2-(4-hydroxyphenyl)ethyl triacontanoate - Compound Card

2-(4-hydroxyphenyl)ethyl triacontanoate

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2-(4-hydroxyphenyl)ethyl triacontanoate

Structure
Zoomed Structure
  • Family: Bignoniaceae
  • Kingdom: Plantae
  • Class: Fatty Acid
Canonical Smiles CCCCCCCCCCCCCCCCCCCCCCCCCCCCCC(=O)OCCc1ccc(cc1)O
InChI InChI=1S/C38H68O3/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-21-22-23-24-25-26-27-28-29-38(40)41-35-34-36-30-32-37(39)33-31-36/h30-33,39H,2-29,34-35H2,1H3
InChIKey GBROUZOGGIPVJM-UHFFFAOYSA-N
Formula C38H68O3
HBA 3
HBD 1
MW 572.96
Rotatable Bonds 31
TPSA 46.53
LogP 12.42
Number Rings 1
Number Aromatic Rings 1
Heavy Atom Count 41
Formal Charge 0
Fraction CSP3 0.82
Exact Mass 572.52
Number of Lipinski Rule Violations 2
# Species Family Kingdom NCBI Taxonomy ID
1 Newbouldia laevis Bignoniaceae Plantae 211924

Showing of synonyms

  • Eyong KO, Folefoc GN, et al. (2006). Newbouldiaquinone A: A naphthoquinone-anthraquinone ether coupled pigment, as a potential antimicrobial and antimalarial agent from Newbouldia laevis.. Phytochemistry,2006, 67(6), 605-609. [View] [PubMed]
Pubchem: 10008272
Nmrshiftdb2: 70043517

No compound-protein relationship available.

Structure

SMILES: c1ccccc1

Level: 0

Mol. Weight: 78.11 g/mol

No bioactivities available.

Absorption

Caco-2 (logPapp)
-4.99
Human Oral Bioavailability 20%
Non-Bioavailable
Human Intestinal Absorption
Absorbed
Madin-Darby Canine Kidney
-3.96
Human Oral Bioavailability 50%
Non-Bioavailable
P-Glycoprotein Inhibitor
Non-Inhibitor
P-Glycoprotein Substrate
Substrate
Skin Permeability
-0.91

Distribution

Blood-Brain Barrier (CNS)
-
Blood-Brain Barrier
Penetrable
Fraction Unbound (Human)
2.37
Plasma Protein Binding
57.79
Steady State Volume of Distribution
-

Metabolism

Breast Cancer Resistance Protein
Inhibitor
CYP 1A2 Inhibitor
Non-Inhibitor
CYP 1A2 Substrate
Non-Substrate
CYP 2C19 Inhibitor
Non-Inhibitor
CYP 2C19 Substrate
Non-Substrate
CYP 2C9 Inhibitor
Non-Inhibitor
CYP 2C9 Substrate
Non-Substrate
CYP 2D6 Inhibitor
Non-Inhibitor
CYP 2D6 Substrate
Non-Substrate
CYP 3A4 Inhibitor
Inhibitor
CYP 3A4 Substrate
Non-Substrate
OATP1B1
Non-Inhibitor
OATP1B3
Non-Inhibitor

Excretion

Clearance
4.31
Organic Cation Transporter 2
Non-Inhibitor
Half-Life of Drug
-

Toxicity

AMES Mutagenesis
Safe
Avian
Safe
Bee
Safe
Bioconcentration Factor
1.38
Biodegradation
Toxic
Carcinogenesis
Safe
Crustacean
Toxic
Liver Injury I (DILI)
Toxic
Eye Corrosion
Safe
Eye Irritation
Toxic
Maximum Tolerated Dose
1.29
Liver Injury II
Safe
hERG Blockers
Toxic
Daphnia Maga
5.35
Micronucleos
Safe
NR-AhR
Safe
NR-AR
Safe
NR-AR-LBD
Safe
NR-Aromatase
Safe
NR-ER
Toxic
NR-ER-LBD
Safe
NR-GR
Safe
NR-PPAR-gamma
Safe
NR-TR
Toxic
T. Pyriformis
-4945.35
Rat (Acute)
1.95
Rat (Chronic Oral)
2.84
Fathead Minnow
16.84
Respiratory Disease
Safe
Skin Sensitisation
Toxic
SR-ARE
Safe
SR-ATAD5
Safe
SR-HSE
Safe
SR-MMP
Safe
SR-p53
Safe

