3-amino-5-methyl-1H-pyrazolo[4,3-c]pyridin-4(5H)-one - Compound Card

3-amino-5-methyl-1H-pyrazolo[4,3-c]pyridin-4(5H)-one

Select a section from the left sidebar

3-amino-5-methyl-1H-pyrazolo[4,3-c]pyridin-4(5H)-one

Structure
Zoomed Structure
  • Family: Plantae - Euphorbiaceae
  • Kingdom: Plantae
  • Class: Alkaloid
    • Subclass: Pyridine Alkaloid
Canonical Smiles Cn1ccc2c(c1=O)c(N)n[nH]2
InChI InChI=1S/C7H8N4O/c1-11-3-2-4-5(7(11)12)6(8)10-9-4/h2-3H,1H3,(H3,8,9,10)
InChIKey YLMZNJDILFDRGQ-UHFFFAOYSA-N
Formula C7H8N4O
HBA 4
HBD 2
MW 164.17
Rotatable Bonds 0
TPSA 76.7
LogP -0.16
Number Rings 2
Number Aromatic Rings 2
Heavy Atom Count 12
Formal Charge 0
Fraction CSP3 0.14
Exact Mass 164.07
Number of Lipinski Rule Violations 0
# Species Family Kingdom NCBI Taxonomy ID
1 Ricinus communis Euphorbiaceae Plantae 3988

Showing of synonyms

  • El-Naggar M.H, Elgaml A, et al. (2019). Antimicrobial and antiquorum-sensing activity of Ricinus communis extracts and ricinine derivatives. Natural product research, 2019, 33(11), 1556-1562. [View] [PubMed]
Pubchem: 129518398

No compound-protein relationship available.

Structure

SMILES: c1n[nH]c(c12)cc[nH]c2=O

Level: 0

Mol. Weight: 164.17 g/mol

Antimicrobial
Antiquorum-sensing

Absorption

Caco-2 (logPapp)
-5.12
Human Oral Bioavailability 20%
Bioavailable
Human Intestinal Absorption
Absorbed
Madin-Darby Canine Kidney
-4.86
Human Oral Bioavailability 50%
Bioavailable
P-Glycoprotein Inhibitor
Non-Inhibitor
P-Glycoprotein Substrate
Non-Substrate
Skin Permeability
-1.58

Distribution

Blood-Brain Barrier (CNS)
-
Blood-Brain Barrier
Penetrable
Fraction Unbound (Human)
0.23
Plasma Protein Binding
29.5
Steady State Volume of Distribution
-

Metabolism

Breast Cancer Resistance Protein
Non-Inhibitor
CYP 1A2 Inhibitor
Non-Inhibitor
CYP 1A2 Substrate
Non-Substrate
CYP 2C19 Inhibitor
Non-Inhibitor
CYP 2C19 Substrate
Non-Substrate
CYP 2C9 Inhibitor
Non-Inhibitor
CYP 2C9 Substrate
Non-Substrate
CYP 2D6 Inhibitor
Non-Inhibitor
CYP 2D6 Substrate
Non-Substrate
CYP 3A4 Inhibitor
Non-Inhibitor
CYP 3A4 Substrate
Non-Substrate
OATP1B1
Non-Inhibitor
OATP1B3
Non-Inhibitor

Excretion

Clearance
8.65
Organic Cation Transporter 2
Non-Inhibitor
Half-Life of Drug
-

Toxicity

AMES Mutagenesis
Safe
Avian
Safe
Bee
Safe
Bioconcentration Factor
-0.39
Biodegradation
Safe
Carcinogenesis
Safe
Crustacean
Safe
Liver Injury I (DILI)
Toxic
Eye Corrosion
Safe
Eye Irritation
Safe
Maximum Tolerated Dose
0.67
Liver Injury II
Toxic
hERG Blockers
Safe
Daphnia Maga
3.39
Micronucleos
Toxic
NR-AhR
Safe
NR-AR
Safe
NR-AR-LBD
Safe
NR-Aromatase
Safe
NR-ER
Safe
NR-ER-LBD
Safe
NR-GR
Safe
NR-PPAR-gamma
Safe
NR-TR
Safe
T. Pyriformis
2.04
Rat (Acute)
2.14
Rat (Chronic Oral)
2.48
Fathead Minnow
3.54
Respiratory Disease
Toxic
Skin Sensitisation
Toxic
SR-ARE
Safe
SR-ATAD5
Safe
SR-HSE
Safe
SR-MMP
Safe
SR-p53
Safe

