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Monobehenin
- Family: Plantae - Leguminosae/Fabaceae
- Kingdom: Plantae
-
Class: Terpenoid
- Subclass: Diterpene
Canonical Smiles | CCCCCCCCCCCCCCCCCCCCCC(=O)OCC(CO)O |
---|---|
InChI | InChI=1S/C25H50O4/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-21-25(28)29-23-24(27)22-26/h24,26-27H,2-23H2,1H3 |
InChIKey | OKMWKBLSFKFYGZ-UHFFFAOYSA-N |
Formula | C25H50O4 |
HBA | 4 |
HBD | 2 |
MW | 414.67 |
Rotatable Bonds | 23 |
TPSA | 66.76 |
LogP | 6.7 |
Number Rings | 0 |
Number Aromatic Rings | 0 |
Heavy Atom Count | 29 |
Formal Charge | 0 |
Fraction CSP3 | 0.96 |
Exact Mass | 414.37 |
Number of Lipinski Rule Violations | 1 |
# | Species | Family | Kingdom | NCBI Taxonomy ID |
---|---|---|---|---|
1 | Cassia sieberiana | Leguminosae/Fabaceae | Plantae | 1977551 |
Showing of synonyms
Monobehenin
Glyceryl behenate
Behenin
30233-64-8
2,3-Dihydroxypropyl docosanoate
Glyceryl monobehenate
77538-19-3
6916-74-1
Docosanoic acid, 2,3-dihydroxypropyl ester
1,2,3-Propanetriol docosanoate
Docosanoic acid, monoester with 1,2,3-propanetriol
Docosanoic acid, ester with 1,2,3-propanetriol
A626UU0W2A
Glyceryl tribehenate
Glyceryl tridocosanoate
Lipovol GTB
Behenic monoglyceride
Glycerine monobehenate
1-O-Docosanoylglycerol
UNII-A626UU0W2A
Glycerol behenate
1-Monodocosanoin
MG 22:0
1-behenoylglycerol
1-docosanoylglycerol
EINECS 250-097-0
EINECS 278-717-5
1-Monobehenoylglycerol
Docosanoic acid, monoester with glycerol
1-acylglycerol 22:0
Docosanoic acid,2,3-dihydroxypropyl ester
EC 278-717-5
SCHEMBL3805
Glycerol-behenic acid monoester
CHEBI:142497
DTXSID701015809
MAG 22:0
BP-43397
DA-55622
FG145186
DB-217988
DB-254894
Docosanoic acid 2',3'-dihydroxypropyl ester
NS00013665
Q27273676
Pubchem:
5362585
Cas:
30233-64-8
Gnps:
CCMSLIB00003136883
Chebi:
142497
Nmrshiftdb2:
70103628
Metabolights:
MTBLC142497
CPRiL:
101318
No scaffolds available.
No bioactivities available.
