HUMAN Homo sapiens 3 0.8810
Cytohesin-2 Q99418 CYH2_HUMAN Homo sapiens 3 0.8810
Endothiapepsin P11838 CARP_CRYPA Cryphonectria parasitica 3 0.8806
Endothiapepsin P11838 CARP_CRYPA Cryphonectria parasitica 3 0.8806
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial Q15119 PDK2_HUMAN Homo sapiens 4 0.8804
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial Q15119 PDK2_HUMAN Homo sapiens 4 0.8804
Dihydropteroate synthase Q81VW8 Q81VW8_BACAN Bacillus anthracis 4 0.8801
Aldo-keto reductase family 1 member B1 P15121 ALDR_HUMAN Homo sapiens 3 0.8801
Dihydropteroate synthase Q81VW8 Q81VW8_BACAN Bacillus anthracis 4 0.8801
Aldo-keto reductase family 1 member B1 P15121 ALDR_HUMAN Homo sapiens 3 0.8801
Cyclin-dependent kinase 2 P24941 CDK2_HUMAN Homo sapiens 3 0.8795
Cyclin-dependent kinase 2 P24941 CDK2_HUMAN Homo sapiens 3 0.8795
Methionine aminopeptidase 2 P50579 MAP2_HUMAN Homo sapiens 3 0.8769
Methionine aminopeptidase 2 P50579 MAP2_HUMAN Homo sapiens 3 0.8769
HTH-type transcriptional repressor PurR P0ACP7 PURR_ECOLI Escherichia coli 3 0.8767
HTH-type transcriptional repressor PurR P0ACP7 PURR_ECOLI Escherichia coli 3 0.8767
Protein S100-A13 Q99584 S10AD_HUMAN Homo sapiens 3 0.8765
Protein S100-A13 Q99584 S10AD_HUMAN Homo sapiens 3 0.8765
Mycinamicin III 3''-O-methyltransferase Q49492 MYCF_MICGR Micromonospora griseorubida 2 0.8761
Mycinamicin III 3''-O-methyltransferase Q49492 MYCF_MICGR Micromonospora griseorubida 2 0.8761
Serine/threonine-protein kinase pim-1 P11309 PIM1_HUMAN Homo sapiens 3 0.8755
Serine/threonine-protein kinase pim-1 P11309 PIM1_HUMAN Homo sapiens 3 0.8755
Glycogen synthase kinase-3 beta P49841 GSK3B_HUMAN Homo sapiens 3 0.8754
Glycogen synthase kinase-3 beta P49841 GSK3B_HUMAN Homo sapiens 3 0.8754
Purine nucleoside phosphorylase DeoD-type P0ABP9 DEOD_ECO57 Escherichia coli O157:H7 3 0.8750
Purine nucleoside phosphorylase DeoD-type P0ABP9 DEOD_ECO57 Escherichia coli O157:H7 3 0.8750
Pteridine reductase 1 Q01782 PTR1_LEIMA Leishmania major 4 0.8749
Pteridine reductase 1 Q01782 PTR1_LEIMA Leishmania major 4 0.8749
Carbonyl reductase [NADPH] 1 P16152 CBR1_HUMAN Homo sapiens 3 0.8746
Carbonyl reductase [NADPH] 1 P16152 CBR1_HUMAN Homo sapiens 3 0.8746
Isoliquiritigenin 2'-O-methyltransferase P93324 CHOMT_MEDSA Medicago sativa 4 0.8739
Isoliquiritigenin 2'-O-methyltransferase P93324 CHOMT_MEDSA Medicago sativa 4 0.8739
Carbonyl reductase [NADPH] 1 P16152 CBR1_HUMAN Homo sapiens 3 0.8718
Carbonyl reductase [NADPH] 1 P16152 CBR1_HUMAN Homo sapiens 3 0.8718
Heat shock protein HSP 90-alpha P07900 HS90A_HUMAN Homo sapiens 3 0.8715
Heat shock protein HSP 90-alpha P07900 HS90A_HUMAN Homo sapiens 3 0.8715
Mitogen-activated protein kinase 14 Q16539 MK14_HUMAN Homo sapiens 3 0.8707
Mitogen-activated protein kinase 14 Q16539 MK14_HUMAN Homo sapiens 3 0.8707
Dihydrofolate reductase Q83AB2 Q83AB2_COXBU Coxiella burnetii 4 0.8684
Dihydrofolate reductase Q83AB2 Q83AB2_COXBU Coxiella burnetii 4 0.8684
5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase Q81LL4 MTNN_BACAN Bacillus anthracis 3 0.8668
5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase Q81LL4 MTNN_BACAN Bacillus anthracis 3 0.8668
Dihydrofolate reductase Q81R22 Q81R22_BACAN Bacillus anthracis 4 0.8647
Dihydrofolate reductase Q81R22 Q81R22_BACAN Bacillus anthracis 4 0.8647
ATP-dependent molecular chaperone HSP82 P02829 HSP82_YEAST Saccharomyces cerevisiae 3 0.8646
ATP-dependent molecular chaperone HSP82 P02829 HSP82_YEAST Saccharomyces cerevisiae 3 0.8646
Epidermal growth factor receptor P00533 EGFR_HUMAN Homo sapiens 3 0.8637
Epidermal growth factor receptor P00533 EGFR_HUMAN Homo sapiens 3 0.8637
Mitogen-activated protein kinase 14 Q16539 MK14_HUMAN Homo sapiens 3 0.8635
Peroxisome proliferator-activated receptor gamma P37231 PPARG_HUMAN Homo sapiens 3 0.8635
Mitogen-activated protein kinase 14 Q16539 MK14_HUMAN Homo sapiens 3 0.8635
Peroxisome proliferator-activated receptor gamma P37231 PPARG_HUMAN Homo sapiens 3 0.8635
Endothiapepsin P11838 CARP_CRYPA Cryphonectria parasitica 4 0.8634
Endothiapepsin P11838 CARP_CRYPA Cryphonectria parasitica 4 0.8634
Mitogen-activated protein kinase 14 Q16539 MK14_HUMAN Homo sapiens 4 0.8626
Mitogen-activated protein kinase 14 Q16539 MK14_HUMAN Homo sapiens 4 0.8626
Glycogen phosphorylase, muscle form P00489 PYGM_RABIT Oryctolagus cuniculus 3 0.8624
Glycogen phosphorylase, muscle form P00489 PYGM_RABIT Oryctolagus cuniculus 3 0.8624
Purine nucleoside phosphorylase DeoD-type Q5EEL8 DEOD_BACCE Bacillus cereus 3 0.8622
Purine nucleoside phosphorylase DeoD-type Q5EEL8 DEOD_BACCE Bacillus cereus 3 0.8622
Epidermal growth factor receptor P00533 EGFR_HUMAN Homo sapiens 3 0.8610
Epidermal growth factor receptor P00533 EGFR_HUMAN Homo sapiens 3 0.8610
Pheromone-binding protein ASP1 Q9U9J6 Q9U9J6_APIME Apis mellifera 3 0.8608
Pheromone-binding protein ASP1 Q9U9J6 Q9U9J6_APIME Apis mellifera 3 0.8608
Gag-Pol polyprotein P12497 POL_HV1N5 Human immunodeficiency virus type 1 group M subtype B 3 0.8593
Gag-Pol polyprotein P12497 POL_HV1N5 Human immunodeficiency virus type 1 group M subtype B 3 0.8593
Tyrosine-protein kinase JAK2 O60674 JAK2_HUMAN Homo sapiens 3 0.8587
Tyrosine-protein kinase JAK2 O60674 JAK2_HUMAN Homo sapiens 3 0.8587
Acetolactate synthase catalytic subunit, mitochondrial P07342 ILVB_YEAST Saccharomyces cerevisiae 3 0.8585
Acetolactate synthase catalytic subunit, mitochondrial P07342 ILVB_YEAST Saccharomyces cerevisiae 3 0.8585
Heat shock protein HSP 90-alpha P07900 HS90A_HUMAN Homo sapiens 3 0.8581
Heat shock protein HSP 90-alpha P07900 HS90A_HUMAN Homo sapiens 3 0.8581
Nicotinamide phosphoribosyltransferase P43490 NAMPT_HUMAN Homo sapiens 3 0.8578
Nicotinamide phosphoribosyltransferase P43490 NAMPT_HUMAN Homo sapiens 3 0.8578
Peptidyl-prolyl cis-trans isomerase FKBP1A P62942 FKB1A_HUMAN Homo sapiens 3 0.8577
Peptidyl-prolyl cis-trans isomerase FKBP1A P62942 FKB1A_HUMAN Homo sapiens 3 0.8577
Dihydrofolate reductase Q81R22 Q81R22_BACAN Bacillus anthracis 4 0.8568
Dihydrofolate reductase Q81R22 Q81R22_BACAN Bacillus anthracis 4 0.8568
17beta-hydroxysteroid dehydrogenase O93874 O93874_COCLU Cochliobolus lunatus 3 0.8559
17beta-hydroxysteroid dehydrogenase O93874 O93874_COCLU Cochliobolus lunatus 3 0.8559
Mycinamicin III 3''-O-methyltransferase Q49492 MYCF_MICGR Micromonospora griseorubida 2 0.8552
Mycinamicin III 3''-O-methyltransferase Q49492 MYCF_MICGR Micromonospora griseorubida 2 0.8552
Putative ketoacyl reductase P16544 ACT3_STRCO Streptomyces coelicolor / M145) 3 0.8537
Putative ketoacyl reductase P16544 ACT3_STRCO Streptomyces coelicolor / M145) 3 0.8537
Dihydrofolate reductase Q81R22 Q81R22_BACAN Bacillus anthracis 4 0.8533
Dihydrofolate reductase Q81R22 Q81R22_BACAN Bacillus anthracis 4 0.8533
Decaprenylphosphoryl-beta-D-ribose oxidase I6X8C4 I6X8C4_MYCTU Mycobacterium tuberculosis 3 0.8526
Decaprenylphosphoryl-beta-D-ribose oxidase I6X8C4 I6X8C4_MYCTU Mycobacterium tuberculosis 3 0.8526
Pyruvate kinase PKM P14618 KPYM_HUMAN Homo sapiens 3 0.8523
Pyruvate kinase PKM P14618 KPYM_HUMAN Homo sapiens 3 0.8523
Caspase-6 P55212 CASP6_HUMAN Homo sapiens 3 0.8518
Caspase-6 P55212 CASP6_HUMAN Homo sapiens 3 0.8518
Cytochrome P450 1A1 P04798 CP1A1_HUMAN Homo sapiens 3 0.8514
Cytochrome P450 1A1 P04798 CP1A1_HUMAN Homo sapiens 3 0.8514
Protoporphyrinogen oxidase P50336 PPOX_HUMAN Homo sapiens 3 0.8504
Protoporphyrinogen oxidase P50336 PPOX_HUMAN Homo sapiens 3 0.8504
Prothrombin P00734 THRB_HUMAN Homo sapiens 3 0.8488
Prothrombin P00734 THRB_HUMAN Homo sapiens 3 0.8488
Chalcone--flavanone isomerase 1 P28012 CFI1_MEDSA Medicago sativa 4 0.8484
Chalcone--flavanone isomerase 1 P28012 CFI1_MEDSA Medicago sativa 4 0.8484
Beta-adrenergic receptor kinase 1 P25098 ARBK1_HUMAN Homo sapiens 3 0.8480
Beta-adrenergic receptor kinase 1 P25098 ARBK1_HUMAN Homo sapiens 3 0.8480
Beta-lactamase Q9L5C8 Q9L5C8_ECOLX Escherichia coli 3 0.8480
Beta-lactamase Q9L5C8 Q9L5C8_ECOLX Escherichia coli 3 0.8480
IOMT 3 Q06YR3 Q06YR3_MEDTR Medicago truncatula 4 0.8476
IOMT 3 Q06YR3 Q06YR3_MEDTR Medicago truncatula 4 0.8476
L-lactate dehydrogenase A chain P04642 LDHA_RAT Rattus norvegicus 3 0.8475
L-lactate dehydrogenase A chain P04642 LDHA_RAT Rattus norvegicus 3 0.8475
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial Q15119 PDK2_HUMAN Homo sapiens 3 0.8474
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial Q15119 PDK2_HUMAN Homo sapiens 3 0.8474
Cathepsin S P25774 CATS_HUMAN Homo sapiens 3 0.8465
Cathepsin S P25774 CATS_HUMAN Homo sapiens 3 0.8465
Albumin P02768 ALBU_HUMAN Homo sapiens 3 0.8463
Albumin P02768 ALBU_HUMAN Homo sapiens 3 0.8463
Endothiapepsin P11838 CARP_CRYPA Cryphonectria parasitica 3 0.8460
Endothiapepsin P11838 CARP_CRYPA Cryphonectria parasitica 3 0.8460
Purine nucleoside phosphorylase DeoD-type P0ABP8 DEOD_ECOLI Escherichia coli 3 0.8459
Purine nucleoside phosphorylase DeoD-type P0ABP8 DEOD_ECOLI Escherichia coli 3 0.8459
Stromelysin-1 P08254 MMP3_HUMAN Homo sapiens 3 0.8456
Stromelysin-1 P08254 MMP3_HUMAN Homo sapiens 3 0.8456
Carbonic anhydrase 2 P00918 CAH2_HUMAN Homo sapiens 3 0.8452
Carbonic anhydrase 2 P00918 CAH2_HUMAN Homo sapiens 3 0.8452
Protoporphyrinogen oxidase P50336 PPOX_HUMAN Homo sapiens 3 0.8452
Protoporphyrinogen oxidase P50336 PPOX_HUMAN Homo sapiens 3 0.8452
Major pollen allergen Bet v 1-A P15494 BEV1A_BETPN Betula pendula 3 0.8449
Major pollen allergen Bet v 1-A P15494 BEV1A_BETPN Betula pendula 3 0.8449
Dihydropteroate synthase Q81VW8 Q81VW8_BACAN Bacillus anthracis 3 0.8426
Dihydropteroate synthase Q81VW8 Q81VW8_BACAN Bacillus anthracis 3 0.8426
Heat shock protein HSP 90-alpha P07900 HS90A_HUMAN Homo sapiens 3 0.8425
Heat shock protein HSP 90-alpha P07900 HS90A_HUMAN Homo sapiens 3 0.8425
Mitogen-activated protein kinase 14 Q16539 MK14_HUMAN Homo sapiens 3 0.8417
Mitogen-activated protein kinase 14 Q16539 MK14_HUMAN Homo sapiens 3 0.8417
Gag-Pol polyprotein P04585 POL_HV1H2 Human immunodeficiency virus type 1 group M subtype B 3 0.8413
Gag-Pol polyprotein P04585 POL_HV1H2 Human immunodeficiency virus type 1 group M subtype B 3 0.8413
Na(+):neurotransmitter symporter (Snf family) O67854 O67854_AQUAE Aquifex aeolicus 3 0.8412
Na(+):neurotransmitter symporter (Snf family) O67854 O67854_AQUAE Aquifex aeolicus 3 0.8412
Serine/threonine-protein kinase Chk1 O14757 CHK1_HUMAN Homo sapiens 3 0.8407
Serine/threonine-protein kinase Chk1 O14757 CHK1_HUMAN Homo sapiens 3 0.8407
Nodulin-13 P93330 NOD13_MEDTR Medicago truncatula 3 0.8400
Nodulin-13 P93330 NOD13_MEDTR Medicago truncatula 3 0.8400
Purine nucleoside phosphorylase DeoD-type P0ABP9 DEOD_ECO57 Escherichia coli O157:H7 3 0.8398
Purine nucleoside phosphorylase DeoD-type P0ABP9 DEOD_ECO57 Escherichia coli O157:H7 3 0.8398
Bifunctional epoxide hydrolase 2 P34913 HYES_HUMAN Homo sapiens 4 0.8398
Bifunctional epoxide hydrolase 2 P34913 HYES_HUMAN Homo sapiens 4 0.8398
HTH-type transcriptional repressor PurR P0ACP7 PURR_ECOLI Escherichia coli 3 0.8396
HTH-type transcriptional repressor PurR P0ACP7 PURR_ECOLI Escherichia coli 3 0.8396
Toxoflavin degrading enzyme E3SET7 E3SET7_PAEPO Paenibacillus polymyxa 3 0.8390
Toxoflavin degrading enzyme E3SET7 E3SET7_PAEPO Paenibacillus polymyxa 3 0.8390
Heat shock protein HSP 90-alpha P07900 HS90A_HUMAN Homo sapiens 3 0.8385
