Elgonene J - Compound Card

Elgonene J

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Elgonene J

Structure
Zoomed Structure
  • Family: Fungi - Hymenochaetaceae
  • Kingdom: Fungi
  • Class: Terpenoid
    • Subclass: Sesquiterpene
Canonical Smiles C=C1CCC[C@@]([C@@H]1CCc1cocc1)(C)C(=O)O
InChI InChI=1S/C15H20O3/c1-11-4-3-8-15(2,14(16)17)13(11)6-5-12-7-9-18-10-12/h7,9-10,13H,1,3-6,8H2,2H3,(H,16,17)/t13-,15-/m1/s1
InChIKey YVAMNJAWJAORRC-UKRRQHHQSA-N
Formula C15H20O3
HBA 2
HBD 1
MW 248.32
Rotatable Bonds 4
TPSA 50.44
LogP 3.66
Number Rings 2
Number Aromatic Rings 1
Heavy Atom Count 18
Formal Charge 0
Fraction CSP3 0.53
Exact Mass 248.14
Number of Lipinski Rule Violations 0
# Species Family Kingdom NCBI Taxonomy ID
1 Sanghuangporus sp. Hymenochaetaceae Fungi 2267874

Showing of synonyms

  • Cheng T, Chepkirui C, et al. (2019). Sesquiterpenes from an Eastern African medicinal mushroom belonging to the genus Sanghuangporus.. Journal of Natural Products,2019,82(5),1283-1291.. [View] [PubMed]
Pubchem: 155539245

No compound-protein relationship available.

Structure

SMILES: C1CCCC(C1=C)CCc2ccoc2

Level: 1

Mol. Weight: 248.32 g/mol

Structure

SMILES: C=C1CCCCC1

Level: 0

Mol. Weight: 248.32 g/mol

Structure

SMILES: c1ccoc1

Level: 0

Mol. Weight: 248.32 g/mol

Antimicrobial

Absorption

Caco-2 (logPapp)
-4.49
Human Oral Bioavailability 20%
Bioavailable
Human Intestinal Absorption
Absorbed
Madin-Darby Canine Kidney
-4.5
Human Oral Bioavailability 50%
Bioavailable
P-Glycoprotein Inhibitor
Non-Inhibitor
P-Glycoprotein Substrate
Non-Substrate
Skin Permeability
-2.54

Distribution

Blood-Brain Barrier (CNS)
-
Blood-Brain Barrier
Penetrable
Fraction Unbound (Human)
0.81
Plasma Protein Binding
72.75
Steady State Volume of Distribution
-

Metabolism

Breast Cancer Resistance Protein
Non-Inhibitor
CYP 1A2 Inhibitor
Non-Inhibitor
CYP 1A2 Substrate
Non-Substrate
CYP 2C19 Inhibitor
Non-Inhibitor
CYP 2C19 Substrate
Non-Substrate
CYP 2C9 Inhibitor
Non-Inhibitor
CYP 2C9 Substrate
Substrate
CYP 2D6 Inhibitor
Non-Inhibitor
CYP 2D6 Substrate
Non-Substrate
CYP 3A4 Inhibitor
Non-Inhibitor
CYP 3A4 Substrate
Substrate
OATP1B1
Non-Inhibitor
OATP1B3
Non-Inhibitor

Excretion

Clearance
2.09
Organic Cation Transporter 2
Non-Inhibitor
Half-Life of Drug
-

Toxicity

AMES Mutagenesis
Safe
Avian
Safe
Bee
Toxic
Bioconcentration Factor
0.48
Biodegradation
Safe
Carcinogenesis
Toxic
Crustacean
Safe
Liver Injury I (DILI)
Safe
Eye Corrosion
Safe
Eye Irritation
Toxic
Maximum Tolerated Dose
-0.24
Liver Injury II
Toxic
hERG Blockers
Safe
Daphnia Maga
3.06
Micronucleos
Safe
NR-AhR
Safe
NR-AR
Safe
NR-AR-LBD
Safe
NR-Aromatase
Safe
NR-ER
Safe
NR-ER-LBD
Safe
NR-GR
Safe
NR-PPAR-gamma
Safe
NR-TR
Safe
T. Pyriformis
1.24
Rat (Acute)
2.98
Rat (Chronic Oral)
2.41
Fathead Minnow
3.93
Respiratory Disease
Toxic
Skin Sensitisation
Toxic
SR-ARE
Safe
SR-ATAD5
Safe
SR-HSE
Safe
SR-MMP
Safe
SR-p53
Safe