General Properties

Boiling Point
395.82
Hydration Free Energy
-16.02
Log(D) at pH=7.4
-0.31
Log(P)
0.17
Log S
-2.15
Log(Vapor Pressure)
-7.55
Melting Point
314.03
pKa Acid
8.33
pKa Basic
7.2
Protein Name UniProt ID Entry Name Species #Pharmacophore Points Probability (0.7 ≤ Tversky Score ≤ 1.0)
glutaryl-CoA dehydrogenase (ETF) Q3JP94 Q3JP94_BURP1 Burkholderia pseudomallei 3 0.9743
MAP kinase-activated protein kinase 2 P49137 MAPK2_HUMAN Homo sapiens 3 0.9576
Glycogen synthase kinase-3 beta P49841 GSK3B_HUMAN Homo sapiens 3 0.9546
3-phosphoinositide-dependent protein kinase 1 O15530 PDPK1_HUMAN Homo sapiens 4 0.9502
Serine/threonine-protein kinase SKY1 Q03656 SKY1_YEAST Saccharomyces cerevisiae 3 0.9502
LIM domain kinase 1 P53667 LIMK1_HUMAN Homo sapiens 3 0.9486
Succinate dehydrogenase flavoprotein subunit P0AC41 SDHA_ECOLI Escherichia coli 3 0.9413
Serine/threonine-protein kinase Chk1 O14757 CHK1_HUMAN Homo sapiens 4 0.9397
Pteridine reductase, putative Q581W1 Q581W1_TRYB2 Trypanosoma brucei brucei 3 0.9370
ADP compounds hydrolase NudE P45799 NUDE_ECOLI Escherichia coli 3 0.9365
Capsid protein Q9WBP8 Q9WBP8_9VIRU Adeno-associated virus - 1 3 0.9361
Ephrin type-B receptor 2 P54763 EPHB2_MOUSE Mus musculus 3 0.9326
RIO-type serine/threonine-protein kinase Rio1 O28471 RIO1_ARCFU Archaeoglobus fulgidus 3 0.9298
3',5'-cyclic-AMP phosphodiesterase 4D Q08499 PDE4D_HUMAN Homo sapiens 3 0.9297
5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase P0AF12 MTNN_ECOLI Escherichia coli 3 0.9269
Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase F6MZ55 F6MZ55_9FIRM Sporomusa ovata 3 0.9230
Fibroblast growth factor receptor 2 P21802 FGFR2_HUMAN Homo sapiens 3 0.9186
3',5'-cyclic-AMP phosphodiesterase 4D Q08499 PDE4D_HUMAN Homo sapiens 3 0.9152
ATP-dependent molecular chaperone HSP82 P02829 HSP82_YEAST Saccharomyces cerevisiae 3 0.9151
Mitogen-activated protein kinase kinase kinase 5 Q99683 M3K5_HUMAN Homo sapiens 3 0.9120
Fibroblast growth factor receptor 2 P21802 FGFR2_HUMAN Homo sapiens 3 0.9111
Queuine tRNA-ribosyltransferase P28720 TGT_ZYMMO Zymomonas mobilis subsp. mobilis 3 0.9106
Poly [ADP-ribose] polymerase 1 P09874 PARP1_HUMAN Homo sapiens 3 0.9067
Serine/threonine-protein kinase toxin HipA P23874 HIPA_ECOLI Escherichia coli 3 0.9066
HTH-type transcriptional repressor PurR P0ACP7 PURR_ECOLI Escherichia coli 3 0.9013
Casein kinase II subunit alpha P68400 CSK21_HUMAN Homo sapiens 3 0.9005
Albumin P02768 ALBU_HUMAN Homo sapiens 3 0.8999
Poly [ADP-ribose] polymerase 1 P09874 PARP1_HUMAN Homo sapiens 3 0.8917
Diphtheria toxin P00588 DTX_CORBE Corynephage beta 3 0.8904
