N-[2-[4-(acetyloxy)-3-methoxyphenyl]ethyl]acetamide - Compound Card

N-[2-[4-(acetyloxy)-3-methoxyphenyl]ethyl]acetamide

Select a section from the left sidebar

N-[2-[4-(acetyloxy)-3-methoxyphenyl]ethyl]acetamide

Structure
Zoomed Structure
  • Family: Plantae - Chenopodiaceae
  • Kingdom: Plantae
  • Class: Alkaloid
Canonical Smiles COc1cc(CCNC(=O)C)ccc1OC(=O)C
InChI InChI=1S/C13H17NO4/c1-9(15)14-7-6-11-4-5-12(18-10(2)16)13(8-11)17-3/h4-5,8H,6-7H2,1-3H3,(H,14,15)
InChIKey WJLSQKNRORLRIX-UHFFFAOYSA-N
Formula C13H17NO4
HBA 4
HBD 1
MW 251.28
Rotatable Bonds 5
TPSA 64.63
LogP 1.3
Number Rings 1
Number Aromatic Rings 1
Heavy Atom Count 18
Formal Charge 0
Fraction CSP3 0.38
Exact Mass 251.12
Number of Lipinski Rule Violations 0
# Species Family Kingdom NCBI Taxonomy ID
1 Haloxylon scoparium Chenopodiaceae Plantae 1665493

Showing of synonyms

  • Lachkar N, Lamchouri F, et al. (2021). Chemical composition, phenolic content and antioxidant capacity of Haloxylon scoparium extracts. Evidence-based complementary and alternative medicine : eCAM, 2021, 2021, 9011168. [View] [PubMed]
Pubchem: 591243

No compound-protein relationship available.

Structure

SMILES: c1ccccc1

Level: 0

Mol. Weight: 251.28 g/mol

No bioactivities available.

Absorption

Caco-2 (logPapp)
-4.56
Human Oral Bioavailability 20%
Bioavailable
Human Intestinal Absorption
Absorbed
Madin-Darby Canine Kidney
-4.240
Human Oral Bioavailability 50%
Bioavailable
P-Glycoprotein Inhibitor
Non-Inhibitor
P-Glycoprotein Substrate
Non-Substrate
Skin Permeability
-2.88

Distribution

Blood-Brain Barrier (CNS)
-
Blood-Brain Barrier
Penetrable
Fraction Unbound (Human)
0.360
Plasma Protein Binding
21.63
Steady State Volume of Distribution
-

Metabolism

Breast Cancer Resistance Protein
Non-Inhibitor
CYP 1A2 Inhibitor
Non-Inhibitor
CYP 1A2 Substrate
Substrate
CYP 2C19 Inhibitor
Non-Inhibitor
CYP 2C19 Substrate
Non-Substrate
CYP 2C9 Inhibitor
Non-Inhibitor
CYP 2C9 Substrate
Non-Substrate
CYP 2D6 Inhibitor
Non-Inhibitor
CYP 2D6 Substrate
Substrate
CYP 3A4 Inhibitor
Non-Inhibitor
CYP 3A4 Substrate
Non-Substrate
OATP1B1
Non-Inhibitor
OATP1B3
Non-Inhibitor

Excretion

Clearance
6.760
Organic Cation Transporter 2
Non-Inhibitor
Half-Life of Drug
-

Toxicity

AMES Mutagenesis
Safe
Avian
Safe
Bee
Toxic
Bioconcentration Factor
0.610
Biodegradation
Toxic
Carcinogenesis
Safe
Crustacean
Safe
Liver Injury I (DILI)
Safe
Eye Corrosion
Safe
Eye Irritation
Safe
Maximum Tolerated Dose
1.420
Liver Injury II
Toxic
hERG Blockers
Safe
Daphnia Maga
4.430
Micronucleos
Toxic
NR-AhR
Safe
NR-AR
Safe
NR-AR-LBD
Safe
NR-Aromatase
Safe
NR-ER
Safe
NR-ER-LBD
Safe
NR-GR
Safe
NR-PPAR-gamma
Safe
NR-TR
Safe
T. Pyriformis
2.220
Rat (Acute)
2.110
Rat (Chronic Oral)
1.700
Fathead Minnow
4.030
Respiratory Disease
Safe
Skin Sensitisation
Safe
SR-ARE
Safe
SR-ATAD5
Safe
SR-HSE
Safe
SR-MMP
Safe
SR-p53
Safe