General Properties

Boiling Point
380.48
Hydration Free Energy
-2.9
Log(D) at pH=7.4
8.54
Log(P)
15.74
Log S
-7.2
Log(Vapor Pressure)
-10.83
Melting Point
78.8
pKa Acid
11.94
pKa Basic
5.79
Protein Name UniProt ID Entry Name Species #Pharmacophore Points Probability (0.7 ≤ Tversky Score ≤ 1.0)
Heat shock protein HSP 90-alpha P07900 HS90A_HUMAN Homo sapiens 3 0.9759
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A Q9Y233 PDE10_HUMAN Homo sapiens 3 0.9653
DNA gyrase subunit A P0AES5 GYRA_SHIFL Shigella flexneri 3 0.9600
Threonine synthase 1, chloroplastic Q9S7B5 THRC1_ARATH Arabidopsis thaliana 3 0.9600
Pantothenate synthetase P9WIL5 PANC_MYCTU Mycobacterium tuberculosis 3 0.9530
D-aminoacyl-tRNA deacylase Q8IIS0 DTD_PLAF7 Plasmodium falciparum 3 0.9348
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform P48736 PK3CG_HUMAN Homo sapiens 3 0.9337
Glycogen synthase kinase-3 beta P49841 GSK3B_HUMAN Homo sapiens 3 0.9335
Valacyclovir hydrolase Q86WA6 BPHL_HUMAN Homo sapiens 3 0.9334
Heat shock protein HSP 90-alpha P07900 HS90A_HUMAN Homo sapiens 3 0.9260
NADPH dehydrogenase 1 Q02899 OYE1_SACPS Saccharomyces pastorianus 3 0.9228
S-methyl-5'-thioadenosine phosphorylase I0B503 I0B503_SCHMA Schistosoma mansoni 3 0.9177
2-phospho-L-lactate transferase Q8PVT6 COFD_METMA Methanosarcina mazei 3 0.9076
Heat shock protein HSP 90-alpha P07900 HS90A_HUMAN Homo sapiens 3 0.9060
Mycocyclosin synthase P9WPP7 CP121_MYCTU Mycobacterium tuberculosis 3 0.9053
Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase Q9TQS6 DHDH_MACFA Macaca fascicularis 3 0.9022
Sulfotransferase 1A1 P50225 ST1A1_HUMAN Homo sapiens 3 0.8996
NAD-capped RNA hydrolase NudC P32664 NUDC_ECOLI Escherichia coli 3 0.8992
Beta-1 adrenergic receptor P07700 ADRB1_MELGA Meleagris gallopavo 3 0.8919
Gag-Pol polyprotein P03367 POL_HV1BR Human immunodeficiency virus type 1 group M subtype B 3 0.8886
HTH-type transcriptional repressor PurR P0ACP7 PURR_ECOLI Escherichia coli 3 0.8831
ADP-ribosylation factor 1 P84077 ARF1_HUMAN Homo sapiens 2 0.8793
HTH-type transcriptional repressor PurR P0ACP7 PURR_ECOLI Escherichia coli 3 0.8748
DNA polymerase III subunit epsilon P03007 DPO3E_ECOLI Escherichia coli 3 0.8684
Queuine tRNA-ribosyltransferase P28720 TGT_ZYMMO Zymomonas mobilis subsp. mobilis 3 0.8676
Queuine tRNA-ribosyltransferase P28720 TGT_ZYMMO Zymomonas mobilis subsp. mobilis 3 0.8614
5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase Q81LL4 MTNN_BACAN Bacillus anthracis 3 0.8586
S-norcoclaurine synthase Q67A25 NCS_THLFG Thalictrum flavum subsp. glaucum 3 0.8567
Soluble cytochrome b562 P0ABE7 C562_ECOLX Escherichia coli 3 0.8552
Prenyltransferase Q4R2T2 Q4R2T2_STRC1 Streptomyces sp 3 0.8541
S-methyl-5'-thioadenosine phosphorylase Q97W94 MTAP_SACS2 Saccharolobus solfataricus 3 0.8527
NADPH-dependent 7-cyano-7-deazaguanine reductase Q9KTK0 QUEF_VIBCH Vibrio cholerae serotype O1 3 0.8527
tRNA-guanine(15) transglycosylase O58843 ATGT_PYRHO Pyrococcus horikoshii 3 0.8461
Ribosomal small subunit pseudouridine synthase A P0AA43 RSUA_ECOLI Escherichia coli 3 0.8446
HTH-type transcriptional repressor PurR P0ACP7 PURR_ECOLI Escherichia coli 3 0.8442
Flavoredoxin Q72HI0 Q72HI0_THET2 Thermus thermophilus 3 0.8417
Queuine tRNA-ribosyltransferase P28720 TGT_ZYMMO Zymomonas mobilis subsp. mobilis 3 0.8381
rRNA methylase Q8DSS3 Q8DSS3_STRMU Streptococcus mutans serotype c 2 0.8361
Queuine tRNA-ribosyltransferase P28720 TGT_ZYMMO Zymomonas mobilis subsp. mobilis 3 0.8341
Toxoflavin degrading enzyme E3SET7 E3SET7_PAEPO Paenibacillus polymyxa 3 0.8244
Basic phospholipase A2 VRV-PL-VIIIa P59071 PA2B8_DABRR Daboia russelii 2 0.8163
Queuine tRNA-ribosyltransferase P28720 TGT_ZYMMO Zymomonas mobilis subsp. mobilis 3 0.8161
DNA-binding transcriptional dual regulator CRP P0ACJ8 CRP_ECOLI Escherichia coli 3 0.8119
HTH-type transcriptional repressor PurR P0ACP7 PURR_ECOLI Escherichia coli 3 0.8079
DNA-binding transcriptional dual regulator CRP P0ACJ8 CRP_ECOLI Escherichia coli 3 0.8048
Trichothecene 15-O-acetyltransferase TRI3 Q9C1B7 TRI3_FUSSP Fusarium sporotrichioides 3 0.8033
cAMP-activated global transcriptional regulator Vfr P55222 VFR_PSEAE Pseudomonas aeruginosa 3 0.8027
Cyclic nucleotide-gated potassium channel mll3241 Q98GN8 CNGK1_RHILO Mesorhizobium japonicum) 3 0.7996
Cyclic nucleotide-binding domain-containing protein E0RR11 E0RR11_SPITD Spirochaeta thermophila 2 0.7996
Purine nucleoside phosphorylase P00491 PNPH_HUMAN Homo sapiens 3 0.7987
DNA-binding transcriptional dual regulator CRP P0ACJ8 CRP_ECOLI Escherichia coli 3 0.7982
DNA-binding transcriptional dual regulator CRP P0ACJ8 CRP_ECOLI Escherichia coli 3 0.7965