Heat shock protein HSP 90-alpha P07900 HS90A_HUMAN Homo sapiens 3 0.8385
Carbonic anhydrase 2 P00918 CAH2_HUMAN Homo sapiens 3 0.8384
Carbonic anhydrase 2 P00918 CAH2_HUMAN Homo sapiens 3 0.8384
Purine nucleoside phosphorylase DeoD-type O34925 DEOD_BACSU Bacillus subtilis 3 0.8383
Purine nucleoside phosphorylase DeoD-type O34925 DEOD_BACSU Bacillus subtilis 3 0.8383
Purine nucleoside phosphorylase Q8I3X4 Q8I3X4_PLAF7 Plasmodium falciparum 3 0.8378
Purine nucleoside phosphorylase Q8I3X4 Q8I3X4_PLAF7 Plasmodium falciparum 3 0.8378
Kinesin-like protein KIF11 P52732 KIF11_HUMAN Homo sapiens 3 0.8377
Kinesin-like protein KIF11 P52732 KIF11_HUMAN Homo sapiens 3 0.8377
Cyclin-dependent kinase 2 P24941 CDK2_HUMAN Homo sapiens 3 0.8373
Cyclin-dependent kinase 2 P24941 CDK2_HUMAN Homo sapiens 3 0.8373
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A Q9Y233 PDE10_HUMAN Homo sapiens 3 0.8362
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A Q9Y233 PDE10_HUMAN Homo sapiens 3 0.8362
Riboflavin synthase P0AFU8 RISA_ECOLI Escherichia coli 4 0.8350
Riboflavin synthase P0AFU8 RISA_ECOLI Escherichia coli 4 0.8350
Pheromone-binding protein ASP1 Q9U9J6 Q9U9J6_APIME Apis mellifera 3 0.8344
Pheromone-binding protein ASP1 Q9U9J6 Q9U9J6_APIME Apis mellifera 3 0.8344
Dihydrofolate reductase P00381 DYR_LACCA Lacticaseibacillus casei 4 0.8341
Dihydrofolate reductase P00381 DYR_LACCA Lacticaseibacillus casei 4 0.8341
cytokinin dehydrogenase E3T1W8 E3T1W8_MAIZE Zea mays 3 0.8329
cytokinin dehydrogenase E3T1W8 E3T1W8_MAIZE Zea mays 3 0.8329
Purine nucleoside phosphorylase DeoD-type Q5EEL8 DEOD_BACCE Bacillus cereus 3 0.8326
Purine nucleoside phosphorylase DeoD-type Q5EEL8 DEOD_BACCE Bacillus cereus 3 0.8326
Queuine tRNA-ribosyltransferase P28720 TGT_ZYMMO Zymomonas mobilis subsp. mobilis 3 0.8324
Queuine tRNA-ribosyltransferase P28720 TGT_ZYMMO Zymomonas mobilis subsp. mobilis 3 0.8324
Gag-Pol polyprotein O12158 POL_HV192 Human immunodeficiency virus type 1 group M subtype C 3 0.8322
Gag-Pol polyprotein O12158 POL_HV192 Human immunodeficiency virus type 1 group M subtype C 3 0.8322
Tetracycline repressor protein class H P51561 TETR8_PASMD Pasteurella multocida 3 0.8304
Tetracycline repressor protein class H P51561 TETR8_PASMD Pasteurella multocida 3 0.8304
Heat shock protein HSP 90-alpha P07900 HS90A_HUMAN Homo sapiens 3 0.8304
Heat shock protein HSP 90-alpha P07900 HS90A_HUMAN Homo sapiens 3 0.8304
Tetracycline repressor protein class D P0ACT4 TETR4_ECOLX Escherichia coli 3 0.8300
Tetracycline repressor protein class D P0ACT4 TETR4_ECOLX Escherichia coli 3 0.8300
cAMP-dependent protein kinase type I-alpha regulatory subunit P00514 KAP0_BOVIN Bos taurus 3 0.8294
cAMP-dependent protein kinase type I-alpha regulatory subunit P00514 KAP0_BOVIN Bos taurus 3 0.8294
Carbonyl reductase [NADPH] 1 P16152 CBR1_HUMAN Homo sapiens 3 0.8284
Carbonyl reductase [NADPH] 1 P16152 CBR1_HUMAN Homo sapiens 3 0.8284
Soluble acetylcholine receptor Q8WSF8 Q8WSF8_APLCA Aplysia californica 3 0.8283
Soluble acetylcholine receptor Q8WSF8 Q8WSF8_APLCA Aplysia californica 3 0.8283
Pheromone-binding protein ASP1 Q9U9J6 Q9U9J6_APIME Apis mellifera 3 0.8277
Pheromone-binding protein ASP1 Q9U9J6 Q9U9J6_APIME Apis mellifera 3 0.8277
Isoflavone 4'-O-methyltransferase Q29U70 I4OMT_MEDTR Medicago truncatula 4 0.8267
Isoflavone 4'-O-methyltransferase Q29U70 I4OMT_MEDTR Medicago truncatula 4 0.8267
Nucleoside 2-deoxyribosyltransferase Q8RLY5 Q8RLY5_LACHE Lactobacillus helveticus 3 0.8267
Nucleoside 2-deoxyribosyltransferase Q8RLY5 Q8RLY5_LACHE Lactobacillus helveticus 3 0.8267
Prothrombin P00734 THRB_HUMAN Homo sapiens 3 0.8257
Epidermal growth factor receptor P00533 EGFR_HUMAN Homo sapiens 3 0.8257
Prothrombin P00734 THRB_HUMAN Homo sapiens 3 0.8257
Epidermal growth factor receptor P00533 EGFR_HUMAN Homo sapiens 3 0.8257
Nitric oxide synthase 3 P29474 NOS3_HUMAN Homo sapiens 3 0.8252
Nitric oxide synthase 3 P29474 NOS3_HUMAN Homo sapiens 3 0.8252
Heat shock protein HSP 90-alpha P07900 HS90A_HUMAN Homo sapiens 3 0.8249
Heat shock protein HSP 90-alpha P07900 HS90A_HUMAN Homo sapiens 3 0.8249
Matrilysin P09237 MMP7_HUMAN Homo sapiens 3 0.8248
Matrilysin P09237 MMP7_HUMAN Homo sapiens 3 0.8248
Gag-Pol polyprotein P03367 POL_HV1BR Human immunodeficiency virus type 1 group M subtype B 3 0.8245
Gag-Pol polyprotein P03367 POL_HV1BR Human immunodeficiency virus type 1 group M subtype B 3 0.8245
3',5'-cyclic-AMP phosphodiesterase 4D Q08499 PDE4D_HUMAN Homo sapiens 3 0.8224
3',5'-cyclic-AMP phosphodiesterase 4D Q08499 PDE4D_HUMAN Homo sapiens 3 0.8224
Pteridine reductase 1 Q01782 PTR1_LEIMA Leishmania major 3 0.8219
Pteridine reductase 1 Q01782 PTR1_LEIMA Leishmania major 3 0.8219
Nitric oxide synthase, inducible P29477 NOS2_MOUSE Mus musculus 3 0.8210
Nitric oxide synthase, inducible P29477 NOS2_MOUSE Mus musculus 3 0.8210
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase P62617 ISPF_ECOLI Escherichia coli 3 0.8189
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase P62617 ISPF_ECOLI Escherichia coli 3 0.8189
Soluble cytochrome b562 P0ABE7 C562_ECOLX Escherichia coli 3 0.8173
Soluble cytochrome b562 P0ABE7 C562_ECOLX Escherichia coli 3 0.8173
Mitogen-activated protein kinase 10 P53779 MK10_HUMAN Homo sapiens 3 0.8170
Mitogen-activated protein kinase 10 P53779 MK10_HUMAN Homo sapiens 3 0.8170
Succinate dehydrogenase flavoprotein subunit P0AC41 SDHA_ECOLI Escherichia coli 3 0.8166
Succinate dehydrogenase flavoprotein subunit P0AC41 SDHA_ECOLI Escherichia coli 3 0.8166
Cyclic dipeptide N-prenyltransferase D1D8L6 D1D8L6_ASPFM Neosartorya fumigata 3 0.8161
Cyclic dipeptide N-prenyltransferase D1D8L6 D1D8L6_ASPFM Neosartorya fumigata 3 0.8161
Enoyl-ACP reductase Q9BJJ9 Q9BJJ9_PLAFA Plasmodium falciparum 3 0.8156
Enoyl-ACP reductase Q9BJJ9 Q9BJJ9_PLAFA Plasmodium falciparum 3 0.8156
Glycogen phosphorylase, muscle form P00489 PYGM_RABIT Oryctolagus cuniculus 3 0.8142
Glycogen phosphorylase, muscle form P00489 PYGM_RABIT Oryctolagus cuniculus 3 0.8142
Activin receptor type-1 Q04771 ACVR1_HUMAN Homo sapiens 3 0.8139
Activin receptor type-1 Q04771 ACVR1_HUMAN Homo sapiens 3 0.8139
Mycocyclosin synthase P9WPP7 CP121_MYCTU Mycobacterium tuberculosis 3 0.8138
Mycocyclosin synthase P9WPP7 CP121_MYCTU Mycobacterium tuberculosis 3 0.8138
Neocarzinostatin P0A3R9 NCZS_STRCZ Streptomyces carzinostaticus 3 0.8127
Neocarzinostatin P0A3R9 NCZS_STRCZ Streptomyces carzinostaticus 3 0.8127
Prothrombin P00734 THRB_HUMAN Homo sapiens 3 0.8123
Prothrombin P00734 THRB_HUMAN Homo sapiens 3 0.8123
Putative ketoacyl reductase P16544 ACT3_STRCO Streptomyces coelicolor / M145) 3 0.8121
Putative ketoacyl reductase P16544 ACT3_STRCO Streptomyces coelicolor / M145) 3 0.8121
Proto-oncogene tyrosine-protein kinase Src P12931 SRC_HUMAN Homo sapiens 3 0.8101
Proto-oncogene tyrosine-protein kinase Src P12931 SRC_HUMAN Homo sapiens 3 0.8101
Adenylate cyclase 2 A0A2U2H3Y1 A0A384LKY8_YERPE Yersinia pestis 3 0.8096
HTH-type transcriptional regulator EthR P9WMC1 ETHR_MYCTU Mycobacterium tuberculosis 3 0.8096
Adenylate cyclase 2 A0A2U2H3Y1 A0A384LKY8_YERPE Yersinia pestis 3 0.8096
HTH-type transcriptional regulator EthR P9WMC1 ETHR_MYCTU Mycobacterium tuberculosis 3 0.8096
Heat shock protein HSP 90-alpha P07900 HS90A_HUMAN Homo sapiens 3 0.8094
Heat shock protein HSP 90-alpha P07900 HS90A_HUMAN Homo sapiens 3 0.8094
Anthocyanidin 3-O-glucosyltransferase UFGT P51094 UFOG_VITVI Vitis vinifera 3 0.8089
Anthocyanidin 3-O-glucosyltransferase UFGT P51094 UFOG_VITVI Vitis vinifera 3 0.8089
Hexokinase-4 P35557 HXK4_HUMAN Homo sapiens 3 0.8080
Hexokinase-4 P35557 HXK4_HUMAN Homo sapiens 3 0.8080
Mitogen-activated protein kinase 14 Q16539 MK14_HUMAN Homo sapiens 3 0.8076
Mitogen-activated protein kinase 14 Q16539 MK14_HUMAN Homo sapiens 3 0.8076
Glycogen synthase kinase-3 beta P49841 GSK3B_HUMAN Homo sapiens 3 0.8075
Glycogen synthase kinase-3 beta P49841 GSK3B_HUMAN Homo sapiens 3 0.8075
Purine nucleoside phosphorylase DeoD-type P0ABP8 DEOD_ECOLI Escherichia coli 3 0.8073
Purine nucleoside phosphorylase DeoD-type P0ABP8 DEOD_ECOLI Escherichia coli 3 0.8073
Phospholipase A2, major isoenzyme P00592 PA21B_PIG Sus scrofa 3 0.8061
Phospholipase A2, major isoenzyme P00592 PA21B_PIG Sus scrofa 3 0.8061
Beta-secretase 1 P56817 BACE1_HUMAN Homo sapiens 3 0.8053
Beta-secretase 1 P56817 BACE1_HUMAN Homo sapiens 3 0.8053
Glucose-1-phosphate thymidylyltransferase Q9HU22 Q9HU22_PSEAE Pseudomonas aeruginosa 3 0.8046
Glucose-1-phosphate thymidylyltransferase Q9HU22 Q9HU22_PSEAE Pseudomonas aeruginosa 3 0.8046
Fatty acid-binding protein, intestinal P12104 FABPI_HUMAN Homo sapiens 3 0.8038
Fatty acid-binding protein, intestinal P12104 FABPI_HUMAN Homo sapiens 3 0.8038
Serine/threonine-protein kinase pim-1 P11309 PIM1_HUMAN Homo sapiens 3 0.8037
Serine/threonine-protein kinase pim-1 P11309 PIM1_HUMAN Homo sapiens 3 0.8037
Succinate dehydrogenase flavoprotein subunit P0AC41 SDHA_ECOLI Escherichia coli 3 0.8034
Succinate dehydrogenase flavoprotein subunit P0AC41 SDHA_ECOLI Escherichia coli 3 0.8034
Cyclin-dependent kinase 2 P24941 CDK2_HUMAN Homo sapiens 3 0.8034
Cyclin-dependent kinase 2 P24941 CDK2_HUMAN Homo sapiens 3 0.8034
Heat shock protein HSP 90-alpha P07900 HS90A_HUMAN Homo sapiens 3 0.8023
Heat shock protein HSP 90-alpha P07900 HS90A_HUMAN Homo sapiens 3 0.8023
cGMP-dependent protein kinase 2 Q13237 KGP2_HUMAN Homo sapiens 3 0.8023
cGMP-dependent protein kinase 2 Q13237 KGP2_HUMAN Homo sapiens 3 0.8023
Sulfide-quinone reductase B7JBP8 SQRD_ACIF2 Acidithiobacillus ferrooxidans) 3 0.8011
Sulfide-quinone reductase B7JBP8 SQRD_ACIF2 Acidithiobacillus ferrooxidans) 3 0.8011
Gag-Pol polyprotein P03367 POL_HV1BR Human immunodeficiency virus type 1 group M subtype B 3 0.8009
Gag-Pol polyprotein P03367 POL_HV1BR Human immunodeficiency virus type 1 group M subtype B 3 0.8009
Mitogen-activated protein kinase 14 Q16539 MK14_HUMAN Homo sapiens 3 0.8005
Mitogen-activated protein kinase 14 Q16539 MK14_HUMAN Homo sapiens 3 0.8005
Proton-gated ion channel Q7NDN8 GLIC_GLOVI Gloeobacter violaceus 3 0.7999
Proton-gated ion channel Q7NDN8 GLIC_GLOVI Gloeobacter violaceus 3 0.7999
Phytohormone-binding protein CSBP A0A1S3THR8 PHBP_VIGRR Vigna radiata var. radiata 3 0.7992
Phytohormone-binding protein CSBP A0A1S3THR8 PHBP_VIGRR Vigna radiata var. radiata 3 0.7992
Vitamin D3 receptor A Q9PTN2 VDRA_DANRE Danio rerio 4 0.7989
Vitamin D3 receptor A Q9PTN2 VDRA_DANRE Danio rerio 4 0.7989
Nuclear receptor subfamily 1 group I member 2 O75469 NR1I2_HUMAN Homo sapiens 3 0.7988
Nuclear receptor subfamily 1 group I member 2 O75469 NR1I2_HUMAN Homo sapiens 3 0.7988
Dipeptidyl peptidase 4 P27487 DPP4_HUMAN Homo sapiens 3 0.7977
Peptidyl-prolyl cis-trans isomerase FKBP1A P62942 FKB1A_HUMAN Homo sapiens 4 0.7977
Dipeptidyl peptidase 4 P27487 DPP4_HUMAN Homo sapiens 3 0.7977
Peptidyl-prolyl cis-trans isomerase FKBP1A P62942 FKB1A_HUMAN Homo sapiens 4 0.7977
Enoyl-ACP reductase Q9BH77 Q9BH77_PLAFA Plasmodium falciparum 3 0.7976
Enoyl-ACP reductase Q9BH77 Q9BH77_PLAFA Plasmodium falciparum 3 0.7976
Cytokinin dehydrogenase 1 Q9T0N8 CKX1_MAIZE Zea mays 3 0.7974
Cytokinin dehydrogenase 1 Q9T0N8 CKX1_MAIZE Zea mays 3 0.7974
Adenylate cyclase type 5 P30803 ADCY5_CANLF Canis lupus familiaris 4 0.7968
Adenylate cyclase type 5 P30803 ADCY5_CANLF Canis lupus familiaris 4 0.7968