General Properties

Boiling Point
334.120
Hydration Free Energy
-11.410
Log(D) at pH=7.4
0.990
Log(P)
0.79
Log S
-1.44
Log(Vapor Pressure)
-5.31
Melting Point
92.84
pKa Acid
10.84
pKa Basic
5.63
Protein Name UniProt ID Entry Name Species #Pharmacophore Points Probability (0.7 ≤ Tversky Score ≤ 1.0)
3'-5' exoribonuclease Rv2179c P9WJ73 EXRBN_MYCTU Mycobacterium tuberculosis 3 0.9912
Pentaerythritol tetranitrate reductase P71278 P71278_ENTCL Enterobacter cloacae 3 0.9765
Carbonic anhydrase 2 P00918 CAH2_HUMAN Homo sapiens 3 0.9642
2-phospho-L-lactate transferase Q8PVT6 COFD_METMA Methanosarcina mazei 3 0.9614
Sulfotransferase 1A1 P50225 ST1A1_HUMAN Homo sapiens 3 0.9443
Heat shock protein HSP 90-alpha P07900 HS90A_HUMAN Homo sapiens 3 0.9394
Norsolorinic acid synthase Q12053 AFLC_ASPPU Aspergillus parasiticus 3 0.9279
NAD-capped RNA hydrolase NudC P32664 NUDC_ECOLI Escherichia coli 3 0.9188
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A Q9Y233 PDE10_HUMAN Homo sapiens 3 0.9164
Heat shock protein HSP 90-alpha P07900 HS90A_HUMAN Homo sapiens 3 0.9157
Pantothenate synthetase P9WIL5 PANC_MYCTU Mycobacterium tuberculosis 3 0.9151
2-phospho-L-lactate transferase Q8PVT6 COFD_METMA Methanosarcina mazei 3 0.9145
Glutamate receptor 2 P19491 GRIA2_RAT Rattus norvegicus 3 0.9123
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform P48736 PK3CG_HUMAN Homo sapiens 3 0.9091
Glutamate receptor 2 P19491 GRIA2_RAT Rattus norvegicus 3 0.9039
D-aminoacyl-tRNA deacylase Q8IIS0 DTD_PLAF7 Plasmodium falciparum 3 0.9030
Glycogen synthase kinase-3 beta P49841 GSK3B_HUMAN Homo sapiens 3 0.8997
Photosynthetic reaction center cytochrome c subunit P07173 CYCR_BLAVI Blastochloris viridis 3 0.8980
Glutamate receptor 2 P19491 GRIA2_RAT Rattus norvegicus 3 0.8965
N-alpha-acetyltransferase 50 Q9GZZ1 NAA50_HUMAN Homo sapiens 4 0.8905
Glutamate receptor 3 P19492 GRIA3_RAT Rattus norvegicus 4 0.8874
Glycogen synthase kinase-3 beta P49841 GSK3B_HUMAN Homo sapiens 3 0.8864
Cyclin-dependent kinase 2 P24941 CDK2_HUMAN Homo sapiens 3 0.8857
Glutamate receptor 2 P19491 GRIA2_RAT Rattus norvegicus 4 0.8788
Cyclin-dependent kinase 8 P49336 CDK8_HUMAN Homo sapiens 3 0.8666
DNA gyrase subunit A P0AES5 GYRA_SHIFL Shigella flexneri 3 0.8622
Photosynthetic reaction center cytochrome c subunit P07173 CYCR_BLAVI Blastochloris viridis 3 0.8499
Serine/threonine-protein kinase Chk1 O14757 CHK1_HUMAN Homo sapiens 4 0.8459
NADPH dehydrogenase 1 Q02899 OYE1_SACPS Saccharomyces pastorianus 3 0.8424
Cyclin-dependent kinase 2 P24941 CDK2_HUMAN Homo sapiens 3 0.8405
Purine nucleoside phosphorylase P00491 PNPH_HUMAN Homo sapiens 3 0.8306
ADP-ribosylation factor 1 P84080 ARF1_BOVIN Bos taurus 3 0.8256
Tetracycline repressor protein class D P0ACT4 TETR4_ECOLX Escherichia coli 3 0.8102
ADP-ribosylation factor 1 P84077 ARF1_HUMAN Homo sapiens 2 0.8078
