Scutellarein 8-C-beta-D-glucopyranoside - Compound Card

Scutellarein 8-C-beta-D-glucopyranoside

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Scutellarein 8-C-beta-D-glucopyranoside

Structure
Zoomed Structure
  • Family: Cistaceae
  • Kingdom: Plantae
  • Class: Flavonoid
    • Subclass: Flavone Glycoside
Canonical Smiles OC(=O)CC[C@@H](C(=O)Oc1c(O)c(O)c(c2c1oc(cc2=O)c1ccc(cc1)O)O)N
InChI InChI=1S/C20H17NO10/c21-10(5-6-13(24)25)20(29)31-19-17(28)16(27)15(26)14-11(23)7-12(30-18(14)19)8-1-3-9(22)4-2-8/h1-4,7,10,22,26-28H,5-6,21H2,(H,24,25)/t10-/m0/s1
InChIKey JMDXUAYUDOBQDX-JTQLQIEISA-N
Formula C20H17NO10
HBA 10
HBD 6
MW 431.35
Rotatable Bonds 6
TPSA 200.75
LogP 1.38
Number Rings 3
Number Aromatic Rings 3
Heavy Atom Count 31
Formal Charge 0
Fraction CSP3 0.15
Exact Mass 431.09
Number of Lipinski Rule Violations 1
# Species Family Kingdom NCBI Taxonomy ID
1 Helianthemum getulum Cistaceae Plantae 2020754

Showing of synonyms

  • Terfassi S, Dauvergne X, et al. (2022). First report on phytochemical investigation, antioxidant and antidiabetic activities of Helianthemum getulum. Natural product research, 2022, 36(11), 2806-2813. [View] [PubMed]

No compound-protein relationship available.

Structure

SMILES: c1cccc(c12)oc(cc2=O)-c3ccccc3

Level: 1

Mol. Weight: 222.24 g/mol

Structure

SMILES: c1cccc(c12)occc2=O

Level: 0

Mol. Weight: 146.14 g/mol

Structure

SMILES: c1ccccc1

Level: 0

Mol. Weight: 78.11 g/mol

No bioactivities available.

Absorption

Caco-2 (logPapp)
-6.79
Human Oral Bioavailability 20%
Non-Bioavailable
Human Intestinal Absorption
Absorbed
Madin-Darby Canine Kidney
-5.25
Human Oral Bioavailability 50%
Non-Bioavailable
P-Glycoprotein Inhibitor
Non-Inhibitor
P-Glycoprotein Substrate
Non-Substrate
Skin Permeability
-0.02

Distribution

Blood-Brain Barrier (CNS)
-
Blood-Brain Barrier
Non-Penetrable
Fraction Unbound (Human)
1.23
Plasma Protein Binding
64.63
Steady State Volume of Distribution
-

Metabolism

Breast Cancer Resistance Protein
Inhibitor
CYP 1A2 Inhibitor
Inhibitor
CYP 1A2 Substrate
Non-Substrate
CYP 2C19 Inhibitor
Non-Inhibitor
CYP 2C19 Substrate
Non-Substrate
CYP 2C9 Inhibitor
Non-Inhibitor
CYP 2C9 Substrate
Substrate
CYP 2D6 Inhibitor
Non-Inhibitor
CYP 2D6 Substrate
Non-Substrate
CYP 3A4 Inhibitor
Non-Inhibitor
CYP 3A4 Substrate
Non-Substrate
OATP1B1
Non-Inhibitor
OATP1B3
Non-Inhibitor

Excretion

Clearance
9.35
Organic Cation Transporter 2
Inhibitor
Half-Life of Drug
-

Toxicity

AMES Mutagenesis
Safe
Avian
Safe
Bee
Safe
Bioconcentration Factor
-1.06
Biodegradation
Safe
Carcinogenesis
Safe
Crustacean
Safe
Liver Injury I (DILI)
Toxic
Eye Corrosion
Safe
Eye Irritation
Safe
Maximum Tolerated Dose
1.03
Liver Injury II
Toxic
hERG Blockers
Safe
Daphnia Maga
6.52
Micronucleos
Toxic
NR-AhR
Toxic
NR-AR
Safe
NR-AR-LBD
Safe
NR-Aromatase
Safe
NR-ER
Safe
NR-ER-LBD
Safe
NR-GR
Safe
NR-PPAR-gamma
Safe
NR-TR
Safe
T. Pyriformis
-27.96
Rat (Acute)
2.39
Rat (Chronic Oral)
3.56
Fathead Minnow
4.32
Respiratory Disease
Safe
Skin Sensitisation
Safe
SR-ARE
Toxic
SR-ATAD5
Safe
SR-HSE
Safe
SR-MMP
Safe
SR-p53
Safe