NAD(P)H-hydrate epimerase Q8K4Z3 NNRE_MOUSE Mus musculus 3 0.8886
cAMP-dependent protein kinase catalytic subunit alpha P05132 KAPCA_MOUSE Mus musculus 3 0.8845
HTH-type transcriptional repressor PurR P0ACP7 PURR_ECOLI Escherichia coli 3 0.8759
Protein mono-ADP-ribosyltransferase PARP3 Q9Y6F1 PARP3_HUMAN Homo sapiens 3 0.8716
Acetylcholinesterase P21836 ACES_MOUSE Mus musculus 3 0.8666
Heat shock protein HSP 90-alpha P07900 HS90A_HUMAN Homo sapiens 3 0.8590
Poly [ADP-ribose] polymerase tankyrase-2 Q9H2K2 TNKS2_HUMAN Homo sapiens 3 0.8543
Poly [ADP-ribose] polymerase 1 P09874 PARP1_HUMAN Homo sapiens 3 0.8542
Thiamine-phosphate synthase P39594 THIE_BACSU Bacillus subtilis 3 0.8469
Aminoglycoside N(3)-acetyltransferase A0A3P1UCA6 Q81P86_BACAN Bacillus anthracis 3 0.8468
Dual specificity mitogen-activated protein kinase kinase 1 Q02750 MP2K1_HUMAN Homo sapiens 3 0.8466
Nitric oxide synthase, inducible P29477 NOS2_MOUSE Mus musculus 3 0.8426
Lactoperoxidase P80025 PERL_BOVIN Bos taurus 3 0.8365
Cyclin-dependent kinase 2 P24941 CDK2_HUMAN Homo sapiens 4 0.8360
Thiamine-phosphate synthase P39594 THIE_BACSU Bacillus subtilis 3 0.8304
Poly [ADP-ribose] polymerase tankyrase-2 Q9H2K2 TNKS2_HUMAN Homo sapiens 3 0.8292
Cytidine and deoxycytidylate deaminase zinc-binding region Q82Y41 Q82Y41_NITEU Nitrosomonas europaea 3 0.8291
Phenylalanine-4-hydroxylase P00439 PH4H_HUMAN Homo sapiens 3 0.8272
Cytochrome P450 2E1 P05181 CP2E1_HUMAN Homo sapiens 3 0.8236
HTH-type transcriptional repressor PurR P0ACP7 PURR_ECOLI Escherichia coli 3 0.8210
Cyclin-dependent kinase 2 P24941 CDK2_HUMAN Homo sapiens 4 0.8204
Nitric oxide synthase, inducible P29477 NOS2_MOUSE Mus musculus 3 0.8184
Biphenyl-2,3-diol 1,2-dioxygenase P17297 BPHC_PSES1 Pseudomonas sp 3 0.8155
Poly [ADP-ribose] polymerase 1 P09874 PARP1_HUMAN Homo sapiens 3 0.8127
Queuine tRNA-ribosyltransferase P28720 TGT_ZYMMO Zymomonas mobilis subsp. mobilis 3 0.8071
Acetylcholinesterase P04058 ACES_TETCF Tetronarce californica 3 0.8052
Acetylcholinesterase P21836 ACES_MOUSE Mus musculus 3 0.8047
Toxoflavin degrading enzyme E3SET7 E3SET7_PAEPO Paenibacillus polymyxa 3 0.8014
Calmodulin-1 P0DP29 CALM1_RAT Rattus norvegicus 3 0.8006
Acetylcholinesterase P04058 ACES_TETCF Tetronarce californica 3 0.8003
5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase Q81LL4 MTNN_BACAN Bacillus anthracis 3 0.7997
Acetylcholinesterase P22303 ACES_HUMAN Homo sapiens 3 0.7992
Thymidine kinase P0DTH5 KITH_HHV11 Human herpesvirus 1 2 0.7986
Pteridine reductase, putative Q581W1 Q581W1_TRYB2 Trypanosoma brucei brucei 3 0.7979
Retinoic acid receptor RXR-alpha P19793 RXRA_HUMAN Homo sapiens 3 0.7963