Peptidyl-prolyl cis-trans isomerase FKBP5 Q13451 FKBP5_HUMAN Homo sapiens 4 0.7956
Peptidyl-prolyl cis-trans isomerase FKBP5 Q13451 FKBP5_HUMAN Homo sapiens 4 0.7956
Pyridoxal kinase P82197 PDXK_SHEEP Ovis aries 3 0.7955
Pyridoxal kinase P82197 PDXK_SHEEP Ovis aries 3 0.7955
Heat shock protein HSP 90-alpha P07900 HS90A_HUMAN Homo sapiens 3 0.7939
Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial Q0QF01 SDHA_PIG Sus scrofa 3 0.7939
Heat shock protein HSP 90-alpha P07900 HS90A_HUMAN Homo sapiens 3 0.7939
Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial Q0QF01 SDHA_PIG Sus scrofa 3 0.7939
Pyridoxal kinase P82197 PDXK_SHEEP Ovis aries 3 0.7934
Pyridoxal kinase P82197 PDXK_SHEEP Ovis aries 3 0.7934
Single-strand selective monofunctional uracil DNA glycosylase Q9YGN6 SMUG1_XENLA Xenopus laevis 4 0.7933
Single-strand selective monofunctional uracil DNA glycosylase Q9YGN6 SMUG1_XENLA Xenopus laevis 4 0.7933
Isoflavone-7-O-methyltransferase 8 O24529 7OMT8_MEDSA Medicago sativa 4 0.7925
Isoflavone-7-O-methyltransferase 8 O24529 7OMT8_MEDSA Medicago sativa 4 0.7925
Ephrin type-B receptor 4 P54760 EPHB4_HUMAN Homo sapiens 3 0.7913
Cyclin-dependent kinase 2 P24941 CDK2_HUMAN Homo sapiens 3 0.7913
Cyclin-dependent kinase 2 P24941 CDK2_HUMAN Homo sapiens 3 0.7913
Ephrin type-B receptor 4 P54760 EPHB4_HUMAN Homo sapiens 3 0.7913
Pteridine reductase 1 Q01782 PTR1_LEIMA Leishmania major 4 0.7912
Pteridine reductase 1 Q01782 PTR1_LEIMA Leishmania major 4 0.7912
Gag-Pol polyprotein P04584 POL_HV2RO Human immunodeficiency virus type 2 subtype A 3 0.7910
Gag-Pol polyprotein P04584 POL_HV2RO Human immunodeficiency virus type 2 subtype A 3 0.7910
Heat shock protein HSP 90-alpha P07900 HS90A_HUMAN Homo sapiens 3 0.7909
Heat shock protein HSP 90-alpha P07900 HS90A_HUMAN Homo sapiens 3 0.7909
Dihydrofolate reductase P00374 DYR_HUMAN Homo sapiens 3 0.7897
Dihydrofolate reductase P00374 DYR_HUMAN Homo sapiens 3 0.7897
Endothiapepsin P11838 CARP_CRYPA Cryphonectria parasitica 3 0.7892
Endothiapepsin P11838 CARP_CRYPA Cryphonectria parasitica 3 0.7892
Histone-lysine N-methyltransferase SETD7 Q8WTS6 SETD7_HUMAN Homo sapiens 3 0.7883
Histone-lysine N-methyltransferase SETD7 Q8WTS6 SETD7_HUMAN Homo sapiens 3 0.7883
Cyclin-dependent kinase 2 P24941 CDK2_HUMAN Homo sapiens 4 0.7879
Cyclin-dependent kinase 2 P24941 CDK2_HUMAN Homo sapiens 4 0.7879
HTH-type transcriptional repressor PurR P0ACP7 PURR_ECOLI Escherichia coli 4 0.7875
HTH-type transcriptional repressor PurR P0ACP7 PURR_ECOLI Escherichia coli 4 0.7875
Dual specificity mitogen-activated protein kinase kinase 1 Q02750 MP2K1_HUMAN Homo sapiens 3 0.7864
Dual specificity mitogen-activated protein kinase kinase 1 Q02750 MP2K1_HUMAN Homo sapiens 3 0.7864
Trichothecene 15-O-acetyltransferase TRI3 Q9C1B7 TRI3_FUSSP Fusarium sporotrichioides 3 0.7854
Trichothecene 15-O-acetyltransferase TRI3 Q9C1B7 TRI3_FUSSP Fusarium sporotrichioides 3 0.7854
Adenylate cyclase type 5 P30803 ADCY5_CANLF Canis lupus familiaris 4 0.7852
Adenylate cyclase type 5 P30803 ADCY5_CANLF Canis lupus familiaris 4 0.7852
Death-associated protein kinase 1 P53355 DAPK1_HUMAN Homo sapiens 3 0.7849
Death-associated protein kinase 1 P53355 DAPK1_HUMAN Homo sapiens 3 0.7849
Heat shock protein HSP 90-beta P08238 HS90B_HUMAN Homo sapiens 3 0.7813
Heat shock protein HSP 90-beta P08238 HS90B_HUMAN Homo sapiens 3 0.7813
Pteridine reductase 1 Q01782 PTR1_LEIMA Leishmania major 4 0.7810
Pteridine reductase 1 Q01782 PTR1_LEIMA Leishmania major 4 0.7810
Aminoglycoside 3'-phosphotransferase AphA1-IAB B0VD92 B0VD92_ACIBY Acinetobacter baumannii 3 0.7808
Aminoglycoside 3'-phosphotransferase AphA1-IAB B0VD92 B0VD92_ACIBY Acinetobacter baumannii 3 0.7808
ADP-ribosylation factor 1 P84077 ARF1_HUMAN Homo sapiens 2 0.7804
ADP-ribosylation factor 1 P84077 ARF1_HUMAN Homo sapiens 2 0.7804
Methylketone synthase I E0YCS2 E0YCS2_SOLHA Solanum habrochaites 2 0.7803
Methylketone synthase I E0YCS2 E0YCS2_SOLHA Solanum habrochaites 2 0.7803
Biotin carboxylase P24182 ACCC_ECOLI Escherichia coli 4 0.7799
Biotin carboxylase P24182 ACCC_ECOLI Escherichia coli 4 0.7799
Heat shock protein HSP 90-alpha P07900 HS90A_HUMAN Homo sapiens 3 0.7791
Heat shock protein HSP 90-alpha P07900 HS90A_HUMAN Homo sapiens 3 0.7791
Homoserine dehydrogenase P31116 DHOM_YEAST Saccharomyces cerevisiae 3 0.7791
Homoserine dehydrogenase P31116 DHOM_YEAST Saccharomyces cerevisiae 3 0.7791
Histidine kinase 4 Q9C5U0 AHK4_ARATH Arabidopsis thaliana 4 0.7790
Histidine kinase 4 Q9C5U0 AHK4_ARATH Arabidopsis thaliana 4 0.7790
3-ketosteroid dehydrogenase Q9RA02 Q9RA02_RHOER Rhodococcus erythropolis 3 0.7784
3-ketosteroid dehydrogenase Q9RA02 Q9RA02_RHOER Rhodococcus erythropolis 3 0.7784
Polyribonucleotide nucleotidyltransferase A7ZS61 PNP_ECO24 Escherichia coli O139:H28 3 0.7781
Polyribonucleotide nucleotidyltransferase A7ZS61 PNP_ECO24 Escherichia coli O139:H28 3 0.7781
Pteridine reductase, putative Q581W1 Q581W1_TRYB2 Trypanosoma brucei brucei 4 0.7780
Pteridine reductase, putative Q581W1 Q581W1_TRYB2 Trypanosoma brucei brucei 4 0.7780
Casein kinase II subunit alpha P68400 CSK21_HUMAN Homo sapiens 3 0.7775
11-beta-hydroxysteroid dehydrogenase 1 P50172 DHI1_MOUSE Mus musculus 3 0.7775
Casein kinase II subunit alpha P68400 CSK21_HUMAN Homo sapiens 3 0.7775
Poly [ADP-ribose] polymerase tankyrase-2 Q9H2K2 TNKS2_HUMAN Homo sapiens 3 0.7775
Poly [ADP-ribose] polymerase tankyrase-2 Q9H2K2 TNKS2_HUMAN Homo sapiens 3 0.7775
11-beta-hydroxysteroid dehydrogenase 1 P50172 DHI1_MOUSE Mus musculus 3 0.7775
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 O88703 HCN2_MOUSE Mus musculus 3 0.7774
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 O88703 HCN2_MOUSE Mus musculus 3 0.7774
Endothiapepsin P11838 CARP_CRYPA Cryphonectria parasitica 3 0.7767
Endothiapepsin P11838 CARP_CRYPA Cryphonectria parasitica 3 0.7767
Death-associated protein kinase 1 P53355 DAPK1_HUMAN Homo sapiens 3 0.7761
Death-associated protein kinase 1 P53355 DAPK1_HUMAN Homo sapiens 3 0.7761
Cytochrome P450 2C5 P00179 CP2C5_RABIT Oryctolagus cuniculus 3 0.7754
Cytochrome P450 2C5 P00179 CP2C5_RABIT Oryctolagus cuniculus 3 0.7754
Phosphodiesterase Q8WQX9 Q8WQX9_9TRYP Trypanosoma brucei 3 0.7753
Phosphodiesterase Q8WQX9 Q8WQX9_9TRYP Trypanosoma brucei 3 0.7753
Dihydrofolate reductase P0A017 DYR_STAAU Staphylococcus aureus 3 0.7751
Dihydrofolate reductase P0A017 DYR_STAAU Staphylococcus aureus 3 0.7751
HTH-type transcriptional regulator TtgR Q9AIU0 TTGR_PSEPT Pseudomonas putida 3 0.7749
HTH-type transcriptional regulator TtgR Q9AIU0 TTGR_PSEPT Pseudomonas putida 3 0.7749
Lactotransferrin P24627 TRFL_BOVIN Bos taurus 3 0.7743
Lactotransferrin P24627 TRFL_BOVIN Bos taurus 3 0.7743
Proto-oncogene tyrosine-protein kinase Src P12931 SRC_HUMAN Homo sapiens 3 0.7741
Proto-oncogene tyrosine-protein kinase Src P12931 SRC_HUMAN Homo sapiens 3 0.7741
Estrogen receptor beta Q92731 ESR2_HUMAN Homo sapiens 4 0.7735
Dipeptidyl peptidase 4 P27487 DPP4_HUMAN Homo sapiens 3 0.7735
Estrogen receptor beta Q92731 ESR2_HUMAN Homo sapiens 4 0.7735
Dipeptidyl peptidase 4 P27487 DPP4_HUMAN Homo sapiens 3 0.7735
Death-associated protein kinase 1 P53355 DAPK1_HUMAN Homo sapiens 3 0.7733
Death-associated protein kinase 1 P53355 DAPK1_HUMAN Homo sapiens 3 0.7733
11-beta-hydroxysteroid dehydrogenase 1 P28845 DHI1_HUMAN Homo sapiens 3 0.7732
11-beta-hydroxysteroid dehydrogenase 1 P28845 DHI1_HUMAN Homo sapiens 3 0.7732
Glucan 1,3-beta-glucosidase P29717 EXG1_CANAL Candida albicans 3 0.7728
Glucan 1,3-beta-glucosidase P29717 EXG1_CANAL Candida albicans 3 0.7728
3-hydroxyisobutyryl-CoA hydrolase, mitochondrial Q6NVY1 HIBCH_HUMAN Homo sapiens 3 0.7727
3-hydroxyisobutyryl-CoA hydrolase, mitochondrial Q6NVY1 HIBCH_HUMAN Homo sapiens 3 0.7727
Proliferating cell nuclear antigen P12004 PCNA_HUMAN Homo sapiens 3 0.7727
Proliferating cell nuclear antigen P12004 PCNA_HUMAN Homo sapiens 3 0.7727
Basic phospholipase A2 VRV-PL-VIIIa P59071 PA2B8_DABRR Daboia russelii 2 0.7725
Basic phospholipase A2 VRV-PL-VIIIa P59071 PA2B8_DABRR Daboia russelii 2 0.7725
Casein kinase II subunit alpha P28523 CSK2A_MAIZE Zea mays 4 0.7722
Casein kinase II subunit alpha P28523 CSK2A_MAIZE Zea mays 4 0.7722
Cytohesin-2 Q99418 CYH2_HUMAN Homo sapiens 3 0.7720
Cytohesin-2 Q99418 CYH2_HUMAN Homo sapiens 3 0.7720
Methionine adenosyltransferase 2 subunit beta Q9NZL9 MAT2B_HUMAN Homo sapiens 4 0.7719
Methionine adenosyltransferase 2 subunit beta Q9NZL9 MAT2B_HUMAN Homo sapiens 4 0.7719
Serpin domain-containing protein H0ZQY2 H0ZQY2_TAEGU Taeniopygia guttata 3 0.7718
Serpin domain-containing protein H0ZQY2 H0ZQY2_TAEGU Taeniopygia guttata 3 0.7718
Death-associated protein kinase 1 P53355 DAPK1_HUMAN Homo sapiens 3 0.7717
Death-associated protein kinase 1 P53355 DAPK1_HUMAN Homo sapiens 3 0.7717
Albumin P02768 ALBU_HUMAN Homo sapiens 3 0.7716
Albumin P02768 ALBU_HUMAN Homo sapiens 3 0.7716
Carbonic anhydrase 2 P00918 CAH2_HUMAN Homo sapiens 3 0.7714
Carbonic anhydrase 2 P00918 CAH2_HUMAN Homo sapiens 3 0.7714
Serine/threonine-protein kinase Chk1 O14757 CHK1_HUMAN Homo sapiens 3 0.7713
Serine/threonine-protein kinase Chk1 O14757 CHK1_HUMAN Homo sapiens 3 0.7713
Dihydrofolate reductase P00374 DYR_HUMAN Homo sapiens 4 0.7713
Dihydrofolate reductase P00374 DYR_HUMAN Homo sapiens 4 0.7713
Thymidylate synthase P0A884 TYSY_ECOLI Escherichia coli 4 0.7711
Thymidylate synthase P0A884 TYSY_ECOLI Escherichia coli 4 0.7711
DNA topoisomerase 4 subunit B H7C794 PARE_ENTFA Enterococcus faecalis 3 0.7709
DNA topoisomerase 4 subunit B H7C794 PARE_ENTFA Enterococcus faecalis 3 0.7709
Thymidylate synthase P0A884 TYSY_ECOLI Escherichia coli 4 0.7708
Thymidylate synthase P0A884 TYSY_ECOLI Escherichia coli 4 0.7708
Lactoperoxidase P80025 PERL_BOVIN Bos taurus 3 0.7708
Lactoperoxidase P80025 PERL_BOVIN Bos taurus 3 0.7708
Beta-secretase 1 P56817 BACE1_HUMAN Homo sapiens 3 0.7700
Beta-secretase 1 P56817 BACE1_HUMAN Homo sapiens 3 0.7700
Estrogen receptor P03372 ESR1_HUMAN Homo sapiens 3 0.7700
Estrogen receptor P03372 ESR1_HUMAN Homo sapiens 3 0.7700
Queuine tRNA-ribosyltransferase P28720 TGT_ZYMMO Zymomonas mobilis subsp. mobilis 3 0.7699
Gag-Pol polyprotein P03369 POL_HV1A2 Human immunodeficiency virus type 1 group M subtype B 3 0.7699
Queuine tRNA-ribosyltransferase P28720 TGT_ZYMMO Zymomonas mobilis subsp. mobilis 3 0.7699
Gag-Pol polyprotein P03369 POL_HV1A2 Human immunodeficiency virus type 1 group M subtype B 3 0.7699
Poly [ADP-ribose] polymerase tankyrase-2 Q9H2K2 TNKS2_HUMAN Homo sapiens 4 0.7693
Poly [ADP-ribose] polymerase tankyrase-2 Q9H2K2 TNKS2_HUMAN Homo sapiens 4 0.7693
Beta-secretase 1 P56817 BACE1_HUMAN Homo sapiens 2 0.7686
Dihydrofolate reductase P0ABQ4 DYR_ECOLI Escherichia coli 3 0.7686
Dihydrofolate reductase P0ABQ4 DYR_ECOLI Escherichia coli 3 0.7686
Beta-secretase 1 P56817 BACE1_HUMAN Homo sapiens 2 0.7686
Basic phospholipase A2 VRV-PL-VIIIa P59071 PA2B8_DABRR Daboia russelii 2 0.7684
Casein kinase II subunit alpha P28523 CSK2A_MAIZE Zea mays 3 0.7684
Basic phospholipase A2 VRV-PL-VIIIa P59071 PA2B8_DABRR Daboia russelii 2 0.7684
Casein kinase II subunit alpha P28523 CSK2A_MAIZE Zea mays 3 0.7684
cAMP-dependent protein kinase type I-alpha regulatory subunit P00514 KAP0_BOVIN Bos taurus 3 0.7683