General Properties

Boiling Point
577.44
Hydration Free Energy
-7.25
Log(D) at pH=7.4
-0.6
Log(P)
-0.49
Log S
-3.79
Log(Vapor Pressure)
-11.46
Melting Point
234.73
pKa Acid
8.58
pKa Basic
7.86
Protein Name UniProt ID Entry Name Species #Pharmacophore Points Probability (0.7 ≤ Tversky Score ≤ 1.0)
Formate--tetrahydrofolate ligase P21164 FTHS_MOOTH Moorella thermoacetica 3 0.9465
DNA-directed DNA polymerase Q38087 DPOL_BPR69 Escherichia phage RB69 3 0.9313
Chitinase A Q9AMP1 Q9AMP1_VIBHA Vibrio harveyi 3 0.9306
D-aminoacyl-tRNA deacylase Q8IIS0 DTD_PLAF7 Plasmodium falciparum 3 0.9119
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform O02697 PK3CG_PIG Sus scrofa 5 0.9115
Serine/threonine-protein kinase pim-1 P11309 PIM1_HUMAN Homo sapiens 3 0.9104
Glycogen phosphorylase, muscle form P00489 PYGM_RABIT Oryctolagus cuniculus 3 0.9103
Tyrosine-protein kinase JAK3 P52333 JAK3_HUMAN Homo sapiens 3 0.8888
Peroxisome proliferator-activated receptor gamma P37231 PPARG_HUMAN Homo sapiens 4 0.8871
Glycogen synthase kinase-3 beta P49841 GSK3B_HUMAN Homo sapiens 4 0.8851
Hygromycin-B 4-O-kinase P00557 KHYB_ECOLX Escherichia coli 4 0.8815
Toxoflavin degrading enzyme E3SET7 E3SET7_PAEPO Paenibacillus polymyxa 3 0.8725
ABC-type polar amino acid transport system, ATPase component Q8RCC2 Q8RCC2_CALS4 Caldanaerobacter subterraneus subsp. tengcongensis 3 0.8710
Metallo-beta-lactamase type 2 C7C422 BLAN1_KLEPN Klebsiella pneumoniae 3 0.8683
dTDP-4-dehydrorhamnose 3,5-epimerase A0A6L7H6N0 A0A1S0QLH9_BACAN Bacillus anthracis 4 0.8633
Transcriptional regulator, PadR-like family A2RI36 A2RI36_LACLM Lactococcus lactis subsp. cremoris 3 0.8601
Tryptophan synthase alpha chain P16608 TRPA_THET2 Thermus thermophilus 3 0.8593
Cathepsin S P25774 CATS_HUMAN Homo sapiens 3 0.8570
Glycogen synthase kinase-3 beta P49841 GSK3B_HUMAN Homo sapiens 3 0.8548
Epidermal growth factor receptor P00533 EGFR_HUMAN Homo sapiens 3 0.8541
4-hydroxyphenylacetate 3-monooxygenase Q8YHT7 Q8YHT7_BRUME Brucella melitensis biotype 1 3 0.8532
Epidermal growth factor receptor P00533 EGFR_HUMAN Homo sapiens 3 0.8517
Anthocyanidin 3-O-glucosyltransferase UFGT P51094 UFOG_VITVI Vitis vinifera 4 0.8471
Ectonucleoside triphosphate diphosphohydrolase I Q5ZUA2 Q5ZUA2_LEGPH Legionella pneumophila subsp. pneumophila 3 0.8471
Nuclear receptor subfamily 4immunitygroup A member 1 P22736 NR4A1_HUMAN Homo sapiens 3 0.8460
MAP kinase-activated protein kinase 2 P49137 MAPK2_HUMAN Homo sapiens 3 0.8424
HTH-type transcriptional repressor PurR P0ACP7 PURR_ECOLI Escherichia coli 3 0.8406
Lactotransferrin P24627 TRFL_BOVIN Bos taurus 3 0.8376
Thymidylate synthase P0A884 TYSY_ECOLI Escherichia coli 5 0.8368
Mitogen-activated protein kinase 14 Q16539 MK14_HUMAN Homo sapiens 3 0.8344
cGMP-specific 3',5'-cyclic phosphodiesterase O76074 PDE5A_HUMAN Homo sapiens 3 0.8315
Serine/threonine-protein kinase pim-1 P11309 PIM1_HUMAN Homo sapiens 3 0.8286
