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206 Species
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| # | Species | Most Recent Name | Kingdom | Family | NCBI Taxonomy | #Compounds | #References |
| 101 | Sida spinosa | Plantae | Malvaceae | 108380 | 14 | 1 | |
| 102 | Sideritis moorei | Sideritis hirsuta | Plantae | Lamiaceae | 3394641 | 15 | 1 |
| 103 | Silene arenarioides | Plantae | Caryophyllaceae | 1937741 | 2 | 1 | |
| 104 | Silene cucubalus | Silene | Plantae | Caryophyllaceae | 3573 | 2 | 1 |
| 105 | Silene gallica | Plantae | Caryophyllaceae | 3575 | 11 | 1 | |
| 106 | Silybum marianum | Plantae | Asteraceae-Compositae | 92921 | 17 | 3 | |
| 107 | Simplicillium subtropicum | Fungi | Cordycipitaceae | 935212 | 2 | 1 | |
| 108 | Sinularia candidula | Sclerophytum polydactylum | Animalia | Alcyoniidae | 3286459 | 4 | 1 |
| 109 | Sinularia gardineri | Animalia | Alcyoniidae | 668426 | 4 | 1 | |
| 110 | Siphonochalina siphonella | Callyspongia siphonella | Animalia | Callyspongiidae | 469330 | 14 | 3 |
| 111 | Siphonochalina species | Siphonochalina | Animalia | Callyspongiidae | 412817 | 3 | 1 |
| 112 | Siphonochilus aethiopicus | Plantae | Zingiberaceae | 199663 | 4 | 1 | |
| 113 | Sisymbrium irio | Plantae | Sisymbrieae | 3730 | 6 | 1 | |
| 114 | Smyrnium olusatrum | Plantae | Apiaceae | 40962 | 7 | 1 | |
| 115 | Solanecio angulatus | Plantae | Asteraceae-Compositae | 1670880 | 13 | 1 | |
| 116 | Solanecio mannii | Plantae | Asteraceae-Compositae | - | 13 | 1 | |
| 117 | Solanecio tuberosus var. tuberosus | Solanecio | Plantae | Asteraceae-Compositae | 189251 | 13 | 1 |
| 118 | Solanum aculeastrum | Plantae | Solanaceae | 329759 | 3 | 1 | |
| 119 | Solanum diphyllum | Plantae | Solanaceae | 693386 | 1 | 1 | |
| 120 | Solanum distichum | Solanum anguivi | Plantae | Solanaceae | 329760 | 2 | 1 |
| 121 | Solanum gilo Raddi | Solanum aethiopicum | Plantae | Solanaceae | 205524 | 1 | 1 |
| 122 | Solanum nigrum | Plantae | Solanaceae | 4112 | 16 | 3 | |
| 123 | Solanum sodomaeum | Solanum | Plantae | Solanaceae | 4107 | 5 | 2 |
| 124 | Solanum tuberosum | Plantae | Solanaceae | 4113 | 3 | 1 | |
| 125 | Solanum wrightii | Plantae | Solanaceae | 374009 | 3 | 1 | |
| 126 | Solenanthus lanatus | Solenanthus | Plantae | Boraginaceae | 909324 | 3 | 1 |
| 127 | Solenostemma argel | Plantae | Apocynaceae | 219273 | 46 | 10 | |
| 128 | Sonchus acaulis | Plantae | Asteraceae-Compositae | 50191 | 5 | 1 | |
| 129 | Sonchus arvensis | Plantae | Asteraceae-Compositae | 50192 | 7 | 1 | |
| 130 | Sonchus asper | Plantae | Asteraceae-Compositae | 50193 | 10 | 2 | |
| 131 | Sonchus bipontini | Plantae | Asteraceae-Compositae | 381729 | 5 | 1 | |
| 132 | Sonchus bourgeaui | Sonchus bourgeauii | Plantae | Asteraceae-Compositae | 50194 | 4 | 1 |