General Properties

Boiling Point
312.17
Hydration Free Energy
-7.5
Log(D) at pH=7.4
0.42
Log(P)
3.91
Log S
-3.93
Log(Vapor Pressure)
-6.59
Melting Point
76.95
pKa Acid
5.03
pKa Basic
7.47
Protein Name UniProt ID Entry Name Species #Pharmacophore Points Probability (0.7 ≤ Tversky Score ≤ 1.0)
Cytochrome P450 S6BVH1 S6BVH1_RHOER Rhodococcus erythropolis 3 0.9776
Cytochrome P450 S6BVH1 S6BVH1_RHOER Rhodococcus erythropolis 3 0.9776
Metallophosphoesterase A3DJ38 A3DJ38_HUNT2 Clostridium thermocellum 3 0.9516
Metallophosphoesterase A3DJ38 A3DJ38_HUNT2 Clostridium thermocellum 3 0.9516
Branched-chain-amino-acid aminotransferase, mitochondrial O15382 BCAT2_HUMAN Homo sapiens 3 0.9414
Branched-chain-amino-acid aminotransferase, mitochondrial O15382 BCAT2_HUMAN Homo sapiens 3 0.9414
Soluble acetylcholine receptor Q8WSF8 Q8WSF8_APLCA Aplysia californica 3 0.9394
Soluble acetylcholine receptor Q8WSF8 Q8WSF8_APLCA Aplysia californica 3 0.9394
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 P04191 AT2A1_RABIT Oryctolagus cuniculus 3 0.9379
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 P04191 AT2A1_RABIT Oryctolagus cuniculus 3 0.9379
Deacetoxycephalosporin C synthase P18548 CEFE_STRCL Streptomyces clavuligerus 3 0.9352
Deacetoxycephalosporin C synthase P18548 CEFE_STRCL Streptomyces clavuligerus 3 0.9352
Protein LlR18A P52778 L18A_LUPLU Lupinus luteus 3 0.9270
Protein LlR18A P52778 L18A_LUPLU Lupinus luteus 3 0.9270
Retinoic acid receptor RXR-alpha P19793 RXRA_HUMAN Homo sapiens 3 0.9237
Retinoic acid receptor RXR-alpha P19793 RXRA_HUMAN Homo sapiens 3 0.9237
Phytohormone-binding protein CSBP A0A1S3THR8 PHBP_VIGRR Vigna radiata var. radiata 3 0.9186
Phytohormone-binding protein CSBP A0A1S3THR8 PHBP_VIGRR Vigna radiata var. radiata 3 0.9186
Mycinamicin III 3''-O-methyltransferase Q49492 MYCF_MICGR Micromonospora griseorubida 2 0.9169
Mycinamicin III 3''-O-methyltransferase Q49492 MYCF_MICGR Micromonospora griseorubida 2 0.9169
Polymerase basic protein 2 P31345 PB2_I75A3 Influenza A virus 3 0.9133
Polymerase basic protein 2 P31345 PB2_I75A3 Influenza A virus 3 0.9133
3',5'-cyclic-AMP phosphodiesterase 4D Q08499 PDE4D_HUMAN Homo sapiens 3 0.9130
3',5'-cyclic-AMP phosphodiesterase 4D Q08499 PDE4D_HUMAN Homo sapiens 3 0.9130
Phenylpyruvate C(3)-methyltransferase Q643C8 MPPJ_STRHY Streptomyces hygroscopicus 3 0.9086
Phenylpyruvate C(3)-methyltransferase Q643C8 MPPJ_STRHY Streptomyces hygroscopicus 3 0.9086
3',5'-cyclic-AMP phosphodiesterase 4D Q08499 PDE4D_HUMAN Homo sapiens 3 0.9038
3',5'-cyclic-AMP phosphodiesterase 4D Q08499 PDE4D_HUMAN Homo sapiens 3 0.9038
VioE domain-containing protein Q7NSZ5 Q7NSZ5_CHRVO Chromobacterium violaceum 3 0.8924
VioE domain-containing protein Q7NSZ5 Q7NSZ5_CHRVO Chromobacterium violaceum 3 0.8924
Pyridoxal kinase O00764 PDXK_HUMAN Homo sapiens 3 0.8774
Pyridoxal kinase O00764 PDXK_HUMAN Homo sapiens 3 0.8774
Phospholipase A2 P00593 PA21B_BOVIN Bos taurus 3 0.8763
Phospholipase A2 P00593 PA21B_BOVIN Bos taurus 3 0.8763
Methylketone synthase I E0YCS2 E0YCS2_SOLHA Solanum habrochaites 3 0.8760
Methylketone synthase I E0YCS2 E0YCS2_SOLHA Solanum habrochaites 3 0.8760
Bromodomain adjacent to zinc finger domain protein 2B Q9UIF8 BAZ2B_HUMAN Homo sapiens 3 0.8712
Bromodomain adjacent to zinc finger domain protein 2B Q9UIF8 BAZ2B_HUMAN Homo sapiens 3 0.8712
Steroid Delta-isomerase P07445 SDIS_PSEPU Pseudomonas putida 2 0.8683
Steroid Delta-isomerase P07445 SDIS_PSEPU Pseudomonas putida 2 0.8683
Aldo-keto reductase family 1 member C3 P42330 AK1C3_HUMAN Homo sapiens 3 0.8627
Aldo-keto reductase family 1 member C3 P42330 AK1C3_HUMAN Homo sapiens 3 0.8627
Corticosteroid-binding globulin P08185 CBG_HUMAN Homo sapiens 3 0.8615
Corticosteroid-binding globulin P08185 CBG_HUMAN Homo sapiens 3 0.8615
ADP-ribosylation factor 1 P84077 ARF1_HUMAN Homo sapiens 2 0.8521
ADP-ribosylation factor 1 P84077 ARF1_HUMAN Homo sapiens 2 0.8521
Sulfotransferase 2A1 Q06520 ST2A1_HUMAN Homo sapiens 3 0.8501
Sulfotransferase 2A1 Q06520 ST2A1_HUMAN Homo sapiens 3 0.8501
Aldo-keto reductase family 1 member C2 P52895 AK1C2_HUMAN Homo sapiens 3 0.8421
Aldo-keto reductase family 1 member C2 P52895 AK1C2_HUMAN Homo sapiens 3 0.8421
Cytochrome P450 monooxygenase Q5YNS8 Q5YNS8_NOCFA Nocardia farcinica 3 0.8406
Cytochrome P450 monooxygenase Q5YNS8 Q5YNS8_NOCFA Nocardia farcinica 3 0.8406
Neocarzinostatin P0A3R9 NCZS_STRCZ Streptomyces carzinostaticus 3 0.8370
Neocarzinostatin P0A3R9 NCZS_STRCZ Streptomyces carzinostaticus 3 0.8370
Aromatase P11511 CP19A_HUMAN Homo sapiens 3 0.8280
Aromatase P11511 CP19A_HUMAN Homo sapiens 3 0.8280
Sulfotransferase 2B1 O00204 ST2B1_HUMAN Homo sapiens 2 0.8192
Sulfotransferase 2B1 O00204 ST2B1_HUMAN Homo sapiens 2 0.8192
Peptidyl-prolyl cis-trans isomerase FKBP5 Q13451 FKBP5_HUMAN Homo sapiens 3 0.8167
Peptidyl-prolyl cis-trans isomerase FKBP5 Q13451 FKBP5_HUMAN Homo sapiens 3 0.8167
Peptide deformylase 1B, chloroplastic/mitochondrial Q9FUZ2 DEF1B_ARATH Arabidopsis thaliana 3 0.8144
Peptide deformylase 1B, chloroplastic/mitochondrial Q9FUZ2 DEF1B_ARATH Arabidopsis thaliana 3 0.8144
3-ketosteroid dehydrogenase Q9RA02 Q9RA02_RHOER Rhodococcus erythropolis 2 0.8117
3-ketosteroid dehydrogenase Q9RA02 Q9RA02_RHOER Rhodococcus erythropolis 2 0.8117
2',3'-cyclic-nucleotide 3'-phosphodiesterase P16330 CN37_MOUSE Mus musculus 3 0.8101