Carbonic anhydrase 1 P00915 CAH1_HUMAN Homo sapiens 3 0.8076
Basic phospholipase A2 VRV-PL-VIIIa P59071 PA2B8_DABRR Daboia russelii 2 0.8046
Cyclin-dependent kinase 2 P24941 CDK2_HUMAN Homo sapiens 3 0.8035
Cyclin-dependent kinase 2 P24941 CDK2_HUMAN Homo sapiens 3 0.7985
Gag-Pol polyprotein P03369 POL_HV1A2 Human immunodeficiency virus type 1 group M subtype B 3 0.7983
HTH-type transcriptional repressor PurR P0ACP7 PURR_ECOLI Escherichia coli 3 0.7785
Cyclin-dependent kinase 2 P24941 CDK2_HUMAN Homo sapiens 3 0.7750
Vascular endothelial growth factor receptor 2 P35968 VGFR2_HUMAN Homo sapiens 3 0.7744
16S rRNA (guanine(1405)-N(7))-methyltransferase Q763K9 Q763K9_ECOLX Escherichia coli 3 0.7722
Type II methyltransferase M.TaqI P14385 MTTA_THEAQ Thermus aquaticus 3 0.7720
Endoplasmin P41148 ENPL_CANLF Canis lupus familiaris 3 0.7718
Peroxidase C1A P00433 PER1A_ARMRU Armoracia rusticana 2 0.7713
Caffeic acid O-methyltransferase Q9ZTU2 Q9ZTU2_LOLPR Lolium perenne 3 0.7684
Methyltransferase type 12 Q88JU2 Q88JU2_PSEPK Pseudomonas putida 3 0.7676
Thymidylate synthase Q4JQW2 TYSY_VZVO Varicella-zoster virus 3 0.7673
Nitric oxide synthase 3 P29474 NOS3_HUMAN Homo sapiens 3 0.7671
3',5'-cyclic-AMP phosphodiesterase 4B Q07343 PDE4B_HUMAN Homo sapiens 4 0.7645
RNA-dependent RNA polymerase Q6A562 Q6A562_9VIRU Thosea asigna virus 2 0.7644
Adenosine kinase Q9TVW2 ADK_TOXGO Toxoplasma gondii 3 0.7636
Serine/threonine-protein kinase Chk1 O14757 CHK1_HUMAN Homo sapiens 3 0.7635
Lipoyl synthase 2 Q8DLC2 LIPA2_THEEB Thermosynechococcus vestitus 4 0.7609
Tetracycline repressor protein class D P0ACT4 TETR4_ECOLX Escherichia coli 2 0.7605
Cytochrome b-c1 complex subunit 1, mitochondrial P31800 QCR1_BOVIN Bos taurus 3 0.7599
Chloramphenicol 3-O phosphotransferase Q56148 CPT_STRVP Streptomyces venezuelae 3 0.7598
Endothiapepsin P11838 CARP_CRYPA Cryphonectria parasitica 3 0.7595
Serine/threonine-protein kinase Chk1 O14757 CHK1_HUMAN Homo sapiens 3 0.7585
HTH-type transcriptional repressor PurR P0ACP7 PURR_ECOLI Escherichia coli 3 0.7585
Hexokinase-4 P35557 HXK4_HUMAN Homo sapiens 3 0.7580
Beta-1 adrenergic receptor P07700 ADRB1_MELGA Meleagris gallopavo 3 0.7576
NADPH-dependent 7-cyano-7-deazaguanine reductase Q9KTK0 QUEF_VIBCH Vibrio cholerae serotype O1 3 0.7564
cAMP-dependent protein kinase type I-alpha regulatory subunit P00514 KAP0_BOVIN Bos taurus 2 0.7539
4-hydroxyphenylacetate 3-monooxygenase, reductase component Q5SJP7 HPAC_THET8 Thermus thermophilus 3 0.7533
Polyprotein Q80J95 Q80J95_9CALI Murine norovirus 1 2 0.7533
CCA-adding enzyme O28126 CCA_ARCFU Archaeoglobus fulgidus 2 0.7524
Tetracycline repressor protein class H P51561 TETR8_PASMD Pasteurella multocida 2 0.7523
Nitric oxide synthase oxygenase O34453 NOSO_BACSU Bacillus subtilis 3 0.7522