Nucleoside diphosphate kinase A5J299 A5J299_PENVA Penaeus vannamei 3 0.8285
L-lactate dehydrogenase A chain P13491 LDHA_RABIT Oryctolagus cuniculus 3 0.8253
Carbonic anhydrase 2 P00918 CAH2_HUMAN Homo sapiens 3 0.8225
Albumin P02768 ALBU_HUMAN Homo sapiens 3 0.8216
ADP-ribosyl-[dinitrogen reductase] hydrolase A7XNI2 A7XNI2_AZOBR Azospirillum brasilense 3 0.8211
HTH-type transcriptional repressor PurR P0ACP7 PURR_ECOLI Escherichia coli 3 0.8191
Capsid protein Q9WBP8 Q9WBP8_9VIRU Adeno-associated virus - 1 3 0.8153
Peroxisome proliferator-activated receptor gamma P37231 PPARG_HUMAN Homo sapiens 3 0.8122
O-methyltransferase family 2 D5STZ7 D5STZ7_PLAL2 Planctopirus limnophila 5 0.8110
Tetracycline repressor protein class D P0ACT4 TETR4_ECOLX Escherichia coli 3 0.8099
Isocitrate/homoisocitrate dehydrogenase Q5SIJ1 HICDH_THET8 Thermus thermophilus 3 0.8087
WxcM-like protein Q12KT8 Q12KT8_SHEDO Shewanella denitrificans 4 0.8077
Epidermal growth factor receptor P00533 EGFR_HUMAN Homo sapiens 3 0.8065
Single-stranded-DNA-specific exonuclease RecJ D0EM60 D0EM60_DEIRD Deinococcus radiodurans 3 0.8057
3'-5' exoribonuclease Rv2179c P9WJ73 EXRBN_MYCTU Mycobacterium tuberculosis 3 0.8003
Endothiapepsin P11838 CARP_CRYPA Cryphonectria parasitica 3 0.7992
Endoplasmin P41148 ENPL_CANLF Canis lupus familiaris 3 0.7965
Nucleoside diphosphate kinase Q5UQL3 NDK_MIMIV Acanthamoeba polyphaga mimivirus 3 0.7956
cAMP-dependent protein kinase type I-alpha regulatory subunit P00514 KAP0_BOVIN Bos taurus 3 0.7939
N-acetyltransferase domain-containing protein Q9HV14 Q9HV14_PSEAE Pseudomonas aeruginosa 3 0.7933
Fibroblast growth factor receptor 2 P21802 FGFR2_HUMAN Homo sapiens 3 0.7933
Valacyclovir hydrolase Q86WA6 BPHL_HUMAN Homo sapiens 3 0.7928
Histone-lysine N-methyltransferase SETD7 Q8WTS6 SETD7_HUMAN Homo sapiens 4 0.7900
Tyrosine-protein kinase Lck P06239 LCK_HUMAN Homo sapiens 3 0.7899
Nitric oxide synthase, inducible P29477 NOS2_MOUSE Mus musculus 3 0.7892
Poly [ADP-ribose] polymerase tankyrase-2 Q9H2K2 TNKS2_HUMAN Homo sapiens 4 0.7820
UTP-monosaccharide-1-phosphate uridylyltransferase D3G6S4 D3G6S4_LEIMA Leishmania major 3 0.7807
Ras-related protein Ral-B P11234 RALB_HUMAN Homo sapiens 3 0.7786
Carbonic anhydrase 2 P00918 CAH2_HUMAN Homo sapiens 3 0.7778
HTH-type transcriptional repressor PurR P0ACP7 PURR_ECOLI Escherichia coli 3 0.7776
ATP-dependent molecular chaperone HSP82 P02829 HSP82_YEAST Saccharomyces cerevisiae 3 0.7757
Fibroblast growth factor receptor 2 P21802 FGFR2_HUMAN Homo sapiens 3 0.7749
Non-receptor tyrosine-protein kinase TYK2 P29597 TYK2_HUMAN Homo sapiens 3 0.7747
Serine/threonine-protein kinase pim-1 P11309 PIM1_HUMAN Homo sapiens 3 0.7701
Fibroblast growth factor receptor 2 P21802 FGFR2_HUMAN Homo sapiens 4 0.7695
Serine/threonine-protein kinase pim-1 P11309 PIM1_HUMAN Homo sapiens 3 0.7668