2',3'-cyclic-nucleotide 3'-phosphodiesterase P16330 CN37_MOUSE Mus musculus 3 0.8101
Class B acid phosphatase Q540U1 APHA_SALTM Salmonella typhimurium 2 0.8055
Class B acid phosphatase Q540U1 APHA_SALTM Salmonella typhimurium 2 0.8055
Abscisic acid receptor PYL2 O80992 PYL2_ARATH Arabidopsis thaliana 3 0.8037
Abscisic acid receptor PYL2 O80992 PYL2_ARATH Arabidopsis thaliana 3 0.8037
17-beta-hydroxysteroid dehydrogenase type 1 P14061 DHB1_HUMAN Homo sapiens 2 0.7989
17-beta-hydroxysteroid dehydrogenase type 1 P14061 DHB1_HUMAN Homo sapiens 2 0.7989
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 P04191 AT2A1_RABIT Oryctolagus cuniculus 3 0.7975
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 P04191 AT2A1_RABIT Oryctolagus cuniculus 3 0.7975
Phospholipase A2, major isoenzyme P00592 PA21B_PIG Sus scrofa 3 0.7936
Phospholipase A2, major isoenzyme P00592 PA21B_PIG Sus scrofa 3 0.7936
Lactoylglutathione lyase Q9CPU0 LGUL_MOUSE Mus musculus 2 0.7935
Lactoylglutathione lyase Q9CPU0 LGUL_MOUSE Mus musculus 2 0.7935
Heat shock protein HSP 90-alpha P07900 HS90A_HUMAN Homo sapiens 2 0.7927
Heat shock protein HSP 90-alpha P07900 HS90A_HUMAN Homo sapiens 2 0.7927
Casein kinase II subunit alpha P68400 CSK21_HUMAN Homo sapiens 3 0.7926
Casein kinase II subunit alpha P68400 CSK21_HUMAN Homo sapiens 3 0.7926
17-beta-hydroxysteroid dehydrogenase 14 Q9BPX1 DHB14_HUMAN Homo sapiens 2 0.7914
17-beta-hydroxysteroid dehydrogenase 14 Q9BPX1 DHB14_HUMAN Homo sapiens 2 0.7914
Histone deacetylase 8 Q9BY41 HDAC8_HUMAN Homo sapiens 2 0.7909
Histone deacetylase 8 Q9BY41 HDAC8_HUMAN Homo sapiens 2 0.7909
Beta-secretase 1 P56817 BACE1_HUMAN Homo sapiens 2 0.7908
Beta-secretase 1 P56817 BACE1_HUMAN Homo sapiens 2 0.7908
Retinoic acid receptor RXR-alpha P19793 RXRA_HUMAN Homo sapiens 2 0.7906
Retinoic acid receptor RXR-alpha P19793 RXRA_HUMAN Homo sapiens 2 0.7906
Type IV / VI secretion system DotU domain-containing protein Q9KN50 Q9KN50_VIBCH Vibrio cholerae serotype O1 2 0.7901
Type IV / VI secretion system DotU domain-containing protein Q9KN50 Q9KN50_VIBCH Vibrio cholerae serotype O1 2 0.7901
Fatty acid-binding protein, adipocyte P15090 FABP4_HUMAN Homo sapiens 2 0.7879
Fatty acid-binding protein, adipocyte P15090 FABP4_HUMAN Homo sapiens 2 0.7879
Steroid Delta-isomerase P00947 SDIS_COMTE Comamonas testosteroni 2 0.7868
Steroid Delta-isomerase P00947 SDIS_COMTE Comamonas testosteroni 2 0.7868
Cytochrome P450 monooxygenase Q5YNS8 Q5YNS8_NOCFA Nocardia farcinica 3 0.7867
Cytochrome P450 monooxygenase Q5YNS8 Q5YNS8_NOCFA Nocardia farcinica 3 0.7867
GCN5-related N-acetyltransferase B1YEL6 B1YEL6_EXIS2 Exiguobacterium sibiricum 3 0.7832
GCN5-related N-acetyltransferase B1YEL6 B1YEL6_EXIS2 Exiguobacterium sibiricum 3 0.7832
Aldo-keto reductase family 1 member C1 Q04828 AK1C1_HUMAN Homo sapiens 2 0.7821
Aldo-keto reductase family 1 member C1 Q04828 AK1C1_HUMAN Homo sapiens 2 0.7821
Sulfide-quinone reductase B7JBP8 SQRD_ACIF2 Acidithiobacillus ferrooxidans) 2 0.7812
Sulfide-quinone reductase B7JBP8 SQRD_ACIF2 Acidithiobacillus ferrooxidans) 2 0.7812
Pheromone-binding protein ASP1 Q9U9J6 Q9U9J6_APIME Apis mellifera 2 0.7804
Pheromone-binding protein ASP1 Q9U9J6 Q9U9J6_APIME Apis mellifera 2 0.7804
Acetylcholinesterase P21836 ACES_MOUSE Mus musculus 2 0.7794
Acetylcholinesterase P21836 ACES_MOUSE Mus musculus 2 0.7794
GCN5-related N-acetyltransferase B1YEL6 B1YEL6_EXIS2 Exiguobacterium sibiricum 3 0.7793
GCN5-related N-acetyltransferase B1YEL6 B1YEL6_EXIS2 Exiguobacterium sibiricum 3 0.7793
Multidrug transporter MdfA P0AEY8 MDFA_ECOLI Escherichia coli 3 0.7789
Multidrug transporter MdfA P0AEY8 MDFA_ECOLI Escherichia coli 3 0.7789
Retinoic acid receptor RXR-alpha P19793 RXRA_HUMAN Homo sapiens 2 0.7787
Retinoic acid receptor RXR-alpha P19793 RXRA_HUMAN Homo sapiens 2 0.7787
Beta-secretase 1 P56817 BACE1_HUMAN Homo sapiens 2 0.7782
Beta-secretase 1 P56817 BACE1_HUMAN Homo sapiens 2 0.7782
CmeR Q7B8P6 Q7B8P6_CAMJU Campylobacter jejuni 2 0.7778
CmeR Q7B8P6 Q7B8P6_CAMJU Campylobacter jejuni 2 0.7778
Steroid Delta-isomerase P00947 SDIS_COMTE Comamonas testosteroni 3 0.7775
Steroid Delta-isomerase P00947 SDIS_COMTE Comamonas testosteroni 3 0.7775
Malate synthase G P9WK17 MASZ_MYCTU Mycobacterium tuberculosis 3 0.7768
Malate synthase G P9WK17 MASZ_MYCTU Mycobacterium tuberculosis 3 0.7768
Steroid Delta-isomerase P00947 SDIS_COMTE Comamonas testosteroni 2 0.7758
Steroid Delta-isomerase P00947 SDIS_COMTE Comamonas testosteroni 2 0.7758
Aldo-keto reductase family 1 member C2 P52895 AK1C2_HUMAN Homo sapiens 2 0.7748
Aldo-keto reductase family 1 member C2 P52895 AK1C2_HUMAN Homo sapiens 2 0.7748
Fatty acid-binding protein, liver P80226 FABPL_CHICK Gallus gallus 2 0.7717
Fatty acid-binding protein, liver P80226 FABPL_CHICK Gallus gallus 2 0.7717
Gastrotropin Q6IMW5 Q6IMW5_DANRE Danio rerio 2 0.7710
Gastrotropin Q6IMW5 Q6IMW5_DANRE Danio rerio 2 0.7710
ATP synthase subunit alpha, mitochondrial P19483 ATPA_BOVIN Bos taurus 3 0.7708
ATP synthase subunit alpha, mitochondrial P19483 ATPA_BOVIN Bos taurus 3 0.7708
Vitamin D3 dihydroxylase P18326 CPXE_STRGO Streptomyces griseolus 3 0.7692
Vitamin D3 dihydroxylase P18326 CPXE_STRGO Streptomyces griseolus 3 0.7692
Aldo-keto reductase family 1 member C2 P52895 AK1C2_HUMAN Homo sapiens 2 0.7685