| 133 | Sonchus brachylobus | Plantae | Asteraceae-Compositae | 50195 | 6 | 1 | |
| 134 | Sonchus brachyotus | Plantae | Asteraceae-Compositae | 381730 | 6 | 1 | |
| 135 | Sonchus canariensis | Plantae | Asteraceae-Compositae | 50196 | 3 | 1 | |
| 136 | Sonchus congestus | Plantae | Asteraceae-Compositae | 50197 | 5 | 1 | |
| 137 | Sonchus crassifolius | Plantae | Asteraceae-Compositae | 381731 | 5 | 1 | |
| 138 | Sonchus fauces-orci | Plantae | Asteraceae-Compositae | 50199 | 8 | 1 | |
| 139 | Sonchus fruticosus | Plantae | Asteraceae-Compositae | 50200 | 5 | 1 | |
| 140 | Sonchus gandogeri | Plantae | Asteraceae-Compositae | 50201 | 5 | 1 | |
| 141 | Sonchus gomerensis | Plantae | Asteraceae-Compositae | 1519691 | 7 | 1 | |
| 142 | Sonchus gummifer | Plantae | Asteraceae-Compositae | 159710 | 4 | 1 | |
| 143 | Sonchus hierrensis | Plantae | Asteraceae-Compositae | 50203 | 6 | 1 | |
| 144 | Sonchus hydrophilus | Plantae | Asteraceae-Compositae | 255580 | 4 | 1 | |
| 145 | Sonchus lidii | Sonchus | Plantae | Asteraceae-Compositae | 50190 | 7 | 1 |
| 146 | Sonchus luxurians | Plantae | Asteraceae-Compositae | 50205 | 6 | 1 | |
| 147 | Sonchus macrocarpus | Plantae | Asteraceae-Compositae | 2984305 | 20 | 3 | |
| 148 | Sonchus maritimus | Plantae | Asteraceae-Compositae | 50206 | 5 | 1 | |
| 149 | Sonchus melanolepis | Melanolepis | Plantae | Asteraceae-Compositae | 212303 | 6 | 1 |
| 150 | Sonchus nanus | Sonchus | Plantae | Asteraceae-Compositae | 50190 | 6 | 1 |
| 151 | Sonchus oleraceus | Plantae | Asteraceae-Compositae | 50207 | 4 | 1 | |
| 152 | Sonchus palmensis | Plantae | Asteraceae-Compositae | 50209 | 6 | 1 | |
| 153 | Sonchus pinnatifidus | Plantae | Asteraceae-Compositae | 50211 | 6 | 1 | |
| 154 | Sonchus pinnatus | Plantae | Asteraceae-Compositae | 50212 | 6 | 1 | |
| 155 | Sonchus radicatus | Plantae | Asteraceae-Compositae | 332207 | 1 | 1 | |
| 156 | Sonchus schweinfurthii | Plantae | Asteraceae-Compositae | 50213 | 7 | 1 | |
| 157 | Sonchus tenerrimus | Plantae | Asteraceae-Compositae | 255578 | 4 | 1 | |
| 158 | Sonchus ustulatus | Plantae | Asteraceae-Compositae | 50215 | 7 | 1 | |
| 159 | Sordaria sp. | Plantae | Sordariaceae | 1769487 | 3 | 1 | |
| 160 | Sorindeia juglandifolia | Plantae | Anacardiaceae | 1317886 | 8 | 2 | |
| 161 | Spathodea campanulata | Plantae | Bignoniaceae | 211926 | 2 | 1 | |
| 162 | Spergula fallax | Plantae | Caryophyllaceae | 1423401 | 5 | 1 | |
| 163 | Spergularia marginata | Spergularia | Plantae | Caryophyllaceae | 157640 | 4 | 1 |
| 164 | Sphaeranthus bullatus | Plantae | Asteraceae-Compositae | 1548657 | 11 | 1 | |
| 165 | Sphaeranthus suaveolens | Plantae | Asteraceae-Compositae | 1548666 | 9 | 1 | |