Poly [ADP-ribose] polymerase tankyrase-2 Q9H2K2 TNKS2_HUMAN Homo sapiens 4 0.7654
Mitogen-activated protein kinase kinase kinase 5 Q99683 M3K5_HUMAN Homo sapiens 3 0.7653
HTH-type transcriptional repressor PurR P0ACP7 PURR_ECOLI Escherichia coli 3 0.7639
Activated CDC42 kinase 1 Q07912 ACK1_HUMAN Homo sapiens 4 0.7634
Glucose-1-phosphate thymidylyltransferase Q9AGY4 Q9AGY4_ANETH Aneurinibacillus thermoaerophilus 4 0.7627
High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A O76083 PDE9A_HUMAN Homo sapiens 5 0.7624
Poly [ADP-ribose] polymerase tankyrase-2 Q9H2K2 TNKS2_HUMAN Homo sapiens 4 0.7612
Glycerol kinase P0A6F3 GLPK_ECOLI Escherichia coli 4 0.7591
Inosine-5'-monophosphate dehydrogenase P50097 IMDH_TRIFO Tritrichomonas foetus 3 0.7586
Dipeptidyl peptidase 4 P27487 DPP4_HUMAN Homo sapiens 3 0.7580
3-hydroxy-3-methylglutaryl-coenzyme A reductase P04035 HMDH_HUMAN Homo sapiens 3 0.7577
Serine/threonine-protein kinase SKY1 Q03656 SKY1_YEAST Saccharomyces cerevisiae 3 0.7573
Aspartate-semialdehyde dehydrogenase Q51344 DHAS_PSEAE Pseudomonas aeruginosa 3 0.7569
Phosphatidylinositol 5-phosphate 4-kinase type-2 beta P78356 PI42B_HUMAN Homo sapiens 4 0.7567
Methylmalonyl-CoA decarboxylase P52045 SCPB_ECOLI Escherichia coli 3 0.7562
HTH-type transcriptional repressor PurR P0ACP7 PURR_ECOLI Escherichia coli 3 0.7550
Glucan 1,3-beta-glucosidase P29717 EXG1_CANAL Candida albicans 3 0.7539
Poly [ADP-ribose] polymerase tankyrase-2 Q9H2K2 TNKS2_HUMAN Homo sapiens 5 0.7524
Nucleoside diphosphate kinase Q381H3 Q381H3_TRYB2 Trypanosoma brucei brucei 4 0.7518
Tetracycline repressor protein class H P51561 TETR8_PASMD Pasteurella multocida 3 0.7510
HTH-type transcriptional repressor PurR P0ACP7 PURR_ECOLI Escherichia coli 3 0.7505
DNA polymerase III subunit epsilon P03007 DPO3E_ECOLI Escherichia coli 3 0.7495
Chitinase A Q9AMP1 Q9AMP1_VIBHA Vibrio harveyi 2 0.7494
Epidermal growth factor receptor P00533 EGFR_HUMAN Homo sapiens 3 0.7484
Poly [ADP-ribose] polymerase tankyrase-2 Q9H2K2 TNKS2_HUMAN Homo sapiens 4 0.7481
Serine/threonine-protein kinase pim-1 P11309 PIM1_HUMAN Homo sapiens 4 0.7477
Ribonuclease 4 P15468 RNAS4_PIG Sus scrofa 3 0.7463
NAD-capped RNA hydrolase NudC P32664 NUDC_ECOLI Escherichia coli 3 0.7461
Ribosyldihydronicotinamide dehydrogenase [quinone] P16083 NQO2_HUMAN Homo sapiens 3 0.7450
Chitinase A Q9AMP1 Q9AMP1_VIBHA Vibrio harveyi 2 0.7426
S-adenosylmethionine decarboxylase proenzyme P17707 DCAM_HUMAN Homo sapiens 4 0.7419
Leucoanthocyanidin dioxygenase Q96323 LDOX_ARATH Arabidopsis thaliana 5 0.7412
Anthocyanidin 3-O-glucosyltransferase UFGT P51094 UFOG_VITVI Vitis vinifera 3 0.7407
Tetracycline repressor protein class D P0ACT4 TETR4_ECOLX Escherichia coli 3 0.7397
Thymidylate synthase P00469 TYSY_LACCA Lacticaseibacillus casei 3 0.7395
Cyclin-dependent kinase 2 P24941 CDK2_HUMAN Homo sapiens 3 0.7394
Glucan 1,3-beta-glucosidase P29717 EXG1_CANAL Candida albicans 3 0.7387