Aldo-keto reductase family 1 member C2 P52895 AK1C2_HUMAN Homo sapiens 2 0.7685
Vitamin D3 dihydroxylase P18326 CPXE_STRGO Streptomyces griseolus 3 0.7683
Vitamin D3 dihydroxylase P18326 CPXE_STRGO Streptomyces griseolus 3 0.7683
Prostaglandin reductase 2 Q8N8N7 PTGR2_HUMAN Homo sapiens 2 0.7681
Prostaglandin reductase 2 Q8N8N7 PTGR2_HUMAN Homo sapiens 2 0.7681
CmeR Q7B8P6 Q7B8P6_CAMJU Campylobacter jejuni 2 0.7673
CmeR Q7B8P6 Q7B8P6_CAMJU Campylobacter jejuni 2 0.7673
Endoplasmin P14625 ENPL_HUMAN Homo sapiens 3 0.7668
Endoplasmin P14625 ENPL_HUMAN Homo sapiens 3 0.7668
Aldo-keto reductase family 1 member D1 P51857 AK1D1_HUMAN Homo sapiens 2 0.7646
Aldo-keto reductase family 1 member D1 P51857 AK1D1_HUMAN Homo sapiens 2 0.7646
17-beta-hydroxysteroid dehydrogenase type 1 P14061 DHB1_HUMAN Homo sapiens 2 0.7632
17-beta-hydroxysteroid dehydrogenase type 1 P14061 DHB1_HUMAN Homo sapiens 2 0.7632
Chitinase Q54276 Q54276_SERMA Serratia marcescens 2 0.7618
Chitinase Q54276 Q54276_SERMA Serratia marcescens 2 0.7618
Chitinase A Q9AMP1 Q9AMP1_VIBHA Vibrio harveyi 3 0.7599
Chitinase A Q9AMP1 Q9AMP1_VIBHA Vibrio harveyi 3 0.7599
Heat shock protein HSP 90-alpha P07900 HS90A_HUMAN Homo sapiens 2 0.7592
Heat shock protein HSP 90-alpha P07900 HS90A_HUMAN Homo sapiens 2 0.7592
Aldo-keto reductase family 1 member C3 P42330 AK1C3_HUMAN Homo sapiens 2 0.7592
Aldo-keto reductase family 1 member C3 P42330 AK1C3_HUMAN Homo sapiens 2 0.7592
Feruloyl esterase A O42807 FAEA_ASPNG Aspergillus niger 2 0.7581
Feruloyl esterase A O42807 FAEA_ASPNG Aspergillus niger 2 0.7581
Phospholipase A2, major isoenzyme P00592 PA21B_PIG Sus scrofa 3 0.7571
Phospholipase A2, major isoenzyme P00592 PA21B_PIG Sus scrofa 3 0.7571
Abscisic acid receptor PYL2 O80992 PYL2_ARATH Arabidopsis thaliana 3 0.7570
Abscisic acid receptor PYL2 O80992 PYL2_ARATH Arabidopsis thaliana 3 0.7570
Tetracycline repressor protein class D P0ACT4 TETR4_ECOLX Escherichia coli 2 0.7568
Tetracycline repressor protein class D P0ACT4 TETR4_ECOLX Escherichia coli 2 0.7568
Pheromone-binding protein ASP1 Q9U9J6 Q9U9J6_APIME Apis mellifera 2 0.7564
Pheromone-binding protein ASP1 Q9U9J6 Q9U9J6_APIME Apis mellifera 2 0.7564
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 P04191 AT2A1_RABIT Oryctolagus cuniculus 2 0.7562
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 P04191 AT2A1_RABIT Oryctolagus cuniculus 2 0.7562
Peptidyl-prolyl cis-trans isomerase FKBP1A P62942 FKB1A_HUMAN Homo sapiens 3 0.7555
Peptidyl-prolyl cis-trans isomerase FKBP1A P62942 FKB1A_HUMAN Homo sapiens 3 0.7555
Lipoprotein E P26093 HEL_HAEIN Haemophilus influenzae 3 0.7553
Lipoprotein E P26093 HEL_HAEIN Haemophilus influenzae 3 0.7553
Nuclear receptor ROR-gamma P51449 RORG_HUMAN Homo sapiens 2 0.7546
Nuclear receptor ROR-gamma P51449 RORG_HUMAN Homo sapiens 2 0.7546
cGMP-dependent 3',5'-cyclic phosphodiesterase O00408 PDE2A_HUMAN Homo sapiens 2 0.7541
cGMP-dependent 3',5'-cyclic phosphodiesterase O00408 PDE2A_HUMAN Homo sapiens 2 0.7541
Probable NDP-rhamnosyltransferase Q9ALM8 Q9ALM8_SACSN Saccharopolyspora spinosa 2 0.7539
Probable NDP-rhamnosyltransferase Q9ALM8 Q9ALM8_SACSN Saccharopolyspora spinosa 2 0.7539
Sex hormone-binding globulin P04278 SHBG_HUMAN Homo sapiens 3 0.7536
Sex hormone-binding globulin P04278 SHBG_HUMAN Homo sapiens 3 0.7536
High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A O76083 PDE9A_HUMAN Homo sapiens 2 0.7524
High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A O76083 PDE9A_HUMAN Homo sapiens 2 0.7524
Hydroxymethylglutaryl-CoA synthase Q9FD71 HMGCS_ENTFL Enterococcus faecalis 2 0.7514
Hydroxymethylglutaryl-CoA synthase Q9FD71 HMGCS_ENTFL Enterococcus faecalis 2 0.7514
Soluble cytochrome b562 P0ABE7 C562_ECOLX Escherichia coli 2 0.7503
Soluble cytochrome b562 P0ABE7 C562_ECOLX Escherichia coli 2 0.7503
Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial Q33862 Q33862_ASCSU Ascaris suum 3 0.7492
Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial Q33862 Q33862_ASCSU Ascaris suum 3 0.7492
Beta-1 adrenergic receptor P07700 ADRB1_MELGA Meleagris gallopavo 2 0.7490
Beta-1 adrenergic receptor P07700 ADRB1_MELGA Meleagris gallopavo 2 0.7490
Beta-1 adrenergic receptor P07700 ADRB1_MELGA Meleagris gallopavo 2 0.7485
Beta-1 adrenergic receptor P07700 ADRB1_MELGA Meleagris gallopavo 2 0.7485
Stromelysin-1 P08254 MMP3_HUMAN Homo sapiens 3 0.7483
Stromelysin-1 P08254 MMP3_HUMAN Homo sapiens 3 0.7483
Ferrochelatase, mitochondrial P22830 HEMH_HUMAN Homo sapiens 2 0.7480
11-beta-hydroxysteroid dehydrogenase 1 P28845 DHI1_HUMAN Homo sapiens 2 0.7480
11-beta-hydroxysteroid dehydrogenase 1 P28845 DHI1_HUMAN Homo sapiens 2 0.7480
Ferrochelatase, mitochondrial P22830 HEMH_HUMAN Homo sapiens 2 0.7480
NADPH-dependent oxidoreductase 2-alkenal reductase Q39172 AER_ARATH Arabidopsis thaliana 2 0.7473
NADPH-dependent oxidoreductase 2-alkenal reductase Q39172 AER_ARATH Arabidopsis thaliana 2 0.7473
Aldo-keto reductase family 1 member D1 P51857 AK1D1_HUMAN Homo sapiens 2 0.7471
Aldo-keto reductase family 1 member D1 P51857 AK1D1_HUMAN Homo sapiens 2 0.7471
Histone deacetylase 8 Q9BY41 HDAC8_HUMAN Homo sapiens 2 0.7470
Histone deacetylase 8 Q9BY41 HDAC8_HUMAN Homo sapiens 2 0.7470
Cytochrome P450 2A6 P11509 CP2A6_HUMAN Homo sapiens 3 0.7463