DNA-binding transcriptional dual regulator CRP P0ACJ8 CRP_ECOLI Escherichia coli 3 0.7944
NADPH-dependent oxidoreductase 2-alkenal reductase Q39172 AER_ARATH Arabidopsis thaliana 3 0.7937
DNA-binding transcriptional dual regulator CRP P0ACJ8 CRP_ECOLI Escherichia coli 3 0.7912
Thymidylate synthase P0A884 TYSY_ECOLI Escherichia coli 2 0.7885
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 O88703 HCN2_MOUSE Mus musculus 3 0.7882
cGMP-dependent 3',5'-cyclic phosphodiesterase O00408 PDE2A_HUMAN Homo sapiens 3 0.7847
DNA-binding transcriptional dual regulator CRP P0ACJ8 CRP_ECOLI Escherichia coli 3 0.7843
Cyclic nucleotide-gated potassium channel mll3241 Q98GN8 CNGK1_RHILO Mesorhizobium japonicum) 2 0.7826
DNA-binding transcriptional dual regulator CRP P0ACJ8 CRP_ECOLI Escherichia coli 3 0.7825
Ras-related protein Ral-B P11234 RALB_HUMAN Homo sapiens 3 0.7809
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 O88704 HCN1_MOUSE Mus musculus 3 0.7790
DNA-binding transcriptional dual regulator CRP P0ACJ8 CRP_ECOLI Escherichia coli 3 0.7788
Cyclic nucleotide-binding domain-containing protein E0RR11 E0RR11_SPITD Spirochaeta thermophila 3 0.7777
DNA-binding transcriptional dual regulator CRP P0ACJ8 CRP_ECOLI Escherichia coli 3 0.7773
Purine nucleoside phosphorylase DeoD-type P0ABP9 DEOD_ECO57 Escherichia coli O157:H7 3 0.7763
Queuine tRNA-ribosyltransferase P28720 TGT_ZYMMO Zymomonas mobilis subsp. mobilis 3 0.7757
DNA-binding transcriptional dual regulator CRP P0ACJ8 CRP_ECOLI Escherichia coli 3 0.7755
Caffeic acid O-methyltransferase Q9ZTU2 Q9ZTU2_LOLPR Lolium perenne 3 0.7747
RNA-dependent RNA polymerase Q6A562 Q6A562_9VIRU Thosea asigna virus 2 0.7747
DNA-binding transcriptional dual regulator CRP P0ACJ8 CRP_ECOLI Escherichia coli 3 0.7745
5'-methylthioadenosine nucleosidase Q9T0I8 MTN1_ARATH Arabidopsis thaliana 3 0.7743
Cyclin-dependent kinase 2 P24941 CDK2_HUMAN Homo sapiens 3 0.7743
DNA-binding transcriptional dual regulator CRP P0ACJ8 CRP_ECOLI Escherichia coli 3 0.7742
Tetracycline repressor protein class D P0ACT4 TETR4_ECOLX Escherichia coli 2 0.7731
DNA-binding transcriptional dual regulator CRP P0ACJ8 CRP_ECOLI Escherichia coli 3 0.7719
HD domain protein Q836G9 Q836G9_ENTFA Enterococcus faecalis 3 0.7718
Methylmalonyl-CoA decarboxylase P52045 SCPB_ECOLI Escherichia coli 3 0.7717
DNA-binding transcriptional dual regulator CRP P0ACJ8 CRP_ECOLI Escherichia coli 3 0.7707
DNA-binding transcriptional dual regulator CRP P0ACJ8 CRP_ECOLI Escherichia coli 3 0.7701
histidine kinase Q9WZV7 Q9WZV7_THEMA Thermotoga maritima 3 0.7700
Class 10 plant pathogenesis-related protein 2B Q9LLQ2 P102B_LUPLU Lupinus luteus 2 0.7692
cAMP-dependent protein kinase type II-beta regulatory subunit P12369 KAP3_RAT Rattus norvegicus 2 0.7691
cGMP-dependent protein kinase 1 Q13976 KGP1_HUMAN Homo sapiens 2 0.7683
Tetracycline repressor protein class H P51561 TETR8_PASMD Pasteurella multocida 2 0.7682
Carbonic anhydrase 2 P00918 CAH2_HUMAN Homo sapiens 2 0.7679
Precorrin-3 methylase O68097 O68097_RHOCA Rhodobacter capsulatus 3 0.7675
cAMP-dependent protein kinase type I-alpha regulatory subunit P00514 KAP0_BOVIN Bos taurus 2 0.7671
cGMP-dependent protein kinase 2 Q13237 KGP2_HUMAN Homo sapiens 2 0.7666
DNA-binding transcriptional dual regulator CRP P0ACJ8 CRP_ECOLI Escherichia coli 3 0.7665
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 Q9UL51 HCN2_HUMAN Homo sapiens 3 0.7665
ADP-ribosylation factor 1 P84080 ARF1_BOVIN Bos taurus 2 0.7663
Mevalonate kinase P17256 KIME_RAT Rattus norvegicus 3 0.7662
DNA-binding transcriptional dual regulator CRP P0ACJ8 CRP_ECOLI Escherichia coli 3 0.7660
Queuine tRNA-ribosyltransferase P28720 TGT_ZYMMO Zymomonas mobilis subsp. mobilis 3 0.7655
Myosin heavy chain, striated muscle P24733 MYS_ARGIR Argopecten irradians 3 0.7653
DNA-binding transcriptional dual regulator CRP P0ACJ8 CRP_ECOLI Escherichia coli 3 0.7653
DNA-binding transcriptional dual regulator CRP P0ACJ8 CRP_ECOLI Escherichia coli 3 0.7650
DNA-binding transcriptional dual regulator CRP P0ACJ8 CRP_ECOLI Escherichia coli 3 0.7644
Petrobactin biosynthesis protein AsbB Q81RQ8 Q81RQ8_BACAN Bacillus anthracis 3 0.7643
cGMP-dependent protein kinase 1 Q13976 KGP1_HUMAN Homo sapiens 2 0.7641
S-methyl-5'-thioadenosine phosphorylase Q97W94 MTAP_SACS2 Saccharolobus solfataricus 3 0.7639
Ribosome-inactivating protein 3 P25891 RIP3_MAIZE Zea mays 3 0.7633
DNA-binding transcriptional dual regulator CRP P0ACJ8 CRP_ECOLI Escherichia coli 3 0.7631
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase P62617 ISPF_ECOLI Escherichia coli 3 0.7624
3'-5' exoribonuclease Rv2179c P9WJ73 EXRBN_MYCTU Mycobacterium tuberculosis 2 0.7624