Liver carboxylesterase 1 P23141 EST1_HUMAN Homo sapiens 3 0.7382
Cyclin-dependent kinase 2 P24941 CDK2_HUMAN Homo sapiens 3 0.7380
dTDP-4-dehydro-6-deoxyglucose 3-epimerase Q5SFD1 CHMJ_STRBI Streptomyces bikiniensis 4 0.7376
Proto-oncogene tyrosine-protein kinase Src P00523 SRC_CHICK Gallus gallus 3 0.7374
Cyclin-dependent kinase 2 P24941 CDK2_HUMAN Homo sapiens 3 0.7373
Pyruvate kinase PKM P11974 KPYM_RABIT Oryctolagus cuniculus 3 0.7365
Serine/threonine-protein kinase 24 Q9Y6E0 STK24_HUMAN Homo sapiens 3 0.7356
Putative protease I Q8A8A4 Q8A8A4_BACTN Bacteroides thetaiotaomicron 3 0.7356
DNA-directed DNA polymerase Q38087 DPOL_BPR69 Escherichia phage RB69 3 0.7352
Proto-oncogene tyrosine-protein kinase Src P00523 SRC_CHICK Gallus gallus 3 0.7351
NAD(P)H dehydrogenase [quinone] 1 P15559 NQO1_HUMAN Homo sapiens 4 0.7333
Steroid Delta-isomerase P00947 SDIS_COMTE Comamonas testosteroni 2 0.7333
Nonspecific lipid-transfer protein, putative C9ZUV7 C9ZUV7_TRYB9 Trypanosoma brucei gambiense 3 0.7328
Fructose-1,6-bisphosphatase 1 P09467 F16P1_HUMAN Homo sapiens 3 0.7326
Poly [ADP-ribose] polymerase tankyrase-2 Q9H2K2 TNKS2_HUMAN Homo sapiens 4 0.7317
Ribonuclease J H9CZL7 H9CZL7_DEIRD Deinococcus radiodurans 4 0.7313
Genome polyprotein P26663 POLG_HCVBK Hepatitis C virus genotype 1b 3 0.7313
Poly [ADP-ribose] polymerase tankyrase-2 Q9H2K2 TNKS2_HUMAN Homo sapiens 4 0.7312
Thymidylate synthase P04818 TYSY_HUMAN Homo sapiens 4 0.7309
2',3'-cyclic-nucleotide 3'-phosphodiesterase P16330 CN37_MOUSE Mus musculus 3 0.7290
Cyclin-dependent kinase 2 P24941 CDK2_HUMAN Homo sapiens 3 0.7281
DNA-directed DNA polymerase Q38087 DPOL_BPR69 Escherichia phage RB69 3 0.7278
Serine/threonine-protein kinase 24 Q9Y6E0 STK24_HUMAN Homo sapiens 4 0.7270
Death-associated protein kinase 1 P53355 DAPK1_HUMAN Homo sapiens 4 0.7267
2',3'-cyclic-nucleotide 3'-phosphodiesterase P16330 CN37_MOUSE Mus musculus 3 0.7267
Steroid Delta-isomerase P00947 SDIS_COMTE Comamonas testosteroni 2 0.7235
Bifunctional AAC/APH P0A0C1 AACA_STAAU Staphylococcus aureus 4 0.7232
High affinity transport system protein p37 P15363 P37_MYCHR Mesomycoplasma hyorhinis 3 0.7216
D-alanyl-D-alanine carboxypeptidase P15555 DAC_STRSR Streptomyces sp 3 0.7212
High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A O76083 PDE9A_HUMAN Homo sapiens 4 0.7207
Epidermal growth factor receptor P00533 EGFR_HUMAN Homo sapiens 4 0.7206
Protein ppBat Q8A8A4 Q8A8A4_BACTN Bacteroides thetaiotaomicron VPI-5482 2 0.7194
Inosine-5'-monophosphate dehydrogenase P50097 IMDH_TRIFO Tritrichomonas foetus 3 0.7181
Eukaryotic translation initiation factor 4E-1 P29557 IF4E1_WHEAT Triticum aestivum 4 0.7180
Casein kinase II subunit alpha P28523 CSK2A_MAIZE Zea mays 4 0.7176
Tubulin alpha-1B chain P81947 TBA1B_BOVIN Bos taurus 3 0.7172
cAMP-dependent protein kinase catalytic subunit alpha P00517 KAPCA_BOVIN Bos taurus 4 0.7169