Cytochrome P450 2A6 P11509 CP2A6_HUMAN Homo sapiens 3 0.7463
Glucan 1,3-beta-glucosidase P29717 EXG1_CANAL Candida albicans 2 0.7449
Glucan 1,3-beta-glucosidase P29717 EXG1_CANAL Candida albicans 2 0.7449
Steroid C26-monooxygenase P9WPP1 CP125_MYCTU Mycobacterium tuberculosis 2 0.7435
Steroid C26-monooxygenase P9WPP1 CP125_MYCTU Mycobacterium tuberculosis 2 0.7435
Adenosylmethionine-8-amino-7-oxononanoate aminotransferase P12995 BIOA_ECOLI Escherichia coli 2 0.7431
Adenosylmethionine-8-amino-7-oxononanoate aminotransferase P12995 BIOA_ECOLI Escherichia coli 2 0.7431
ATP synthase subunit alpha, mitochondrial P19483 ATPA_BOVIN Bos taurus 3 0.7429
ATP synthase subunit alpha, mitochondrial P19483 ATPA_BOVIN Bos taurus 3 0.7429
High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A O76083 PDE9A_HUMAN Homo sapiens 2 0.7424
High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A O76083 PDE9A_HUMAN Homo sapiens 2 0.7424
Tryptophan synthase alpha chain P00929 TRPA_SALTY Salmonella typhimurium 3 0.7412
Tryptophan synthase alpha chain P00929 TRPA_SALTY Salmonella typhimurium 3 0.7412
ATP-dependent molecular chaperone HSP82 P02829 HSP82_YEAST Saccharomyces cerevisiae 2 0.7408
ATP-dependent molecular chaperone HSP82 P02829 HSP82_YEAST Saccharomyces cerevisiae 2 0.7408
Prothrombin P00734 THRB_HUMAN Homo sapiens 2 0.7397
Prothrombin P00734 THRB_HUMAN Homo sapiens 2 0.7397
ActVA 6 protein Q53908 Q53908_STRCH Streptomyces coelicolor 2 0.7396
ActVA 6 protein Q53908 Q53908_STRCH Streptomyces coelicolor 2 0.7396
Histone deacetylase 8 Q9BY41 HDAC8_HUMAN Homo sapiens 2 0.7383
Histone deacetylase 8 Q9BY41 HDAC8_HUMAN Homo sapiens 2 0.7383
ADP-ribosylation factor 1 P84080 ARF1_BOVIN Bos taurus 3 0.7379
ADP-ribosylation factor 1 P84080 ARF1_BOVIN Bos taurus 3 0.7379
Aldo-keto reductase family 1 member C2 P52895 AK1C2_HUMAN Homo sapiens 2 0.7379
Aldo-keto reductase family 1 member C2 P52895 AK1C2_HUMAN Homo sapiens 2 0.7379
Nucleoside diphosphate kinase Q5UQL3 NDK_MIMIV Acanthamoeba polyphaga mimivirus 2 0.7376
Nucleoside diphosphate kinase Q5UQL3 NDK_MIMIV Acanthamoeba polyphaga mimivirus 2 0.7376
Mitochondrial dynamics protein MIEF1 Q9NQG6 MID51_HUMAN Homo sapiens 2 0.7375
Mitochondrial dynamics protein MIEF1 Q9NQG6 MID51_HUMAN Homo sapiens 2 0.7375
5-formyltetrahydrofolate cyclo-ligase P75430 MTHFS_MYCPN Mycoplasma pneumoniae 2 0.7374
5-formyltetrahydrofolate cyclo-ligase P75430 MTHFS_MYCPN Mycoplasma pneumoniae 2 0.7374
Plasma membrane ATPase Q42932 Q42932_NICPL Nicotiana plumbaginifolia 2 0.7373
Plasma membrane ATPase Q42932 Q42932_NICPL Nicotiana plumbaginifolia 2 0.7373
Acetylcholinesterase P04058 ACES_TETCF Tetronarce californica 2 0.7367
Acetylcholinesterase P04058 ACES_TETCF Tetronarce californica 2 0.7367
Phenazine biosynthesis protein A/B Q396C9 Q396C9_BURL3 Burkholderia lata 2 0.7355
Phenazine biosynthesis protein A/B Q396C9 Q396C9_BURL3 Burkholderia lata 2 0.7355
Nuclear receptor subfamily 1 group I member 2 O75469 NR1I2_HUMAN Homo sapiens 3 0.7348
Nuclear receptor subfamily 1 group I member 2 O75469 NR1I2_HUMAN Homo sapiens 3 0.7348
Progesterone receptor P06401 PRGR_HUMAN Homo sapiens 2 0.7341
Progesterone receptor P06401 PRGR_HUMAN Homo sapiens 2 0.7341
4,4'-diapophytoene synthase A9JQL9 CRTM_STAAU Staphylococcus aureus 2 0.7340
4,4'-diapophytoene synthase A9JQL9 CRTM_STAAU Staphylococcus aureus 2 0.7340
Cellular retinoic acid-binding protein 2 P29373 RABP2_HUMAN Homo sapiens 2 0.7333
Cellular retinoic acid-binding protein 2 P29373 RABP2_HUMAN Homo sapiens 2 0.7333
Albumin P02768 ALBU_HUMAN Homo sapiens 2 0.7332
Albumin P02768 ALBU_HUMAN Homo sapiens 2 0.7332
2'-5'-oligoadenylate synthase 1 P00973 OAS1_HUMAN Homo sapiens 2 0.7320
2'-5'-oligoadenylate synthase 1 P00973 OAS1_HUMAN Homo sapiens 2 0.7320
Heat shock protein HSP 90-alpha P07900 HS90A_HUMAN Homo sapiens 2 0.7319
Heat shock protein HSP 90-alpha P07900 HS90A_HUMAN Homo sapiens 2 0.7319
Tryptophan synthase alpha chain P00929 TRPA_SALTY Salmonella typhimurium 2 0.7316
Tryptophan synthase alpha chain P00929 TRPA_SALTY Salmonella typhimurium 2 0.7316
Mineralocorticoid receptor P08235 MCR_HUMAN Homo sapiens 2 0.7314
Neocarzinostatin P0A3R9 NCZS_STRCZ Streptomyces carzinostaticus 2 0.7314
Mineralocorticoid receptor P08235 MCR_HUMAN Homo sapiens 2 0.7314
Neocarzinostatin P0A3R9 NCZS_STRCZ Streptomyces carzinostaticus 2 0.7314
cGMP-dependent protein kinase 2 Q13237 KGP2_HUMAN Homo sapiens 2 0.7313
cGMP-dependent protein kinase 2 Q13237 KGP2_HUMAN Homo sapiens 2 0.7313
CCA-adding enzyme O28126 CCA_ARCFU Archaeoglobus fulgidus 2 0.7298
CCA-adding enzyme O28126 CCA_ARCFU Archaeoglobus fulgidus 2 0.7298
Acetylcholinesterase P04058 ACES_TETCF Tetronarce californica 3 0.7294
Acetylcholinesterase P04058 ACES_TETCF Tetronarce californica 3 0.7294
Alpha-aminoadipic semialdehyde dehydrogenase P49419 AL7A1_HUMAN Homo sapiens 2 0.7288
Alpha-aminoadipic semialdehyde dehydrogenase P49419 AL7A1_HUMAN Homo sapiens 2 0.7288
Polyunsaturated fatty acid lipoxygenase ALOX15 P12530 LOX15_RABIT Oryctolagus cuniculus 2 0.7287
Polyunsaturated fatty acid lipoxygenase ALOX15 P12530 LOX15_RABIT Oryctolagus cuniculus 2 0.7287
histidine kinase O32393 O32393_ARTPT Arthrospira platensis 2 0.7282
Glutamate receptor 2 P19491 GRIA2_RAT Rattus norvegicus 2 0.7282
histidine kinase O32393 O32393_ARTPT Arthrospira platensis 2 0.7282