Pentaerythritol tetranitrate reductase P71278 P71278_ENTCL Enterobacter cloacae 2 0.7612
cAMP-dependent protein kinase type I-alpha regulatory subunit P00514 KAP0_BOVIN Bos taurus 2 0.7611
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A Q9Y233 PDE10_HUMAN Homo sapiens 3 0.7609
Acyl-CoA:acyl-CoA alkyltransferase Q8PDX2 OLEA_XANCP Xanthomonas campestris pv. campestris 3 0.7606
Beta-galactoside alpha-2,6-sialyltransferase 1 P15907 SIAT1_HUMAN Homo sapiens 3 0.7605
Mitogen-activated protein kinase 8 P45983 MK08_HUMAN Homo sapiens 3 0.7602
Queuine tRNA-ribosyltransferase P28720 TGT_ZYMMO Zymomonas mobilis subsp. mobilis 3 0.7598
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 O88703 HCN2_MOUSE Mus musculus 2 0.7593
DNA-binding transcriptional dual regulator CRP P0ACJ8 CRP_ECOLI Escherichia coli 3 0.7591
Virulence sensor histidine kinase PhoQ P0DM80 PHOQ_SALTY Salmonella typhimurium 3 0.7583
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 Q9Y3Q4 HCN4_HUMAN Homo sapiens 2 0.7582
CCA-adding enzyme O28126 CCA_ARCFU Archaeoglobus fulgidus 2 0.7569
cGMP-dependent protein kinase 1 Q13976 KGP1_HUMAN Homo sapiens 2 0.7566
Thymidylate synthase Q4JQW2 TYSY_VZVO Varicella-zoster virus 3 0.7558
Formylmethanofuran--tetrahydromethanopterin formyltransferase Q49610 FTR_METKA Methanopyrus kandleri 3 0.7555
Ras-related protein Rap-1b P61224 RAP1B_HUMAN Homo sapiens 3 0.7555
Cytidine and deoxycytidylate deaminase zinc-binding region Q82Y41 Q82Y41_NITEU Nitrosomonas europaea 3 0.7553
Argininosuccinate synthase P59846 ASSY_THET8 Thermus thermophilus 3 0.7547
LIM domain kinase 1 P53667 LIMK1_HUMAN Homo sapiens 2 0.7538
Genome polyprotein A9LIE0 A9LIE0_9FLAV dengue virus type 3 3 0.7537
cAMP-dependent protein kinase type I-alpha regulatory subunit P00514 KAP0_BOVIN Bos taurus 2 0.7536
cAMP-dependent protein kinase type I-alpha regulatory subunit P00514 KAP0_BOVIN Bos taurus 2 0.7531
Endoplasmin P41148 ENPL_CANLF Canis lupus familiaris 3 0.7528
Queuine tRNA-ribosyltransferase P28720 TGT_ZYMMO Zymomonas mobilis subsp. mobilis 3 0.7527
L-methionine gamma-lyase P13254 MEGL_PSEPU Pseudomonas putida 3 0.7523
Queuine tRNA-ribosyltransferase P28720 TGT_ZYMMO Zymomonas mobilis subsp. mobilis 3 0.7522
Endoplasmin P41148 ENPL_CANLF Canis lupus familiaris 3 0.7521
3',5'-cyclic-AMP phosphodiesterase 4B Q07343 PDE4B_HUMAN Homo sapiens 3 0.7520
Ethylene receptor 1 P49333 ETR1_ARATH Arabidopsis thaliana 3 0.7519
cAMP-dependent protein kinase type I-alpha regulatory subunit P00514 KAP0_BOVIN Bos taurus 2 0.7518
Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase Q05603 COBT_SALTY Salmonella typhimurium 2 0.7517
Cytidine and deoxycytidylate deaminase zinc-binding region Q82Y41 Q82Y41_NITEU Nitrosomonas europaea 3 0.7515
Beta-glucosidase 12 B8AVF0 BGL12_ORYSI Oryza sativa subsp. indica 2 0.7513
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 Q9Y3Q4 HCN4_HUMAN Homo sapiens 2 0.7513
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 O88703 HCN2_MOUSE Mus musculus 2 0.7510
Queuine tRNA-ribosyltransferase P28720 TGT_ZYMMO Zymomonas mobilis subsp. mobilis 3 0.7509
UDP-galactopyranose mutase Q48485 GLF1_KLEPN Klebsiella pneumoniae 3 0.7501
cGMP-dependent protein kinase 1 P00516 KGP1_BOVIN Bos taurus 3 0.7500
Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial Q8N5Z0 AADAT_HUMAN Homo sapiens 2 0.7498
S-methyl-5'-thioadenosine phosphorylase Q13126 MTAP_HUMAN Homo sapiens 3 0.7497
DNA-binding transcriptional dual regulator CRP P0ACJ8 CRP_ECOLI Escherichia coli 3 0.7496
Photosynthetic reaction center cytochrome c subunit P07173 CYCR_BLAVI Blastochloris viridis 2 0.7494
Beta-1 adrenergic receptor P07700 ADRB1_MELGA Meleagris gallopavo 2 0.7494
Tetracycline repressor protein class D P0ACT4 TETR4_ECOLX Escherichia coli 3 0.7487
Alpha-ketoglutarate-dependent dioxygenase FTO Q9C0B1 FTO_HUMAN Homo sapiens 2 0.7487
Adenosine monophosphate-protein transferase Q8ZVF7 Q8ZVF7_PYRAE Pyrobaculum aerophilum 3 0.7483
Purine nucleoside phosphorylase DeoD-type P0ABP8 DEOD_ECOLI Escherichia coli 2 0.7479
Nucleoside diphosphate kinase Q5UQL3 NDK_MIMIV Acanthamoeba polyphaga mimivirus 2 0.7477
Ribosyldihydronicotinamide dehydrogenase [quinone] P16083 NQO2_HUMAN Homo sapiens 2 0.7472
cAMP-dependent protein kinase type I-alpha regulatory subunit P00514 KAP0_BOVIN Bos taurus 2 0.7472
Cyclic AMP receptor protein Q5SID7 CRP_THET8 Thermus thermophilus 2 0.7472
Argininosuccinate synthase P59846 ASSY_THET8 Thermus thermophilus 3 0.7468
Genome polyprotein Q8QL64 Q8QL64_9FLAV Modoc virus 3 0.7468
Purine nucleoside phosphorylase DeoD-type P0ABP9 DEOD_ECO57 Escherichia coli O157:H7 2 0.7462