cAMP-dependent protein kinase type I-alpha regulatory subunit P00514 KAP0_BOVIN Bos taurus 3 0.7683
Adenylate cyclase type 5 P30803 ADCY5_CANLF Canis lupus familiaris 4 0.7679
Adenylate cyclase type 5 P30803 ADCY5_CANLF Canis lupus familiaris 4 0.7679
Acetylcholinesterase P22303 ACES_HUMAN Homo sapiens 3 0.7676
Acetylcholinesterase P22303 ACES_HUMAN Homo sapiens 3 0.7676
DNA-binding transcriptional dual regulator CRP P0ACJ8 CRP_ECOLI Escherichia coli 3 0.7672
DNA-binding transcriptional dual regulator CRP P0ACJ8 CRP_ECOLI Escherichia coli 3 0.7672
FMN-dependent NAD(P)H:quinone oxidoreductase 1 Q9I5F3 AZOR1_PSEAE Pseudomonas aeruginosa 3 0.7668
FMN-dependent NAD(P)H:quinone oxidoreductase 1 Q9I5F3 AZOR1_PSEAE Pseudomonas aeruginosa 3 0.7668
Putative pteridine reductase 2 Q8I814 Q8I814_TRYCR Trypanosoma cruzi 4 0.7666
Putative pteridine reductase 2 Q8I814 Q8I814_TRYCR Trypanosoma cruzi 4 0.7666
Calmodulin-like domain protein kinase isoenzyme gamma, related F0V9W9 F0V9W9_NEOCL Neospora caninum 3 0.7661
Calmodulin-like domain protein kinase isoenzyme gamma, related F0V9W9 F0V9W9_NEOCL Neospora caninum 3 0.7661
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 Q9Y3Q4 HCN4_HUMAN Homo sapiens 3 0.7659
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 Q9Y3Q4 HCN4_HUMAN Homo sapiens 3 0.7659
Proto-oncogene tyrosine-protein kinase Src P12931 SRC_HUMAN Homo sapiens 3 0.7658
Proto-oncogene tyrosine-protein kinase Src P12931 SRC_HUMAN Homo sapiens 3 0.7658
Major pollen allergen Bet v 1-A P15494 BEV1A_BETPN Betula pendula 3 0.7656
Major pollen allergen Bet v 1-A P15494 BEV1A_BETPN Betula pendula 3 0.7656
Secoisolariciresinol dehydrogenase Q94KL8 SILD_PODPE Podophyllum peltatum 3 0.7654
Secoisolariciresinol dehydrogenase Q94KL8 SILD_PODPE Podophyllum peltatum 3 0.7654
Serine/threonine-protein kinase pim-1 P11309 PIM1_HUMAN Homo sapiens 3 0.7652
Serine/threonine-protein kinase pim-1 P11309 PIM1_HUMAN Homo sapiens 3 0.7652
Matrix metalloproteinase-9 P14780 MMP9_HUMAN Homo sapiens 3 0.7650
Glucose-1-phosphate thymidylyltransferase Q9HU22 Q9HU22_PSEAE Pseudomonas aeruginosa 3 0.7650
Matrix metalloproteinase-9 P14780 MMP9_HUMAN Homo sapiens 3 0.7650
Glucose-1-phosphate thymidylyltransferase Q9HU22 Q9HU22_PSEAE Pseudomonas aeruginosa 3 0.7650
orotidine-5'-phosphate decarboxylase Q8T6J6 Q8T6J6_PLAFA Plasmodium falciparum 4 0.7647
orotidine-5'-phosphate decarboxylase Q8T6J6 Q8T6J6_PLAFA Plasmodium falciparum 4 0.7647
Nitric oxide synthase 1 P29476 NOS1_RAT Rattus norvegicus 4 0.7647
Nitric oxide synthase 1 P29476 NOS1_RAT Rattus norvegicus 4 0.7647
cGMP-specific 3',5'-cyclic phosphodiesterase O76074 PDE5A_HUMAN Homo sapiens 3 0.7646
cGMP-specific 3',5'-cyclic phosphodiesterase O76074 PDE5A_HUMAN Homo sapiens 3 0.7646
Poly [ADP-ribose] polymerase tankyrase-2 Q9H2K2 TNKS2_HUMAN Homo sapiens 4 0.7645
Poly [ADP-ribose] polymerase tankyrase-2 Q9H2K2 TNKS2_HUMAN Homo sapiens 4 0.7645
Catechol O-methyltransferase P22734 COMT_RAT Rattus norvegicus 3 0.7641
Catechol O-methyltransferase P22734 COMT_RAT Rattus norvegicus 3 0.7641
Thymidylate synthase P00469 TYSY_LACCA Lacticaseibacillus casei 2 0.7637
Thymidylate synthase P00469 TYSY_LACCA Lacticaseibacillus casei 2 0.7637
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial Q15119 PDK2_HUMAN Homo sapiens 3 0.7632
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial Q15119 PDK2_HUMAN Homo sapiens 3 0.7632
Adenylate cyclase type 5 P30803 ADCY5_CANLF Canis lupus familiaris 3 0.7629
Adenylate cyclase type 5 P30803 ADCY5_CANLF Canis lupus familiaris 3 0.7629
Beta-secretase 1 P56817 BACE1_HUMAN Homo sapiens 3 0.7622
Beta-secretase 1 P56817 BACE1_HUMAN Homo sapiens 3 0.7622
C-1-tetrahydrofolate synthase, cytoplasmic P11586 C1TC_HUMAN Homo sapiens 3 0.7619
C-1-tetrahydrofolate synthase, cytoplasmic P11586 C1TC_HUMAN Homo sapiens 3 0.7619
Lactoperoxidase A0A452E9Y6 PERL_CAPHI Capra hircus 3 0.7615
Lactoperoxidase A0A452E9Y6 PERL_CAPHI Capra hircus 3 0.7615
Serine/threonine-protein kinase Chk1 O14757 CHK1_HUMAN Homo sapiens 3 0.7611
Serine/threonine-protein kinase Chk1 O14757 CHK1_HUMAN Homo sapiens 3 0.7611
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 Q9Y3Q4 HCN4_HUMAN Homo sapiens 3 0.7610
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 Q9Y3Q4 HCN4_HUMAN Homo sapiens 3 0.7610
Chalcone--flavanone isomerase 1 P28012 CFI1_MEDSA Medicago sativa 4 0.7608
Chalcone--flavanone isomerase 1 P28012 CFI1_MEDSA Medicago sativa 4 0.7608
L-lactate dehydrogenase A chain P13491 LDHA_RABIT Oryctolagus cuniculus 2 0.7604
L-lactate dehydrogenase A chain P13491 LDHA_RABIT Oryctolagus cuniculus 2 0.7604
Acetolactate synthase, chloroplastic P17597 ILVB_ARATH Arabidopsis thaliana 2 0.7600
Acetolactate synthase, chloroplastic P17597 ILVB_ARATH Arabidopsis thaliana 2 0.7600
Nitric oxide synthase, inducible P29477 NOS2_MOUSE Mus musculus 4 0.7599
Nitric oxide synthase, inducible P29477 NOS2_MOUSE Mus musculus 4 0.7599
Serine/threonine-protein kinase pim-1 P11309 PIM1_HUMAN Homo sapiens 3 0.7596
Serine/threonine-protein kinase pim-1 P11309 PIM1_HUMAN Homo sapiens 3 0.7596
Flavin-dependent thymidylate synthase Q9WYT0 THYX_THEMA Thermotoga maritima 3 0.7595
Flavin-dependent thymidylate synthase Q9WYT0 THYX_THEMA Thermotoga maritima 3 0.7595
Cyclin-dependent kinase 2 P24941 CDK2_HUMAN Homo sapiens 3 0.7594
Cyclin-dependent kinase 2 P24941 CDK2_HUMAN Homo sapiens 3 0.7594
Angiopoietin-1 receptor Q02763 TIE2_HUMAN Homo sapiens 3 0.7591
Angiopoietin-1 receptor Q02763 TIE2_HUMAN Homo sapiens 3 0.7591
Glucan 1,3-beta-glucosidase P29717 EXG1_CANAL Candida albicans 3 0.7590
Glucan 1,3-beta-glucosidase P29717 EXG1_CANAL Candida albicans 3 0.7590
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial Q15119 PDK2_HUMAN Homo sapiens 3 0.7590
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial Q15119 PDK2_HUMAN Homo sapiens 3 0.7590
Lactoylglutathione lyase Q9CPU0 LGUL_MOUSE Mus musculus 2 0.7588
Lactoylglutathione lyase Q9CPU0 LGUL_MOUSE Mus musculus 2 0.7588
Ephrin type-B receptor 4 P54760 EPHB4_HUMAN Homo sapiens 3 0.7583
Cytokinin dehydrogenase 1 Q9T0N8 CKX1_MAIZE Zea mays 3 0.7583
Cytokinin dehydrogenase 1 Q9T0N8 CKX1_MAIZE Zea mays 3 0.7583
Ephrin type-B receptor 4 P54760 EPHB4_HUMAN Homo sapiens 3 0.7583
Aldehyde dehydrogenase, dimeric NADP-preferring P30838 AL3A1_HUMAN Homo sapiens 3 0.7577
C-1-tetrahydrofolate synthase, cytoplasmic P11586 C1TC_HUMAN Homo sapiens 4 0.7577
C-1-tetrahydrofolate synthase, cytoplasmic P11586 C1TC_HUMAN Homo sapiens 4 0.7577
Aldehyde dehydrogenase, dimeric NADP-preferring P30838 AL3A1_HUMAN Homo sapiens 3 0.7577
Serine/threonine-protein kinase Chk1 O14757 CHK1_HUMAN Homo sapiens 3 0.7574
Serine/threonine-protein kinase Chk1 O14757 CHK1_HUMAN Homo sapiens 3 0.7574
Tyrosine-protein kinase Lck P06239 LCK_HUMAN Homo sapiens 3 0.7573
Tyrosine-protein kinase Lck P06239 LCK_HUMAN Homo sapiens 3 0.7573
Thermolysin P00800 THER_BACTH Bacillus thermoproteolyticus 3 0.7571
Thermolysin P00800 THER_BACTH Bacillus thermoproteolyticus 3 0.7571
Nitric oxide synthase, inducible P29477 NOS2_MOUSE Mus musculus 3 0.7568
Dihydrofolate reductase P00374 DYR_HUMAN Homo sapiens 3 0.7568
Dihydrofolate reductase P00374 DYR_HUMAN Homo sapiens 3 0.7568
Nitric oxide synthase, inducible P29477 NOS2_MOUSE Mus musculus 3 0.7568
Heat shock protein 75 kDa, mitochondrial Q12931 TRAP1_HUMAN Homo sapiens 3 0.7565
Heat shock protein 75 kDa, mitochondrial Q12931 TRAP1_HUMAN Homo sapiens 3 0.7565
Poly [ADP-ribose] polymerase tankyrase-2 Q9H2K2 TNKS2_HUMAN Homo sapiens 4 0.7564
Ribosomal protein S6 kinase alpha-3 P18654 KS6A3_MOUSE Mus musculus 5 0.7564
Poly [ADP-ribose] polymerase tankyrase-2 Q9H2K2 TNKS2_HUMAN Homo sapiens 4 0.7564
Ribosomal protein S6 kinase alpha-3 P18654 KS6A3_MOUSE Mus musculus 5 0.7564
Beta-secretase 1 P56817 BACE1_HUMAN Homo sapiens 3 0.7557
Beta-secretase 1 P56817 BACE1_HUMAN Homo sapiens 3 0.7557
Thymidylate synthase P00469 TYSY_LACCA Lacticaseibacillus casei 3 0.7553
Thymidylate synthase P00469 TYSY_LACCA Lacticaseibacillus casei 3 0.7553
Prothrombin P00734 THRB_HUMAN Homo sapiens 3 0.7551
Prothrombin P00734 THRB_HUMAN Homo sapiens 3 0.7551
Phenylalanine-4-hydroxylase P00439 PH4H_HUMAN Homo sapiens 3 0.7549
Phenylalanine-4-hydroxylase P00439 PH4H_HUMAN Homo sapiens 3 0.7549
Serine/threonine-protein kinase Chk1 O14757 CHK1_HUMAN Homo sapiens 3 0.7549
Serine/threonine-protein kinase Chk1 O14757 CHK1_HUMAN Homo sapiens 3 0.7549
Poly [ADP-ribose] polymerase tankyrase-2 Q9H2K2 TNKS2_HUMAN Homo sapiens 4 0.7548
Poly [ADP-ribose] polymerase tankyrase-2 Q9H2K2 TNKS2_HUMAN Homo sapiens 4 0.7548
Nuclear receptor subfamily 1 group I member 3 O35627 NR1I3_MOUSE Mus musculus 2 0.7546
Nuclear receptor subfamily 1 group I member 3 O35627 NR1I3_MOUSE Mus musculus 2 0.7546
Odorant binding protein ASP1 Q8WRW5 Q8WRW5_APIME Apis mellifera 3 0.7545
Odorant binding protein ASP1 Q8WRW5 Q8WRW5_APIME Apis mellifera 3 0.7545
Phosphoribosylformylglycinamidine synthase subunit PurL Q9X0X3 PURL_THEMA Thermotoga maritima 3 0.7543
Phosphoribosylformylglycinamidine synthase subunit PurL Q9X0X3 PURL_THEMA Thermotoga maritima 3 0.7543
Thymidylate synthase ThyA P9WFR9 TYSY_MYCTU Mycobacterium tuberculosis 3 0.7541
Thymidylate synthase ThyA P9WFR9 TYSY_MYCTU Mycobacterium tuberculosis 3 0.7541
Multidrug efflux pump subunit AcrB P31224 ACRB_ECOLI Escherichia coli 3 0.7539
Multidrug efflux pump subunit AcrB P31224 ACRB_ECOLI Escherichia coli 3 0.7539
GCN5-related N-acetyltransferase B1YEL6 B1YEL6_EXIS2 Exiguobacterium sibiricum 3 0.7538
GCN5-related N-acetyltransferase B1YEL6 B1YEL6_EXIS2 Exiguobacterium sibiricum 3 0.7538
cGMP-dependent protein kinase, putative A5K0N4 A5K0N4_PLAVS Plasmodium vivax 3 0.7537
cGMP-dependent protein kinase, putative A5K0N4 A5K0N4_PLAVS Plasmodium vivax 3 0.7537
HTH-type transcriptional regulator EthR P9WMC1 ETHR_MYCTU Mycobacterium tuberculosis 3 0.7536
HTH-type transcriptional regulator EthR P9WMC1 ETHR_MYCTU Mycobacterium tuberculosis 3 0.7536
Nitric oxide synthase, inducible P29477 NOS2_MOUSE Mus musculus 3 0.7528
Nitric oxide synthase, inducible P29477 NOS2_MOUSE Mus musculus 3 0.7528
Thymidine phosphorylase Q7CP66 TYPH_SALTY Salmonella typhimurium 3 0.7527
Thymidine phosphorylase Q7CP66 TYPH_SALTY Salmonella typhimurium 3 0.7527
Poly [ADP-ribose] polymerase tankyrase-2 Q9H2K2 TNKS2_HUMAN Homo sapiens 4 0.7525
Poly [ADP-ribose] polymerase tankyrase-2 Q9H2K2 TNKS2_HUMAN Homo sapiens 4 0.7525
Hypoxanthine phosphoribosyltransferase Q4DRC4 Q4DRC4_TRYCC Trypanosoma cruzi 3 0.7520
Hypoxanthine phosphoribosyltransferase Q4DRC4 Q4DRC4_TRYCC Trypanosoma cruzi 3 0.7520
Vitamin D3 dihydroxylase P18326 CPXE_STRGO Streptomyces griseolus 3 0.7519
Vitamin D3 dihydroxylase P18326 CPXE_STRGO Streptomyces griseolus 3 0.7519
Transthyretin P02766 TTHY_HUMAN Homo sapiens 3 0.7516
Transthyretin P02766 TTHY_HUMAN Homo sapiens 3 0.7516
Bromodomain-containing protein 2 P25440 BRD2_HUMAN Homo sapiens 3 0.7516
Bromodomain-containing protein 2 P25440 BRD2_HUMAN Homo sapiens 3 0.7516
Beta-secretase 1 P56817 BACE1_HUMAN Homo sapiens 3 0.7514
Soluble acetylcholine receptor Q8WSF8 Q8WSF8_APLCA Aplysia californica 2 0.7514
Vascular endothelial growth factor receptor 2 P35968 VGFR2_HUMAN Homo sapiens 3 0.7514
Vascular endothelial growth factor receptor 2 P35968 VGFR2_HUMAN Homo sapiens 3 0.7514