Aurora kinase A O14965 AURKA_HUMAN Homo sapiens 3 0.7520
tRNA-guanine(15) transglycosylase O58843 ATGT_PYRHO Pyrococcus horikoshii 3 0.7509
HTH-type transcriptional repressor PurR P0ACP7 PURR_ECOLI Escherichia coli 3 0.7493
Nucleoside permease Q9KPL5 Q9KPL5_VIBCH Vibrio cholerae serotype O1 3 0.7489
Purine nucleoside phosphorylase P00491 PNPH_HUMAN Homo sapiens 3 0.7484
N-acetyltransferase domain-containing protein Q9HV14 Q9HV14_PSEAE Pseudomonas aeruginosa 3 0.7482
Type II methyltransferase M.TaqI P14385 MTTA_THEAQ Thermus aquaticus 3 0.7472
Matrix metalloproteinase-20 O60882 MMP20_HUMAN Homo sapiens 3 0.7463
L-methionine gamma-lyase Q84AR1 Q84AR1_CITFR Citrobacter freundii 3 0.7456
Adenylate cyclase type 5 P30803 ADCY5_CANLF Canis lupus familiaris 3 0.7449
2',3'-cyclic-nucleotide 3'-phosphodiesterase P16330 CN37_MOUSE Mus musculus 2 0.7437
Catechol O-methyltransferase P22734 COMT_RAT Rattus norvegicus 3 0.7431
Phosphatidylinositol 5-phosphate 4-kinase type-2 beta P78356 PI42B_HUMAN Homo sapiens 3 0.7424
Aurora kinase A O14965 AURKA_HUMAN Homo sapiens 3 0.7423
Cytidine deaminase P19079 CDD_BACSU Bacillus subtilis 3 0.7418
Streptavidin P22629 SAV_STRAV Streptomyces avidinii 3 0.7410
Putative S-adenosyl-L-methionine-dependent methyltransferase ML2640 Q9CCZ4 Y2640_MYCLE Mycobacterium leprae 3 0.7409
NADPH-dependent oxidoreductase 2-alkenal reductase Q39172 AER_ARATH Arabidopsis thaliana 2 0.7404
HTH-type transcriptional repressor PurR P0ACP7 PURR_ECOLI Escherichia coli 3 0.7404
Nuclear receptor subfamily 4immunitygroup A member 1 P22736 NR4A1_HUMAN Homo sapiens 2 0.7403
APH(2'')-Id O68183 O68183_ENTCA Enterococcus casseliflavus 3 0.7400
cGMP-dependent protein kinase 1 Q13976 KGP1_HUMAN Homo sapiens 2 0.7392
Purine nucleoside phosphorylase DeoD-type O34925 DEOD_BACSU Bacillus subtilis 2 0.7386
cAMP-dependent protein kinase type II-beta regulatory subunit P12369 KAP3_RAT Rattus norvegicus 2 0.7384
cGMP-dependent protein kinase 1 Q13976 KGP1_HUMAN Homo sapiens 2 0.7381
Polyamine aminopropyltransferase Q5SK28 SPEE_THET8 Thermus thermophilus 3 0.7379
Metallo-beta-lactamase type 2 P26918 BLAB_AERHY Aeromonas hydrophila 2 0.7368
Mitogen-activated protein kinase 8 P45983 MK08_HUMAN Homo sapiens 2 0.7368
HTH-type transcriptional repressor PurR P0ACP7 PURR_ECOLI Escherichia coli 3 0.7366
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A Q9Y233 PDE10_HUMAN Homo sapiens 3 0.7364
Soluble cytochrome b562 P0ABE7 C562_ECOLX Escherichia coli 3 0.7363
Aurora kinase A O14965 AURKA_HUMAN Homo sapiens 3 0.7356
cAMP-dependent protein kinase type I-alpha regulatory subunit P00514 KAP0_BOVIN Bos taurus 2 0.7345
Ceramide transfer protein Q9Y5P4 CERT_HUMAN Homo sapiens 2 0.7344
Phenylalanine-4-hydroxylase P00439 PH4H_HUMAN Homo sapiens 2 0.7332
Mitochondrial poly(A) polymerase F1NBW0 F1NBW0_CHICK Gallus gallus 2 0.7330