Cyclin-dependent kinase 2 P24941 CDK2_HUMAN Homo sapiens 3 0.7461
tRNA (cytidine-2'-O-)-methyltransferase TrmJ Q4JB16 TRMJ_SULAC Sulfolobus acidocaldarius 3 0.7459
Purine nucleoside phosphorylase DeoD-type Q5EEL8 DEOD_BACCE Bacillus cereus 2 0.7451
Heat shock protein HSP 90-alpha P07900 HS90A_HUMAN Homo sapiens 3 0.7448
Endothiapepsin P11838 CARP_CRYPA Cryphonectria parasitica 2 0.7440
Tannase B3Y018 B3Y018_LACPN Lactiplantibacillus plantarum 3 0.7437
Purine nucleoside phosphorylase DeoD-type O34925 DEOD_BACSU Bacillus subtilis 2 0.7433
S-methyl-5'-thioadenosine phosphorylase Q13126 MTAP_HUMAN Homo sapiens 3 0.7428
YbaK/aminoacyl-tRNA synthetase-associated domain-containing protein Q5SHN1 Q5SHN1_THET8 Thermus thermophilus 3 0.7416
CCA-adding enzyme O28126 CCA_ARCFU Archaeoglobus fulgidus 2 0.7415
Cyclin-dependent kinase 8 P49336 CDK8_HUMAN Homo sapiens 2 0.7413
Mitogen-activated protein kinase 8 P45983 MK08_HUMAN Homo sapiens 2 0.7411
Type IV / VI secretion system DotU domain-containing protein Q9KN50 Q9KN50_VIBCH Vibrio cholerae serotype O1 2 0.7408
3-hydroxyanthranilate 3,4-dioxygenase Q1LCS4 3HAO_CUPMC Cupriavidus metallidurans 2 0.7402
Tyrosine-protein kinase SYK P43405 KSYK_HUMAN Homo sapiens 3 0.7395
Mitochondrial poly(A) polymerase F1NBW0 F1NBW0_CHICK Gallus gallus 2 0.7395
Serine/threonine-protein kinase PLK1 P53350 PLK1_HUMAN Homo sapiens 3 0.7393
Class B acid phosphatase Q540U1 APHA_SALTM Salmonella typhimurium 3 0.7392
Purine nucleoside phosphorylase P00491 PNPH_HUMAN Homo sapiens 3 0.7387
Purine nucleoside phosphorylase DeoD-type P0ABP9 DEOD_ECO57 Escherichia coli O157:H7 2 0.7384
Nuclear receptor subfamily 4immunitygroup A member 1 P22736 NR4A1_HUMAN Homo sapiens 2 0.7383
2',3'-cyclic-nucleotide 3'-phosphodiesterase P16330 CN37_MOUSE Mus musculus 2 0.7379
cGMP-dependent protein kinase 1 Q13976 KGP1_HUMAN Homo sapiens 3 0.7378
Flavin-dependent thymidylate synthase Q9WYT0 THYX_THEMA Thermotoga maritima 2 0.7378
Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 Q9Y3Z3 SAMH1_HUMAN Homo sapiens 2 0.7374
Glycogen synthase kinase-3 beta P49841 GSK3B_HUMAN Homo sapiens 2 0.7374
Endoplasmin P41148 ENPL_CANLF Canis lupus familiaris 3 0.7372
Endothiapepsin P11838 CARP_CRYPA Cryphonectria parasitica 2 0.7370
Mitogen-activated protein kinase 8 P45983 MK08_HUMAN Homo sapiens 2 0.7369
Carboxyethyl-arginine beta-lactam-synthase P0DJQ7 BLS_STRCL Streptomyces clavuligerus 3 0.7364
Metallo-beta-lactamase type 2 C7C422 BLAN1_KLEPN Klebsiella pneumoniae 2 0.7363
Cobalamin synthesis related protein Q6NIF5 Q6NIF5_CORDI Corynebacterium diphtheriae 3 0.7361
LD-carboxypeptidase A0A6L8PVW7 A0A1Q4LWC0_BACAN Bacillus anthracis 3 0.7361
Photosynthetic reaction center cytochrome c subunit P07173 CYCR_BLAVI Blastochloris viridis 2 0.7361
Bifunctional epoxide hydrolase 2 P34913 HYES_HUMAN Homo sapiens 2 0.7360
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform P48736 PK3CG_HUMAN Homo sapiens 3 0.7358
Serine/threonine-protein kinase SKY1 Q03656 SKY1_YEAST Saccharomyces cerevisiae 2 0.7358
Purine nucleoside phosphorylase P55859 PNPH_BOVIN Bos taurus 2 0.7357
Spermidine synthase P19623 SPEE_HUMAN Homo sapiens 3 0.7355
Metallo-beta-lactamase type 2 P26918 BLAB_AERHY Aeromonas hydrophila 2 0.7352
cAMP-dependent protein kinase type II-beta regulatory subunit P12369 KAP3_RAT Rattus norvegicus 2 0.7352
Nucleoside diphosphate kinase A 2 P52175 NDKA2_BOVIN Bos taurus 3 0.7351
Queuine tRNA-ribosyltransferase P28720 TGT_ZYMMO Zymomonas mobilis subsp. mobilis 2 0.7351
N-terminal acetyltransferase A complex subunit NAT1 P12945 NAT1_YEAST Saccharomyces cerevisiae 2 0.7350
Purine nucleoside phosphorylase DeoD-type Q5EEL8 DEOD_BACCE Bacillus cereus 2 0.7350
Liver carboxylesterase 1 P23141 EST1_HUMAN Homo sapiens 2 0.7347
Phosphatidylinositol 5-phosphate 4-kinase type-2 beta P78356 PI42B_HUMAN Homo sapiens 3 0.7346
Peroxidase C1A P00433 PER1A_ARMRU Armoracia rusticana 2 0.7346
Ribosyldihydronicotinamide dehydrogenase [quinone] P16083 NQO2_HUMAN Homo sapiens 2 0.7343
Genome polyprotein Q6YMS4 POLG_DEN3S Dengue virus type 3 3 0.7340
Adenylate cyclase 2 A0A2U2H3Y1 A0A384LKY8_YERPE Yersinia pestis 2 0.7340
Plasma membrane ATPase Q42932 Q42932_NICPL Nicotiana plumbaginifolia 2 0.7339
Serine/threonine-protein kinase Chk2 O96017 CHK2_HUMAN Homo sapiens 2 0.7334
ATP-dependent molecular chaperone HSP82 P02829 HSP82_YEAST Saccharomyces cerevisiae 2 0.7330
Heat shock protein HSP 90-alpha P07900 HS90A_HUMAN Homo sapiens 2 0.7327
Sex hormone-binding globulin P04278 SHBG_HUMAN Homo sapiens 2 0.7326
Threonine--tRNA ligase P0A8M3 SYT_ECOLI Escherichia coli 3 0.7325
Queuine tRNA-ribosyltransferase P28720 TGT_ZYMMO Zymomonas mobilis subsp. mobilis 2 0.7325