Beta-secretase 1 P56817 BACE1_HUMAN Homo sapiens 3 0.7514
Soluble acetylcholine receptor Q8WSF8 Q8WSF8_APLCA Aplysia californica 2 0.7514
GCN5-related N-acetyltransferase B1YEL6 B1YEL6_EXIS2 Exiguobacterium sibiricum 3 0.7511
GCN5-related N-acetyltransferase B1YEL6 B1YEL6_EXIS2 Exiguobacterium sibiricum 3 0.7511
Acetylcholinesterase P21836 ACES_MOUSE Mus musculus 2 0.7507
Acetylcholinesterase P21836 ACES_MOUSE Mus musculus 2 0.7507
Nitric oxide synthase, inducible P29477 NOS2_MOUSE Mus musculus 3 0.7504
Nitric oxide synthase, inducible P29477 NOS2_MOUSE Mus musculus 3 0.7504
Histone deacetylase 8 Q9BY41 HDAC8_HUMAN Homo sapiens 2 0.7500
Histone deacetylase 8 Q9BY41 HDAC8_HUMAN Homo sapiens 2 0.7500
Nitric oxide synthase, inducible P29477 NOS2_MOUSE Mus musculus 3 0.7498
Nitric oxide synthase, inducible P29477 NOS2_MOUSE Mus musculus 3 0.7498
Fibroblast growth factor receptor 1 P11362 FGFR1_HUMAN Homo sapiens 3 0.7496
Fibroblast growth factor receptor 1 P11362 FGFR1_HUMAN Homo sapiens 3 0.7496
Vitamin D3 dihydroxylase P18326 CPXE_STRGO Streptomyces griseolus 3 0.7492
Vitamin D3 dihydroxylase P18326 CPXE_STRGO Streptomyces griseolus 3 0.7492
ActVA 6 protein Q53908 Q53908_STRCH Streptomyces coelicolor 3 0.7491
ActVA 6 protein Q53908 Q53908_STRCH Streptomyces coelicolor 3 0.7491
tyrosine--tRNA ligase Q4QFJ7 Q4QFJ7_LEIMA Leishmania major 3 0.7489
tyrosine--tRNA ligase Q4QFJ7 Q4QFJ7_LEIMA Leishmania major 3 0.7489
Beta-1 adrenergic receptor P07700 ADRB1_MELGA Meleagris gallopavo 2 0.7488
Beta-1 adrenergic receptor P07700 ADRB1_MELGA Meleagris gallopavo 2 0.7488
Nitric oxide synthase, inducible P29477 NOS2_MOUSE Mus musculus 3 0.7486
Nitric oxide synthase, inducible P29477 NOS2_MOUSE Mus musculus 3 0.7486
Seminal ribonuclease P00669 RNS_BOVIN Bos taurus 3 0.7485
Seminal ribonuclease P00669 RNS_BOVIN Bos taurus 3 0.7485
Dipeptidyl peptidase 4 P22411 DPP4_PIG Sus scrofa 3 0.7482
Dipeptidyl peptidase 4 P22411 DPP4_PIG Sus scrofa 3 0.7482
Albumin P02768 ALBU_HUMAN Homo sapiens 3 0.7477
Albumin P02768 ALBU_HUMAN Homo sapiens 3 0.7477
Queuine tRNA-ribosyltransferase P28720 TGT_ZYMMO Zymomonas mobilis subsp. mobilis 3 0.7471
Queuine tRNA-ribosyltransferase P28720 TGT_ZYMMO Zymomonas mobilis subsp. mobilis 3 0.7471
Beta-secretase 1 P56817 BACE1_HUMAN Homo sapiens 3 0.7470
Beta-secretase 1 P56817 BACE1_HUMAN Homo sapiens 3 0.7470
Antiviral protein I P10297 RIP1_PHYAM Phytolacca americana 4 0.7468
Antiviral protein I P10297 RIP1_PHYAM Phytolacca americana 4 0.7468
Heat shock protein HSP 90-alpha P07900 HS90A_HUMAN Homo sapiens 3 0.7467
Heat shock protein HSP 90-alpha P07900 HS90A_HUMAN Homo sapiens 3 0.7467
Bifunctional epoxide hydrolase 2 P34913 HYES_HUMAN Homo sapiens 2 0.7465
Bifunctional epoxide hydrolase 2 P34913 HYES_HUMAN Homo sapiens 2 0.7465
Dihydrofolate reductase P00374 DYR_HUMAN Homo sapiens 4 0.7464
Dihydrofolate reductase P00374 DYR_HUMAN Homo sapiens 4 0.7464
Poly [ADP-ribose] polymerase tankyrase-2 Q9H2K2 TNKS2_HUMAN Homo sapiens 4 0.7463
Nitric oxide synthase, inducible P29477 NOS2_MOUSE Mus musculus 4 0.7463
Poly [ADP-ribose] polymerase tankyrase-2 Q9H2K2 TNKS2_HUMAN Homo sapiens 4 0.7463
Nitric oxide synthase, inducible P29477 NOS2_MOUSE Mus musculus 4 0.7463
Casein kinase II subunit alpha P68400 CSK21_HUMAN Homo sapiens 3 0.7460
Casein kinase II subunit alpha P68400 CSK21_HUMAN Homo sapiens 3 0.7460
Gag-Pol polyprotein P03369 POL_HV1A2 Human immunodeficiency virus type 1 group M subtype B 3 0.7459
Gag-Pol polyprotein P03369 POL_HV1A2 Human immunodeficiency virus type 1 group M subtype B 3 0.7459
Ribosyldihydronicotinamide dehydrogenase [quinone] P16083 NQO2_HUMAN Homo sapiens 3 0.7458
Ribosyldihydronicotinamide dehydrogenase [quinone] P16083 NQO2_HUMAN Homo sapiens 3 0.7458
ATP-dependent molecular chaperone HSP82 P02829 HSP82_YEAST Saccharomyces cerevisiae 3 0.7456
ATP-dependent molecular chaperone HSP82 P02829 HSP82_YEAST Saccharomyces cerevisiae 3 0.7456
Bifunctional dihydrofolate reductase-thymidylate synthase Q27793 DRTS_TRYCR Trypanosoma cruzi 3 0.7454
Bifunctional dihydrofolate reductase-thymidylate synthase Q27793 DRTS_TRYCR Trypanosoma cruzi 3 0.7454
Genome polyprotein O92972 POLG_HCVJ4 Hepatitis C virus genotype 1b 3 0.7448
Genome polyprotein O92972 POLG_HCVJ4 Hepatitis C virus genotype 1b 3 0.7448
Basic phospholipase A2 VRV-PL-VIIIa P59071 PA2B8_DABRR Daboia russelii 3 0.7447
Basic phospholipase A2 VRV-PL-VIIIa P59071 PA2B8_DABRR Daboia russelii 3 0.7447
Poly [ADP-ribose] polymerase tankyrase-2 Q9H2K2 TNKS2_HUMAN Homo sapiens 4 0.7443
Poly [ADP-ribose] polymerase tankyrase-2 Q9H2K2 TNKS2_HUMAN Homo sapiens 4 0.7443
Cyclin-dependent kinase 2 P24941 CDK2_HUMAN Homo sapiens 3 0.7441
Cyclin-dependent kinase 2 P24941 CDK2_HUMAN Homo sapiens 3 0.7441
Poly [ADP-ribose] polymerase tankyrase-2 Q9H2K2 TNKS2_HUMAN Homo sapiens 4 0.7441
Poly [ADP-ribose] polymerase tankyrase-2 Q9H2K2 TNKS2_HUMAN Homo sapiens 4 0.7441
Methionine aminopeptidase 2 P9WK19 MAP12_MYCTU Mycobacterium tuberculosis 3 0.7433
Methionine aminopeptidase 2 P9WK19 MAP12_MYCTU Mycobacterium tuberculosis 3 0.7433
Beta-secretase 1 P56817 BACE1_HUMAN Homo sapiens 3 0.7430
Beta-secretase 1 P56817 BACE1_HUMAN Homo sapiens 3 0.7430
Alpha-1-acid glycoprotein 2 P19652 A1AG2_HUMAN Homo sapiens 3 0.7428
Alpha-1-acid glycoprotein 2 P19652 A1AG2_HUMAN Homo sapiens 3 0.7428
Serine/threonine-protein kinase PLK1 P53350 PLK1_HUMAN Homo sapiens 3 0.7426
Serine/threonine-protein kinase PLK1 P53350 PLK1_HUMAN Homo sapiens 3 0.7426
Nitric oxide synthase, inducible P29477 NOS2_MOUSE Mus musculus 3 0.7426
Nitric oxide synthase, inducible P29477 NOS2_MOUSE Mus musculus 3 0.7426
Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial P08559 ODPA_HUMAN Homo sapiens 3 0.7422
Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial P08559 ODPA_HUMAN Homo sapiens 3 0.7422
Aldehyde dehydrogenase, mitochondrial P05091 ALDH2_HUMAN Homo sapiens 3 0.7421
Aldehyde dehydrogenase, mitochondrial P05091 ALDH2_HUMAN Homo sapiens 3 0.7421
Putative cytochrome P450 Q70AS3 Q70AS3_STRPE Streptomyces peucetius 3 0.7416
Putative cytochrome P450 Q70AS3 Q70AS3_STRPE Streptomyces peucetius 3 0.7416
Beta-secretase 1 P56817 BACE1_HUMAN Homo sapiens 2 0.7415
Beta-secretase 1 P56817 BACE1_HUMAN Homo sapiens 2 0.7415
Glutamate receptor 3 P19492 GRIA3_RAT Rattus norvegicus 3 0.7411
Glutamate receptor 3 P19492 GRIA3_RAT Rattus norvegicus 3 0.7411
Cyclin-dependent kinase 6 Q00534 CDK6_HUMAN Homo sapiens 4 0.7410
Cyclin-dependent kinase 6 Q00534 CDK6_HUMAN Homo sapiens 4 0.7410
Heat shock protein HSP 90-alpha P07900 HS90A_HUMAN Homo sapiens 3 0.7409
Heat shock protein HSP 90-alpha P07900 HS90A_HUMAN Homo sapiens 3 0.7409
Lethal(3)malignant brain tumor-like protein 1 Q9Y468 LMBL1_HUMAN Homo sapiens 3 0.7407
Lethal(3)malignant brain tumor-like protein 1 Q9Y468 LMBL1_HUMAN Homo sapiens 3 0.7407
Chloramphenicol 3-O phosphotransferase Q56148 CPT_STRVP Streptomyces venezuelae 3 0.7404
Chloramphenicol 3-O phosphotransferase Q56148 CPT_STRVP Streptomyces venezuelae 3 0.7404
Poly [ADP-ribose] polymerase tankyrase-2 Q9H2K2 TNKS2_HUMAN Homo sapiens 4 0.7401
Poly [ADP-ribose] polymerase tankyrase-2 Q9H2K2 TNKS2_HUMAN Homo sapiens 4 0.7401
Gag-Pol polyprotein P04584 POL_HV2RO Human immunodeficiency virus type 2 subtype A 3 0.7397
Gag-Pol polyprotein P04584 POL_HV2RO Human immunodeficiency virus type 2 subtype A 3 0.7397
Glycogen synthase kinase-3 beta P49841 GSK3B_HUMAN Homo sapiens 2 0.7392
Glycogen synthase kinase-3 beta P49841 GSK3B_HUMAN Homo sapiens 2 0.7392
Dual specificity mitogen-activated protein kinase kinase 1 Q02750 MP2K1_HUMAN Homo sapiens 3 0.7390
Glutathione S-transferase F2 P46422 GSTF2_ARATH Arabidopsis thaliana 3 0.7390
Glutathione S-transferase F2 P46422 GSTF2_ARATH Arabidopsis thaliana 3 0.7390
Dual specificity mitogen-activated protein kinase kinase 1 Q02750 MP2K1_HUMAN Homo sapiens 3 0.7390
Nitric oxide synthase, inducible P29477 NOS2_MOUSE Mus musculus 3 0.7385
Nitric oxide synthase, inducible P29477 NOS2_MOUSE Mus musculus 3 0.7385
CREB-binding protein Q92793 CBP_HUMAN Homo sapiens 3 0.7384
CREB-binding protein Q92793 CBP_HUMAN Homo sapiens 3 0.7384
Tyrosine-protein kinase SYK P43405 KSYK_HUMAN Homo sapiens 4 0.7376
Tyrosine-protein kinase SYK P43405 KSYK_HUMAN Homo sapiens 4 0.7376
Poly [ADP-ribose] polymerase tankyrase-2 Q9H2K2 TNKS2_HUMAN Homo sapiens 4 0.7373
Poly [ADP-ribose] polymerase tankyrase-2 Q9H2K2 TNKS2_HUMAN Homo sapiens 4 0.7373
DNA ligase P43813 DNLJ_HAEIN Haemophilus influenzae 2 0.7372
DNA ligase P43813 DNLJ_HAEIN Haemophilus influenzae 2 0.7372
Oxygen-insensitive NAD(P)H nitroreductase P38489 NFSB_ECOLI Escherichia coli 3 0.7368
Oxygen-insensitive NAD(P)H nitroreductase P38489 NFSB_ECOLI Escherichia coli 3 0.7368
cAMP-dependent protein kinase type I-alpha regulatory subunit P00514 KAP0_BOVIN Bos taurus 3 0.7364
cAMP-dependent protein kinase type I-alpha regulatory subunit P00514 KAP0_BOVIN Bos taurus 3 0.7364
Purine nucleoside phosphorylase P00491 PNPH_HUMAN Homo sapiens 3 0.7357
Purine nucleoside phosphorylase P00491 PNPH_HUMAN Homo sapiens 3 0.7357
HTH-type transcriptional regulator QacR P0A0N4 QACR_STAAU Staphylococcus aureus 2 0.7357
HTH-type transcriptional regulator QacR P0A0N4 QACR_STAAU Staphylococcus aureus 2 0.7357
Nitric oxide synthase, inducible P29477 NOS2_MOUSE Mus musculus 4 0.7354
Nitric oxide synthase, inducible P29477 NOS2_MOUSE Mus musculus 4 0.7354
Acyl-homoserine-lactone synthase Q4VSJ8 Q4VSJ8_BURGL Burkholderia glumae 4 0.7353
Acyl-homoserine-lactone synthase Q4VSJ8 Q4VSJ8_BURGL Burkholderia glumae 4 0.7353
Ribosyldihydronicotinamide dehydrogenase [quinone] P16083 NQO2_HUMAN Homo sapiens 3 0.7352
Ribosyldihydronicotinamide dehydrogenase [quinone] P16083 NQO2_HUMAN Homo sapiens 3 0.7352
Endoplasmic reticulum aminopeptidase 2 Q6P179 ERAP2_HUMAN Homo sapiens 2 0.7351
Endoplasmic reticulum aminopeptidase 2 Q6P179 ERAP2_HUMAN Homo sapiens 2 0.7351
5-methylthioadenosine/S-adenosylhomocysteine deaminase Q7NZ90 Q7NZ90_CHRVO Chromobacterium violaceum 3 0.7350
3',5'-cyclic-AMP phosphodiesterase 4D Q08499 PDE4D_HUMAN Homo sapiens 3 0.7350
5-methylthioadenosine/S-adenosylhomocysteine deaminase Q7NZ90 Q7NZ90_CHRVO Chromobacterium violaceum 3 0.7350
3',5'-cyclic-AMP phosphodiesterase 4D Q08499 PDE4D_HUMAN Homo sapiens 3 0.7350
Poly [ADP-ribose] polymerase 1 P09874 PARP1_HUMAN Homo sapiens 3 0.7349
Poly [ADP-ribose] polymerase 1 P09874 PARP1_HUMAN Homo sapiens 3 0.7349
Nitric oxide synthase 1 P29476 NOS1_RAT Rattus norvegicus 3 0.7345
Nitric oxide synthase 1 P29476 NOS1_RAT Rattus norvegicus 3 0.7345
Cellular tumor antigen p53 P04637 P53_HUMAN Homo sapiens 3 0.7344
Sulfotransferase 1A1 P50225 ST1A1_HUMAN Homo sapiens 2 0.7344
Cyclin-dependent kinase 2 P24941 CDK2_HUMAN Homo sapiens 3 0.7344
Cellular tumor antigen p53 P04637 P53_HUMAN Homo sapiens 3 0.7344
Sulfotransferase 1A1 P50225 ST1A1_HUMAN Homo sapiens 2 0.7344
Cyclin-dependent kinase 2 P24941 CDK2_HUMAN Homo sapiens 3 0.7344
Heat shock protein HSP 90-alpha P07900 HS90A_HUMAN Homo sapiens 3 0.7336
Heat shock protein HSP 90-alpha P07900 HS90A_HUMAN Homo sapiens 3 0.7336
NAD(P) transhydrogenase subunit alpha part 1 Q2RSB2 PNTAA_RHORT Rhodospirillum rubrum 3 0.7335
NAD(P) transhydrogenase subunit alpha part 1 Q2RSB2 PNTAA_RHORT Rhodospirillum rubrum 3 0.7335