Sex hormone-binding globulin P04278 SHBG_HUMAN Homo sapiens 2 0.7329
Release factor glutamine methyltransferase Q9WYV8 PRMC_THEMA Thermotoga maritima 3 0.7327
Cyclic AMP receptor protein Q5SID7 CRP_THET8 Thermus thermophilus 2 0.7327
Serine/threonine-protein kinase PLK1 P53350 PLK1_HUMAN Homo sapiens 3 0.7326
Guanylate kinase Q83EL7 KGUA_COXBU Coxiella burnetii 4 0.7324
Mitogen-activated protein kinase 8 P45983 MK08_HUMAN Homo sapiens 2 0.7324
Pancreatic alpha-amylase P04746 AMYP_HUMAN Homo sapiens 2 0.7315
Nitric oxide synthase, inducible P29477 NOS2_MOUSE Mus musculus 3 0.7308
Polymerase acidic protein C3W5S0 C3W5S0_I09A0 Influenza A virus 2 0.7304
Mycocyclosin synthase P9WPP7 CP121_MYCTU Mycobacterium tuberculosis 2 0.7304
LIM domain kinase 1 P53667 LIMK1_HUMAN Homo sapiens 2 0.7302
Type II methyltransferase M.HhaI P05102 MTH1_HAEPH Haemophilus parahaemolyticus 3 0.7301
Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial Q8N5Z0 AADAT_HUMAN Homo sapiens 2 0.7300
Lactotransferrin P24627 TRFL_BOVIN Bos taurus 2 0.7294
3-phosphoinositide-dependent protein kinase 1 O15530 PDPK1_HUMAN Homo sapiens 3 0.7293
16S rRNA (adenine(1408)-N(1))-methyltransferase A8C927 NPMA_ECOLX Escherichia coli 3 0.7292
5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase 1 O50008 METE1_ARATH Arabidopsis thaliana 2 0.7291
Adenylate cyclase type 5 P30803 ADCY5_CANLF Canis lupus familiaris 3 0.7287
Deoxycytidine kinase P27707 DCK_HUMAN Homo sapiens 3 0.7286
Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 Q9Y3Z3 SAMH1_HUMAN Homo sapiens 2 0.7286
DNA polymerase III subunit epsilon P03007 DPO3E_ECOLI Escherichia coli 2 0.7284
Serine/threonine-protein kinase SKY1 Q03656 SKY1_YEAST Saccharomyces cerevisiae 2 0.7279
Dihydropteroate synthase Q81VW8 Q81VW8_BACAN Bacillus anthracis 3 0.7277
2',3'-cyclic-nucleotide 3'-phosphodiesterase P16330 CN37_MOUSE Mus musculus 2 0.7276
Pentaerythritol tetranitrate reductase P71278 P71278_ENTCL Enterobacter cloacae 2 0.7276
N-terminal acetyltransferase A complex subunit NAT1 P12945 NAT1_YEAST Saccharomyces cerevisiae 2 0.7273
Capsid protein Q9WBP8 Q9WBP8_9VIRU Adeno-associated virus - 1 2 0.7270
Nitric oxide synthase, inducible P29477 NOS2_MOUSE Mus musculus 3 0.7265
Flavin reductase like domain-containing protein Q4UKE8 Q4UKE8_RICFE Rickettsia felis 3 0.7260
Cyclic nucleotide-gated potassium channel mll3241 Q98GN8 CNGK1_RHILO Mesorhizobium japonicum) 2 0.7259
Serine/threonine-protein kinase Chk1 O14757 CHK1_HUMAN Homo sapiens 3 0.7257
Reaction center protein L chain P0C0Y7 RCEH_RHOSH Rhodobacter sphaeroides 2 0.7257
Aurora kinase A O14965 AURKA_HUMAN Homo sapiens 3 0.7251
Thymidylate synthase P00469 TYSY_LACCA Lacticaseibacillus casei 3 0.7248
Endothiapepsin P11838 CARP_CRYPA Cryphonectria parasitica 2 0.7247