Absorption
- Caco-2 (logPapp)
- -5.4
- Human Oral Bioavailability 20%
- Non-Bioavailable
- Human Intestinal Absorption
- Absorbed
- Madin-Darby Canine Kidney
- -3.85
- Human Oral Bioavailability 50%
- Non-Bioavailable
- P-Glycoprotein Inhibitor
- Non-Inhibitor
- P-Glycoprotein Substrate
- Substrate
- Skin Permeability
- -3.34
Distribution
- Blood-Brain Barrier (CNS)
- -
- Blood-Brain Barrier
- Penetrable
- Fraction Unbound (Human)
- 2.02
- Plasma Protein Binding
- 25.44
- Steady State Volume of Distribution
- -
Metabolism
- Breast Cancer Resistance Protein
- Non-Inhibitor
- CYP 1A2 Inhibitor
- Non-Inhibitor
- CYP 1A2 Substrate
- Non-Substrate
- CYP 2C19 Inhibitor
- Non-Inhibitor
- CYP 2C19 Substrate
- Non-Substrate
- CYP 2C9 Inhibitor
- Non-Inhibitor
- CYP 2C9 Substrate
- Non-Substrate
- CYP 2D6 Inhibitor
- Non-Inhibitor
- CYP 2D6 Substrate
- Non-Substrate
- CYP 3A4 Inhibitor
- Non-Inhibitor
- CYP 3A4 Substrate
- Non-Substrate
- OATP1B1
- Non-Inhibitor
- OATP1B3
- Non-Inhibitor
Excretion
- Clearance
- 3.72
- Organic Cation Transporter 2
- Non-Inhibitor
- Half-Life of Drug
- -
Toxicity
- AMES Mutagenesis
- Safe
- Avian
- Safe
- Bee
- Safe
- Bioconcentration Factor
- 0.58
- Biodegradation
- Toxic
- Carcinogenesis
- Safe
- Crustacean
- Toxic
- Liver Injury I (DILI)
- Safe
- Eye Corrosion
- Safe
- Eye Irritation
- Toxic
- Maximum Tolerated Dose
- 2.22
- Liver Injury II
- Safe
- hERG Blockers
- Toxic
- Daphnia Maga
- 4.42
- Micronucleos
- Safe
- NR-AhR
- Safe
- NR-AR
- Safe
- NR-AR-LBD
- Safe
- NR-Aromatase
- Safe
- NR-ER
- Safe
- NR-ER-LBD
- Safe
- NR-GR
- Safe
- NR-PPAR-gamma
- Safe
- NR-TR
- Safe
- T. Pyriformis
- -2.15
- Rat (Acute)
- 1.73
- Rat (Chronic Oral)
- 3.05
- Fathead Minnow
- 4.08
- Respiratory Disease
- Safe
- Skin Sensitisation
- Toxic
- SR-ARE
- Safe
- SR-ATAD5
- Safe
- SR-HSE
- Safe
- SR-MMP
- Safe
- SR-p53
- Safe
General Properties
- Boiling Point
- 457.38
- Hydration Free Energy
- -5.18
- Log(D) at pH=7.4
- 4.74
- Log(P)
- 9.23
- Log S
- -6.36
- Log(Vapor Pressure)
- -9.08
- Melting Point
- 73.17
- pKa Acid
- 10.14
- pKa Basic
- 4.98
Protein Name | UniProt ID | Entry Name | Species | #Pharmacophore Points | Probability (0.7 ≤ Tversky Score ≤ 1.0) |
---|---|---|---|---|---|
Macrophage metalloelastase | P39900 | MMP12_HUMAN | Homo sapiens | 3 | 0.9465 |
Actin, alpha skeletal muscle | P68135 | ACTS_RABIT | Oryctolagus cuniculus | 3 | 0.8902 |
Glucosidase II subunit alpha | Q9STC1 | Q9STC1_GRALE | Gracilariopsis lemaneiformis | 3 | 0.8741 |
Actin, alpha skeletal muscle | P68135 | ACTS_RABIT | Oryctolagus cuniculus | 3 | 0.8134 |
Glycogen synthase | P0A6U8 | GLGA_ECOLI | Escherichia coli | 3 | 0.8036 |
Actin, alpha skeletal muscle | P68135 | ACTS_RABIT | Oryctolagus cuniculus | 3 | 0.8022 |
Iota toxin component Ia | Q46220 | Q46220_CLOPF | Clostridium perfringens | 3 | 0.7905 |
Purine nucleoside phosphorylase DeoD-type | P0ABP8 | DEOD_ECOLI | Escherichia coli | 3 | 0.7898 |
Actin, alpha skeletal muscle | P68135 | ACTS_RABIT | Oryctolagus cuniculus | 3 | 0.7074 |
Putative b-glycan phosphorylase | Q21MB1 | Q21MB1_SACD2 | Saccharophagus degradans | 3 | 0.7020 |
Beta-glucosidase A | Q08638 | BGLA_THEMA | Thermotoga maritima | 3 | 0.7009 |