Cyclin-dependent kinase 2 P24941 CDK2_HUMAN Homo sapiens 3 0.7335
Cyclin-dependent kinase 2 P24941 CDK2_HUMAN Homo sapiens 3 0.7335
EbrA repressor Q79SH7 Q79SH7_STRLI Streptomyces lividans 3 0.7334
EbrA repressor Q79SH7 Q79SH7_STRLI Streptomyces lividans 3 0.7334
Beta-secretase 1 P56817 BACE1_HUMAN Homo sapiens 3 0.7333
Beta-secretase 1 P56817 BACE1_HUMAN Homo sapiens 3 0.7333
Carbonic anhydrase 4 P22748 CAH4_HUMAN Homo sapiens 3 0.7327
Carbonic anhydrase 4 P22748 CAH4_HUMAN Homo sapiens 3 0.7327
histone deacetylase A5H660 A5H660_SCHMA Schistosoma mansoni 3 0.7325
histone deacetylase A5H660 A5H660_SCHMA Schistosoma mansoni 3 0.7325
Vitamin D3 receptor A Q9PTN2 VDRA_DANRE Danio rerio 4 0.7323
Ferrochelatase, mitochondrial P22830 HEMH_HUMAN Homo sapiens 3 0.7323
Ferrochelatase, mitochondrial P22830 HEMH_HUMAN Homo sapiens 3 0.7323
Vitamin D3 receptor A Q9PTN2 VDRA_DANRE Danio rerio 4 0.7323
Peroxisome proliferator-activated receptor gamma P37231 PPARG_HUMAN Homo sapiens 2 0.7321
Kinesin-like protein KIF11 P52732 KIF11_HUMAN Homo sapiens 3 0.7321
Peroxisome proliferator-activated receptor gamma P37231 PPARG_HUMAN Homo sapiens 2 0.7321
Kinesin-like protein KIF11 P52732 KIF11_HUMAN Homo sapiens 3 0.7321
Caffeoyl-CoA O-methyltransferase Q40313 CAMT_MEDSA Medicago sativa 3 0.7320
Caffeoyl-CoA O-methyltransferase Q40313 CAMT_MEDSA Medicago sativa 3 0.7320
Transcriptional regulator, PadR-like family A2RI36 A2RI36_LACLM Lactococcus lactis subsp. cremoris 2 0.7318
Transcriptional regulator, PadR-like family A2RI36 A2RI36_LACLM Lactococcus lactis subsp. cremoris 2 0.7318
Serine/threonine-protein kinase pim-1 P11309 PIM1_HUMAN Homo sapiens 3 0.7315
Serine/threonine-protein kinase pim-1 P11309 PIM1_HUMAN Homo sapiens 3 0.7315
Gag-Pol polyprotein P12497 POL_HV1N5 Human immunodeficiency virus type 1 group M subtype B 2 0.7312
Gag-Pol polyprotein P12497 POL_HV1N5 Human immunodeficiency virus type 1 group M subtype B 2 0.7312
Gag-Pol polyprotein P12497 POL_HV1N5 Human immunodeficiency virus type 1 group M subtype B 3 0.7307
Catechol O-methyltransferase P22734 COMT_RAT Rattus norvegicus 3 0.7307
Multidrug efflux pump subunit AcrB P31224 ACRB_ECOLI Escherichia coli 3 0.7307
Catechol O-methyltransferase P22734 COMT_RAT Rattus norvegicus 3 0.7307
Multidrug efflux pump subunit AcrB P31224 ACRB_ECOLI Escherichia coli 3 0.7307
Gag-Pol polyprotein P12497 POL_HV1N5 Human immunodeficiency virus type 1 group M subtype B 3 0.7307
Aldehyde dehydrogenase, mitochondrial P05091 ALDH2_HUMAN Homo sapiens 3 0.7303
Aldehyde dehydrogenase, mitochondrial P05091 ALDH2_HUMAN Homo sapiens 3 0.7303
Carbonic anhydrase 2 P00918 CAH2_HUMAN Homo sapiens 2 0.7302
Carbonic anhydrase 2 P00918 CAH2_HUMAN Homo sapiens 2 0.7302
Tyrosine-protein kinase JAK2 O60674 JAK2_HUMAN Homo sapiens 3 0.7300
Tyrosine-protein kinase JAK2 O60674 JAK2_HUMAN Homo sapiens 3 0.7300
Beta-secretase 1 P56817 BACE1_HUMAN Homo sapiens 3 0.7295
Beta-secretase 1 P56817 BACE1_HUMAN Homo sapiens 3 0.7295
Regucalcin Q64374 RGN_MOUSE Mus musculus 3 0.7293
Regucalcin Q64374 RGN_MOUSE Mus musculus 3 0.7293
Dihydrofolate reductase P22906 DYR_CANAX Candida albicans 4 0.7293
Dihydrofolate reductase P22906 DYR_CANAX Candida albicans 4 0.7293
Carbonic anhydrase 12 O43570 CAH12_HUMAN Homo sapiens 2 0.7292
Carbonic anhydrase 12 O43570 CAH12_HUMAN Homo sapiens 2 0.7292
Heat shock protein HSP 90-alpha P07900 HS90A_HUMAN Homo sapiens 3 0.7290
Actin-related protein 3 P61157 ARP3_BOVIN Bos taurus 3 0.7290
Actin-related protein 3 P61157 ARP3_BOVIN Bos taurus 3 0.7290
Heat shock protein HSP 90-alpha P07900 HS90A_HUMAN Homo sapiens 3 0.7290
Beta-secretase 1 P56817 BACE1_HUMAN Homo sapiens 2 0.7288
Beta-secretase 1 P56817 BACE1_HUMAN Homo sapiens 2 0.7288
Peroxisome proliferator-activated receptor gamma P37231 PPARG_HUMAN Homo sapiens 2 0.7287
Peroxisome proliferator-activated receptor gamma P37231 PPARG_HUMAN Homo sapiens 2 0.7287
Nitric oxide synthase oxygenase O34453 NOSO_BACSU Bacillus subtilis 3 0.7286
Endoplasmin P41148 ENPL_CANLF Canis lupus familiaris 4 0.7286
Nitric oxide synthase oxygenase O34453 NOSO_BACSU Bacillus subtilis 3 0.7286
Endoplasmin P41148 ENPL_CANLF Canis lupus familiaris 4 0.7286
Serine hydroxymethyltransferase Q7SIB6 Q7SIB6_GEOSE Geobacillus stearothermophilus 3 0.7283
Serine hydroxymethyltransferase Q7SIB6 Q7SIB6_GEOSE Geobacillus stearothermophilus 3 0.7283
Histone deacetylase 8 Q9BY41 HDAC8_HUMAN Homo sapiens 2 0.7282
Histone deacetylase 8 Q9BY41 HDAC8_HUMAN Homo sapiens 2 0.7282
Poly [ADP-ribose] polymerase tankyrase-2 Q9H2K2 TNKS2_HUMAN Homo sapiens 4 0.7279
Poly [ADP-ribose] polymerase tankyrase-2 Q9H2K2 TNKS2_HUMAN Homo sapiens 4 0.7279
Peroxisome proliferator-activated receptor gamma P37231 PPARG_HUMAN Homo sapiens 2 0.7278
Peroxisome proliferator-activated receptor gamma P37231 PPARG_HUMAN Homo sapiens 2 0.7278
Mitogen-activated protein kinase 14 Q16539 MK14_HUMAN Homo sapiens 3 0.7276
Mitogen-activated protein kinase 14 Q16539 MK14_HUMAN Homo sapiens 3 0.7276
Cyclin-dependent kinase 2 P24941 CDK2_HUMAN Homo sapiens 3 0.7274
Ribosyldihydronicotinamide dehydrogenase [quinone] P16083 NQO2_HUMAN Homo sapiens 3 0.7274
Ribosyldihydronicotinamide dehydrogenase [quinone] P16083 NQO2_HUMAN Homo sapiens 3 0.7274
Cyclin-dependent kinase 2 P24941 CDK2_HUMAN Homo sapiens 3 0.7274
Beta-lactamase P00811 AMPC_ECOLI Escherichia coli 3 0.7270
Beta-lactamase P00811 AMPC_ECOLI Escherichia coli 3 0.7270
Prothrombin P00734 THRB_HUMAN Homo sapiens 2 0.7268
Tubulin alpha-1B chain P81947 TBA1B_BOVIN Bos taurus 3 0.7268
Prothrombin P00734 THRB_HUMAN Homo sapiens 2 0.7268
Tetracycline repressor protein class B from transposon Tn10 P04483 TETR2_ECOLX Escherichia coli 2 0.7268
Tubulin alpha-1B chain P81947 TBA1B_BOVIN Bos taurus 3 0.7268
Tetracycline repressor protein class B from transposon Tn10 P04483 TETR2_ECOLX Escherichia coli 2 0.7268
Aminoglycoside N(3)-acetyltransferase A0A3P1UCA6 Q81P86_BACAN Bacillus anthracis 3 0.7266
Aminoglycoside N(3)-acetyltransferase A0A3P1UCA6 Q81P86_BACAN Bacillus anthracis 3 0.7266
Putative N-acetyl glucosaminyl transferase Q6U8B0 Q6U8B0_RAOTE Raoultella terrigena 3 0.7265
Putative N-acetyl glucosaminyl transferase Q6U8B0 Q6U8B0_RAOTE Raoultella terrigena 3 0.7265
Adenylate cyclase type 5 P30803 ADCY5_CANLF Canis lupus familiaris 4 0.7264
Adenylate cyclase type 5 P30803 ADCY5_CANLF Canis lupus familiaris 4 0.7264
Dihydrofolate reductase P0ABQ4 DYR_ECOLI Escherichia coli 3 0.7264
Dihydrofolate reductase P0ABQ4 DYR_ECOLI Escherichia coli 3 0.7264
Prothrombin P00734 THRB_HUMAN Homo sapiens 2 0.7263
Prothrombin P00734 THRB_HUMAN Homo sapiens 2 0.7263
Nuclear receptor ROR-gamma P51449 RORG_HUMAN Homo sapiens 2 0.7261
Nuclear receptor ROR-gamma P51449 RORG_HUMAN Homo sapiens 2 0.7261
Aldo-keto reductase family 1 member C2 P52895 AK1C2_HUMAN Homo sapiens 2 0.7259
Aldo-keto reductase family 1 member C2 P52895 AK1C2_HUMAN Homo sapiens 2 0.7259
Adenosine 5'-monophosphoramidase HINT1 P80912 HINT1_RABIT Oryctolagus cuniculus 3 0.7259
Adenosine 5'-monophosphoramidase HINT1 P80912 HINT1_RABIT Oryctolagus cuniculus 3 0.7259
Capsid protein Q9WBP8 Q9WBP8_9VIRU Adeno-associated virus - 1 2 0.7258
Epidermal growth factor receptor P00533 EGFR_HUMAN Homo sapiens 3 0.7258
Capsid protein Q9WBP8 Q9WBP8_9VIRU Adeno-associated virus - 1 2 0.7258
Epidermal growth factor receptor P00533 EGFR_HUMAN Homo sapiens 3 0.7258
Ribonuclease J H9CZL7 H9CZL7_DEIRD Deinococcus radiodurans 3 0.7257
17beta-hydroxysteroid dehydrogenase O93874 O93874_COCLU Cochliobolus lunatus 3 0.7257
Ribonuclease J H9CZL7 H9CZL7_DEIRD Deinococcus radiodurans 3 0.7257
17beta-hydroxysteroid dehydrogenase O93874 O93874_COCLU Cochliobolus lunatus 3 0.7257
O-GlcNAcase NagJ Q0TR53 OGA_CLOP1 Clostridium perfringens 3 0.7255
Non-receptor tyrosine-protein kinase TYK2 P29597 TYK2_HUMAN Homo sapiens 3 0.7255
O-GlcNAcase NagJ Q0TR53 OGA_CLOP1 Clostridium perfringens 3 0.7255
Non-receptor tyrosine-protein kinase TYK2 P29597 TYK2_HUMAN Homo sapiens 3 0.7255
Nitric oxide synthase, inducible P29477 NOS2_MOUSE Mus musculus 4 0.7253
Nitric oxide synthase, inducible P29477 NOS2_MOUSE Mus musculus 4 0.7253
dTDP-fucosamine acetyltransferase Q8FBQ3 WECD_ECOL6 Escherichia coli O6:H1 3 0.7252
Beta-secretase 1 P56817 BACE1_HUMAN Homo sapiens 2 0.7252
dTDP-fucosamine acetyltransferase Q8FBQ3 WECD_ECOL6 Escherichia coli O6:H1 3 0.7252
Beta-secretase 1 P56817 BACE1_HUMAN Homo sapiens 2 0.7252
Pteridine reductase 1 Q01782 PTR1_LEIMA Leishmania major 2 0.7251
Pteridine reductase 1 Q01782 PTR1_LEIMA Leishmania major 2 0.7251
Avidin P02701 AVID_CHICK Gallus gallus 5 0.7248
Carbonic anhydrase 4 Q64444 CAH4_MOUSE Mus musculus 2 0.7248
Carbonic anhydrase 4 Q64444 CAH4_MOUSE Mus musculus 2 0.7248
Avidin P02701 AVID_CHICK Gallus gallus 5 0.7248
Hypoxanthine-guanine phosphoribosyltransferase P00492 HPRT_HUMAN Homo sapiens 3 0.7247
Hypoxanthine-guanine phosphoribosyltransferase P00492 HPRT_HUMAN Homo sapiens 3 0.7247
Beta-lactamase P00811 AMPC_ECOLI Escherichia coli 3 0.7244
Serine/threonine-protein kinase Chk1 O14757 CHK1_HUMAN Homo sapiens 3 0.7244
Beta-lactamase P00811 AMPC_ECOLI Escherichia coli 3 0.7244
Serine/threonine-protein kinase Chk1 O14757 CHK1_HUMAN Homo sapiens 3 0.7244
Pyridoxal kinase P82197 PDXK_SHEEP Ovis aries 3 0.7243
Pyridoxal kinase P82197 PDXK_SHEEP Ovis aries 3 0.7243
Serine/threonine-protein kinase Chk1 O14757 CHK1_HUMAN Homo sapiens 3 0.7242
Serine/threonine-protein kinase Chk1 O14757 CHK1_HUMAN Homo sapiens 3 0.7242
Abscisic acid receptor PYL2 O80992 PYL2_ARATH Arabidopsis thaliana 2 0.7240
Abscisic acid receptor PYL2 O80992 PYL2_ARATH Arabidopsis thaliana 2 0.7240
Peroxisome proliferator-activated receptor gamma P37231 PPARG_HUMAN Homo sapiens 3 0.7240
Peroxisome proliferator-activated receptor gamma P37231 PPARG_HUMAN Homo sapiens 3 0.7240
Pantothenate kinase P9WPA7 COAA_MYCTU Mycobacterium tuberculosis 3 0.7237
Pantothenate kinase P9WPA7 COAA_MYCTU Mycobacterium tuberculosis 3 0.7237
3-phosphoinositide-dependent protein kinase 1 O15530 PDPK1_HUMAN Homo sapiens 3 0.7234
3-phosphoinositide-dependent protein kinase 1 O15530 PDPK1_HUMAN Homo sapiens 3 0.7234
Transthyretin P02767 TTHY_RAT Rattus norvegicus 2 0.7231
Transthyretin P02767 TTHY_RAT Rattus norvegicus 2 0.7231
Dihydrofolate reductase P0ABQ4 DYR_ECOLI Escherichia coli 3 0.7227
Dihydrofolate reductase P0ABQ4 DYR_ECOLI Escherichia coli 3 0.7227
Tyrosine-protein kinase JAK3 P52333 JAK3_HUMAN Homo sapiens 3 0.7226
Tyrosine-protein kinase JAK3 P52333 JAK3_HUMAN Homo sapiens 3 0.7226
Dihydrofolate reductase P0ABQ4 DYR_ECOLI Escherichia coli 4 0.7224
Dihydrofolate reductase P0ABQ4 DYR_ECOLI Escherichia coli 4 0.7224
Adenylate cyclase type 5 P30803 ADCY5_CANLF Canis lupus familiaris 4 0.7221
Bifunctional dihydrofolate reductase-thymidylate synthase Q07422 DRTS_TOXGO Toxoplasma gondii 3 0.7221
Adenylate cyclase type 5 P30803 ADCY5_CANLF Canis lupus familiaris 4 0.7221
Bifunctional dihydrofolate reductase-thymidylate synthase Q07422 DRTS_TOXGO Toxoplasma gondii 3 0.7221
L-glutamine synthetase Q1QZR8 Q1QZR8_CHRSD Chromohalobacter salexigens 3 0.7220
L-glutamine synthetase Q1QZR8 Q1QZR8_CHRSD Chromohalobacter salexigens 3 0.7220
Cyclic GMP-AMP synthase Q8C6L5 CGAS_MOUSE Mus musculus 3 0.7218
Cyclic GMP-AMP synthase Q8C6L5 CGAS_MOUSE Mus musculus 3 0.7218