NADH:flavin oxidoreductase Sye1 Q8EEC8 Q8EEC8_SHEON Shewanella oneidensis 3 0.7950
Mitogen-activated protein kinase 1 P28482 MK01_HUMAN Homo sapiens 3 0.7943
Phenylalanine-4-hydroxylase P00439 PH4H_HUMAN Homo sapiens 3 0.7928
Biphenyl-2,3-diol 1,2-dioxygenase P17297 BPHC_PSES1 Pseudomonas sp 3 0.7898
Eugenol synthase 1 Q15GI4 EGS1_OCIBA Ocimum basilicum 3 0.7866
Sulfotransferase 2B1 O00204 ST2B1_HUMAN Homo sapiens 2 0.7795
Fibroblast growth factor receptor 2 P21802 FGFR2_HUMAN Homo sapiens 3 0.7767
S-adenosylmethionine decarboxylase proenzyme P17707 DCAM_HUMAN Homo sapiens 3 0.7760
Purine nucleoside phosphorylase DeoD-type P0ABP8 DEOD_ECOLI Escherichia coli 3 0.7756
Gag-Pol polyprotein P04585 POL_HV1H2 Human immunodeficiency virus type 1 group M subtype B 3 0.7753
Putative S-adenosyl-L-methionine-dependent methyltransferase ML2640 Q9CCZ4 Y2640_MYCLE Mycobacterium leprae 3 0.7709
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 P04191 AT2A1_RABIT Oryctolagus cuniculus 2 0.7695
Methionine aminopeptidase P0AE18 MAP1_ECOLI Escherichia coli 3 0.7686
ATP-dependent molecular chaperone HSP82 P02829 HSP82_YEAST Saccharomyces cerevisiae 3 0.7680
17-beta-hydroxysteroid dehydrogenase type 1 P14061 DHB1_HUMAN Homo sapiens 2 0.7630
Chloramphenicol acetyltransferase P62577 CAT_ECOLX Escherichia coli 2 0.7625
Steroid Delta-isomerase P00947 SDIS_COMTE Comamonas testosteroni 2 0.7599
Endoplasmin P41148 ENPL_CANLF Canis lupus familiaris 3 0.7597
Pheromone-binding protein ASP1 Q9U9J6 Q9U9J6_APIME Apis mellifera 2 0.7583
Polymerase acidic protein C3W5S0 C3W5S0_I09A0 Influenza A virus 2 0.7573
Beta-secretase 1 P56817 BACE1_HUMAN Homo sapiens 2 0.7560
Cyclin-dependent kinase 9 P50750 CDK9_HUMAN Homo sapiens 3 0.7559
cAMP-dependent protein kinase catalytic subunit alpha P17612 KAPCA_HUMAN Homo sapiens 2 0.7558
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform P48736 PK3CG_HUMAN Homo sapiens 3 0.7534
Carminomycin 4-O-methyltransferase DnrK Q06528 DNRK_STRPE Streptomyces peucetius 2 0.7524
Fructose-1,6-bisphosphatase 1 P00636 F16P1_PIG Sus scrofa 3 0.7523
Casein kinase II subunit alpha P68400 CSK21_HUMAN Homo sapiens 3 0.7523
Acetylcholinesterase P04058 ACES_TETCF Tetronarce californica 2 0.7519
Lethal(3)malignant brain tumor-like protein 1 Q9Y468 LMBL1_HUMAN Homo sapiens 3 0.7513
Steroid Delta-isomerase P07445 SDIS_PSEPU Pseudomonas putida 2 0.7507
Type II methyltransferase M.TaqI P14385 MTTA_THEAQ Thermus aquaticus 3 0.7503
Steroid Delta-isomerase P00947 SDIS_COMTE Comamonas testosteroni 2 0.7496
Type II methyltransferase M.TaqI P14385 MTTA_THEAQ Thermus aquaticus 3 0.7491