Metallophosphoesterase A3DJ38 A3DJ38_HUNT2 Clostridium thermocellum 2 0.7323
Glutamate receptor 2 P19491 GRIA2_RAT Rattus norvegicus 2 0.7322
Purine nucleoside phosphorylase Q8I3X4 Q8I3X4_PLAF7 Plasmodium falciparum 2 0.7318
5-methylthioadenosine/S-adenosylhomocysteine deaminase Q7NZ90 Q7NZ90_CHRVO Chromobacterium violaceum 2 0.7315
F420-dependent methylenetetrahydromethanopterin dehydrogenase P94951 MTD_METKA Methanopyrus kandleri 2 0.7312
Phenylalanine-4-hydroxylase P00439 PH4H_HUMAN Homo sapiens 2 0.7312
Dihydropteroate synthase Q81VW8 Q81VW8_BACAN Bacillus anthracis 3 0.7312
Pancreatic alpha-amylase P04746 AMYP_HUMAN Homo sapiens 2 0.7309
Avidin P02701 AVID_CHICK Gallus gallus 2 0.7306
Biotin carboxylase P43873 ACCC_HAEIN Haemophilus influenzae 2 0.7305
Thermolysin P00800 THER_BACTH Bacillus thermoproteolyticus 2 0.7304
L-lactate dehydrogenase A chain P04642 LDHA_RAT Rattus norvegicus 2 0.7303
histone deacetylase A5H660 A5H660_SCHMA Schistosoma mansoni 3 0.7300
Pyridoxal kinase O00764 PDXK_HUMAN Homo sapiens 2 0.7300
Stromelysin-1 P08254 MMP3_HUMAN Homo sapiens 2 0.7299
2-phospho-L-lactate transferase Q8PVT6 COFD_METMA Methanosarcina mazei 2 0.7298
Pentaerythritol tetranitrate reductase P71278 P71278_ENTCL Enterobacter cloacae 2 0.7298
Biflaviolin synthase CYP158A1 Q9KZF5 C1581_STRCO Streptomyces coelicolor / M145) 2 0.7293
3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase P19992 HSD_STREX Streptomyces exfoliatus 2 0.7288
Endothiapepsin P11838 CARP_CRYPA Cryphonectria parasitica 2 0.7287
Albumin P02768 ALBU_HUMAN Homo sapiens 2 0.7285
RIO-type serine/threonine-protein kinase Rio1 O28471 RIO1_ARCFU Archaeoglobus fulgidus 2 0.7281
2',3'-cyclic-nucleotide 3'-phosphodiesterase P16330 CN37_MOUSE Mus musculus 2 0.7280
3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase O33877 FABA_PSEAE Pseudomonas aeruginosa 2 0.7279
DNA-binding transcriptional dual regulator CRP P0ACJ8 CRP_ECOLI Escherichia coli 2 0.7279
L-lactate dehydrogenase A chain P13491 LDHA_RABIT Oryctolagus cuniculus 2 0.7278
Stromelysin-1 P08254 MMP3_HUMAN Homo sapiens 2 0.7272
DNA-directed DNA polymerase Q38087 DPOL_BPR69 Escherichia phage RB69 2 0.7270
Stromelysin-1 P08254 MMP3_HUMAN Homo sapiens 2 0.7270
2',3'-cyclic-nucleotide 3'-phosphodiesterase P16330 CN37_MOUSE Mus musculus 2 0.7267
Ephrin type-B receptor 2 P54763 EPHB2_MOUSE Mus musculus 2 0.7267
Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 Q9Y3Z3 SAMH1_HUMAN Homo sapiens 2 0.7267
Ceramide transfer protein Q9Y5P4 CERT_HUMAN Homo sapiens 2 0.7265
Tannase B3Y018 B3Y018_LACPN Lactiplantibacillus plantarum 3 0.7263
2',3'-cyclic-nucleotide 3'-phosphodiesterase P16330 CN37_MOUSE Mus musculus 2 0.7262
HTH-type transcriptional repressor PurR P0ACP7 PURR_ECOLI Escherichia coli 3 0.7261
HTH-type transcriptional repressor PurR P0ACP7 PURR_ECOLI Escherichia coli 2 0.7258
1-deoxy-D-xylulose 5-phosphate reductoisomerase P45568 DXR_ECOLI Escherichia coli 2 0.7255
BMP-2-inducible protein kinase Q9NSY1 BMP2K_HUMAN Homo sapiens 2 0.7250
Serine/threonine-protein kinase Chk2 O96017 CHK2_HUMAN Homo sapiens 2 0.7248
tRNA (cytidine(34)-2'-O)-methyltransferase P44868 TRML_HAEIN Haemophilus influenzae 3 0.7247
Aminopeptidase N P15145 AMPN_PIG Sus scrofa 2 0.7247
Purine nucleoside phosphorylase DeoD-type O34925 DEOD_BACSU Bacillus subtilis 2 0.7247
Thiazole tautomerase P25053 TENI_BACSU Bacillus subtilis 2 0.7246
Lactotransferrin P24627 TRFL_BOVIN Bos taurus 2 0.7245
Mitogen-activated protein kinase 8 P45983 MK08_HUMAN Homo sapiens 2 0.7244
Capsid protein Q9WBP8 Q9WBP8_9VIRU Adeno-associated virus - 1 2 0.7244
Reaction center protein L chain P0C0Y7 RCEH_RHOSH Rhodobacter sphaeroides 2 0.7244
Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase Q05603 COBT_SALTY Salmonella typhimurium 2 0.7243
2',3'-cyclic-nucleotide 3'-phosphodiesterase P16330 CN37_MOUSE Mus musculus 2 0.7243
Glutamate receptor 2 P19491 GRIA2_RAT Rattus norvegicus 2 0.7242
Purine nucleoside phosphorylase DeoD-type O34925 DEOD_BACSU Bacillus subtilis 2 0.7241
Cyclin-dependent kinase 2 P24941 CDK2_HUMAN Homo sapiens 2 0.7238
2',3'-cyclic-nucleotide 3'-phosphodiesterase P16330 CN37_MOUSE Mus musculus 2 0.7231
HTH-type transcriptional repressor PurR P0ACP7 PURR_ECOLI Escherichia coli 2 0.7231
Cytosolic heat shock protein 90 Q7XJ80 Q7XJ80_HORVU Hordeum vulgare 3 0.7230
Alpha-ketoglutarate-dependent dioxygenase FTO Q9C0B1 FTO_HUMAN Homo sapiens 2 0.7230
Cyclin-dependent kinase 2 P24941 CDK2_HUMAN Homo sapiens 2 0.7224
Casein kinase II subunit alpha P68400 CSK21_HUMAN Homo sapiens 2 0.7222
D-alanyl-D-alanine carboxypeptidase P15555 DAC_STRSR Streptomyces sp 2 0.7217