MutT/nudix family protein O33199 O33199_MYCTO Mycobacterium tuberculosis 3 0.7165
3-hydroxy-3-methylglutaryl-coenzyme A reductase P04035 HMDH_HUMAN Homo sapiens 3 0.7160
DNA-directed DNA polymerase Q38087 DPOL_BPR69 Escherichia phage RB69 3 0.7156
DNA-directed DNA polymerase Q38087 DPOL_BPR69 Escherichia phage RB69 3 0.7153
3-hydroxy-3-methylglutaryl-coenzyme A reductase P04035 HMDH_HUMAN Homo sapiens 3 0.7141
Estrogen receptor P03372 ESR1_HUMAN Homo sapiens 4 0.7132
Uncharacterized protein YML079W Q03629 YMH9_YEAST Saccharomyces cerevisiae 3 0.7124
Isoflavone-7-O-methyltransferase 8 O24529 7OMT8_MEDSA Medicago sativa 5 0.7119
IOMT 3 Q06YR3 Q06YR3_MEDTR Medicago truncatula 4 0.7095
Focal adhesion kinase 1 Q05397 FAK1_HUMAN Homo sapiens 3 0.7094
Caffeic acid O-methyltransferase Q9ZTU2 Q9ZTU2_LOLPR Lolium perenne 4 0.7090
Poly [ADP-ribose] polymerase tankyrase-2 Q9H2K2 TNKS2_HUMAN Homo sapiens 4 0.7083
Thymidylate synthase P0A884 TYSY_ECOLI Escherichia coli 5 0.7082
dTDP-fucosamine acetyltransferase Q8FBQ3 WECD_ECOL6 Escherichia coli O6:H1 3 0.7075
Cell division control protein 42 homolog P60953 CDC42_HUMAN Homo sapiens 4 0.7072
Serine/threonine-protein kinase MRCK beta Q9Y5S2 MRCKB_HUMAN Homo sapiens 4 0.7061
Deoxyuridine triphosphatase, putative Q57ZH3 Q57ZH3_TRYB2 Trypanosoma brucei brucei 5 0.7058
Cyclin-dependent kinase 2 P24941 CDK2_HUMAN Homo sapiens 3 0.7058
Glycerol kinase P0A6F3 GLPK_ECOLI Escherichia coli 4 0.7057
DNA-directed DNA polymerase Q38087 DPOL_BPR69 Escherichia phage RB69 3 0.7057
Unconventional myosin-Va Q02440 MYO5A_CHICK Gallus gallus 3 0.7057
Non-receptor tyrosine-protein kinase TYK2 P29597 TYK2_HUMAN Homo sapiens 4 0.7055
Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplastic Q43088 RBCMT_PEA Pisum sativum 3 0.7052
Carbonic anhydrase 2 P00918 CAH2_HUMAN Homo sapiens 2 0.7052
Nucleoside diphosphate kinase P15266 NDK_MYXXA Myxococcus xanthus 3 0.7050
Neuropilin-1 O14786 NRP1_HUMAN Homo sapiens 3 0.7043
Nucleoside diphosphate kinase A 2 P52175 NDKA2_BOVIN Bos taurus 4 0.7040
Leucine--tRNA ligase P07813 SYL_ECOLI Escherichia coli 3 0.7039
Serine/threonine-protein kinase Chk1 O14757 CHK1_HUMAN Homo sapiens 3 0.7035
3-hydroxybenzoate 4-monooxygenase Q6SSJ6 MOBA_COMTE Comamonas testosteroni 3 0.7031
Death-associated protein kinase 1 P53355 DAPK1_HUMAN Homo sapiens 4 0.7028
16S rRNA (guanine(1405)-N(7))-methyltransferase Q763K9 Q763K9_ECOLX Escherichia coli 3 0.7024
Ribosyldihydronicotinamide dehydrogenase [quinone] P16083 NQO2_HUMAN Homo sapiens 2 0.7022
Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplastic Q43088 RBCMT_PEA Pisum sativum 3 0.7019
Hypoxanthine-guanine phosphoribosyltransferase P00492 HPRT_HUMAN Homo sapiens 4 0.7016
Small heat shock protein StHsp14.0 Q970D9 Q970D9_SULTO Sulfurisphaera tokodaii 3 0.7015
Cyclin-dependent kinase 5 Q00535 CDK5_HUMAN Homo sapiens 4 0.7003

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