Cyclin-dependent kinase 9 P50750 CDK9_HUMAN Homo sapiens 3 0.7481
Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase Q05603 COBT_SALTY Salmonella typhimurium 3 0.7480
Tyrosine-protein kinase ABL1 P00519 ABL1_HUMAN Homo sapiens 3 0.7470
Prothrombin P00734 THRB_HUMAN Homo sapiens 3 0.7463
Rifampin ADP-ribosyl transferase A0QRS5 A0QRS5_MYCS2 Mycolicibacterium smegmatis155) 3 0.7458
Peripheral plasma membrane protein CASK O14936 CSKP_HUMAN Homo sapiens 3 0.7448
Epidermal growth factor receptor P00533 EGFR_HUMAN Homo sapiens 3 0.7443
Estrogen receptor P03372 ESR1_HUMAN Homo sapiens 2 0.7442
uroporphyrinogen-III C-methyltransferase P95417 P95417_PSEAI Pseudomonas aeruginosa 3 0.7432
Tryptophan synthase alpha chain P00929 TRPA_SALTY Salmonella typhimurium 3 0.7422
Aldo-keto reductase family 1 member C2 P52895 AK1C2_HUMAN Homo sapiens 2 0.7414
Steroid Delta-isomerase P00947 SDIS_COMTE Comamonas testosteroni 2 0.7409
cAMP-dependent protein kinase catalytic subunit alpha P00517 KAPCA_BOVIN Bos taurus 2 0.7402
Bifunctional dihydrofolate reductase-thymidylate synthase P13922 DRTS_PLAFK Plasmodium falciparum 2 0.7396
Soluble acetylcholine receptor Q8WSF8 Q8WSF8_APLCA Aplysia californica 2 0.7394
Cyclin-dependent kinase 2 P24941 CDK2_HUMAN Homo sapiens 3 0.7390
Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase Q05603 COBT_SALTY Salmonella typhimurium 3 0.7384
Serine/threonine-protein kinase Chk1 O14757 CHK1_HUMAN Homo sapiens 3 0.7381
Protein kinase C iota type Q62074 KPCI_MOUSE Mus musculus 3 0.7373
Genome polyprotein A0EKU1 A0EKU1_9FLAV Meaban virus 3 0.7368
Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplastic Q43088 RBCMT_PEA Pisum sativum 3 0.7367
Maltokinase A1TH50 MAK_MYCVP Mycolicibacterium vanbaalenii 3 0.7356
Nitric oxide synthase oxygenase O34453 NOSO_BACSU Bacillus subtilis 3 0.7355
Peripheral plasma membrane protein CASK O14936 CSKP_HUMAN Homo sapiens 3 0.7347
NAD(P)H-hydrate epimerase Q8K4Z3 NNRE_MOUSE Mus musculus 3 0.7346
Aurora kinase A O14965 AURKA_HUMAN Homo sapiens 3 0.7345
Serine/threonine-protein kinase pim-1 P11309 PIM1_HUMAN Homo sapiens 2 0.7345
SRSF protein kinase 1 Q96SB4 SRPK1_HUMAN Homo sapiens 3 0.7342
Prothrombin P00734 THRB_HUMAN Homo sapiens 3 0.7339
Poly [ADP-ribose] polymerase tankyrase-2 Q9H2K2 TNKS2_HUMAN Homo sapiens 3 0.7330
Achbp I6L8L2 I6L8L2_CAPTE Capitella teleta 3 0.7329
Mitogen-activated protein kinase kinase kinase 21 Q5TCX8 M3K21_HUMAN Homo sapiens 3 0.7324
Death-associated protein kinase 1 P53355 DAPK1_HUMAN Homo sapiens 3 0.7321
Rhodopsin kinase GRK1 P28327 GRK1_BOVIN Bos taurus 3 0.7316