Nitric oxide synthase, inducible P29477 NOS2_MOUSE Mus musculus 3 0.7245
Nitric oxide synthase 1 P29476 NOS1_RAT Rattus norvegicus 3 0.7245
Nucleoside diphosphate kinase Q5UQL3 NDK_MIMIV Acanthamoeba polyphaga mimivirus 2 0.7245
Mitogen-activated protein kinase 1 P28482 MK01_HUMAN Homo sapiens 2 0.7234
Phenylalanine-4-hydroxylase P00439 PH4H_HUMAN Homo sapiens 3 0.7228
ATP-dependent molecular chaperone HSP82 P02829 HSP82_YEAST Saccharomyces cerevisiae 2 0.7228
Gag-Pol polyprotein P05896 POL_SIVM1 Simian immunodeficiency virus 3 0.7225
DNA-directed DNA polymerase Q38087 DPOL_BPR69 Escherichia phage RB69 2 0.7225
Pteridine reductase, putative Q581W1 Q581W1_TRYB2 Trypanosoma brucei brucei 3 0.7223
Beta-galactoside-specific lectin 4 Q6ITZ3 ML4_VISAL Viscum album 2 0.7222
BMP-2-inducible protein kinase Q9NSY1 BMP2K_HUMAN Homo sapiens 2 0.7221
Queuine tRNA-ribosyltransferase P28720 TGT_ZYMMO Zymomonas mobilis subsp. mobilis 3 0.7217
Bifunctional epoxide hydrolase 2 P34913 HYES_HUMAN Homo sapiens 2 0.7215
Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase Q05603 COBT_SALTY Salmonella typhimurium 2 0.7211
Mitogen-activated protein kinase 8 P45983 MK08_HUMAN Homo sapiens 2 0.7209
2',3'-cyclic-nucleotide 3'-phosphodiesterase P16330 CN37_MOUSE Mus musculus 2 0.7207
Alpha-ketoglutarate-dependent dioxygenase FTO Q9C0B1 FTO_HUMAN Homo sapiens 2 0.7195
Nitric oxide synthase, inducible P29477 NOS2_MOUSE Mus musculus 3 0.7189
L-lactate dehydrogenase A chain P13491 LDHA_RABIT Oryctolagus cuniculus 2 0.7189
Nicotinamide phosphoribosyltransferase P43490 NAMPT_HUMAN Homo sapiens 2 0.7180
MAP kinase-activated protein kinase 2 P49137 MAPK2_HUMAN Homo sapiens 2 0.7172
Pteridine reductase 1 Q01782 PTR1_LEIMA Leishmania major 2 0.7172
Endothiapepsin P11838 CARP_CRYPA Cryphonectria parasitica 2 0.7164
Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 Q9Y3Z3 SAMH1_HUMAN Homo sapiens 2 0.7160
Ferrichrome outer membrane transporter/phage receptor P06971 FHUA_ECOLI Escherichia coli 3 0.7157
5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase P0AF12 MTNN_ECOLI Escherichia coli 2 0.7157
2',3'-cyclic-nucleotide 3'-phosphodiesterase P16330 CN37_MOUSE Mus musculus 2 0.7157
Metallo-beta-lactamase type 2 C7C422 BLAN1_KLEPN Klebsiella pneumoniae 2 0.7153
Nitric oxide synthase, inducible P29477 NOS2_MOUSE Mus musculus 3 0.7151
Ribonuclease 4 P15468 RNAS4_PIG Sus scrofa 2 0.7147
11-beta-hydroxysteroid dehydrogenase 1 P28845 DHI1_HUMAN Homo sapiens 2 0.7146
Geranyl diphosphate 2-C-methyltransferase D3KYU3 GPPMT_STRLS Streptomyces lasalocidi 3 0.7133
Metallophosphoesterase A3DJ38 A3DJ38_HUNT2 Clostridium thermocellum 2 0.7124
2',3'-cyclic-nucleotide 3'-phosphodiesterase P16330 CN37_MOUSE Mus musculus 2 0.7123
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 O88703 HCN2_MOUSE Mus musculus 2 0.7123