Glycogen phosphorylase, liver form P06737 PYGL_HUMAN Homo sapiens 3 0.7218
Glycogen phosphorylase, liver form P06737 PYGL_HUMAN Homo sapiens 3 0.7218
4,4'-diapophytoene synthase A9JQL9 CRTM_STAAU Staphylococcus aureus 2 0.7217
4,4'-diapophytoene synthase A9JQL9 CRTM_STAAU Staphylococcus aureus 2 0.7217
Sulfotransferase 1A1 P50225 ST1A1_HUMAN Homo sapiens 3 0.7215
Sulfotransferase 1A1 P50225 ST1A1_HUMAN Homo sapiens 3 0.7215
Dihydrofolate reductase P00378 DYR_CHICK Gallus gallus 2 0.7214
Dihydrofolate reductase P00378 DYR_CHICK Gallus gallus 2 0.7214
Phospholipase A2, major isoenzyme P00592 PA21B_PIG Sus scrofa 3 0.7212
HTH-type transcriptional regulator QacR P0A0N4 QACR_STAAU Staphylococcus aureus 4 0.7212
Phospholipase A2, major isoenzyme P00592 PA21B_PIG Sus scrofa 3 0.7212
HTH-type transcriptional regulator QacR P0A0N4 QACR_STAAU Staphylococcus aureus 4 0.7212
Gag-Pol polyprotein P12497 POL_HV1N5 Human immunodeficiency virus type 1 group M subtype B 2 0.7211
Gag-Pol polyprotein P12497 POL_HV1N5 Human immunodeficiency virus type 1 group M subtype B 2 0.7211
ATP-dependent molecular chaperone HSP82 P02829 HSP82_YEAST Saccharomyces cerevisiae 2 0.7210
ATP-dependent molecular chaperone HSP82 P02829 HSP82_YEAST Saccharomyces cerevisiae 2 0.7210
Polymerase acidic protein C3W5S0 C3W5S0_I09A0 Influenza A virus 2 0.7208
Polymerase acidic protein C3W5S0 C3W5S0_I09A0 Influenza A virus 2 0.7208
Phenazine biosynthesis protein A/B Q396C9 Q396C9_BURL3 Burkholderia lata 3 0.7207
Phenazine biosynthesis protein A/B Q396C9 Q396C9_BURL3 Burkholderia lata 3 0.7207
Beta-secretase 1 P56817 BACE1_HUMAN Homo sapiens 3 0.7206
Beta-secretase 1 P56817 BACE1_HUMAN Homo sapiens 3 0.7206
Uridine phosphorylase Q5XA29 Q5XA29_STRP6 Streptococcus pyogenes serotype M6 3 0.7204
cGMP-dependent 3',5'-cyclic phosphodiesterase O00408 PDE2A_HUMAN Homo sapiens 3 0.7204
cGMP-dependent 3',5'-cyclic phosphodiesterase O00408 PDE2A_HUMAN Homo sapiens 3 0.7204
Uridine phosphorylase Q5XA29 Q5XA29_STRP6 Streptococcus pyogenes serotype M6 3 0.7204
TetR family transcriptional regulator Q58L87 Q58L87_MYCSM Mycolicibacterium smegmatis 3 0.7203
TetR family transcriptional regulator Q58L87 Q58L87_MYCSM Mycolicibacterium smegmatis 3 0.7203
2',3'-cyclic-nucleotide 3'-phosphodiesterase P16330 CN37_MOUSE Mus musculus 2 0.7202
2',3'-cyclic-nucleotide 3'-phosphodiesterase P16330 CN37_MOUSE Mus musculus 2 0.7202
Gag-Pol polyprotein P12497 POL_HV1N5 Human immunodeficiency virus type 1 group M subtype B 3 0.7201
Gag-Pol polyprotein P12497 POL_HV1N5 Human immunodeficiency virus type 1 group M subtype B 3 0.7201
Dihydrofolate reductase type 1 from Tn4003 P13955 DYRA_STAAU Staphylococcus aureus 3 0.7198
Dihydrofolate reductase type 1 from Tn4003 P13955 DYRA_STAAU Staphylococcus aureus 3 0.7198
Queuine tRNA-ribosyltransferase P28720 TGT_ZYMMO Zymomonas mobilis subsp. mobilis 2 0.7191
Queuine tRNA-ribosyltransferase P28720 TGT_ZYMMO Zymomonas mobilis subsp. mobilis 2 0.7191
Phospholipase A2, major isoenzyme P00592 PA21B_PIG Sus scrofa 3 0.7189
Phospholipase A2, major isoenzyme P00592 PA21B_PIG Sus scrofa 3 0.7189
Dihydrofolate reductase P00375 DYR_MOUSE Mus musculus 4 0.7188
Dihydrofolate reductase P00375 DYR_MOUSE Mus musculus 4 0.7188
Probable NDP-rhamnosyltransferase Q9ALM8 Q9ALM8_SACSN Saccharopolyspora spinosa 2 0.7186
Probable NDP-rhamnosyltransferase Q9ALM8 Q9ALM8_SACSN Saccharopolyspora spinosa 2 0.7186
Streptavidin P22629 SAV_STRAV Streptomyces avidinii 3 0.7183
Ribosyldihydronicotinamide dehydrogenase [quinone] P16083 NQO2_HUMAN Homo sapiens 2 0.7183
Streptavidin P22629 SAV_STRAV Streptomyces avidinii 3 0.7183
Ribosyldihydronicotinamide dehydrogenase [quinone] P16083 NQO2_HUMAN Homo sapiens 2 0.7183
Cyclin-dependent kinase 2 P24941 CDK2_HUMAN Homo sapiens 3 0.7182
Cyclin-dependent kinase 2 P24941 CDK2_HUMAN Homo sapiens 3 0.7182
Chalcone--flavanone isomerase 1 P28012 CFI1_MEDSA Medicago sativa 3 0.7181
Chalcone--flavanone isomerase 1 P28012 CFI1_MEDSA Medicago sativa 3 0.7181
Mitogen-activated protein kinase 14 Q16539 MK14_HUMAN Homo sapiens 3 0.7179
Mitogen-activated protein kinase 14 Q16539 MK14_HUMAN Homo sapiens 3 0.7179
Vitamin D3 receptor A Q9PTN2 VDRA_DANRE Danio rerio 4 0.7178
Mitochondrial poly(A) polymerase F1NBW0 F1NBW0_CHICK Gallus gallus 2 0.7178
Mitochondrial poly(A) polymerase F1NBW0 F1NBW0_CHICK Gallus gallus 2 0.7178
Vitamin D3 receptor A Q9PTN2 VDRA_DANRE Danio rerio 4 0.7178
cGMP-dependent protein kinase 1 Q13976 KGP1_HUMAN Homo sapiens 3 0.7174
cGMP-dependent protein kinase 1 Q13976 KGP1_HUMAN Homo sapiens 3 0.7174
Poly [ADP-ribose] polymerase 1 P09874 PARP1_HUMAN Homo sapiens 3 0.7173
Poly [ADP-ribose] polymerase 1 P09874 PARP1_HUMAN Homo sapiens 3 0.7173
Tetracycline repressor protein class D P0ACT4 TETR4_ECOLX Escherichia coli 3 0.7172
Tetracycline repressor protein class D P0ACT4 TETR4_ECOLX Escherichia coli 3 0.7172
HTH-type transcriptional repressor PurR P0ACP7 PURR_ECOLI Escherichia coli 3 0.7171
cAMP-dependent protein kinase catalytic subunit alpha P00517 KAPCA_BOVIN Bos taurus 3 0.7171
HTH-type transcriptional repressor PurR P0ACP7 PURR_ECOLI Escherichia coli 3 0.7171
Endothiapepsin P11838 CARP_CRYPA Cryphonectria parasitica 3 0.7171
Death-associated protein kinase 1 P53355 DAPK1_HUMAN Homo sapiens 3 0.7171
cAMP-dependent protein kinase catalytic subunit alpha P00517 KAPCA_BOVIN Bos taurus 3 0.7171
Endothiapepsin P11838 CARP_CRYPA Cryphonectria parasitica 3 0.7171
Death-associated protein kinase 1 P53355 DAPK1_HUMAN Homo sapiens 3 0.7171
Biotin carboxylase P24182 ACCC_ECOLI Escherichia coli 4 0.7170
Biotin carboxylase P24182 ACCC_ECOLI Escherichia coli 4 0.7170
1-deoxy-D-xylulose 5-phosphate reductoisomerase P45568 DXR_ECOLI Escherichia coli 2 0.7166
Tyrosine-protein kinase SYK P43405 KSYK_HUMAN Homo sapiens 4 0.7166
Tyrosine-protein kinase SYK P43405 KSYK_HUMAN Homo sapiens 4 0.7166
1-deoxy-D-xylulose 5-phosphate reductoisomerase P45568 DXR_ECOLI Escherichia coli 2 0.7166
Sulfotransferase 2A1 Q06520 ST2A1_HUMAN Homo sapiens 2 0.7164
Norsolorinic acid synthase Q12053 AFLC_ASPPU Aspergillus parasiticus 2 0.7164
Sulfotransferase 2A1 Q06520 ST2A1_HUMAN Homo sapiens 2 0.7164
Norsolorinic acid synthase Q12053 AFLC_ASPPU Aspergillus parasiticus 2 0.7164
Abscisic acid receptor PYL1 Q8VZS8 PYL1_ARATH Arabidopsis thaliana 2 0.7164
Abscisic acid receptor PYL1 Q8VZS8 PYL1_ARATH Arabidopsis thaliana 2 0.7164
Nitric oxide synthase 1 P29476 NOS1_RAT Rattus norvegicus 4 0.7163
Nitric oxide synthase 1 P29476 NOS1_RAT Rattus norvegicus 4 0.7163
UDP-galactopyranose mutase Q48485 GLF1_KLEPN Klebsiella pneumoniae 3 0.7163
UDP-galactopyranose mutase Q48485 GLF1_KLEPN Klebsiella pneumoniae 3 0.7163
L-lactate dehydrogenase A chain P04642 LDHA_RAT Rattus norvegicus 3 0.7161
L-lactate dehydrogenase A chain P04642 LDHA_RAT Rattus norvegicus 3 0.7161
Anthocyanidin 3-O-glucosyltransferase UFGT P51094 UFOG_VITVI Vitis vinifera 3 0.7158
Anthocyanidin 3-O-glucosyltransferase UFGT P51094 UFOG_VITVI Vitis vinifera 3 0.7158
Gag-Pol polyprotein P03367 POL_HV1BR Human immunodeficiency virus type 1 group M subtype B 3 0.7157
Gag-Pol polyprotein P03367 POL_HV1BR Human immunodeficiency virus type 1 group M subtype B 3 0.7157
cAMP-dependent protein kinase type II-beta regulatory subunit P12369 KAP3_RAT Rattus norvegicus 3 0.7156
cAMP-dependent protein kinase type II-beta regulatory subunit P12369 KAP3_RAT Rattus norvegicus 3 0.7156
Tetracycline repressor protein class D P0ACT4 TETR4_ECOLX Escherichia coli 3 0.7153
DNA gyrase subunit B Q839Z1 GYRB_ENTFA Enterococcus faecalis 3 0.7153
DNA gyrase subunit B Q839Z1 GYRB_ENTFA Enterococcus faecalis 3 0.7153
Tetracycline repressor protein class D P0ACT4 TETR4_ECOLX Escherichia coli 3 0.7153
Serine endoprotease DegS P0AEE3 DEGS_ECOLI Escherichia coli 4 0.7151
Serine endoprotease DegS P0AEE3 DEGS_ECOLI Escherichia coli 4 0.7151
Mitogen-activated protein kinase 14 Q16539 MK14_HUMAN Homo sapiens 3 0.7149
Mitogen-activated protein kinase 14 Q16539 MK14_HUMAN Homo sapiens 3 0.7149
Adenylate cyclase type 5 P30803 ADCY5_CANLF Canis lupus familiaris 3 0.7148
Adenylate cyclase type 5 P30803 ADCY5_CANLF Canis lupus familiaris 3 0.7148
Endoplasmin P41148 ENPL_CANLF Canis lupus familiaris 2 0.7147
Endoplasmin P41148 ENPL_CANLF Canis lupus familiaris 2 0.7147
Transthyretin Q9PTT3 Q9PTT3_SPAAU Sparus aurata 3 0.7146
Transthyretin Q9PTT3 Q9PTT3_SPAAU Sparus aurata 3 0.7146
Disintegrin and metalloproteinase domain-containing protein 17 P78536 ADA17_HUMAN Homo sapiens 4 0.7144
Disintegrin and metalloproteinase domain-containing protein 17 P78536 ADA17_HUMAN Homo sapiens 4 0.7144
11-beta-hydroxysteroid dehydrogenase 1 P28845 DHI1_HUMAN Homo sapiens 3 0.7141
11-beta-hydroxysteroid dehydrogenase 1 P28845 DHI1_HUMAN Homo sapiens 3 0.7141
Nitric oxide synthase 1 P29476 NOS1_RAT Rattus norvegicus 4 0.7139
Nitric oxide synthase 1 P29476 NOS1_RAT Rattus norvegicus 4 0.7139
Queuine tRNA-ribosyltransferase P28720 TGT_ZYMMO Zymomonas mobilis subsp. mobilis 3 0.7136
Queuine tRNA-ribosyltransferase P28720 TGT_ZYMMO Zymomonas mobilis subsp. mobilis 3 0.7136
Tetracycline repressor protein class D P0ACT4 TETR4_ECOLX Escherichia coli 2 0.7135
Tetracycline repressor protein class D P0ACT4 TETR4_ECOLX Escherichia coli 2 0.7135
Mycocyclosin synthase P9WPP7 CP121_MYCTU Mycobacterium tuberculosis 2 0.7133
Mycocyclosin synthase P9WPP7 CP121_MYCTU Mycobacterium tuberculosis 2 0.7133
Mitogen-activated protein kinase 1 P63086 MK01_RAT Rattus norvegicus 3 0.7132
ADP-ribosylation factor 1 P84080 ARF1_BOVIN Bos taurus 2 0.7132
Mitogen-activated protein kinase 1 P63086 MK01_RAT Rattus norvegicus 3 0.7132
ADP-ribosylation factor 1 P84080 ARF1_BOVIN Bos taurus 2 0.7132
tRNA-guanine(15) transglycosylase O58843 ATGT_PYRHO Pyrococcus horikoshii 3 0.7131
Heat shock protein HSP 90-alpha P07900 HS90A_HUMAN Homo sapiens 3 0.7131
tRNA-guanine(15) transglycosylase O58843 ATGT_PYRHO Pyrococcus horikoshii 3 0.7131
Heat shock protein HSP 90-alpha P07900 HS90A_HUMAN Homo sapiens 3 0.7131
Prothrombin P00734 THRB_HUMAN Homo sapiens 3 0.7125
Prothrombin P00734 THRB_HUMAN Homo sapiens 3 0.7125
6-phosphogluconate dehydrogenase, decarboxylating P96789 6PGD_LACLM Lactococcus lactis subsp. cremoris 3 0.7125
6-phosphogluconate dehydrogenase, decarboxylating P96789 6PGD_LACLM Lactococcus lactis subsp. cremoris 3 0.7125
Basic phospholipase A2 VRV-PL-VIIIa P59071 PA2B8_DABRR Daboia russelii 2 0.7124
Basic phospholipase A2 VRV-PL-VIIIa P59071 PA2B8_DABRR Daboia russelii 2 0.7124
Dihydrofolate reductase P00374 DYR_HUMAN Homo sapiens 3 0.7123
Dihydrofolate reductase P00374 DYR_HUMAN Homo sapiens 3 0.7123
Vitamin D3 receptor P13053 VDR_RAT Rattus norvegicus 4 0.7120
Aldo-keto reductase family 1 member C2 P52895 AK1C2_HUMAN Homo sapiens 2 0.7120
Aldo-keto reductase family 1 member C2 P52895 AK1C2_HUMAN Homo sapiens 2 0.7120
Vitamin D3 receptor P13053 VDR_RAT Rattus norvegicus 4 0.7120
Mycocyclosin synthase P9WPP7 CP121_MYCTU Mycobacterium tuberculosis 3 0.7119
Mycocyclosin synthase P9WPP7 CP121_MYCTU Mycobacterium tuberculosis 3 0.7119
Type IV / VI secretion system DotU domain-containing protein Q9KN50 Q9KN50_VIBCH Vibrio cholerae serotype O1 2 0.7113
Type IV / VI secretion system DotU domain-containing protein Q9KN50 Q9KN50_VIBCH Vibrio cholerae serotype O1 2 0.7113