ADP compounds hydrolase NudE P45799 NUDE_ECOLI Escherichia coli 2 0.7217
Glutamate receptor 3 P19492 GRIA3_RAT Rattus norvegicus 3 0.7216
Uridine phosphorylase Q5XA29 Q5XA29_STRP6 Streptococcus pyogenes serotype M6 3 0.7215
Cyclic GMP-AMP phosphodiesterase SMPDL3A Q92484 ASM3A_HUMAN Homo sapiens 2 0.7210
Proline iminopeptidase O32449 PIP_SERMA Serratia marcescens 2 0.7210
Aspartokinase 1, chloroplastic Q9LYU8 AK1_ARATH Arabidopsis thaliana 3 0.7206
MAP kinase-activated protein kinase 2 P49137 MAPK2_HUMAN Homo sapiens 2 0.7206
Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 Q9Y3Z3 SAMH1_HUMAN Homo sapiens 3 0.7204
Single-stranded-DNA-specific exonuclease RecJ D0EM60 D0EM60_DEIRD Deinococcus radiodurans 2 0.7202
Purine nucleoside phosphorylase P00491 PNPH_HUMAN Homo sapiens 3 0.7201
Tannase B3Y018 B3Y018_LACPN Lactiplantibacillus plantarum 3 0.7198
Uncharacterized protein YML079W Q03629 YMH9_YEAST Saccharomyces cerevisiae 2 0.7197
tRNA-specific 2-thiouridylase MnmA Q97T38 MNMA_STRPN Streptococcus pneumoniae serotype 4 3 0.7195
Vitamin D-binding protein P02774 VTDB_HUMAN Homo sapiens 2 0.7192
Mitogen-activated protein kinase 1 P28482 MK01_HUMAN Homo sapiens 2 0.7190
Carbonic anhydrase 1 P00915 CAH1_HUMAN Homo sapiens 2 0.7189
Gentisate 1,2-dioxygenase Q67FT0 Q67FT0_PSESE Pseudaminobacter salicylatoxidans 2 0.7185
Nitric oxide synthase, inducible P29477 NOS2_MOUSE Mus musculus 2 0.7184
2-aminohexano-6-lactam racemase Q7M181 ACLR_ACHOB Achromobacter obae 2 0.7183
Glutamate receptor 2 P19491 GRIA2_RAT Rattus norvegicus 2 0.7179
2',3'-cyclic-nucleotide 3'-phosphodiesterase P16330 CN37_MOUSE Mus musculus 2 0.7174
N-acetyltransferase domain-containing protein Q9HV14 Q9HV14_PSEAE Pseudomonas aeruginosa 3 0.7173
Pentaerythritol tetranitrate reductase P71278 P71278_ENTCL Enterobacter cloacae 2 0.7169
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 Q9Y3Q4 HCN4_HUMAN Homo sapiens 2 0.7167
Nitric oxide synthase, inducible P29477 NOS2_MOUSE Mus musculus 2 0.7162
adenine phosphoribosyltransferase Q967M2 Q967M2_GIAIN Giardia intestinalis 2 0.7161
Pteridine reductase 1 Q01782 PTR1_LEIMA Leishmania major 2 0.7160
AcsD Q93AT8 Q93AT8_DICCH Dickeya chrysanthemi 3 0.7159
APH(2'')-Id O68183 O68183_ENTCA Enterococcus casseliflavus 3 0.7159
Bis(5'-adenosyl)-triphosphatase P49789 FHIT_HUMAN Homo sapiens 2 0.7155
Aspartate carbamoyltransferase catalytic subunit P0A786 PYRB_ECOLI Escherichia coli 2 0.7155
Abscisic acid receptor PYL9 Q84MC7 PYL9_ARATH Arabidopsis thaliana 2 0.7154
Purine nucleoside phosphorylase DeoD-type B1JL34 DEOD_YERPY Yersinia pseudotuberculosis serotype O:3 2 0.7154
Abscisic acid receptor PYL2 O80992 PYL2_ARATH Arabidopsis thaliana 2 0.7149
Nitric oxide synthase, inducible P29477 NOS2_MOUSE Mus musculus 2 0.7145
Mitogen-activated protein kinase kinase kinase 5 Q99683 M3K5_HUMAN Homo sapiens 2 0.7145
Myosin heavy chain kinase A P42527 MHCKA_DICDI Dictyostelium discoideum 2 0.7141
Nitric oxide synthase, inducible P29477 NOS2_MOUSE Mus musculus 2 0.7132
Dihydropteroate synthase Q81VW8 Q81VW8_BACAN Bacillus anthracis 2 0.7127
Anthranilate phosphoribosyltransferase P00500 TRPD_ACIAD Acinetobacter baylyi 2 0.7126
Fibroblast growth factor receptor 2 P21802 FGFR2_HUMAN Homo sapiens 3 0.7123
L-lactate dehydrogenase A chain P04642 LDHA_RAT Rattus norvegicus 2 0.7121
Protein kinase C iota type Q62074 KPCI_MOUSE Mus musculus 2 0.7121
Nitric oxide synthase oxygenase O34453 NOSO_BACSU Bacillus subtilis 3 0.7119
Sulfotransferase 1A1 P50225 ST1A1_HUMAN Homo sapiens 2 0.7118
Nucleoside 2-deoxyribosyltransferase Q8RLY5 Q8RLY5_LACHE Lactobacillus helveticus 2 0.7117
tRNA-guanine(15) transglycosylase O58843 ATGT_PYRHO Pyrococcus horikoshii 2 0.7114
Flavin-dependent thymidylate synthase Q9WYT0 THYX_THEMA Thermotoga maritima 3 0.7111
Avidin P02701 AVID_CHICK Gallus gallus 2 0.7110
Serine/threonine-protein kinase toxin HipA P23874 HIPA_ECOLI Escherichia coli 2 0.7106
Three-prime repair exonuclease 1 Q91XB0 TREX1_MOUSE Mus musculus 2 0.7104
Albumin P02768 ALBU_HUMAN Homo sapiens 3 0.7102
Succinyl-CoA:acetate CoA-transferase B3EY95 SCACT_ACEAC Acetobacter aceti 2 0.7102
5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase P0AF12 MTNN_ECOLI Escherichia coli 2 0.7100
Coagulation factor X P00742 FA10_HUMAN Homo sapiens 2 0.7096
Prostaglandin F2a synthase Q8I6L9 Q8I6L9_TRYCR Trypanosoma cruzi 2 0.7096
Carbonic anhydrase Q39588 Q39588_CHLRE Chlamydomonas reinhardtii 2 0.7095
Purine nucleoside phosphorylase DeoD-type P0ABP9 DEOD_ECO57 Escherichia coli O157:H7 2 0.7092
Fibroblast growth factor receptor 2 P21802 FGFR2_HUMAN Homo sapiens 2 0.7091