Glutamate receptor 2 P19491 GRIA2_RAT Rattus norvegicus 2 0.7282
Thermolysin P00800 THER_BACTH Bacillus thermoproteolyticus 2 0.7276
Aldo-keto reductase family 1 member D1 P51857 AK1D1_HUMAN Homo sapiens 2 0.7276
Aldo-keto reductase family 1 member D1 P51857 AK1D1_HUMAN Homo sapiens 2 0.7276
Thermolysin P00800 THER_BACTH Bacillus thermoproteolyticus 2 0.7276
Endothiapepsin P11838 CARP_CRYPA Cryphonectria parasitica 2 0.7273
Caffeic acid 3-O-methyltransferase P28002 COMT1_MEDSA Medicago sativa 2 0.7273
Endothiapepsin P11838 CARP_CRYPA Cryphonectria parasitica 2 0.7273
Caffeic acid 3-O-methyltransferase P28002 COMT1_MEDSA Medicago sativa 2 0.7273
17-beta-hydroxysteroid dehydrogenase type 1 P14061 DHB1_HUMAN Homo sapiens 2 0.7268
17-beta-hydroxysteroid dehydrogenase type 1 P14061 DHB1_HUMAN Homo sapiens 2 0.7268
Abscisic acid receptor PYL3 Q9SSM7 PYL3_ARATH Arabidopsis thaliana 3 0.7264
Abscisic acid receptor PYL3 Q9SSM7 PYL3_ARATH Arabidopsis thaliana 3 0.7264
UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--LD-lysine ligase Q9WY79 MURE_THEMA Thermotoga maritima 3 0.7262
UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--LD-lysine ligase Q9WY79 MURE_THEMA Thermotoga maritima 3 0.7262
Progesterone receptor P06401 PRGR_HUMAN Homo sapiens 2 0.7259
Progesterone receptor P06401 PRGR_HUMAN Homo sapiens 2 0.7259
Rhodopsin kinase GRK1 P28327 GRK1_BOVIN Bos taurus 2 0.7258
Rhodopsin kinase GRK1 P28327 GRK1_BOVIN Bos taurus 2 0.7258
Heat shock protein HSP 90-alpha P07900 HS90A_HUMAN Homo sapiens 2 0.7256
Heat shock protein HSP 90-alpha P07900 HS90A_HUMAN Homo sapiens 2 0.7256
Fibroblast growth factor receptor 1 P11362 FGFR1_HUMAN Homo sapiens 3 0.7250
Streptavidin P22629 SAV_STRAV Streptomyces avidinii 2 0.7250
Streptavidin P22629 SAV_STRAV Streptomyces avidinii 2 0.7250
Fibroblast growth factor receptor 1 P11362 FGFR1_HUMAN Homo sapiens 3 0.7250
Chalcone synthase 2 P30074 CHS2_MEDSA Medicago sativa 2 0.7248
Chalcone synthase 2 P30074 CHS2_MEDSA Medicago sativa 2 0.7248
Nitric oxide synthase, inducible P29477 NOS2_MOUSE Mus musculus 2 0.7246
Nitric oxide synthase, inducible P29477 NOS2_MOUSE Mus musculus 2 0.7246
11-beta-hydroxysteroid dehydrogenase 1 P50172 DHI1_MOUSE Mus musculus 2 0.7245
11-beta-hydroxysteroid dehydrogenase 1 P50172 DHI1_MOUSE Mus musculus 2 0.7245
Basic phospholipase A2 VRV-PL-VIIIa P59071 PA2B8_DABRR Daboia russelii 2 0.7244
Sulfotransferase 2A1 Q06520 ST2A1_HUMAN Homo sapiens 3 0.7244
Basic phospholipase A2 VRV-PL-VIIIa P59071 PA2B8_DABRR Daboia russelii 2 0.7244
Sulfotransferase 2A1 Q06520 ST2A1_HUMAN Homo sapiens 3 0.7244
Adenylate cyclase type 5 P30803 ADCY5_CANLF Canis lupus familiaris 3 0.7242
Adenylate cyclase type 5 P30803 ADCY5_CANLF Canis lupus familiaris 3 0.7242
Carbonic anhydrase 1 P00915 CAH1_HUMAN Homo sapiens 2 0.7237
3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase P19992 HSD_STREX Streptomyces exfoliatus 2 0.7237
Carbonic anhydrase 1 P00915 CAH1_HUMAN Homo sapiens 2 0.7237
3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase P19992 HSD_STREX Streptomyces exfoliatus 2 0.7237
M17 leucyl aminopeptidase Q8IL11 Q8IL11_PLAF7 Plasmodium falciparum 2 0.7236
M17 leucyl aminopeptidase Q8IL11 Q8IL11_PLAF7 Plasmodium falciparum 2 0.7236
HTH-type transcriptional regulator EthR P9WMC1 ETHR_MYCTU Mycobacterium tuberculosis 3 0.7232
HTH-type transcriptional regulator EthR P9WMC1 ETHR_MYCTU Mycobacterium tuberculosis 3 0.7232
Abscisic acid receptor PYL9 Q84MC7 PYL9_ARATH Arabidopsis thaliana 3 0.7230
Abscisic acid receptor PYL9 Q84MC7 PYL9_ARATH Arabidopsis thaliana 3 0.7230
Nitrogen regulatory protein P-II O66513 GLNB_AQUAE Aquifex aeolicus 2 0.7223
Nitrogen regulatory protein P-II O66513 GLNB_AQUAE Aquifex aeolicus 2 0.7223
Purine nucleoside phosphorylase P00491 PNPH_HUMAN Homo sapiens 2 0.7210
Purine nucleoside phosphorylase P00491 PNPH_HUMAN Homo sapiens 2 0.7210
Mitogen-activated protein kinase 14 Q16539 MK14_HUMAN Homo sapiens 2 0.7204
Mitogen-activated protein kinase 14 Q16539 MK14_HUMAN Homo sapiens 2 0.7204
Methionine aminopeptidase 1 P53582 MAP11_HUMAN Homo sapiens 2 0.7204
Methionine aminopeptidase 1 P53582 MAP11_HUMAN Homo sapiens 2 0.7204
Gastrotropin P51161 FABP6_HUMAN Homo sapiens 2 0.7198
Gastrotropin P51161 FABP6_HUMAN Homo sapiens 2 0.7198
Streptavidin P22629 SAV_STRAV Streptomyces avidinii 2 0.7195
Streptavidin P22629 SAV_STRAV Streptomyces avidinii 2 0.7195
Steroid Delta-isomerase P07445 SDIS_PSEPU Pseudomonas putida 2 0.7189
Steroid Delta-isomerase P07445 SDIS_PSEPU Pseudomonas putida 2 0.7189
Solanesyl diphosphate synthase 3, chloroplastic/mitochondrial Q5HZ00 SPS3_ARATH Arabidopsis thaliana 2 0.7188
Solanesyl diphosphate synthase 3, chloroplastic/mitochondrial Q5HZ00 SPS3_ARATH Arabidopsis thaliana 2 0.7188
Inosine-5'-monophosphate dehydrogenase P50097 IMDH_TRIFO Tritrichomonas foetus 2 0.7187
Inosine-5'-monophosphate dehydrogenase P50097 IMDH_TRIFO Tritrichomonas foetus 2 0.7187
Tyrosyl-DNA phosphodiesterase 2 Q9JJX7 TYDP2_MOUSE Mus musculus 2 0.7182
Tyrosyl-DNA phosphodiesterase 2 Q9JJX7 TYDP2_MOUSE Mus musculus 2 0.7182
Single-stranded-DNA-specific exonuclease RecJ D0EM60 D0EM60_DEIRD Deinococcus radiodurans 2 0.7177
Single-stranded-DNA-specific exonuclease RecJ D0EM60 D0EM60_DEIRD Deinococcus radiodurans 2 0.7177