Serine/threonine-protein kinase Chk1 O14757 CHK1_HUMAN Homo sapiens 3 0.7117
Aminopeptidase N P15145 AMPN_PIG Sus scrofa 2 0.7117
Cyclin-dependent kinase 9 P50750 CDK9_HUMAN Homo sapiens 3 0.7116
Fibroblast growth factor receptor 2 P21802 FGFR2_HUMAN Homo sapiens 2 0.7114
Orotidine 5'-phosphate decarboxylase Q5L0U0 PYRF_GEOKA Geobacillus kaustophilus 3 0.7112
Cyclic nucleotide-binding domain-containing protein E0RR11 E0RR11_SPITD Spirochaeta thermophila 2 0.7111
Chloramphenicol 3-O phosphotransferase Q56148 CPT_STRVP Streptomyces venezuelae 2 0.7110
Sulfotransferase 1A1 P50225 ST1A1_HUMAN Homo sapiens 3 0.7109
PTS system glucose-specific EIIA component P69783 PTGA_ECOLI Escherichia coli 3 0.7105
cAMP-dependent protein kinase type I-alpha regulatory subunit P00514 KAP0_BOVIN Bos taurus 2 0.7086
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 O88703 HCN2_MOUSE Mus musculus 2 0.7083
D-alanyl-D-alanine carboxypeptidase P15555 DAC_STRSR Streptomyces sp 2 0.7080
Ribosomal RNA small subunit methyltransferase E Q5SKI6 Q5SKI6_THET8 Thermus thermophilus 3 0.7079
Proto-oncogene tyrosine-protein kinase receptor Ret P07949 RET_HUMAN Homo sapiens 3 0.7076
Queuine tRNA-ribosyltransferase P28720 TGT_ZYMMO Zymomonas mobilis subsp. mobilis 3 0.7072
chitinase B0Y2Y2 B0Y2Y2_ASPFC Aspergillus fumigatus 3 0.7071
Type IV / VI secretion system DotU domain-containing protein Q9KN50 Q9KN50_VIBCH Vibrio cholerae serotype O1 2 0.7064
Malate synthase G P9WK17 MASZ_MYCTU Mycobacterium tuberculosis 3 0.7060
Cyclin-dependent kinase 9 P50750 CDK9_HUMAN Homo sapiens 3 0.7058
Archaeal actin homolog Q9HKL4 ACTH_THEAC Thermoplasma acidophilum 2 0.7056
Liver carboxylesterase 1 P23141 EST1_HUMAN Homo sapiens 2 0.7049
cAMP-dependent protein kinase type II-beta regulatory subunit P12369 KAP3_RAT Rattus norvegicus 2 0.7041
4-hydroxy-7-methoxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl glucoside beta-D-glucosidase, chloroplastic Q9FYS3 HGGL_SECCE Secale cereale 3 0.7040
Cyclin-dependent kinase 2 P24941 CDK2_HUMAN Homo sapiens 2 0.7036
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 Q9Y3Q4 HCN4_HUMAN Homo sapiens 2 0.7033
Ephrin type-B receptor 2 P54763 EPHB2_MOUSE Mus musculus 2 0.7031
Alpha/beta hydrolase fold A5VAT9 A5VAT9_SPHWW Sphingomonas wittichii 2 0.7030
Purine nucleoside phosphorylase DeoD-type Q5EEL8 DEOD_BACCE Bacillus cereus 2 0.7022
Stromelysin-1 P08254 MMP3_HUMAN Homo sapiens 2 0.7020
Endothiapepsin P11838 CARP_CRYPA Cryphonectria parasitica 2 0.7019
cGMP-dependent protein kinase 2 Q13237 KGP2_HUMAN Homo sapiens 2 0.7019
3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase P19992 HSD_STREX Streptomyces exfoliatus 2 0.7010
Cyclin-dependent kinase 2 P24941 CDK2_HUMAN Homo sapiens 3 0.7009
DNA (cytosine-5)-methyltransferase 1 Q9AXT8 H32_ARATH Zea mays 3 0.7009

Download SDF