Transcriptional activator, LuxR/UhpA family of regulators Q7NQP7 Q7NQP7_CHRVO Chromobacterium violaceum 2 0.7087
Polyribonucleotide nucleotidyltransferase A7ZS61 PNP_ECO24 Escherichia coli O139:H28 3 0.7086
Proline iminopeptidase O32449 PIP_SERMA Serratia marcescens 2 0.7086
Gag-Pol polyprotein P03369 POL_HV1A2 Human immunodeficiency virus type 1 group M subtype B 2 0.7086
Nucleoside diphosphate kinase A5J299 A5J299_PENVA Penaeus vannamei 2 0.7083
Purine nucleoside phosphorylase DeoD-type Q5EEL8 DEOD_BACCE Bacillus cereus 2 0.7082
Proline iminopeptidase O32449 PIP_SERMA Serratia marcescens 2 0.7081
Class B acid phosphatase P0AE22 APHA_ECOLI Escherichia coli 2 0.7081
Holliday junction branch migration complex subunit RuvB Q9PMT7 RUVB_CAMJE Campylobacter jejuni subsp. jejuni serotype O:2 2 0.7080
Aldo-keto reductase family 1 member B1 P15121 ALDR_HUMAN Homo sapiens 2 0.7078
Acidic phospholipase A2 3 P60045 PA2A3_NAJSG Naja sagittifera 2 0.7076
Thymidine kinase P0DTH5 KITH_HHV11 Human herpesvirus 1 2 0.7076
Queuine tRNA-ribosyltransferase P28720 TGT_ZYMMO Zymomonas mobilis subsp. mobilis 2 0.7075
Nitric oxide synthase, inducible P29477 NOS2_MOUSE Mus musculus 2 0.7071
Snake venom metalloproteinase atrolysin-D P15167 VM1AD_CROAT Crotalus atrox 2 0.7071
Quorum-sensing transcriptional activator Q8XBD0 Q8XBD0_ECO57 Escherichia coli O157:H7 2 0.7068
Serine/threonine-protein kinase Chk1 O14757 CHK1_HUMAN Homo sapiens 2 0.7068
Polymerase acidic protein C3W5S0 C3W5S0_I09A0 Influenza A virus 2 0.7068
Inosine-5'-monophosphate dehydrogenase P50097 IMDH_TRIFO Tritrichomonas foetus 2 0.7067
Serine/threonine-protein kinase 24 Q9Y6E0 STK24_HUMAN Homo sapiens 2 0.7066
Nitric oxide synthase, inducible P29477 NOS2_MOUSE Mus musculus 3 0.7060
Fructose-1,6-bisphosphatase 1 P09467 F16P1_HUMAN Homo sapiens 2 0.7059
Unconventional myosin-Va Q02440 MYO5A_CHICK Gallus gallus 2 0.7057
Acetolactate synthase, chloroplastic P17597 ILVB_ARATH Arabidopsis thaliana 2 0.7052
Heat shock protein HSP 90-alpha P07900 HS90A_HUMAN Homo sapiens 2 0.7052
Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 2 O95340 PAPS2_HUMAN Homo sapiens 2 0.7052
Nitric oxide synthase, inducible P29477 NOS2_MOUSE Mus musculus 3 0.7050
Beta-galactoside-specific lectin 1 P81446 ML1_VISAL Viscum album 2 0.7047
Protocatechuate 3,4-dioxygenase beta chain P00437 PCXB_PSEPU Pseudomonas putida 2 0.7046
Biflaviolin synthase CYP158A2 Q9FCA6 C1582_STRCO Streptomyces coelicolor / M145) 2 0.7044
N-glycosylase/DNA lyase O15527 OGG1_HUMAN Homo sapiens 3 0.7043
Cyclin-dependent kinase 2 P24941 CDK2_HUMAN Homo sapiens 2 0.7035
Uncharacterized protein Q3F0V8 Q3F0V8_BACTI Bacillus thuringiensis serovar israelensis ATCC 35646 3 0.7034
Seed lectin subunit I P05045 LEC1_VIGUC Vigna unguiculata subsp. cylindrica 2 0.7034
Chorismate mutase AroH P19080 AROH_BACSU Bacillus subtilis 2 0.7032
Nitric oxide synthase 1 P29476 NOS1_RAT Rattus norvegicus 3 0.7029
Catechol O-methyltransferase P22734 COMT_RAT Rattus norvegicus 2 0.7028
Rac-like GTP-binding protein ARAC7 O82480 RAC7_ARATH Arabidopsis thaliana 3 0.7027
N-acetyltransferase domain-containing protein Q9HV14 Q9HV14_PSEAE Pseudomonas aeruginosa 2 0.7026
L-seryl-tRNA(Sec) kinase Q58933 PSTK_METJA Methanocaldococcus jannaschii 2 0.7025
Mitogen-activated protein kinase 1 P28482 MK01_HUMAN Homo sapiens 2 0.7022
Norsolorinic acid synthase Q12053 AFLC_ASPPU Aspergillus parasiticus 2 0.7021
4-diphosphocytidyl-2-C-methyl-D-erythritol kinase O67060 ISPE_AQUAE Aquifex aeolicus 2 0.7021
Catalase-peroxidase Q3JNW6 KATG_BURP1 Burkholderia pseudomallei 2 0.7019
Tryptophan synthase alpha chain P00929 TRPA_SALTY Salmonella typhimurium 2 0.7018
S-methyl-5'-thioadenosine phosphorylase Q13126 MTAP_HUMAN Homo sapiens 2 0.7014
Fibroblast growth factor receptor 2 P21802 FGFR2_HUMAN Homo sapiens 2 0.7010
Dihydropteroate synthase Q81VW8 Q81VW8_BACAN Bacillus anthracis 3 0.7009
Pantothenate synthetase P9WIL4 PANC_MYCTO Mycobacterium tuberculosis 2 0.7008
Formate--tetrahydrofolate ligase P21164 FTHS_MOOTH Moorella thermoacetica 2 0.7007
Cyclin-dependent kinase 2 P24941 CDK2_HUMAN Homo sapiens 2 0.7006
Orotidine 5'-phosphate decarboxylase O26232 PYRF_METTH Methanothermobacter thermautotrophicus 3 0.7005
Biflaviolin synthase CYP158A2 Q9FCA6 C1582_STRCO Streptomyces coelicolor / M145) 2 0.7003
Mandelate racemase P11444 MANR_PSEPU Pseudomonas putida 2 0.7003
Endoplasmin P41148 ENPL_CANLF Canis lupus familiaris 2 0.7002
Hexokinase-4 P35557 HXK4_HUMAN Homo sapiens 2 0.7002
Polymerase acidic protein Q5EP34 Q5EP34_9INFA Influenza A virus 2 0.7001
Aromatic-amino-acid aminotransferase P95468 TYRB_PARDE Paracoccus denitrificans 2 0.7001

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