Mitogen-activated protein kinase 1 P63086 MK01_RAT Rattus norvegicus 3 0.7314
Fibroblast growth factor receptor 2 P21802 FGFR2_HUMAN Homo sapiens 3 0.7313
Genome polyprotein P12823 POLG_DEN2P Dengue virus type 2 3 0.7309
Proto-oncogene tyrosine-protein kinase receptor Ret P07949 RET_HUMAN Homo sapiens 3 0.7307
Aurora kinase A O14965 AURKA_HUMAN Homo sapiens 3 0.7304
Endoplasmin P41148 ENPL_CANLF Canis lupus familiaris 3 0.7298
Cyclin-dependent kinase 9 P50750 CDK9_HUMAN Homo sapiens 3 0.7297
GTP 3',8-cyclase P69848 MOAA_STAA8 Staphylococcus aureus 3 0.7289
Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplastic Q43088 RBCMT_PEA Pisum sativum 3 0.7286
histone deacetylase A5H660 A5H660_SCHMA Schistosoma mansoni 3 0.7283
Rhodopsin kinase GRK1 P28327 GRK1_BOVIN Bos taurus 3 0.7281
NAD-dependent protein deacetylase Q9WYW0 NPD_THEMA Thermotoga maritima 3 0.7266
Serine/threonine-protein kinase 24 Q9Y6E0 STK24_HUMAN Homo sapiens 3 0.7263
Rho-associated protein kinase 1 Q13464 ROCK1_HUMAN Homo sapiens 3 0.7261
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 Q9Y3Q4 HCN4_HUMAN Homo sapiens 3 0.7251
Aurora kinase A O14965 AURKA_HUMAN Homo sapiens 3 0.7238
Death-associated protein kinase 1 P53355 DAPK1_HUMAN Homo sapiens 3 0.7235
Serine/threonine-protein kinase PLK Q4KMI8 Q4KMI8_DANRE Danio rerio 3 0.7235
Serine/threonine-protein kinase Chk1 O14757 CHK1_HUMAN Homo sapiens 3 0.7228
Hygromycin-B 4-O-kinase P00557 KHYB_ECOLX Escherichia coli 3 0.7227
Methyltransferase D0VX01 D0VX01_WSLV Wesselsbron virus 3 0.7222
Fibroblast growth factor receptor 2 P21802 FGFR2_HUMAN Homo sapiens 3 0.7219
Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplastic Q43088 RBCMT_PEA Pisum sativum 3 0.7217
Fibroblast growth factor receptor 2 P21802 FGFR2_HUMAN Homo sapiens 3 0.7209
Ribosomal protein S6 kinase alpha-1 Q15418 KS6A1_HUMAN Homo sapiens 3 0.7200
Genome polyprotein P29991 POLG_DEN27 Dengue virus type 2 3 0.7193
Queuine tRNA-ribosyltransferase P28720 TGT_ZYMMO Zymomonas mobilis subsp. mobilis 2 0.7193
Genome polyprotein P12823 POLG_DEN2P Dengue virus type 2 3 0.7190
Aurora kinase A O14965 AURKA_HUMAN Homo sapiens 3 0.7188
Proto-oncogene tyrosine-protein kinase receptor Ret P07949 RET_HUMAN Homo sapiens 3 0.7188
Aurora kinase A O14965 AURKA_HUMAN Homo sapiens 3 0.7186
Queuine tRNA-ribosyltransferase P28720 TGT_ZYMMO Zymomonas mobilis subsp. mobilis 3 0.7180
Histone-lysine N-methyltransferase SETD7 Q8WTS6 SETD7_HUMAN Homo sapiens 3 0.7173
Carbonic anhydrase 2 P00918 CAH2_HUMAN Homo sapiens 2 0.7173
Polyamine aminopropyltransferase Q5SK28 SPEE_THET8 Thermus thermophilus 3 0.7172