Disintegrin and metalloproteinase domain-containing protein 17 P78536 ADA17_HUMAN Homo sapiens 2 0.7176
Disintegrin and metalloproteinase domain-containing protein 17 P78536 ADA17_HUMAN Homo sapiens 2 0.7176
Adenylate cyclase 2 A0A2U2H3Y1 A0A384LKY8_YERPE Yersinia pestis 2 0.7173
Adenylate cyclase 2 A0A2U2H3Y1 A0A384LKY8_YERPE Yersinia pestis 2 0.7173
Adenylate cyclase type 5 P30803 ADCY5_CANLF Canis lupus familiaris 3 0.7172
Adenylate cyclase type 5 P30803 ADCY5_CANLF Canis lupus familiaris 3 0.7172
MutT/nudix family protein Q5SJY9 Q5SJY9_THET8 Thermus thermophilus 2 0.7171
MutT/nudix family protein Q5SJY9 Q5SJY9_THET8 Thermus thermophilus 2 0.7171
Retinol dehydratase Q26490 Q26490_SPOFR Spodoptera frugiperda 3 0.7170
Retinol dehydratase Q26490 Q26490_SPOFR Spodoptera frugiperda 3 0.7170
Fatty acid-binding protein 10-A, liver basic Q9I8L5 FA10A_DANRE Danio rerio 2 0.7169
Fatty acid-binding protein 10-A, liver basic Q9I8L5 FA10A_DANRE Danio rerio 2 0.7169
Muconolactone Delta-isomerase Q8G9L0 Q8G9L0_RHOOP Rhodococcus opacus 2 0.7166
Muconolactone Delta-isomerase Q8G9L0 Q8G9L0_RHOOP Rhodococcus opacus 2 0.7166
Carbonic anhydrase 4 Q64444 CAH4_MOUSE Mus musculus 2 0.7165
Carbonic anhydrase 4 Q64444 CAH4_MOUSE Mus musculus 2 0.7165
Prothrombin P00734 THRB_HUMAN Homo sapiens 2 0.7160
Prothrombin P00734 THRB_HUMAN Homo sapiens 2 0.7160
NAD-capped RNA hydrolase NudC P32664 NUDC_ECOLI Escherichia coli 2 0.7157
NAD-capped RNA hydrolase NudC P32664 NUDC_ECOLI Escherichia coli 2 0.7157
Abscisic acid receptor PYR1 O49686 PYR1_ARATH Arabidopsis thaliana 3 0.7152
Pheromone-binding protein ASP1 Q9U9J6 Q9U9J6_APIME Apis mellifera 2 0.7152
Pheromone-binding protein ASP1 Q9U9J6 Q9U9J6_APIME Apis mellifera 2 0.7152
Abscisic acid receptor PYR1 O49686 PYR1_ARATH Arabidopsis thaliana 3 0.7152
Anhydro-N-acetylmuramic acid kinase Q9I5Q5 ANMK_PSEAE Pseudomonas aeruginosa 2 0.7148
Anhydro-N-acetylmuramic acid kinase Q9I5Q5 ANMK_PSEAE Pseudomonas aeruginosa 2 0.7148
Diamine acetyltransferase 1 P21673 SAT1_HUMAN Homo sapiens 2 0.7145
Diamine acetyltransferase 1 P21673 SAT1_HUMAN Homo sapiens 2 0.7145
Ferrochelatase, mitochondrial P22830 HEMH_HUMAN Homo sapiens 2 0.7144
Sex hormone-binding globulin P04278 SHBG_HUMAN Homo sapiens 2 0.7144
Ferrochelatase, mitochondrial P22830 HEMH_HUMAN Homo sapiens 2 0.7144
Sex hormone-binding globulin P04278 SHBG_HUMAN Homo sapiens 2 0.7144
Fatty acid-binding protein, liver P80226 FABPL_CHICK Gallus gallus 2 0.7139
Fatty acid-binding protein, liver P80226 FABPL_CHICK Gallus gallus 2 0.7139
3'-5' exoribonuclease Rv2179c P9WJ73 EXRBN_MYCTU Mycobacterium tuberculosis 2 0.7137
3'-5' exoribonuclease Rv2179c P9WJ73 EXRBN_MYCTU Mycobacterium tuberculosis 2 0.7137
Acidic phospholipase A2 3 P60045 PA2A3_NAJSG Naja sagittifera 2 0.7133
Acidic phospholipase A2 3 P60045 PA2A3_NAJSG Naja sagittifera 2 0.7133
17-beta-hydroxysteroid dehydrogenase type 1 P14061 DHB1_HUMAN Homo sapiens 2 0.7111
17-beta-hydroxysteroid dehydrogenase type 1 P14061 DHB1_HUMAN Homo sapiens 2 0.7111
ATP synthase subunit alpha, mitochondrial P19483 ATPA_BOVIN Bos taurus 2 0.7106
ATP synthase subunit alpha, mitochondrial P19483 ATPA_BOVIN Bos taurus 2 0.7106
Endoplasmin P41148 ENPL_CANLF Canis lupus familiaris 2 0.7105
Endoplasmin P41148 ENPL_CANLF Canis lupus familiaris 2 0.7105
Cyclic GMP-AMP phosphodiesterase SMPDL3A Q92484 ASM3A_HUMAN Homo sapiens 2 0.7104
Cyclic GMP-AMP phosphodiesterase SMPDL3A Q92484 ASM3A_HUMAN Homo sapiens 2 0.7104
Protein mono-ADP-ribosyltransferase PARP14 Q460N5 PAR14_HUMAN Homo sapiens 2 0.7102
Protein mono-ADP-ribosyltransferase PARP14 Q460N5 PAR14_HUMAN Homo sapiens 2 0.7102
Tyrosine-protein kinase JAK2 O60674 JAK2_HUMAN Homo sapiens 2 0.7101
Tyrosine-protein kinase JAK2 O60674 JAK2_HUMAN Homo sapiens 2 0.7101
Protein UshA P07024 USHA_ECOLI Escherichia coli 2 0.7100
Protein UshA P07024 USHA_ECOLI Escherichia coli 2 0.7100
Gamma-aminobutyric acid type B receptor subunit 1 Q9UBS5 GABR1_HUMAN Homo sapiens 2 0.7099
Gamma-aminobutyric acid type B receptor subunit 1 Q9UBS5 GABR1_HUMAN Homo sapiens 2 0.7099
Liver carboxylesterase 1 P23141 EST1_HUMAN Homo sapiens 2 0.7096
Liver carboxylesterase 1 P23141 EST1_HUMAN Homo sapiens 2 0.7096
5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase 1 O50008 METE1_ARATH Arabidopsis thaliana 2 0.7095
5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase 1 O50008 METE1_ARATH Arabidopsis thaliana 2 0.7095
Aspartate aminotransferase, mitochondrial P00508 AATM_CHICK Gallus gallus 2 0.7088
Aspartate aminotransferase, mitochondrial P00508 AATM_CHICK Gallus gallus 2 0.7088
Pantothenate synthetase P9WIL4 PANC_MYCTO Mycobacterium tuberculosis 2 0.7087
Pantothenate synthetase P9WIL4 PANC_MYCTO Mycobacterium tuberculosis 2 0.7087
Farnesyl pyrophosphate synthase Q86C09 Q86C09_9TRYP Trypanosoma brucei 2 0.7086
Farnesyl pyrophosphate synthase Q86C09 Q86C09_9TRYP Trypanosoma brucei 2 0.7086
Flavin-dependent monooxygenase Q93L51 TETX_BACT4 Bacteroides thetaiotaomicron 2 0.7085
Flavin-dependent monooxygenase Q93L51 TETX_BACT4 Bacteroides thetaiotaomicron 2 0.7085
Abscisic acid receptor PYR1 O49686 PYR1_ARATH Arabidopsis thaliana 3 0.7083
Abscisic acid receptor PYR1 O49686 PYR1_ARATH Arabidopsis thaliana 3 0.7083
Putative sugar kinase PH1459 O59128 Y1459_PYRHO Pyrococcus horikoshii 2 0.7081