Casein kinase I isoform gamma-3 Q9Y6M4 KC1G3_HUMAN Homo sapiens 3 0.7112
Casein kinase I isoform gamma-3 Q9Y6M4 KC1G3_HUMAN Homo sapiens 3 0.7112
Subunit alpha of sarocosine oxidase Q50LF0 Q50LF0_9CORY Corynebacterium sp. U-96 3 0.7111
Subunit alpha of sarocosine oxidase Q50LF0 Q50LF0_9CORY Corynebacterium sp. U-96 3 0.7111
Prothrombin P00734 THRB_HUMAN Homo sapiens 3 0.7110
Prothrombin P00734 THRB_HUMAN Homo sapiens 3 0.7110
Epothilone C/D epoxidase Q9KIZ4 C167_SORCE Sorangium cellulosum 2 0.7108
Epothilone C/D epoxidase Q9KIZ4 C167_SORCE Sorangium cellulosum 2 0.7108
Streptogramin A acetyltransferase P50870 VATD_ENTFC Enterococcus faecium 2 0.7106
Streptogramin A acetyltransferase P50870 VATD_ENTFC Enterococcus faecium 2 0.7106
Dihydropteroate synthase Q81VW8 Q81VW8_BACAN Bacillus anthracis 3 0.7106
Dihydropteroate synthase Q81VW8 Q81VW8_BACAN Bacillus anthracis 3 0.7106
F420-dependent methylenetetrahydromethanopterin dehydrogenase P94951 MTD_METKA Methanopyrus kandleri 2 0.7104
F420-dependent methylenetetrahydromethanopterin dehydrogenase P94951 MTD_METKA Methanopyrus kandleri 2 0.7104
Camphor 5-monooxygenase P00183 CPXA_PSEPU Pseudomonas putida 3 0.7103
Camphor 5-monooxygenase P00183 CPXA_PSEPU Pseudomonas putida 3 0.7103
Enoyl-ACP reductase Q9BJJ9 Q9BJJ9_PLAFA Plasmodium falciparum 4 0.7101
Enoyl-ACP reductase Q9BJJ9 Q9BJJ9_PLAFA Plasmodium falciparum 4 0.7101
cGMP-dependent protein kinase 1 Q13976 KGP1_HUMAN Homo sapiens 3 0.7097
cGMP-dependent protein kinase 1 Q13976 KGP1_HUMAN Homo sapiens 3 0.7097
Cyclin-dependent kinase 2 P24941 CDK2_HUMAN Homo sapiens 3 0.7095
Cyclin-dependent kinase 2 P24941 CDK2_HUMAN Homo sapiens 3 0.7095
Gag-Pol polyprotein P12497 POL_HV1N5 Human immunodeficiency virus type 1 group M subtype B 3 0.7094
Gag-Pol polyprotein P12497 POL_HV1N5 Human immunodeficiency virus type 1 group M subtype B 3 0.7094
Serine/threonine-protein kinase pim-1 P11309 PIM1_HUMAN Homo sapiens 2 0.7092
Serine/threonine-protein kinase pim-1 P11309 PIM1_HUMAN Homo sapiens 2 0.7092
Catechol O-methyltransferase P22734 COMT_RAT Rattus norvegicus 3 0.7086
Serine/threonine-protein kinase Chk1 O14757 CHK1_HUMAN Homo sapiens 3 0.7086
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase Q8ZMF7 ISPF_SALTY Salmonella typhimurium 3 0.7086
Catechol O-methyltransferase P22734 COMT_RAT Rattus norvegicus 3 0.7086
Serine/threonine-protein kinase Chk1 O14757 CHK1_HUMAN Homo sapiens 3 0.7086
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase Q8ZMF7 ISPF_SALTY Salmonella typhimurium 3 0.7086
Cyclin-dependent kinase 2 P24941 CDK2_HUMAN Homo sapiens 3 0.7085
Cyclin-dependent kinase 2 P24941 CDK2_HUMAN Homo sapiens 3 0.7085
17beta-hydroxysteroid dehydrogenase O93874 O93874_COCLU Cochliobolus lunatus 4 0.7083
Focal adhesion kinase 1 Q05397 FAK1_HUMAN Homo sapiens 3 0.7083
17beta-hydroxysteroid dehydrogenase O93874 O93874_COCLU Cochliobolus lunatus 4 0.7083
Focal adhesion kinase 1 Q05397 FAK1_HUMAN Homo sapiens 3 0.7083
Polymerase basic protein 2 P31345 PB2_I75A3 Influenza A virus 2 0.7076
Polymerase basic protein 2 P31345 PB2_I75A3 Influenza A virus 2 0.7076
Glycylpeptide N-tetradecanoyltransferase Q4Q5S8 Q4Q5S8_LEIMA Leishmania major 3 0.7075
Glycylpeptide N-tetradecanoyltransferase Q4Q5S8 Q4Q5S8_LEIMA Leishmania major 3 0.7075
Beta-1 adrenergic receptor P07700 ADRB1_MELGA Meleagris gallopavo 2 0.7071
Beta-1 adrenergic receptor P07700 ADRB1_MELGA Meleagris gallopavo 2 0.7071
Phospholipase A2, major isoenzyme P00592 PA21B_PIG Sus scrofa 3 0.7070
Liver carboxylesterase 1 P23141 EST1_HUMAN Homo sapiens 2 0.7070
Liver carboxylesterase 1 P23141 EST1_HUMAN Homo sapiens 2 0.7070
Phospholipase A2, major isoenzyme P00592 PA21B_PIG Sus scrofa 3 0.7070
Histidine kinase 4 Q9C5U0 AHK4_ARATH Arabidopsis thaliana 3 0.7069
Histidine kinase 4 Q9C5U0 AHK4_ARATH Arabidopsis thaliana 3 0.7069
Mitogen-activated protein kinase 14 Q16539 MK14_HUMAN Homo sapiens 2 0.7066
Thymidylate synthase P45352 TYSY_RAT Rattus norvegicus 2 0.7066
Mitogen-activated protein kinase 14 Q16539 MK14_HUMAN Homo sapiens 2 0.7066
Thymidylate synthase P45352 TYSY_RAT Rattus norvegicus 2 0.7066
Cyclin-dependent kinase 9 P50750 CDK9_HUMAN Homo sapiens 3 0.7064
Cyclin-dependent kinase 9 P50750 CDK9_HUMAN Homo sapiens 3 0.7064
Aldo-keto reductase family 1 member C3 P42330 AK1C3_HUMAN Homo sapiens 2 0.7064
Aldo-keto reductase family 1 member C3 P42330 AK1C3_HUMAN Homo sapiens 2 0.7064
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase Q3JRA0 ISPF_BURP1 Burkholderia pseudomallei 3 0.7063
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase Q3JRA0 ISPF_BURP1 Burkholderia pseudomallei 3 0.7063
Gag-Pol polyprotein P04584 POL_HV2RO Human immunodeficiency virus type 2 subtype A 3 0.7062
Gag-Pol polyprotein P04584 POL_HV2RO Human immunodeficiency virus type 2 subtype A 3 0.7062
Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial Q8N5Z0 AADAT_HUMAN Homo sapiens 2 0.7060
Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial Q8N5Z0 AADAT_HUMAN Homo sapiens 2 0.7060
Tetracycline repressor protein class D P0ACT4 TETR4_ECOLX Escherichia coli 3 0.7059
Tetracycline repressor protein class D P0ACT4 TETR4_ECOLX Escherichia coli 3 0.7059
Tannase B3Y018 B3Y018_LACPN Lactiplantibacillus plantarum 3 0.7058
Tannase B3Y018 B3Y018_LACPN Lactiplantibacillus plantarum 3 0.7058
Nitric oxide synthase 1 P29476 NOS1_RAT Rattus norvegicus 3 0.7058
Nitric oxide synthase 1 P29476 NOS1_RAT Rattus norvegicus 3 0.7058
Amino-acid acetyltransferase Q5FAK7 Q5FAK7_NEIG1 Neisseria gonorrhoeae 2 0.7055
Amino-acid acetyltransferase Q5FAK7 Q5FAK7_NEIG1 Neisseria gonorrhoeae 2 0.7055
Cyclin-dependent kinase 2 P24941 CDK2_HUMAN Homo sapiens 3 0.7053
Cyclin-dependent kinase 2 P24941 CDK2_HUMAN Homo sapiens 3 0.7053
Cyclin-dependent kinase 5 Q00535 CDK5_HUMAN Homo sapiens 3 0.7051
Cyclin-dependent kinase 5 Q00535 CDK5_HUMAN Homo sapiens 3 0.7051
Prothrombin P00734 THRB_HUMAN Homo sapiens 3 0.7049
Prothrombin P00734 THRB_HUMAN Homo sapiens 3 0.7049
cAMP-dependent protein kinase catalytic subunit alpha P00517 KAPCA_BOVIN Bos taurus 3 0.7048
cAMP-dependent protein kinase catalytic subunit alpha P00517 KAPCA_BOVIN Bos taurus 3 0.7048
Nitric oxide synthase 1 P29476 NOS1_RAT Rattus norvegicus 4 0.7047
Nitric oxide synthase 1 P29476 NOS1_RAT Rattus norvegicus 4 0.7047
Gag-Pol polyprotein P03367 POL_HV1BR Human immunodeficiency virus type 1 group M subtype B 3 0.7046
Purine nucleoside phosphorylase DeoD-type O34925 DEOD_BACSU Bacillus subtilis 3 0.7046
Gag-Pol polyprotein P03367 POL_HV1BR Human immunodeficiency virus type 1 group M subtype B 3 0.7046
Purine nucleoside phosphorylase DeoD-type O34925 DEOD_BACSU Bacillus subtilis 3 0.7046
Cyclin-dependent kinase 2 P24941 CDK2_HUMAN Homo sapiens 3 0.7045
Cyclin-dependent kinase 2 P24941 CDK2_HUMAN Homo sapiens 3 0.7045
Prothrombin P00734 THRB_HUMAN Homo sapiens 3 0.7044
Prothrombin P00734 THRB_HUMAN Homo sapiens 3 0.7044
Diamine acetyltransferase 1 P21673 SAT1_HUMAN Homo sapiens 2 0.7044
Diamine acetyltransferase 1 P21673 SAT1_HUMAN Homo sapiens 2 0.7044
Gag-Pol polyprotein P12497 POL_HV1N5 Human immunodeficiency virus type 1 group M subtype B 3 0.7043
Gag-Pol polyprotein P12497 POL_HV1N5 Human immunodeficiency virus type 1 group M subtype B 3 0.7043
Dihydrofolate reductase P00374 DYR_HUMAN Homo sapiens 4 0.7041
Serine/threonine-protein kinase pim-1 P11309 PIM1_HUMAN Homo sapiens 3 0.7041
Dihydrofolate reductase P00374 DYR_HUMAN Homo sapiens 4 0.7041
Serine/threonine-protein kinase pim-1 P11309 PIM1_HUMAN Homo sapiens 3 0.7041
HTH-type transcriptional regulator QacR P0A0N4 QACR_STAAU Staphylococcus aureus 3 0.7038
HTH-type transcriptional regulator QacR P0A0N4 QACR_STAAU Staphylococcus aureus 3 0.7038
ABC-type polar amino acid transport system, ATPase component Q8RCC2 Q8RCC2_CALS4 Caldanaerobacter subterraneus subsp. tengcongensis 2 0.7036
ABC-type polar amino acid transport system, ATPase component Q8RCC2 Q8RCC2_CALS4 Caldanaerobacter subterraneus subsp. tengcongensis 2 0.7036
Enoyl-ACP reductase Q9BH77 Q9BH77_PLAFA Plasmodium falciparum 3 0.7031
Carbonic anhydrase Q39588 Q39588_CHLRE Chlamydomonas reinhardtii 2 0.7031
Enoyl-ACP reductase Q9BH77 Q9BH77_PLAFA Plasmodium falciparum 3 0.7031
Carbonic anhydrase Q39588 Q39588_CHLRE Chlamydomonas reinhardtii 2 0.7031
Beta-galactoside-specific lectin 4 Q6ITZ3 ML4_VISAL Viscum album 2 0.7027
Prothrombin P00734 THRB_HUMAN Homo sapiens 2 0.7027
Beta-galactoside-specific lectin 4 Q6ITZ3 ML4_VISAL Viscum album 2 0.7027
Prothrombin P00734 THRB_HUMAN Homo sapiens 2 0.7027
Fructose-1,6-bisphosphatase 1 P09467 F16P1_HUMAN Homo sapiens 2 0.7023
Fructose-1,6-bisphosphatase 1 P09467 F16P1_HUMAN Homo sapiens 2 0.7023
Beta-lactamase Q9L5C8 Q9L5C8_ECOLX Escherichia coli 3 0.7023
Beta-lactamase Q9L5C8 Q9L5C8_ECOLX Escherichia coli 3 0.7023
Major strawberry allergen Fra a 1-3 D0E0C7 FRA13_FRAAN Fragaria ananassa 3 0.7021
Peroxisome proliferator-activated receptor alpha Q07869 PPARA_HUMAN Homo sapiens 2 0.7021
Major strawberry allergen Fra a 1-3 D0E0C7 FRA13_FRAAN Fragaria ananassa 3 0.7021
Peroxisome proliferator-activated receptor alpha Q07869 PPARA_HUMAN Homo sapiens 2 0.7021
Cytosolic purine 5'-nucleotidase P49902 5NTC_HUMAN Homo sapiens 2 0.7020
ATP-dependent molecular chaperone HSP82 P02829 HSP82_YEAST Saccharomyces cerevisiae 3 0.7020
Cytosolic purine 5'-nucleotidase P49902 5NTC_HUMAN Homo sapiens 2 0.7020
ATP-dependent molecular chaperone HSP82 P02829 HSP82_YEAST Saccharomyces cerevisiae 3 0.7020
Cyclin-dependent kinase 2 P24941 CDK2_HUMAN Homo sapiens 4 0.7017
Cyclin-dependent kinase 2 P24941 CDK2_HUMAN Homo sapiens 4 0.7017
Vitamin D3 receptor P13053 VDR_RAT Rattus norvegicus 4 0.7016
Vitamin D3 receptor P13053 VDR_RAT Rattus norvegicus 4 0.7016
Thymidylate synthase P00469 TYSY_LACCA Lacticaseibacillus casei 2 0.7014
Thymidylate synthase P00469 TYSY_LACCA Lacticaseibacillus casei 2 0.7014
Avidin P02701 AVID_CHICK Gallus gallus 2 0.7014
Avidin P02701 AVID_CHICK Gallus gallus 2 0.7014
Tetracycline repressor protein class D P0ACT4 TETR4_ECOLX Escherichia coli 3 0.7012
Tetracycline repressor protein class D P0ACT4 TETR4_ECOLX Escherichia coli 3 0.7012
WxcM-like protein Q12KT8 Q12KT8_SHEDO Shewanella denitrificans 3 0.7011
WxcM-like protein Q12KT8 Q12KT8_SHEDO Shewanella denitrificans 3 0.7011
Acetolactate synthase, chloroplastic P17597 ILVB_ARATH Arabidopsis thaliana 2 0.7003
Acetolactate synthase, chloroplastic P17597 ILVB_ARATH Arabidopsis thaliana 2 0.7003
Polymerase acidic protein C3W5S0 C3W5S0_I09A0 Influenza A virus 2 0.7003
Polymerase acidic protein C3W5S0 C3W5S0_I09A0 Influenza A virus 2 0.7003
Mitogen-activated protein kinase 14 P47811 MK14_MOUSE Mus musculus 4 0.7002
Mitogen-activated protein kinase 14 P47811 MK14_MOUSE Mus musculus 4 0.7002
NAD-dependent protein deacetylase sirtuin-3, mitochondrial Q9NTG7 SIR3_HUMAN Homo sapiens 4 0.7001
Cyclin-dependent kinase 2 P24941 CDK2_HUMAN Homo sapiens 4 0.7001
Cyclin-dependent kinase 2 P24941 CDK2_HUMAN Homo sapiens 4 0.7001
NAD-dependent protein deacetylase sirtuin-3, mitochondrial Q9NTG7 SIR3_HUMAN Homo sapiens 4 0.7001
3-hydroxyanthranilate 3,4-dioxygenase Q1LCS4 3HAO_CUPMC Cupriavidus metallidurans 2 0.7000
3-hydroxyanthranilate 3,4-dioxygenase Q1LCS4 3HAO_CUPMC Cupriavidus metallidurans 2 0.7000

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