Phosphatidylinositol 5-phosphate 4-kinase type-2 beta P78356 PI42B_HUMAN Homo sapiens 3 0.7167
Serine/threonine-protein kinase RIO1 Q9BRS2 RIOK1_HUMAN Homo sapiens 3 0.7147
Basic phospholipase A2 VRV-PL-VIIIa P59071 PA2B8_DABRR Daboia russelii 3 0.7147
Eukaryotic translation initiation factor 2 subunit alpha P20459 IF2A_YEAST Saccharomyces cerevisiae 3 0.7144
Mitogen-activated protein kinase kinase kinase 7 O43318 M3K7_HUMAN Homo sapiens 3 0.7138
Activated CDC42 kinase 1 Q07912 ACK1_HUMAN Homo sapiens 3 0.7135
TDP-4-oxo-6-deoxy-alpha-D-glucose-3,4-oxoisomerase Q6T1W8 FDTA_ANETH Aneurinibacillus thermoaerophilus 3 0.7133
Albumin P02768 ALBU_HUMAN Homo sapiens 2 0.7133
Acetylcholinesterase P04058 ACES_TETCF Tetronarce californica 3 0.7123
Aurora kinase A O14965 AURKA_HUMAN Homo sapiens 3 0.7120
Retinoic acid receptor RXR-alpha P19793 RXRA_HUMAN Homo sapiens 2 0.7116
Beta-secretase 1 P56817 BACE1_HUMAN Homo sapiens 2 0.7116
Hygromycin-B 4-O-kinase P00557 KHYB_ECOLX Escherichia coli 3 0.7113
cGMP-dependent 3',5'-cyclic phosphodiesterase O00408 PDE2A_HUMAN Homo sapiens 2 0.7109
Dihydropteroate synthase Q81VW8 Q81VW8_BACAN Bacillus anthracis 3 0.7107
Adenosine deaminase P03958 ADA_MOUSE Mus musculus 3 0.7100
High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A O76083 PDE9A_HUMAN Homo sapiens 2 0.7074
Serine/threonine-protein kinase PLK1 P53350 PLK1_HUMAN Homo sapiens 3 0.7072
Actin, alpha skeletal muscle P68135 ACTS_RABIT Oryctolagus cuniculus 3 0.7058
Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial Q8N5Z0 AADAT_HUMAN Homo sapiens 2 0.7058
Queuine tRNA-ribosyltransferase P28720 TGT_ZYMMO Zymomonas mobilis subsp. mobilis 3 0.7058
APH(2'')-Id O68183 O68183_ENTCA Enterococcus casseliflavus 3 0.7056
Purine nucleoside phosphorylase DeoD-type O34925 DEOD_BACSU Bacillus subtilis 2 0.7052
Sulfotransferase 1A1 P50225 ST1A1_HUMAN Homo sapiens 3 0.7050
Acetylcholinesterase P04058 ACES_TETCF Tetronarce californica 3 0.7041
3',5'-cyclic-AMP phosphodiesterase 4A P27815 PDE4A_HUMAN Homo sapiens 3 0.7039
Pheromone-binding protein ASP1 Q9U9J6 Q9U9J6_APIME Apis mellifera 2 0.7030
HTH-type transcriptional repressor PurR P0ACP7 PURR_ECOLI Escherichia coli 3 0.7026
Mitogen-activated protein kinase 8 P45983 MK08_HUMAN Homo sapiens 3 0.7025
Queuine tRNA-ribosyltransferase P28720 TGT_ZYMMO Zymomonas mobilis subsp. mobilis 4 0.7023
Heat shock protein HSP 90-alpha P07900 HS90A_HUMAN Homo sapiens 3 0.7013
Histidine kinase 4 Q9C5U0 AHK4_ARATH Arabidopsis thaliana 3 0.7009
Eugenol synthase 1 Q15GI4 EGS1_OCIBA Ocimum basilicum 3 0.7006
Cyclin-dependent kinase 2 P24941 CDK2_HUMAN Homo sapiens 3 0.7004

Download SDF