Putative sugar kinase PH1459 O59128 Y1459_PYRHO Pyrococcus horikoshii 2 0.7081
Tryptophan synthase alpha chain P00929 TRPA_SALTY Salmonella typhimurium 3 0.7074
Tryptophan synthase alpha chain P00929 TRPA_SALTY Salmonella typhimurium 3 0.7074
Alpha/beta hydrolase fold protein D2J2T6 D2J2T6_9RHIZ Ochrobactrum sp. T63 2 0.7071
Alpha/beta hydrolase fold protein D2J2T6 D2J2T6_9RHIZ Ochrobactrum sp. T63 2 0.7071
Nitric oxide synthase, inducible P35228 NOS2_HUMAN Homo sapiens 2 0.7067
Nitric oxide synthase, inducible P35228 NOS2_HUMAN Homo sapiens 2 0.7067
1-deoxy-D-xylulose 5-phosphate reductoisomerase P45568 DXR_ECOLI Escherichia coli 2 0.7066
1-deoxy-D-xylulose 5-phosphate reductoisomerase P45568 DXR_ECOLI Escherichia coli 2 0.7066
Aldo-keto reductase family 1 member C2 P52895 AK1C2_HUMAN Homo sapiens 2 0.7062
Aldo-keto reductase family 1 member C2 P52895 AK1C2_HUMAN Homo sapiens 2 0.7062
N-terminal acetyltransferase A complex subunit NAT1 P12945 NAT1_YEAST Saccharomyces cerevisiae 2 0.7058
Lactoylglutathione lyase Q04760 LGUL_HUMAN Homo sapiens 2 0.7058
N-terminal acetyltransferase A complex subunit NAT1 P12945 NAT1_YEAST Saccharomyces cerevisiae 2 0.7058
Lactoylglutathione lyase Q04760 LGUL_HUMAN Homo sapiens 2 0.7058
Heat shock protein HSP 90-alpha P07900 HS90A_HUMAN Homo sapiens 2 0.7054
4-diphosphocytidyl-2-C-methyl-D-erythritol kinase O67060 ISPE_AQUAE Aquifex aeolicus 2 0.7054
Heat shock protein HSP 90-alpha P07900 HS90A_HUMAN Homo sapiens 2 0.7054
4-diphosphocytidyl-2-C-methyl-D-erythritol kinase O67060 ISPE_AQUAE Aquifex aeolicus 2 0.7054
Glutamate receptor ionotropic, kainate 1 P22756 GRIK1_RAT Rattus norvegicus 2 0.7051
Glutamate receptor ionotropic, kainate 1 P22756 GRIK1_RAT Rattus norvegicus 2 0.7051
ADP-ribosyl-[dinitrogen reductase] hydrolase A7XNI2 A7XNI2_AZOBR Azospirillum brasilense 2 0.7049
ADP-ribosyl-[dinitrogen reductase] hydrolase A7XNI2 A7XNI2_AZOBR Azospirillum brasilense 2 0.7049
L-lactate dehydrogenase A chain P13491 LDHA_RABIT Oryctolagus cuniculus 2 0.7047
L-lactate dehydrogenase A chain P13491 LDHA_RABIT Oryctolagus cuniculus 2 0.7047
Endothiapepsin P11838 CARP_CRYPA Cryphonectria parasitica 2 0.7047
Endothiapepsin P11838 CARP_CRYPA Cryphonectria parasitica 2 0.7047
mRNA cleavage and polyadenylation factor CLP1 Q08685 CLP1_YEAST Saccharomyces cerevisiae 2 0.7046
mRNA cleavage and polyadenylation factor CLP1 Q08685 CLP1_YEAST Saccharomyces cerevisiae 2 0.7046
Chloramphenicol acetyltransferase P62577 CAT_ECOLX Escherichia coli 2 0.7042
Chloramphenicol acetyltransferase P62577 CAT_ECOLX Escherichia coli 2 0.7042
Glutamate receptor 2 P19491 GRIA2_RAT Rattus norvegicus 2 0.7041
Purine nucleoside phosphorylase DeoD-type Q5EEL8 DEOD_BACCE Bacillus cereus 2 0.7041
Glutamate receptor 2 P19491 GRIA2_RAT Rattus norvegicus 2 0.7041
Purine nucleoside phosphorylase DeoD-type Q5EEL8 DEOD_BACCE Bacillus cereus 2 0.7041
2',3'-cyclic-nucleotide 3'-phosphodiesterase P16330 CN37_MOUSE Mus musculus 2 0.7039
2',3'-cyclic-nucleotide 3'-phosphodiesterase P16330 CN37_MOUSE Mus musculus 2 0.7039
Cytochrome P450 monooxygenase Q5YNS8 Q5YNS8_NOCFA Nocardia farcinica 2 0.7037
Cytochrome P450 monooxygenase Q5YNS8 Q5YNS8_NOCFA Nocardia farcinica 2 0.7037
L-methionine gamma-lyase Q84AR1 Q84AR1_CITFR Citrobacter freundii 3 0.7033
L-methionine gamma-lyase Q84AR1 Q84AR1_CITFR Citrobacter freundii 3 0.7033
CCA-adding enzyme O28126 CCA_ARCFU Archaeoglobus fulgidus 2 0.7031
CCA-adding enzyme O28126 CCA_ARCFU Archaeoglobus fulgidus 2 0.7031
2',3'-cyclic-nucleotide 3'-phosphodiesterase P16330 CN37_MOUSE Mus musculus 2 0.7022
2',3'-cyclic-nucleotide 3'-phosphodiesterase P16330 CN37_MOUSE Mus musculus 2 0.7022
Streptavidin P22629 SAV_STRAV Streptomyces avidinii 2 0.7022
Streptavidin P22629 SAV_STRAV Streptomyces avidinii 2 0.7022
Endoplasmin P41148 ENPL_CANLF Canis lupus familiaris 2 0.7015
Putative fructokinase O05510 SCRK_BACSU Bacillus subtilis 2 0.7015
Endoplasmin P41148 ENPL_CANLF Canis lupus familiaris 2 0.7015
Putative fructokinase O05510 SCRK_BACSU Bacillus subtilis 2 0.7015
Camphor 5-monooxygenase P00183 CPXA_PSEPU Pseudomonas putida 3 0.7013
Camphor 5-monooxygenase P00183 CPXA_PSEPU Pseudomonas putida 3 0.7013
Steroid 17-alpha-hydroxylase/17,20 lyase P05093 CP17A_HUMAN Homo sapiens 2 0.7010
Steroid 17-alpha-hydroxylase/17,20 lyase P05093 CP17A_HUMAN Homo sapiens 2 0.7010
Aldo-keto reductase family 1 member B1 P15121 ALDR_HUMAN Homo sapiens 2 0.7008
Aldo-keto reductase family 1 member B1 P15121 ALDR_HUMAN Homo sapiens 2 0.7008
Estrogen receptor P03372 ESR1_HUMAN Homo sapiens 2 0.7005
Estrogen receptor P03372 ESR1_HUMAN Homo sapiens 2 0.7005
Ribosyldihydronicotinamide dehydrogenase [quinone] P16083 NQO2_HUMAN Homo sapiens 2 0.7004
Tetracycline repressor protein class H P51561 TETR8_PASMD Pasteurella multocida 2 0.7004
Tetracycline repressor protein class H P51561 TETR8_PASMD Pasteurella multocida 2 0.7004
Ribosyldihydronicotinamide dehydrogenase [quinone] P16083 NQO2_HUMAN Homo sapiens 2 0.7004
11-beta-hydroxysteroid dehydrogenase 1 P28845 DHI1_HUMAN Homo sapiens 2 0.7000
Alanine racemase Q180W0 Q180W0_CLOD6 Clostridioides difficile 2 0.7000
Alanine racemase Q180W0 Q180W0_CLOD6 Clostridioides difficile 2 0.7000
11-beta-hydroxysteroid dehydrogenase 1 P28845 DHI1_HUMAN Homo sapiens 2 0.7000

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