| 166 | Sphaerococcus coronopifolius | Plantae | Sphaerococcaceae | 31467 | 4 | 1 | |
| 167 | Sphaerocoryne gracilis | Plantae | Annonaceae | 489348 | 11 | 1 | |
| 168 | Sphaeropsis sapinea | Diplodia sapinea | Fungi | Cypress | 66738 | 9 | 1 |
| 169 | Spinacia oleracea | Plantae | Chenopodiaceae | 3562 | 1 | 1 | |
| 170 | Stachys aegyptiaca | Plantae | Lamiaceae | 1391947 | 23 | 5 | |
| 171 | Stachys aegyptiaca | Plantae | Labiateae | 1391947 | 3 | 1 | |
| 172 | Stachys mialhesi | Stachys | Plantae | Lamiaceae | 53171 | 2 | 1 |
| 173 | Stachys rosea | Stachys | Plantae | Lamiaceae | 53171 | 3 | 1 |
| 174 | Stapelia variegata | Orbea variegata | Plantae | Apocynaceae | 141497 | 13 | 1 |
| 175 | Staudtia kamerunensis | Plantae | Myristicaceae | 224908 | 6 | 1 | |
| 176 | Stemphylium globuliferum | Fungi | Pleosporaceae | 245170 | 16 | 2 | |
| 177 | Sterculia setigera | Sterculia | Plantae | Sterculiaceae | 66667 | 4 | 1 |
| 178 | Stereospermum acuminatissimum | Plantae | Bignoniaceae | 2708984 | 4 | 1 | |
| 179 | Stereospermum zenkeri | Stereospermum | Plantae | Bignoniaceae | 260324 | 5 | 1 |
| 180 | Streptomyces species Eg8. | Streptomyces | Monera | Streptomycetaceae | 1883 | 3 | 1 |
| 181 | Streptomyces toxytricini | Monera | Streptomycetaceae | 67369 | 1 | 1 | |
| 182 | Streptomyces youssoufiensis | Monera | Streptomycetaceae | 654447 | 3 | 1 | |
| 183 | Strychnos cocculoides | Plantae | Loganiaceae | 1040870 | 6 | 1 | |
| 184 | Strychnos gossweileri | Strychnos | Plantae | Loganiaceae | 26496 | 1 | 1 |
| 185 | Strychnos guianensis | Plantae | Loganiaceae | 1040886 | 1 | 1 | |
| 186 | Strychnos henningsii | Plantae | Loganiaceae | 1040887 | 2 | 1 | |
| 187 | Strychnos icaja | Plantae | Loganiaceae | 1040889 | 17 | 3 | |
| 188 | Strychnos moandaensis | Strychnos | Plantae | Loganiaceae | 26496 | 1 | 1 |
| 189 | Strychnos usambarensis | Plantae | Loganiaceae | 992791 | 20 | 4 | |
| 190 | Stuhlmannia moavi | Plantae | Caesalpiniaceae | 191956 | 7 | 1 | |
| 191 | Stylissa species | Stylissa | Animalia | Dictyonellidae | 237127 | 12 | 1 |
| 192 | Suaeda maritima | Plantae | Chenopodiaceae | 126913 | 5 | 1 | |
| 193 | Suberea mollis | Suberea | Animalia | Aplysinellidae | 1161115 | 15 | 2 |
| 194 | Swietenia mahogani | Swietenia mahagoni | Plantae | Meliaceae | 459165 | 23 | 3 |
| 195 | Syagrus romanzoffiana | Plantae | Arecaceae | 290277 | 22 | 1 | |
| 196 | Symphonia globulifera | Plantae | Guttiferae | 156483 | 11 | 2 | |
| 197 | Symphonia globulifera | Plantae | Clusiaceae | 156483 | 16 | 2 | |
| 198 | Synadenium grantii | Euphorbia grantii | Plantae | Euphorbiaceae | 213049 | 4 | 1 |
| 199 | Synaptolepis kirkii | Plantae | Thymelaeaceae | 2896602 | 10 | 4 | |
| 200 | Syncerus caffer | Animalia | Bovidae | 9970 | 14 | 1 | |