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16 Families
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| # | Family | Kingdom | #Compounds | #Species |
| 1 | Dematiaceae | Fungi | 8 | 1 |
| 2 | Dendrophylliidae | Animalia | 10 | 1 |
| 3 | Desmacellidae | Animalia | 8 | 1 |
| 4 | Diadematidae | Plantae | 4 | 1 |
| 5 | Dichapetalaceae | Plantae | 4 | 1 |
| 6 | Dictyonellidae | Animalia | 12 | 1 |
| 7 | Dictyotaceae | Plantae | 12 | 4 |
| 8 | Didemnidae | Animalia | 2 | 1 |
| 9 | Didymellaceae | Fungi | 9 | 1 |
| 10 | Dilleniaceae | Plantae | 4 | 1 |
| 11 | Dioncophyllaceae | Plantae | 14 | 2 |
| 12 | Dioscoreaceae | Plantae | 20 | 3 |
| 13 | Dipsacaceae | Plantae | 5 | 2 |
| 14 | Dipterocarpaceae | Plantae | 23 | 1 |
| 15 | Dracaenaceae | Plantae | 51 | 3 |
| 16 | Dysideidae | Animalia | 2 | 1 |
